Publications: DR Vito Mennella

Augière C, Campolina-Silva G, Vijayakumaran A, Medagedara O, Lavoie-Ouellet C, Joly Beauparlant C, Droit A, Barrachina F et al. ( 2024 ) . ARL13B controls male reproductive tract physiology through primary and Motile Cilia . Communications Biology vol. 7 , ( 1 )

Andersen JS, Vijayakumaran A, Godbehere C, Lorentzen E, Mennella V, Schou KB ( 2024 ) . Uncovering structural themes across cilia microtubule inner proteins with implications for human cilia function . Nature Communications vol. 15 , ( 1 )

Mao Y-Q, Seraphim TV, Wan Y, Wu R, Coyaud E, Bin Munim M, Mollica A, Laurent E et al. ( 2024 ) . DPCD is a regulator of R2TP in ciliogenesis initiation through Akt signaling . Cell Reports vol. 43 , ( 2 )

Mennella V ( 2024 ) . Preface . Methods in Molecular Biology vol. 2725 ,

Poch O, Istiqomah I, Quirico E, Beck P, Schmitt B, Theulé P, Faure A, Hily-Blant P et al. ( 2023 ) . Identification of Ammonium Salts on Comet 67P/C-G Surface from Infrared VIRTIS/Rosetta Data Based on Laboratory Experiments. Implications and Perspectives .

Morone N, Martin MG, Goggin P, Czymmek KJ, Mennella V, Gonzalez JL ( 2023 ) . A Novel Sandwich Method for Serial Block Face SEM Imaging of Airway Multiciliated Epithelium . Methods in Molecular Biology vol. 2725 , 121 - 129 .

Vijayakumaran A, Abuammar A, Medagedara O, Narayan K, Mennella V ( 2023 ) . Airway Cells 3D Reconstruction via Manual and Machine-Learning Aided Segmentation of Volume EM Datasets . Methods in Molecular Biology vol. 2725 , 131 - 146 .

Poch O, Istiqomah I, Quirico E, Beck P, Schmitt B, Theulé P, Faure A, Hily-Blant P et al. ( 2023 ) . Identification of Ammonium Salts on Comet 67P/C-G Surface from Infrared VIRTIS/Rosetta Data Based on Laboratory Experiments. Implications and Perspectives . European Conference on Laboratory Astrophysics ECLA2020 , vol. 59 , Springer Nature

Mennella V ( 2023 ) . Structured Illumination Microscopy . Encyclopedia of Cell Biology , Elsevier

Costain G, Liu Z, Mennella V, Radicioni G, Goczi AN, Albulescu A, Walker S, Ngan B et al. ( 2022 ) . Hereditary Mucin Deficiency Caused by Biallelic Loss of Function of MUC5B . American Journal of Respiratory and Critical Care Medicine vol. 205 , ( 7 ) 761 - 768 .

Mennella V, Liu Z ( 2022 ) . Nanometer-Scale Molecular Mapping by Super-resolution Fluorescence Microscopy . Fluorescent Microscopy , vol. 2440 , Springer Nature

Mennella V, Jackson CL, Driessens C, Horton KL, Lucas JS ( 2022 ) . Primary Ciliary Dyskinesia . Encyclopedia of Respiratory Medicine , Elsevier

Jackson CL, Blume C, Spalluto CM, Mc Cormick CJ, Davies DE, Lucas JS, Mennella V, Wheway G ( 2021 ) . A novel short isoform of ACE2 is expressed in ciliated airway epithelium and is induced by interferon and rhinovirus infection but not SARS-COV-2; implications for COVID-19 interferon treatment . Conference: Airway cell biology and immunopathology

Wheway G, Thomas NS, Carroll M, Coles J, Doherty R, Goggin P, Green B, Harris A et al. ( 2021 ) . Whole genome sequencing in the diagnosis of primary ciliary dyskinesia . BMC Medical Genomics vol. 14 , ( 1 )

Blume C, Jackson CL, Spalluto CM, Legebeke J, Nazlamova L, Conforti F, Perotin J-M, Frank M et al. ( 2021 ) . A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection . Nature Genetics vol. 53 , ( 2 ) 205 - 214 .

Nguyen QPH, Liu Z, Albulescu A, Ouyang H, Zlock L, Coyaud E, Laurent E, Finkbeiner W et al. ( 2020 ) . Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia . Developmental Cell vol. 55 , ( 2 ) 209 - 223.e7 .

