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Research

Publications: DR Ajay Gupta

Faconti L, Tantirige N, Poulter NR, George J, Kapil V, Gupta A, Swift PA, Heagerty A et al. ( 2025 ) . Call to action: British and Irish hypertension society position statement on blood pressure treatment thresholds and targets . Journal of Human Hypertension vol. 39 , ( 8 ) 537 - 540 .
Steckelmacher J, Faconti L, Gupta A ( 2025 ) . Beyond the Tip of the Iceberg: Rethinking Hypertension Screening in Young Adults . Journal of the American Heart Association vol. 14 , ( 14 ) Article e042877 ,
Danielli M, Garofalidou T, Gupta A, Sever P, Munroe P, Warren H ( 2025 ) . Hypertensive patients with greater genetic risk respond less effectively to treatment and are more likely to be treatment resistant in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) . Clinical Medicine vol. 25 , ( 4 ) Article 100407 , 100407 - 100407 .
Collett G, Emad A, Gupta AK ( 2025 ) . The impact of workplace support components on the mental health and burnout of UK-based healthcare professionals: Insights from the CoPE-HCP cohort study . Clinical Medicine vol. 25 , ( 4 ) Article 100324 , 100324 - 100324 .
Danielli M, Moothathamby T, Khanji MY, Wiles K, Gupta A ( 2025 ) . Current concepts in the management of hypertension in hypertensive disorders of pregnancy: a systematic review of international guidelines . European Journal of Preventive Cardiology Article zwaf373 ,
Sever PS, Rostamian S, Whiteley W, Ariti C, Godec T, Gupta A, Mackay J, Whitehouse A et al. ( 2025 ) . Long-term benefits of atorvastatin on the incidence of cardiovascular events: the ASCOT-Legacy 20-year follow-up . Heart vol. 111 , ( 16 ) 769 - 775 .
Collett G, Kotecha A, Gupta A ( 2025 ) . Burnout and Depression Among UK-Based Healthcare Professionals . Journal of Occupational & Environmental Medicine vol. 67 , ( 7 ) 477 - 482 .
Collett G, Emad A, Gupta AK ( 2025 ) . Burnout and depression amongst healthcare professionals . Occupational Medicine vol. 74 , ( 9 ) 688 - 688 .
Graham C, Steckelmacher J, Capel M, Prasher J, Nicole Pereira N, Ahmed A, Poulter N, Sever P et al. ( 2024 ) . Nationwide trends in blood pressure control among those with and without diabetes in England over last 2 decades: Health Survey of England 2003-2019 . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.2561 ,
Gupta A, Graham C, Capel M, Steckelmacher J, Prasher J ( 2024 ) . Nationwide trends in major cardiovascular risk factors in England in the last 2 decades: Health Survey of England 2003-2019 . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.3603 ,
Graham C, Steckelmacher J, Prasher J, Capel M, Ahmed A, Poulter N, Sever P, Gupta A ( 2024 ) . Trends in hypertension prevalence and control in England over the last 3 decades: Health Survey of England 1994-2019 . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.2562 ,
Steckelmacher J, Graham C, Maniero C, Gupta A ( 2024 ) . Managing hypertension in older people: current concepts . Drug and Therapeutics Bulletin vol. 62 , ( 10 ) 149 - 155 .
Sposato LA, Gupta AK, Wu KC ( 2024 ) . <i>JAHA</i>\n Spotlight on Neurocardiology: An Emerging Field Gaining Traction Among Neurologists and Cardiologists . Journal of the American Heart Association vol. 13 , ( 17 ) Article e038026 ,
Reith C, Preiss D, Blackwell L, Emberson J, Spata E, Davies K, Halls H, Harper C et al. ( 2024 ) . Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis . The Lancet Diabetes &amp; Endocrinology vol. 12 , ( 5 ) 306 - 319 .
Collett G, Korszun A, Gupta AK ( 2024 ) . Potential strategies for supporting mental health and mitigating the risk of burnout among healthcare professionals: insights from the COVID-19 pandemic . eClinicalMedicine vol. 71 , Article 102562 , 102562 - 102562 .
Magavern EF, Kapil V, Saxena M, Gupta A, Caulfield MJ ( 2024 ) . Use of Genomics to Develop Novel Therapeutics and Personalize Hypertension Therapy . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 44 , ( 4 ) 784 - 793 .
Gupta A, Whiteley WN, Godec T, Rostamian S, Ariti C, Mackay J, Whitehouse A, Janani L et al. ( 2024 ) . Legacy benefits of blood pressure treatment on cardiovascular events are primarily mediated by improved blood pressure variability: the ASCOT trial . European Heart Journal vol. 45 , ( 13 ) 1159 - 1169 .
Bidel Z, Nazarzadeh M, Canoy D, Copland E, Gerdts E, Woodward M, Gupta AK, Reid CM et al. ( 2023 ) . Sex-Specific Effects of Blood Pressure Lowering Pharmacotherapy for the Prevention of Cardiovascular Disease: An Individual Participant-Level Data Meta-Analysis . Hypertension vol. 80 , ( 11 ) 2293 - 2302 .
