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Research

Publications: MISS Rachel Suk Munn Lau

( 2025 ) . Spatial mapping of rheumatoid arthritis synovial niches reveals a LYVE1+ macrophage network associated with response to therapy . Annals of the Rheumatic Diseases
Lewis MJ, Çubuk C, Surace AEA, Sciacca E, Lau R, Goldmann K, Giorli G, Fossati-Jimack L et al. ( 2025 ) . Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis . Nature Communications vol. 16 , ( 1 ) Article 5374 ,
Banda N, Moreland LW, Deane KD, Simberg D, Scheinman RI, Frank RM, Clay MR, Seifert JA et al. ( 2025 ) . Analysis of human factor H-related gene and protein expression in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation . Immunobiology vol. 230 , ( 4 ) Article 153016 , 153016 - 153016 .
Banda NK, Moreland LW, Deane KD, Simberg D, Scheinman RI, Frank RM, Seifert JA, Anolik J et al. ( 2025 ) . Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation . Scientific Reports vol. 15 , ( 1 ) Article 19633 ,
Martínez-Paz P, Nerviani A, Cubuk C, Lau R, Fossati-Jimack L, Rivellese F, Somma D, Alivernini S et al. ( 2025 ) . POS0070 SPECIFIC SYNOVIAL TISSUE MACROPHAGE CLUSTER SUBTYPES ARE ASSOCIATED WITH MULTI-BIOLOGIC REFRACTORINESS IN RHEUMATOID ARTHRITIS . Annals of the Rheumatic Diseases vol. 84 , 376 - 376 .
Bhamidipati K, McIntyre ABR, Kazerounian S, Ce G, Tran M, Prell SA, Lau R, Khedgikar V et al. ( 2025 ) . Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis .
Kontra I, Ward H, Vinluan F, Lau R, Rajeeve V, Cutillas P, Stieglitz B, Lewis MJ ( 2025 ) . The acidic N-terminus of HHARI and neddylation are essential for the activation and maintenance of RIG-I-mediated type I interferon response .
Çubuk C, Lau R, Cutillas P, Rajeeve V, John CR, Surace AEA, Hands R, Fossati-Jimack L et al. ( 2024 ) . Phosphoproteomic profiling of early rheumatoid arthritis synovium reveals active signalling pathways and differentiates inflammatory pathotypes . Arthritis Research & Therapy vol. 26 , ( 1 ) Article 120 ,
Lau R, Cubuk C, Rajeeve V, Cutillas P, Hands R, Fossati-Jimack L, Surace A, Lewis M et al. ( 2024 ) . OP0218 SYNOVIAL PHOSPHOPROTEOME ANALYSIS OF LATE-STAGE RHEUMATOID ARTHRITIS PATIENTS (R4RA TRIAL) IDENTIFIES SIGNALLING PATHWAYS ASSOCIATED WITH PATHOTYPE AND RESPONSE TO RITUXIMAB AND TOCILIZUMAB . Annals of the Rheumatic Diseases . vol. 83 , 12 - 12 .
Wang S, Nair N, Cubuk C, Yap CF, Lau R, Giorli G, Fossati-Jimack L, Plant D et al. ( 2024 ) . OP0224 INTEGRATION OF DNA METHYLATION INTO MULTI-OMIC ANALYSIS OF SYNOVIAL BIOPSIES FROM THE STRAP RANDOMIZED CLINICAL TRIAL IDENTIFIES PREDICTORS OF RESPONSE TO ANTI-TNF THERAPY IN RHEUMATOID ARTHRITIS . Annals of the Rheumatic Diseases . vol. 83 , 13 - 13 .
Nerviani A, Boutet M-A, Ghirardi GM, Goldmann K, Sciacca E, Rivellese F, Pontarini E, Prediletto E et al. ( 2024 ) . Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis . Nature Communications vol. 15 , ( 1 ) Article 2398 ,
Lau R, Yu L, Roumeliotis TI, Stewart A, Pickard L, Riisanes R, Gurel B, de Bono JS et al. ( 2023 ) . Unbiased differential proteomic profiling between cancer-associated fibroblasts and cancer cell lines . Journal of Proteomics vol. 288 , Article 104973 , 104973 - 104973 .