Publications: P Jianhua Wu

( 2025 ) . Protocol for the OPTIMSE-1 randomised clinical trial to test specialist-led identification and management of cardio-renal-metabolic-pulmonary disease in machine learning algorithm-detected high-risk community-dwelling individuals . BMJ Open vol. 15 , ( 8 ) e101088 - e101088 .

Helbitz A, Haris M, Younsi T, Romer E, Ginks W, Raveendra K, Hayward C, Shuweihdi F et al. ( 2025 ) . Prediction of atrial fibrillation after a stroke event: A systematic review with meta-analysis . Heart Rhythm vol. 22 , ( 7 ) 1637 - 1645 .

Helbitz A, Nadarajah R, Mu L, Larvin H, Ismail H, Wahab A, Thompson P, Harrison P et al. ( 2025 ) . Identification, characterisation and outcomes of pre‐atrial fibrillation in heart failure with reduced ejection fraction . ESC Heart Failure Article ehf2.15347 ,

Bhatty A, Wilkinson C, Aktaa S, Batra G, Beska B, Khaing PH, Wahab A, Raveendra K et al. ( 2025 ) . Outcome measures for randomised clinical trials and multicentre observational studies of cardiovascular diseases published in major clinical journals: systematic review and evidence mapping . Heart

Kang J, Luo H, Wu J ( 2025 ) . Editorial: The association between oral health and mental health . Frontiers in Oral Health vol. 6 , Article 1610146 ,

Wahab A, Nadarajah R, Larvin H, Farooq M, Raveendra K, Haris M, Nadeem U, Joseph T et al. ( 2025 ) . Systematic screening for atrial fibrillation with non-invasive devices: a systematic review and meta-analysis . The Lancet Regional Health - Europe vol. 53 , Article 101298 , 101298 - 101298 .

Hayward C, Ismail H, M Nakao Y, Wu J, Nadarajah R, P Gale C ( 2025 ) . Prediction of atrial fibrillation in patients without heart failure: validation study in 3.3 million individuals . Europace vol. 27 , ( Supplement_1 ) Article euaf085.857 ,

Helbitz A, Nadarajah R, Wu J, Larvin H, Mu L, Younsi T, Swoboda P, Gale CP ( 2025 ) . The 'pre-AF substrate' in patients with heart failure . Europace vol. 27 , ( Supplement_1 ) Article euaf085.017 ,

Wahab A, Tomoia R, Nadarajah R, Javed W, Bennett S, Bhatty AB, Larvin H, Wu J et al. ( 2025 ) . Myocardial tissue characterisation in high-risk pre-atrial fibrillation patients . European Journal of Preventive Cardiology vol. 32 , ( Supplement_1 ) Article zwaf236.009 ,

Gao C, Iles MM, Bishop DT, Larvin H, Bunce D, Wu B, Luo H, Nibali L et al. ( 2025 ) . Correction to: Genetic risk factors for periodontitis: a genome-wide association study using UK Biobank data . Clinical Oral Investigations vol. 29 , ( 4 ) Article 198 ,

Brown JRG, Baptiste PJ, Hajmohammadi H, Nadarajah R, Gale CP, Wu J ( 2025 ) . Impact of neighbourhood and environmental factors on the risk of incident cardiovascular disease: a systematic review and meta-analysis . European Journal of Preventive Cardiology Article zwaf165 ,

Gao C, Iles MM, Bishop DT, Larvin H, Bunce D, Wu B, Luo H, Nibali L et al. ( 2025 ) . Genetic risk factors for periodontitis: a genome-wide association study using UK Biobank data . Clinical Oral Investigations vol. 29 , ( 2 ) Article 129 ,

Hamilton E, Shone L, Reynolds C, Wu J, Nadarajah R, Gale C ( 2025 ) . Perceptions of healthcare professionals on the use of a risk prediction model to inform atrial fibrillation screening: qualitative interview study in English primary care . BMJ Open vol. 15 , ( 2 ) e091675 - e091675 .

( 2025 ) . Improving the timeliness and equity of preschool childhood vaccinations: Mixed methods evaluation of a quality improvement programme in primary care . Vaccine vol. 43 , Article 126522 , 126522 - 126522 .

Kang J, Larvin H, Pavitt S, Wu J ( 2024 ) . Higher Prevalence of Tooth Loss in People With Abdominal Obesity but Normal Weight: Findings From the United States and Scottish Populations . Clinical and Experimental Dental Research vol. 10 , ( 6 ) Article e70047 ,

Tyl B, Costa A, Vora P, Farjat A, Sandrak P, Nadarajah R, Wanner C, Wilson D et al. ( 2024 ) . Association of a history of acute kidney injury with major adverse cardiovascular events in chronic kidney disease patients . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.3259 ,

Nadarajah R, Nakao YM, Shuweihdi F, Hsu JC, Wahab A, Helbitz A, Nakao K, Hayward C et al. ( 2024 ) . Machine learning for prediction of incident heart failure and heart failure hospitalisation: multi-cohort development, validation and association with clinical phenotypes . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.3475 ,

Nadarajah R, Wahab A, Reynolds C, Mohammad H, Bhatty A, Hurdus B, Nadeem U, Bennet S et al. ( 2024 ) . Machine learning identifies individuals at higher risk of incident cardio-renal-metabolic diseases and cardiovascular death who have unrealised opportunities to reduce future cardiovascular risk . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.2689 ,

Nadarajah R, Wu J, Nakao YM, Hsu JC, Helbitz A, Nakao K, Lin LY, Gale CP ( 2024 ) . Machine learning to predict incident atrial fibrillation in patients with acute stroke: FIND-AF STROKE . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.3520 ,

Wahab A, Nadarajah R, Reynolds C, Bennett S, Ambakederemo E, Harris M, Younsi T, Joseph T et al. ( 2024 ) . Phenotypic characterization of people at risk of atrial fibrillation: protocol for the FIND-AF longitudinal cohort study . European Journal of Preventive Cardiology vol. 31 , ( 18 ) 2099 - 2103 .