Wu R, Williams C, Zhou J, Schlackow I, Emberson J, Reith C, Keech A, Robson J et al. ( 2023 ) . Long-term cardiovascular risks and the impact of statin treatment on socioeconomic inequalities: a microsimulation model . British Journal of General Practice vol. 74 , ( 740 ) e189 - e198 .
Maniero C, Ng SM, Collett G, Godec T, Siddiqui I, Antoniou S, Kumar A, Janmohamed A et al. ( 2023 ) . Differential impact of COVID-19 on mental health and burnout . Occupational Medicine vol. 74 , ( 1 ) 45 - 52 .
Collett G, Godec T, Gupta AK ( 2023 ) . Factors influencing attitudes toward vaccine safety and vaccine effectiveness amongst UK healthcare professionals prior to and at the time of COVID-19 vaccine rollout: Insights from the CoPE-HCP cohort study . Human Vaccines &amp; Immunotherapeutics vol. 19 , ( 1 ) Article 2188823 ,
Siddiqui I, Gupta J, Collett G, McIntosh I, Komodromos C, Godec T, Ng S, Maniero C et al. ( 2023 ) . Perceived workplace support and mental health, well-being and burnout among health care professionals during the COVID-19 pandemic: a cohort analysis . CMAJ Open vol. 11 , ( 1 ) E191 - E200 .
Khanji MY, Collett G, Godec T, Maniero C, Ng SM, Siddiqui I, Gupta J, Kapil V et al. ( 2023 ) . Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study . General Psychiatry vol. 36 , ( 1 ) e100908 - e100908 .
Sever P, Gupta A, Whiteley W, Godec T, Rostamian S, Mackay J, Poulter N, Whitehouse A ( 2023 ) . S-28-8: THE ASCOT LEGACY COHORT: THE LONG-TERM EFFECTS OF BLOOD PRESSURE AND BLOOD PRESSURE VARIABILITY ON CARDIOVASCULAR AND RENAL OUTCOMES . Journal of Hypertension vol. 41 , ( Suppl 1 ) e67 - e68 .
Kapil V, Collett G, Godec T, Gupta J, Maniero C, Ng SM, McIntosh I, Kumar A et al. ( 2022 ) . Longitudinal comparisons of mental health, burnout and well-being in patient-facing, non-patient-facing healthcare professionals and non-healthcare professionals during the COVID-19 pandemic: findings from the CoPE-HCP study . BJPsych Open vol. 8 , ( 5 ) Article e173 ,
Rostamian S, Godec T, Gupta AK, Whiteley W, Mackay J, Whitehouse A, Sever P ( 2022 ) . Abstract P325: Visit-To-Visit Blood Pressure Variability Is A Major Risk Factor For Renal Outcomes In Hypertensive Patients: Evidence From The 20-Year Follow-Up Of The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) . Hypertension vol. 79 , ( Suppl_1 )
Nazarzadeh M, Bidel Z, Canoy D, Copland E, Bennett DA, Dehghan A, Davey Smith G, Holman RR et al. ( 2022 ) . Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis . The Lancet Diabetes &amp; Endocrinology vol. 10 , ( 9 ) 645 - 654 .
Reith C, Baigent C, Blackwell L, Emberson J, Spata E, Davies K, Halls H, Holland L et al. ( 2022 ) . Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials . The Lancet vol. 400 , ( 10355 ) 832 - 845 .
Maniero C, Lopuszko A, Papalois K-B, Gupta A, Kapil V, Khanji MY ( 2022 ) . Non-pharmacological factors for hypertension management: a systematic review of international guidelines . European Journal of Preventive Cardiology vol. 30 , ( 1 ) 17 - 33 .
Cholesterol Treatment Trialists’ Collaboration ( 2022 ) . Harmonisation of large-scale, heterogeneous individual participant adverse event data from randomised trials of statin therapy . Clinical Trials vol. 19 , ( 6 ) 593 - 604 .
Kottke TE, Gupta AK, Thomas RJ ( 2022 ) . Failing Cardiovascular Health . Journal of the American College of Cardiology vol. 80 , ( 2 ) 152 - 154 .
Oggero S, Godec T, van Gorp R, Pinto AL, Schurgers LJ, Reutelingsperger C, Sever P, Norling LV et al. ( 2022 ) . Role of plasma extracellular vesicles in prediction of cardiovascular risk and alterations in response to statin therapy in hypertensive patients . Journal of Hypertension vol. 40 , ( 8 ) 1522 - 1529 .
George M, Gupta A ( 2022 ) . Blood Pressure–Lowering Effects of Omega‐3 Polyunsaturated Fatty Acids: Are These the Missing Link to Explain the Relationship Between Omega‐3 Polyunsaturated Fatty Acids and Cardiovascular Disease? . Journal of the American Heart Association vol. 11 , ( 11 ) Article e026258 ,
Siddiqui I, Gupta J, McIntosh I, Komodromos C, Godec T, Collett G, Ng S, Maniero C et al. ( 2022 ) . The Relationship Between Availability and Changes to Perceived Workplace Support and Their Impact on the Mental Health, Well-being and Burn-Out of Healthcare Professionals (HCP): Insight and Mitigating Strategies From the CoPE-HCP Cohort Study .
