Publications: DR Ajay Gupta
Faconti L, Tantirige N, Poulter NR, George J, Kapil V, Gupta A, Swift PA, Heagerty A et al.
(
2025
)
.
Call to action: British and Irish hypertension society position statement on blood pressure treatment thresholds and targets
.
Journal of Human Hypertension
vol.
39
,
(
8
)
537
-
540
.
Steckelmacher J, Faconti L, Gupta A
(
2025
)
.
Beyond the Tip of the Iceberg: Rethinking Hypertension Screening in Young Adults
.
Journal of the American Heart Association
vol.
14
,
(
14
)
Article
e042877
,
Danielli M, Garofalidou T, Gupta A, Sever P, Munroe P, Warren H
(
2025
)
.
Hypertensive patients with greater genetic risk respond less effectively to treatment and are more likely to be treatment resistant in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)
.
Clinical Medicine
vol.
25
,
(
4
)
Article
100407
,
100407
-
100407
.
Collett G, Emad A, Gupta AK
(
2025
)
.
The impact of workplace support components on the mental health and burnout of UK-based healthcare professionals: Insights from the CoPE-HCP cohort study
.
Clinical Medicine
vol.
25
,
(
4
)
Article
100324
,
100324
-
100324
.
Danielli M, Moothathamby T, Khanji MY, Wiles K, Gupta A
(
2025
)
.
Current concepts in the management of hypertension in hypertensive disorders of pregnancy: a systematic review of international guidelines
.
European Journal of Preventive Cardiology
Article
zwaf373
,
Sever PS, Rostamian S, Whiteley W, Ariti C, Godec T, Gupta A, Mackay J, Whitehouse A et al.
(
2025
)
.
Long-term benefits of atorvastatin on the incidence of cardiovascular events: the ASCOT-Legacy 20-year follow-up
.
Heart
vol.
111
,
(
16
)
769
-
775
.
Collett G, Kotecha A, Gupta A
(
2025
)
.
Burnout and Depression Among UK-Based Healthcare Professionals
.
Journal of Occupational & Environmental Medicine
vol.
67
,
(
7
)
477
-
482
.
Collett G, Emad A, Gupta AK
(
2025
)
.
Burnout and depression amongst healthcare professionals
.
Occupational Medicine
vol.
74
,
(
9
)
688
-
688
.
Graham C, Steckelmacher J, Capel M, Prasher J, Nicole Pereira N, Ahmed A, Poulter N, Sever P et al.
(
2024
)
.
Nationwide trends in blood pressure control among those with and without diabetes in England over last 2 decades: Health Survey of England 2003-2019
.
European Heart Journal
vol.
45
,
(
Supplement_1
)
Article
ehae666.2561
,
Gupta A, Graham C, Capel M, Steckelmacher J, Prasher J
(
2024
)
.
Nationwide trends in major cardiovascular risk factors in England in the last 2 decades: Health Survey of England 2003-2019
.
European Heart Journal
vol.
45
,
(
Supplement_1
)
Article
ehae666.3603
,
Graham C, Steckelmacher J, Prasher J, Capel M, Ahmed A, Poulter N, Sever P, Gupta A
(
2024
)
.
Trends in hypertension prevalence and control in England over the last 3 decades: Health Survey of England 1994-2019
.
European Heart Journal
vol.
45
,
(
Supplement_1
)
Article
ehae666.2562
,
Steckelmacher J, Graham C, Maniero C, Gupta A
(
2024
)
.
Managing hypertension in older people: current concepts
.
Drug and Therapeutics Bulletin
vol.
62
,
(
10
)
149
-
155
.
Sposato LA, Gupta AK, Wu KC
(
2024
)
.
<i>JAHA</i>\n Spotlight on Neurocardiology: An Emerging Field Gaining Traction Among Neurologists and Cardiologists
.
Journal of the American Heart Association
vol.
13
,
(
17
)
Article
e038026
,
Reith C, Preiss D, Blackwell L, Emberson J, Spata E, Davies K, Halls H, Harper C et al.