Gao C, Iles M, Larvin H, Bishop DT, Bunce D, Ide M, Sun F, Pavitt S et al. ( 2024 ) . Genome-wide association studies on periodontitis: A systematic review . PLOS ONE vol. 19 , ( 9 ) e0306983 - e0306983 .

Kang J, Wu J, Aggarwal VR, Shiers D, Doran T, Palmier-Claus J ( 2024 ) . Investigating the Relationship between Oral Health and Severe Mental Illness: Analysis of NHANES 1999–2016 . Dentistry Journal vol. 12 , ( 7 ) 191 - 191 .

Nadarajah R, Wahab A, Reynolds C, Hogg DC, Raveendra K, Bennett S, Nakao YM, Nakao K et al. ( 2024 ) . Development, validation and prospective clinical implementation of a machine learning algorithm for incident cardio-renal-metabolic diseases and cardiovascular death: the OPTIMISE study . European Journal of Preventive Cardiology vol. 31 , ( Supplement_1 ) Article zwae175.312 ,

Wu J, Nadarajah R, Nakao YM, Nakao K, Arbel R, Haim M, Zahger D, Lip GYH et al. ( 2024 ) . Risk calculator for incident atrial fibrillation across a range of prediction horizons . American Heart Journal vol. 272 , 1 - 10 .

Alzubaidi MA, Drummond BK, Wu J, Jones A, Aggarwal VR ( 2024 ) . Interventions to Reduce Intra-Operative and Post-Operative Pain Associated with Routine Dental Procedures in Children: A Systematic Review and Meta-Analysis . Dentistry Journal vol. 12 , ( 6 ) 163 - 163 .

Nadarajah R, Nakao Y, Shuweihdi F, Hsu J-C, Wahab A, Helbitz A, Nakao K, Hayward C et al. ( 2024 ) . 145 Machine learning for prediction of incident heart failure and heart failure hospitalisation: developlment, validation and assocation with clinical phenotypes . Heart failure . Conference: British Cardiovascular Society Annual Conference, ‘Back to the patient’, 3–5 June 2024A155.1 - A155 .

Nadarajah R, Wahab A, Reynolds C, Bhatty A, Mohammad H, Raveendra K, Younsi T, Romer E et al. ( 2024 ) . 204 Machine learning for incident cardio-renal-metabolic disease and cardiovascular death: the optimise study . Stable IHD/Prevention/Hypertension/Lipids . Conference: British Cardiovascular Society Annual Conference, ‘Back to the patient’, 3–5 June 2024A215 - A216 .

Larvin H, Baptiste PJ, Gao C, Muirhead V, Donos N, Pavitt S, Kang J, Wu J ( 2024 ) . All‐cause and cause‐specific mortality in <scp>US</scp> adults with periodontal diseases: A prospective cohort study . Journal of Clinical Periodontology vol. 51 , ( 9 ) 1157 - 1167 .

Younsi T, Romer E, Haris M, Nguyen L, Acheson L, Jassam Walker M, Larvin H, Wu J et al. ( 2024 ) . Burden of atrial fibrillation risk and outcomes amongst patients attending cardiology and elderly medicine services: prospective in-hospital implementation of the FIND-AF algorithm . Europace vol. 26 , ( Supplement_1 ) Article euae102.568 ,

Helbitz A, Haris M, Younsi T, Romer E, Raveendra K, Hayward C, Shuweihdi F, Larvin H et al. ( 2024 ) . Prediction of atrial fibrillation in patients with stroke: a systematic review with meta-analysis . Europace vol. 26 , ( Supplement_1 ) Article euae102.042 ,

Raveendra K, Larvin H, Farooq M, Mohammed H, Wu J, Gale C, Nadarajah R ( 2024 ) . Primary prevention of atrial fibrillation with pharmacological therapy . Europace vol. 26 , ( Supplement_1 ) Article euae102.829 ,

Zhou Y, Lyratzopoulos G, Rajan P, Walter FM, Wu J ( 2024 ) . Understanding symptom contribution to sex inequality in bladder and renal cancer stage at diagnosis . BJUI Compass vol. 5 , ( 7 ) 805 - 812 .

Haris M, Raveendra K, Travlos CK, Lewington A, Wu J, Shuweidhi F, Nadarajah R, Gale CP ( 2024 ) . Prediction of incident chronic kidney disease in community-based electronic health records: a systematic review and meta-analysis . Clinical Kidney Journal vol. 17 , ( 5 ) Article sfae098 ,

Wu J, Nadarajah R ( 2024 ) . The growing burden of atrial fibrillation and its consequences . BMJq826 - q826 .

Walshaw EG, Rogers S, Wu J, Sandars J, Kanatas A ( 2024 ) . The Evaluation of Training Oral and Maxillofacial Trainees in Head and Neck Cancer Doctor-Patient Communication Using the Patient Concerns Inventory . Acta Medica (Hradec Kralove, Czech Republic) vol. 66 , ( 4 ) 146 - 153 .

Nadarajah R, Wahab A, Reynolds C, Bhatty A, Mohammad H, Raveendra K, Bennett S, Younsi T et al. ( 2024 ) . Machine learning to identify community-dwelling individuals at higher risk of incident cardio-renal-metabolic diseases and death . Future Healthcare Journal vol. 11 , Article 100109 , 100109 - 100109 .

Hall M, Smith L, Wu J, Hayward C, Batty JA, Lambert PC, Hemingway H, Gale CP ( 2024 ) . Health outcomes after myocardial infarction: A population study of 56 million people in England . PLOS Medicine vol. 21 , ( 2 ) e1004343 - e1004343 .

Nakao YM, Nadarajah R, Shuweihdi F, Nakao K, Fuat A, Moore J, Bates C, Wu J et al. ( 2024 ) . Predicting incident heart failure from population-based nationwide electronic health records: protocol for a model development and validation study . BMJ Open vol. 14 , ( 1 ) e073455 - e073455 .