Ng SM, Pan J, Mouyis K, Kondapally Seshasai SR, Kapil V, Rice KM, Gupta AK ( 2022 ) . Quantifying the Excess Risk of Adverse COVID-19 Outcomes in Unvaccinated Individuals With Diabetes Mellitus, Hypertension, Ischaemic Heart Disease or Myocardial Injury: A Meta-Analysis . Frontiers in Cardiovascular Medicine vol. 9 , Article 871151 ,
Ng SM, Pan J, Gupta AK ( 2022 ) . Poor achievement of lipid targets after acute coronary syndrome: what can we improve? . Medical Journal of Australia vol. 216 , ( 9 ) 458 - 459 .
Boulestreau R, van den Born BH, Lip GYH, Gupta A ( 2022 ) . Malignant Hypertension: Current Perspectives and Challenges . Journal of the American Heart Association vol. 11 , ( 7 ) Article e023397 ,
Canoy D, Copland E, Nazarzadeh M, Ramakrishnan R, Pinho-Gomes A-C, Salam A, Dwyer JP, Farzadfar F et al. ( 2022 ) . Antihypertensive drug effects on long-term blood pressure: an individual-level data meta-analysis of randomised clinical trials . Heart vol. 108 , ( 16 ) 1281 - 1289 .
Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP et al. ( 2021 ) . Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide . British Journal of Pharmacology vol. 179 , ( 20 ) 4757 - 4777 .
Whiteley WN, Gupta AK, Godec T, Rostamian S, Whitehouse A, Mackay J, Sever PS ( 2021 ) . Long-Term Incidence of Stroke and Dementia in ASCOT . Stroke vol. 52 , ( 10 ) 3088 - 3096 .
Rahimi K, Bidel Z, Nazarzadeh M, Copland E, Canoy D, Wamil M, Majert J, McManus R et al. ( 2021 ) . Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis . The Lancet vol. 398 , ( 10305 ) 1053 - 1064 .
Chong JH, Chahal CAA, Gupta A, Ricci F, Westwood M, Pugliese F, Petersen SE, Khanji MY ( 2021 ) . COVID-19 and the Digitalisation of Cardiovascular Training and Education—A Review of Guiding Themes for Equitable and Effective Post-graduate Telelearning . Frontiers in Cardiovascular Medicine vol. 8 , Article 666119 ,
Gupta AK ( 2021 ) . <i>JAHA</i>\n Spotlight on Air Pollution and Cardiovascular Disease: A Call for Urgent Action . Journal of the American Heart Association vol. 10 , ( 10 ) Article e022209 ,
Rahimi K, Bidel Z, Nazarzadeh M, Copland E, Canoy D, Ramakrishnan R, Pinho-Gomes A-C, Woodward M et al. ( 2021 ) . Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis . The Lancet vol. 397 , ( 10285 ) 1625 - 1636 .
Copland E, Canoy D, Nazarzadeh M, Bidel Z, Ramakrishnan R, Woodward M, Chalmers J, Teo KK et al. ( 2021 ) . Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis . The Lancet Oncology vol. 22 , ( 4 ) 558 - 570 .
Harvey G, Godec T, Kapil V, Mackay J, Whitehouse A, Poulter N, Sever PS, Gupta A ( 2021 ) . COMPARING THE DISCRIMINATIVE ABILITY OF DIFFERENT ELECTROGRAPHIC CRITERIA FOR LEFT VENTRICULAR HYPERTROPHY IN PREDICTING CARDIOVASCULAR EVENTS IN HYPERTENSIVE PATIENTS . Journal of Hypertension . vol. 39 , e165 - e166 .
Warren H, Traylor M, Garofalidou T, Ng FL, Gupta A, Sever P, Caulfield M, Munroe P ( 2021 ) . HYPERTENSIVE PATIENTS WITH GREATER GENETIC RISK RESPOND LESS EFFECTIVELY TO TREATMENT AND ARE MORE LIKELY TO BE TREATMENT RESISTANT . Journal of Hypertension vol. 39 , ( Supplement 1 ) e359 - e359 .
Gupta A, Godec T, Mackay J, Whitehouse A, Rostamian S, Collier T, Poulter N, Sever P ( 2021 ) . INFLUENCE OF AGE, SEX AND AN OCCURRENCE OF CARDIOVASCULAR EVENT ON SEASONAL VARIATIONS IN BLOOD PRESSURES IN HYPERTENSIVE PATIENTS: INSIGHTS FROM THE ASCOT COHORT . Journal of Hypertension . vol. 39 , e145 - e146 .
Gupta A, Whiteley W, Godec T, Rostamian S, Whitehouse A, Mackay J, Sever P ( 2021 ) . LONG TERM BENEFITS OF BLOOD PRESSURE TREATMENT ON THE INCIDENCE OF ATRIAL FIBRILLATION, HEART FAILURE AND CARDIOVASCULAR MORBIDITY AND MORTALITY: 20-YEARS FOLLOW-UP OF ASCOT-LEGACY . Journal of Hypertension . vol. 39 , e8 - e8 .
