Publications: Zane Perkins
Markle A, Vissapragada R, Sabr K, Perkins ZB, De’Ath HD
(
2026
)
.
Pre-morbid statin use and mortality in trauma: a systematic review and meta-analysis
.
Langenbeck's Archives of Surgery
vol.
411
,
(
1
)
Singh Y, Kersey A, Lauria A, Yet B, Tai N, Rasmussen T, Ratnayake A, Perkins Z et al.
(
2026
)
.
An updated meta-analysis of prognostic factors for secondary amputation following surgical repair of lower-extremity vascular trauma in both civilian and military populations
.
Journal of Trauma and Acute Care Surgery
vol.
100
,
(
6
)
961
-
972
.
Hurst T, Perkins Z, Lockey D
(
2026
)
.
Penetrating Injury to Heart: Pre-hospital and Emergency Department Management
.
Emergency Cardiac Surgery
,
Springer Nature
Nijhawan A, Avest ET, Twohig CJ, Webster SJ, Morris J, Lendrum R, Fitzpatrick-Swallow V, Lockey DJ et al.
(
2026
)
.
Epidemiology of trauma deaths across a mature regional trauma system: patterns of pre-hospital and in-hospital fatalities
.
British Journal of Surgery
Ng W-H, Bath MF, Amoako J, Kohler K, Baderhabusha DU, Cáceres E, Nuño-Guzmán CM, Moonesinghe R et al.
(
2026
)
.
Use of pre-operative blood products in abdominal trauma: a planned secondary analysis of the GOAL-trauma study
.
EClinicalMedicine
vol.
93
,
Kalimouttou A, Perkins Z, Gauss T
(
2026
)
.
Artificial intelligence-driven triage and decision-making in trauma systems/settings
.
Current Opinion in Anaesthesiology
vol.
39
,
(
2
)
129
-
135
.
Avest ET, Perkins ZB, Pallavicini P
(
2025
)
.
Pre‐hospital central venous access for major trauma: a reply
.
Anaesthesia
vol.
81
,
(
6
)
899
-
900
.
ter Avest E, Kocierz L, Alvarez C, Hurst T, Ballard D, Lockey DJ, Christian MD, Perkins ZB
(
2025
)
.
Improving decision-making for prehospital Resuscitative Thoracotomy in traumatic cardiac arrest: a data-driven approach
.
Critical Care
vol.
29
,
(
1
)
Edmiston T, Bath MF, Caceres E, Nuño-Guzmán CM, Baderhabusha DU, Khajanchi M, Amoako J, Kohler K et al.
(
2025
)
.
Variation in global trauma care: a survey of 187 hospitals across 51 countries
.
BMJ Global Health
vol.
10
,
(
11
)
Bath MF, Amoako J, Kohler K, Hashi AS, Zhang Z, Baderhabusha DU, Cáceres E, Nuño-Guzmán CM et al.
(
2025
)
.
Global variation in patient factors, interventions, and postoperative outcomes for those undergoing trauma laparotomy: an international, prospective, observational cohort study
.
The Lancet Global Health
vol.
13
,
(
11
)
e1837
-
e1848
.
Pallavicini P, Carenzo L, Adams R, Bird F, Davenport R, Greenhalgh R, Wood AE, Gallagher J et al.
(
2025
)
.
An observational study of pre‐hospital central venous access for patients with haemorrhagic shock due to major trauma
.
Anaesthesia
vol.
81
,
(
1
)
83
-
91
.
Simmons C, Lendrum R, Perkins Z, Grier G, Marsden M
(
2025
)
.
A scoping review of cognitive load assessment tools suitable for clinicians performing REBOA
.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
vol.
33
,
(
1
)
Marsden MER, Perkins ZB, Pisirir E, Marsh W, Kyrimi E, Rossetto A, Lyon RL, Weaver A et al.
(
2025
)
.
Early clinical evaluation of a machine-learning system for risk prediction of trauma-induced coagulopathy in the prehospital setting
.
Emergency Medicine Journal
vol.
42
,
(
10
)
654
-
661
.
Kyrimi E, McLachlan S, Wohlgemut JM, Perkins ZB, Lagnado DA, Marsh W
(
2025
)
.
