Publications: P Benjamin Jacobs

Zöllner J, Orazumbekova B, Hodgson S, van Heel DA, Akhtar S, Anwar M, Asgar O, Ashraf S et al. ( 2025 ) . Understanding the potential contribution of polygenic risk scores to the prediction of gestational and type 2 diabetes in women from British Pakistani and Bangladeshi groups: a cohort study in Genes and Health . AJOG Global Reports vol. 5 , ( 2 ) Article 100457 , 100457 - 100457 .

Venkatesh SS, Wittemans LBL, Palmer DS, Baya NA, Ferreira T, Hill B, Lassen FH, Parker MJ et al. ( 2025 ) . Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum . Nature Genetics vol. 57 , ( 5 ) 1107 - 1118 .

Yngvadottir B, Richman L, Andreou A, Woodley J, Luharia A, Lim D, Maher ER, Marciniak SJ ( 2025 ) . Inherited predisposition to pneumothorax: estimating the frequency of Birt-Hogg-Dub� syndrome from genomics and population cohorts . Thorax vol. 80 , ( 8 ) 553 - 555 .

( 2025 ) . Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores . Scientific Reports vol. 15 , ( 1 ) Article 1168 ,

Hamilton F, Schurz H, Yates TA, Gilchrist JJ, Möller M, Naranbhai V, Ghazal P, Timpson NJ et al. ( 2025 ) . Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study . The Lancet Microbe vol. 6 , ( 1 ) Article 100922 , 100922 - 100922 .

Jacobs BM, Gasperi C, Kalluri SR, Al-Najjar R, McKeon MO, Else J, Pukaj A, Held F et al. ( 2025 ) . Single-cell analysis of cerebrospinal fluid reveals common features of neuroinflammation . Cell Reports Medicine vol. 6 , ( 1 ) Article 101733 , 101733 - 101733 .

Hodgson S, Williamson A, Bigossi M, Stow D, Jacobs BM, Samuel M, Gafton J, Zöllner J et al. ( 2024 ) . Genetic basis of early onset and progression of type 2 diabetes in South Asians . Nature Medicine vol. 31 , ( 1 ) 323 - 331 .

Talaei M, Waters S, Portas L, Jacobs BM, Dodd JW, Marshall CR, Minelli C, Shaheen SO ( 2024 ) . Lung development genes, adult lung function and cognitive traits . Brain Communications vol. 6 , ( 6 ) Article fcae380 ,

Jacobs BM, Stow D, Hodgson S, Zöllner J, Samuel M, Kanoni S, Bidi S, Akhtar S et al. ( 2024 ) . Genetic architecture of routinely acquired blood tests in a British South Asian cohort . Nature Communications vol. 15 , ( 1 ) Article 8929 ,

Jacobs BM, Schalk L, Tregaskis-Daniels E, Tank P, Hoque S, Peter M, Tuite-Dalton K, Witts J et al. ( 2024 ) . The relationship between ethnicity and multiple sclerosis characteristics in the United Kingdom: A UK MS Register study . Multiple Sclerosis Journal vol. 30 , ( 11-12 ) 1544 - 1555 .

Gomez EA, De Matteis R, Udomjarumanee P, Munroe PB, Dalli J ( 2024 ) . An <i>LGR6</i> frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections . Blood vol. 144 , ( 4 ) 420 - 434 .

Badenoch JB, Paris A, Jacobs BM, Noyce AJ, Marshall CR, Waters S ( 2024 ) . Neuroanatomical and prognostic associations of depression in Parkinson’s disease . Journal of Neurology, Neurosurgery &amp; Psychiatry

Venkatesh SS, Wittemans LBL, Palmer DS, Baya NA, Ferreira T, Hill B, Lassen FH, Parker MJ et al. ( 2024 ) . Genome-wide analyses identify 21 infertility loci and over 400 reproductive hormone loci across the allele frequency spectrum .

Siddiqui M, Hodgson S, Williamson A, Stow D, Jacobs B, Samuel M, Gafton J, Zöllner J et al. ( 2024 ) . Partitioned polygenic scores highlight role of beta-cell function and unfavourable fat distribution patterns in young onset type 2 diabetes in south Asians .

Jacobs BM, Schalk L, Tregaskis-Daniels E, Tank P, Hoque S, Peter M, Tuite-Dalton K, Witts J et al. ( 2024 ) . The relationship between ethnicity and Multiple Sclerosis characteristics in the United Kingdom: a UK MS Register study .