(
2024
)
.
Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis
.
The Lancet Diabetes & Endocrinology
vol.
12
,
(
5
)
306
-
319
.
Collett G, Korszun A, Gupta AK
(
2024
)
.
Potential strategies for supporting mental health and mitigating the risk of burnout among healthcare professionals: insights from the COVID-19 pandemic
.
eClinicalMedicine
vol.
71
,
Article
102562
,
102562
-
102562
.
Magavern EF, Kapil V, Saxena M, Gupta A, Caulfield MJ
(
2024
)
.
Use of Genomics to Develop Novel Therapeutics and Personalize Hypertension Therapy
.
Arteriosclerosis, Thrombosis, and Vascular Biology
vol.
44
,
(
4
)
784
-
793
.
Gupta A, Whiteley WN, Godec T, Rostamian S, Ariti C, Mackay J, Whitehouse A, Janani L et al.
(
2024
)
.
Legacy benefits of blood pressure treatment on cardiovascular events are primarily mediated by improved blood pressure variability: the ASCOT trial
.
European Heart Journal
vol.
45
,
(
13
)
1159
-
1169
.
Bidel Z, Nazarzadeh M, Canoy D, Copland E, Gerdts E, Woodward M, Gupta AK, Reid CM et al.
(
2023
)
.
Sex-Specific Effects of Blood Pressure Lowering Pharmacotherapy for the Prevention of Cardiovascular Disease: An Individual Participant-Level Data Meta-Analysis
.
Hypertension
vol.
80
,
(
11
)
2293
-
2302
.
Wu R, Williams C, Zhou J, Schlackow I, Emberson J, Reith C, Keech A, Robson J et al.
(
2023
)
.
Long-term cardiovascular risks and the impact of statin treatment on socioeconomic inequalities: a microsimulation model
.
British Journal of General Practice
vol.
74
,
(
740
)
e189
-
e198
.
Maniero C, Ng SM, Collett G, Godec T, Siddiqui I, Antoniou S, Kumar A, Janmohamed A et al.
(
2023
)
.
Differential impact of COVID-19 on mental health and burnout
.
Occupational Medicine
vol.
74
,
(
1
)
45
-
52
.
Collett G, Godec T, Gupta AK
(
2023
)
.
Factors influencing attitudes toward vaccine safety and vaccine effectiveness amongst UK healthcare professionals prior to and at the time of COVID-19 vaccine rollout: Insights from the CoPE-HCP cohort study
.
Human Vaccines & Immunotherapeutics
vol.
19
,
(
1
)
Article
2188823
,
Siddiqui I, Gupta J, Collett G, McIntosh I, Komodromos C, Godec T, Ng S, Maniero C et al.
(
2023
)
.
Perceived workplace support and mental health, well-being and burnout among health care professionals during the COVID-19 pandemic: a cohort analysis
.
CMAJ Open
vol.
11
,
(
1
)
E191
-
E200
.
Khanji MY, Collett G, Godec T, Maniero C, Ng SM, Siddiqui I, Gupta J, Kapil V et al.
(
2023
)
.
Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study
.
General Psychiatry
vol.
36
,
(
1
)
e100908
-
e100908
.
Sever P, Gupta A, Whiteley W, Godec T, Rostamian S, Mackay J, Poulter N, Whitehouse A
(
2023
)
.
S-28-8: THE ASCOT LEGACY COHORT: THE LONG-TERM EFFECTS OF BLOOD PRESSURE AND BLOOD PRESSURE VARIABILITY ON CARDIOVASCULAR AND RENAL OUTCOMES
.
Journal of Hypertension
vol.
41
,
(
Suppl 1
)
e67
-
e68
.
Kapil V, Collett G, Godec T, Gupta J, Maniero C, Ng SM, McIntosh I, Kumar A et al.
(
2022
)
.
Longitudinal comparisons of mental health, burnout and well-being in patient-facing, non-patient-facing healthcare professionals and non-healthcare professionals during the COVID-19 pandemic: findings from the CoPE-HCP study
.