Explainable AI: definition and attributes of a good explanation for health AI
.
AI and Ethics
vol.
5
,
(
4
)
3883
-
3896
.
Perkins ZB, Greenhalgh R, Avest ET, Aziz S, Whitehouse A, Read S, Foster L, Chege F et al.
(
2025
)
.
Prehospital Resuscitative Thoracotomy for Traumatic Cardiac Arrest
.
JAMA Surgery
vol.
160
,
(
4
)
432
-
440
.
Marsden M, Lendrum R, Perkins Z, Davenport RA
(
2025
)
.
REBOA for remote damage control resuscitation and the race against time
.
Current Opinion in Anaesthesiology
vol.
38
,
(
2
)
100
-
106
.
Carenzo L, Ter Avest E, Tucker H, Glasheen J, Hughes M, Perkins Z, Lockey D, Price J et al.
(
2025
)
.
Air Transport Medicine: From the Field
.
Air Medical Journal
vol.
44
,
(
2
)
128
-
130
.
Sheridan B, Perkins Z
(
2025
)
.
Maintenance of prehospital anaesthesia in trauma patients: inconsistencies and variability in practice
.
BJA Open
vol.
13
,
Weegenaar C, Perkins Z, Lockey D
(
2024
)
.
Pre-hospital management of traumatic cardiac arrest 2024 position statement: Faculty of Prehospital Care, Royal College of Surgeons of Edinburgh
.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
vol.
32
,
(
1
)
Alptekin C, Wohlgemut JM, Perkins ZB, Marsh W, Tai NRM, Yet B
(
2024
)
.
Presenting predictions and performance of probabilistic models for clinical decision support in trauma care
.
International Journal of Medical Informatics
vol.
194
,
Wohlgemut JM, Pisirir E, Stoner RS, Perkins ZB, Marsh W, Tai NRM, Kyrimi E
(
2024
)
.
A scoping review, novel taxonomy and catalogue of implementation frameworks for clinical decision support systems
.
BMC Medical Informatics and Decision Making
vol.
24
,
(
1
)
Simmons C, Marsden M, Sadek S, Greenhalgh R
(
2024
)
.
2995 Assessment of cognitive load in clinicians performing pre-hospital REBOA: development and validation of a novel prehospital assessment tool
.
Conference:
RCEM Annual Scientific Conference 2024 Abstractsa8
-
a8
.
Carenzo L, Calgaro G, Rehn M, Perkins Z, Qasim ZA, Gamberini L, ter Avest E
(
2024
)
.
Contemporary management of traumatic cardiac arrest and peri-arrest states: a narrative review
.
Journal of Anesthesia, Analgesia and Critical Care
vol.
4
,
(
1
)
Lendrum RA, Perkins Z, Marsden M, Cochran C, Davenport R, Chege F, Fitzpatrick-Swallow V, Greenhalgh R et al.
(
2024
)
.
Prehospital Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Exsanguinating Subdiaphragmatic Hemorrhage
.
JAMA Surgery
vol.
159
,
(
9
)
998
-
1007
.
Kyrimi E, McLachlan S, Wohlgemut JM, Perkins ZB, Lagnado DA, Marsh W, Group TEE
(
2024
)
.
Explainable AI: Definition and attributes of a good explanation for health AI
.
Pelly T, Hwang R, Nirmalan P, Perkins Z
(
2024
)
.
Inguinal and femoral hernias
.
The BMJ
vol.
386
,
Wohlgemut JM, Pisirir E, Stoner RS, Kyrimi E, Yet B, Marsh W, Perkins ZB, Tai NRM
(
2024
)
.
Bayesian networks may allow better performance and usability than logistic regression
.
Critical Care
vol.
28
,
(
1
)
Oakley W, Tandle S, Perkins Z
(
2024
)
.
Predicting blood transfusion following traumatic injury using machine learning models: A systematic review and narrative synthesis
.
Journal of Trauma and Acute Care Surgery
vol.
97
,
(
4
)
651
-
659
.
Bath MF, Kohler K, Hobbs L, Smith BG, Clark DJ, Kwizera A, Perkins Z, Marsden M et al.