Alzubaidi MA, Drummond BK, Wu J, Jones A, Tahmassebi JF, Aggarwal VR ( 2023 ) . Predictors of Intra-Operative and Post-Operative Pain Associated with Routine Dental Procedures in Children: A Systematic Review and Meta-Analysis . Dentistry Journal vol. 12 , ( 1 ) 4 - 4 .

Nadarajah R, Wu J, Arbel R, Haim M, Zahger D, Benita TR, Rokach L, Cowan JC et al. ( 2023 ) . Risk of atrial fibrillation and association with other diseases: protocol of the derivation and international external validation of a prediction model using nationwide population-based electronic health records . BMJ Open vol. 13 , ( 12 ) e075196 - e075196 .

Nadarajah R, Mohammad H, Younsi T, Romer E, Raveendra K, Travlos C, Wahab A, Nakao YMN et al. ( 2023 ) . A systematic review and meta-analysis of prediction models for incident heart failure and chronic kidney disease in community-based electronic health records . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.2951 ,

Wilkinson C, Austin D, Wu J, Gale CP, Quinn T, Burgoine T ( 2023 ) . Association between distance to nearest automated external defibrillator and socioeconomic deprivation in Great Britain . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.3020 ,

Hayward C, Batty J, Westhead DR, Johnson O, Gale CP, Wu J, Hall M ( 2023 ) . Disease trajectories following myocardial infarction: insights from process mining of 145 million hospitalisation episodes . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.2940 ,

Hall M, Smith L, Wu J, Hayward C, Batty JA, Lambert PC, Hemingway H, Gale CP ( 2023 ) . Health outcomes after myocardial infarction: a population study of 56 million people in England . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.1212 ,

Nadarajah R, Wu J, Nakao YM, Nakao K, Wilkinson C, Cowan JC, Camm AJ, Gale CP ( 2023 ) . Temporal trends and patterns in cause-specific mortality and hospitalisations after incident atrial fibrillation in England from 2001 to 2017 . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.277 ,

Gao C, Larvin H, Bishop DT, Bunce D, Pavitt S, Wu J, Kang J ( 2023 ) . Oral diseases are associated with cognitive function in adults over 60 years old . Oral Diseases vol. 30 , ( 5 ) 3480 - 3488 .

Hayward CJ, Batty JA, Westhead DR, Johnson O, Gale CP, Wu J, Hall M ( 2023 ) . Disease trajectories following myocardial infarction: insights from process mining of 145 million hospitalisation episodes . eBioMedicine vol. 96 , Article 104792 , 104792 - 104792 .

Nadarajah R, Farooq M, Raveendra K, Nakao YM, Nakao K, Wilkinson C, Wu J, Gale CP ( 2023 ) . Inequalities in care delivery and outcomes for myocardial infarction, heart failure, atrial fibrillation, and aortic stenosis in the United Kingdom . The Lancet Regional Health - Europe vol. 33 , Article 100719 , 100719 - 100719 .

Nadarajah R, Wahab A, Reynolds C, Raveendra K, Askham D, Dawson R, Keene J, Shanghavi S et al. ( 2023 ) . Future Innovations in Novel Detection for Atrial Fibrillation (FIND-AF): pilot study of an electronic health record machine learning algorithm-guided intervention to identify undiagnosed atrial fibrillation . Open Heart vol. 10 , ( 2 ) e002447 - e002447 .

Nakao YM, Nakao K, Nadarajah R, Banerjee A, Fonarow GC, Petrie MC, Rahimi K, Wu J et al. ( 2023 ) . Prognosis, characteristics, and provision of care for patients with the unspecified heart failure electronic health record phenotype: a population-based linked cohort study of 95262 individuals . eClinicalMedicine vol. 63 , Article 102164 , 102164 - 102164 .

Burgoine T, Austin D, Wu J, Quinn T, Shurmer P, Gale CP, Wilkinson C ( 2023 ) . Automated external defibrillator location and socioeconomic deprivation in Great Britain . Heart vol. 110 , ( 3 ) 188 - 194 .

Wu J, Nadarajah R, Nakao YM, Nakao K, Wilkinson C, Cowan JC, Camm AJ, Gale CP ( 2023 ) . Temporal trends of cause-specific mortality after diagnosis of atrial fibrillation . European Heart Journal vol. 44 , ( 42 ) 4422 - 4431 .

Nadarajah R, Nakao YM, Wu J, Gale CP ( 2023 ) . Using routinely collected health record data for the earlier detection of heart failure with preserved ejection fraction: FIND-HFpEF . European Heart Journal vol. 44 , ( 33 ) 3113 - 3115 .

Duquenne L, Hensor EM, Wilson M, Garcia-Montoya L, Nam JL, Wu J, Harnden K, Anioke IC et al. ( 2023 ) . Predicting Inflammatory Arthritis in At-Risk Persons: Development of Scores for Risk Stratification . Annals of Internal Medicine vol. 176 , ( 8 ) 1027 - 1036 .

Nadarajah R, Younsi T, Romer E, Raveendra K, Nakao YM, Nakao K, Shuweidhi F, Hogg DC et al. ( 2023 ) . Prediction models for heart failure in the community: A systematic review and meta‐analysis . European Journal of Heart Failure vol. 25 , ( 10 ) 1724 - 1738 .

Wu J, Nadarajah R, Nakao YM, Nakao K, Hogg D, Raveendra K, Arbel R, Haim M et al. ( 2023 ) . Incident cardiovascular, renal, metabolic diseases and death in individuals identified for risk-guided atrial fibrillation screening: a nationwide cohort study . Open Heart vol. 10 , ( 2 ) e002357 - e002357 .