BJPsych Open
vol.
8
,
(
5
)
Article
e173
,
Rostamian S, Godec T, Gupta AK, Whiteley W, Mackay J, Whitehouse A, Sever P
(
2022
)
.
Abstract P325: Visit-To-Visit Blood Pressure Variability Is A Major Risk Factor For Renal Outcomes In Hypertensive Patients: Evidence From The 20-Year Follow-Up Of The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)
.
Hypertension
vol.
79
,
(
Suppl_1
)
Nazarzadeh M, Bidel Z, Canoy D, Copland E, Bennett DA, Dehghan A, Davey Smith G, Holman RR et al.
(
2022
)
.
Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis
.
The Lancet Diabetes & Endocrinology
vol.
10
,
(
9
)
645
-
654
.
Reith C, Baigent C, Blackwell L, Emberson J, Spata E, Davies K, Halls H, Holland L et al.
(
2022
)
.
Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials
.
The Lancet
vol.
400
,
(
10355
)
832
-
845
.
Maniero C, Lopuszko A, Papalois K-B, Gupta A, Kapil V, Khanji MY
(
2022
)
.
Non-pharmacological factors for hypertension management: a systematic review of international guidelines
.
European Journal of Preventive Cardiology
vol.
30
,
(
1
)
17
-
33
.
Cholesterol Treatment Trialists’ Collaboration
(
2022
)
.
Harmonisation of large-scale, heterogeneous individual participant adverse event data from randomised trials of statin therapy
.
Clinical Trials
vol.
19
,
(
6
)
593
-
604
.
Kottke TE, Gupta AK, Thomas RJ
(
2022
)
.
Failing Cardiovascular Health
.
Journal of the American College of Cardiology
vol.
80
,
(
2
)
152
-
154
.
Oggero S, Godec T, van Gorp R, Pinto AL, Schurgers LJ, Reutelingsperger C, Sever P, Norling LV et al.
(
2022
)
.
Role of plasma extracellular vesicles in prediction of cardiovascular risk and alterations in response to statin therapy in hypertensive patients
.
Journal of Hypertension
vol.
40
,
(
8
)
1522
-
1529
.
George M, Gupta A
(
2022
)
.
Blood Pressure–Lowering Effects of Omega‐3 Polyunsaturated Fatty Acids: Are These the Missing Link to Explain the Relationship Between Omega‐3 Polyunsaturated Fatty Acids and Cardiovascular Disease?
.
Journal of the American Heart Association
vol.
11
,
(
11
)
Article
e026258
,
Siddiqui I, Gupta J, McIntosh I, Komodromos C, Godec T, Collett G, Ng S, Maniero C et al.
(
2022
)
.
The Relationship Between Availability and Changes to Perceived Workplace Support and Their Impact on the Mental Health, Well-being and Burn-Out of Healthcare Professionals (HCP): Insight and Mitigating Strategies From the CoPE-HCP Cohort Study
.
Ng SM, Pan J, Mouyis K, Kondapally Seshasai SR, Kapil V, Rice KM, Gupta AK
(
2022
)
.
Quantifying the Excess Risk of Adverse COVID-19 Outcomes in Unvaccinated Individuals With Diabetes Mellitus, Hypertension, Ischaemic Heart Disease or Myocardial Injury: A Meta-Analysis
.
Frontiers in Cardiovascular Medicine
vol.
9
,
Article
871151
,
Ng SM, Pan J, Gupta AK
(
2022
)
.
Poor achievement of lipid targets after acute coronary syndrome: what can we improve?
.
Medical Journal of Australia
vol.
216
,
(
9
)
458
-
459
.
Boulestreau R, van den Born BH, Lip GYH, Gupta A
(
2022
)
.
Malignant Hypertension: Current Perspectives and Challenges
.
Journal of the American Heart Association
vol.