(
2024
)
.
Evaluating patient factors, operative management and postoperative outcomes in trauma laparotomy patients worldwide: a protocol for a global observational multicentre trauma study
.
BMJ Open
vol.
14
,
(
4
)
Bath MF, Schloer J, Strobel J, Rea W, Lefering R, Maegele M, De’Ath H, Perkins ZB
(
2024
)
.
Trends in pre-hospital volume resuscitation of blunt trauma patients: a 15-year analysis of the British (TARN) and German (TraumaRegister DGU®) National Registries
.
Critical Care
vol.
28
,
(
1
)
Mahdi S, Stoner R, Wyatt J, De'Ath H, Perkins Z
(
2024
)
.
Prevalence of chronic pain after severe lower limb injury (SLLI): A systematic review and meta-analysis
.
Injury
vol.
55
,
(
6
)
Naumann DN, Bhangu A, Brooks A, Martin M, Cotton BA, Khan M, Midwinter MJ, Pearce L et al.
(
2024
)
.
Novel Textbook Outcomes following emergency laparotomy: Delphi exercise
.
BJS Open
vol.
8
,
(
1
)
Wohlgemut JM, Pisirir E, Stoner RS, Kyrimi E, Christian M, Hurst T, Marsh W, Perkins ZB et al.
(
2024
)
.
Identification of major hemorrhage in trauma patients in the prehospital setting: diagnostic accuracy and impact on outcome
.
Trauma Surgery & Acute Care Open
vol.
9
,
(
1
)
Naumann DN, Bhangu A, Brooks A, Martin M, Cotton BA, Khan M, Midwinter MJ, Pearce L et al.
(
2024
)
.
Novel Textbook Outcomes following emergency laparotomy: Delphi exercise
.
BJS Open
vol.
8
,
(
1
)
Kyrimi E, Stoner RS, Perkins ZB, Pisirir E, Wohlgemut JM, Marsh W, Tai NRM
(
2023
)
.
Updating and recalibrating causal probabilistic models on a new target population
.
Journal of Biomedical Informatics
vol.
149
,
Durrands TH, Murphy M, Wohlgemut JM
(
2023
)
.
Diagnostic accuracy of clinical examination for identification of life-threatening torsos injuries: a meta-analysis
.
British Journal of Surgery
vol.
110
,
(
12
)
1885
-
1886
.
Gauss T, Perkins Z, Tjardes T
(
2023
)
.
Current knowledge and availability of machine learning across the spectrum of trauma science
.
Current Opinion in Critical Care
vol.
29
,
(
6
)
713
-
721
.
Tandle S, Wohlgemut JM, Marsden MER, Pisirir E, Kyrimi E, Stoner RS, Marsh W, Perkins ZB et al.
(
2023
)
.
Enhancing the clinical relevance of haemorrhage prediction models in trauma
.
Military Medical Research
vol.
10
,
(
1
)
Almuwallad A, Cole E, Rossetto A, Brohi K, Perkins Z, Davenport R
(
2023
)
.
Nationwide analysis of prehospital tranexamic acid for trauma demonstrates systematic bias in adherence to treatment guidelines: a retrospective cohort study
.
International Journal of Surgery
vol.
109
,
(
12
)
3796
-
3803
.
Marsden MER, Kellett S, Bagga R, Lyon RL, Gillies K
(
2023
)
.
Understanding pre-hospital blood transfusion decision-making for injured patients: an interview study
.
Emergency Medicine Journal
vol.
40
,
(
11
)
777
-
784
.
Ramaraj P, Al-Buluchi T, Al-Shaqsi S, Al-Kashmiri A, Perkins ZB, De'Ath HD
(
2023
)
.
Epidemiology of traumatically injured Yemeni civilians treated at the Omani National Trauma Centre over a 2-year period: a retrospective cohort study
.
BMJ Military Health
vol.
171
,
(
1
)
19
-
25
.
Wohlgemut J, McMullen H, Marsden M, Marsh W, Perkins Z, Tai N
(
2023
)
.
FTP1.7 Critical decision analysis of pre-hospital major haemorrhage protocol activation
.
