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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: MRS Hannah Nicholls

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Young M, Nicholls H, Dambure S, Ramchunder Z, Mody EN, Cullen F, Henson SM, Aung N et al. ( 2026 ) . 559 NLRP3 signalling links diabetic metabolic stress to cardiac metabolic remodelling . Conference: Basic Sciencea294.1 - a2a294 .
Nicholls HL, Vargas JD, Sanghvi MM, Ahn H-S, Chahal CAA, Khanji MY, Petersen SE, Munroe PB et al. ( 2026 ) . Genome-wide analysis of cardiac ventricular phenotypes reveals novel loci and therapeutic targets for heart failure . Nature Communications vol. 17 , ( 1 )
Aslett LJM, Aslett LJM, Avramescu A, Bakewell N, Birds I, Bowler L, Camilleri MPJ, Chung S-C et al. ( 2025 ) . DECOVID: A UK Two-Center Harmonized Database of Acute Care Electronic Health Records for COVID-19 Research . Data vol. 10 , ( 12 )
Shyam-Sundar V, Nicholls H, Slabaugh G, Mohiddin SA, Petersen SE, Aung N ( 2025 ) . Cardiometabolic polygenic risk profiling improves prediction of incident major adverse cardiovascular events . European Heart Journal . vol. 46 ,
Apti E, Nicholls H, Jacobsen J, Smedley D, Aung N ( 2025 ) . Genetic and drug repurposing insights into hypertrophic cardiomyopathy: a machine learning approach . European Heart Journal vol. 46 , ( Supplement_1 )
Rasooly D, Peloso G, Giambartolomei C, Nicholls H, Liu C, Aung N, Gravel-Pucillo K, Ferolito B et al. ( 2025 ) . Abstract 4362686: Large-scale genome-wide association meta-analysis and proteome- and transcriptome-wide Mendelian randomization reveal novel therapeutic targets for heart failure . Circulation vol. 152 , ( Suppl_3 ) a4362686 - a4362686 .
Sanghvi M, Nicholls HL, Petersen SE, Munroe P, Aung N ( 2025 ) . A NOVEL SARCOPENIC OBESITY PHENOTYPE DERIVED FROM CARDIAC IMAGING PREDICTS CARDIOVASCULAR OUTCOMES AND GENOME-WIDE ANALYSIS HIGHLIGHTS CARDIAC GENES . Journal of the American College of Cardiology . vol. 85 ,
Aung N, Nicholls HL, Chahal CAA, Khanji MY, Rauseo E, Chadalavada S, Petersen SE, Munroe PB et al. ( 2024 ) . Prevalence, Cardiac Phenotype, and Outcomes of Transthyretin Variants in the UK Biobank Population . JAMA Cardiology vol. 9 , ( 11 ) 964 - 972 .
Shyam-Sundar V, Nicholls H, Chadalavada S, Vargas J, Slabaugh G, Mohiddin S, Petersen S, Aung N ( 2024 ) . The impact of multimorbidity on cardiac remodelling in the UK Biobank . European Heart Journal . vol. 45 ,
Nicholls HL, Vargas J, Chahal A, Khanji M, Petersen S, Munroe P, Aung N ( 2024 ) . Common and rare variant association study of left and right ventricular phenotypes identifies novel genetic loci and therapeutic targets for heart failure . Conference: European Society of Human Genetics ( Berlin, Germany ) from: 01/06/2024 to: 04/06/2024 ,
Shyam-Sundar V, Nicholls H, Harding D, Slabaugh G, Mohiddin S, Petersen S, Aung N ( 2024 ) . 14 A single centre retrospective study of patients presenting with acute forms of myocarditis: insights from clinical and cardiac MRI data . Conference: ACHD/Valve disease/Pericardial disease/Cardiomyopathya17 - a18 .
Nicholls H, Vargas J, Chahal A, Khanji M, Petersen S, Munroe P, Aung N ( 2024 ) . Common and rare variant association study of left and right ventricular phenotypes identifies novel genetic loci and therapeutic targets for heart failure . Conference: Londomics Symposium from: 20/05/2024 to: 20/05/2024 ,
Olczak KJ, Taylor‐Bateman V, Nicholls HL, Traylor M, Cabrera CP, Munroe PB ( 2021 ) . Hypertension genetics past, present and future applications . Journal of Internal Medicine vol. 290 , ( 6 ) 1130 - 1152 .
Nicholls HL, John CR, Watson DS, Munroe PB, Barnes MR, Cabrera CP ( 2020 ) . Reaching the End-Game for GWAS: Machine Learning Approaches for the Prioritization of Complex Disease Loci . Frontiers in Genetics vol. 11 ,
Cabrera CP, Ng FL, Nicholls HL, Gupta A, Barnes MR, Munroe PB, Caulfield MJ ( 2019 ) . Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicated . Human Molecular Genetics vol. 28 , ( R2 ) r151 - r161 .
Lopes LR, Aung N, van Duijvenboden S, Nicholls HL, Burns R, Jager J, Lorenzini M, Akhtar MM et al. . Hypertrophic cardiomyopathy: a genome wide association meta-analysis and polygenic risk score .
Sanghvi M, Nicholls H, Kaplan T, Petersen S, Timmons J, Munroe P, Aung N . Imaging-Derived Sarcopenic Obesity and Cardiovascular Outcomes: Insights Into Heart Failure Risk and Muscle Biology . Journal of the American College of Cardiology
Nicholls H, Ng FL, Watson D, Jacobsen J, Warren H, Cacheiro P, Smedley D, Munroe P et al. . Post-GWAS machine learning prioritizes key genes regulating blood pressure .
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