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Research

Publications: DR Chloe Pasin

Waldecker M, Taghavi K, Pasin C, Tarr PE, Hachfeld A, Munting A, Abela IA, Weisser M et al. ( 2025 ) . Factors associated with uptake of gynaecological care and cervical cancer screening among women in the Swiss HIV Cohort Study . HIV Medicine vol. 26 , ( 12 ) 1963 - 1972 .
Pasin C, Weil B, Hayes R, Siddiqui Q, Whelan I, Nutland W, Maatouk I, Orkin CM et al. ( 2025 ) . ‘It was something that I let slip by the wayside’: a qualitative study of challenges to equitable mpox vaccination in the UK outbreak response . BMC Public Health vol. 25 , ( 1 )
Elias A, Pasin C, Smuk M, Paterson A, Orkin CM ( 2025 ) . Outcomes of real‐world initiation of long‐acting injectable cabotegravir and rilpivirine (LA‐I CAB + RPV) in individuals with viraemia: A systematic review of baseline characteristics, virological failure outcomes and discontinuations . HIV Medicine vol. 27 , ( 1 ) 42 - 57 .
Labarile M, Schoepf IC, Pasin C, Oumelloul MA, Thorball CW, Riebensahm C, Surial B, Wandeler G et al. ( 2025 ) . Untargeted Metabolite Profile Associations With Body Mass Index, Waist–Hip Ratio, and Antiretroviral Therapy in >1300 People With HIV: The Swiss HIV Cohort Study . Journal of Infectious Diseases
Zeeb M, Kusejko K, Hartnack S, Pasin C, Abela IA, Rusert P, Liechti T, Kadelka C et al. ( 2025 ) . Infection with Mycobacterium tuberculosis alters the antibody response to HIV-1 . PLOS Pathogens vol. 21 , ( 8 )
Pasin C, Orkin C ( 2025 ) . Editorial comment on: Gender equality in leadership of HIV care cascade clinical trials: A methodological study . HIV Medicine vol. 26 , ( 9 ) 1326 - 1328 .
Labarile M, Thorball CW, Hodel F, Fellay J, Tepekule B, Calmy A, Stöckle M, Damonti L et al. ( 2025 ) . Polygenic Risk Scores for Type 2 Diabetes in the Swiss HIV Cohort Study . JAIDS Journal of Acquired Immune Deficiency Syndromes vol. 100 , ( 1 ) 18 - 25 .
Hesselman MC, Zeeb M, Rusert P, Pasin C, Mamrosh J, Kariuki S, Pichler I, Sickmann M et al. ( 2025 ) . Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development . Cell Host & Microbe vol. 33 , ( 2 ) 279 - 293.e6 .
Foulkes C, Friedrich N, Ivan B, Stiegeler E, Magnus C, Schmidt D, Karakus U, Weber J et al. ( 2025 ) . Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity . PLOS Pathogens vol. 21 , ( 1 )
Jackson‐Perry D, Cart‐Richter E, Haerry D, Ahmeti L, Bieri A, Calmy A, Ballif M, Pasin C et al. ( 2024 ) . Patient and public involvement in HIV research: a mapping review and development of an online evidence map . Journal of the International AIDS Society vol. 27 , ( 11 )
Abela IA, Chammartin F, Amstutz A, Surial B, Ballif M, Marzolini C, Aebi-Popp K, Notter J et al. ( 2024 ) . Gender Disparities in Statin Prescriptions in People With HIV With Low/Moderate to High Cardiovascular Risk . Open Forum Infectious Diseases vol. 11 , ( 9 )
Neuner-Jehle N, Zeeb M, Thorball CW, Fellay J, Metzner KJ, Frischknecht P, Neumann K, Leeman C et al. ( 2024 ) . Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen . PLOS Pathogens vol. 20 , ( 8 )
Pasin C, Nuñez DG, Kusejko K, Hachfeld A, Buvelot H, Cavassini M, Damonti L, Fux C et al. ( 2024 ) . Impact of hormonal therapy on HIV‐1 immune markers in cis women and gender minorities . HIV Medicine vol. 25 , ( 10 ) 1112 - 1124 .