Jacobs BM, Vickaryous N, Giovannoni G, Proitsi P, Waters S, Dobson R ( 2024 ) . Plasma proteomic profiles of <scp>UK</scp> Biobank participants with multiple sclerosis . Annals of Clinical and Translational Neurology vol. 11 , ( 3 ) 698 - 709 .

Reynoso A, Torricelli R, Jacobs BM, Shi J, Aslibekyan S, Norcliffe‐Kaufmann L, Noyce AJ, Heilbron K ( 2024 ) . Gene–Environment Interactions for Parkinson's Disease . Annals of Neurology vol. 95 , ( 4 ) 677 - 687 .

Foote IF, Bandres‐Ciga S, Kim JJ, Alvarado CX, Leonard HL, Bothongo PLK, Grotzinger AD, Jacobs BM et al. ( 2023 ) . A Multivariate Genome‐Wide Association Study of the Shared Genetic Architecture Among Modifiable Risk Factors for Dementia: 590 Loci Associated with Brain Health . Alzheimer's &amp; Dementia vol. 19 , ( S22 ) Article e079738 ,

Magavern EF, Jacobs B, Warren H, Finocchiaro G, Finer S, Van Heel DA, Smedley D, Caulfield MJ ( 2023 ) . CYP2C19 genotype prevalence and association with recurrent myocardial infarction in British-South Asians treated with clopidogrel . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.2870 ,

Williams AT, Chen J, Coley K, Batini C, Izquierdo A, Packer R, Abner E, Kanoni S et al. ( 2023 ) . Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease . Nature Communications vol. 14 , ( 1 ) Article 6713 ,

Jacobs B, Stow D, Hodgson S, Zöllner J, Samuel M, Kanoni S, Bidi S, Team GAHR et al. ( 2023 ) . Genetic architecture of routinely acquired blood tests in a UK cohort of South Asian ancestry reveals ancestry-specific causal variants .

Bernard Healey SA, Giovannoni G, Noyce A, Dobson R, Jacobs BM ( 2023 ) . Impact of multiple sclerosis risk alleles on the plasma proteome . Brain vol. 147 , ( 2 ) e17 - e21 .

Hartmann S, Yasmeen S, Jacobs BM, Denaxas S, Pirmohamed M, Gamazon ER, Caulfield MJ, Hemingway H et al. ( 2023 ) . ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon . Nature Communications vol. 14 , ( 1 ) Article 6156 ,

Malawsky DS, van Walree E, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM et al. ( 2023 ) . Influence of autozygosity on common disease risk across the phenotypic spectrum . Cell vol. 186 , ( 21 ) 4514 - 4527.e14 .

Jacobs BM, Tank P, Bestwick JP, Noyce AJ, Marshall CR, Mathur R, Giovannoni G, Dobson R ( 2023 ) . Modifiable risk factors for multiple sclerosis have consistent directions of effect across diverse ethnic backgrounds: a nested case–control study in an English population-based cohort . Journal of Neurology vol. 271 , ( 1 ) 241 - 253 .

Kanai M, Andrews SJ, Cordioli M, Stevens C, Neale BM, Daly M, Ganna A, Pathak GA et al. ( 2023 ) . A second update on mapping the human genetic architecture of COVID-19 . Nature vol. 621 , ( 7977 ) E7 - E26 .

Magavern EF, Jacobs B, Warren H, Finocchiaro G, Finer S, van Heel DA, Smedley D, Caulfield MJ ( 2023 ) . CYP2C19 Genotype Prevalence and Association With Recurrent Myocardial Infarction in British–South Asians Treated With Clopidogrel . JACC: Advances vol. 2 , ( 7 ) Article 100573 , 100573 - 100573 .

LIU H, Dehestani M, Blauwendraat C, Makarious MB, Leonard H, Kim JJ, Schulte C, Noyce A et al. ( 2023 ) . Polygenic resilience inheritance modulates the penetrance of Parkinson’s disease genetic risk factors . Parkinsonism &amp; Related Disorders vol. 113 ,

Jacobs BM, Vickaryous N, Giovannoni G, Proitsi P, Waters S, Dobson R ( 2023 ) . Plasma proteomic profiles of UK Biobank participants with Multiple Sclerosis .