Nadarajah R, Wu J, Hogg D, Raveendra K, Nakao Y, Nakao K, Arbel R, Haim M et al. ( 2023 ) . Development, validation and outcomes associated with a risk prediction algorithm for incident atrial fibrillation: retrospective national cohort study of 2 081 139 individuals . Europace vol. 25 , ( Supplement_1 ) Article euad122.543 ,

Kanatas A, Walshaw EG, Wu J, Fabbroni G, Chengot P ( 2023 ) . Prognostic factors in oral cancer surgery - results from a UK tertiary centre . European Journal of Surgical Oncology vol. 49 , ( 4 ) 755 - 759 .

( 2023 ) . The impact of study factors in the association of periodontal disease and cognitive disorders: systematic review and meta-analysis . Age and Ageing vol. 52 , ( 2 ) Article afad015 ,

Nadarajah R, Wu J, Hogg D, Raveendra K, Nakao YM, Nakao K, Arbel R, Haim M et al. ( 2023 ) . Prediction of short-term atrial fibrillation risk using primary care electronic health records . Heart vol. 109 , ( 14 ) 1072 - 1079 .

Nakao K, Dafaalla M, Nakao YM, Wu J, Nadarajah R, Rashid M, Mohammad H, Sumita Y et al. ( 2023 ) . Comparison of care and outcomes for myocardial infarction by heart failure status between United Kingdom and Japan . ESC Heart Failure vol. 10 , ( 2 ) 1372 - 1384 .

Nakao YM, Nakao K, Wu J, Nadarajah R, Camm AJ, Gale CP ( 2022 ) . Risks and benefits of oral anticoagulants for stroke prophylaxis in atrial fibrillation according to body mass index: Nationwide cohort study of primary care records in England . eClinicalMedicine vol. 54 , Article 101709 , 101709 - 101709 .

( 2022 ) . Periodontitis and risk of immune‐mediated systemic conditions: A systematic review and meta‐analysis . Community Dentistry and Oral Epidemiology vol. 51 , ( 5 ) 705 - 717 .

Kang J, Palmier‐Claus J, Wu J, Shiers D, Larvin H, Doran T, Aggarwal VR ( 2022 ) . Periodontal disease in people with a history of psychosis: Results from the <scp>UK</scp> biobank population‐based study . Community Dentistry and Oral Epidemiology vol. 51 , ( 5 ) 985 - 996 .

( 2022 ) . Data standards for transcatheter aortic valve implantation: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart) . European Heart Journal - Quality of Care and Clinical Outcomes vol. 9 , ( 5 ) 529 - 536 .

Wu J, Nadarajah R, Nakao Y, Nakao K, Wilkinson C, Raveendra K, Mamas MA, Camm AJ et al. ( 2022 ) . Temporal trends and patterns in atrial fibrillation incidence: a population-based study of 3.4 million individuals . European Heart Journal vol. 43 , ( Supplement_2 ) Article ehac544.528 ,

( 2022 ) . Rates of Elective Percutaneous Coronary Intervention in England and Wales: Impact of COURAGE and ORBITA Trials . Journal of the American Heart Association vol. 11 , ( 18 ) Article e025426 ,

Jowett AC, Littlewood SJ, Hodge TM, Dhaliwal HK, Wu J ( 2022 ) . CAD/CAM nitinol bonded retainer versus a chairside rectangular-chain bonded retainer: A multicentre randomised controlled trial . Journal of Orthodontics vol. 50 , ( 1 ) 55 - 68 .

Singhota S, Tchantchaleishvili N, Wu J, Zrinzo L, Thorne L, Akram H, Zakrzewska JM ( 2022 ) . Long term evaluation of a multidisciplinary trigeminal neuralgia service . The Journal of Headache and Pain vol. 23 , ( 1 ) Article 114 ,

Wu J, He W ( 2022 ) . Editorial: Nutrition and infections . Frontiers in Nutrition vol. 9 , Article 992095 ,

( 2022 ) . Diagnostic accuracy of splinter haemorrhages in patients referred for suspected infective endocarditis . Heart vol. 108 , ( 24 ) 1986 - 1990 .

Singhota S, Tchantchaleishvili N, Wu J, Zrinzo L, Thorne L, Akram H, Zakrzewska J ( 2022 ) . Long term evaluation of a multidisciplinary trigeminal neuralgia service .

( 2022 ) . Systemic Multimorbidity Clusters in People with Periodontitis . Journal of Dental Research vol. 101 , ( 11 ) 1335 - 1342 .

Wu J, Nadarajah R, Nakao YM, Nakao K, Wilkinson C, Mamas MA, Camm AJ, Gale CP ( 2022 ) . Temporal trends and patterns in atrial fibrillation incidence: A population-based study of 3·4 million individuals . The Lancet Regional Health - Europe vol. 17 , Article 100386 , 100386 - 100386 .

Nadarajah R, Wu J, Hurdus B, Asma S, Bhatt DL, Biondi-Zoccai G, Mehta LS, Ram CVS et al. ( 2022 ) . The collateral damage of COVID-19 to cardiovascular services: a meta-analysis . European Heart Journal vol. 43 , ( 33 ) 3164 - 3178 .

( 2022 ) . The additive effect of periodontitis with hypertension on risk of systemic disease and mortality . Journal of Periodontology vol. 93 , ( 7 ) 1024 - 1035 .

Wu J, Nadarajah R, Raveendra K, Cowan JC, Gale CP ( 2022 ) . FIND-AF: a widely applicable artificial intelligence algorithm to target systematic screening for atrial fibrillation in older individuals through primary care electronic health records . EP Europace vol. 24 , ( Supplement_1 ) Article euac053.565 ,

( 2022 ) . Impact of oral anticoagulation on the association between frailty and clinical outcomes in people with atrial fibrillation: nationwide primary care records on treatment analysis . EP Europace vol. 24 , ( 7 ) 1065 - 1075 .

Hadanny A, Shouval R, Wu J, Gale CP, Unger R, Zahger D, Gottlieb S, Matetzky S et al. ( 2022 ) . Machine learning-based prediction of 1-year mortality for acute coronary syndrome✰ . Journal of Cardiology vol. 79 , ( 3 ) 342 - 351 .

