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Research

Publications: DR Sindhuja Sridharan

Uechi H, Sridharan S, Nijssen J, Bilstein J, Iglesias-Artola JM, Kishigami S, Casablancas-Antras V, Poser I et al. ( 2025 ) . Small-molecule dissolution of stress granules by redox modulation benefits ALS models . Nature Chemical Biology vol. 21 , ( 10 ) 1577 - 1588 .
Etibor TA, Vale-Costa S, Sridharan S, Brás D, Becher I, Mello VH, Ferreira F, Alenquer M et al. ( 2023 ) . Defining basic rules for hardening influenza A virus liquid condensates . eLife vol. 12 ,
Zhang X, Sridharan S, Zagoriy I, Oegema CE, Ching C, Pflaesterer T, Fung HKH, Becher I et al. ( 2023 ) . Molecular mechanisms of stress-induced reactivation in mumps virus condensates . Cell vol. 186 , ( 9 ) 1877 - 1894.e27 .
Le Sueur C, Hammarén HM, Sridharan S, Savitski MM ( 2022 ) . Thermal proteome profiling: Insights into protein modifications, associations, and functions . Current Opinion in Chemical Biology vol. 71 ,
Sridharan S, Hernandez-Armendariz A, Kurzawa N, Potel CM, Memon D, Beltrao P, Bantscheff M, Huber W et al. ( 2022 ) . Systematic discovery of biomolecular condensate-specific protein phosphorylation . Nature Chemical Biology vol. 18 , ( 10 ) 1104 - 1114 .
Kurzawa N, Becher I, Sridharan S, Franken H, Mateus A, Anders S, Bantscheff M, Huber W et al. ( 2021 ) . Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles . Nature Communications vol. 12 , ( 1 )
Kurzawa N, Becher I, Sridharan S, Franken H, Mateus A, Anders S, Bantscheff M, Huber W et al. ( 2020 ) . A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles . Nature Communications vol. 11 , ( 1 )
Määttä TA, Rettel M, Sridharan S, Helm D, Kurzawa N, Stein F, Savitski MM ( 2020 ) . Aggregation and disaggregation features of the human proteome . Molecular Systems Biology vol. 16 , ( 10 )
Mateus A, Kurzawa N, Becher I, Sridharan S, Helm D, Stein F, Typas A, Savitski MM ( 2020 ) . Thermal proteome profiling for interrogating protein interactions . Molecular Systems Biology vol. 16 , ( 3 )
Sridharan S, Kurzawa N, Werner T, Günthner I, Helm D, Huber W, Bantscheff M, Savitski MM ( 2019 ) . Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP . Nature Communications vol. 10 , ( 1 )
Sridharan S, Kini RM ( 2018 ) . Decoding the molecular switches of natriuretic peptides which differentiate its vascular and renal functions . Biochemical Journal vol. 475 , ( 2 ) 399 - 413 .
McCleary RJR, Sridharan S, Dunstan NL, Mirtschin PJ, Kini RM ( 2016 ) . Proteomic comparisons of venoms of long-term captive and recently wild-caught Eastern brown snakes (Pseudonaja textilis) indicate venom does not change due to captivity . Journal of Proteomics vol. 144 , 51 - 62 .
Sridharan S, Kini RM ( 2015 ) . Tail wags the dog: activity of krait natriuretic peptide is determined by its C-terminal tail in a natriuretic peptide receptor-independent manner . Biochemical Journal vol. 469 , ( 2 ) 255 - 266 .