Gupta A, Rostamian S, Mackay J, Godec T, Whitehouse A, Poulter N, Sever P ( 2021 ) . THE DEVELOPMENT OF RESISTANT HYPERTENSION INDEPENDENT OF THE PRECEDING PERIOD OF THE BLOOD PRESSURE CONTROL IS ASSOCIATED WITH THE INCREASED RISK OF CARDIOVASCULAR EVENTS AND DEATH . Journal of Hypertension . vol. 39 , e358 - e358 .
Gupta A, Whiteley W, Godec T, Rostamian S, Mackay J, Whitehouse A, Sever P ( 2021 ) . THE RELATIONSHIP BETWEEN BP-CONTROL, BP -VARIABILITY AND ANTIHYPERTENSIVE TREATMENT WITH THE LONG-TERM RISK OF CARDIOVASCULAR EVENT: LESSONS FROM THE ASCOT-LEGACY 20 YEAR FOLLOW-UP . Journal of Hypertension . vol. 39 , e148 - e148 .
Khanji MY, Maniero C, NG S, Siddiqui I, Gupta J, Crosby L, Antoniou S, Khan R et al. ( 2021 ) . Early and Mid-Term Implications of the COVID-19 Pandemic on the Physical, Behavioral and Mental Health of Healthcare Professionals: The CoPE-HCP Study Protocol . Frontiers in Psychology vol. 12 , Article 616280 ,
Siddiqui I, Aurelio M, Gupta A, Blythe J, Khanji MY ( 2021 ) . COVID-19: Causes of anxiety and wellbeing support needs of healthcare professionals in the UK: A cross-sectional survey . Clinical Medicine vol. 21 , ( 1 ) 66 - 72 .
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S et al. ( 2021 ) . The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction . AMERICAN JOURNAL OF CARDIOVASCULAR DISEASE vol. 11 , ( 5 ) 659 - + .
London B, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K et al. ( 2020 ) . Diversity, Equity, and Inclusiveness in Medicine and Cardiology: Next Steps for\n <i>JAHA</i> . Journal of the American Heart Association vol. 9 , ( 20 ) Article e019307 ,
Simon MA, Ahmad F, Eitzman DT, Gupta AK, Jneid H, Peterson P, Remme CA, Rice K et al. ( 2020 ) . Equity, Diversity, and Inclusiveness in Cardiovascular Medicine and Health Care . Journal of the American Heart Association vol. 9 , ( 20 ) Article e019137 ,
Gupta AK, Jneid H, Addison D, Ardehali H, Boehme AK, Borgaonkar S, Boulestreau R, Clerkin K et al. ( 2020 ) . Current Perspectives on Coronavirus Disease 2019 and Cardiovascular Disease: A White Paper by the\n <i>JAHA</i>\n Editors . Journal of the American Heart Association vol. 9 , ( 12 ) Article e017013 ,
Sinha S, Ghosh B, Bandyopadhyay S, Fatima F, Bandi VK, Thakur P, Reddy B, Chary S et al. ( 2020 ) . Comparative evaluation of efficacy, pharmacodynamics, and safety of Hetero’s adalimumab (Mabura®, Hetero Biopharma Ltd.) and reference adalimumab (Humira®, Abbvie Inc.) in patients with active rheumatoid arthritis on concomitant methotrexate therapy . BMC Rheumatology vol. 4 , ( 1 ) Article 24 ,
Kapil V, Gupta AK ( 2020 ) . Solar UV Radiation: A Potential Modifiable Risk Factor for Hypertension . Journal of the American Heart Association vol. 9 , ( 5 ) Article e015627 ,
Cabrera CP, Ng FL, Nicholls HL, Gupta A, Barnes MR, Munroe PB, Caulfield MJ ( 2019 ) . Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicated . Human Molecular Genetics vol. 28 , ( R2 ) R151 - R161 .
MANIERO C, GUPTA AK, LOBO MD ( 2019 ) . Impact of the New ACC/AHA and ESC/ESH Hypertension Guidelines in the UK . European Heart Journal vol. 40 , ( 30 ) 2472 - 2475 .
Rahimi K, Canoy D, Nazarzadeh M, Salimi-Khorshidi G, Woodward M, Teo K, Davis BR, Chalmers J et al. ( 2019 ) . Investigating the stratified efficacy and safety of pharmacological blood pressure-lowering: an overall protocol for individual patient-level data meta-analyses of over 300 000 randomised participants in the new phase of the Blood Pressure Lowering Treatment Trialists’ Collaboration (BPLTTC) . BMJ Open vol. 9 , ( 5 ) e028698 - e028698 .
Poulter NR, Dolan E, Gupta AK, O’Brien E, Whitehouse A, Sever PS ( 2019 ) . Efficacy and Safety of Incremental Dosing of a New Single-Pill Formulation of Perindopril and Amlodipine in the Management of Hypertension . American Journal of Cardiovascular Drugs vol. 19 , ( 3 ) 313 - 323 .
