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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: DR Irene Pinzuti

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Benucci B, Spinello Z, Calvaresi V, Viviani V, Perrotta A, Faleri A, Pansegrau W, d’Alterio L et al. ( 2024 ) . Neisserial adhesin A (NadA) binds human Siglec-5 and Siglec-14 with high affinity and promotes bacterial adhesion/invasion . mBio vol. 15 , ( 8 ) e01107 - e01124 .
Boos J, van der Made CI, Ramakrishnan G, Coughlan E, Asselta R, Löscher B-S, Valenti LVC, de Cid R et al. ( 2024 ) . Stratified analyses refine association between TLR7 rare variants and severe COVID-19 . Human Genetics and Genomics Advances vol. 5 , ( 4 )
Kliza KW, Song W, Pinzuti I, Schaubeck S, Kunzelmann S, Kuntin D, Fornili A, Hofmann K ( 2024 ) . N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling . Cell Death Discovery vol. 10 , ( 1 )
Kanai M, Andrews SJ, Cordioli M, Stevens C, Neale BM, Daly M, Ganna A, Chwialkowska K et al. ( 2023 ) . A second update on mapping the human genetic architecture of COVID-19 . Nature vol. 621 , ( 7977 ) e7 - e26 .
Clohisey S, Millar J, Shankar-Hari M, Aitkin E, Aravindan L, Armstrong R, Baillie JK, Biggs H et al. ( 2023 ) . Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 . Nature vol. 619 , ( 7971 ) e61 - e61 .
Clohisey S, Millar J, Shankar-Hari M, Aitkin E, Aravindan L, Armstrong R, Baillie JK, Biggs H et al. ( 2023 ) . GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 . Nature vol. 617 , ( 7962 ) 764 - 768 .
Baillie JK, Begg C, Clohisey Hendry S, Hinds C, Horby P, Knight J, Ling L, Maslove D et al. ( 2022 ) . Whole-genome sequencing reveals host factors underlying critical COVID-19 . Nature vol. 607 , ( 7917 ) 97 - 103 .
Niemi MEK, Karjalainen J, Liao RG, Neale BM, Daly M, Ganna A, Davis L, Lee S et al. ( 2021 ) . Mapping the human genetic architecture of COVID-19 . Nature vol. 600 , ( 7889 ) 472 - 477 .
Green JL, Wu Y, Encheva V, Lasonder E, Prommaban A, Kunzelmann S, Christodoulou E, Grainger M et al. ( 2020 ) . Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development . PLOS Pathogens vol. 16 , ( 6 )
Burlina F, Abdel-Aal A-BM, Raz R, Pinzuti I, Papageorgiou G, Li J, Antrobus R ( 2019 ) . Auxiliary-assisted chemical ubiquitylation of NEMO and linear extension by HOIP . Communications Chemistry vol. 2 , ( 1 )
Kliza K, Taumer C, Pinzuti I, Franz-Wachtel M, Kunzelmann S, Stieglitz B, Husnjak K ( 2017 ) . Internally tagged ubiquitin: a tool to identify linear polyubiquitin-modified proteins by mass spectrometry . Nature Methods vol. 14 , ( 5 ) 504 - 512 .
Scietti L, Sampieri K, Pinzuti I, Bartolini E, Benucci B, Liguori A, Haag AF, Lo Surdo P et al. ( 2016 ) . Exploring host-pathogen interactions through genome wide protein microarray analysis . Scientific Reports vol. 6 , ( 1 )
Kliza K, Song W, Pinzuti I, Schaubeck S, Kunzelmann S, Kuntin D, Fornili A, Pandini A et al. . N4BP1 is dimerization-dependent linear ubiquitin reader regulating TNFR1 signalling through linear ubiquitin binding and Caspase-8-mediated processing .
Wu Y, Encheva V, Green JL, Lasonder E, Prommaban A, Kunzelmann S, Christodoulou E, Grainger M et al. . Protein ubiquitylation is essential for the schizont to merozoite transition in Plasmodium falciparum blood-stage development .
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