Reynoso A, Torricelli R, Jacobs BM, Shi J, Aslibekyan S, Kaufmann L, Noyce AJ, Heilbron K ( 2023 ) . Gene-environment interactions for Parkinson’s disease .

Jacobs BM, Daruwalla C, McKeon MO, Al-Najjar R, Simcock-Davies A, Tuite-Dalton K, Brown JWL, Dobson R et al. ( 2023 ) . Early depressive symptoms and disability accrual in Multiple Sclerosis: a UK MS Register study . Scientific Reports vol. 13 , ( 1 ) Article 8227 ,

Zöllner J, Finer S, Linton KJ, Akhtar S, Anwar M, Arciero E, Ashraf S, Bidi S et al. ( 2023 ) . Rare variant contribution to cholestatic liver disease in a South Asian population in the United Kingdom . Scientific Reports vol. 13 , ( 1 ) Article 8120 ,

Jacobs BM, Schalk L, Dunne A, Scalfari A, Nandoskar A, Gran B, Mein CA, Sellers C et al. ( 2023 ) . ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK . BMJ Open vol. 13 , ( 5 ) e071656 - e071656 .

Burley K, Fitzgibbon L, van Heel D, Vuckovic D, Mumford AD, Akhtar S, Anwar M, Arciero E et al. ( 2023 ) . PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry . Research and Practice in Thrombosis and Haemostasis vol. 7 , ( 4 ) Article 100175 , 100175 - 100175 .

Breedon JR, Marshall CR, Giovannoni G, van Heel DA, Akhtar S, Anwar M, Arciero E, Asgar O et al. ( 2023 ) . Polygenic risk score prediction of multiple sclerosis in individuals of South Asian ancestry . Brain Communications vol. 5 , ( 2 ) Article fcad041 ,

Malawsky DS, van Walree E, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM et al. ( 2023 ) . Influence of autozygosity on common disease risk across the phenotypic spectrum .

Belete D, Jacobs BM, Simonet C, Bestwick JP, Waters S, Marshall CR, Dobson R, Noyce AJ ( 2023 ) . Association Between Antiepileptic Drugs and Incident Parkinson Disease . JAMA Neurology vol. 80 , ( 2 ) 183 - 183 .

Dreyer-Alster S, Achiron A, Giovannoni G, Jacobs BM, Dobson R ( 2022 ) . No evidence for an association between alcohol consumption and Multiple Sclerosis risk: a UK Biobank study . Scientific Reports vol. 12 , ( 1 ) Article 22158 ,

Kuri A, Vickaryous N, Awad A, Jacobs BM, Dobson R ( 2022 ) . Vitamin D genetic risk scores in multiple sclerosis . Journal of Neurology vol. 270 , ( 2 ) 1030 - 1035 .

Hartmann S, Yasmeen S, Jacobs BM, Denaxas S, Pirmohamed M, Gamazon ER, Caulfield MJ, Hemingway H et al. ( 2022 ) . <i>ADRA2A</i>and<i>IRX1</i>are putative risk genes for Raynaud’s phenomenon .

Jacobs BM, Peter M, Giovannoni G, Noyce AJ, Morris HR, Dobson R ( 2022 ) . Towards a global view of multiple sclerosis genetics . Nature Reviews Neurology vol. 18 , ( 10 ) 613 - 623 .

Foote IF, Jacobs BM, Mathlin G, Watson CJ, Bothongo PLK, Waters S, Dobson R, Noyce AJ et al. ( 2022 ) . The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study . Neurobiology of Aging vol. 117 , 222 - 235 .

Jacobs B, Giovannoni G, Noyce A, Morris H, Dobson R ( 2022 ) . 121 The ADAMS project: protocol and baseline results . Journal of Neurology, Neurosurgery &amp; Psychiatry . vol. 93 , e2.74 - e2.74 .

Kuri A, Vickaryous N, Jacobs BM, Awad A, Dobson R ( 2022 ) . 134 Predictors of serum vitamin D level in multiple sclerosis . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 9 ) e2.88 - e2.88 .

Simonet C, Bestwick J, Jitlal M, Waters S, Ben-Joseph A, Mar-Shall CR, Dobson R, Jacobs BM et al. ( 2022 ) . Risk factors and Parkinson’s disease presentations in primary care in a diverse UK population . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 9 ) e2.13 - e2.13 .