Berkelmans GFN, Gudbjörnsdottir S, Visseren FLJ, Wild SH, Franzen S, Chalmers J, Davis BR, Poulter NR et al. ( 2019 ) . Prediction of individual life-years gained without cardiovascular events from lipid, blood pressure, glucose, and aspirin treatment based on data of more than 500 000 patients with Type 2 diabetes mellitus . European Heart Journal vol. 40 , ( 34 ) 2899 - 2906 .
Gupta AK, Sen S, Kumari R, Chakraborty DP, Kumar A ( 2019 ) . Influence of weathering on coking properties of coals used in coke making . Impc 2018 29th International Mineral Processing Congress . 124 - 130 .
Gupta A, Mackay J, Whitehouse A, Godec T, Collier T, Poulter N, Sever P ( 2018 ) . A17615 Baseline predictors of all-cause- and cardiovascular- mortality amongst 8580 hypertensive patients followed up for 16 years in the ASCOT legacy study . Journal of Hypertension . vol. 36 , e251 - e251 .
Pushpasekaran N, Gupta D, Kashyap A, Arora S, Gupta AK ( 2018 ) . Concomitant methicillin-resistant Staphylococcus aureus infection in tubercular sacroiliitis masquerading as anti-tubercular drug resistance: Role for molecular diagnosis . Indian Journal of Tuberculosis vol. 65 , ( 4 ) 350 - 355 .
Gupta A, Mackay J, Whitehouse A, Godec T, Collier T, Pocock S, Poulter N, Sever P ( 2018 ) . Long-term mortality after blood pressure-lowering and lipid-lowering treatment in patients with hypertension in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Legacy study: 16-year follow-up results of a randomised factorial trial . The Lancet vol. 392 , ( 10153 ) 1127 - 1137 .
Saxena M, Shour T, Shah M, Wolff CB, Julu POO, Kapil V, Collier DJ, Ng FL et al. ( 2018 ) . Attenuation of Splanchnic Autotransfusion Following Noninvasive Ultrasound Renal Denervation: A Novel Marker of Procedural Success . Journal of the American Heart Association vol. 7 , ( 12 ) Article e009151 ,
McGlone ER, Gupta AK, Reddy M, Khan OA ( 2018 ) . Antral resection versus antral preservation during laparoscopic sleeve gastrectomy for severe obesity: Systematic review and meta-analysis . Surgery for Obesity and Related Diseases vol. 14 , ( 6 ) 857 - 864 .
Gupta A, Mackay J, Whitehouse A, Godec T, Collier T, Poulter N, Sever P ( 2018 ) . DETERMINANTS OF LONG-TERM ALL-CAUSE AND CARDIOVASCULAR MORTALITY IN HYPERTENSIVE PATIENTS – FINDINGS FROM 16-YEAR FOLLOW-UP OF THE ASCOT LEGACY STUDY . Journal of Hypertension . vol. 36 , e27 - e27 .
Gupta AK ( 2018 ) . Hypertensive Disorders in Pregnancy and the Risk of Cardiovascular Disease: A Need for Postpartum Strategies for the Primary Prevention . Journal of the American Heart Association vol. 7 , ( 10 ) Article e009648 ,
Godec T, Mackay J, Whitehouse A, Whitehouse A, Poulter NNP, Sever P, Gupta A ( 2018 ) . The role of pulse pressure in comparison to systolic blood pressure in the prediction of long-term risk of all-cause-and cardiovascular-mortality, and the influence of age on these relationships, amongst hypertensive patients in the ASCOT-legacy study . JOURNAL OF HUMAN HYPERTENSION . vol. 32 , 695 - 696 .
Gupta A, Godec T, Sever P ( 2017 ) . Concerns related to the nocebo effect – Authors' reply . The Lancet vol. 390 , ( 10105 ) 1832 - 1832 .
Gupta AK, Poulter N, Ariti C ( 2017 ) . 5943Clinical efficacy of the combination of atorvastatin and perindopril in prevention of cardiovascular outcomes and mortality among high-risk hypertensive patients randomized to the ASCOT-LLA trial . European Heart Journal vol. 38 , ( suppl_1 )
Gupta A, Thompson D, Whitehouse A, Collier T, Dahlof B, Poulter N, Collins R, Sever P ( 2017 ) . Adverse events associated with unblinded, but not with blinded, statin therapy in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid-Lowering Arm (ASCOT-LLA): a randomised double-blind placebo-controlled trial and its non-randomised non-blind extension phase . The Lancet vol. 389 , ( 10088 ) 2473 - 2481 .
Marcano-Belisario JS, Gupta AK, O’Donoghue J, Ramchandani P, Morrison C, Car J ( 2017 ) . Implementation of depression screening in antenatal clinics through tablet computers: results of a feasibility study . BMC Medical Informatics and Decision Making vol. 17 , ( 1 ) Article 59 ,
Gupta A, Malik N, Jain S ( 2017 ) . Sustainability in competitive market through innovation and creativity-quality up-gradation and operational excellence-a case study contributing to orient's growth journey . IPPTA Quarterly Journal of Indian Pulp and Paper Technical Association vol. 29 , ( 1 ) 112 - 117 .
