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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Hui Zhao

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Pope B, Park G, Lau E, Belic J, Lach R, George A, McCoy P, Nguyen A et al. ( 2024 ) . Ultrasensitive Detection of Circulating Tumour DNA enriches for Patients with a Greater Risk of Recurrence of Clinically Localised Prostate Cancer . European Urology vol. 85 , ( 4 ) 407 - 410 .
Santonja A, Cooper WN, Eldridge MD, Edwards PAW, Morris JA, Edwards AR, Zhao H, Heider K et al. ( 2023 ) . Comparison of tumor‐informed and tumor‐naïve sequencing assays for ctDNA detection in breast cancer . EMBO Molecular Medicine vol. 15 , ( 6 )
Mouliere F, Smith CG, Heider K, Su J, van der Pol Y, Thompson M, Morris J, Wan JCM et al. ( 2021 ) . Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients . EMBO Molecular Medicine vol. 13 , ( 8 )
D’Anna F, Van Dyck L, Xiong J, Zhao H, Berrens RV, Qian J, Bieniasz-Krzywiec P, Chandra V et al. ( 2020 ) . DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance . Genome Biology vol. 21 , ( 1 )
Wong BW, Wang X, Zecchin A, Thienpont B, Cornelissen I, Kalucka J, García-Caballero M, Missiaen R et al. ( 2016 ) . The role of fatty acid β-oxidation in lymphangiogenesis . Nature vol. 542 , ( 7639 ) 49 - 54 .
Thienpont B, Steinbacher J, Zhao H, D’Anna F, Kuchnio A, Ploumakis A, Ghesquière B, Van Dyck L et al. ( 2016 ) . Tumour hypoxia causes DNA hypermethylation by reducing TET activity . Nature vol. 537 , ( 7618 ) 63 - 68 .
Cheng THT, Thompson DJ, O'Mara TA, Painter JN, Glubb DM, Flach S, Lewis A, French JD et al. ( 2016 ) . Five endometrial cancer risk loci identified through genome-wide association analysis . Nature Genetics vol. 48 , ( 6 ) 667 - 674 .
Lange C, Turrero Garcia M, Decimo I, Bifari F, Eelen G, Quaegebeur A, Boon R, Zhao H et al. ( 2016 ) . Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis . The EMBO Journal vol. 35 , ( 9 ) 924 - 941 .
Lambrechts S, Smeets D, Moisse M, Braicu EI, Vanderstichele A, Zhao H, Van Nieuwenhuysen E, Berns E et al. ( 2015 ) . Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer . European Journal of Cancer vol. 53 , 51 - 64 .
Wauters E, Janssens W, Vansteenkiste J, Decaluwé H, Heulens N, Thienpont B, Zhao H, Smeets D et al. ( 2015 ) . DNA methylation profiling of non-small cell lung cancer reveals a COPD-driven immune-related signature . Thorax vol. 70 , ( 12 )
Glubb DM, Maranian MJ, Michailidou K, Pooley KA, Meyer KB, Kar S, Carlebur S, O’Reilly M et al. ( 2014 ) . Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1 . American Journal of Human Genetics vol. 96 , ( 1 ) 5 - 20 .
Zhao H, Thienpont B, Yesilyurt BT, Moisse M, Reumers J, Coenegrachts L, Sagaert X, Schrauwen S et al. ( 2014 ) . Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks . eLife vol. 3 ,
Zhao H, Race V, Matthijs G, De Jonghe P, Robberecht W, Lambrechts D, Van Damme P ( 2013 ) . Exome sequencing reveals HINT1 mutations as a cause of distal hereditary motor neuropathy . European Journal of Human Genetics vol. 22 , ( 6 ) 847 - 850 .
Hein R, Maranian M, Hopper JL, Kapuscinski MK, Southey MC, Park DJ, Schmidt MK, Broeks A et al. ( 2012 ) . Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC) . PLOS ONE vol. 7 , ( 8 )
Herdewyn S, Zhao H, Moisse M, Race V, Matthijs G, Reumers J, Kusters B, Schelhaas HJ et al. ( 2012 ) . Whole-genome sequencing reveals a coding non-pathogenic variant tagging a non-coding pathogenic hexanucleotide repeat expansion in C9orf72 as cause of amyotrophic lateral sclerosis . Human Molecular Genetics vol. 21 , ( 11 ) 2412 - 2419 .
Reumers J, De Rijk P, Zhao H, Liekens A, Smeets D, Cleary J, Van Loo P, Van Den Bossche M et al. ( 2011 ) . Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing . Nature Biotechnology vol. 30 , ( 1 ) 61 - 68 .
Zhao H, Cloots L, Van den Bulcke T, Wu Y, De Smet R, Storms V, Meysman P, Engelen K et al. ( 2011 ) . Query-based biclustering of gene expression data using Probabilistic Relational Models . BMC Bioinformatics vol. 12 , ( Suppl 1 )
Thijs IM, Zhao H, De Weerdt A, Engelen K, De Coster D, Schoofs G, McClelland M, Vanderleyden J et al. ( 2010 ) . The AI-2-dependent regulator LsrR has a limited regulon in Salmonella Typhimurium . Cell Research vol. 20 , ( 8 ) 966 - 969 .
Janssens JCA, Steenackers H, Robijns S, Gellens E, Levin J, Zhao H, Hermans K, De Coster D et al. ( 2008 ) . Brominated Furanones Inhibit Biofilm Formation by Salmonella enterica Serovar Typhimurium . Applied and Environmental Microbiology vol. 74 , ( 21 ) 6639 - 6648 .
Zhao H, Engelen K, De Moor B, Marchal K ( 2007 ) . CALIB: a Bioconductor package for estimating absolute expression levels from two-color microarray data . Bioinformatics vol. 23 , ( 13 ) 1700 - 1701 .
Thijs IMV, De Keersmaecker SCJ, Fadda A, Engelen K, Zhao H, McClelland M, Marchal K, Vanderleyden J ( 2007 ) . Delineation of the Salmonella enterica Serovar Typhimurium HilA Regulon through Genome-Wide Location and Transcript Analysis . Journal of Bacteriology vol. 189 , ( 13 ) 4587 - 4596 .
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