Jacobs B, Ban M, Baker A, Al-Najjar R, Else J, Sawcer S ( 2022 ) . Single-cell profiling of MS CSF B cells highlights roles for TNFα and mTORC1 signalling . Journal of Neurology, Neurosurgery &amp; Psychiatry . vol. 93 , e2.177 - e2.177 .

Liu H, Dehestani M, Blauwendraat C, Makarious MB, Leonard H, Kim JJ, Schulte C, Noyce A et al. ( 2022 ) . Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors . Annals of Neurology vol. 92 , ( 2 ) 270 - 278 .

Dreyer-Alster S, Achiron A, Giovannoni G, Jacobs B, Dobson R ( 2022 ) . No evidence for an association between alcohol consumption and Multiple Sclerosis risk .

Watson C, Waters S, Jacobs B, Foote I, Dey S, Noyce A, Marshall C ( 2022 ) . 003  Neuroanatomical signatures of genetic risk for Alzheimer’s disease in healthy adults . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 6 ) A101.3 - A102 .

Jacobs B, Noyce A, Bestwick J, Belete D, Giovannoni G, Dobson R ( 2022 ) . 026  Gene-environment interactions in multiple sclerosis: a UK Biobank study . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 6 ) A21.3 - A22 .

Kuri A, Jacobs BM, Leddy S, Schmierer K, Turner B, Allen-Philbey K, Stennett A, Giovannoni G et al. ( 2022 ) . 091  Evaluation of remote assessments for multiple sclerosis in a real-world setting . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 6 ) A129.1 - A129 .

Taylor T, Jacobs B, Giovannoni G, Dobson R ( 2022 ) . 211  The prevalence and characteristics of multiple sclerosis-associated uveitis in UK biobank . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 6 ) A74.2 - A74 .

Jensen M, Jacobs B, Dobson R, Bandres-Ciga S, Blauwendraat C, Schrag A, Noyce A ( 2022 ) . Lower lymphocyte count is associated with increased risk of Parkinson’s disease . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 6 ) A94.3 - A95 .

Belete D, Jacobs BM, Bestwick JP, Dobson R, Hardy J, Giovannoni G, Lees A, Schrag A et al. ( 2022 ) . Parkinson’s disease determinants, prediction and gene-environment interac- tions: a UK Biobank study . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 6 ) A7.3 - A8 .

Watson CJ, Waters S, Jacobs BM, Foote IF, Dey S, Noyce AJ, Hardy CJD, Marshall CR ( 2022 ) . Speech-in-noise perception is a marker of preclinical Alzheimer’s disease . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 93 , ( 6 ) A91.1 - A91 .

Hone L, Jacobs BM, Marshall C, Giovannoni G, Noyce A, Dobson R ( 2022 ) . Age-specific effects of childhood body mass index on multiple sclerosis risk . Journal of Neurology vol. 269 , ( 9 ) 5052 - 5060 .

Simonet C, Bestwick J, Jitlal M, Waters S, Ben-Joseph A, Marshall CR, Dobson R, Marrium S et al. ( 2022 ) . Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population . JAMA Neurology vol. 79 , ( 4 ) 359 - 359 .

Hone L, Giovannoni G, Dobson R, Jacobs BM ( 2022 ) . Predicting Multiple Sclerosis: Challenges and Opportunities . Frontiers in Neurology vol. 12 , Article 761973 ,

Waters S, Watson C, Jacobs BM, Foote IF, Dey S, Noyce AJ, Marshall CR ( 2022 ) . Neuroanatomical signatures of genetic risk for Alzheimer's disease in healthy adults . Alzheimer's &amp; Dementia vol. 17 , ( S4 ) Article e054577 ,

Else J, Jacobs B, Al-Najjar R, McKeon M, Baker A, Ban M, Sawcer S ( 2022 ) . Exploring the role of expanded tandem repeat sequences in multiple sclerosis progression . MULTIPLE SCLEROSIS JOURNAL . vol. 28 , 759 - 759 .

Breedon J, Marshall C, Van Heel D, Jacobs B, Dobson R ( 2022 ) . Limited cross-ancestry portability of european-derived multiple sclerosis polygenic risk scores: a study in ∼50,000 individuals of south asian ancestry from the Genes & Health cohort . MULTIPLE SCLEROSIS JOURNAL . vol. 28 , 224 - 224 .