British Journal of Surgery
vol.
110
,
(
Supplement_6
)
Wohlgemut JM, Pisirir E, Kyrimi E, Stoner RS, Marsh W, Perkins ZB, Tai NRM
(
2023
)
.
Methods used to evaluate usability of mobile clinical decision support systems for healthcare emergencies: a systematic review and qualitative synthesis
.
JAMIA Open
vol.
6
,
(
3
)
Pisirir E, Wohlgemut JM, Kyrimi E, Stoner RS, Perkins ZB, Tai NRM, Marsh DWR
(
2023
)
.
A Process for Evaluating Explanations for Transparent and Trustworthy AI Prediction Models
.
Conference:
2023 IEEE 11th International Conference on Healthcare Informatics (ICHI)
vol.
00
,
388
-
397
.
Wohlgemut JM, Marsden MER, Stoner RS, Pisirir E, Kyrimi E, Grier G, Christian M, Hurst T et al.
(
2023
)
.
Diagnostic accuracy of clinical examination to identify life- and limb-threatening injuries in trauma patients
.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
vol.
31
,
(
1
)
Walters S, Cuthbert R, Ward J, Arshad H, Culpan P, Perkins Z, Tai N, Bates P
(
2023
)
.
Causes and associations with mortality in patients with pelvic ring injuries with haemorrhagic shock
.
European Journal of Orthopaedic Surgery & Traumatology
vol.
33
,
(
7
)
2971
-
2979
.
Marsden M, Perkins Z, Marsh W, Christian M, Lyon R, Davenport R, Tai N
(
2022
)
.
3* Evaluation of an Artificial Intelligence (AI) system to augment clinical risk prediction of Trauma Induced Coagulopathy in the pre-hospital setting: a prospective observational study
.
BMJ Military Health
vol.
168
,
(
5
)
e1.3
-
e1e1
.
Vasey B, Campbell B, Clifton DA, Collins GS, Denaxas S, Denniston AK, Faes L, Geerts B et al.
(
2022
)
.
Publisher Correction: Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI
.
Nature Medicine
vol.
28
,
(
10
)
2218
-
2218
.
Perkins ZB, Kersey AJ, White JM, Lauria AL, Propper BW, Tai NRM, Rasmussen TE
(
2022
)
.
Impact of Ischemia Duration on Lower Limb Salvage in Combat Casualties
.
Annals of Surgery
vol.
276
,
(
3
)
532
-
538
.
ter Avest E, Carenzo L, Lendrum RA, Christian MD, Lyon RM, Coniglio C, Rehn M, Lockey DJ et al.
(
2022
)
.
Advanced interventions in the pre-hospital resuscitation of patients with non-compressible haemorrhage after penetrating injuries
.
Critical Care
vol.
26
,
(
1
)
Vasey B, Nagendran M, Campbell B, Clifton DA, Collins GS, Denaxas S, Denniston AK, Faes L et al.
(
2022
)
.
Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI
.
The BMJ
vol.
377
,
Vasey B, Nagendran M, Campbell B, Clifton DA, Collins GS, Denniston AK, Faes L, Geerts B et al.
(
2022
)
.
Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI
.
Nature Medicine
vol.
28
,
(
5
)
924
-
933
.
Marsden M, Perkins Z, Marsh W, Christian M, Lyon R, Davenport R, Tai N
(
2022
)
.
92 Evaluation of an Artificial Intelligence (AI) System to Augment Clinical Risk Prediction of Trauma Induced Coagulopathy: A Prospective Observational Study
.
British Journal of Surgery
vol.
109
,
(
Supplement_1
)
Kyrimi E, Mossadegh S, Marsden ME, Fenton N, Perkins Z, Tai N, Marsh W
(
2022
)
.
Capturing the Progression of Acute Conditions and the Dynamics of Clinical Decision-Making Using Bayesian Networks
.
Wohlgemut JM, Kyrimi E, Stoner RS, Pisirir E, Marsh W, Perkins ZB, Tai NRM
(
2021
)
.
The outcome of a prediction algorithm should be a true patient state rather than an available surrogate
.
Journal of Vascular Surgery
vol.