Gupta AK, Poulter N, Ariti C ( 2017 ) . Clinical efficacy of the combination of atorvastatin and perindopril in prevention of cardiovascular outcomes and mortality among high-risk hypertensive patients randomized to the ASCOT-LLA trial . EUROPEAN HEART JOURNAL . vol. 38 , 1254 - 1254 .
Sever P, Gupta A, Thompson D, Whitehouse A, Collier T, Dahlof B, Poulter N ( 2016 ) . LBOS 01-04 THE TRUE INCIDENCE OF STATIN -RELATED ADVERSE EVENTS IN HYPERTENSIVE PATIENTS REVEALED BY COMPARISON OF BLINDED AND UN-BLINDED USE OF STATIN IN THE ANGLO-SCANDINAVIAN CARDIAC OUTCOMES TRIAL (ASCOT) . Journal of Hypertension . vol. 34 , e547 - e548 .
Stam-Slob MC, Visseren FLJ, Wouter Jukema J, van der Graaf Y, Poulter NR, Gupta A, Sattar N, Macfarlane PW et al. ( 2016 ) . Personalized absolute benefit of statin treatment for primary or secondary prevention of vascular disease in individual elderly patients . Clinical Research in Cardiology vol. 106 , ( 1 ) 58 - 68 .
Marcano-Belisario JS, Gupta AK, O'Donoghue J, Morrison C, Car J ( 2016 ) . Tablet computers for implementing NICE antenatal mental health guidelines: protocol of a feasibility study . BMJ Open vol. 6 , ( 1 ) e009930 - e009930 .
McGlone ER, Gupta A, Maclean W, Reddy M, Khan O ( 2016 ) . Antral-preserving or antral-resecting sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis . BRITISH JOURNAL OF SURGERY . vol. 103 , 13 - 14 .
Watson S, Gupta AK, Poulter N ( 2014 ) . Influence of a short-term school-based intervention on the health behaviours and prevalence of obesity among schoolchildren and their parents: results of the RATIONAL HEALTH pilot programme . DIABETIC MEDICINE . vol. 31 , 23 - 23 .
Thom S ( 2013 ) . Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD . JAMA vol. 310 , ( 9 ) 918 - 918 .
Prieto-Merino D, Dobson J, Gupta AK, Chang C-L, Sever PS, Dahlöf B, Wedel H, Pocock S et al. ( 2013 ) . ASCORE: an up-to-date cardiovascular risk score for hypertensive patients reflecting contemporary clinical practice developed using the (ASCOT-BPLA) trial data . Journal of Human Hypertension vol. 27 , ( 8 ) 492 - 496 .
Kelishadi R, de Ferranti SD, Majdzadeh R, O’Dea JA, Gupta AK, Adeli K ( 2013 ) . Childhood Obesity: Today and Tomorrow’s Health Challenge . Journal of Obesity vol. 2013 , 1 - 2 .
Chapman N, Dixon F, Gupta AK ( 2013 ) . Incidence of angioedema in randomised controlled trials of angiotensin receptor blockers: a meta-analysis . EUROPEAN HEART JOURNAL . vol. 34 , 335 - 335 .
Kelishadi R, Amin MM, Haghdoost AA, Gupta AK, Tuhkanen TA ( 2013 ) . Pollutants Source Control and Health Effects . Journal of Environmental and Public Health vol. 2013 , 1 - 2 .
Elley CR, Gupta AK, Webster R, Selak V, Jun M, Patel A, Rodgers A, Thom S ( 2012 ) . The Efficacy and Tolerability of ‘Polypills’: Meta-Analysis of Randomised Controlled Trials . PLoS ONE vol. 7 , ( 12 ) e52145 - e52145 .
Sever PS, Chang CL, Prescott MF, Gupta A, Poulter NR, Whitehouse A, Scanlon M ( 2012 ) . Is plasma renin activity a biomarker for the prediction of renal and cardiovascular outcomes in treated hypertensive patients? Observations from the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) . European Heart Journal vol. 33 , ( 23 ) 2970 - 2979 .
Rosenthal VD, Jarvis WR, Jamulitrat S, Silva CPR, Ramachandran B, Dueñas L, Gurskis V, Ersoz G et al. ( 2012 ) . Socioeconomic impact on device-associated infections in pediatric intensive care units of 16 limited-resource countries . Pediatric Critical Care Medicine vol. 13 , ( 4 ) 399 - 406 .
Gupta A, Udupa N, Sreedhar D ( 2012 ) . Fixed-dose combinations . Pharmaceutical Technology Europe vol. 24 , ( 1 )
Gupta AK ( 2011 ) . The efficacy and cost-effectiveness of statins in low-risk patients . Canadian Medical Association Journal vol. 183 , ( 16 ) 1821 - 1823 .
