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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Rachel Varughese

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Varughese RS, Pujari D, Hatton E, Dyakova T, Sparks K, Flack S, Dastamani A, Katugampola H et al. ( 2026 ) . Endocrine characteristics in Bardet-Biedl syndrome from a large single-center pediatric multidisciplinary clinic . The Journal of Clinical Endocrinology & Metabolism
Varughese R, Lake L, Kothayan B, Ahmed NS, Aitken K, Bhavsar K, Edwards J, Newsome A et al. ( 2026 ) . Efficacy of 24-weekly vs 12-weekly decapeptyl SR treatment in central precocious puberty: a UK multicentre retrospective cohort study . The Journal of Clinical Endocrinology & Metabolism
Varughese R, Bonomi M, Butler G, Candler T, Cole T, Dattani M, Heger S, Jayasena C et al. ( 2025 ) . Pilot data from the I-HH registry: improving management in hypogonadotropic hypogonadism . Endocrine Abstracts
Varughese RS, Bonomi M, Butler G, Candler T, Cole TJ, Dattani MT, Heger S, Jayasena C et al. ( 2025 ) . SAT-176 Pilot Data Collection From The New I-HH Registry For Surveillance Of Hypogonadotropic Hypogonadism, Implementation Of Best Practice Management And International Standardisation . Journal of the Endocrine Society vol. 9 , ( Supplement_1 )
Castro S, Laurer E, Varughese R, Bryce J, Ahmed F, Rey R, Hogler W, Heger S et al. ( 2024 ) . Towards best practice therapies for patients with gonadotropin deficiency in minipuberty and puberty . Endocrine Abstracts
Alexander EC, Faruqi D, Farquhar R, Unadkat A, Yin KN, Hoskyns R, Varughese R, Howard SR ( 2023 ) . Gonadotropins for pubertal induction in males with hypogonadotropic hypogonadism: systematic review and meta-analysis . European Journal of Endocrinology vol. 190 , ( 1 ) s1 - s11 .
Alexander E, Yin KN, Faruqi D, Farquhar R, Unadkat A, Varughese R, Howard S ( 2023 ) . Systematic review and meta-analysis of spermatogenesis rates after pubertal induction with gonadotropins in males with hypogonadotropic hypogonadism . Endocrine Abstracts
Voysey M, Clemens SAC, Madhi SA, Weckx LY, Folegatti PM, Aley PK, Angus B, Baillie VL et al. ( 2021 ) . Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials . The Lancet vol. 397 , ( 10277 ) 881 - 891 .
Barrett JR, Belij-Rammerstorfer S, Dold C, Ewer KJ, Folegatti PM, Gilbride C, Halkerston R, Hill J et al. ( 2020 ) . Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses . Nature Medicine vol. 27 , ( 2 ) 279 - 288 .
Ewer KJ, Barrett JR, Belij-Rammerstorfer S, Sharpe H, Makinson R, Morter R, Flaxman A, Wright D et al. ( 2020 ) . T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial . Nature Medicine vol. 27 , ( 2 ) 270 - 278 .
Voysey M, Clemens SAC, Madhi SA, Weckx LY, Folegatti PM, Aley PK, Angus B, Baillie VL et al. ( 2020 ) . Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK . The Lancet vol. 397 , ( 10269 ) 99 - 111 .
Ramasamy MN, Minassian AM, Ewer KJ, Flaxman AL, Folegatti PM, Owens DR, Voysey M, Aley PK et al. ( 2020 ) . Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial . The Lancet vol. 396 , ( 10267 ) 1979 - 1993 .
Folegatti PM, Ewer KJ, Aley PK, Angus B, Becker S, Belij-Rammerstorfer S, Bellamy D, Bibi S et al. ( 2020 ) . Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial . The Lancet vol. 396 , ( 10249 ) 467 - 478 .
Varughese R, Ryan F, Makaya T ( 2020 ) . Fifteen-minute consultation: a structured approach to the child with primary amenorrhea . Archives of Disease in Childhood Education & Practice vol. 106 , ( 1 ) 18 - 22 .
Tan E, Varughese R, Semprini R, Montgomery B, Holweg C, Olsson J, Caswell-Smith R, Fingleton J et al. ( 2018 ) . Serum periostin levels in adults of Chinese descent: an observational study . Allergy, Asthma & Clinical Immunology vol. 14 , ( 1 )
Varughese R, Semprini R, Munro C, Fingleton J, Holweg C, Weatherall M, Beasley R, Braithwaite I ( 2018 ) . Serum periostin levels following small bone fractures, long bone fractures and joint replacements: an observational study . Allergy, Asthma & Clinical Immunology vol. 14 , ( 1 )
Semprini R, Shortt N, Ebmeier S, Semprini A, Varughese R, Holweg CTJ, Matthews JG, Fingleton J et al. ( 2018 ) . Change in biomarkers of type-2 inflammation following severe exacerbations of asthma . Thorax vol. 74 , ( 1 ) 95 - 98 .
Ridgeon EE, Bellomo R, Aberegg SK, Sweeney RM, Varughese RS, Landoni G, Young PJ ( 2017 ) . Effect sizes in ongoing randomized controlled critical care trials . Critical Care vol. 21 , ( 1 )
Varughese R, Bandaranayake G, Mathew A ( 2015 ) . Cut by a double edged sword: a self limiting companion to focal seizures . The BMJ vol. 350 , ( apr01 2 )
Varughese RS, Ridgeon E, Mathew A, Sola-Del Valle D ( 2015 ) . A rapidly enlarging swelling of the left orbit . The BMJ vol. 350 , ( feb25 12 )
Varughese R, Frith P ( 2014 ) . Fifteen minutes consultation: a structured approach to the child with a white red reflex . Archives of Disease in Childhood Education & Practice vol. 99 , ( 5 )
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