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Research

Publications: DR Amit Roshan

( 2026 ) . Long-term outcomes of cutaneous basal cell and squamous cell carcinomas with < 1 mm close primary surgical excision margins managed in a UK tertiary centre multidisciplinary team . EJC Skin Cancer vol. 4 ,
( 2025 ) . Abstract 3775: Liquid biopsy for therapy planning in clinically N0 head and neck cancer (LiC0HN) - A personalized cell-free tumor DNA analysis for patients with HNSCC . Cancer Research vol. 85 , ( 8_Supplement_1 ) 3775 - 3775 .
Roshan A, Talukdar FR, An A, Ditter E-J, Zhou Z, Mennea PD, Wu L, Neofytou MC et al. ( 2025 ) . Abstract 4550: Dried blood sot sampling as a minimally invasive and accessible method for investigating circulating tumor DNA in diverse cancer settings . Cancer Research vol. 85 , ( 8_Supplement_1 ) 4550 - 4550 .
Cheng Z, McDonald S, Thomas H, Zhou Z, Mennea P, Haichao wang, Shcherbo D, Zhang C et al. ( 2025 ) . Abstract 4631: Deciphering immunotherapy response variability and immune-related toxicities through longitudinal multimodal ctDNA analysis in advanced melanoma . Cancer Research vol. 85 , ( 8_Supplement_1 ) 4631 - 4631 .
( 2025 ) . Reporting of molecular test results from cell-free DNA analyses: expert consensus recommendations from the 2023 European Liquid Biopsy Society ctDNA Workshop . EBioMedicine vol. 114 ,
( 2025 ) . Physics-based skin color bias correction for equitable photoacoustic imaging (Conference Presentation) . Conference: Photons Plus Ultrasound: Imaging and Sensing 2025
( 2025 ) . Abstract B064: Utility of ctDNA assessment after six weeks of immunotherapy to predict radiological response in advanced esophageal cancer . Cancer Immunology Research vol. 13 , ( 2_Supplement ) b064 - b064 .
( 2025 ) . A-247 Long-term local recurrence and further primary skin cancers in cutaneous basal cell carcinoma with involved or close primary excision margins . EJC Skin Cancer vol. 3 ,
( 2025 ) . A-534 Long-term recurrence and disease specific mortality in cutaneous squamous cell carcinoma with involved or close primary excision margins . EJC Skin Cancer vol. 3 ,
( 2025 ) . A-630 Detecting circulating tumor DNA in archived whole blood samples in patients undergoing treatment for primary cutaneous melanoma . EJC Skin Cancer vol. 3 ,
( 2025 ) . Does the interval between melanoma diagnosis and surgery have an impact on outcomes? A systematic review and meta-analysis . EJC Skin Cancer vol. 3 ,
( 2025 ) . Sentinel lymph node biopsy for cutaneous melanoma performed within 6 weeks of diagnostic excision compared to those performed at longer time intervals in a UK cohort . EJC Skin Cancer vol. 3 ,
( 2024 ) . Systematic review of risk prediction tools for primary cutaneous melanoma outcomes and validation of sentinel lymph node positivity prediction in a UK tertiary cohort . BJC Reports vol. 2 , ( 1 )
( 2024 ) . Next day sentinel node biopsy for melanoma after lymphoscintigraphy using 99mTc-labelled nanocolloid does not adversely affect long-term outcomes . Annals of Nuclear Medicine vol. 39 , ( 1 ) 77 - 85 .
( 2024 ) . HERD: A multi-centre prospective cohort study to facilitate early detection of relapse in radically treated, high risk head and neck squamous cell carcinoma . Journal of Clinical Oncology vol. 42 , ( 16_suppl ) tps6128 - tps6128 .
( 2024 ) . Incidental Breast Cancer Diagnosis From Lymphoscintography Using 99mTc-Labeled Nanocolloid for Cutaneous Melanoma of the Upper Arm . Clinical Nuclear Medicine vol. 49 , ( 8 ) 748 - 749 .
