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Research

Publications: MR Graeme Thorn

Thorn GJ, Gadaleta E, Dayem Ullah AZM, James LGE, Abdollahyan M, Barrow-McGee R, Jones LJ, Chelala C ( 2025 ) . The clinical and molecular landscape of breast cancer in women of African and South Asian ancestry . Nature Communications vol. 16 , ( 1 ) Article 4237 ,
Lawrence S, Lin J, Khurshid A, Utami W, Singhania R, Ashraf S, Thorn GJ, Mangangcha IR et al. ( 2024 ) . Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study . FEBS Letters vol. 599 , ( 3 ) 415 - 435 .
Oscanoa J, Ross-Adams H, Dayem Ullah AZM, Kolvekar TS, Sivapalan L, Gadaleta E, Thorn GJ, Abdollahyan M et al. ( 2024 ) . A central research portal for mining pancreatic clinical and molecular datasets and accessing biobanked samples .
Thorn GJ, Gadaleta E, Dayem Ullah AZM, James LGE, Abdollahyan M, Barrow-McGee R, Jones JL, Chelala C ( 2024 ) . The clinical and molecular landscape of breast cancer in women of African and South Asian ancestry .
Jacob DR, Guiblet WM, Mamayusupova H, Shtumpf M, Ciuta I, Ruje L, Gretton S, Bikova M et al. ( 2024 ) . Nucleosome reorganisation in breast cancer tissues . Clinical Epigenetics vol. 16 , ( 1 ) Article 50 ,
Latreille J, Thorn G, Jdid R, Gendronneau G, Tabara Y, Harada Y, Forestier S, Chelala C et al. ( 2023 ) . 541 Gene set enrichment analysis identifies biological networks associated with skin aging in a large Japanese population: Data from the Nagahama cohort . Journal of Investigative Dermatology vol. 143 , ( 5 ) S93 - S93 .
Oscanoa J, Latreille J, Le Clerc S, Muther C, Thorn G, Gendronneau G, Matsuda F, Forestier S et al. ( 2023 ) . 902 Development of a web-based platform to facilitate research to uncover the skin ageing mechanism . Journal of Investigative Dermatology vol. 143 , ( 5 ) S154 - S154 .
Jacob DR, Guiblet WM, Mamayusupova H, Shtumpf M, Ciuta I, Ruje L, Gretton S, Bikova M et al. ( 2023 ) . Nucleosome reorganisation in breast cancer tissues .
Oscanoa J, Latreille J, Le Clerc S, Muther C, Thorn G, Gendronneau G, Matsuda F, Forestier S et al. ( 2023 ) . Development of a web-based platform to facilitate research to uncover the skin ageing mechanism . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 143 , S154 - S154 .
Latreille J, Thorn G, Jdid R, Gendronneau G, Tabara Y, Harada Y, Forestier S, Chelala C et al. ( 2023 ) . Gene set enrichment analysis identifies biological networks associated with skin aging in a large Japanese population: Data from the Nagahama cohort . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 143 , S93 - S93 .
Gadaleta E, Thorn GJ, Ross‐Adams H, Jones LJ, Chelala C ( 2022 ) . Field cancerization in breast cancer . The Journal of Pathology vol. 257 , ( 4 ) 561 - 574 .
Sivapalan L, Thorn GJ, Gadaleta E, Kocher HM, Ross-Adams H, Chelala C ( 2022 ) . Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer . BMC Cancer vol. 22 , ( 1 ) Article 369 ,
Thorn GJ, Clarkson CT, Rademacher A, Mamayusupova H, Schotta G, Rippe K, Teif VB ( 2022 ) . DNA sequence-dependent formation of heterochromatin nanodomains . Nature Communications vol. 13 , ( 1 ) Article 1861 ,
Sivapalan L, Thorn G, Gadaleta E, Kocher H, Ross-Adams H, Chelala C ( 2021 ) . Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer .
Thorn GJ, Clarkson CT, Rademacher A, Mamayusupova H, Schotta G, Rippe K, Teif VB ( 2020 ) . DNA sequence-dependent formation of heterochromatin nanodomains .
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al. ( 2020 ) . Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer . npj Breast Cancer vol. 6 , ( 1 ) Article 38 ,
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al. ( 2020 ) . Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer . NPJ breast cancer vol. 6 , ( 1 )
Pirrò S, Spada F, Gadaleta E, Ferrentino F, Thorn GJ, Cesareni G, Chelala C ( 2020 ) . HiPPO and PANDA: Two Bioinformatics Tools to Support Analysis of Mass Cytometry Data . Journal of Computational Biology vol. 27 , ( 8 ) 1283 - 1294 .
Singhania R, Thorn GJ, Williams K, Gandhi RD, Daher C, Barthet-Barateig A, Parker HN, Utami W et al. ( 2019 ) . Nuclear poly(A) tail size is regulated by Cnot1 during the serum response .
Wiehle L, Thorn GJ, Raddatz G, Clarkson CT, Rippe K, Lyko F, Breiling A, Teif VB ( 2019 ) . DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries . Genome Research vol. 29 , ( 5 ) 750 - 761 .
Ashraf S, Radhi M, Gowler P, Burston JJ, Gandhi RD, Thorn GJ, Piccinini AM, Walsh DA et al. ( 2019 ) . The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis . Scientific Reports vol. 9 , ( 1 ) Article 4696 ,
Thorn GJ, King JR ( 2016 ) . Modelling the role of CtfA/B in reverse shift continuous culture experiments of Clostridium acetobutylicum . Mathematical Biosciences vol. 276 , 101 - 113 .
Thorn GJ, King JR ( 2016 ) . The metabolic network of Clostridium acetobutylicum: Comparison of the approximate Bayesian computation via sequential Monte Carlo (ABC-SMC) and profile likelihood estimation (PLE) methods for determinability analysis . Mathematical Biosciences vol. 271 , 62 - 79 .
Millat T, Janssen H, Thorn GJ, King JR, Bahl H, Fischer R-J, Wolkenhauer O ( 2013 ) . A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicumin phosphate-limited continuous cultures . Applied Microbiology and Biotechnology vol. 97 , ( 14 ) 6451 - 6466 .
Thorn GJ, King JR, Jabbari S ( 2013 ) . pH-induced gene regulation of solvent production by Clostridium acetobutylicum in continuous culture: Parameter estimation and sporulation modelling . Mathematical Biosciences vol. 241 , ( 2 ) 149 - 166 .
BEARON RN, HAZEL AL, THORN GJ ( 2011 ) . The spatial distribution of gyrotactic swimming micro-organisms in laminar flow fields . Journal of Fluid Mechanics vol. 680 , 602 - 635 .
Boakes DE, Codling EA, Thorn GJ, Steinke M ( 2010 ) . Analysis and modelling of swimming behaviour in Oxyrrhis marina . Journal of Plankton Research vol. 33 , ( 4 ) 641 - 649 .
Codling EA, Bearon RN, Thorn GJ ( 2010 ) . Diffusion about the mean drift location in a biased random walk . Ecology vol. 91 , ( 10 ) 3106 - 3113 .
Thorn GJ, Bearon RN ( 2010 ) . Transport of spherical gyrotactic organisms in general three-dimensional flow fields . Physics of Fluids vol. 22 , ( 4 ) Article 041902 ,