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Research

Publications: MR Sammy El-Mansi

Mobayen G, El-Mansi S, Chion A, Nightingale TD, McKinnon TAJ ( 2025 ) . Probing rare von Willebrand disease–causing mutations in the D4 and C-domains of von Willebrand factor . Research and Practice in Thrombosis and Haemostasis vol. 9 , ( 4 )
El-Mansi S, Mitchell TP, Mobayen G, McKinnon TAJ, Miklavc P, Frick M, Nightingale TD ( 2024 ) . Myosin-1C augments endothelial secretion of von Willebrand factor by linking contractile actomyosin machinery to the plasma membrane . Blood Advances vol. 8 , ( 17 ) 4714 - 4726 .
El-Mansi S, Robinson CL, Kostelnik KB, McCormack JJ, Mitchell TP, Lobato-Márquez D, Rajeeve V, Cutillas PR et al. ( 2022 ) . Proximity proteomics identifies septin and PAK2 as decisive regulators of actomyosin expulsion of von Willebrand factor . Blood vol. 141 , ( 8 ) 930 - 944 .
El-Mansi S, Nightingale TD ( 2020 ) . Emerging mechanisms to modulate VWF release from endothelial cells . The International Journal of Biochemistry & Cell Biology vol. 131 ,
El-Mansi S, Irwin A, McKinney C, Bradshaw A ( 2018 ) . 7 Assessing adenoviral delivery of angiotensin-(1–9) to prevent human vascular smooth muscle cell proliferation and migration in vitro and neointima formation in vivo . Heart . Conference: Oral Presentations vol. 104 ,
El-mansi S, Bradshaw AC ( 2017 ) . Assessing adenoviral-mediated delivery of Angiotensin-(1-9) to prevent human vascular smooth muscle cell migration . HUMAN GENE THERAPY . vol. 28 , A34 - A34 .
El-Mansi S, Deegan KM, Donker L, Godinho S, Nightingale TD . Endothelial β-PIX (ARHGEF7) drives exocytosis through enabling the dynamic reorganisation of the cytoskeleton .
El-Mansi S, Al-Saegh M, Rolas L, Golding M, Voisin M-B, Nourshargh S, Nightingale TD . Force sensing by Piezo1 regulates endothelial secretory granule exocytosis .
El-Mansi S, Mitchell TP, Miklavc P, Frick M, Nightingale TD . The unconventional Myosin-1C augments endothelial secretion of von Willebrand factor by linking contractile actomyosin machinery to the plasma membrane .