( 2024 ) . ASO Visual Abstract: Robot-Assisted Pelvic Dissection for Enlarged Lymph Nodes in Melanoma Improves Recovery with Equivalent Oncological Outcomes to Open Pelvic Dissection . Annals of Surgical Oncology vol. 31 , ( 4 ) 2747 - 2748 .
( 2024 ) . Robot-Assisted Pelvic Dissection for Enlarged Lymph Nodes in Melanoma Improves Recovery with Equivalent Oncological Outcomes to Open Pelvic Dissection . Annals of Surgical Oncology vol. 31 , ( 4 ) 2727 - 2736 .
( 2024 ) . A-300 Lymph Node Operative Experience in the UK – What’s Changed? . EJC Skin Cancer vol. 2 ,
( 2024 ) . A-378 Does the interval between melanoma diagnosis and surgery have an impact on outcomes? A systematic review and meta-analysis . EJC Skin Cancer vol. 2 ,
( 2024 ) . A-393 Assessment of performance in clinical risk prediction tools for cutaneous melanoma in the UK population . EJC Skin Cancer vol. 2 ,
( 2024 ) . A-407 Time interval between Sentinel Lymph Node Biopsy and Excision of Primary Melanoma does not impact long term outcomes in a large UK cohort . EJC Skin Cancer vol. 2 ,
( 2023 ) . 235TiP Hamlet.rt Trans: Prospective single-centre translational study evaluating liquid biomarkers of radiation response . Annals of Oncology vol. 34 ,
( 2023 ) . Complex Lymphatic Drainage in Head and Neck Cutaneous Melanoma and SLNB Outcomes—Reply . JAMA Otolaryngology - Head & Neck Surgery vol. 149 , ( 9 ) 854 - 854 .
( 2023 ) . Association of Complex Lymphatic Drainage in Head and Neck Cutaneous Melanoma With Sentinel Lymph Node Biopsy Outcomes . JAMA Otolaryngology - Head & Neck Surgery . vol. 149 , 416 - 423 .
( 2023 ) . 198 Hamlet.rt Trans: a prospective single-centre translational sub-study evaluation of liquid biomarkers of radiation response . Lung Cancer vol. 178 ,
( 2023 ) . Robot-assisted pelvic node dissection has similar operative and melanoma outcomes to open pelvic node dissection with shorter hospital stays . European Journal of Surgical Oncology vol. 49 , ( 1 ) e16 - e17 .
( 2021 ) . A retrospective analysis of rates of allergic reaction to Patent V blue dye used in sentinel lymph node biopsies for melanoma . Journal of Plastic Reconstructive & Aesthetic Surgery vol. 75 , ( 2 ) 893 - 939 .
( 2021 ) . Lymph node dissections in cutaneous malignancy: Where are we now? A review of 10 years’ experience at a tertiary centre . Journal of Plastic Reconstructive & Aesthetic Surgery vol. 74 , ( 11 ) 2993 - 2998 .
( 2021 ) . A new clinical presentation: breast implant pneumocapsule and pneumothorax following penetrating chest wall trauma . Annals of The Royal College of Surgeons of England vol. 103 , ( 3 ) e98 - e100 .
( 2021 ) . Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site . Cancer Discovery vol. 11 , ( 2 ) 340 - 361 .
( 2020 ) . Response to letter regarding: Poorly differentiated cutaneous squamous cell carcinomas have high incomplete excision rates with UK minimum recommended pre-determined surgical margins . Journal of Plastic Reconstructive & Aesthetic Surgery vol. 74 , ( 4 ) 890 - 930 .
( 2019 ) . CORR Insights®: Can Sural Fasciocutaneous Flaps Be Effective in Patients Older Than 65? . Clinical Orthopaedics and Related Research vol. 478 , ( 4 ) 739 - 740 .
