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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: DR Alex Clark

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( 2024 ) . Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons . Stem Cell Reports vol. 19 , ( 7 ) 957 - 972 .
( 2024 ) . Advances and challenges in modeling inherited peripheral neuropathies using iPSCs . Experimental & Molecular Medicine vol. 56 , ( 6 ) 1348 - 1364 .
( 2023 ) . A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons . Science Translational Medicine vol. 15 , ( 716 ) Article eadh3839 ,
( 2023 ) . Inhibition of sensory neuron driven acute, inflammatory, and neuropathic pain using a humanised chemogenetic system .
( 2021 ) . An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions . Cell Reports Medicine vol. 2 , ( 7 ) Article 100345 , 100345 - 100345 .
( 2021 ) . Corrigendum to: Molecular and cellular correlates of human nerve regeneration: <i>ADCYAP1</i>/PACAP enhance nerve outgrowth . Brain vol. 144 , ( 5 ) e49 - e49 .
( 2020 ) . Molecular and cellular correlates of human nerve regeneration: ADCYAP1/PACAP enhance nerve outgrowth . Brain vol. 143 , ( 7 ) 2009 - 2026 .
( 2020 ) . Establishing Myelinating Cocultures Using Human iPSC-Derived Sensory Neurons to Investigate Axonal Degeneration and Demyelination . Methods in Molecular Biology , Springer US
( 2019 ) . Defining the Functional Role of NaV1.7 in Human Nociception . Neuron vol. 101 , ( 5 ) 905 - 919.e8 .
( 2018 ) . Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury . Pain vol. 160 , ( 2 ) 463 - 485 .
( 2018 ) . Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro . Neurobiology of Disease vol. 117 , 1 - 14 .
( 2018 ) . Functional imaging in microfluidic chambers reveals sensory neuron sensitivity is differentially regulated between neuronal regions . Pain vol. 159 , ( 7 ) 1413 - 1425 .
( 2018 ) . Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability . Neuron vol. 97 , ( 4 ) 806 - 822.e10 .
( 2017 ) . Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source . Brain vol. 140 , ( 10 ) 2570 - 2585 .
( 2017 ) . Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination . Brain vol. 140 , ( 4 ) 898 - 913 .
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