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Research

Publications: DR Claire Villette

Villette C, Champion A ( 2025 ) . Development of an In Vitro Bone Metastasis Model Mimicking Cellular Crosstalk in the Bone Microenvironment . Conference: Congress of the European Society Of Biomaterials ( Turin ) from: 11/09/2025 to: 07/09/2025 ,
Gucciardo F, Lebeau A, Pirson S, Buntinx F, Ivanova E, Blacher S, Brouillard P, Deroye J et al. ( 2025 ) . Targeting uPARAP Modifies Lymphatic Vessel Architecture and Attenuates Lymphedema . Circulation vol. 151 , ( 19 ) 1412 - 1429 .
Villette CC, Dupuy N, Brightman FA, Zimmermann A, Lignet F, Zenke FT, Terranova N, Bolleddula J et al. ( 2025 ) . Semi-mechanistic efficacy model for PARP + ATR inhibitors—application to rucaparib and talazoparib in combination with gartisertib in breast cancer PDXs . British Journal of Cancer vol. 132 , ( 5 ) 481 - 491 .
Villette C, Phillips ATM ( 2024 ) . Influence of a change in activity regime on femoral bone architecture and failure behaviour . Plos One
Villette CC, Orrell D, Millen J, Chassagnole C ( 2023 ) . Should personalised dosing have a role in cancer treatment? . Frontiers in Oncology vol. 13 ,
Villette C, Geris L ( 2023 ) . Therapeutic effect of mechanical loading on bone metastasis: an hca modelling framework .
Villette C, Geris L ( 2022 ) . Hybrid cellular automaton representation of the influence of mechanical stimulation on the development of bone metastases .
Hurry C, Villette C, Mistry H, Millen J, Chassagnole C ( 2021 ) . A precision dosing application for patients treated with docetaxel and G-CSF . vol. 81 , is. 13 ,
Villette C, Hurry C, Mistry H, Millen J, Chassagnole C ( 2021 ) . A precision dosing application for prostate cancer patients treated with docetaxel and G-CSF . vol. 39 , is. 15_suppl , pp. e13585 - e13585 . American Society of Clinical Oncology (ASCO)
Castilho M, de Ruijter M, Beirne S, Villette CC, Ito K, Wallace GG, Malda J ( 2020 ) . Multitechnology Biofabrication: A New Approach for the Manufacturing of Functional Tissue Structures? . Trends in Biotechnology vol. 38 , ( 12 ) 1316 - 1328 .
Villette CC, Zhang J, Phillips ATM ( 2019 ) . Influence of femoral external shape on internal architecture and fracture risk . Biomechanics and Modeling in Mechanobiology vol. 19 , ( 4 ) 1251 - 1261 .
Villette C, Mistry H, Ortega FG, Orrell D, Brightman FA, Millen J, Chassagnole C ( 2019 ) . A precision dosing application for prostate cancer chemotherapy . AACR ( Atlanta, US ), Notes: Added to JabRef: 2021-01-15 ,
Ortega F, Orell D, Villette C, Mistry H, Brightman F, Millen J, Chassagnole C ( 2019 ) . Developing a head and neck cancer model to assess the effect of radiotherapy on tumour growth inhibition and regrowth . Notes: Added to JabRef: 2020-07-02 ,
Villette CC, Phillips ATM ( 2018 ) . Rate and age-dependent damage elasticity formulation for efficient hip fracture simulations . Medical Engineering & Physics vol. 61 , ( 1 ) 1 - 12 .
Villette CC, Castilho M, Malda J, Phillips A ( 2018 ) . Computational design optimisation for local control over mechanical properties in heterogeneous scaffolds .
Villette CC, Castilho M, Malda J, Phillips A ( 2018 ) . Heterogeneous design optimisation of tissue engineering scaffolds: in-vitro assessment of a digital design framework .
Villette C ( 2018 ) . Optimised heterogeneous scaffolds for bone tissue engineering: towards tailored mechanical stimulation .
Villette CC, Phillips ATM ( 2017 ) . Microscale poroelastic metamodel for efficient mesoscale bone remodelling simulations . Biomechanics and Modeling in Mechanobiology vol. 16 , ( 6 ) 2077 - 2091 .
Villette C, Castilho M, Malda J, Phillips A ( 2017 ) . Optimisation of heterogeneous bone tissue engineering scaffolds: proof of concept for a digital design tool . vol. 23 ,
Villette C, Castilho M, Malda J, Phillips A ( 2017 ) . Optimised heterogeneous scaffolds for bone tissue engineering: towards tailored bone mechanotransduction .
Villette C, Phillips A ( 2016 ) . Microscale poroelastic metamodel for efficient mesoscale bone remodelling simulations . pp. 2091 - 2091 .
Villette C, Phillips A ( 2016 ) . Surrogate poroelastic microscale representation of bone remodelling to inform an ef?cient structural mesoscale bone adaptation model . vol. 16 , is. 6 , pp. 2077 - 2091 .
Villette CC, Phillips ATM ( 2015 ) . Informing phenomenological structural bone remodelling with a mechanistic poroelastic model . Biomechanics and Modeling in Mechanobiology vol. 15 , ( 1 ) 69 - 82 .
Phillips ATM, Villette CC, Modenese L ( 2015 ) . Femoral bone mesoscale structural architecture prediction using musculoskeletal and finite element modelling . International Biomechanics vol. 2 , ( 1 ) 43 - 61 .
Villette C, Zaharie D, Phillips A ( 2015 ) . Frangible optimised lower limb surrogate for assessing injury caused by underbelly blast . pp. 746 - 747 .
Villette C, Phillips A ( 2015 ) . Rate and age-dependent damage elasticity formulation for efficient hip fracture simulations . vol. 61 , pp. 1 - 12 . Elsevier BV ( Brisbane (AU) ),
Villette C, Modenese L, Phillips A ( 2014 ) . Combined finite element and musculoskeletal predictive structural modelling of the femur: Potential mechanobiology applications . ES ( Barcelona ),
Villette C, Phillips A, Modenese L ( 2014 ) . Combined musculoskeletal and finite element predictive modelling of bone structure and simple fracture analysis .
Villette C, Phillips A ( 2014 ) . Combined musculoskeletal and finite element predictive modelling of bone structure for study of solid blast injury .
Villette C, Phillips A ( 2014 ) . Combined predictive structural finite element and musculoskeletal modelling of bone structure for study of fracture under solid blast condition .
Villette C, Phillips A ( 2014 ) . Towards a patient-specific combined musculoskeletal and finite element model of bone structure .
Prinold JAI, Villette CC, Bull AMJ ( 2013 ) . The influence of extreme speeds on scapula kinematics and the importance of controlling the plane of elevation . Clinical Biomechanics vol. 28 , ( 9-10 ) 973 - 980 .
Villette C, Thibon A, Modenese L, Phillips A ( 2013 ) . Combined Musculoskeletal and Finite Element Modelling of the Femur .