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Research

Publications: DR Cristina Simonet

Torricelli R, Kenny JE, Bache E, Pérez-Carbonell L, Huxford BF, Chohan H, Leschziner G, Alty J et al. ( 2026 ) . Handwriting patterns in isolated rapid eye movement sleep behaviour disorder . Journal of Parkinson’s Disease
Smith LJ, Jeyaganesh J, Li X, Gill A, Schrag A, Huxford B, Simonet C, Pérez-Carbonell L et al. ( 2026 ) . The Use of a Digital Social Forum in a Parkinson’s Disease Risk Cohort: A Thematic Analysis of Forum Messages . Parkinson's Disease vol. 2026 , ( 1 )
Weintraub D, York MK, Dobkin R, Nair AR, Kurth R, Lafontant D-E, Caspell-Garcia C, Alcalay RN et al. ( 2026 ) . Prodromal Lewy body disorder features in REM sleep behavior disorder with synuclein disease .
Li R, Rudd K, Roccati E, Goldberg LR, Bindoff AD, Lawler K, Aiyede M, Simonet C et al. ( 2025 ) . Smartphone self-testing of hand and speech motor functions: a study of reliability and usability in older adults . GeroScience vol. 48 , ( 1 ) 171 - 182 .
Belete D, Mattjie C, Huxford B, Bestwick JP, Noyce AJ, Simonet C ( 2025 ) . Evaluating the Role of α‐Synuclein Seed Amplification as a Disease Progression Marker: Evidence and Uncertainties . Movement Disorders Clinical Practice
Markovic-Obiago Z, Bestwick JP, Chohan H, Schrag A, Simonet C, Noyce AJ ( 2025 ) . Idiopathic hyposmia as a marker of prodromal Parkinson’s disease — a cohort study . Scientific Reports vol. 15 , ( 1 )
Bramich S, Noyce AJ, King AE, Higgins S, Simonet C, Bindoff AD, Naismith SL, Vickers JC et al. ( 2025 ) . The Tasmania-London protocol to detect isolated rapid eye movement sleep behavior disorder using home-based video-polysomnography . Sleep vol. 49 , ( 3 )
Azoidou V, Zirra A, Boyle T, Gallagher D, Noyce AJ, Simonet C ( 2025 ) . Usability, safety and tolerability of CUE1 vibrotactile device as promising therapeutic approach in orthostatic tremor . Clinical Parkinsonism & Related Disorders vol. 13 ,
Huxford B, Simonet C, Pérez‐Carbonell L, Leschziner G, Schrag A, Dobson R, Noyce AJ ( 2025 ) . Plasma Neurofilament Light Chain and TNF‐α Correlate with Motor Features in Isolated REM Sleep Behavior Disorder . Movement Disorders Clinical Practice vol. 12 , ( 11 ) 1961 - 1967 .
Zirra A, Dey KC, Camboe E, Waters S, Haque T, Huxford B, Chohan H, Donkor N et al. ( 2025 ) . The East London Parkinson’s disease project – a case-control study of Parkinson’s Disease in a diverse population . npj Parkinson's Disease vol. 11 , ( 1 )
Bramich S, Noyce AJ, King AE, Higgins S, Simonet C, Naismith SL, Pérez-Carbonell L, Alty J ( 2025 ) . The Tasmania-London (TASLON) 3-step home-based video-polysomnography approach to detect iRBD in the community: protocol and preliminary results .
Azoidou V, Bhadra E, Rowsell K, Camboe E, Dey K, Zirra A, Quah C, Budu C et al. ( 2025 ) . Non-invasive device to alleviate symptoms in people living with Parkinson’s: study protocol for a multicentre phase II double-blind randomised controlled trial . BMJ Open vol. 15 , ( 4 )
Mitchell E, Mattjie C, Bestwick JP, Barros RC, Simonet C ( 2025 ) . Hyposmia in Parkinson’s disease; exploring selective odour loss . npj Parkinson's Disease vol. 11 , ( 1 )
Azoidou V, Rowsell K, Camboe E, Dey KC, Zirra A, Quah C, Boyle T, Gallagher D et al. ( 2025 ) . A pilot interventional study on feasibility and effectiveness of the CUE1 device in Parkinson's disease . Parkinsonism & Related Disorders vol. 133 ,
Mahlknecht P, Leiter S, Horlings C, Schwarzová K, Egner I, Stockner H, Marini K, Theyer C et al. ( 2024 ) . Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study . Movement Disorders Clinical Practice vol. 12 , ( 2 ) 203 - 209 .