Gul HL, Di Matteo A, Mankia K, Wu J, Ponchel F, Emery P ( 2022 ) . Can biomarkers predict successful tapering of conventional disease-modifying therapy in rheumatoid arthritis patients in stable remission? . Clinical and Experimental Rheumatology

( 2021 ) . What is next for screening for undiagnosed atrial fibrillation? Artificial intelligence may hold the key . European Heart Journal - Quality of Care and Clinical Outcomes vol. 8 , ( 4 ) 391 - 397 .

Nadarajah R, Wu J, Frangi AF, Hogg D, Cowan C, Gale C ( 2021 ) . Predicting patient-level new-onset atrial fibrillation from population-based nationwide electronic health records: protocol of FIND-AF for developing a precision medicine prediction model using artificial intelligence . BMJ Open vol. 11 , ( 11 ) e052887 - e052887 .

Hadanny A, Shouval R, Wu J, Shlomo N, Unger R, Zahger D, Matetzky S, Goldenberg I et al. ( 2021 ) . Predicting 30-day mortality after ST elevation myocardial infarction: Machine learning- based random forest and its external validation using two independent nationwide datasets . Journal of Cardiology vol. 78 , ( 5 ) 439 - 446 .

( 2021 ) . Association of quality indicators for acute myocardial infarction and mortality: feasibility and validation study using linked nationwide registry data . European Heart Journal vol. 42 , ( Supplement_1 ) Article ehab724.1328 ,

( 2021 ) . Prediction of incident atrial fibrillation in community-based electronic health records: a systematic review with meta-analysis . Heart vol. 108 , ( 13 ) 1020 - 1029 .

( 2021 ) . Multimorbid disease trajectories for people with periodontitis . Journal of Clinical Periodontology vol. 48 , ( 12 ) 1587 - 1596 .

Aggarwal VR, Wu J, Fox F, Howdon D, Guthrie E, Mighell A ( 2021 ) . Implementation of biopsychosocial supported self‐management for chronic primary oro‐facial pain including temporomandibular disorders: A theory, person and evidence‐based approach . Journal of Oral Rehabilitation vol. 48 , ( 10 ) 1118 - 1128 .

Larvin H, Wilmott S, Kang J, Aggarwal VR, Pavitt S, Wu J ( 2021 ) . Additive Effect of Periodontal Disease and Obesity on COVID-19 Outcomes . Journal of Dental Research vol. 100 , ( 11 ) 1228 - 1235 .

( 2021 ) . Quality of acute myocardial infarction care in England and Wales during the COVID-19 pandemic: linked nationwide cohort study . BMJ Quality &amp; Safety vol. 31 , ( 2 ) 116 - 122 .

Patel K, Godazandeh K, Wu J, Zakrzewska JM ( 2021 ) . The Journeys of Patients with Trigeminal Neuralgia on a Background of Multiple Sclerosis . Pain Management vol. 11 , ( 5 ) 561 - 569 .

( 2021 ) . Incidence and mortality due to thromboembolic events during the COVID-19 pandemic: Multi-sourced population-based health records cohort study . Thrombosis Research vol. 202 , 17 - 23 .

( 2021 ) . Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic . European Heart Journal - Quality of Care and Clinical Outcomes vol. 7 , ( 4 ) 378 - 387 .

( 2021 ) . Receptor activator of nuclear factor kappa-Β ligand (RANKL) serum levels are associated with progression to seropositive/negative rheumatoid arthritis . Clinical and Experimental Rheumatology vol. 39 , ( 3 ) 456 - 462 .

( 2021 ) . Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Aortic Stenosis in England . Circulation: Cardiovascular Interventions vol. 14 , ( 5 ) Article e010413 ,

Kite TA, Ludman PF, Gale CP, Wu J, Caixeta A, Mansourati J, Sabate M, Jimenez-Quevedo P et al. ( 2021 ) . International Prospective Registry of Acute Coronary Syndromes in Patients With COVID-19 . Journal of the American College of Cardiology vol. 77 , ( 20 ) 2466 - 2476 .

Kang J, Wu J ( 2021 ) . The trends in maternal age distribution and the estimated live birth and population prevalence of Down’s syndrome in China: 1985-2012 .

( 2021 ) . Place and Underlying Cause of Death During the COVID-19 Pandemic: Retrospective Cohort Study of 3.5 Million Deaths in England and Wales, 2014 to 2020 . Mayo Clinic Proceedings vol. 96 , ( 4 ) 952 - 963 .

Kang J, Wu J, Aggarwal V, Shiers D, Doran T, Palmier-Claus J ( 2021 ) . Oral health inequality in people with severe mental illness: a cross-sectional study using National Health and Nutrition Examination Survey 1999-2016 .

( 2021 ) . Outcomes of COVID‐19‐positive acute coronary syndrome patients: A multisource electronic healthcare records study from England . Journal of Internal Medicine vol. 290 , ( 1 ) 88 - 100 .

( 2021 ) . Racial differences in management and outcomes of acute myocardial infarction during COVID-19 pandemic . Heart vol. 107 , ( 9 ) 734 - 740 .

Wu J, Mamas MA, de Belder MA, Deanfield JE, Gale CP ( 2021 ) . Second Decline in Admissions With Heart Failure and Myocardial Infarction During the COVID-19 Pandemic . Journal of the American College of Cardiology vol. 77 , ( 8 ) 1141 - 1143 .

( 2021 ) . Long-term survival benefit of ramipril in patients with acute myocardial infarction complicated by heart failure . Heart vol. 107 , ( 5 ) 389 - 395 .

Singhota S, Tchantchaleishvili N, Wu J, Zrinzo L, Thorne L, Zakrzewska JM ( 2021 ) . A joint medical and surgical multidisciplinary trigeminal neuralgia service eleven-year evaluation . JOURNAL OF HEADACHE AND PAIN . vol. 22 ,

Osnes C, Wu J, Ferrari M, Joda T, Keeling A ( 2021 ) . Sources of error in maximum intercuspation from complete dentate full-arch intraoral scans in vitro . INTERNATIONAL JOURNAL OF COMPUTERIZED DENTISTRY vol. 24 , ( 3 ) 283 - 291 .

