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Research

Publications: Dr Amelia Acha-Sagredo

Ganguli P, Basanta CC, Acha-Sagredo A, Misetic H, Armero M, Mendez A, Zahra A, Devonshire G et al. ( 2025 ) . Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer . Nature Cancer vol. 6 , ( 1 ) 158 - 174 .
Acha-Sagredo A, Ganguli P, Ciccarelli FD ( 2022 ) . Somatic variation in normal tissues: friend or foe of cancer early detection? . Annals of Oncology vol. 33 , ( 12 ) 1239 - 1249 .
Bortolomeazzi M, Montorsi L, Temelkovski D, Keddar MR, Acha-Sagredo A, Pitcher MJ, Basso G, Laghi L et al. ( 2022 ) . A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution . Nature Communications vol. 13 , ( 1 )
Dressler L, Bortolomeazzi M, Keddar MR, Misetic H, Sartini G, Acha-Sagredo A, Montorsi L, Wijewardhane N et al. ( 2022 ) . Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource . Genome Biology vol. 23 , ( 1 )
Acha-Sagredo A, Malanchi I, Ciccarelli FD ( 2021 ) . Clone competition as a mechanism to reduce tumor formation . Developmental Cell vol. 56 , ( 24 ) 3307 - 3308 .
Bortolomeazzi M, Keddar MR, Montorsi L, Acha-Sagredo A, Benedetti L, Temelkovski D, Choi S, Petrov N et al. ( 2021 ) . Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts . Gastroenterology vol. 161 , ( 4 ) 1179 - 1193 .