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Research

Publications: Miss Raine Astin-Chamberlain

Boeddinghaus J, Bima P, Crisanti L, Keller DI, Slankamenac K, Christ M, Schuetz P, Wiencierz A et al. ( 2025 ) . PRospective evaluation of the European Society of Cardiology 0/1h-algorithm`s safety and efficacy for triage of patients with suspected myocardial infarction (PRESC1SE-MI): Rationale and design of a prospective international multicenter stepped-wedge cluster randomized controlled trial . American Heart Journal vol. 292 ,
Abani O, Abbas A, Abbas F, Abbas K, Abbas M, Abbasi J, Abbasi S, Abbass H et al. ( 2025 ) . Sotrovimab versus usual care in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet Infectious Diseases vol. 26 , ( 1 ) 34 - 45 .
Bloom B, Haimovich A, Pott J, Williams SL, Cheetham M, Langsted S, Skene I, Astin-Chamberlain R et al. ( 2025 ) . Digitalizing English-language CT Interpretation for Positive Haemorrhage Evaluation Reporting: the DECIPHER study . BMJ Health & Care Informatics vol. 32 , ( 1 )
Skene IP, Astin-Chamberlain R, Pike KC, Griffiths C, Steed L, Pfeffer PE ( 2025 ) . Optimising long-term management in acute asthma presentations to the emergency department: an interview study on patient beliefs . BMJ Open Respiratory Research vol. 12 , ( 1 )
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2025 ) . Molnupiravir or nirmatrelvir–ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet Infectious Diseases vol. 25 , ( 9 ) 1000 - 1010 .
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2025 ) . Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial . EClinicalMedicine vol. 81 ,
Astin-Chamberlain R, Pott J, Cole E, Bloom BM ( 2024 ) . Sex and gender reporting in UK emergency medicine trials from 2010 to 2023: a systematic review . Emergency Medicine Journal vol. 42 , ( 2 ) 82 - 90 .
Boos J, van der Made CI, Ramakrishnan G, Coughlan E, Asselta R, Löscher B-S, Valenti LVC, de Cid R et al. ( 2024 ) . Stratified analyses refine association between TLR7 rare variants and severe COVID-19 . Human Genetics and Genomics Advances vol. 5 , ( 4 )
Bloom B, Fritz CL, Gupta S, Pott J, Skene I, Astin-Chamberlain R, Ali M, Thomas SA et al. ( 2024 ) . Older age and risk for delayed abdominal pain care in the emergency department . European Journal of Emergency Medicine vol. 31 , ( 5 ) 332 - 338 .
Faust SN, Haynes R, Jones CE, Staplin N, Whittaker E, Jaki T, Juszczak E, Spata E et al. ( 2024 ) . Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet Child & Adolescent Health vol. 8 , ( 3 ) 190 - 200 .
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2023 ) . Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet Diabetes & Endocrinology vol. 11 , ( 12 ) 905 - 914 .
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2023 ) . Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 401 , ( 10387 ) 1499 - 1507 .
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2022 ) . Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis . The Lancet vol. 400 , ( 10349 ) 359 - 368 .
Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2022 ) . Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 399 , ( 10325 ) 665 - 676 .
Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2021 ) . Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 399 , ( 10320 ) 143 - 151 .
Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2021 ) . Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial . The Lancet vol. 397 , ( 10289 ) 2049 - 2059 .
Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2021 ) . Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 397 , ( 10285 ) 1637 - 1645 .
Abaleke E, Abbas M, Abbasi S, Abbott A, Abdelaziz A, Abdelbadiee S, Abdelfattah M, Abdul B et al. ( 2021 ) . Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 397 , ( 10274 ) 605 - 612 .
Millar J, Nichol A, Walsh T, Shankar-Hari M, Ponting C, Meikle J, Finernan P, Mcmaster E et al. ( 2020 ) . Genetic mechanisms of critical illness in COVID-19 . Nature vol. 591 , ( 7848 ) 92 - 98 .