Alajmi S, Muhanna H, Alfozan M, Asadallah M, Alkhamees Z, Wu J, Khalid S, Osnes C et al. ( 2021 ) . Surface area coverage of four extra-oral 3D scanning strategies for edentulous arches . JOURNAL OF OSSEOINTEGRATION vol. 13 , ( 4 ) S279 - S284 .

Wilkinson C, Wu J, Searle SD, Todd O, Hall M, Kunadian V, Clegg A, Rockwood K et al. ( 2020 ) . Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial . BMC Medicine vol. 18 , ( 1 ) Article 401 ,

( 2020 ) . In-Hospital and 30-Day Mortality After Percutaneous Coronary Intervention in England in the Pre-COVID and COVID Eras . Journal of Invasive Cardiology vol. 33 , ( 3 )

Pujades-Rodriguez M, Morgan AW, Cubbon RM, Wu J ( 2020 ) . Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study . PLOS Medicine vol. 17 , ( 12 ) e1003432 - e1003432 .

Larvin H, Wilmott S, Wu J, Kang J ( 2020 ) . The Impact of Periodontal Disease on Hospital Admission and Mortality During COVID-19 Pandemic . Frontiers in Medicine vol. 7 , Article 604980 ,

( 2020 ) . Impact of Coronavirus Disease 2019 Pandemic on the Incidence and Management of Out‐of‐Hospital Cardiac Arrest in Patients Presenting With Acute Myocardial Infarction in England . Journal of the American Heart Association vol. 9 , ( 22 ) Article e018379 ,

Larvin H, Kang J, Aggarwal VR, Pavitt S, Wu J ( 2020 ) . Risk of incident cardiovascular disease in people with periodontal disease: A systematic review and meta‐analysis . Clinical and Experimental Dental Research vol. 7 , ( 1 ) 109 - 122 .

Orlowski A, Gale CP, Ashton R, Petrungaro B, Slater R, Nadarajah R, Cowan JC, Buck J et al. ( 2020 ) . Clinical and budget impacts of changes in oral anticoagulation prescribing for atrial fibrillation . Heart vol. 107 , ( 1 ) 47 - 53 .

( 2020 ) . Sex Differences in Mortality Rates and Underlying Conditions for COVID-19 Deaths in England and Wales . Mayo Clinic Proceedings vol. 95 , ( 10 ) 2110 - 2124 .

Wu J, Mamas MA, Mohamed MO, Kwok CS, Roebuck C, Humberstone B, Denwood T, Luescher T et al. ( 2020 ) . Place and causes of acute cardiovascular mortality during the COVID-19 pandemic . Heart vol. 107 , ( 2 ) 113 - 119 .

( 2020 ) . Impact of COVID-19 on percutaneous coronary intervention for ST-elevation myocardial infarction . Heart vol. 106 , ( 23 ) 1805 - 1811 .

( 2020 ) . Clinical Characteristics and Outcomes of COVID-19 Positive Acute Coronary Syndrome Patients; a multisource Electronic Healthcare Records Study from England .

Wu J, Malfam M, Mamas M, Rashid M, Kontopantelis E, Deanfield JE, de Belder MA, Gale CP ( 2020 ) . Place and underlying cause of death during the COVID19 pandemic: retrospective cohort study of 3.5 million deaths in England and Wales, 2014 to 2020 .

Martin GP, Curzen N, Goodwin AT, Nolan J, Balacumaraswami L, Ludman P, Kontopantelis E, Wu J et al. ( 2020 ) . Indirect Impact of the COVID-19 Pandemic on Activity and Outcomes of Transcatheter and Surgical Treatment of Severe Aortic Stenosis in England .

Wu J, Alsaeed ES, Barrett J, Hall M, Cowan C, Gale CP ( 2020 ) . Prescription of oral anticoagulants and antiplatelets for stroke prophylaxis in atrial fibrillation: nationwide time series ecological analysis . EP Europace vol. 22 , ( 9 ) 1311 - 1319 .

( 2020 ) . Patient response, treatments, and mortality for acute myocardial infarction during the COVID-19 pandemic . European Heart Journal - Quality of Care and Clinical Outcomes vol. 7 , ( 3 ) 238 - 246 .

Wu J, Mackie SL, Pujades-Rodriguez M ( 2020 ) . Glucocorticoid dose-dependent risk of type 2 diabetes in six immune-mediated inflammatory diseases: a population-based cohort analysis . BMJ Open Diabetes Research &amp; Care vol. 8 , ( 1 ) e001220 - e001220 .

Mohamed MO, Kinnaird T, Curzen N, Ludman P, Wu J, Rashid M, Shoaib A, de Belder M et al. ( 2020 ) . In-hospital and 30-day mortality after percutaneous coronary intervention in England before and after the COVID-19 era .

Coats RO, Crossley KL, Conlin N, Wu J, Zakrzewska JM, Pavitt SH, Phillips N, Mon-Williams M ( 2020 ) . Cognitive and sensorimotor function in participants being treated for trigeminal neuralgia pain . The Journal of Headache and Pain vol. 21 , ( 1 ) Article 91 ,

Wu J, Mamas MA, Mohamed M, Kwok CS, Roebuck C, Humberstone B, Denwood T, Luescher T et al. ( 2020 ) . Place and causes of acute cardiovascular mortality during the COVID19 pandemic: retrospective cohort study of 580,972 deaths in England and Wales, 2014 to 2020 .

Osnes C, Duke A, Wu J, Franklin P, Mushtaq F, Keeling A ( 2020 ) . Investigating the construct validity of a haptic virtual caries simulation for\n dental education . BMJ Simulation and Technology Enhanced Learning vol. 7 , ( 2 ) 81 - 85 .