Jacobs BM, Watson C, Marshall C, Noyce A, Dobson R ( 2022 ) . No evidence for association between polygenic risk of multiple sclerosis and MRI phenotypes in ∼30,000 healthy adult UK Biobank participants . MULTIPLE SCLEROSIS JOURNAL vol. 28 , ( 10 ) Article ARTN 13524585221075744 , 1656 - 1657 .

Whitford VL, Waters S, Jacobs B, Burgess LC, Tank P, Marshall C, Dobson R ( 2022 ) . Patterns and risks for cognitive impairment in multiple sclerosis: a UK biobank study . MULTIPLE SCLEROSIS JOURNAL . vol. 28 , 458 - 458 .

Gasperi C, Jacobs B, Ban M, McKeon M, Al-Najjar R, Baker A, Else J, Pukaj A et al. ( 2022 ) . The transcriptomic and clonal landscape of Multiple Sclerosis: a single-cell RNA sequencing study . MULTIPLE SCLEROSIS JOURNAL . vol. 28 , 971 - 972 .

Waters S, Watson C, Jacobs BM, Foote IF, Dey S, Noyce AJ, Marshall CR ( 2021 ) . Speech‐in‐noise perception is a marker of preclinical Alzheimer’s disease . Alzheimer's &amp; Dementia vol. 17 , ( S5 ) Article e054639 ,

Storm CS, Kia DA, Almramhi MM, Bandres-Ciga S, Finan C, Noyce AJ, Kaiyrzhanov R, Middlehurst B et al. ( 2021 ) . Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome . Nature Communications vol. 12 , ( 1 ) Article 7342 ,

Foote I, Jacobs B, Watson C, Bothongo P, Waters S, Dobson R, Noyce A, Bhui K et al. ( 2021 ) . W26. A MULTIVARIATE GENOME-WIDE ASSOCIATION STUDY OF MODIFIABLE RISK FOR ALZHEIMER'S DISEASE: 269 LOCI ASSOCIATED WITH BRAIN HEALTH . European Neuropsychopharmacology vol. 51 , e159 - e159 .

Hone L, Jacobs BM, Marshall C, Giovannoni G, Noyce A, Dobson R ( 2021 ) . Age-specific effects of childhood Body Mass Index on multiple sclerosis risk .

Kuri A, Jacobs BM, Leddy S, Schmierer K, Turner B, Allen-Philbey K, Stennett A, Giovannoni G et al. ( 2021 ) . Evaluation of remote assessments for multiple sclerosis in an in-home setting . Multiple Sclerosis and Related Disorders vol. 54 , Article 103125 , 103125 - 103125 .

Jacobs BM, Noyce AJ, Bestwick J, Belete D, Giovannoni G, Dobson R ( 2021 ) . Gene-Environment Interactions in Multiple Sclerosis . Neurology Neuroimmunology &amp; Neuroinflammation vol. 8 , ( 4 ) Article e1007 ,

Blauwendraat C, Iwaki H, Makarious MB, Bandres‐Ciga S, Leonard HL, Grenn FP, Lake J, Krohn L et al. ( 2021 ) . Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease . Annals of Neurology vol. 90 , ( 1 ) 35 - 42 .

Chohan H, Senkevich K, Patel RK, Bestwick JP, Jacobs BM, Bandres Ciga S, Gan‐Or Z, Noyce AJ ( 2021 ) . Type 2 Diabetes as a Determinant of Parkinson's Disease Risk and Progression . Movement Disorders vol. 36 , ( 6 ) 1420 - 1429 .

Foote IF, Jacobs BM, Mathlin G, Watson CJ, Bothongo PLK, Waters S, Dobson R, Noyce AJ et al. ( 2021 ) . The Genetic Architecture of Alzheimer’s Disease Risk: A Genomic Structural Equation Modelling Study .

Jensen MP, Jacobs BM, Dobson R, Bandres‐Ciga S, Blauwendraat C, Schrag A, Noyce AJ ( 2021 ) . Lower Lymphocyte Count is Associated With Increased Risk of Parkinson's Disease . Annals of Neurology vol. 89 , ( 4 ) 803 - 812 .