Zeeb M, Pasin C, Cavassini M, Bieler-Aeschlimann M, Frischknecht P, Kusejko K, Fellay J, Blanquart F et al. ( 2024 ) . Self-reported neurocognitive complaints in the Swiss HIV Cohort Study: a viral genome-wide association study . Brain Communications vol. 6 , ( 4 )
Turk T, Labarile M, Braun DL, Rauch A, Stöckle M, Cavassini M, Hoffmann M, Calmy A et al. ( 2024 ) . Characterization and Determinants of Long-Term Immune Recovery Under Suppressive Antiretroviral Therapy . JAIDS Journal of Acquired Immune Deficiency Syndromes vol. 96 , ( 1 ) 68 - 76 .
Trepl J, Pasin C, Schneidawind D, Mueller NJ, Manz MG, Bankova AK, Abela IA ( 2024 ) . Evaluating tixagevimab/cilgavimab prophylaxis in allogeneic haematopoietic cell transplantation recipients for COVID‐19 prevention . British Journal of Haematology vol. 204 , ( 5 ) 1908 - 1912 .
Abela IA, Schwarzmüller M, Ulyte A, Radtke T, Haile SR, Ammann P, Raineri A, Rueegg S et al. ( 2024 ) . Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection . mBio vol. 15 , ( 2 ) e02722 - e02723 .
Abela IA, Hauser A, Schwarzmüller M, Pasin C, Kusejko K, Epp S, Cavassini M, Battegay M et al. ( 2024 ) . Deciphering Factors Linked With Reduced Severe Acute Respiratory Syndrome Coronavirus 2 Susceptibility in the Swiss HIV Cohort Study . Journal of Infectious Diseases vol. 230 , ( 2 ) e292 - e304 .
Maliqi L, Friedrich N, Glögl M, Schmutz S, Schmidt D, Rusert P, Schanz M, Zaheri M et al. ( 2023 ) . Assessing immunogenicity barriers of the HIV-1 envelope trimer . npj Vaccines vol. 8 , ( 1 )
Pasin C, Consiglio CR, Huisman JS, de Lange A-MG, Peckham H, Vallejo-Yagüe E, Abela IA, Islander U et al. ( 2023 ) . Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical applications . Royal Society Open Science vol. 10 , ( 7 )
Brown JA, Hauser A, Abela IA, Pasin C, Epp S, Mohloanyane T, Nsakala BL, Trkola A et al. ( 2023 ) . Seroprofiling of Antibodies Against Endemic Human Coronaviruses and Severe Acute Respiratory Syndrome Coronavirus 2 in a Human Immunodeficiency Virus Cohort in Lesotho: Correlates of Antibody Response and Seropositivity . Journal of Infectious Diseases vol. 228 , ( 8 ) 1042 - 1054 .
Labarile M, Loosli T, Zeeb M, Kusejko K, Huber M, Hirsch HH, Perreau M, Ramette A et al. ( 2022 ) . Quantifying and Predicting Ongoing Human Immunodeficiency Virus Type 1 Transmission Dynamics in Switzerland Using a Distance-Based Clustering Approach . Journal of Infectious Diseases vol. 227 , ( 4 ) 554 - 564 .
Bankova AK, Pasin C, Huang A, Cicin‐Sain C, Epp S, Audige A, Mueller NJ, Nilsson J et al. ( 2022 ) . Antibody response to a third SARS‐CoV‐2 vaccine dose in recipients of an allogeneic haematopoietic cell transplantation . British Journal of Haematology vol. 201 , ( 1 ) 58 - 63 .
Chammartin F, Kusejko K, Pasin C, Trkola A, Briel M, Amico P, Stoekle MP, Eichenberger AL et al. ( 2022 ) . Determinants of antibody response to severe acute respiratory syndrome coronavirus 2 mRNA vaccines in people with HIV . AIDS vol. 36 , ( 10 ) 1465 - 1468 .
Marconato M, Abela IA, Hauser A, Schwarzmüller M, Katzensteiner R, Braun DL, Epp S, Audigé A et al. ( 2022 ) . Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response . Journal of Clinical Investigation vol. 132 , ( 12 )
Huang A, Cicin-Sain C, Pasin C, Epp S, Audigé A, Müller NJ, Nilsson J, Bankova A et al. ( 2022 ) . Antibody Response to SARS-CoV-2 Vaccination in Patients following Allogeneic Hematopoietic Cell Transplantation . Transplantation and Cellular Therapy vol. 28 , ( 4 ) 214.e1 - 214.e11 .
