Publications: DR Priyanthi Dias

Dias P, Walshaw E, Flatau S, O'Grady E, Hopkins PM, Garvey LH, Littlejohns A, Rousseau N et al. ( 2025 ) . Penicillin allergy risk stratification tool for use by non‐allergists in the peri‐operative setting: an agreement study and qualitative process evaluation . Anaesthesia

Giannas E, Patel A, Dias P, Heath RJ, Sinclair R, Surman K, Milton A, Middleditch A et al. ( 2025 ) . Perioperative management of renin–angiotensin system inhibitors in patients undergoing elective major noncardiac surgery: a mixed model investigation using systematic review, meta-analysis, multicentre service evaluation, and national survey . British Journal of Anaesthesia vol. 135 , ( 4 ) 861 - 869 .

Janssen H, Dias P, Ahuja S, Alharbi S, Hiller L, Khan K, Iyer K, Sundar A et al. ( 2025 ) . Accuracy of continuous glucose monitoring during noncardiac surgery: a prospective, blinded observational multicentre cohort study . British Journal of Anaesthesia vol. 135 , ( 4 ) 912 - 919 .

Abbott TEF, Watson S-L, Begum S, Dias P, Haviland JS, Glasbey J, Ismail L, Love S et al. ( 2025 ) . Platform trials—an emerging methodology for perioperative medicine: a narrative review . Perioperative Medicine vol. 14 , ( 1 )

Janssen H, Dias P, Hiller L, Hewson R, Pearse RM, Oliver NS, Jhanji S, Ackland GL et al. ( 2025 ) . Glucose variability and mode of anaesthesia in major noncardiac surgery (GlucoVITAL): study protocol for a randomised controlled trial . BJA Open vol. 14 ,

investigators E, Ali A, Noblett J, Usman N, Wray S, Blake H, del Arroyo AG, Abbott TEF et al. ( 2025 ) . Interleukin-1 receptor antagonist polymorphisms in women receiving epidural analgesia who develop maternal intrapartum fever: a prospective, multicentre Mendelian randomised study . British Journal of Anaesthesia vol. 135 , ( 1 ) 134 - 140 .

Pinto BB, Shelley B, Dias P, Begum S, Ennahdi-Elidrissi F, Abbott TEF, Hewson R, Patel A et al. ( 2025 ) . Targeted heart rate control using the funny current inhibitor ivabradine to reduce morbidity in patients undergoing noncardiac surgery: study protocol for a phase 2a, triple-blind, placebo-controlled randomised trial . BJA Open vol. 13 ,

Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2025 ) . Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial . EClinicalMedicine vol. 81 ,

Janssen HJ, Pearse R, Giannas E, Patel A, Dias P, ABBOTT T, Ackland G ( 2024 ) . Perioperative management of renin-angiotensin aldosterone-system inhibitors in patients undergoing elective major non-cardiac surgery: A mixed model investigation of systematic review, meta-analysis, multicentre service evaluation and national survey .

Gutierrez Del Arroyo A, ABBOTT T, Kapil V, Ackland G ( 2024 ) . Preoperative activation of the renineangiotensin system and myocardial injury in noncardiac surgery: exploratory mechanistic analysis of the SPACE randomised controlled trial . British Journal of Anaesthesia

Pearse R, Hamborg T ( 2024 ) . Cardiac output-guided haemodynamic therapy for patients undergoing major gastrointestinal surgery: the OPTIMISE II randomised clinical trial . British Medical Journal

Crowther M, Dyer RA, Bishop DG, Bulamba F, Maswime S, Pearse RM, Biccard BM, Investigators OBOTAPFPACCR ( 2024 ) . Cross-Sectional Survey to Assess Hospital System Readiness for Hemorrhage During and After Cesarean Delivery in Africa . Anesthesia & Analgesia vol. 141 , ( 3 ) 456 - 463 .

Giannas E, Dias P, Janssen H, Ackland G, Pearse R, Abbott T ( 2024 ) . Clinical management of stopping or continuing perioperative angiotensin II converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of clinical opinion . BJA Open vol. 12 , 100313 - 100313 .

Watson S-L, Fowler AJ, Dias P, Biccard B, Wan YI, Pearse RM, Abbott TEF ( 2024 ) . The lifetime risk of surgery in England: a nationwide observational cohort study . British Journal of Anaesthesia vol. 133 , ( 4 ) 768 - 775 .

del Arroyo AG, Patel A, Abbott TEF, Begum S, Dias P, Somanath S, Middleditch A, Cleland S et al. ( 2024 ) . Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin–angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial . British Journal of Anaesthesia vol. 132 , ( 5 ) 857 - 866 .

