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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: MISS Molly Guscott

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Lumeau A, Guscott MA, Pere NM, Nichols I, Werner B, Dusetti N, McClelland SE ( 2025 ) . Abstract B129: Tracking genome evolution and chemoresistance in pancreatic cancer . Cancer Research vol. 85 , ( 18_Supplement_3 ) b129 - b129 .
Deenonpoe R, Guscott MA, Watcharadetwittaya S, McNeill IL, Moralli D, Shaikh N, McClelland SE ( 2025 ) . Chromosomal instability and genomic alterations in cholangiocarcinoma from Northeastern Thailand . The Journal of Pathology vol. 267 , ( 3 ) 261 - 274 .
Khan MA, Hall A, Guscott M, Bakali N, McClelland S, Graham T, Lockley M ( 2025 ) . 29P BRCA1 reversion mutations confer a fitness benefit to PARP inhibitor-resistant subclones in high grade serous ovarian cancer models . ESMO Open vol. 10 ,
( 2024 ) . IL-33 is associated with alveolar dysfunction in patients with viral lower respiratory tract disease . Mucosal Immunology vol. 18 , ( 2 ) 312 - 325 .
Guscott MA, McClelland SE ( 2024 ) . Experimental evolution of cancer chromosomal changes . Nature Genetics vol. 56 , ( 5 ) 743 - 745 .
Zheng J, Bewicke-Copley F, Vermeulen C, Casado P, Kaya F, Demeulemeester J, Guscott M, Krizsán S et al. ( 2023 ) . Allele-Specific Expression of Leukemia Genes Is Associated with Pathogenicity in Poor Risk AML . Blood vol. 142 , ( Supplement 1 )
Tovini L, Johnson SC, Guscott MA, Andersen AM, Spierings DCJ, Wardenaar R, Foijer F, McClelland SE ( 2023 ) . Targeted assembly of ectopic kinetochores to induce chromosome‐specific segmental aneuploidies . The EMBO Journal vol. 42 , ( 10 )
Guscott M, Saha A, Maharaj J, McClelland SE ( 2022 ) . The multifaceted role of micronuclei in tumour progression: A whole organism perspective . The International Journal of Biochemistry & Cell Biology vol. 152 ,
( 2018 ) . Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage . Scientific Reports vol. 8 , ( 1 )
Lumeau A, Pfuderer P, De Angelis S, Scarth J, Guscott M, Shaikh N, Copley F, Gerdes H et al. . High levels of DNA replication initiation factors indicate ATRi sensitivity via excessive origin firing .
Guscott MA, Gómez-Peregrina D, Andersen AM, Soliman TN, Horrach CV, Bakker B, Spierings DCJ, Wardenaar R et al. . Tracking genome evolution in single cell clones reveals the rates and features of copy number alterations generated by ongoing chromosomal instability in cancer .
Bojko J, Flynn B, Aschenbrenner B, Howard A, Lay E, Aschenbrenner B, Guscott M, Catalan S et al. . YAP engages RIF1 to dampen replication stress-induced DNA damage in human squamous cell carcinoma .
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