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Research

Publications: CDR Paul Rees

Moll K, Sharpe Z, Harding L, Gomez C, Duckett Z, Greer N, Tiba M, Gherasim C et al. ( 2025 ) . Abstract Sat203: Rapid UCH-L1 and GFAP Brain Injury Biomarker Detection in Out-of-Hospital Cardiac Arrest: A Swine Model and Prehospital Feasibility Study . Circulation vol. 152 , ( Suppl_3 ) asat203 - asat203 .
Burns B, Kruit N, Dennis M, Shinar Z, Rees P, Wong S, Plunkett B, Reid C et al. ( 2025 ) . Common femoral artery access in emergency medicine . Emergency Medicine Journal
Khan Z, Tyrovolas K, Rees P ( 2025 ) . Usefulness of a Left Ventriculogram in Patients Presenting With Acute Coronary Syndrome Due to Takotsubo Cardiomyopathy: A Case Series . Cureus vol. 17 , ( 9 )
Russo RM, Schmitt J, Gage CP, Barratt J, Beckett A, Rees P, Del Valle FS, Aries P et al. ( 2025 ) . Scoping review and recommendation to establish standardized best practices for resuscitative endovascular balloon occlusion of the aorta in combat casualties: A North Atlantic Treaty Organization exploratory team report . Journal of Trauma and Acute Care Surgery vol. 99 , ( 3S ) s164 - s169 .
Cowley A, Cody D, Rees P ( 2025 ) . Does critical care paramedic deployment improve delivery of post-resuscitation care following out-of-hospital cardiac arrest? A retrospective cohort study . British Paramedic Journal vol. 10 , ( 1 ) 1 - 9 .
Khan Z, Eldabe F, Tyrovolas K, Rathod K, Rees P ( 2025 ) . Post-Anaphylaxis Adrenaline-Induced Takotsubo Cardiomyopathy: A Case Report . Cureus vol. 17 , ( 5 )
Sin ELPW-P, Hibberd O, Price J, Lachowycz K, Major R, Rees P, Barnard E ( 2025 ) . Short and long-term complications of prehospital arterial catheterisation performed by a Helicopter Emergency Medical Service in the United Kingdom . Critical Care vol. 29 , ( 1 )
Aziz S, Barratt J, Lachowycz K, Major R, Barnard EBG ( 2024 ) . The association between intra-arrest arterial blood pressure and return of spontaneous circulation in out-of-hospital cardiac arrest . Resuscitation vol. 205 ,
Price J, Rees P, Lachowycz K, Starr Z, Pareek N, Keeble TR, Major R, Barnard EBG ( 2024 ) . Increased survival for resuscitated Utstein-comparator group patients conveyed directly to cardiac arrest centres in a large rural and suburban population in England . Resuscitation vol. 201 ,
Aziz S, Barratt J, Wilson-Baig N, Lachowycz K, Major R, Barnard EBG, Rees P ( 2024 ) . A protocol for the ERICA-ARREST feasibility study of Emergency Resuscitative Endovascular Balloon occlusion of the Aorta in Out-of-Hospital Cardiac Arrest . Resuscitation Plus vol. 19 ,
Aziz S, Clough M, Butterfield E, Starr Z, Lachowycz K, Price J, Barnard EBG, Rees P ( 2024 ) . The association between prehospital post–return of spontaneous circulation core temperature and survival after out-of-hospital cardiac arrest . European Journal of Emergency Medicine vol. 31 , ( 5 ) 356 - 362 .
Price J, Dowsing J, Barratt J, Lachowycz K, Rees P, Major R, Aziz S, Barnard EBG ( 2024 ) . Air Transport Medicine: From the Field . Air Medical Journal vol. 43 , ( 3 ) 198 - 200 .
Aziz S, Lachowycz K, Major R, Rees P, Barratt J ( 2024 ) . Implementation of advanced vascular access, physiological monitoring and goal-directed resuscitation during OHCA in a helicopter emergency medical service . The Journal of Vascular Access vol. 26 , ( 3 ) 982 - 988 .