Gupta AK, Nasothimiou EG, Chang CL, Sever PS, Dahlöf B, Poulter NR ( 2011 ) . Baseline predictors of resistant hypertension in the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT) . Journal of Hypertension vol. 29 , ( 10 ) 2004 - 2013 .
Sever PS, Chang CL, Gupta AK, Whitehouse A, Poulter NR ( 2011 ) . The Anglo-Scandinavian Cardiac Outcomes Trial: 11-year mortality follow-up of the lipid-lowering arm in the UK . European Heart Journal vol. 32 , ( 20 ) 2525 - 2532 .
Gupta AK, Prieto‐Merino D, Dahlöf B, Sever PS, Poulter NR ( 2011 ) . Metabolic syndrome, impaired fasting glucose and obesity, as predictors of incident diabetes in 14 120 hypertensive patients of ASCOT‐BPLA: comparison of their relative predictability using a novel approach . Diabetic Medicine vol. 28 , ( 8 ) 941 - 947 .
Gupta AK, Savopoulos CG, Ahuja J, Hatzitolios AI ( 2011 ) . Role of phytosterols in lipid-lowering: current perspectives . QJM vol. 104 , ( 4 ) 301 - 308 .
Bangalore S, Kumar S, Kjeldsen SE, Makani H, Grossman E, Wetterslev J, Gupta AK, Sever PS et al. ( 2011 ) . Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324 168 participants from randomised trials . The Lancet Oncology vol. 12 , ( 1 ) 65 - 82 .
Gupta AK, Chang CL, Dahlof B, Poulter NR, Sever PS ( 2011 ) . Cardiovascular and all-cause mortality outcomes among hypertensive patients with moderate renal dysfunction in the ASCOT-LLA, and its extended follow-up . EUROPEAN HEART JOURNAL . vol. 32 , 220 - 220 .
Gupta AK ( 2010 ) . Racial differences in response to antihypertensive therapy: Does one size fits all? . International Journal of Preventive Medicine vol. 1 , ( 4 ) 217 - 219 .
Gupta AK, Poulter NR ( 2010 ) . The Concept of the Metabolic Syndrome . vol. 56 , Elsevier BV
Gupta AK, Poulter NR, Dobson J, Eldridge S, Cappuccio FP, Caulfield M, Collier D, Cruickshank JK et al. ( 2010 ) . Ethnic Differences in Blood Pressure Response to First and Second-Line Antihypertensive Therapies in Patients Randomized in the ASCOT Trial . AM J HYPERTENS vol. 23 , ( 9 ) 1023 - 1030 .
Gupta AK, Dahlof B, Sever PS, Poulter NR ( 2010 ) . Metabolic Syndrome, Independent of Its Components, Is a Risk Factor for Stroke and Death But Not for Coronary Heart Disease Among Hypertensive Patients in the ASCOT-BPLA . Diabetes Care vol. 33 , ( 7 ) 1647 - 1651 .
Gupta AK, Arshad S, Poulter NR ( 2010 ) . Compliance, Safety, and Effectiveness of Fixed-Dose Combinations of Antihypertensive Agents . Hypertension vol. 55 , ( 2 ) 399 - 407 .
Prieto-Merino D, Gupta AK, Dobson J, Chang CL, Mastorantonakis S, Sever PS, Dahlof B, Wede H et al. ( 2009 ) . ASCORE: AN UP-TO-DATE CARDIOVASCULAR RISK SCORE FOR HYPERTENSIVE PATIENTS REFLECTING CONTEMPORARY CLINICAL PRACTICES DEVELOPED USING THE ASCOT TRIAL DATABASE . JOURNAL OF HYPERTENSION . vol. 27 , S315 - S315 .
Prieto-Merino D, Gupta AK, Dobson J, Chang CL, Mastorantonakis S, Sever PS, Dahlof B, Wedel H et al. ( 2009 ) . ASCORE: an up-to-date cardiovascular risk score for hypertensive patients reflecting contemporary clinical practices developed using the ASCOT trial database . JOURNAL OF HUMAN HYPERTENSION . vol. 23 , 695 - 695 .
Gupta AK, Poulter NR, Eldridge S, Cappuccio FP, Caulfield MJ, Dobson J, Cruickshank JK, Griffiths CJ et al. ( 2008 ) . Ethnic differences in blood pressure response to atenolol and amlodipine monotherapy and to add on diuretic and ACE inhibitor dual therapy in hypertensive patients from UK in ASCOT-BPLA . J HUM HYPERTENS vol. 22 , ( 10 ) 726 - 727 .
Gupta AK, Dahlof B, Dobson J, Sever PS, Wedel H, Poulter NR ( 2008 ) . Determinants of New-Onset Diabetes Among 19,257 Hypertensive Patients Randomized in the Anglo-Scandinavian Cardiac Outcomes Trial–Blood Pressure Lowering Arm and the Relative Influence of Antihypertensive Medication . Diabetes Care vol. 31 , ( 5 ) 982 - 988 .