Azoidou V, Noyce AJ ( 2024 ) . The effect of tactile cueing on dual task performance in Parkinson’s disease. A systematic review and meta-analysis . Clinical Parkinsonism & Related Disorders vol. 11 ,
Azoidou V, Rowsell K, Camboe E, Dey KC, Zirra A, Quah C, Boyle T, Gallagher D et al. ( 2024 ) . A Pilot Interventional Study on Feasibility and Effectiveness of the CUE1 device in Parkinson’s disease .
Francis M, Zirra A, Haque T, Gallagher D, Budu C ( 2024 ) . Rapid Voluntary Blinking as a Clinical Marker of Parkinson’s Disease . Journal of Parkinson’s Disease vol. 14 , ( 5 ) 993 - 997 .
Simonet C, Pérez‐Carbonell L, Galmés‐Ordinas MA, Huxford BFR, Chohan H, Gill A, Leschziner G ( 2024 ) . The Motor Dysfunction Seen in Isolated REM Sleep Behavior Disorder . Movement Disorders vol. 39 , ( 6 ) 1054 - 1059 .
Simonet C, Compta Y ( 2024 ) . Constipation: “Making” or “Marking” motor and cognitive progression already in prodromal synucleinopathy? . Parkinsonism & Related Disorders vol. 119 ,
Simonet C, Mahlknecht P, Marini K, Seppi K, Gill A, Lees AJ, Giovannoni G, Schrag A ( 2023 ) . The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease . Movement Disorders vol. 38 , ( 9 ) 1636 - 1644 .
Simonet C, Pérez-Carbonell L, Huxford BF, Chohan H, Gill A, Leschziner G, Lees AJ, Schrag A et al. ( 2023 ) . The motor anomalies seen in isolated REM sleep behavior disorder .
Pérez‐Carbonell L, Simonet C, Chohan H, Gill A, Leschziner G ( 2023 ) . The Views of Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder on Risk Disclosure . Movement Disorders vol. 38 , ( 6 ) 1089 - 1093 .
Belete D, Jacobs BM, Simonet C, Bestwick JP, Waters S, Marshall CR, Dobson R, Noyce AJ ( 2023 ) . Association Between Antiepileptic Drugs and Incident Parkinson Disease . JAMA Neurology vol. 80 , ( 2 ) 183 - 187 .
Garrido A, Pérez‐Sisqués L, Simonet C, Campoy‐Campos G, Solana‐Balaguer J, Martín‐Flores N, Fernández M, Soto M et al. ( 2022 ) . Increased Phospho‐AKT in Blood Cells from LRRK2 G2019S Mutation Carriers . Annals of Neurology vol. 92 , ( 5 ) 888 - 894 .
Simonet C, Lambert C, Rees R, Galmes MA ( 2022 ) . 249  Slow motion analysis of repetitive tapping (SMART) test: a new measurement of bradykinesia . Journal of Neurology Neurosurgery & Psychiatry vol. 93 , ( 6 ) a85.2 - a8a85 .
Simonet C, Bestwick J, Jitlal M, Waters S, Ben-Joseph A, Marshall CR, Dobson R, Marrium S et al. ( 2022 ) . Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population . JAMA Neurology vol. 79 , ( 4 ) 359 - 369 .
Garrido A, Santamaría E, Fernández‐Irigoyen J, Soto M, Simonet C, Fernández M, Obiang D, Tolosa E et al. ( 2022 ) . Differential Phospho‐Signatures in Blood Cells Identify LRRK2 G2019S Carriers in Parkinson's Disease . Movement Disorders vol. 37 , ( 5 ) 1004 - 1015 .
Akram N, Li H, Ben-Joseph A, Budu C, Gallagher DA, Bestwick JP, Schrag A, Noyce AJ et al. ( 2022 ) . Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson’s disease: a Distal Finger Tapping test . Scientific Reports vol. 12 , ( 1 )
Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Lees AJ ( 2021 ) . Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm . npj Parkinson's Disease vol. 7 , ( 1 )
Huxford B, Haque T, Joseph AB, Simonet C, Gallagher D, Budu C, Dobson R, Noyce A ( 2021 ) . Parkinson's Disease and Type 2 Diabetes: HbA1c Is Associated with Motor and Cognitive Severity . Movement Disorders vol. 37 , ( 2 ) 427 - 428 .