Butterfield ED, Price J, Bonsano M, Lachowycz K, Starr Z, Edmunds C, Barratt J, Major R et al. ( 2024 ) . Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK helicopter emergency medical service– a retrospective observational review of practice . Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine vol. 32 , ( 1 )
Khan Z, Batchelor T, Rees P ( 2024 ) . Bronchogenic cyst: a rare cause of palpitations and atrial fibrillation . BMJ Case Reports vol. 17 , ( 3 )
Marsden M, Barratt J, Donald-Simpson H, Wilkinson T ( 2023 ) . Selective aortic arch perfusion: a first-in-human observational cadaveric study . Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine vol. 31 , ( 1 )
Jones DA, Beirne A-M, Kelham M, Rathod KS, Andiapen M, Wynne L, Godec T, Forooghi N et al. ( 2023 ) . Computed Tomography Cardiac Angiography Before Invasive Coronary Angiography in Patients With Previous Bypass Surgery: The BYPASS-CTCA Trial . Circulation vol. 148 , ( 18 ) 1371 - 1380 .
Price J, Rudman J, Schoenfeld D, Thomas SA, Rees P, Bloom B, McCartin M, Blumen I et al. ( 2023 ) . Survivorship With Incrementally Faster Times to Primary Percutaneous Coronary Intervention (SWIFT-PPCI): A Systematic Review and Meta-Analysis . The American Journal of Cardiology vol. 207 , 356 - 362 .
Sullivan A, Dennis ASC, Rathod K, Jones D, Rosmini S, Manisty C, Bhattacharyya S, Foggo V et al. ( 2023 ) . Pericardial Fluid Analysis in Diagnosis and Prognosis of Patients Who Underwent Pericardiocentesis . The American Journal of Cardiology vol. 198 , 79 - 87 .
Edwards T, Rees P ( 2022 ) . Out-of-hospital cardiac arrest complicated by hyperthermia . Resuscitation Plus vol. 12 ,
Mion M, Simpson R, Johnson T, Oriolo V, Gudde E, Rees P, Quinn T, Vopelius-Feldt VJ et al. ( 2022 ) . British Cardiovascular Intervention Society Consensus Position Statement on Out-of-hospital Cardiac Arrest 2: Post-discharge Rehabilitation . Interventional Cardiology Reviews Research Resources vol. 17 ,
Pareek N, Rees P, Quinn T, Von Vopelius-Feldt J, Gallagher S, Mozid A, Johnson T, Simpson R et al. ( 2022 ) . British Cardiovascular Interventional Society Consensus Position Statement on Out-of-Hospital Cardiac Arrest 1: Pathway of Care . Interventional Cardiology Reviews Research Resources vol. 17 ,
Bajaj R, Ramasamy A, Brown JT, Koganti S, Little C, Rathod KS, Jones DA, Rees P et al. ( 2022 ) . Treatment Strategies and Outcomes of Emergency Left Main Percutaneous Coronary Intervention . The American Journal of Cardiology vol. 177 , 1 - 6 .
Edwards T, Rees P ( 2022 ) . Out-of-Hospital Cardiac Arrest Complicated by Hyperthermia .
Jones TN, Kelham M, Rathod KS, Knight CJ, Proudfoot A, Jain AK, Wragg A, Ozkor M et al. ( 2021 ) . Validation of the CREST score for predicting circulatory-aetiology death in out-of-hospital cardiac arrest without STEMI . Am J Cardiovasc Dis vol. 11 , ( 6 ) 723 - 733 .
Frain K, Rathod KS, Tumi E, Chen Y, Hamshere S, Choudry F, Akhtar MM, Curtis M et al. ( 2021 ) . The impact of the COVID-19 pandemic on the delivery of primary percutaneous coronary intervention in STEMI . Am J Cardiovasc Dis vol. 11 , ( 5 ) 647 - 658 .
Marsden MER, Park C, Barratt J, Tai N ( 2021 ) . Defence Medical Services’ REBOA training course . BMJ Military Health vol. 169 , ( 5 )
Frain K ( 2021 ) . Intra-aortic balloon pump versus percutaneous Impella© in emergency revascularisation for myocardial infarction and cardiogenic shock: systematic review . Perfusion vol. 39 , ( 1 ) 45 - 59 .
Marsden MER, Buckley AM, Tai N ( 2021 ) . Balloons on the battlefield: REBOA implementation in the UK Defence Medical Services . BMJ Military Health vol. 169 , ( 5 ) 448 - 451 .
Kelham M, Jones TN, Rathod KS, Guttmann O, Proudfoot A, Rees P, Knight CJ, Ozkor M et al. ( 2020 ) . An observational study assessing the impact of a cardiac arrest centre on patient outcomes after out-of-hospital cardiac arrest (OHCA) . European Heart Journal Acute Cardiovascular Care vol. 9 , ( 4_suppl ) s67 - s73 .
