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  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: DR Mine Koprulu

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Pietzner M, Beuchel C, Demircan K, Hoffmann Anton J, Zeng W, Römisch-Margl W, Yasmeen S, Uluvar B et al. ( 2025 ) . Machine learning-guided deconvolution of plasma protein levels . Molecular Systems Biology1 - 23 .
Zoodsma M, Beuchel C, Yasmeen S, Kohleick L, Nepal A, Koprulu M, Kronenberg F, Mayr M et al. ( 2025 ) . A genetic map of human metabolism across the allele frequency spectrum . Nature Genetics vol. 57 , ( 10 ) 2445 - 2455 .
Koprulu M, Wheeler E, Kerrison ND, Denaxas S, Carrasco-Zanini J, Orkin CM, Hemingway H, Wareham NJ et al. ( 2025 ) . Sex differences in the genetic regulation of the human plasma proteome . Nature Communications vol. 16 , ( 1 )
Carrasco-Zanini J, Wheeler E, Uluvar B, Kerrison N, Koprulu M, Wareham NJ, Pietzner M, Langenberg C ( 2024 ) . Mapping biological influences on the human plasma proteome beyond the genome . Nature Metabolism vol. 6 , ( 10 ) 2010 - 2023 .
Carrasco-Zanini J, Pietzner M, Koprulu M, Wheeler E, Kerrison ND, Wareham NJ, Langenberg C ( 2024 ) . Proteomic prediction of diverse incident diseases: a machine learning-guided biomarker discovery study using data from a prospective cohort study . The Lancet Digital Health vol. 6 , ( 7 ) e470 - e479 .
Desai TA, Hedman ÅK, Dimitriou M, Koprulu M, Figiel S, Yin W, Johansson M, Watts EL et al. ( 2024 ) . Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics . EBioMedicine vol. 105 ,
Smith-Byrne K, Hedman Å, Dimitriou M, Desai T, Sokolov AV, Schioth HB, Koprulu M, Pietzner M et al. ( 2024 ) . Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers . Nature Communications vol. 15 , ( 1 )
Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, Naudin C, Munsch G, Goumidi L, Farm M, Smith PM et al. ( 2023 ) . Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism . Nature Communications vol. 14 , ( 1 )
Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, Naudin C, Munsch G, Goumidi L, Farm M, Smith PM et al. ( 2023 ) . Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism . Nature Communications vol. 14 , ( 1 )
Koprulu M, Carrasco-Zanini J, Wheeler E, Lockhart S, Kerrison ND, Wareham NJ, Pietzner M, Langenberg C ( 2023 ) . Author Correction: Proteogenomic links to human metabolic diseases . Nature Metabolism vol. 5 , ( 4 ) 710 - 710 .
Koprulu M, Carrasco-Zanini J, Wheeler E, Lockhart S, Kerrison ND, Wareham NJ, Pietzner M, Langenberg C ( 2023 ) . Proteogenomic links to human metabolic diseases . Nature Metabolism vol. 5 , ( 3 ) 516 - 528 .
Zanetti D, Koprulu M, Grosso F, Zhernakova DV, Crobu F, Sanna S . Exploring sex-specific causal links between thousands of proteins and lipid metabolism using the UK Biobank Pharma proteomics data .
Desai TA, Hedman ÅK, Dimitriou M, Koprulu M, Figiel S, Yin W, Johansson M, Watts EL et al. . Identifying proteomic risk factors for overall, aggressive and early onset prostate cancer using Mendelian randomization and tumor spatial transcriptomics .
Smith-Byrne K, Hedman Å, Dimitriou M, Desai T, Sokolov AV, Schioth HB, Koprulu M, Pietzner M et al. . Identifying therapeutic targets for cancer: 2,094 circulating proteins and risk of nine cancers .
Pietzner M, Beuchel C, Demircan K, Anton JH, Zeng W, Römisch-Margl W, Yasmeen S, Uluvar B et al. . Machine learning-guided deconvolution of plasma protein levels .
Pietzner M, Williamson A, Hunt KA, Koprulu M, Kohleick L, Demircan K, Team GHR, Finer S et al. . Nanoparticle enriched mass spectrometry proteomics in British South Asians identifies novel variant-protein-disease mechanisms .
Zanini JC, Pietzner M, Koprulu M, Zoodsma M, Williamson A, Hunt KA, Manolias A, Walter K et al. . Proteomic and clinical impact of human knockouts in British South Asians .
Koprulu M, Wheeler E, Kerrison ND, Denaxas S, Carrasco-Zanini J, Orkin CM, Hemingway H, Wareham NJ et al. . Similar and different: systematic investigation of proteogenomic variation between sexes and its relevance for human diseases .
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