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Research

Publications: PROF Michelle West

Campos-León K, Ferguson J, Günther T, Wood CD, Wingett SW, Pekel S, Varghese CS, Jones LS et al. ( 2025 ) . Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions . PLOS Pathogens vol. 21 , ( 1 )
Bryce-Sharron N, Nasiri M, Powell T, West MJ, Crickmore N ( 2024 ) . A Shared Receptor Suggests a Common Ancestry between an Insecticidal Bacillus thuringiensis Cry Protein and an Anti-Cancer Parasporin . Biomolecules vol. 14 , ( 7 )
Khasnis S, Veenstra H, McClellan MJ, Ojeniyi O, Wood CD, West MJ ( 2022 ) . Regulation of B cell receptor signalling by Epstein–Barr virus nuclear antigens . Biochemical Journal vol. 479 , ( 23 ) 2395 - 2417 .
Agnarelli A, Mitchell S, Caalim G, Wood CD, Milton‐Harris L, Chevassut T, West MJ, Mancini EJ ( 2022 ) . Dissecting the impact of bromodomain inhibitors on the Interferon Regulatory Factor 4‐MYC oncogenic axis in multiple myeloma . Hematological Oncology vol. 40 , ( 3 ) 417 - 429 .
Souissi W, Alistair T, Domanska B, Fortea E, West MJ, Schwartz J-L, Crickmore N ( 2022 ) . Probing the Mechanism of Action of Cry41Aa on HepG2 through the Establishment of a Resistant Subline . Toxins vol. 14 , ( 5 )
Souissi W, Kaloki A, Etherington S, Domanska B, West MJ, Crickmore N ( 2019 ) . Differential proteolytic activation of the Bacillus thuringiensis Cry41Aa parasporin modulates its anticancer effect . Biochemical Journal vol. 476 , ( 24 ) 3805 - 3816 .
Ponnusamy R, Khatri R, Correia PB, Wood CD, Mancini EJ, Farrell PJ, West MJ ( 2019 ) . Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity . PLOS Pathogens vol. 15 , ( 7 )
Domanska B, Fortea E, West MJ, Schwartz J-L, Crickmore N ( 2019 ) . The role of membrane-bound metal ions in toxicity of a human cancer cell-active pore-forming toxin Cry41Aa from Bacillus thuringiensis . Toxicon vol. 167 , 123 - 133 .
Pentland I, Campos-León K, Cotic M, Davies K-J, Wood CD, Groves IJ, Burley M, Coleman N et al. ( 2018 ) . Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription . PLOS Biology vol. 16 , ( 10 )
Wood CD, Carvell T, Gunnell A, Ojeniyi OO, Osborne C, West MJ ( 2018 ) . Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B Cells . Journal of Virology vol. 92 , ( 19 ) 10.1128/jvi.00716 - 10.1128/jvi.00718 .
Brocard M, Khasnis S, Wood CD, Shannon-Lowe C, West MJ ( 2018 ) . Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32 . Nucleic Acids Research vol. 46 , ( 7 )
Wood CD, Veenstra H, Khasnis S, Gunnell A, Webb HM, Shannon-Lowe C, Andrews S, Osborne CS et al. ( 2016 ) . MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs . eLife vol. 5 ,
Maunders MJ, Petti L, Rowe M ( 1994 ) . Precipitation of the Epstein—Barr virus protein EBNA 2 by an EBNA 3c-specific monoclonal antibody . Journal of General Virology vol. 75 , ( 4 ) 769 - 778 .