Frain K ( 2020 ) . 43 The role of mechanically-supported emergency percutaneous coronary intervention in cardiogenic shock . Conference: Acute Coronary Syndromes & Interventional Cardiologya36.1 - a3a36 .
Slim N, West CT, Rees P, Gaunt M ( 2020 ) . The REBOA window: a cadaveric study delineating the optimum site for austere cannulation of the femoral artery for resuscitative endovascular balloon occlusion of the aorta . BMJ Military Health vol. 167 , ( 6 ) 383 - 386 .
Hamshere S, Byrne A, Guttmann O, Rees P, Bourantas C, Weerakody R, Wragg A, Knight C et al. ( 2018 ) . An observational study of clinical outcomes of everolimus-eluting bioresorbable scaffolds comparing the procedural use of optical coherence tomography against angiography alone . Coronary Artery Disease vol. 29 , ( 6 ) 482 - 488 .
Rees P ( 2018 ) . Response to: ‘REBOA at Role 2 Afloat: resuscitative endovascular balloon occlusion of the aorta as a bridge to damage control surgery in the military maritime setting’ by Rees et al . BMJ Military Health vol. 165 , ( 3 ) 213 - 214 .
Kalogeropoulos AS, Kennon S, Karamasis GV, Smith EJ, Rees P ( 2018 ) . Successful Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction During Resuscitation From Cardiac Arrest by Combined Mechanical Chest Compressions and Intra-aortic Balloon Pump Counterpulsation . A&A Practice vol. 10 , ( 12 ) 323 - 326 .
Woolley T, Thompson P, Kirkman E, Reed R, Ausset S, Beckett A, Bjerkvig C, Cap AP et al. ( 2018 ) . Trauma Hemostasis and Oxygenation Research Network position paper on the role of hypotensive resuscitation as part of remote damage control resuscitation . Journal of Trauma and Acute Care Surgery vol. 84 , ( 6S ) s3 - s13 .
Parsons IT, Cox AT ( 2018 ) . Military application of mechanical CPR devices: a pressing requirement? . BMJ Military Health vol. 164 , ( 6 ) 438 - 441 .
Rees PSC, Watts SA, Kirkman E ( 2018 ) . Intravascular ultrasound, performed during resuscitative endovascular balloon occlusion of the aorta (REBOA), confirms correct balloon deployment and haemostasis - a potential solution for remote, austere and military settings . Journal of the Royal Naval Medical Service vol. 104 , ( 1 ) 12 - 17 .
Rees P, Waller B, Buckley AM, Doran C, Bland S, Matthews J ( 2017 ) . REBOA at Role 2 Afloat: resuscitative endovascular balloon occlusion of the aorta as a bridge to damage control surgery in the military maritime setting . BMJ Military Health vol. 164 , ( 2 )
Dickson SJ, Clay KA, Adam M, Ardley C, Bailey MS, Burns DS, Cox AT, Craig DG et al. ( 2017 ) . Enhanced case management can be delivered for patients with EVD in Africa: Experience from a UK military Ebola treatment centre in Sierra Leone . Journal of Infection vol. 76 , ( 4 ) 383 - 392 .
Buckley AM, Cox AT ( 2017 ) . Shocking the system: AEDs in military resuscitation . BMJ Military Health vol. 164 , ( 4 )
Rees PSC ( 2017 ) . Novel Combination of Mechanical Cardiopulmonary Resuscitation and Intra-Aortic Balloon Counterpulsation in Refractory Cardiac Arrest in the Cardiac Catheterization Laboratory . EUROPEAN JOURNAL OF HEART FAILURE . vol. 19 , 17 - 17 .
Rees PSC ( 2016 ) . Pre-hospital Management of the Critically Injured Patient . Trauma and Combat Critical Care in Clinical Practice , Springer Nature
Proffitt A, Rees P ( 2016 ) . The athletic ECG . Journal of the Royal Naval Medical Service vol. 102 , ( 1 ) 50 - 55 .
Hutchings S, Cantillon L, Keating-Brown P, Jeffreys S, Muzvidziwa C, Rees P ( 2015 ) . Nurse-delivered focused echocardiography to determine intravascular volume status in a deployed maritime critical care unit . Journal of the Royal Naval Medical Service vol. 101 , ( 2 ) 124 - 128 .