Hone L, Jacobs B, Noyce A, Dobson R ( 2021 ) . Age-specific effects of childhood BMI on multiple sclerosis risk: a Mendelian Randomisation study . MULTIPLE SCLEROSIS JOURNAL . vol. 27 , 764 - 765 .

Auger SD, Jacobs BM, Dobson R, Marshall CR, Noyce AJ ( 2021 ) . Big data, machine learning and artificial intelligence: a neurologist's guide . PRACTICAL NEUROLOGY vol. 21 , ( 1 ) 4 - 11 .

Vickaryous N, Jitlal M, Jacobs BM, Middleton R, Chandran S, MacDougall NJJ, Giovannoni G, Dobson R ( 2020 ) . Remote testing of vitamin D levels across the UK MS population—A case control study . PLOS ONE vol. 15 , ( 12 ) e0241459 - e0241459 .

Jacobs BM, Smets I, Giovannoni G, Noyce A, Jokubaitis V, Dobson R ( 2020 ) . Regarding: Nicotinic acetylcholine receptors α7 and α9 modify tobacco smoke risk for multiple sclerosis . Multiple Sclerosis Journal vol. 27 , ( 8 ) 1311 - 1312 .

Foote IF, Jacobs BM, Noyce AJ, Korszun A, Bhui KS, Marshall CR ( 2020 ) . Exploring the shared genetic architecture of modifiable risk factors and related endophenotypes of Alzheimer’s disease: A genomic SEM study . Alzheimer's &amp; Dementia vol. 16 , ( S2 ) Article e045164 ,

Chohan H, Senkevich K, Patel RK, Bestwick JP, Jacobs BM, Ciga SB, Gan-Or Z, Noyce AJ ( 2020 ) . Type 2 diabetes as a determinant of Parkinson’s disease risk and progression .

Vickaryous N, Jitlal M, Jacobs BM, Middleton R, Chandran S, MacDougall NJJ, Giovannoni G, Dobson R ( 2020 ) . Remote testing of vitamin D levels across the UK MS population – a case control study .

Auger SD, Jacobs BM, Dobson R, Marshall CR, Noyce AJ ( 2020 ) . Big data, machine learning and artificial intelligence: a neurologist’s guide . Practical Neurology vol. 21 , ( 1 ) 4 - 11 .

Jacobs BM, Belete D, Bestwick J, Blauwendraat C, Bandres-Ciga S, Heilbron K, Dobson R, Nalls MA et al. ( 2020 ) . Parkinson’s disease determinants, prediction and gene–environment interactions in the UK Biobank . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 91 , ( 10 ) 1046 - 1054 .

Jensen MP, Jacobs BM, Dobson R, Bandres-Ciga S, Blauwendraat C, Schrag A, Noyce AJ ( 2020 ) . Low lymphocyte count is a risk factor for Parkinson’s disease .

Jacobs BM, Taylor T, Awad A, Baker D, Giovanonni G, Noyce AJ, Dobson R ( 2020 ) . Summary-data-based Mendelian randomization prioritizes potential druggable targets for multiple sclerosis . Brain Communications vol. 2 , ( 2 ) Article fcaa119 ,

Taylor TRP, Jacobs BM, Giovannoni G, Petrushkin H, Dobson R ( 2020 ) . Prevalence and demographics of multiple sclerosis-associated uveitis: a UK biobank study . Multiple Sclerosis and Related Disorders vol. 43 , Article 102209 , 102209 - 102209 .

Voormolen DC, Polinder S, von Steinbuechel N, Feng Y, Wilson L, Oppe M, Haagsma JA, Åkerlund C et al. ( 2020 ) . Health-related quality of life after traumatic brain injury: deriving value sets for the QOLIBRI-OS for Italy, The Netherlands and The United Kingdom . Quality of Life Research vol. 29 , ( 11 ) 3095 - 3107 .

