Publications: PROF Alberto Mantovani

Mantovani A, Garlanda C ( 2026 ) . Turn CAR T against TAMs . Cancer Cell

Cappadona C, Rimoldi V, Tettamanzi F, Cardamone G, Mantovani A, Soldà G, Paraboschi EM, Asselta R ( 2026 ) . Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severity . EBioMedicine vol. 123 ,

Mantovani A ( 2026 ) . The Cytokine Universe, From Lymphodrek to Bedside . Encyclopedia of Immunobiology , Elsevier

Voza A, Aliberti S, Bonelli F, Ingallinella P, Ghezzi E, Mauro C, Rossini C, Mastronardo C et al. ( 2025 ) . A machine learning model including pentraxin-3 as predictor of outcomes in community-acquired pneumonia . Journal of Translational Medicine vol. 23 , ( 1 )

Mikulak J, Supino D, Marzano P, Terzoli S, Carriero R, Cazzetta V, Piazza R, Bruni E et al. ( 2025 ) . Tissue-specific anti-tumor NK cell subsets identified in colorectal cancer liver metastases express candidate therapeutic targets . Journal of Clinical Investigation vol. 135 , ( 24 )

Boutet M-A, Mattiola I, Silva-Gomes R, Nerviani A, Sironi M, Ghirardi GM, Troilo A, Gianoli S et al. ( 2025 ) . Synovial MS4A4A correlates with inflammation and counteracts response to corticosteroids in arthritis . Proceedings of the National Academy of Sciences of the United States of America vol. 122 , ( 37 )

Giovanardi G, Liberati FR, Noemi M, Barbara B, Albani E, Mantovani A, Luciano AM, Asselta R et al. ( 2025 ) . P-197 The long pentraxin PTX3 as cumulus oophorous extracellular matrix marker of follicular development, oocyte maturity, and embryo quality in human assisted reproduction . Human Reproduction vol. 40 , ( Supplement_1 )

Belgiovine C, Digifico E, Erreni M, Putignano AR, Mannarino L, Valentino S, Grizzi F, Pasqualini F et al. ( 2025 ) . Malignant mesothelioma-associated inflammatory microenvironment promotes tumor progression via GPNMB . Journal of Translational Medicine vol. 23 , ( 1 )

Supino D, Davoudian S, Silva-Gomes R, Piovani D, Garuti R, Desai A, Mapelli SN, Scavello F et al. ( 2025 ) . Monocyte-macrophage membrane expression of IL-1R2 is a severity biomarker in sepsis . Cell Death & Disease vol. 16 , ( 1 )

Conforti F, Pala L, Di Mitri D, Catania C, Cocorocchio E, Laszlo D, Ceresoli G, Locatelli M et al. ( 2025 ) . Sex hormones, the anticancer immune response, and therapeutic opportunities . Cancer Cell vol. 43 , ( 3 ) 343 - 360 .

Albano F, Poeta VM, Zotti L, Castagna A, Felicetta A, Mesaglio A, Sironi M, Di Donato R et al. ( 2025 ) . Selective expression and significance of ACKR2 in lung aerocytes . Journal for ImmunoTherapy of Cancer vol. 13 , ( 1 )

Shah A, Zhang X, Snee M, Lockhart-Cairns MP, Levy CW, Jowitt TA, Birchenough HL, Dean L et al. ( 2025 ) . The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix . Matrix Biology vol. 136 , 52 - 68 .

Mantovani A ( 2025 ) . The Cytokine Universe, From Lymphodrek to Bedside . Encyclopedia of Immunobiology ,

Laurent P-A, André F, Bobard A, Deandreis D, Depil S, Eichmüller SB, Fernandez-Palomo C, Foijer F et al. ( 2024 ) . Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7th immunorad conference . OncoImmunology vol. 14 , ( 1 ) 2432726 - 2432726 .

Laffranchi M, Paraboschi EM, Bianchetto-Aguilera F, Tamassia N, Gardiman E, Piserà A, Del Prete A, Invernizzi P et al. ( 2024 ) . Neutrophils restricted contribution of CCRL2 genetic variants to COVID-19 severity . Heliyon vol. 11 , ( 1 )

Granata V, Strina D, Possetti V, Valentino S, Chiappetta K, Bottazzi B, Mantovani A, Loppini M et al. ( 2024 ) . POLYMORPHISMS IN THE IL-1Β AND IL-10 GENES AFFECT THE RISK OF PERIPROSTHETIC JOINT INFECTION IN TOTAL HIP AND KNEE ARTHROPLASTY PATIENTS . Orthopaedic Proceedings vol. 106-B , ( SUPP_19 ) 32 - 32 .

Doni A, Sironi M, Del Prete A, Pasqualini F, Valentino S, Parente R, Calvi M, Vago G et al. ( 2024 ) . PTX3 is expressed in terminal lymphatics and shapes their organization and function . Frontiers in Immunology vol. 15 ,

Allavena P, Bianchi G, Paganin C, Martin Padura I, Bottazzi B, Drogari MA, Gaboli M, Mantovani A ( 2024 ) . Interaction of Human Natural Killer Cells with the Vascular Endothelium: Characterization of their Migratory Ability and Adhesive Molecules . Nk Cell Mediated Cytotoxicity , Taylor & Francis

Erreni M, Fumagalli MR, D’Anna R, Sollai M, Bozzarelli S, Nappo G, Parente R, Garlanda C et al. ( 2024 ) . Depicting the cellular complexity of pancreatic adenocarcinoma by Imaging Mass Cytometry: focus on cancer-associated fibroblasts . Frontiers in Immunology vol. 15 ,

Mantovani A, Marchesi F, Garlanda C ( 2024 ) . Macrophage diversity in cancer dissemination and metastasis . Cellular & Molecular Immunology vol. 21 , ( 11 ) 1201 - 1214 .

Kerneur C, Foucher E, Guillén Casas J, Colazet M, Le K-S, Fullana M, Bergot E, Audemard C et al. ( 2024 ) . BTN2A1 targeting reprograms M2-like macrophages and TAMs via SYK and MAPK signaling . Cell Reports vol. 43 , ( 10 )

Scavello F, Brunetta E, Mapelli SN, Nappi E, Martín IDG, Sironi M, Leone R, Solano S et al. ( 2024 ) . The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19 . EBioMedicine vol. 108 , 105372 - 105372 .

Scavello F, Brunetta E, Mapelli SN, Nappi E, García Martín ID, Sironi M, Leone R, Solano S et al. ( 2024 ) . The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19 . EBioMedicine vol. 105 ,

Pala L, Pagan E, Sala I, Oriecuia C, Oliari M, De Pas T, Specchia C, Cocorocchio E et al. ( 2024 ) . Outcomes of patients with advanced solid tumors who discontinued immune-checkpoint inhibitors: a systematic review and meta-analysis . EClinicalMedicine vol. 73 ,

Shi Y, Strasser A, Green DR, Latz E, Mantovani A ( 2024 ) . Legacy of the discovery of the T-cell receptor: 40 years of shaping basic immunology and translational work to develop novel therapies . Cellular & Molecular Immunology vol. 21 , ( 7 ) 790 - 797 .

Granata V, Strina D, Possetti V, Leone R, Valentino S, Chiappetta K, Loppini M, Sobacchi C ( 2024 ) . Interleukin-1β Polymorphisms Are Genetic Markers of Susceptibility to Periprosthetic Joint Infection in Total Hip and Knee Arthroplasty . Genes vol. 15 , ( 5 )

Andon FT, Pensado-López A, Anfray C, Ummarino A, Fernández-Mariño I, Sanjurjo L, Crecente-Campo J, Fernández-Megía E et al. ( 2024 ) . Abstract 715: Nanomedicines loaded with TLR agonists and inhibitors of immunosuppression to reprogram the tumor microenvironment . Cancer Research vol. 84 , ( 6_Supplement ) 715 - 715 .

Carnevale S, Ponzetta A, Rigatelli A, Carriero R, Puccio S, Supino D, Grieco G, Molisso P et al. ( 2024 ) . Neutrophils mediate protection against colitis and carcinogenesis by controlling bacterial invasion and IL-22 production by γδ T cells . Cancer Immunology Research vol. 12 , ( 4 ) 413 - 426 .

Rigamonti A, Viatore M, Polidori R, Rahal D, Erreni M, Fumagalli MR, Zanini D, Doni A et al. ( 2024 ) . Integrating AI-powered digital pathology and imaging mass cytometry identifies key classifiers of tumor cells, stroma, and immune cells in non-small cell lung cancer . Cancer Research vol. 84 , ( 7 ) 1165 - 1177 .

Mantovani A, Colotta F, Sozzani S ( 2024 ) . Chemokines in Vascular Pathophysiology . Immune Functions of the Vessel Wall ,

Di Mitri D, Mantovani A, Marchesi F ( 2024 ) . Phenotypic and functional diversity of tumor-associated macrophages . Reference Module in Biomedical Sciences , Elsevier

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Durjava M, Dusemund B, Kouba M et al. ( 2023 ) . Guidance on the assessment of the safety of feed additives for the users . EFSA Journal vol. 21 , ( 12 )

Parente R, Possetti V, Granata V, Schiavone ML, Strina D, Davi F, Menale C, Palagano E et al. ( 2023 ) . EMERGING ROLES OF THE LONG PENTRAXIN PTX3 IN STAPHYLOCOCCUS AUREUS-DEPENDENT OSTEOMYELITIS . Orthopaedic Proceedings vol. 105-B , ( SUPP_17 ) 25 - 25 .