Rees PSC, Babu GG, Boston-Griffiths EA, Bognolo G, Hayward M, Kolvekar S, Yap J ( 2010 ) . 014 Atorvastatin protects human myocardium from lethal ischaemia-reperfusion injury by activating the risk pathway . Heart . Conference: BCS Abstracts 2010 vol. 96 , a11 - a11 .
Barker S, White S, Bailey K ( 2015 ) . Acute chest pain in contingency operations at a Role 1 facility . BMJ Military Health vol. 161 , ( 3 )
Parsons I, White S, Gray HH, Rees P ( 2015 ) . Coronary artery disease in the military patient . BMJ Military Health vol. 161 , ( 3 )
Schibler M, Vetter P, Cherpillod P, Petty TJ, Cordey S, Vieille G, Yerly S, Siegrist C-A et al. ( 2015 ) . Clinical features and viral kinetics in a rapidly cured patient with Ebola virus disease: a case report . The Lancet Infectious Diseases vol. 15 , ( 9 ) 1034 - 1040 .
Rees P, Ardley C, Lamb L, Fletcher T, Dickson S, Nicholson-Roberts T ( 2015 ) . 132 Targeted Resuscitation Using Echocardiography in a Military Ebola Virus Disease Treatment Unit . Heart vol. 101 , ( Suppl 4 )
Rees P ( 2015 ) . Safety and feasibility of a strategy of early central venous catheter insertion in a deployed UK military Ebola virus disease treatment unit: response to comments by Bordes et al . Intensive Care Medicine vol. 41 , ( 6 ) 1169 - 1169 .
Nicholson-Roberts T, Fletcher T, Rees P, Dickson S, Hinsley D, Lamb L ( 2015 ) . Ebola virus disease managed with blood product replacement and point of care tests in Sierra Leone . QJM vol. 108 , ( 7 ) 571 - 572 .
Lamb L, Robson J, Ardley C, Bailey M, Dickson S, Fletcher T, Hutley E ( 2015 ) . Bacterial co-infection is rare in patients with Ebola virus disease in a military Ebola virus disease treatment unit in Sierra Leone . Journal of Infection vol. 71 , ( 3 ) 406 - 407 .
Rees PSC, Lamb LEM, Nicholson-Roberts TC, Ardley CN, Hinsley DE ( 2015 ) . Safety and feasibility of a strategy of early central venous catheter insertion in a deployed UK military Ebola virus disease treatment unit . Intensive Care Medicine vol. 41 , ( 5 ) 735 - 743 .
Pavlidis AN, Karamasis GV ( 2015 ) . Balloon-assisted tracking during primary percutaneous coronary intervention . Acute Cardiac Care vol. 17 , ( 1 ) 26 - 28 .
Rees P, Ardley C, Lamb L, Fletcher T, Bailey M, Nicholson-Roberts T, Hinsley D ( 2015 ) . TARGETED RESUSCITATION USING ECHOCARDIOGRAPHY IN A MILITARY EBOLA VIRUS DISEASE TREATMENT UNIT . HEART . vol. 101 , A76 - A76 .
Rees PSC, Ardley C, Bailey M, Dickson S, Fletcher T, Lamb L ( 2014 ) . Op GRITROCK: the Royal Navy supports defence efforts to tackle Ebola . Journal of the Royal Naval Medical Service vol. 100 , ( 3 ) 228 - 230 .
Hutchings SD, Howarth G, Rees P ( 2013 ) . Conducting clinical research in the deployed intensive care unit: challenges and solutions . Journal of the Royal Naval Medical Service vol. 99 , ( 3 ) 151 - 153 .
Akhtar MM, Hunter-Dunn C, Weaver A, Rees P ( 2013 ) . Abstract 18123: An Integrated Resuscitation Service, Combining a Specialist Pre-Hospital Physician Response Unit With Delivery to a Dedicated High-Volume Cardiac Arrest Centre, Optimises Survival Following Cardiac Arrest . Circulation vol. 128 , ( suppl_22 )
Hunter-Dunn C, Rees P ( 2013 ) . An integrated resuscitation service, combining a specialist prehospital physician response unit with delivery to a dedicated high-volume cardiac arrest centre, optimises survival following cardiac arrest . Resuscitation . vol. 84 , s80 - s81 .