Liu Z, Nguyen QPH, Nanjundappa R, Delgehyr N, Megherbi A, Doherty R, Thompson J, Jackson C et al. ( 2020 ) . Super-Resolution Microscopy and FIB-SEM Imaging Reveal Parental Centriole-Derived, Hybrid Cilium in Mammalian Multiciliated Cells . Developmental Cell vol. 55 , ( 2 ) 224 - 236.e6 .

Liu Z, Costain G, Goczi A, Albulescu A, Walker S, Ngan B, Hall DA, Marshall CR et al. ( 2020 ) . Hereditary Mucin Deficiency Caused by Biallelic Loss-of-Function of MUC5B Defines a Novel Category of Lung Disease . Conference: C49. PEDIATRIC CYSTIC FIBROSIS, PCD, AND COUGHa5353 - a5353 .

Gopalakrishnan J, Mennella V, Blachon S, Zhai B, Smith AH, Megraw TL, Nicastro D, Gygi SP et al. ( 2020 ) . Author Correction: Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome . Nature Communications vol. 11 , ( 1 )

Liu Z, Nguyen QPH, Guan Q, Albulescu A, Erdman L, Mahdaviyeh Y, Kang J, Ouyang H et al. ( 2020 ) . A quantitative super-resolution imaging toolbox for diagnosis of motile ciliopathies . Science Translational Medicine vol. 12 , ( 535 )

Chioccioli M, Feriani L, Nguyen Q, Kotar J, Dell SD, Mennella V, Amirav I, Cicuta P ( 2019 ) . Quantitative High-Speed Video Profiling Discriminates between DNAH11 and HYDIN Variants of Primary Ciliary Dyskinesia . American Journal of Respiratory and Critical Care Medicine vol. 199 , ( 11 ) 1436 - 1438 .

Chioccioli M, Feriani L, Nguyen Q, Kotar J, Dell SDM, Mennella V, Amirav I, Cicuta P ( 2019 ) . Quantitative High Speed Video Profiling Discriminates Between Variants of Primary Ciliary Dyskinesia . Conference: D18. BEST OF NOVEL TECHNOLOGIES AND METHODOLOGIESa5883 - a5883 .

Sydor AM, Coyaud E, Rovelli C, Laurent E, Liu H, Raught B, Mennella V ( 2018 ) . PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN . eLife vol. 7 ,

Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller AL et al. ( 2018 ) . Author Correction: A novel atypical sperm centriole is functional during human fertilization . Nature Communications vol. 9 , ( 1 )

Wong KS, Mabanglo MF, Seraphim TV, Mollica A, Mao Y-Q, Rizzolo K, Leung E, Moutaoufik MT et al. ( 2018 ) . Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death . Cell Chemical Biology vol. 25 , ( 8 ) 1017 - 1030.e9 .

Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller AL et al. ( 2018 ) . A novel atypical sperm centriole is functional during human fertilization . Nature Communications vol. 9 , ( 1 )

Dell S, Liu Z, Nguyen Q, Mennella V ( 2017 ) . PCD Diagnosis by Super resolution (3DSIM) microscopy . Conference: Paediatric Bronchology

Khire A, Jo KH, Kong D, Akhshi T, Blachon S, Cekic AR, Hynek S, Ha A et al. ( 2016 ) . Centriole Remodeling during Spermiogenesis in Drosophila . Current Biology vol. 26 , ( 23 ) 3183 - 3189 .

Zheng Y, Mennella V, Marks S, Wildonger J, Elnagdi E, Agard DA, Megraw TL ( 2016 ) . The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in Drosophila . Molecular Biology of the Cell vol. 27 , ( 11 ) 1740 - 1752 .

Mennella V ( 2016 ) . Structured Illumination Microscopy . Encyclopedia of Cell Biology , Elsevier

Sydor AM, Czymmek KJ, Puchner EM, Mennella V ( 2015 ) . Super-Resolution Microscopy: From Single Molecules to Supramolecular Assemblies . Trends in Cell Biology vol. 25 , ( 12 ) 730 - 748 .

Mennella V, Hanna R, Kim M ( 2015 ) . Chapter 8 Subdiffraction resolution microscopy methods for analyzing centrosomes organization . Methods in Cell Biology vol. 129 , 129 - 152 .

Mennella V, Agard DA, Huang B, Pelletier L ( 2013 ) . Amorphous no more: subdiffraction view of the pericentriolar material architecture . Trends in Cell Biology vol. 24 , ( 3 ) 188 - 197 .