Granata V, Strina D, Bottazzi B, Mantovani A ( 2023 ) . Genetic Deficiency of the Long Pentraxin 3 Affects Osteogenesis and Osteoclastogenesis in Homeostatic and Inflammatory Conditions . International Journal of Molecular Sciences vol. 24 , ( 23 )

Mantovani A, Dinarello CA, Ghezzi P ( 2023 ) . Pharmacology of cytokines . Oxford University Press (OUP)

Meri S, Mantovani A, Garlanda C ( 2023 ) . The Yin Yang of Complement and Cancer . Cancer Immunology Research vol. 11 , ( 12 ) 1578 - 1588 .

Kanai M, Andrews SJ, Cordioli M, Stevens C, Neale BM, Daly M, Ganna A, Chwialkowska K et al. ( 2023 ) . A second update on mapping the human genetic architecture of COVID-19 . Nature vol. 621 , ( 7977 ) e7 - e26 .

Garlanda C, Stravalaci M, Pagani I, Paraboschi EM, Scavello F, Asselta R, Vicenzi E, Mantovani A ( 2023 ) . 29 Humoral innate immunity and acute phase proteins in COVID-19 . Immunobiology vol. 228 , ( 5 )

Stravalaci M, Pagani I, Zhong H, Sironi M, Bondesan S, Barzaghi F, Carrera P, Izzo F et al. ( 2023 ) . 115 The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2 . Immunobiology vol. 228 , ( 5 ) 152566 - 152566 .

Shiffer D, Zamunér AR, Minonzio M, Bulgheroni M, Porta A, Leone R, Bottazzi B, Garlanda C et al. ( 2023 ) . Soluble interleukin-1 receptor type 2 plasma levels in Parkinson’s disease: relationship with cardiac autonomic profile before and after peripheral mechanical somatosensory stimulation . Frontiers in Physiology vol. 14 ,

Pozzi C, Sarti R, Levi R, Mollura M, Azzolini E, Barbieri R ( 2023 ) . Association Between Duration of SARS-CoV-2 Positivity and Long COVID . Clinical Infectious Diseases vol. 77 , ( 11 ) 1531 - 1533 .

Logroscino G, Fidanza A, Giusti I, Poppa G, Troianello L, Calafiore F, Saracco M, Mantovani A ( 2023 ) . Pentraxin 3, a new biomarker for the diagnosis and management of PJI in primary and revision hip arthroplasty . Acta BioMedica vol. 94 , ( S2 )

Sozio F, Schioppa T, Laffranchi M, Salvi V, Tamassia N, Bianchetto-Aguilera FM, Tiberio L, Bonecchi R et al. ( 2023 ) . CCRL2 Expression by Specialized Lung Capillary Endothelial Cells Controls NK-cell Homing in Lung Cancer . Cancer Immunology Research vol. 11 , ( 9 ) 1280 - 1295 .

Porte R, Silva-Gomes R, Theroude C, Parente R, Asgari F, Sironi M, Pasqualini F, Valentino S et al. ( 2023 ) . Regulation of inflammation and protection against invasive pneumococcal infection by the long pentraxin PTX3 . eLife vol. 12 ,

Pradeu T, Daignan‐Fornier B, Ewald A, Germain P, Okasha S, Plutynski A, Benzekry S, Bertolaso M et al. ( 2023 ) . Reuniting philosophy and science to advance cancer research . Biological Reviews vol. 98 , ( 5 ) 1668 - 1686 .

Costa G, Sposito C, Soldani C, Polidoro MA, Franceschini B, Nasir FD, Virdis M, Vingiani A et al. ( 2023 ) . Macrophage morphology and distribution are strong predictors of prognosis in resected colorectal liver metastases: results from an external retrospective observational study . International Journal of Surgery vol. 109 , ( 5 ) 1311 - 1317 .

Ummarino A, Anfray C, Mariancini A, Supino D, Garlanda C, Andòn FT, Mantovani A, Allavena P ( 2023 ) . Abstract 5140: Combined administration of poly(I:C) and resiquimod triggers effective antitumoral response in mouse models of pancreatic adenocarcinoma . Cancer Research vol. 83 , ( 7_Supplement ) 5140 - 5140 .

Rigamonti A, Viatore M, Polidori R, Erreni M, Fumagalli M, Rahal D, Locati M, Mantovani A et al. ( 2023 ) . Abstract 5783: Integration of AI-powered digital pathology and imaging mass cytometry to identify relevant features of the tumor microenvironment . Cancer Research vol. 83 , ( 7_Supplement ) 5783 - 5783 .

Chiari D, Pirali B, Leone R, Mantovani A ( 2023 ) . The crossroad between autoimmune disorder, tissue remodeling and cancer of the thyroid: The long pentraxin 3 (PTX3) . Frontiers in Endocrinology vol. 14 ,

Muri J, Cecchinato V, Cavalli A, Shanbhag AA, Matkovic M, Biggiogero M, Maida PA, Moritz J et al. ( 2023 ) . Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course . Nature Immunology vol. 24 , ( 4 ) 604 - 611 .

Di Mitri D, Conforti F ( 2023 ) . Macrophages and bone metastasis . Journal of Experimental Medicine vol. 220 , ( 4 ) e20222188 - e20222188 .

Azzolini E, Mollura M, Pozzi C, Ubaldi L, Mantovani A, Selmi C, Barbieri R, Rescigno M ( 2023 ) . Adverse Events to Comirnaty Vaccine Are Linked to Sex, Age and BMI: Should We Consider Reducing the Dose for Females? . Vaccines vol. 11 , ( 3 )

Biondi M, Tettamanti S, Galimberti S, Cerina B, Piazza R, Donsante S, Bido S, Broccoli V et al. ( 2023 ) . Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the Acute Myeloid Leukemia burden . Blood vol. 141 , ( 21 ) 2587 - 2598 .

Mariotti FR, Supino D, Landolina N, Moretta L ( 2023 ) . IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC . Seminars in Immunology vol. 66 ,

Mantovani A, Garlanda C ( 2023 ) . Humoral Innate Immunity and Acute-Phase Proteins . New England Journal of Medicine vol. 388 , ( 5 ) 439 - 452 .

Loppini M, Di Maio M, Avigni R, Leone R, Inforzato A, Mantovani A ( 2023 ) . Long Pentraxin 3 as a New Biomarker for Diagnosis of Hip and Knee Periprosthetic Joint Infections . Journal of Clinical Medicine vol. 12 , ( 3 )

Rescigno M, Agrati C, Salvarani C, Giannarelli D, Costantini M, Mantovani A, Massafra R, Zinzani PL et al. ( 2023 ) . Neutralizing antibodies to Omicron after the fourth SARS-CoV-2 mRNA vaccine dose in immunocompromised patients highlight the need of additional boosters . Frontiers in Immunology vol. 14 ,

Cortese N, Carriero R, Barbagallo M, Putignano AR, Costa G, Giavazzi F, Grizzi F, Pasqualini F et al. ( 2023 ) . High-resolution analysis of mononuclear phagocytes reveals GPNMB as a prognostic marker in human colorectal liver metastasis . Cancer Immunology Research vol. 11 , ( 4 ) 405 - 420 .

Mantovani A, Rescigno M, Forni G, Tognon F ( 2023 ) . COVID-19 vaccines and a perspective on Africa . Trends in Immunology vol. 44 , ( 3 ) 172 - 187 .

Erreni M, D'Autilia F, Avigni R, Bolli E, Arnouk SM, Movahedi K, Debie P, Anselmo A et al. ( 2023 ) . Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting . Theranostics vol. 13 , ( 1 ) 355 - 373 .

Mollura M, Sarti R, Levi R, Pozzi C, Politi LS, Mantovani A ( 2022 ) . Antibody Titer Correlates with Omicron Infection in Vaccinated Healthcare Workers . Viruses vol. 14 , ( 12 )

Gonçales RA, Bastos HN, Duarte-Oliveira C, Antunes D, Sokhatska O, Jacob M, Rolo R, Campos CF et al. ( 2022 ) . Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis . American Journal of Respiratory and Critical Care Medicine vol. 206 , ( 9 ) 1140 - 1152 .

Lapadula G, Leone R, Bernasconi DP, Biondi A, Rossi E, Bottazzi B, Bettini LR, Beretta I et al. ( 2022 ) . Long pentraxin 3 (PTX3) levels predict death, intubation and thrombotic events among hospitalized patients with COVID-19 . Frontiers in Immunology vol. 13 ,

Grasselli G, Zanella A, Carlesso E, Florio G, Canakoglu A, Bellani G, Bottino N, Cabrini L et al. ( 2022 ) . Association of COVID-19 Vaccinations With Intensive Care Unit Admissions and Outcome of Critically Ill Patients With COVID-19 Pneumonia in Lombardy, Italy . JAMA Network Open vol. 5 , ( 10 ) e2238871 - e2238871 .

Monnier M, Paolini L, Vinatier E, Mantovani A, Delneste Y ( 2022 ) . Antitumor strategies targeting macrophages: the importance of considering the differences in differentiation/polarization processes between human and mouse macrophages . Journal for ImmunoTherapy of Cancer vol. 10 , ( 10 )

Di Cosimo S, Lupo-Stanghellini MT, Costantini M, Mantegazza R, Ciceri F, Zinzani PL, Mantovani A, Uccelli A et al. ( 2022 ) . Safety of third dose of COVID-19 vaccination in frail patients: Results from the prospective Italian VAX4FRAIL study . Frontiers in Oncology vol. 12 ,

Davoudian S, Piovani D, Desai A, Mapelli SN, Leone R, Sironi M, Valentino S, Stravalaci M et al. ( 2022 ) . A cytokine/PTX3 prognostic index as a predictor of mortality in sepsis . Frontiers in Immunology vol. 13 ,

Mantovani A, Morrone MC, Patrono C, Santoro MG, Schiaffino S ( 2022 ) . Long Covid: where we stand and challenges ahead . Cell Death & Differentiation vol. 29 , ( 10 ) 1891 - 1900 .