11
,
(
7
)
Article
e023397
,
Canoy D, Copland E, Nazarzadeh M, Ramakrishnan R, Pinho-Gomes A-C, Salam A, Dwyer JP, Farzadfar F et al.
(
2022
)
.
Antihypertensive drug effects on long-term blood pressure: an individual-level data meta-analysis of randomised clinical trials
.
Heart
vol.
108
,
(
16
)
1281
-
1289
.
Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP et al.
(
2021
)
.
Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide
.
British Journal of Pharmacology
vol.
179
,
(
20
)
4757
-
4777
.
Whiteley WN, Gupta AK, Godec T, Rostamian S, Whitehouse A, Mackay J, Sever PS
(
2021
)
.
Long-Term Incidence of Stroke and Dementia in ASCOT
.
Stroke
vol.
52
,
(
10
)
3088
-
3096
.
Rahimi K, Bidel Z, Nazarzadeh M, Copland E, Canoy D, Wamil M, Majert J, McManus R et al.
(
2021
)
.
Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis
.
The Lancet
vol.
398
,
(
10305
)
1053
-
1064
.
Chong JH, Chahal CAA, Gupta A, Ricci F, Westwood M, Pugliese F, Petersen SE, Khanji MY
(
2021
)
.
COVID-19 and the Digitalisation of Cardiovascular Training and Education—A Review of Guiding Themes for Equitable and Effective Post-graduate Telelearning
.
Frontiers in Cardiovascular Medicine
vol.
8
,
Article
666119
,
Gupta AK
(
2021
)
.
<i>JAHA</i>\n Spotlight on Air Pollution and Cardiovascular Disease: A Call for Urgent Action
.
Journal of the American Heart Association
vol.
10
,
(
10
)
Article
e022209
,
Rahimi K, Bidel Z, Nazarzadeh M, Copland E, Canoy D, Ramakrishnan R, Pinho-Gomes A-C, Woodward M et al.
(
2021
)
.
Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis
.
The Lancet
vol.
397
,
(
10285
)
1625
-
1636
.
Copland E, Canoy D, Nazarzadeh M, Bidel Z, Ramakrishnan R, Woodward M, Chalmers J, Teo KK et al.
(
2021
)
.
Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis
.
The Lancet Oncology
vol.
22
,
(
4
)
558
-
570
.
Harvey G, Godec T, Kapil V, Mackay J, Whitehouse A, Poulter N, Sever PS, Gupta A
(
2021
)
.
COMPARING THE DISCRIMINATIVE ABILITY OF DIFFERENT ELECTROGRAPHIC CRITERIA FOR LEFT VENTRICULAR HYPERTROPHY IN PREDICTING CARDIOVASCULAR EVENTS IN HYPERTENSIVE PATIENTS
.
Journal of Hypertension
.
vol.
39
,
e165
-
e166
.
Warren H, Traylor M, Garofalidou T, Ng FL, Gupta A, Sever P, Caulfield M, Munroe P
(
2021
)
.
HYPERTENSIVE PATIENTS WITH GREATER GENETIC RISK RESPOND LESS EFFECTIVELY TO TREATMENT AND ARE MORE LIKELY TO BE TREATMENT RESISTANT
.
Journal of Hypertension
vol.
39
,
(
Supplement 1
)
e359
-
e359
.
Gupta A, Godec T, Mackay J, Whitehouse A, Rostamian S, Collier T, Poulter N, Sever P
(
2021
)
.
INFLUENCE OF AGE, SEX AND AN OCCURRENCE OF CARDIOVASCULAR EVENT ON SEASONAL VARIATIONS IN BLOOD PRESSURES IN HYPERTENSIVE PATIENTS: INSIGHTS FROM THE ASCOT COHORT
.
Journal of Hypertension
.
vol.
39
,
e145
-
e146
.
Gupta A, Whiteley W, Godec T, Rostamian S, Whitehouse A, Mackay J, Sever P
(
2021
)
.