Ali N, Baig W, Wu J, Blackman D, Gillott R, Sandoe JAT ( 2020 ) . Prosthetic valve endocarditis following transcatheter aortic valve implantation . Journal of Cardiovascular Medicine vol. 21 , ( 7 ) 510 - 516 .

Pujades-Rodriguez M, Morgan AW, Cubbon RM, Wu J ( 2020 ) . Dose-dependent oral glucocorticoid cardiovascular risk in people with immune-mediated inflammatory diseases .

( 2020 ) . Bidirectional relations between cognitive function and oral health in ageing persons: a longitudinal cohort study . Age and Ageing vol. 49 , ( 5 ) 793 - 799 .

Osnes CA, Wu JH, Venezia P, Ferrari M, Keeling AJ ( 2020 ) . Full arch precision of six intraoral scanners in vitro . Journal of Prosthodontic Research vol. 64 , ( 1 ) 6 - 11 .

( 2019 ) . Assessing the perceived impact of post Minamata amalgam phase down on oral health inequalities: a mixed-methods investigation . BMC Health Services Research vol. 19 , ( 1 ) Article 985 ,

Fawcett N, Young B, Peto L, Quan TP, Gillott R, Wu J, Middlemass C, Weston S et al. ( 2019 ) . ‘Caveat emptor’: the cautionary tale of endocarditis and the potential pitfalls of clinical coding data—an electronic health records study . BMC Medicine vol. 17 , ( 1 ) Article 169 ,

Straw S, Baig MW, Gillott R, Wu J, Witte KK, O’regan DJ, Sandoe JAT ( 2019 ) . Long-term Outcomes Are Poor in Intravenous Drug Users Following Infective Endocarditis, Even After Surgery . Clinical Infectious Diseases vol. 71 , ( 3 ) 564 - 571 .

Godazandeh K, Martinez Sosa S, Wu J, Zakrzewska JM ( 2019 ) . Trigeminal neuralgia: Comparison of characteristics and impact in patients with or without multiple sclerosis . Multiple Sclerosis and Related Disorders vol. 34 , 41 - 46 .

Gul HL, Eugenio G, Rabin T, Burska A, Parmar R, Wu J, Ponchel F, Emery P ( 2019 ) . Defining remission in rheumatoid arthritis: does it matter to the patient? A comparison of multi-dimensional remission criteria and patient reported outcomes . Rheumatology Article kez330 ,

Wu J, Keeley A, Mallen C, Morgan AW, Pujades-Rodriguez M ( 2019 ) . Incidence of infections associated with oral glucocorticoid dose in people diagnosed with polymyalgia rheumatica or giant cell arteritis: a cohort study in England . Canadian Medical Association Journal vol. 191 , ( 25 ) E680 - E688 .

Ali N, Baig W, Wu J, Blackman D, Gillott R, Sandoe J ( 2019 ) . 129 Prosthetic valve endocarditis following transcatheter aortic valve implantation – experience from a UK centre . Valve Disease/Pericardial Disease/Cardiomyopathy . Conference: British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019A105 - A106 .

Straw S, Baig W, Wu J, Sandoe J ( 2019 ) . 130 Fever in an intravenous drug user: if it isn’t endocarditis then what is it? . Valve Disease/Pericardial Disease/Cardiomyopathy . Conference: British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019A106 - A106 .

Orlowski A, Wu JH, Wilkins J, Smith W ( 2019 ) . CV4 BUDGET IMPACT OF CHANGING ORAL ANTICOAGULANT PRESCRIBING TO PREVENT ATRIAL-FIBRILLATION-RELATED STROKE IN ENGLAND . Value in Health . vol. 22 , S38 - S39 .

Orlowski A, Wu JH, Wilkins J, Smith W ( 2019 ) . PCV113 DIFFERENCE-IN-DIFFERENCES ANALYSIS OF THE IMPACT OF ORAL ANTICOAGULANT PRESCRIBING ON INCIDENCE OF ATRIAL-FIBRILLATION-RELATED STROKE . Value in Health . vol. 22 , S139 - S139 .

( 2019 ) . Association between central obesity and tooth loss in the non‐obese people: Results from the continuous National Health and Nutrition Examination Survey (<scp>NHANES</scp>) 1999–2012 . Journal of Clinical Periodontology vol. 46 , ( 4 ) 430 - 437 .

( 2019 ) . Cognitive function and oral health among ageing adults . Community Dentistry and Oral Epidemiology vol. 47 , ( 3 ) 259 - 266 .

Smyth AG, Wu J ( 2019 ) . Cleft Palate Outcomes and Prognostic Impact of Palatal Fistula on Subsequent Velopharyngeal Function—A Retrospective Cohort Study . The Cleft Palate Craniofacial Journal vol. 56 , ( 8 ) 1008 - 1012 .

( 2019 ) . The effectiveness of self‐management interventions in adults with chronic orofacial pain: A systematic review, meta‐analysis and meta‐regression . European Journal of Pain vol. 23 , ( 5 ) 849 - 865 .

( 2019 ) . Association between time of hospitalization with acute myocardial infarction and in-hospital mortality . European Heart Journal vol. 40 , ( 15 ) 1214 - 1221 .

Douiyeb S, Sigaloff K, Samson A, de la Court J, van der Vaart T, Baig W, Wu J, Gillot R et al. ( 2019 ) . Six versus four weeks of intravenous antibiotic treatment for staphylococcus aureus endocarditis: a pilot study . EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY . vol. 75 , S15 - S15 .

Rao VP, Wu J, Gillott R, Baig MW, Kaul P, Sandoe JAT ( 2018 ) . Impact of the duration of antibiotic therapy on relapse and survival following surgery for active infective endocarditis . European Journal of Cardio-Thoracic Surgery vol. 55 , ( 4 ) 760 - 765 .