Simonet C, Noyce AJ ( 2021 ) . Domotics, Smart Homes, and Parkinson’s Disease . Journal of Parkinson’s Disease vol. 11 , ( s1 ) s55 - s63 .
Simonet C ( 2021 ) . Mild parkinsonian signs: the interface between aging and Parkinson’s disease . Advances in Clinical Neuroscience & Rehabilitation vol. 20 ,
Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Lees AJ, Cuzick J ( 2021 ) . Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm . npj Parkinson's Disease vol. 7 , ( 1 )
Simonet C, Galmes MA, Lambert C, Rees RN, Haque T, Bestwick JP, Lees AJ ( 2021 ) . Slow Motion Analysis of Repetitive Tapping (SMART) Test: Measuring Bradykinesia in Recently Diagnosed Parkinson’s Disease and Idiopathic Anosmia . Journal of Parkinson’s Disease vol. 11 , ( 4 ) 1901 - 1915 .
Chahine LM, Brumm MC, Caspell‐Garcia C, Oertel W, Mollenhauer B, Amara A, Fernandez‐Arcos A, Tolosa E et al. ( 2020 ) . Dopamine transporter imaging predicts clinically‐defined α‐synucleinopathy in REM sleep behavior disorder . Annals of Clinical and Translational Neurology vol. 8 , ( 1 ) 201 - 212 .
Akram N, Li H, Ben-Joseph A, Budu C, Noyce AJ ( 2020 ) . Developing and Validating a New Web-Based Tapping Test for Measuring Distal Bradykinesia in Parkinson’s Disease .
Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Giovannoni G ( 2020 ) . Improving estimation of Parkinson’s disease risk - The enhanced PREDICT-PD algorithm .
Painous C, Martí MJ, Simonet C, Garrido A, Valldeoriola F, Muñoz E, Cámara A, Compta Y ( 2020 ) . Prediagnostic motor and non-motor symptoms in progressive supranuclear palsy: The step-back PSP study . Parkinsonism & Related Disorders vol. 74 , 67 - 73 .
Simonet C, Schrag A, Lees AJ ( 2019 ) . The motor prodromes of parkinson’s disease: from bedside observation to large-scale application . Journal of Neurology vol. 268 , ( 6 ) 2099 - 2108 .
Simonet C, Tolosa E, Camara A, Valldeoriola F ( 2019 ) . Emergencies and critical issues in Parkinson’s disease . Practical Neurology vol. 20 , ( 1 ) 15 - 25 .
Azoidou V, Bhadra E, Camboe E, Dey KC, Zirra A, Quah C, Budu C, Boyle T et al. . A Sternum-Worn, Non-Invasive Vibrotactile Device to Alleviate Symptoms in Parkinson’s: a Multi-Site Double-Blind Randomised Controlled Trial .
Torricelli R, Kenny JE, Bache E, Pérez-Carbonell L, Huxford BF, Chohan H, Leschziner G, Alty J et al. . Handwriting patterns in Isolated Rapid Eye Movement Sleep Behaviour Disorder .
Rees RN, Meyer SI, Philpott C, Gane S, McClelland L, Simonet C, Bestwick JP, Noyce AJ et al. . Investigating idiopathic anosmia as a prodromal state of Parkinson’s disease .
Simonet C, Bestwick J, Jitlal M, Ben-Joseph A, Marshall CR, Dobson R, Marrium S, Robson J et al. . Risk factors, early presentations, and clinical markers of Parkinson’s disease in Primary Care in a diverse UK population .
Simonet C, Galmes M, Lambert C, Rees R, Haque T, Bestwick J, Lees A, Schrag A et al. . Slow Motion Analysis of Repetitive Tapping (SMART) test: measuring bradykinesia in recently diagnosed Parkinson’s disease and idiopathic anosmia .
Zirra A, Dey KC, Camboe E, Waters S, Haque T, Huxford B, Chohan H, Donkor N et al. . The East London Parkinson’s Disease Project – A case-control study in a diverse population .
Azoidou V, Zirra A, Boyle T, Gallagher D, Noyce AJ, Simonet C . Usability, Safety and Tolerability of CUE1 Vibrotactile Device as Promising Therapeutic Approach in Orthostatic Tremor .