Kuri A, Jacobs BM, Vickaryous N, Pakpoor J, Middeldorp J, Giovannoni G, Dobson R ( 2020 ) . Epidemiology of Epstein-Barr virus infection and infectious mononucleosis in the United Kingdom . BMC Public Health vol. 20 , ( 1 ) Article 912 ,

Leddy S, Jacobs B, Giovannoni G, Dobson R ( 2020 ) . Bone health, fracture risk, and Multiple Sclerosis: a UK Biobank study (3946) . Neurology vol. 94 , ( 15_supplement ) Article 3946 ,

Jacobs B, Giovannoni G, Dobson R ( 2020 ) . Environmental exposures associated with Multiple Sclerosis: a UK Biobank study (474) . Neurology vol. 94 , ( 15_supplement ) Article 474 ,

Belete D, Jacobs B, Schrag A, Noyce A ( 2020 ) . Exploring the Parkinson’s disease phenome in the UK Biobank population (4040) . Neurology vol. 94 , ( 15_supplement ) Article 4040 ,

Jacobs BM, Giovannoni G, Cuzick J, Dobson R ( 2020 ) . Systematic review and meta-analysis of the association between Epstein–Barr virus, multiple sclerosis and other risk factors . Multiple Sclerosis Journal vol. 26 , ( 11 ) 1281 - 1297 .

Jacobs BM, Noyce A, Bestwick J, Belete D, Giovannoni G, Dobson R ( 2020 ) . Gene-environment interactions in Multiple Sclerosis: a UK Biobank study .

Jacobs BM, Noyce AJ, Giovannoni G, Dobson R ( 2020 ) . BMI and low vitamin D are causal factors for multiple sclerosis . Neurology Neuroimmunology &amp; Neuroinflammation vol. 7 , ( 2 ) Article e662 ,

Jacobs BM, Noyce AJ, Hardy CJD, Warren JD, Marshall CR ( 2020 ) . Estimating the causal effect of hearing loss on Alzheimer’s disease: a Mendelian randomisation study .

Jacobs BM, Belete D, Bestwick JP, Blauwendraat C, Bandres-Ciga S, Heilbron K, Dobson R, Nalls MA et al. ( 2020 ) . Parkinson’s disease determinants, prediction and gene-environment interactions in the UK Biobank .

Kuri A, Jacobs BM, Vickaryous N, Pakpoor J, Middeldorp J, Giovannoni G, Dobson R ( 2020 ) . Epidemiology of Epstein-Barr Virus infection and Infectious Mononucleosis in the United Kingdom .

Jacobs BM, Taylor T, Awad A, Baker D, Giovanonni G, Noyce A, Dobson R ( 2020 ) . Summary-data-based mendelian randomisation reveals druggable targets for multiple sclerosis .

Leddy S, Jacobs B, Giovannoni G, Dobson R ( 2020 ) . Bone health, fracture risk, and Multiple Sclerosis: a UK Biobank study . NEUROLOGY . vol. 94 ,

Jacobs B, Giovannoni G, Dobson R ( 2020 ) . Environmental exposures associated with Multiple Sclerosis: a UK Biobank study . NEUROLOGY . vol. 94 ,

Belete D, Jacobs B, Schrag A, Noyce A ( 2020 ) . Exploring the Parkinson's disease phenome in the UK Biobank population . NEUROLOGY . vol. 94 ,

Jacobs B, Noyce A, Bestwick J, Belete D, Giovannoni G, Dobson R ( 2020 ) . Gene-environment interactions in multiple sclerosis: a uk biobank study . MULTIPLE SCLEROSIS JOURNAL . vol. 26 , 367 - 367 .

Belete D, Jacobs B, Bestwick J, Blauwendraat C, Bandres-Ciga S, Heilbron K, Dobson R, Nalls M et al. ( 2020 ) . Parkinson's disease determinants, prediction and gene-environment interactions in the UK Biobank . MOVEMENT DISORDERS . vol. 35 , S74 - S74 .

Jacobs BM, Sarathchandra N, Karela M, Daniels LE, Purkayastha N ( 2020 ) . STREAMLINING PRIMARY CARE REFERRALS TO AN EARLY INFLAMMATORY ARTHRITIS (EIA) CLINIC: DISTINGUISHING BETWEEN PATIENTS WITH OSTEOARTHRITIS AND INFLAMMATORY ARTHRITIS . RHEUMATOLOGY . vol. 59 ,

Leddy S, Jacobs BM, Giovannoni G, Dobson R ( 2020 ) . To examine the impact of Multiple Sclerosis on bone health and explore mechanisms for this association . EUROPEAN JOURNAL OF NEUROLOGY . vol. 27 , 981 - 981 .

Vickaryous N, Garjani A, Jacobs B, Jitlal M, Middleton R, Das Nair R, Tuite-Dalton K, Hunter R et al. ( 2020 ) . Vitamin D levels in the UK MS population and COVID-19 susceptibility . MULTIPLE SCLEROSIS JOURNAL . vol. 26 , 55 - 55 .