Miao Y, Wong CCL, Mennella V, Michelot A, Agard DA, Holt LJ, Yates JR, Drubin DG ( 2013 ) . Cell-cycle regulation of formin-mediated actin cable assembly . Proceedings of the National Academy of Sciences of the United States of America vol. 110 , ( 47 ) e4446 - e4455 .

Arigovindan M, Fung JC, Elnatan D, Mennella V, Chan Y-HM, Pollard M, Branlund E, Sedat JW et al. ( 2013 ) . High-resolution restoration of 3D structures from widefield images with extreme low signal-to-noise-ratio . Proceedings of the National Academy of Sciences of the United States of America vol. 110 , ( 43 ) 17344 - 17349 .

Mennella V, Keszthelyi B, McDonald KL, Chhun B, Kan F, Rogers GC, Huang B, Agard DA ( 2012 ) . Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization . Nature Cell Biology vol. 14 , ( 11 ) 1159 - 1168 .

Gopalakrishnan J, Mennella V, Blachon S, Zhai B, Smith AH, Megraw TL, Nicastro D, Gygi SP et al. ( 2011 ) . Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome . Nature Communications vol. 2 , ( 1 )

Mennella V, Tan D-Y, Buster DW, Asenjo AB, Rath U, Ma A, Sosa HJ, Sharp DJ ( 2009 ) . Motor domain phosphorylation and regulation of the Drosophila kinesin 13, KLP10A . Journal of Cell Biology vol. 186 , ( 4 ) 481 - 490 .

Tan D, Asenjo AB, Mennella V, Sharp DJ, Sosa H ( 2006 ) . Kinesin-13s form rings around microtubules . Journal of Cell Biology vol. 175 , ( 1 ) 25 - 31 .

Sharp DJ, Mennella V, Buster DW ( 2005 ) . KLP10A and KLP59C: The Dynamic Duo of Microtubule Depolymerization . Cell Cycle vol. 4 , ( 11 ) 1482 - 1485 .

Flego M, Mennella V, Moretti F, Poloni F, Dupuis ML, Ascione A, Barca S, Felici F et al. ( 2005 ) . Identification by Phage Display of the Linear Continuous MRPr1 Epitope in the Multidrug Resistance-Associated Protein (MRP1) . Biological Chemistry vol. 384 , ( 1 ) 139 - 142 .

Mennella V, Rogers GC, Rogers SL, Buster DW, Vale RD, Sharp DJ ( 2005 ) . Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase . Nature Cell Biology vol. 7 , ( 3 ) 235 - 245 .

Flego M, Ascione A, Pini A, Mennella V, Dupuis ML, Benagiano G, Cianfriglia M ( 2002 ) . Use of phage libraries for the in vitro production of recombinant monoclonal antibodies of predetermined specificity . Annali dell Istituto Superiore di Sanità vol. 38 , ( 4 ) 401 - 410 .

Fizzano MR, Valvo L, Dupuis ML, Mennella V, Cianfriglia M ( 2000 ) . LC determination of Indinavir in biological matrices with electrochemical detection . Journal of Pharmaceutical and Biomedical Analysis vol. 22 , ( 2 ) 307 - 314 .

Vijayakumaran A, Godbehere C, Abuammar A, Breusegem SY, Hurst LR, Morone N, Llodra J, Dalbay MT et al. . 3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication .

Chioccioli M, Feriani L, Nguyen Q, Kotar J, Dell SD, Mennella V, Amirav I, Cicuta P . A How-To guide to: Quantitative high-speed video profiling to discriminate between variants of primary ciliary dyskinesia .

Blume C, Jackson CL, Spalluto CM, Legebeke J, Nazlamova L, Conforti F, Perotin-Collard J-M, Frank M et al. . A novel isoform of ACE2 is expressed in human nasal and bronchial respiratory epithelia and is upregulated in response to RNA respiratory virus infection .

Wu Y, Tavares E, Liang B, Wee W, Mennella V, Feng H, Cao J, Zheng J et al. . RPGR regulates motile cilia by interfering with actin dynamics .

Nguyen QPH, Liu Z, Nanjundappa R, Megherbi A, Delgehyr N, Ouyang H, Zlock L, Coyaud E et al. . Super-resolution Molecular Map of Basal Foot Reveals Novel Cilium in Airway Multiciliated Cells .

. Volume EM reveals three-dimensional architecture of the desmosome in epithelial cells and tissue models .