Booth J, Fowler AJ, Pearse R, Dias P, Wan YI, Witton R, Abbott TEF ( 2024 ) . Dental Surgical Activity in Hospitals during COVID-19: A Nationwide Observational Cohort Study . JDR Clinical & Translational Research vol. 9 , ( 4 ) 387 - 397 .

Ackland GL, Martin T, Joseph M, Dias P, Hameed R, del Arroyo AG, Hewson R, Abbott TEF et al. ( 2023 ) . Transauricular nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: Protocol for a phase 2A, proof-of-concept, sham-controlled randomised trial . PLOS ONE vol. 18 , ( 12 )

Ackland G, Abbott T, Pearse R ( 2023 ) . Discontinuation vs. continuation of renin–angiotensin system inhibition before non-cardiac surgery: the SPACE trial . European Heart Journal Article ehad716 ,

Edwards MR, Forbes G, Walker N, Morton DG, Mythen MG, Murray D, Anderson I, Mihaylova B et al. ( 2023 ) . Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery . Trials vol. 24 , ( 1 )

Bedwell GJ, Dias P, Hahnle L, Anaeli A, Baker T, Beane A, Biccard BM, Bulamba F et al. ( 2022 ) . Barriers to Quality Perioperative Care Delivery in Low- and Middle-Income Countries: A Qualitative Rapid Appraisal Study . Anesthesia & Analgesia vol. 135 , ( 6 ) 1217 - 1232 .

Fowler AJ, Dias P, Hui S, Cashmore R, Laloo R, Ahmad AN, Gillies MA, Wan YI et al. ( 2022 ) . Liberal or restrictive antimicrobial prophylaxis for surgical site infection: systematic review and meta-analysis of randomised trials . British Journal of Anaesthesia vol. 129 , ( 1 ) 104 - 113 .

Dias P, Patel A, Rook W, Edwards MR, Pearse RM, Abbott TEF, SAPPHIRE Investigators ( 2021 ) . Contemporary use of antimicrobial prophylaxis for surgical patients: An observational cohort study . Eur J Anaesthesiol

Pearse R, ABBOTT T, Patel A, Dias P, Hewson R, Stephens T ( 2021 ) . Postoperative continuous positive airways pressure (CPAP) to prevent pneumonia, re-intubation and death after major abdominal surgery: An international randomised trial . The Lancet Respiratory Medicine

ABBOTT T, Fowler A, Dobbs T, Gibson J, Shahid T, Dias P, Akbari A, Whitaker I et al. ( 2021 ) . Mortality after surgery with SARS-CoV-2 infection in England: A population-wide epidemiological study . BJA: British Journal of Anaesthesia

Abbott TEF, Fowler AJ, Dobbs TD, Gibson J, Shahid T, Dias P, Akbari A, Whitaker IS et al. ( 2021 ) . Mortality after surgery with SARS-CoV-2 infection in England: A population-wide epidemiological study . MedRxiv

Fowler AJ, Dias P, Hui S, Cashmore R, Laloo R, Ahmad AN, Gillies MA, Wan YI et al. ( 2020 ) . Liberal <i>Versus</i> Restrictive Antimicrobial Prophylaxis for Surgical Site Infection: Systematic Review and Meta-Analysis of Randomised Trials .

Short TG, Campbell D, Frampton C, Chan MTV, Myles PS, Corcoran TB, Sessler DI, Mills GH et al. ( 2019 ) . Anaesthetic depth and complications after major surgery: an international, randomised controlled trial . The Lancet vol. 394 , ( 10212 ) 1907 - 1914 .

Edwards MR, Forbes G, MacDonald N, Berdunov V, Mihaylova B, Dias P, Thomson A, Grocott MP et al. ( 2019 ) . Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery . BMJ Open vol. 9 , ( 1 ) e023455 - e023455 .

Kane C, Gorelik J ( 2015 ) . Abstract 19960: Human Cardiac Fibroblasts Increase SR-Dependency of Induced Pluripotent Stem Cell-Derived Cardiomyocyte Calcium Handling by Increasing SR Calcium Uptake and SERCA2a Expression via Direct Physical Contact . Circulation vol. 132 , ( suppl_3 )

Cartledge JE, Kane C, Dias P, Tesfom M, Al Ayoubi S, Chester A, Camelliti P ( 2015 ) . Functional crosstalk between cardiac fibroblasts and adult cardiomyocytes by soluble mediators . Cardiovascular Research vol. 105 , ( 3 ) 260 - 270 .

Kane C, Dias P, Helen N, Trantidou T ( 2014 ) . 267Direct contact between human cardiac fibroblasts and human induced pluripotent stem cell-derived cardiomyocytes counteracts changes in calcium cycling induced by soluble mediators . Cardiovascular Research vol. 103 , ( suppl_1 ) s48 - s48 .