LONG TERM BENEFITS OF BLOOD PRESSURE TREATMENT ON THE INCIDENCE OF ATRIAL FIBRILLATION, HEART FAILURE AND CARDIOVASCULAR MORBIDITY AND MORTALITY: 20-YEARS FOLLOW-UP OF ASCOT-LEGACY
.
Journal of Hypertension
.
vol.
39
,
e8
-
e8
.
Gupta A, Rostamian S, Mackay J, Godec T, Whitehouse A, Poulter N, Sever P
(
2021
)
.
THE DEVELOPMENT OF RESISTANT HYPERTENSION INDEPENDENT OF THE PRECEDING PERIOD OF THE BLOOD PRESSURE CONTROL IS ASSOCIATED WITH THE INCREASED RISK OF CARDIOVASCULAR EVENTS AND DEATH
.
Journal of Hypertension
.
vol.
39
,
e358
-
e358
.
Gupta A, Whiteley W, Godec T, Rostamian S, Mackay J, Whitehouse A, Sever P
(
2021
)
.
THE RELATIONSHIP BETWEEN BP-CONTROL, BP -VARIABILITY AND ANTIHYPERTENSIVE TREATMENT WITH THE LONG-TERM RISK OF CARDIOVASCULAR EVENT: LESSONS FROM THE ASCOT-LEGACY 20 YEAR FOLLOW-UP
.
Journal of Hypertension
.
vol.
39
,
e148
-
e148
.
Khanji MY, Maniero C, NG S, Siddiqui I, Gupta J, Crosby L, Antoniou S, Khan R et al.
(
2021
)
.
Early and Mid-Term Implications of the COVID-19 Pandemic on the Physical, Behavioral and Mental Health of Healthcare Professionals: The CoPE-HCP Study Protocol
.
Frontiers in Psychology
vol.
12
,
Article
616280
,
Siddiqui I, Aurelio M, Gupta A, Blythe J, Khanji MY
(
2021
)
.
COVID-19: Causes of anxiety and wellbeing support needs of healthcare professionals in the UK: A cross-sectional survey
.
Clinical Medicine
vol.
21
,
(
1
)
66
-
72
.
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S et al.
(
2021
)
.
The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction
.
AMERICAN JOURNAL OF CARDIOVASCULAR DISEASE
vol.
11
,
(
5
)
659
-
+
.
London B, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K et al.
(
2020
)
.
Diversity, Equity, and Inclusiveness in Medicine and Cardiology: Next Steps for\n <i>JAHA</i>
.
Journal of the American Heart Association
vol.
9
,
(
20
)
Article
e019307
,
Simon MA, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K et al.
(
2020
)
.
Equity, Diversity, and Inclusiveness in Cardiovascular Medicine and Health Care
.
Journal of the American Heart Association
vol.
9
,
(
20
)
Article
e019137
,
Gupta AK, Jneid H, Addison D, Ardehali H, Boehme AK, Borgaonkar S, Boulestreau R, Clerkin K et al.
(
2020
)
.
Current Perspectives on Coronavirus Disease 2019 and Cardiovascular Disease: A White Paper by the\n <i>JAHA</i>\n Editors
.
Journal of the American Heart Association
vol.
9
,
(
12
)
Article
e017013
,
Sinha S, Ghosh B, Bandyopadhyay S, Fatima F, Bandi VK, Thakur P, Reddy B, Chary S et al.
(
2020
)
.
Comparative evaluation of efficacy, pharmacodynamics, and safety of Hetero’s adalimumab (Mabura®, Hetero Biopharma Ltd.) and reference adalimumab (Humira®, Abbvie Inc.) in patients with active rheumatoid arthritis on concomitant methotrexate therapy
.
BMC Rheumatology
vol.
4
,
(
1
)
Article
24
,
Kapil V, Gupta AK
(
2020
)
.
Solar UV Radiation: A Potential Modifiable Risk Factor for Hypertension
.
Journal of the American Heart Association
vol.
9
,
(
5
)
Article
e015627
,
Cabrera CP, Ng FL, Nicholls HL, Gupta A, Barnes MR, Munroe PB, Caulfield MJ
(
2019
)
.
Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicated
.
Human Molecular Genetics
vol.
28
,
(
R2
)
R151
-
R161
.
MANIERO C, GUPTA AK, LOBO MD
(
2019
)
.
Impact of the New ACC/AHA and ESC/ESH Hypertension Guidelines in the UK
.
European Heart Journal
vol.
40
,
(
30
)
2472
-
2475
.
Rahimi K, Canoy D, Nazarzadeh M, Salimi-Khorshidi G, Woodward M, Teo K, Davis BR, Chalmers J et al.
(
2019
)
.
Investigating the stratified efficacy and safety of pharmacological blood pressure-lowering: an overall protocol for individual patient-level data meta-analyses of over 300 000 randomised participants in the new phase of the Blood Pressure Lowering Treatment Trialists’ Collaboration (BPLTTC)
.
BMJ Open
vol.
9
,
(
5
)
e028698
-
e028698
.
Poulter NR, Dolan E, Gupta AK, O’Brien E, Whitehouse A, Sever PS
(
2019
)
.
Efficacy and Safety of Incremental Dosing of a New Single-Pill Formulation of Perindopril and Amlodipine in the Management of Hypertension
.
American Journal of Cardiovascular Drugs
vol.
19
,
(
3
)
313
-
323
.
Berkelmans GFN, Gudbjörnsdottir S, Visseren FLJ, Wild SH, Franzen S, Chalmers J, Davis BR, Poulter NR et al.
(
2019
)
.
Prediction of individual life-years gained without cardiovascular events from lipid, blood pressure, glucose, and aspirin treatment based on data of more than 500 000 patients with Type 2 diabetes mellitus
.
European Heart Journal
vol.
40
,
(
34
)
2899
-
2906
.
Gupta AK, Sen S, Kumari R, Chakraborty DP, Kumar A
(
2019
)
.
Influence of weathering on coking properties of coals used in coke making
.
Impc 2018 29th International Mineral Processing Congress
.
124
-
130
.
Gupta A, Mackay J, Whitehouse A, Godec T, Collier T, Poulter N, Sever P
(
2018
)
.
A17615 Baseline predictors of all-cause- and cardiovascular- mortality amongst 8580 hypertensive patients followed up for 16 years in the ASCOT legacy study
.
Journal of Hypertension
.
vol.
36
,
e251
-
e251
.
Pushpasekaran N, Gupta D, Kashyap A, Arora S, Gupta AK
(
2018
)
.
Concomitant methicillin-resistant Staphylococcus aureus infection in tubercular sacroiliitis masquerading as anti-tubercular drug resistance: Role for molecular diagnosis
.
Indian Journal of Tuberculosis
vol.
65
,
(
4
)
350
-
355
.
Gupta A, Mackay J, Whitehouse A, Godec T, Collier T, Pocock S, Poulter N, Sever P
(
2018
)
.
Long-term mortality after blood pressure-lowering and lipid-lowering treatment in patients with hypertension in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Legacy study: 16-year follow-up results of a randomised factorial trial
.
The Lancet
vol.
392
,
(
10153
)
1127
-
1137
.
Saxena M, Shour T, Shah M, Wolff CB, Julu POO, Kapil V, Collier DJ, Ng FL et al.
(
2018
)
.
Attenuation of Splanchnic Autotransfusion Following Noninvasive Ultrasound Renal Denervation: A Novel Marker of Procedural Success
.
Journal of the American Heart Association
vol.
7
,
(
12
)
Article
e009151
,
McGlone ER, Gupta AK, Reddy M, Khan OA
(
2018
)
.
Antral resection versus antral preservation during laparoscopic sleeve gastrectomy for severe obesity: Systematic review and meta-analysis
.
Surgery for Obesity and Related Diseases
vol.
14
,
(
6
)
857
-
864
.
Gupta A, Mackay J, Whitehouse A, Godec T, Collier T, Poulter N, Sever P
(
2018
)
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