Cowan JC, Wu J, Hall M, Orlowski A, West RM, Gale CP ( 2018 ) . A 10 year study of hospitalized atrial fibrillation-related stroke in England and its association with uptake of oral anticoagulation . European Heart Journal vol. 39 , ( 32 ) 2975 - 2983 .

Soldani F, Wu J ( 2018 ) . School based oral health education . Evidence-Based Dentistry vol. 19 , ( 2 ) 36 - 37 .

Zakrzewska JM, Wu J, Brathwaite TS-L ( 2018 ) . A Systematic Review of the Management of Trigeminal Neuralgia in Patients with Multiple Sclerosis . World Neurosurgery vol. 111 , 291 - 306 .

Duale JMJ, Patel YA, Wu J, Hyde TP ( 2018 ) . A Systematic Review and Meta -Analysis of Baseline Ohip-Edent Scores . EUROPEAN JOURNAL OF PROSTHODONTICS AND RESTORATIVE DENTISTRY vol. 26 , ( 1 ) 17 - 23 .

Hussain N, Jabbar H, Hayati M, Wu J, Hyde TP ( 2018 ) . Surveys of Current Teaching and Practice for Impressions for Complete Dentures . EUROPEAN JOURNAL OF PROSTHODONTICS AND RESTORATIVE DENTISTRY vol. 26 , ( 2 ) 86 - 93 .

Zakrzewska JM, Wu J, Mon-Williams M, Phillips N, Pavitt SH ( 2017 ) . Evaluating the impact of trigeminal neuralgia . Pain vol. 158 , ( 6 ) 1166 - 1174 .

Davda K, Osnes C, Dillon S, Wu J, Hyde P, Keeling A ( 2017 ) . An Investigation into the Trueness and Precision of Copy Denture Templates Produced by Rapid Prototyping and Conventional Means . EUROPEAN JOURNAL OF PROSTHODONTICS AND RESTORATIVE DENTISTRY vol. 25 , ( 4 ) 186 - 192 .

( 2016 ) . Editor’s Choice - Impact of initial hospital diagnosis on mortality for acute myocardial infarction: A national cohort study . European Heart Journal: Acute Cardiovascular Care vol. 7 , ( 2 ) 139 - 148 .

Almiron-Roig E, Tsiountsioura M, Lewis HB, Wu J, Solis-Trapala I, Jebb SA ( 2015 ) . Large portion sizes increase bite size and eating rate in overweight women . Physiology &amp; Behavior vol. 139 , 297 - 302 .

( 2013 ) . Erratum: The population prevalence of Down’s syndrome in England and Wales in 2011 . European Journal of Human Genetics vol. 21 , ( 9 ) 1033 - 1034 .

( 2013 ) . Erratum: Trends in maternal age distribution and the live birth prevalence of Down’s syndrome in England and Wales: 1938–2010 . European Journal of Human Genetics vol. 21 , ( 9 ) 1032 - 1033 .

( 2013 ) . Survival of trisomy 18 (Edwards syndrome) and trisomy 13 (Patau Syndrome) in England and Wales: 2004–2011 . American Journal of Medical Genetics Part A vol. 161 , ( 10 ) 2512 - 2518 .

( 2013 ) . Patient Factors Influencing the Prescribing of Lipid Lowering Drugs for Primary Prevention of Cardiovascular Disease in UK General Practice: A National Retrospective Cohort Study . PLoS ONE vol. 8 , ( 7 ) e67611 - e67611 .

( 2013 ) . The population prevalence of Down's syndrome in England and Wales in 2011 . EUROPEAN JOURNAL OF HUMAN GENETICS vol. 21 , ( 9 ) 1016 - 1019 .

( 2013 ) . Trends in maternal age distribution and the live birth prevalence of Down's syndrome in England and Wales: 1938-2010 . EUROPEAN JOURNAL OF HUMAN GENETICS vol. 21 , ( 9 ) 943 - 947 .

( 2012 ) . Case-mix adjusted hospital mortality is a poor proxy for preventable mortality: a modelling study . BMJ Quality &amp; Safety vol. 21 , ( 12 ) 1052 - 1056 .

( 2012 ) . A systematic review evaluating the relationship between progression free survival and post progression survival in advanced ovarian cancer . Gynecologic Oncology vol. 125 , ( 2 ) 493 - 499 .

( 2012 ) . Weber's law implies neural discharge more regular than a Poisson process .

( 2009 ) . Impact of environmental inputs on reverse-engineering approach to network structures . BMC Systems Biology vol. 3 , ( 1 ) Article 113 ,

( 2009 ) . The Role of Background Statistics in Face Adaptation . The Journal of Neuroscience vol. 29 , ( 39 ) 12035 - 12044 .

( 2008 ) . Uncovering Interactions in the Frequency Domain . PLoS Computational Biology vol. 4 , ( 5 ) e1000087 - e1000087 .

( 2008 ) . Detecting causality between different frequencies . Journal of Neuroscience Methods vol. 167 , ( 2 ) 367 - 375 .

( 2007 ) . A novel approach to detect hot-spots in large-scale multivariate data . BMC Bioinformatics vol. 8 , ( 1 ) Article 331 ,

( 2007 ) . Detecting correlation changes in electrophysiological data . Journal of Neuroscience Methods vol. 161 , ( 1 ) 155 - 165 .

Wu J, Mackie SL, Pujades-Rodriguez M . Glucocorticoid Dose-Dependent Risk of Type 2 Diabetes in Six Immune-Mediated Inflammatory Diseases: A Population-Based Cohort Analysis .

Mu L, Larvin H, Nadarajah R, Gale C, Wu J . Long-term cardiovascular risks after atrial fibrillation diagnosis: A systematic review and meta-analysis . BMJ Heart

Nakao YM, Nakao K, Wu J, Nadarajah R, Camm J, Gale CP . Risks and Benefits of Oral Anticoagulants for Stroke Prophylaxis in Atrial Fibrillation According to Body Mass Index: Nationwide Cohort Study of Primary Care Records in England .