Alayoubi S, Al-Aidarous S, Ricardo CP, Dias P, Zaman J, Kane C, Yacoub M ( 2014 ) . P379Slowed conduction velocity in spontaneously hypertensive rat hearts is due to disease related remodelling . Cardiovascular Research vol. 103 , ( suppl_1 ) s69 - s69 .

Humphrey E, Trantidou T, Kane C, Dias P, Peters NS ( 2014 ) . P396Improved calcium cycling is associated with microtubule reorganisation in anisotropic cardiomyocyte cultures . Cardiovascular Research vol. 103 , ( suppl_1 ) s73 - s73 .

Dias P, Desplantez T, El-Harasis MA, Chowdhury RA, Ullrich ND, de Diego AC, Peters NS ( 2014 ) . Characterisation of Connexin Expression and Electrophysiological Properties in Stable Clones of the HL-1 Myocyte Cell Line . PLOS ONE vol. 9 , ( 2 )

Ibrahim M, Navaratnarajah M, Siedlecka U, Rao C, Dias P, Moshkov AV, Yacoub MH ( 2014 ) . Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca2+‐induced Ca2+release in a rodent model of heart failure . European Journal of Heart Failure vol. 14 , ( 6 ) 571 - 580 .

Kane C, Cartledge J, Dias P, Terracciano C ( 2014 ) . 17 Cardiomyocytes Influence Fibroblast Proliferation and α-Smooth Muscle Actin Expression via the Secretion of Paracrine Mediators . Heart vol. 100 , ( Suppl 1 )

Dias P, Navaratnarajah M, Alayoubi S, Cartledge JE, Starke R, Sarathchandra P, Latif N ( 2014 ) . 9 Ivabradine Alters Fibroblast Number and Transforming Growth Factor beta 1 Expression in Heart Failure . Heart vol. 100 , ( Suppl 1 )

Alayoubi S, Ricardo CP, Zaman J, Dias P, Camelliti P ( 2014 ) . Electrophysiological and Structural Left Ventricle Remodelling in Spontaneously Hypertensive Rat Hearts: A Multicellular Study . Biophysical Journal vol. 106 , ( 2 )

Dias P, Navaratnarajah M, Alayoubi S, Kane C, Felkin LE, Cartledge JE, Jayaratne N, Yacoub MH ( 2014 ) . Ivabradine Reduces α-Smooth Muscle Actin Expression, Proliferation and Collagen Production in Human Cardiac Fibroblasts . Biophysical Journal vol. 106 , ( 2 )

Dias P ( 2013 ) . Hyperpolarization‐Activated Cyclic Nucleotide‐Gated Channels and Ventricular Arrhythmias in Heart Failure: A Novel Target for Therapy? . Journal of the American Heart Association vol. 2 , ( 3 )

Ibrahim M, Siedlecka U, Rao C, Dias P, Moshkov A, Yacoub M ( 2013 ) . Mechanical unloading reverses transverse tubule remodelling and normalises local calcium-induced calcium release in a rodent model of heart failure . The Lancet vol. 381 ,

Navaratnarajah M, Ibrahim M, Siedlecka U, van Doorn C, Shah A, Sarathchandra P ( 2012 ) . Influence of ivabradine on reverse remodelling during mechanical unloading . Cardiovascular Research vol. 97 , ( 2 ) 230 - 239 .

Navaratnarajah M, Ibrahim M, Siedlecka U, Gandhi A, Shah A, Van Doorn C, Yacoub MH ( 2011 ) . Abstract 9342: Ivabradine Reduces Interstitial Fibrosis and Enhances the Recovery of Cardiomyocyte Excitation-Contraction Coupling Produced by Mechanical Unloading . Circulation vol. 124 , ( suppl_21 )

Navaratnarajah M, van Doorn C, Siedlecka U, Ibrahim M, Shah A, Gandhi A ( 2011 ) . Abstract 9970: Combined Clenbuterol and Metoprolol Therapy Improves Cardiac Function and Calcium Handling in a Rodent Model of Heart Failure, but Does Not Prevent Myocardial Atrophy or Enhance Myocyte Recovery Associated with Mechanical Unloading . Circulation vol. 124 , ( suppl_21 )

del Arroyo AG, Abbott TEF, Patel A, Begum S, Dias P, Brealey D, Pearse RM, Kapil V et al. . Preoperative activation of the Renin–Angiotensin system and myocardial injury in noncardiac surgery: Post Hoc Analysis of the SPACE randomised controlled Trial .

Pearse R . The African Critical Illness Outcomes Study (ACIOS): A point prevalence study of critical illness in 22 nations in Africa . The Lancet