Azzolini E, Levi R, Sarti R, Mantovani A ( 2022 ) . Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers . JAMA vol. 328 , ( 7 ) 676 - 678 .

Mantovani A, Allavena P, Marchesi F ( 2022 ) . Macrophages as tools and targets in cancer therapy . Nature Reviews Drug Discovery vol. 21 , ( 11 ) 799 - 820 .

Bruni E, Cimino MM, Donadon M, Carriero R, Terzoli S, Piazza R, Ravens S, Prinz I et al. ( 2022 ) . Intrahepatic CD69+Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression . Journal for ImmunoTherapy of Cancer vol. 10 , ( 7 )

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Durjava MF, Kouba M et al. ( 2022 ) . Safety and efficacy of a feed additive consisting of tocopheryl phosphate mixture (TPM) for all animal species (Avecho biotechnology limited) . EFSA Journal vol. 20 , ( 7 )

Nour J, Moregola A, Molgora M, Mantovani A, Uboldi P, Garlanda C, Norata GD ( 2022 ) . Interleukin 1 Receptor 8 Deficiency Does not Impact Atherosclerosis . Thrombosis and Haemostasis vol. 122 , ( 10 ) 1833 - 1836 .

Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H et al. ( 2022 ) . Detailed stratified GWAS analysis for severe COVID-19 in four European populations . Human Molecular Genetics vol. 31 , ( 23 ) 3945 - 3966 .

Corradini P, Agrati C, Apolone G, Mantovani A, Giannarelli D, Marasco V, Bordoni V, Sacchi A et al. ( 2022 ) . Humoral and T-Cell Immune Response After 3 Doses of Messenger RNA Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines in Fragile Patients: The Italian VAX4FRAIL Study . Clinical Infectious Diseases vol. 76 , ( 3 ) e426 - e438 .

Pala L, De Pas T, Catania C, Giaccone G, Mantovani A, Minucci S, Conforti F ( 2022 ) . Sex and cancer immunotherapy: Current understanding and challenges . Cancer Cell vol. 40 , ( 7 ) 695 - 700 .

Kamal MA, Siddiqui I, Belgiovine C, Barbagallo M, Paleari V, Pistillo D, Chiabrando C, Schiarea S et al. ( 2022 ) . Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer . Cancers vol. 14 , ( 11 )

Asselta R, Paraboschi EM, Stravalaci M, Invernizzi P, Bonfanti P, Biondi A, Pagani I, Pedotti M et al. ( 2022 ) . Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19 . Nature Immunology vol. 23 , ( 6 ) 865 - 867 .

Mantovani A, Marchesi F ( 2022 ) . A topology perspective on macrophages in melanoma metastasis . Cell Reports Medicine vol. 3 , ( 5 ) 100643 - 100643 .

Li Q, Wang Y, Sun Q, Knopf J, Herrmann M, Lin L, Jiang J, Shao C et al. ( 2022 ) . Immune response in COVID-19: what is next? . Cell Death & Differentiation vol. 29 , ( 6 ) 1107 - 1122 .

Darwich A, Pozzi C, Fornasa G, Lizier M, Azzolini E, Spadoni I, Carli F, Voza A et al. ( 2022 ) . BNT162b2 vaccine induces antibody release in saliva: a possible role for mucosal viral protection? . EMBO Molecular Medicine vol. 14 , ( 5 )

Cavalleri T, Greco L, Rubbino F, Hamada T, Quaranta M, Grizzi F, Craviotto V, Bossi P et al. ( 2022 ) . Tumor‐associated macrophages and risk of recurrence in stage III colorectal cancer . The Journal of Pathology Clinical Research vol. 8 , ( 4 ) 307 - 312 .

Lupo-Stanghellini MT, Di Cosimo S, Costantini M, Monti S, Mantegazza R, Mantovani A, Salvarani C, Inglese M et al. ( 2022 ) . mRNA-COVID19 Vaccination Can Be Considered Safe and Tolerable for Frail Patients . Frontiers in Oncology vol. 12 ,

Landolina N, Mariotti FR, Ingegnere T, Alicata C, Pelosi A, Veneziani I, Azzarone BG, Garlanda C et al. ( 2022 ) . IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells . Journal for ImmunoTherapy of Cancer vol. 10 , ( 3 )

Azzolini E, Canziani LM, Voza A, Mantovani A, Desai A, Pepys J, De Santis M, Ceribelli A et al. ( 2022 ) . Short-Term Adverse Events and Antibody Response to the BNT162b2 SARS-CoV-2 Vaccine in 4156 Health Care Professionals . Vaccines vol. 10 ,

Azzolini E, Pozzi C, Germagnoli L, Oresta B, Carriglio N, Calleri M, De Santis M, Finazzi S et al. ( 2022 ) . mRNA COVID-19 vaccine booster fosters B- and T-cell responses in immunocompromised patients . Life Science Alliance vol. 5 , ( 6 )

Pozzi C, Levi R, Braga D, Carli F, Darwich A, Spadoni I, Oresta B, Dioguardi CC et al. ( 2022 ) . A ‘Multiomic’ Approach of Saliva Metabolomics, Microbiota, and Serum Biomarkers to Assess the Need of Hospitalization in Coronavirus Disease 2019 . Gastro Hep Advances vol. 1 , ( 2 ) 194 - 209 .

Stravalaci M, Pagani I, Paraboschi EM, Pedotti M, Doni A, Scavello F, Mapelli SN, Sironi M et al. ( 2022 ) . Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules . Nature Immunology vol. 23 , ( 2 ) 275 - 286 .

Bonecchi R, Mantovani A ( 2022 ) . Chemokines as Regulators of Neutrophils: Focus on Tumors, Therapeutic Targeting, and Immunotherapy . Cancers vol. 14 , ( 3 )

Stravalaci M, Ferrara M, Pathak V, Davi F, Bottazzi B ( 2022 ) . The Long Pentraxin PTX3 as a New Biomarker and Pharmacological Target in Age-Related Macular Degeneration and Diabetic Retinopathy . Frontiers in Pharmacology vol. 12 ,

Parente R, Possetti V, Stravalaci M, Sironi M, Valentino S, Day A, Bottazzi B, Cunha C et al. ( 2022 ) . The alternative pathway of complement and long pentraxin PTX3 form a functional axis in the immune response to <i>Aspergillus fumigatus</i> . MOLECULAR IMMUNOLOGY . vol. 141 , 221 - 222 .

Giannoudaki E, Stefanska AM, Lawler H, Leon G, Hernandez Santana YE, Hassan N, Russell SE, Horan R et al. ( 2021 ) . Correction: SIGIRR Negatively Regulates IL-36–Driven Psoriasiform Inflammation and Neutrophil Infiltration in the Skin . The Journal of Immunology vol. 207 , ( 11 )

Parente R, Possetti V, Erreni M, D’Autilia F, Bottazzi B, Garlanda C, Mantovani A, Inforzato A et al. ( 2021 ) . Complementary Roles of Short and Long Pentraxins in the Complement-Mediated Immune Response to Aspergillus fumigatus Infections . Frontiers in Immunology vol. 12 ,

Motta JM, Rumjanek VM, Mantovani A, Locati M ( 2021 ) . Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation . Biomedicines vol. 9 , ( 10 )

Salvi V, Nguyen HO, Sozio F, Schioppa T, Gaudenzi C, Laffranchi M, Scapini P, Passari M et al. ( 2021 ) . SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8 . JCI Insight vol. 6 , ( 18 )

Corrao G, Alquati G, Apolone G, Ardizzoni A, Buzzetti G, Canonica GW, Conte P, Crovato E et al. ( 2021 ) . Real-world data: how they can help to improve quality of care . Global & Regional Health Technology Assessment vol. 8 , 134 - 139 .

Levi R, Ubaldi L, Pozzi C, Angelotti G, Sandri MT, Azzolini E, Salvatici M, Savevski V et al. ( 2021 ) . The antibody response to SARS-CoV-2 infection persists over at least 8 months in symptomatic patients . Communications Medicine vol. 1 , ( 1 )

Anfray C, Mainini F, Digifico E, Maeda A, Sironi M, Erreni M, Anselmo A, Ummarino A et al. ( 2021 ) . Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity . Journal for ImmunoTherapy of Cancer vol. 9 , ( 9 )

Agrati C, Di Cosimo S, Fenoglio D, Apolone G, Ciceri F, Ciliberto G, Baldanti F, Costantini M et al. ( 2021 ) . COVID-19 Vaccination in Fragile Patients: Current Evidence and an Harmonized Transdisease Trial . Frontiers in Immunology vol. 12 ,

Mattiola I, Mantovani A ( 2021 ) . The tetraspan MS4A family in homeostasis, immunity, and disease . Trends in Immunology vol. 42 , ( 9 ) 764 - 781 .

Silva‐Gomes R, Mapelli SN, Boutet M, Mattiola I, Sironi M, Grizzi F, Colombo F, Supino D et al. ( 2021 ) . Differential expression and regulation of MS4A family members in myeloid cells in physiological and pathological conditions . Journal of Leukocyte Biology vol. 111 , ( 4 ) 817 - 836 .

Mantovani A, Barajon I, Di Mitri D ( 2021 ) . The Innate Immune System: Macrophages and Neutrophils . Cancer Immunotherapy Principles and Practice , Springer Publishing Company

Maio M, Lahn M, Di Giacomo AM, Covre A, Calabrò L, Ibrahim R, Fox B ( 2021 ) . A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation . Journal of Experimental & Clinical Cancer Research vol. 40 , ( 1 )

Giannoudaki E, Stefanska AM, Lawler H, Leon G, Hernandez Santana YE, Hassan N, Russell SE, Horan R et al. ( 2021 ) . SIGIRR Negatively Regulates IL-36-Driven Psoriasiform Inflammation and Neutrophil Infiltration in the Skin . The Journal of Immunology vol. 207 , ( 2 ) 651 - 660 .