Baker D, Jacobs BM, Gnanapavan S, Schmierer K, Giovannoni G ( 2019 ) . Plasma cell and B cell-targeted treatments for use in advanced multiple sclerosis . Multiple Sclerosis and Related Disorders vol. 35 , 19 - 25 .

Jacobs BM, Giovannoni G, Cuzick J, Dobson R ( 2019 ) . Systematic review and meta-analysis of the association between Epstein-Barr virus, Multiple Sclerosis, and other risk factors .

Bell JS, Spencer JI, Yates RL, Yee SA, Jacobs BM, DeLuca GC ( 2018 ) . Invited Review: From nose to gut – the role of the microbiome in neurological disease . Neuropathology and Applied Neurobiology vol. 45 , ( 3 ) 195 - 215 .

Jacobs B ( 2018 ) . Pneumatosis Intestinalis and Intestinal Perforation in a Patient Receiving Tocilizumab . Archives of Rheumatology vol. 33 , ( 3 ) 372 - 375 .

Jacobs BM, Ammoscato F, Giovannoni G, Baker D, Schmierer K ( 2018 ) . Cladribine: mechanisms and mysteries in multiple sclerosis . Journal of Neurology, Neurosurgery &amp; Psychiatry vol. 89 , ( 12 ) 1266 - 1271 .

Jacobs BM, Giovannoni G, Schmierer K ( 2018 ) . No Evident Disease Activity—More Than a Risky Ambition? . JAMA Neurology vol. 75 , ( 7 ) 781 - 781 .

Ceronie B, Dubuisson N, Jacobs BM, Mao Z, Ammoscato F, Lock H, Longhurst H, Giovannoni G et al. ( 2018 ) . Cladribine for the Effective Control of Multiple Sclerosis via Memory B Cell Depletion (S52.007) . Neurology . vol. 90 ,

Ceronie B, Jacobs BM, Baker D, Dubuisson N, Mao Z, Ammoscato F, Lock H, Longhurst HJ et al. ( 2018 ) . Cladribine treatment of multiple sclerosis is associated with depletion of memory B cells . Journal of Neurology vol. 265 , ( 5 ) 1199 - 1209 .

Jacobs B, Ammoscato F, Ceronie B, Xenakis T, Baker D, Giovannoni G, Schmierer K ( 2018 ) . Explaining long-term depletion of memory B lymphocytes after cladribine treatment . MULTIPLE SCLEROSIS JOURNAL . vol. 24 , 894 - 894 .

Yates RL, Esiri MM, Palace J, Jacobs B, Perera R, DeLuca GC ( 2017 ) . Fibrin(ogen) and neurodegeneration in the progressive multiple sclerosis cortex . Annals of Neurology vol. 82 , ( 2 ) 259 - 270 .

Jacobs BM ( 2015 ) . A dangerous method? The use of induced pluripotent stem cells as a model for schizophrenia . Schizophrenia Research vol. 168 , ( 1-2 ) 563 - 568 .

Wei W-C, Jacobs B, Becker EBE, Glitsch MD ( 2015 ) . Reciprocal regulation of two G protein-coupled receptors sensing extracellular concentrations of Ca\n ²⁺\n and H\n ⁺ . Proceedings of the National Academy of Sciences vol. 112 , ( 34 ) 10738 - 10743 .

Jacobs BM ( 2014 ) . Is there a moral obligation to select healthy children? . Journal of Medical Ethics vol. 41 , ( 8 ) 696 - 700 .

Jacobs BM ( 2014 ) . Stemming the Hype: What Can We Learn from iPSC Models of Parkinson's Disease and How Can We Learn It? . Journal of Parkinson’s Disease vol. 4 , ( 1 ) 15 - 27 .

Jacobs B ( 2012 ) . The case of M . BMJe236 - e236 .

Jacobs B . Genetic and environmental determinants of Multiple Sclerosis risk and severity in diverse ancestral backgrounds .

Jacobs BM, Tank P, Bestwick JP, Noyce A, Marshall C, Giovannoni G, Dobson R . Modifiable Risk Factors for Multiple Sclerosis are Consistent Across Diverse Ethnic Backgrounds: A Nested Case-Control Study in a UK Population-Based Cohort .