75
,
(
4
)
1495
-
1496
.
Chana M, Perkins Z, Lendrum R, Sadek S
(
2021
)
.
A Practical Approach to Introducing Pre-Hospital Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), the Problems Encountered and Lessons Learned
.
Journal of Endovascular Resuscitation and Trauma Management
vol.
5
,
(
2
)
88
-
95
.
Marsden MER, Vulliamy PED, Carden R, Naumann DN, Davenport RA, Collaborative TRAI, Nnajiuba HO, Perkins Z et al.
(
2021
)
.
Trauma Laparotomy in the UK: A Prospective National Service Evaluation
.
Journal of the American College of Surgeons
vol.
233
,
(
3
)
383
-
394.e1
.
Almuwallad A, Cole E, Ross J, Perkins Z, Davenport R
(
2021
)
.
The impact of prehospital TXA on mortality among bleeding trauma patients: A systematic review and meta-analysis
.
Journal of Trauma and Acute Care Surgery
vol.
90
,
(
5
)
901
-
907
.
Singleton BN, Morris FK, Yet B, Buggy DJ, Perkins ZB
(
2021
)
.
Effectiveness of intubation devices in patients with cervical spine immobilisation: a systematic review and network meta-analysis
.
British Journal of Anaesthesia
vol.
126
,
(
5
)
1055
-
1066
.
Perkins ZB, Yet B, Sharrock A, Rickard R, Marsh W, Rasmussen TE, Tai NRM
(
2020
)
.
Predicting the Outcome of Limb Revascularization in Patients With Lower-extremity Arterial Trauma: Development and External Validation of a Supervised Machine-learning Algorithm to Support Surgical Decisions
.
Annals of Surgery
vol.
272
,
(
4
)
564
-
572
.
Kanchustambam SRV, Sharma A, Perkins Z, Patel A
(
2020
)
.
Diagnostic performance of EUS in non-jaundiced patients with an incidental finding of double duct sign on cross-sectional imaging: A systematic review and meta-analysis
.
Pancreatology
vol.
20
,
(
5
)
992
-
996
.
Tyler JA, Perkins Z, De’Ath HD
(
2020
)
.
Intraosseous access in the resuscitation of trauma patients: a literature review
.
European Journal of Trauma and Emergency Surgery
vol.
47
,
(
1
)
47
-
55
.
Hughes M, Perkins Z
(
2020
)
.
Outcomes following resuscitative thoracotomy for abdominal exsanguination, a systematic review
.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
vol.
28
,
(
1
)
Perkins ZB, Yet B, Marsden M, Glasgow S, Marsh W, Davenport R, Brohi K, Tai NRM
(
2020
)
.
Early Identification of Trauma-induced Coagulopathy
.
Annals of Surgery
vol.
274
,
(
6
)
e1119
-
e1128
.
Perkins ZB, Haines RW, Prowle JR
(
2019
)
.
Trauma-associated acute kidney injury
.
Current Opinion in Critical Care
vol.
25
,
(
6
)
565
-
572
.
Lendrum R, Perkins Z, Chana M, Marsden M, Davenport R, Grier G, Sadek S, Davies G
(
2019
)
.
Reply to: Prehospital REBOA: Time to clearly define the relevant indications
.
Resuscitation
vol.
142
,
191
-
192
.
Sharrock AE, Tai N, Perkins Z, White JM, Remick KN, Rickard RF, Rasmussen TE
(
2019
)
.
Management and outcome of 597 wartime penetrating lower extremity arterial injuries from an international military cohort
.
Journal of Vascular Surgery
vol.
70
,
(
1
)
224
-
232
.
Perkins ZB, Captur G, Bird R, Gleeson L, Singer B, O’Brien B
(
2019
)
.
Trauma induced acute kidney injury
.
PLOS ONE
vol.
14
,
(
1
)
Lendrum R, Perkins Z, Chana M, Marsden M, Davenport R, Grier G, Sadek S, Davies G
(
2018
)
.
Pre-hospital Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) for exsanguinating pelvic haemorrhage
.
Resuscitation
vol.
135
,
6
-
13
.