Niemi MEK, Karjalainen J, Liao RG, Neale BM, Daly M, Ganna A, Davis L, Lee S et al. ( 2021 ) . Mapping the human genetic architecture of COVID-19 . Nature vol. 600 , ( 7889 ) 472 - 477 .

Parente R, Possetti V, Schiavone ML, Campodoni E, Menale C, Loppini M, Doni A, Bottazzi B et al. ( 2021 ) . 3D Cocultures of Osteoblasts and Staphylococcus aureus on Biomimetic Bone Scaffolds as a Tool to Investigate the Host–Pathogen Interface in Osteomyelitis . Pathogens vol. 10 , ( 7 )

Cancian P, Cortese N, Donadon M, Di Maio M, Soldani C, Marchesi F, Savevski V, Santambrogio MD et al. ( 2021 ) . Development of a Deep-Learning Pipeline to Recognize and Characterize Macrophages in Colo-Rectal Liver Metastasis . Cancers vol. 13 , ( 13 )

Goulart MR, Watt J, Siddiqui I, Lawlor RT, Imrali A, Hughes C, Saad A, ChinAleong J et al. ( 2021 ) . Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma . npj Precision Oncology vol. 5 , ( 1 )

Gritti G, Raimondi F, Bottazzi B, Ripamonti D, Riva I, Landi F, Alborghetti L, Frigeni M et al. ( 2021 ) . Correction: Siltuximab downregulates interleukin-8 and pentraxin 3 to improve ventilatory status and survival in severe COVID-19 . Leukemia vol. 35 , ( 9 ) 2734 - 2734 .

Boutet M-A, Nerviani A, Lliso-Ribera G, Leone R, Sironi M, Hands R, Rivellese F, Del Prete A et al. ( 2021 ) . Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response . Frontiers in Immunology vol. 12 ,

Doni A, Mantovani A, Bottazzi B, Russo RC ( 2021 ) . PTX3 Regulation of Inflammation, Hemostatic Response, Tissue Repair, and Resolution of Fibrosis Favors a Role in Limiting Idiopathic Pulmonary Fibrosis . Frontiers in Immunology vol. 12 ,

Doni A, Parente R, Laface I, Magrini E, Cunha C, Colombo FS, Lacerda JF, Campos A et al. ( 2021 ) . Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus . Nature Communications vol. 12 , ( 1 )

Levi R, Azzolini E, Pozzi C, Ubaldi L, Lagioia M, Mantovani A, Rescigno M ( 2021 ) . One dose of SARS-CoV-2 vaccine exponentially increases antibodies in recovered individuals with symptomatic COVID-19 . Journal of Clinical Investigation vol. 131 , ( 12 )

Sandri MT, Azzolini E, Torri V, Carloni S, Pozzi C, Salvatici M, Tedeschi M, Castoldi M et al. ( 2021 ) . SARS-CoV-2 serology in 4000 health care and administrative staff across seven sites in Lombardy, Italy . Scientific Reports vol. 11 , ( 1 )

Frieman M, Harris AD, Herati RS, Krammer F, Mantovani A, Rescigno M, Sajadi MM, Simon V ( 2021 ) . SARS-CoV-2 vaccines for all but a single dose for COVID-19 survivors . EBioMedicine vol. 68 ,

Gritti G, Raimondi F, Bottazzi B, Ripamonti D, Riva I, Landi F, Alborghetti L, Frigeni M et al. ( 2021 ) . Siltuximab downregulates interleukin-8 and pentraxin 3 to improve ventilatory status and survival in severe COVID-19 . Leukemia vol. 35 , ( 9 ) 2710 - 2714 .

Conforti F, Pala L, Pagan E, Bagnardi V, De Pas T, Queirolo P, Pennacchioli E, Catania C et al. ( 2021 ) . Sex-Based Dimorphism of Anticancer Immune Response and Molecular Mechanisms of Immune Evasion . Clinical Cancer Research vol. 27 , ( 15 ) 4311 - 4324 .

Asgari F, Supino D, Parente R, Polentarutti N, Stravalaci M, Porte R, Pasqualini F, Barbagallo M et al. ( 2021 ) . The Long Pentraxin PTX3 Controls Klebsiella Pneumoniae Severe Infection . Frontiers in Immunology vol. 12 ,

Garlanda C ( 2021 ) . Interleukin-1 in tumor progression, therapy, and prevention . Cancer Cell vol. 39 , ( 8 ) 1023 - 1027 .

Protti A, Meessen J, Bottazzi B, Garlanda C, Milani A, Bacci M, Mantovani A, Cecconi M et al. ( 2021 ) . Circulating pentraxin 3 in severe COVID‐19 or other pulmonary sepsis . European Journal of Clinical Investigation vol. 51 , ( 5 )

Dander E, Fallati A, Gulić T, Pagni F, Gaspari S, Silvestri D, Cricrì G, Bedini G et al. ( 2021 ) . Monocyte–macrophage polarization and recruitment pathways in the tumour microenvironment of B‐cell acute lymphoblastic leukaemia . British Journal of Haematology vol. 193 , ( 6 ) 1157 - 1171 .

Corbetta L, Fabbri LM, Cavalieri D, Bonanni P, Mantovani A, Thompson B, Luo F ( 2021 ) . Stand on the Same Side Against Covid – 19: Scientific Evidence on Vaccine for Covid-19 . Substantia1233 - 1233 .

Magrini E, Di Marco S, Mapelli SN, Perucchini C, Pasqualini F, Donato A, Guevara Lopez MDLL, Carriero R et al. ( 2021 ) . Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression . Nature Cancer vol. 2 , ( 2 ) 218 - 232 .

De Santis M, Voza A, Savevski V, Badalamenti S, Cecconi M, Mantovani A, Selmi C ( 2021 ) . Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study‘ . Annals of the Rheumatic Diseases vol. 82 , ( 5 )

De Santis F, Fucà G, Schadendorf D, Mantovani A, Magnani L, Lisanti M, Pettitt S, Bellone M et al. ( 2021 ) . Anticancer innovative therapy congress: Highlights from the 10th anniversary edition . Cytokine & Growth Factor Reviews vol. 59 , 1 - 8 .

Forni G, Mantovani A ( 2021 ) . COVID-19 vaccines: where we stand and challenges ahead . Cell Death & Differentiation vol. 28 , ( 2 ) 626 - 639 .

Mantovani A, Marchesi F, Jaillon S, Garlanda C, Allavena P ( 2021 ) . Tumor-associated myeloid cells: diversity and therapeutic targeting . Cellular & Molecular Immunology vol. 18 , ( 3 ) 566 - 578 .

Silva-Gomes R, Mapelli SN, Boutet M-A, Mattiola I, Sironi M, Grizzi F, Colombo F, Supino D et al. ( 2021 ) . Expression and regulation of MS4A molecules in myeloid cells . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 166 - 167 .

Supino D, Mariancini A, Perucchini C, Carnevale S, Ponzetta A, Carriero R, Colombo F, Magrini E et al. ( 2021 ) . IL-1R8 acts as an immune checkpoint in CD8+T cells . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 95 - 95 .

Donadon M, Marchesi F, Di Tommaso L, Soldani C, Cortese N, Franceschini B, Carriero R, Mantovani A et al. ( 2021 ) . Morphology of Tumor-Associated Macrophages Dictates the Prognosis of Patients with Colorectal Liver Metastases . Hepato Pancreato Biliary . vol. 23 ,

Carnevale S, Ponzetta A, Rigatelli A, Carriero R, Supino D, Puccio S, Pasqualini F, Mariancini A et al. ( 2021 ) . Neutrophils controlling the intestinal microbiota provide protection against colitis and colitis-associated colorectal cancer . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 111 - 111 .

Boutet MA, Nerviani A, Ribera GL, Leone R, Sironi M, Hands R, Rivellese F, Del Prete A et al. ( 2021 ) . Pentraxin-3 (PTX3) circulating and synovial expression levels correlate with rheumatoid arthritis severity and tissue infiltration independently of the response to conventional treatments . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 66 - 66 .

Santana YEH, Leon G, Giannoudaki E, St Leger D, Stefanska AM, Lawler H, Mantovani A, Garlanda C et al. ( 2021 ) . Regulation of IL-36 receptor driven skin in inflammation in psoriasis . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 89 - 89 .

Salvi V, Oanh HN, Sozio F, Schioppa T, Laffranchi M, Scapini P, Passari S, Barbazz I et al. ( 2021 ) . SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8 . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 293 - 293 .

Parente R, Possetti V, Petroni F, Stravalaci M, Sironi M, Valentino S, Day AJ, Bottazzi B et al. ( 2021 ) . The alternative pathway of complement and long pentraxin PTX3 form a functional axis in the immune response to <i>Aspergillus fumigatus</i> . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 105 - 105 .

Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS et al. ( 2020 ) . Author Correction: A guiding map for inflammation . Nature Immunology vol. 22 , ( 2 ) 254 - 254 .

Stravalaci M, Davi F, Parente R, Gobbi M, Bottazzi B, Mantovani A, Day AJ, Clark SJ et al. ( 2020 ) . Control of Complement Activation by the Long Pentraxin PTX3: Implications in Age-Related Macular Degeneration . Frontiers in Pharmacology vol. 11 ,

Bonavita E, Bromley CP, Jonsson G, Pelly VS, Sahoo S, Walwyn-Brown K, Mensurado S, Moeini A et al. ( 2020 ) . Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade . Immunity vol. 53 , ( 6 ) 1215 - 1229.e8 .

