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Research

Publications: Dr Gabor Czibik

Perna L, Salsbury G, Dushti M, Smith CJ, Morales V, Bianchi K, Czibik G, Chapple JP ( 2024 ) . Altered Cellular Metabolism Is a Consequence of Loss of the Ataxia-Linked Protein Sacsin . International Journal of Molecular Sciences vol. 25 , ( 24 )
Naushad S, Gaucher J, Mezdari Z, Détrait M, Belaidi E, Zhang Y, Vial G, Bouyon S et al. ( 2024 ) . Chronic intermittent hypoxia triggers cardiac fibrosis: Role of epididymal white adipose tissue senescent remodeling? . Acta Physiologica vol. 240 , ( 11 )
Derumeaux G, Sawaki D, Czibik G ( 2024 ) . Trajectories in Cardiac Aging: Journey to the Crossroads of Inflammation and Metabolism . Circulation vol. 149 , ( 25 ) 1935 - 1937 .
Sanpawithayakul K, Czibik G, Korbonits M ( 2023 ) . Live Fast, Die Young? . The Journal of Clinical Endocrinology & Metabolism vol. 109 , ( 1 ) e426 - e427 .
Sawaki D, Zhang Y, Mohamadi A, Pini M, Mezdari Z, Lipskaia L, Naushad S, Lamendour L et al. ( 2023 ) . Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction . JCI Insight vol. 8 , ( 8 )
Lezoualc’h F, Badimon L, Baker H, Bernard M, Czibik G, de Boer RA, D’Humières T, Kergoat M et al. ( 2022 ) . Diabetic cardiomyopathy: the need for adjusting experimental models to meet clinical reality . Cardiovascular Research vol. 119 , ( 5 ) 1130 - 1145 .
Czibik G, d’Humières T, Derumeaux G ( 2021 ) . When does too much energy become a danger to the heart? . European Heart Journal vol. 43 , ( 9 ) 878 - 880 .
Pini M, Czibik G, Sawaki D, Mezdari Z, Braud L, Delmont T, Mercedes R, Martel C et al. ( 2021 ) . Adipose tissue senescence is mediated by increased ATP content after a short‐term high‐fat diet exposure . Aging Cell vol. 20 , ( 8 )
Czibik G, Mezdari Z, Altintas DM, Bréhat J, Pini M, d’Humières T, Delmont T, Radu C et al. ( 2021 ) . Dysregulated Phenylalanine Catabolism Plays a Key Role in the Trajectory of Cardiac Aging . Circulation vol. 144 , ( 7 ) 559 - 574 .
Mougenot N, Mika D, Czibik G, Marcos E, Abid S, Houssaini A, Vallin B, Guellich A et al. ( 2019 ) . Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction . Cardiovascular Research vol. 115 , ( 12 ) 1778 - 1790 .
Sawaki D, Czibik G, Pini M, Ternacle J, Suffee N, Mercedes R, Marcelin G, Surenaud M et al. ( 2018 ) . Visceral Adipose Tissue Drives Cardiac Aging Through Modulation of Fibroblast Senescence by Osteopontin Production . Circulation vol. 138 , ( 8 ) 809 - 822 .
Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV et al. ( 2017 ) . Mammalian γ2 AMPK regulates intrinsic heart rate . Nat Commun vol. 8 , ( 1 ) 1258 - 1258 .
Ernande L, Audureau E, Jellis CL, Bergerot C, Henegar C, Sawaki D, Czibik G, Volpi C et al. ( 2017 ) . Clinical Implications of Echocardiographic Phenotypes of Patients With Diabetes Mellitus . Journal of the American College of Cardiology vol. 70 , ( 14 ) 1704 - 1716 .
Ternacle J, Wan F, Sawaki D, Surenaud M, Pini M, Mercedes R, Ernande L, Audureau E et al. ( 2017 ) . Short-term high-fat diet compromises myocardial function: a radial strain rate imaging study . European Heart Journal - Cardiovascular Imaging vol. 18 , ( 11 ) 1283 - 1291 .
Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M et al. ( 2016 ) . Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function . Cell Metabolism vol. 23 , ( 5 ) 821 - 836 .
Ashrafian H, Czibik G, Bellahcene M, Aksentijević D, Smith AC, Mitchell SJ, Dodd MS, Kirwan J et al. ( 2012 ) . Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway . Cell Metabolism vol. 15 , ( 3 ) 361 - 371 .
Czibik G, Sagave J, Martinov V, Ishaq B, Sohl M, Sefland I, Carlsen H, Farnebo F et al. ( 2009 ) . Cardioprotection by hypoxia-inducible factor 1 alpha transfection in skeletal muscle is dependent on haem oxygenase activity in mice . Cardiovascular Research vol. 82 , ( 1 ) 107 - 114 .