Glasgow SM, Perkins ZB, Tai NRM, Brohi K, Vasilakis C
(
2018
)
.
Development of a discrete event simulation model for evaluating strategies of red blood cell provision following mass casualty events
.
European Journal of Operational Research
vol.
270
,
(
1
)
362
-
374
.
Swinton P, Corfield AR, Moultrie C, Percival D, Proctor J, Sinclair N, Perkins ZB
(
2018
)
.
Impact of drug and equipment preparation on pre-hospital emergency Anaesthesia (PHEA) procedural time, error rate and cognitive load
.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
vol.
26
,
(
1
)
Sharrock AM, Perkins Z, Tai NRM, White JM, Remick KN, Rickard RF, Rasmussen TE
(
2018
)
.
Management and Outcome of 597 Wartime Lower Extremity Arterial Injuries: Results From an International Military Cohort
.
Journal of Vascular Surgery
.
vol.
68
,
Lamhaut L, Qasim Z, Hutin A, Dagron C, Orsini J-P, Haegel A, Perkins Z, Pirracchio R et al.
(
2018
)
.
First description of successful use of zone 1 resuscitative endovascular balloon occlusion of the aorta in the prehospital setting
.
Resuscitation
vol.
133
,
e1
-
e2
.
Perkins ZB, Yet B, Glasgow S, Marsh DWR, Tai NRM, Rasmussen TE
(
2018
)
.
Long-term, patient-centered outcomes of lower-extremity vascular trauma
.
Journal of Trauma and Acute Care Surgery
vol.
85
,
(
1S
)
s104
-
s111
.
Burgess MR, Crewdson K, Lockey DJ, Perkins ZB
(
2018
)
.
Prehospital emergency anaesthesia: an updated survey of UK practice with emphasis on the role of standardisation and checklists
.
Emergency Medicine Journal
vol.
35
,
(
9
)
Peacock J, Perkins Z
(
2017
)
.
Change in bowel habit, abdominal pain, and a palpable abdominal mass in a 58‐year‐old female
.
Clinical Case Reports
vol.
5
,
(
12
)
2155
-
2157
.
Crichton JCI, Naidoo K, Brundage SI, Perkins Z
(
2017
)
.
The role of splenic angioembolization as an adjunct to nonoperative management of blunt splenic injuries
.
Journal of Trauma and Acute Care Surgery
vol.
83
,
(
5
)
934
-
943
.
Fevang E, Perkins Z, Lockey D, Jeppesen E, Lossius HM
(
2017
)
.
A systematic review and meta-analysis comparing mortality in pre-hospital tracheal intubation to emergency department intubation in trauma patients
.
Critical Care
vol.
21
,
(
1
)
Perkins ZB, Yet B, Glasgow S, Marsh W, Rasmussen TE, Tai NRM
(
2017
)
.
Predicting limb viability following lower extremity vascular trauma
.
BRITISH JOURNAL OF SURGERY
.
vol.
104
,
7
-
7
.
Perkins ZB, Lendrum RA, Brohi K
(
2016
)
.
Resuscitative endovascular balloon occlusion of the aorta
.
vol.
22
,
is.
6
,
pp.
563
-
571
.
Wolters Kluwer
Perkins ZB, Lendrum RA, Brohi K
(
2016
)
.
Resuscitative endovascular balloon occlusion of the aorta: promise, practice, and progress?
.
Curr Opin Crit Care
vol.
22
,
(
6
)
563
-
571
.
Mossadegh S, Yet B, Perkins Z, Marsh W, Tai N
(
2016
)
.
Predictive Accuracy of a Civilian Bayesian Network Trauma Tool in a Military Cohort and Applicability to Trauma Performance Improvement
.
BRITISH JOURNAL OF SURGERY
vol.
103
,
96
-
96
.
Glasgow S, Vasilakis C, Perkins Z, Brundage S, Tai N, Brohi K
(
2016
)
.
Managing the surge in demand for blood following mass casualty events
.
Journal of Trauma and Acute Care Surgery
vol.
81
,
(
1
)
50
-
57
.
Sadek S, Lockey DJ, Lendrum RA, Perkins Z, Price J, Davies GE
(
2016
)
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