Brunetta E, Folci M, Bottazzi B, De Santis M, Gritti G, Protti A, Mapelli SN, Bonovas S et al. ( 2020 ) . Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19 . Nature Immunology vol. 22 , ( 1 ) 19 - 24 .

Bachelerie F, Ben-Baruch A, Charo IF, Combadiere C, Förster R, Farber JM, Graham GJ, Horuk R et al. ( 2020 ) . Chemokine receptors (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database . IUPHAR/BPS Guide to Pharmacology CITE vol. 2020 , ( 5 )

Ashot DP, Sergey AH, Radik MB ( 2020 ) . Risk assessment of dietary exposure to potentially toxic trace elements in emerging countries: A pilot study on intake via flour-based products in Yerevan, Armenia . Food and Chemical Toxicology vol. 146 ,

Siddiqui I, Vignali D, Kallikourdis M, Mantovani A, Allavena P ( 2020 ) . Adoptive T-Cell Therapy: Optimizing Chemokine Receptor-Mediated Homing of T-Cells in Cancer Immunotherapy . Cancer Immunology , Springer Nature

Cortese N, Carriero R, Laghi L, Marchesi F ( 2020 ) . Prognostic significance of tumor-associated macrophages: past, present and future . Seminars in Immunology vol. 48 ,

Mantovani A, Netea MG ( 2020 ) . Trained Innate Immunity, Epigenetics, and Covid-19 . The New England Journal of Medicine vol. 383 , ( 11 ) 1078 - 1080 .

Cortese N, Rigamonti A, Mantovani A ( 2020 ) . The neuro-immune axis in cancer: Relevance of the peripheral nervous system to the disease . Immunology Letters vol. 227 , 60 - 65 .

Donadon M, Torzilli G, Cortese N, Soldani C, Di Tommaso L, Franceschini B, Carriero R, Barbagallo M et al. ( 2020 ) . Macrophage morphology correlates with single-cell diversity and prognosis in colorectal liver metastasis . Journal of Experimental Medicine vol. 217 , ( 11 )

De Santis M, Mantovani A, Selmi C ( 2020 ) . The other side of the innate immune system: humoral arms favoring cancer . Cellular & Molecular Immunology vol. 17 , ( 10 ) 1024 - 1025 .

Jaillon S, Ponzetta A, Di Mitri D, Santoni A, Mantovani A ( 2020 ) . Neutrophil diversity and plasticity in tumour progression and therapy . Nature Reviews Cancer vol. 20 , ( 9 ) 485 - 503 .

Corbetta L, Fabbri LM, Li S, Li J, Cao B, Yang J, Agnelli G, Giustozzi M et al. ( 2020 ) . Stand on the Same Side Against Covid – 19 Clinical Management of Covid-19 . Substantia1022 - 1022 .

Pipoyan D, Stepanyan S, Beglaryan M, Stepanyan S ( 2020 ) . Health risk assessment of toxicologically relevant residues in emerging countries: A pilot study on Malachite Green residues in farmed freshwater fish of Armenia . Food and Chemical Toxicology vol. 143 ,

Asselta R, Paraboschi EM, Mantovani A, Duga S ( 2020 ) . ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy . Aging vol. 12 , ( 11 ) 10087 - 10098 .

Cecconi M, Forni G, Mantovani A ( 2020 ) . Ten things we learned about COVID-19 . Intensive Care Medicine vol. 46 , ( 8 ) 1590 - 1593 .

Mantovani A, Piana F, Lombardo V ( 2020 ) . Ontology-driven representation of knowledge for geological maps . Computers & Geosciences vol. 139 ,

Meessen JMTA, Cardinale D, Ciceri F, Sandri MT, Civelli M, Bottazzi B, Cucchi G, Menatti E et al. ( 2020 ) . Circulating biomarkers and cardiac function over 3 years after chemotherapy with anthracyclines: the ICOS‐ONE trial . ESC Heart Failure vol. 7 , ( 4 ) 1452 - 1466 .

Galvan D, Cremasco H, Mantovani ACG, Bona E, Killner M, Borsato D ( 2020 ) . Kinetic study of the transesterification reaction by artificial neural networks and parametric particle swarm optimization . Fuel vol. 267 ,

Cini C, Bortot G, Sforza S, Mantovani A, Landi L, Esposito C, Escolino M, Masieri L ( 2020 ) . Paediatric urology practice during COVID-19 pandemic . Journal of Pediatric Urology vol. 16 , ( 3 ) 295 - 296 .

Bardasi G, Romagnoli A, Foschini MP, Mantovani A, Alvisi P ( 2020 ) . Pyostomatitis vegetans in a pediatric patient with ulcerative colitis: case report of a rare pediatric inflammatory bowel disease extraintestinal manifestation and review of the literature . European Journal of Gastroenterology & Hepatology vol. 32 , ( 7 ) 889 - 892 .

Asselta R, Paraboschi EM, Mantovani A ( 2020 ) . ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy .

Cortese N, Capretti G, Barbagallo M, Rigamonti A, Takis PG, Castino GF, Vignali D, Maggi G et al. ( 2020 ) . Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1+ Cells . Cancer Immunology Research . vol. 8 , 493 - 505 .

Morandi A, Zambon A, Di Santo SG, Mazzone A, Cherubini A, Mossello E, Bo M, Marengoni A et al. ( 2020 ) . Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia . Journal of the American Medical Directors Association vol. 21 , ( 4 ) 486 - 492.e6 .

Corbetta L, Fabbri LM, Cavalieri D, Bonanni P, Mantovani A, Thompson B, Luo F ( 2020 ) . Stand on the Same Side Against Covid - 19: Scientific Evidence on Vaccine for Covid-19 . Substantia vol. 4 , ( 1 )

Inforzato A, Baldock C, Jowitt TA, Holmes DF, Lindstedt R, Marcellini M, Rivieccio V, Briggs DC et al. ( 2020 ) . Correction: The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2 . J Biol Chem vol. 295 , ( 6 )

Lombardi R, Airaghi L, Targher G, Serviddio G, Maffi G, Mantovani A, Maffeis C, Colecchia A et al. ( 2020 ) . NAFLD fibrosis score identifies not only advanced liver fibrosis but also chronic vascular complications in type 2 diabetic patients . Digestive and Liver Disease . vol. 52 ,

健二 太, 隆雄 浜, Bottazzi B, Mantovani A ( 2020 ) . S3-1 ペントラキシン3(PTX3)複合体による自然免疫系の宿主防御機構 . Medical Mycology Journal

Horuk R, Mantovani A, Sozzani S, Proost P, Van Damme J ( 2020 ) . The Monocyte Chemoattractant Protein Family . Chemoattractant Ligands and Their Receptors , Taylor & Francis

Tavares LP, Garcia CC, Gonçalves APF, Kraemer LR, Melo EM, Oliveira FMS, Freitas CS, Lopes GAO et al. ( 2020 ) . ACKR2 contributes to pulmonary dysfunction by shaping CCL5:CCR5-dependent recruitment of lymphocytes during influenza A infection in mice . American Journal of Physiology - Lung Cellular and Molecular Physiology vol. 318 , ( 4 ) l655 - l670 .

Gulic T, Silva-Gomes R, Davoudian S, Sironi M, Allavena P, Mantovani A, Bottazzi B ( 2020 ) . Tumor-Associated Myeloid Cells in Cancer Progression . Cancer Immunology , Springer Nature

Asselta R, Paraboschi EM, Mantovani A, Duga S ( 2020 ) . <i>ACE2</i> and <i>TMPRSS2</i> Variants and Expression as Candidates to Sex and Country Differences in COVID-19 Severity in Italy .

Bordin M, Cremasco H, Galvan D, Clemente M, Bona E, Mantovani AC, Borsato D ( 2020 ) . Simultaneous Transfer of Na+, K+, and Fe2+ Ions During Salting of Precooked Mushroom (Agaricus bisporus): Mathematical Modeling, Optimization, and Experimental Validation . Journal of the Brazilian Chemical Society

Spacino K, Mantovani AC, Marcheafave G, Canesin E, Borsato D ( 2020 ) . The Catalytic Action of Copper Ions and the Rosemary Extract Antioxidant Effect in the Biodiesel Oxidation Reaction and the Implication in Arrhenius Behavior . Journal of the Brazilian Chemical Society

Weiner J, Lewis DJM, Maertzdorf J, Mollenkopf H-J, Bodinham C, Pizzoferro K, Linley C, Greenwood A et al. ( 2019 ) . Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium . Scientific Reports vol. 9 , ( 1 )

Zatta M, Di Bella S, Bottazzi B, Rossi F, D’Agaro P, Segat L, Fabbiani M, Mantovani A et al. ( 2019 ) . Determination of pentraxin 3 levels in cerebrospinal fluid during central nervous system infections . European Journal of Clinical Microbiology & Infectious Diseases vol. 39 , ( 4 ) 665 - 670 .

Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW et al. ( 2019 ) . Chronic inflammation in the etiology of disease across the life span . Nature Medicine vol. 25 , ( 12 ) 1822 - 1832 .

Bachelerie F, Ben-Baruch A, Charo IF, Combadiere C, Förster R, Farber JM, Graham GJ, Hills R et al. ( 2019 ) . Chemokine receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database . IUPHAR/BPS Guide to Pharmacology CITE vol. 2019 , ( 5 )

Parente R, Sobacchi C, Bottazzi B, Mantovani A, Grčevic D, Inforzato A ( 2019 ) . The Long Pentraxin PTX3 in Bone Homeostasis and Pathology . Frontiers in Immunology vol. 10 ,

Del Prete A, Sozio F, Schioppa T, Ponzetta A, Vermi W, Calza S, Bugatti M, Salvi V et al. ( 2019 ) . The Atypical Receptor CCRL2 Is Essential for Lung Cancer Immune Surveillance . Cancer Immunology Research vol. 7 , ( 11 ) 1775 - 1788 .