Arshad S, Gupta AK, Poulter NR ( 2008 ) . Comparison of effectiveness and safety of fixed-dose combinations of antihypertensive agents with the free-drug combination of its components when given separately in hypertensive patients: a meta-analysis of 32 134 patients . JOURNAL OF HUMAN HYPERTENSION . vol. 22 , 726 - 726 .
Poulter NR, Chang CL, Dahlof B, Gupta AK, Sever PS, Wedel H ( 2008 ) . Evaluating the efficacy of the stepped-care anti-hypertensive strategies used in the Anglo-Scandinavian Cardiac Outcomes Trial BP Lowering Arm (ASCOT-BPLA) . JOURNAL OF HYPERTENSION . vol. 26 , S10 - S10 .
Gupta A, Kamineni S, Patten DK, Skourat R ( 2007 ) . Displaced Operable Radial Head Fractures . European Journal of Trauma and Emergency Surgery vol. 34 , ( 4 ) 378 - 384 .
Gupta AK, Poulter NR ( 2007 ) . Antihypertensive-Associated Incident Diabetes: Controversy Persists . vol. 167 , American Medical Association (AMA)
GUPTA A, POULTER N ( 2007 ) . Improving the Prognosis in Patients With Diabetes: What Will ADVANCE Tell Us? . American Journal of Hypertension vol. 20 , ( 7 ) S19 - S22 .
Gupta AK, Poulter NR ( 2007 ) . Antihypertensive-associated incident diabetes: controversy persists . Arch Intern Med , vol. 167 ,
Gupta AK, Poulter NR, Dahlof B, Sever P, Wedel H ( 2007 ) . Role of metabolic syndrome, independent of its components, in prediction of cardiovascular outcomes in hypertensive patients in the ASCOT-BPLA . JOURNAL OF HUMAN HYPERTENSION . vol. 21 , 836 - 837 .
Gupta AK, Poulter NR, Dahlof B, Marro JE, Sever PS, Wedel H ( 2006 ) . Determinants of new onset diabetes among hypertensive patients randomised in the ASCOT-BPLA trial . JOURNAL OF HYPERTENSION . vol. 24 , 43 - 43 .
Ahuja J, Gupta M, Gupta AK, Kohli K ( 2004 ) . Pharmacoeconomics . NATIONAL MEDICAL JOURNAL OF INDIA vol. 17 , ( 2 ) 80 - 83 .
Monga A, Makkar RPS, Arora A, Mukhopadhyay S, Gupta AK ( 2003 ) . Case report: Acute Hepatitis E Infection with Co‐Existent Glucose‐6‐Phosphate Dehydrogenase Deficiency . Canadian Journal of Infectious Diseases and Medical Microbiology vol. 14 , ( 4 ) 230 - 231 .
Monga A, Arora A, Makkar RPS, Gupta AK ( 2003 ) . Hypertriglyceridemia-induced acute pancreatitis - Treatment with heparin and insulin . Indian Journal of Gastroenterology vol. 22 , ( 3 ) 102 - 103 .
Makkar RPS, Monga A, Arora A, Mukhopadhyay S, Gupta AK ( 2003 ) . Self‐referral to specialists – a dodgy proposition . International Journal of Health Care Quality Assurance vol. 16 , ( 2 ) 87 - 89 .
Makkar RPS, Mukhopadhyay S, Monga A, Arora A, Gupta AK ( 2003 ) . Palmar erythema and hoarseness: an unusual clinical presentation of sarcoidosis . Medical Journal of Australia vol. 178 , ( 2 ) 75 - 76 .
Makkar RP, Arora A, Monga A, Gupta AK ( 2003 ) . Alport's syndrome with blue sclera . Journal of the Association of Physicians of India vol. 51 , 510 - 511 .
Makkar RPS, Arora A, Monga A, Gupta AK, Mukhopadhyay S ( 2003 ) . Burning feet syndrome. A clinical review . Australian Family Physician vol. 32 , ( 12 ) 1006 - 1009 .
Singh NP, Arora SK, Gupta A, Anuradha S, Sridhara G, Agarwal SK, Gulati P ( 2003 ) . Stroke: A rare presentation of cardiac hydatidosis . NEUROLOGY INDIA vol. 51 , ( 1 ) 120 - 121 .
Makkar RPS, Monga SMA, Gupta AK ( 2002 ) . Plasmodium vivax malaria presenting with severe thrombocytopenia . Brazilian Journal of Infectious Diseases vol. 6 , ( 5 )
Anuradha S, Agarwal SK, Singh NP, Gupta A, Chowdhury V ( 2002 ) . An unusual presentation of the Papillon-Lefevre syndrome as recurrent liver abscesses . The Journal of the Association of Physicians of India vol. 50 , 974 - 976 .
Anuradha S, Bansal R, Gupta A, Singh NP, Kohli R, Agarwal SK ( 2002 ) . Embolisation of haemodialysis catheter . The Journal of the Association of Physicians of India vol. 50 , 608 - 609 .
Monga A, Arora A, Makkar RPS, Gupta AK ( 2002 ) . A rare site for tuberculosis . CANADIAN MEDICAL ASSOCIATION JOURNAL vol. 167 , ( 10 ) 1149 - 1150 .