Abela IA, Pasin C, Schwarzmüller M, Epp S, Sickmann ME, Schanz MM, Rusert P, Weber J et al. ( 2021 ) . Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity . Nature Communications vol. 12 , ( 1 )
Macedo R, Pasin C, Ganetsky A, Harle D, Wang XK, Belay K, Richman LP, Huffman AP et al. ( 2021 ) . Vitamin D deficiency after allogeneic hematopoietic cell transplantation promotes T-cell activation and is inversely associated with an EZH2-ID3 signature . Transplantation and Cellular Therapy vol. 28 , ( 1 ) 18.e1 - 18.e10 .
Szabo PA, Dogra P, Gray JI, Wells SB, Connors TJ, Weisberg SP, Krupska I, Matsumoto R et al. ( 2021 ) . Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19 . Immunity vol. 54 , ( 4 ) 797 - 814.e6 .
Pasin C, Moy RH, Reshef R, Yates AJ ( 2021 ) . Variable selection methods for predicting clinical outcomes following allogeneic hematopoietic cell transplantation . Scientific Reports vol. 11 , ( 1 )
Balelli I, Pasin C, Prague M, Crauste F, Effelterre TV, Bockstal V, Solforosi L, Thiébaut R ( 2020 ) . A model for establishment, maintenance and reactivation of the immune response after vaccination against Ebola virus . Journal of Theoretical Biology vol. 495 ,
Pasin C, Balelli I, Van Effelterre T, Bockstal V, Solforosi L, Prague M, Douoguih M, Thiébaut R ( 2019 ) . Dynamics of the Humoral Immune Response to a Prime-Boost Ebola Vaccine: Quantification and Sources of Variation . Journal of Virology vol. 93 , ( 18 ) 10.1128/jvi.00579 - 10.1128/jvi.00519 .
Pasin C, Halloran ME, Gilbert PB, Langevin E, Ochiai RL, Pitisuttithum P, Capeding MR, Carrasquilla G et al. ( 2018 ) . Periods of high dengue transmission defined by rainfall do not impact efficacy of dengue vaccine in regions of endemic disease . PLOS ONE vol. 13 , ( 12 )
Villain L, Commenges D, Pasin C, Prague M, Thiébaut R ( 2018 ) . Adaptive protocols based on predictions from a mechanistic model of the effect of IL7 on CD4 counts . Statistics in Medicine vol. 38 , ( 2 ) 221 - 235 .
Pasin C, Dufour F, Villain L, Zhang H, Thiébaut R ( 2018 ) . Controlling IL-7 Injections in HIV-Infected Patients . Bulletin of Mathematical Biology vol. 80 , ( 9 ) 2349 - 2377 .
Gross L, Lhomme E, Pasin C, Richert L, Thiebaut R ( 2018 ) . Ebola vaccine development: Systematic review of pre-clinical and clinical studies, and meta-analysis of determinants of antibody response variability after vaccination . International Journal of Infectious Diseases vol. 74 , 83 - 96 .
Lhomme E, Richert L, Moodie Z, Pasin C, Kalams SA, Morgan C, Self S, De Rosa SC et al. ( 2016 ) . Early CD4+ T Cell Responses Are Associated with Subsequent CD8+ T Cell Responses to an rAd5-Based Prophylactic Prime-Boost HIV Vaccine Strategy . PLOS ONE vol. 11 , ( 4 )
Jackson-Perry D, Cart-Richter E, Haerry D, Ahmeti L, Bieri A, Calmy A, Ballif M, Pasin C et al. . Patient and Public Involvement in HIV research: a mapping review and development of an online evidence map .
Pasin C, Rusert P, Schmidt D, Schanz M, Friedrich N, Abela IA, Kusejko K, Niklaus C et al. . The XbnAb Cohort: 304 people with broadly neutralizing antibody activity to HIV-1 .
Prague M, Gerold JM, Balelli I, Pasin C, Li JZ, Barouch DH, Whitney JB, Hill AL . Viral rebound kinetics following single and combination immunotherapy for HIV/SIV .