Cossarizza A, Chang H-D, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N et al. ( 2019 ) . Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) . European Journal of Immunology vol. 49 , ( 10 ) 1457 - 1973 .

Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G et al. ( 2019 ) . Author Correction: ‘Stealth’ corporate innovation: an emerging threat for therapeutic drug development . Nature Immunology vol. 20 , ( 11 ) 1556 - 1556 .

Donadon M, Di Tommaso L, Cortese N, Soldani C, Franceschini B, Carriero R, Barbagallo M, Rigamonti A et al. ( 2019 ) . 607P Morphology of tumour-associated macrophages dictates the prognosis of patients with colorectal liver metastases . Annals of Oncology vol. 30 ,

Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G et al. ( 2019 ) . ‘Stealth’ corporate innovation: an emerging threat for therapeutic drug development . Nature Immunology vol. 20 , ( 11 ) 1409 - 1413 .

Locati M, Curtale G ( 2019 ) . Diversity, Mechanisms, and Significance of Macrophage Plasticity . Annual Review of Pathology Mechanisms of Disease vol. 15 , ( 1 ) 1 - 25 .

Pulsatelli L, Boiardi L, Assirelli E, Pazzola G, Muratore F, Addimanda O, Dolzani P, Versari A et al. ( 2019 ) . Imbalance between angiogenic and anti-angiogenic factors in sera from patients with large-vessel vasculitis . Clinical and Experimental Rheumatology vol. 38 Suppl 124 , ( 2 ) 23 - 30 .

Bachelerie F, Ben-Baruch A, Charo IF, Combadiere C, Förster R, Farber JM, Graham GJ, Horuk R et al. ( 2019 ) . Chemokine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database . IUPHAR/BPS Guide to Pharmacology CITE vol. 2019 , ( 4 )

Pinto ML, Rios E, Durães C, Ribeiro R, Machado JC, Mantovani A, Barbosa MA, Carneiro F et al. ( 2019 ) . The Two Faces of Tumor-Associated Macrophages and Their Clinical Significance in Colorectal Cancer . Frontiers in Immunology vol. 10 ,

Ascierto PA, Butterfield LH, Demaria S, Ferris RL, Freeman GJ, Lo RS, Mantovani A, Nathan P et al. ( 2019 ) . The great debate at “Immunotherapy Bridge 2018”, Naples, November 29th, 2018 . Journal for ImmunoTherapy of Cancer vol. 7 , ( 1 )

Donadon M, Cortese N, Marchesi F, Cimino M, Mantovani A, Torzilli G ( 2019 ) . Hepatobiliary surgeons meet immunologists: the case of colorectal liver metastases patients . HepatoBiliary Surgery and Nutrition vol. 8 , ( 4 ) 370 - 377 .

Moregola A, Bonacina F, Baragetti A, Porte R, Sironi M, Grigore L, Pellegatta F, Bottazzi B et al. ( 2019 ) . Pentraxin 3 Plays A Key Role In The Immunomodulation Of Diet Induced-Obesity In Mice . Atherosclerosis . vol. 287 ,

Ramirez GA, Rovere-Querini P, Blasi M, Sartorelli S, Di Chio MC, Baldini M, De Lorenzo R, Bozzolo EP et al. ( 2019 ) . Corrigendum: PTX3 Intercepts Vascular Inflammation in Systemic Immune-Mediated Diseases . Frontiers in Immunology vol. 10 ,

Mattiola I, Tomay F, De Pizzol M, Silva-Gomes R, Savino B, Gulic T, Doni A, Lonardi S et al. ( 2019 ) . The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell–mediated resistance to metastasis . Nature Immunology vol. 20 , ( 8 ) 1012 - 1022 .

Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, Magrini E, Gianni F et al. ( 2019 ) . Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors . Cell vol. 178 , ( 2 ) 346 - 360.e24 .

Digifico E, Belgiovine C, Mantovani A, Allavena P ( 2019 ) . Microenvironment and Immunology of the Human Pleural Malignant Mesothelioma . Mesothelioma , Springer Nature

Riva F, Ponzoni M, Supino D, Bertilaccio MTS, Massara M, Pasqualini F, Carriero R, Innocenzi A et al. ( 2019 ) . IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development . Cancer Immunology Research vol. 7 , ( 6 ) 874 - 885 .

Mantovani A, Bonecchi R ( 2019 ) . One Clever Macrophage Checkpoint . Clinical Cancer Research vol. 25 , ( 11 ) 3202 - 3204 .

Ramirez GA, Tombetti E, Rovere-Querini P, Blasi M, Baldini M, De Lorenzo R, Bozzolo E, Leone R et al. ( 2019 ) . THU0005 PTX3 AS A UNIVERSAL MARKER OF VASCULAR INFLAMMATION IN MULTIPLE IMMUNE-MEDIATED DISEASES . Annals of the Rheumatic Diseases . vol. 78 , 269 - 270 .

Ramirez GA, Rovere-Querini P, Blasi M, Sartorelli S, Di Chio MC, Baldini M, De Lorenzo R, Bozzolo EP et al. ( 2019 ) . PTX3 Intercepts Vascular Inflammation in Systemic Immune-Mediated Diseases . Frontiers in Immunology vol. 10 ,

Dejana E, Languino LR, Colella S, Erroi A, Mantovani A, Marguerie G, Maes L ( 2019 ) . Migration of cultured endothelial cells in response to fibrinogen . Fibrin formation and Fibrinolysis , De Gruyter

Cavalleri T, Bianchi P, Basso G, Celesti G, Grizzi F, Bossi P, Greco L, Pitrone C et al. ( 2019 ) . Combined low densities of FoxP3+ and CD3+ tumor-infiltrating lymphocytes identify stage II colorectal cancer at high risk of progression . Cancer Immunology Research vol. 7 , ( 5 )

Ristagno G, Fumagalli F, Bottazzi B, Mantovani A, Olivari D, Novelli D, Latini R ( 2019 ) . Pentraxin 3 in Cardiovascular Disease . Frontiers in Immunology vol. 10 ,

Pio R, Ajona D, Ortiz-Espinosa S, Mantovani A, Lambris JD ( 2019 ) . Complementing the Cancer-Immunity Cycle . Frontiers in Immunology vol. 10 ,

Porte R, Davoudian S, Asgari F, Parente R, Mantovani A, Garlanda C, Bottazzi B ( 2019 ) . The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis . Frontiers in Immunology vol. 10 ,

Doni A, Stravalaci M, Inforzato A, Magrini E, Mantovani A, Garlanda C, Bottazzi B ( 2019 ) . The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer . Frontiers in Immunology vol. 10 ,

Mantovani A, Dinarello CA, Molgora M ( 2019 ) . Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity . Immunity vol. 50 , ( 4 ) 778 - 795 .

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Kouba M, Durjava MK et al. ( 2019 ) . Safety and efficacy of l‐lysine monohydrochloride and l‐lysine sulfate produced using Corynebacterium glutamicum CCTCC M 2015595 for all animal species . EFSA Journal vol. 17 , ( 3 )

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Kouba M, Durjava MK et al. ( 2019 ) . Safety and efficacy of l‐tryptophan produced with Escherichia coli CGMCC 11674 for all animal species . EFSA Journal vol. 17 , ( 3 )

Batista NV, Barbagallo M, Oliveira VLS, Castro-Gomes T, Oliveira RDR, Louzada-Junior P, Pinheiro GRC, Mantovani A et al. ( 2019 ) . The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals . The Journal of Immunology vol. 202 , ( 6 ) 1807 - 1814 .

Mantovani A, Ponzetta A, Inforzato A, Jaillon S ( 2019 ) . Innate immunity, inflammation and tumour progression: double‐edged swords . Journal of Internal Medicine vol. 285 , ( 5 ) 524 - 532 .

Bonacina F, Moregola A, Porte R, Baragetti A, Bonavita E, Salatin A, Grigore L, Pellegatta F et al. ( 2019 ) . Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity . Cardiovascular Research vol. 115 , ( 13 ) 1861 - 1872 .

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Kouba M, Durjava MK et al. ( 2019 ) . Efficacy of methyl ester of conjugated linoleic acid (t10,c12 isomer) for sows and cows for reproduction . EFSA Journal vol. 17 , ( 3 )

Laplane L, Mantovani P, Adolphs R, Chang H, Mantovani A, McFall-Ngai M, Rovelli C, Sober E et al. ( 2019 ) . Why science needs philosophy . Proceedings of the National Academy of Sciences of the United States of America vol. 116 , ( 10 ) 3948 - 3952 .

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Kouba M, Durjava MK et al. ( 2019 ) . Safety and efficacy of l‐valine produced using Corynebacterium glutamicum CGMCC 11675 for all animal species . EFSA Journal vol. 17 , ( 3 )

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Kouba M, Durjava MK, López‐Alonso M et al. ( 2019 ) . Safety and efficacy of l‐threonine produced by fermentation with Corynebacterium glutamicum ■■■■■ for all animal species . EFSA Journal vol. 17 , ( 3 )

Maeda A, Digifico E, Andon FT, Mantovani A, Allavena P ( 2019 ) . Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor‐conditioned macrophages . European Journal of Immunology vol. 49 , ( 5 ) 801 - 811 .

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Kouba M, Durjava MK et al. ( 2019 ) . Assessment of the application for renewal of authorisation of Lantharenol® (lanthanum carbonate octahydrate) for cats . EFSA Journal vol. 17 , ( 1 )

Maffia P, Mantovani A, Spedding M ( 2018 ) . Scientists on the Spot: the Guide to Immunopharmacology as a new resource for the cardiovascular community . Cardiovascular Research vol. 115 , ( 1 ) e5 - e6 .