( 2019 ) . Poorly differentiated cutaneous squamous cell carcinomas have high incomplete excision rates with UK minimum recommended pre-determined surgical margins . Journal of Plastic Reconstructive & Aesthetic Surgery vol. 73 , ( 1 ) 43 - 52 .
( 2015 ) . Human keratinocytes have two interconvertible modes of proliferation . Nature Cell Biology vol. 18 , ( 2 ) 145 - 156 .
( 2015 ) . High burden and pervasive positive selection of somatic mutations in normal human skin . Science vol. 348 , ( 6237 ) 880 - 886 .
( 2014 ) . Exact, time-independent estimation of clone size distributions in normal and mutated cells . Journal of The Royal Society Interface vol. 11 , ( 99 )
( 2014 ) . Abstract 145 . Plastic & Reconstructive Surgery vol. 133 , ( 3S ) 160 - 161 .
( 2013 ) . An Exact, Time-Independent Approach to Clone Size Distributions in Normal and Mutated Cells .
( 2013 ) . Outpatient taping in the treatment of idiopathic congenital talipes equinovarus . The Bone & Joint Journal vol. 95-B , ( 2 ) 271 - 278 .
( 2012 ) . Act your age: Tuning cell behavior to tissue requirements in interfollicular epidermis . Seminars in Cell and Developmental Biology vol. 23 , ( 8 ) 884 - 889 .
( 2012 ) . Chronic low dose UV exposure and p53 mutation: Tilting the odds in early epidermal preneoplasia? . International Journal of Radiation Biology vol. 88 , ( 10 ) 682 - 687 .
( 2012 ) . A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium . Science vol. 337 , ( 6098 ) 1091 - 1093 .
( 2012 ) . Lessons for Adult Fingertip Regeneration: Glimpses From Basic Research . The Journal Of Hand Surgery vol. 37 , ( 6 ) 1287 - 1290 .
( 2010 ) . 2-Week wait referrals in suspected skin cancer: Does an instructional module for general practitioners improve diagnostic accuracy? . The Surgeon vol. 8 , ( 5 ) 247 - 251 .
( 2009 ) . Emergency and early management of burns and scalds . The BMJ vol. 338 , ( apr08 1 )
( 2009 ) . Pedicled gracilis myocutaneous flap for treatment of recalcitrant hidradenitis suppurativa of the groin and perineum . Journal of Wound Care vol. 18 , ( 3 ) 111 - 112 .
( 2008 ) . Role of information available over the internet: what are the parents of children undergoing tonsillectomy likely to find? . Annals of The Royal College of Surgeons of England vol. 90 , ( 7 ) 601 - 605 .
( 2008 ) . Sternal wound dehiscence complicated by macromastia: report of two cases with discussion of literature . Journal of Plastic Reconstructive & Aesthetic Surgery vol. 62 , ( 10 ) e362 - e364 .
( 2008 ) . The Neglected Femoral Neck Fracture in Young Adults: Review of a Challenging Problem . Clinical Medicine & Research vol. 6 , ( 1 ) 33 - 39 .
( 2006 ) . Response to Mace and Stearns . Clinical Otolaryngology vol. 31 , ( 6 ) 556 - 557 .
( 2006 ) . Early Return to Function in Young Adults with Neglected Femoral Neck Fractures . Clinical Orthopaedics and Related Research vol. 447 , ( &NA; ) 152 - 157 .
( 2006 ) . Intra‐operative parathyroid hormone monitoring in secondary hyperparathyroidism: is it useful? . Clinical Otolaryngology vol. 31 , ( 3 ) 198 - 203 .
. A mathematical model of cell-free DNA fragment size reveals cancer-specific fragmentomic patterns .
. The confounding effects of skin colour in photoacoustic imaging .
. Utility of ctDNA assessment after six weeks of immunotherapy to predict radiological response in advanced oesophageal cancer .