Rees PSC, Hutchings SD ( 2013 ) . 117 ECHOCARDIOGRAPHY, PERFORMED DURING DAMAGE CONTROL RESUSCITATION, CAN BE USED TO MONITOR THE HAEMODYNAMIC RESPONSE TO VOLUME INFUSION IN THE DEPLOYED MILITARY CRITICAL CARE UNIT . Heart . vol. 99 ,
Hutchings SD ( 2013 ) . Trauma Resuscitation Using Echocardiography in a Deployed Military Intensive Care Unit . Journal of the Intensive Care Society vol. 14 , ( 2 ) 120 - 125 .
Rees PSC, Davidson SM, Harding SE, McGregor C, Yellon DM ( 2013 ) . The Mitochondrial Permeability Transition Pore as a Target for Cardioprotection in Hypertrophic Cardiomyopathy . Cardiovascular Drugs and Therapy vol. 27 , ( 3 ) 235 - 237 .
Rees PSC, Fernandez J, Swallow R, Talwar S ( 2012 ) . Safety and efficacy of percutaneous coronary intervention for unprotected left main stem disease in a high volume non-surgical centre . CIRCULATION . vol. 125 , E670 - E670 .
Rees PSC ( 2012 ) . TRAUMA RESUSCITATION USING ECHOCARDIOGRAPHY IN A DEPLOYED MILITARY INTENSIVE CARE UNIT . INTENSIVE CARE MEDICINE . vol. 38 , S23 - S24 .
Ludman AJ, Hausenloy DJ, Babu G, Hasleton J, Venugopal V, Boston-Griffiths E, Yap J, Lawrence D ( 2011 ) . Failure to recapture cardioprotection with high-dose atorvastatin in coronary artery bypass surgery: a randomised controlled trial . Basic Research in Cardiology vol. 106 , ( 6 ) 1387 - 1395 .
Rees PSC, Hausenloy DJ, Yellon DM ( 2011 ) . Atorvastatin, Administered at the Onset of Reperfusion, Protects Human Myocardium Against Lethal Reperfusion Injury by Activation of the RISK pathway . JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY . vol. 58 , B119 - B119 .
Rees PSC, Davidson SM, Harding SE, Elliott PM, Hausenloy DJ ( 2011 ) . The Mitochondrial Permeability Transition Pore is a Target for Pharmacological Cardioprotection in Human Hypertrophic Cardiomyopathy . JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY . vol. 58 , B119 - B119 .
Rees PSC, Davidson SM, Elliot PM, Yellon DM ( 2010 ) . BAS/BSCR45 The mitochondrial permeability transition pore as a target for cardioprotection in ventricular cardiomyocytes harvested from patients with obstructive hypertrophic cardiomyopathy . Heart vol. 96 , ( 17 )
Rees PSC, Davidson SM, Harding SE, Elliott PM, Hausenloy DJ ( 2010 ) . The mitochondrial permeability transition pore is a functional target for cardioprotection in human hypertrophic cardiomyopathy . EUROPEAN HEART JOURNAL . vol. 31 , 925 - 925 .
Rees PSC, Ludman AJ, Teoh KL, Bognolo G, Kolvekar S, Yap J, Lawrence D, Hayward M ( 2009 ) . HIGH-DOSE ORAL ATORVASTATIN PRETREATMENT OF PATIENTS UNDERGOING CARDIAC SURGERY PROTECTS ATRIAL MUSCLE AGAINST SIMULATED ISCHAEMIA-REPERFUSION INJURY . HEART . vol. 95 , A12 - A12 .
Lyon AR, Rees PS, Prasad S ( 2008 ) . Authors' response to “Stress (Takotsubo) cardiomyopathy—a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning” . Nature Reviews Cardiology vol. 5 , ( 6 ) e2 - e2 .
Lyon AR, Rees PS, Prasad S, Poole-Wilson PA, Harding SE ( 2008 ) . Stress (Takotsubo) cardiomyopathy—a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning . Nature Clinical Practice Cardiovascular Medicine vol. 5 , ( 1 ) 22 - 29 .
Kehoe A ( 2006 ) . Developments in pre-hospital care: is the specialty coming of age? . Journal of the Royal Naval Medical Service vol. 92 , ( 3 ) 140 - 142 .
Butterfield ED, Bonsano M, Price J, Lachowycz K, Starr Z, Edmunds C, Barratt J, Major R et al. . Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK Helicopter Emergency Medical Service – a retrospective observational review of practice .
Marsden MER, Barratt J, Donald-Simpson H, Wilkinson T, Manning J, Rees P . Selective Aortic Arch Perfusion: A First-in-Man Report of a Novel Endovascular Resuscitation Modality .