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Kouba M, Durjava MK et al. ( 2018 ) . Safety and efficacy of vitamin B2 (riboflavin 5′‐phosphate ester monosodium salt) for all animal species when used in water for drinking . EFSA Journal vol. 16 , ( 12 )

Rappuoli R, Santoni A ( 2018 ) . Vaccines: An achievement of civilization, a human right, our health insurance for the future . Journal of Experimental Medicine vol. 216 , ( 1 ) 7 - 9 .

Bottazzi B, Riboli E, Mantovani A ( 2018 ) . Aging, inflammation and cancer . Seminars in Immunology vol. 40 , 74 - 82 .

Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, Ghirardini E, Filipello F et al. ( 2018 ) . Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1‐integrin . The EMBO Journal vol. 38 , ( 1 )

Mantovani A, Longo DL ( 2018 ) . Macrophage Checkpoint Blockade in Cancer — Back to the Future . The New England Journal of Medicine vol. 379 , ( 18 ) 1777 - 1779 .

Feed EPOAAPOSUIA, Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H, Dusemund B, Kouba M, Durjava MK et al. ( 2018 ) . Safety and efficacy of l‐threonine produced by fermentation using Escherichia coli CGMCC 7.232 for all animal species . EFSA Journal vol. 16 , ( 10 )

Bonacina F, Barbieri SS, Cutuli L, Amadi P, Don A, Sironi M, Tartari S, Mantovani A et al. ( 2018 ) . Corrigendum to “Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation” [Biochim. Biophys. Acta, 1862 (2016) 1182–1190] . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease vol. 1865 , ( 1 )

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Bonavita O, Poeta VM, Massara M, Mantovani A, Bonecchi R ( 2018 ) . Regulation of hematopoiesis by the chemokine system . Cytokine vol. 109 , 76 - 80 .

Semeraro N, Errori A, Casali B, Dontati MB, Mantovani A ( 1987 ) . DEFECTIVE GENERATION OF PROCOAGULANT ACTIVITY BY TUMOR-ASSOCIATED MACROPHAGES EXPOSED TO DIFFERENT STIMULI . Thrombosis and Haemostasis . Conference: XIth International Congress on Thrombosis and Haemostasis vol. 58 , 235 - 235 .

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Bonacina F, Moregola A, Baragetti A, Bonavita E, Garlaschelli K, Salatin A, Grigore L, Pellegatta F et al. ( 2018 ) . The long pentraxin 3 (PTX3) plays a key role in the immunomodulation of diet induced-obesity in mice . Atherosclerosis . vol. 275 ,

Marelli G, Avigni R, Allavena P, Garlanda C, Mantovani A, Doni A, Erreni M ( 2018 ) . Optical in vivo imaging detection of preclinical models of gut tumors through the expression of integrin αVβ3 . Oncotarget vol. 9 , ( 59 ) 31380 - 31396 .

Colucci M, Giavazzi R, Alessandri G, Semeraro N, Mantovani A, Donati MB ( 1981 ) . Procoagulant (Tissue Factor) Activity Is Higher In Cells From Murine Sarcoma Sublines With Lower Metastatic Potential . Thrombosis and Haemostasis . Conference: Oral Presentations vol. 46 , 033 - 033 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Scientific Opinion on the safety and efficacy of Aviax 5% (semduramicin sodium) for chickens for fattening . EFSA Journal vol. 16 , ( 7 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Assessment of the application for renewal of authorisation of Calsporin® (Bacillus subtilis DSM 15544) for chickens for fattening . EFSA Journal vol. 16 , ( 7 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of vitamin B12 (in the form of cyanocobalamin) produced by Ensifer spp. as a feed additive for all animal species based on a dossier submitted by VITAC EEIG . EFSA Journal vol. 16 , ( 7 )

Mantovani A, Sozzani S, Vecchi A, Introna M, Allavena P ( 2018 ) . Cytokine Activation of Endothelial Cells: New Molecules for an Old Paradigm . Thrombosis and Haemostasis vol. 78 , ( 01 ) 406 - 414 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of betaine anhydrous for food‐producing animal species based on a dossier submitted by AB Vista . EFSA Journal vol. 16 , ( 7 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of vitamin B2 (riboflavin) produced by Ashbya gossypii DSM 23096 for all animal species based on a dossier submitted by BASF SE . EFSA Journal vol. 16 , ( 7 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, De Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Assessment of the application for renewal of authorisation of Actisaf® Sc47 (Saccharomyces cerevisiae CNCM I‐4407) for lambs for fattening, minor dairy ruminants, horses and pigs for fattening . EFSA Journal vol. 16 , ( 7 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of COXAM® (amprolium hydrochloride) for chickens for fattening and chickens reared for laying . EFSA Journal vol. 16 , ( 7 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Chesson A, Flachowsky G et al. ( 2018 ) . Safety and efficacy of muramidase from Trichoderma reesei DSM 32338 as a feed additive for chickens for fattening and minor poultry species . EFSA Journal vol. 16 , ( 7 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Modification of the terms of authorisation of lecithins as a feed additive for all animal species . EFSA Journal vol. 16 , ( 6 )

Mantovani A ( 2018 ) . Characterization and Management of Uncertainties in Toxicological Risk Assessment: Examples from the Opinions of the European Food Safety Authority . Methods in Molecular Biology vol. 1800 , 219 - 229 .

Street ME, Angelini S, Bernasconi S, Burgio E, Cassio A, Catellani C, Cirillo F, Deodati A et al. ( 2018 ) . Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting . International Journal of Molecular Sciences vol. 19 , ( 6 )

Cortese N, Castino G, Capretti G, Takis P, Gavazzi F, Ridolfi C, Nappo G, Maggi G et al. ( 2018 ) . Metabolomics analysis of pancreatic juice indicates an alteration in glucose metabolism in pancreatic ductal adenocarcinoma patients . Pancreatology vol. 18 , ( 4 )

Parente R, Bottazzi B, Mantovani A, Inforzato A ( 2018 ) . PTX3 . Encyclopedia of Signaling Molecules , Springer Nature

Ramirez GA, Bozzolo EP, Canti V, Bottazzi B, Mantovani A, Dagna L, Rovere-Querini P, Manfredi AA ( 2018 ) . SAT0435 Plasma ptx3 levels correlate with systemic lupus erythematosus activity and are influenced by corticosteroids . Annals of the Rheumatic Diseases vol. 77 ,

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of l‐arginine produced by fermentation using Corynebacterium glutamicum KCCM 10741P for all animal species . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of l‐arginine produced by fermentation with Escherichia coli NITE BP‐02186 for all animal species . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Hemicell® HT (endo‐1,4‐β‐mannanase) as a feed additive for chickens for fattening, chickens reared for laying, turkey for fattening, turkeys reared for breeding, weaned piglets, pigs for fattening and minor poultry and porcine species . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Cocconcelli PS, Flachowsky G et al. ( 2018 ) . Safety and efficacy of Kelforce® (l‐glutamic acid, N,N‐diacetic acid, tetrasodium salt (GLDA‐Na4)) as a feed additive for chickens for fattening . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of Taminizer D (dimethylglycine sodium salt) as a feed additive for chickens for fattening . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of cumin tincture (Cuminum cyminum L.) when used as a sensory additive for all animal species . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of fumonisin esterase from Komagataella phaffii DSM 32159 as a technological feed additive for pigs and poultry . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Chesson A, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of Amylofeed® (endo‐1,3(4)‐β‐glucanase and endo‐1,4‐β‐xylanase and α‐amylase) as a feed additive for piglets and minor growing porcine species . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Lactobacillus acidophilus D2/CSL (Lactobacillus acidophilus CECT 4529) as a feed additive for cats and dogs . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Guidance on the assessment of the efficacy of feed additives . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Bacillus subtilis KCCM 10673P and Aspergillus oryzae KCTC 10258BP when used as a technological feed additive for all animal species . EFSA Journal vol. 16 , ( 5 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety of natural mixture of dolomite plus magnesite and magnesium‐phyllosilicates (Fluidol) for all animal species . EFSA Journal vol. 16 , ( 5 )

Zhang M, Li X, Kahyaoglu S, Sironi M, Mantovani A ( 2018 ) . Cardiac endothelial cells produce complement C3 in response to hypoxia . The Journal of Immunology vol. 200 , ( Supplement_1 ) 166.40 - 166.40 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of alpha‐amylase from Bacillus amyloliquefaciens DSM 9553, Bacillus amyloliquefaciens NCIMB 30251, Aspergillus oryzae CBS 585.94 and Aspergillus oryzae ATTC SD‐5374, endo‐1,4‐beta‐glucanase from Trichoderma reesei ATCC PTA‐10001, Trichoderma reesei ATCC SD‐6331 and Aspergillus niger CBS 120604, endo‐1,4‐beta‐xylanase from Trichoderma koningii MUCL 39203 and Trichoderma citrinoviride CBS 614.94 and endo‐1,3(4)‐beta‐glucanase from Aspergillus tubingensis MUCL 39199 as silage additives for all animal species . EFSA Journal vol. 16 , ( 4 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Chesson A, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of EB15 10 (Bacillus subtilis DSM 25841) as a feed additive for weaned piglets and minor porcine species . EFSA Journal vol. 16 , ( 4 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of ZM16 10 (Bacillus amyloliquefaciens DSM 25840) as a feed additive for weaned piglets and minor porcine species . EFSA Journal vol. 16 , ( 4 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Coxar® (nicarbazin) for turkeys for fattening . EFSA Journal vol. 16 , ( 4 )

Tamassia N, Arruda-Silva F, Calzetti F, Lonardi S, Gasperini S, Gardiman E, Bianchetto-Aguilera F, Gatta LB et al. ( 2018 ) . A Reappraisal on the Potential Ability of Human Neutrophils to Express and Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It . Frontiers in Immunology vol. 9 ,

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Bacillus subtilis DSM 28343 as a feed additive for calves for rearing . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Coxiril® (diclazuril) for chickens reared for laying . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of ponceau 4R for cats, dogs and ornamental fish . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Guidance on the characterisation of microorganisms used as feed additives or as production organisms . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, De Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Bacillus subtilis DSM 28343 as a feed additive for piglets . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Calsporin® (Bacillus subtilis DSM 15544) as a feed additive for pigs for fattening . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of ECONASE® XT (endo‐1,4‐β‐xylanase) as a feed additive for laying hens . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of ECONASE® XT (endo‐1,4‐β‐xylanase) as a feed additive for pigs for fattening . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, De Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Lactococcus lactis NCIMB 30160 as a feed additive for all animal species . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of butylated hydroxyanisole (BHA) as a feed additive for all animal species . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety of vitamin B2 (80%) as riboflavin produced by Bacillus subtilis KCCM‐10445 for all animal species . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Coxiril® (diclazuril) for pheasants . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Sacox® microGranulate (salinomycin sodium) for rabbits for fattening . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of sodium saccharin when used as a feed flavour for piglets, pigs for fattening, calves for rearing and calves for fattening . EFSA Journal vol. 16 , ( 3 )

Moretta L, Mantovani A ( 2018 ) . Alessandro Moretta 1953–2018 . Nature Immunology vol. 19 , ( 4 ) 315 - 315 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, De Lourdes Bastos M, Chesson A, Cocconcelli PS et al. ( 2018 ) . Efficacy of Cylactin® (Enterococcus faecium NCIMB 10415) as a feed additive for pigs for fattening . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, De Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Alterion NE® (Bacillus subtilis DSM 29784) as a feed additive for minor poultry species for fattening and reared for laying . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Pediococcus pentosaceus DSM 32291 as a silage additive for all animal species . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of hydroxy analogue of methionine and its calcium salt (ADRY+®) for all animal species . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of natural mixtures of talc (steatite) and chlorite (E 560) as a feed additive for all animal species . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2018 ) . Safety and efficacy of benzoic acid for pigs and poultry . EFSA Journal vol. 16 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Chesson A, Cocconcelli PS et al. ( 2018 ) . Safety and efficacy of 3‐phytase FLF1000 as a feed additive for chickens reared for laying and minor poultry species . EFSA Journal vol. 16 , ( 3 )

Grčević D, Sironi M, Valentino S, Deban L, Cvija H, Inforzato A, Kovačić N, Katavić V et al. ( 2018 ) . The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair . Frontiers in Immunology vol. 9 ,

Bodduluri SR, Mathis S, Maturu P, Krishnan E, Satpathy SR, Chilton PM, Mitchell TC, Lira S et al. ( 2018 ) . Mast Cell–Dependent CD8+ T-cell Recruitment Mediates Immune Surveillance of Intestinal Tumors in ApcMin/+ Mice . Cancer Immunology Research vol. 6 , ( 3 ) 332 - 347 .

Mantovani A ( 2018 ) . The inflammation – cancer connection . The FEBS Journal vol. 285 , ( 4 ) 638 - 640 .

Russo RC, Savino B, Mirolo M, Buracchi C, Germano G, Anselmo A, Zammataro L, Pasqualini F et al. ( 2018 ) . The atypical chemokine receptor ACKR2 drives pulmonary fibrosis by tuning influx of CCR2+ and CCR5+ IFNγ-producing γδT cells in mice . American Journal of Physiology - Lung Cellular and Molecular Physiology vol. 314 , ( 6 ) l1010 - l1025 .

Massara M, Bonavita O, Savino B, Caronni N, Mollica Poeta V, Setten E, Recordati C, Crisafulli L ( 2018 ) . ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity . Nature Communications vol. 9 , ( 1 )

Garlanda C, Bottazzi B, Magrini E, Inforzato A ( 2018 ) . PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer . Physiological Reviews vol. 98 , ( 2 ) 623 - 639 .

Mantovani A ( 2018 ) . Mandatory vaccination in Italy: Time for engagement of immunologists . European Journal of Immunology vol. 48 , ( 1 ) 12 - 14 .

Mantovani A ( 2018 ) . Cancer-Related Inflammation in Tumor Progression . Reference Module in Biomedical Sciences , Elsevier

Mantovani A ( 2017 ) . Redundancy and robustness versus division of labour and specialization in innate immunity . Seminars in Immunology vol. 36 , 28 - 30 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety and efficacy of bentonite as a feed additive for all animal species . EFSA Journal vol. 15 , ( 12 )

Mantovani A, Barajon I, Garlanda C ( 2017 ) . IL‐1 and IL‐1 regulatory pathways in cancer progression and therapy . Immunological Reviews vol. 281 , ( 1 ) 57 - 61 .

Molgora M, Supino D ( 2017 ) . Tuning inflammation and immunity by the negative regulators IL‐1R2 and IL‐1R8 . Immunological Reviews vol. 281 , ( 1 ) 233 - 247 .

Del Prete A, Locati M, Otero K, Riboldi E, Mantovani A, Vecchi A, Sozzani S ( 2017 ) . Migration of dendritic cells across blood and lymphatic endothelial barriers . Thrombosis and Haemostasis vol. 95 , ( 01 ) 22 - 28 .

Galdiero MR, Varricchi G, Loffredo S, Mantovani A, Marone G ( 2017 ) . Roles of neutrophils in cancer growth and progression . Journal of Leukocyte Biology vol. 103 , ( 3 ) 457 - 464 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Assessment of the application for renewal of authorisation of VevoVitall® (benzoic acid) as feed additive for weaned piglets and pigs for fattening . EFSA Journal vol. 15 , ( 12 )

Carriero R, Garlanda C, Mantovani A ( 2017 ) . Interleukin-37 signaling . Reactome - a curated knowledgebase of biological pathways vol. 63 ,

Ponzetta A, Mantovani A, Jaillon S ( 2017 ) . Dissecting neutrophil complexity in cancer . Emerging Topics in Life Sciences vol. 1 , ( 5 ) 457 - 470 .

Haks MC, Bottazzi B, Cecchinato V, De Gregorio C, Del Giudice G, Kaufmann SHE, Lanzavecchia A, Lewis DJM et al. ( 2017 ) . Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination . Frontiers in Immunology vol. 8 ,

Siddiqui I, Erreni M, Kamal MA, Porta C, Marchesi F, Pesce S, Pasqualini F, Schiarea S et al. ( 2017 ) . Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition . OncoImmunology vol. 7 , ( 2 )

Mantovani A, Garlanda C, Bottazzi B ( 2017 ) . Pentraxins in the Orchestration of Defense and Tissue Repair during the Acute Phase Response . Inflammation - From Molecular and Cellular Mechanisms to the Clinic , Wiley

Molgora M, Bonavita E, Ponzetta A, Riva F, Barbagallo M, Jaillon S, Popović B, Magrini E et al. ( 2017 ) . IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity . Nature vol. 551 , ( 7678 ) 110 - 114 .

Mantovani A ( 2017 ) . Wandering pathways in the regulation of innate immunity and inflammation . Journal of Autoimmunity vol. 85 , 1 - 5 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety and efficacy of RONOZYME® WX (endo‐1,4‐β‐xylanase) as a feed additive for laying hens . EFSA Journal vol. 15 , ( 10 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Guidance on the assessment of the safety of feed additives for the consumer . EFSA Journal vol. 15 , ( 10 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Guidance on the assessment of the safety of feed additives for the target species . EFSA Journal vol. 15 , ( 10 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Guidance on the identity, characterisation and conditions of use of feed additives . EFSA Journal vol. 15 , ( 10 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety and efficacy of AviMatrix® (benzoic acid, calcium formate and fumaric acid) for chickens for fattening, chickens reared for laying, minor avian species for fattening and minor avian species reared to point of lay . EFSA Journal vol. 15 , ( 10 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety and efficacy of VevoVitall® (benzoic acid) as feed additive for minor porcine species . EFSA Journal vol. 15 , ( 10 )

Erreni M, Manfredi AA, Garlanda C, Mantovani A ( 2017 ) . The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis . Immunological Reviews vol. 280 , ( 1 ) 112 - 125 .

Andón FT, Digifico E, Maeda A, Erreni M, Mantovani A, Alonso MJ, Allavena P ( 2017 ) . Targeting tumor associated macrophages: The new challenge for nanomedicine . Seminars in Immunology vol. 34 , 103 - 113 .

Reis ES, Mastellos DC, Ricklin D, Mantovani A, Lambris JD ( 2017 ) . Complement in cancer: untangling an intricate relationship . Nature Reviews Immunology vol. 18 , ( 1 ) 5 - 18 .

Cavalli G, Koenders M, Kalabokis V, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L et al. ( 2017 ) . Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation . Rheumatology vol. 56 , ( 12 ) 2256 - 2256 .

Inforzato A, Parente R, Petroni F, Sironi M, Leone R, Valentino S, Bottazzi B, Mantovani A ( 2017 ) . Complement factor H and the long pentraxin PTX3 cooperate in the immune response to Aspergillus fumigatus . Molecular Immunology . vol. 89 ,

Di Marco S, Magrini E, Berthenet K, Barbagallo ML, Polentarutti N, Ponzetta A, Mantovani A, Garlanda C ( 2017 ) . Role of complement in cancer-related inflammation . Molecular Immunology . vol. 89 ,

Marelli G, Erreni M, Anselmo A, Taverniti V, Guglielmetti S, Mantovani A, Allavena P ( 2017 ) . Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis . Cancer Research vol. 77 , ( 16 ) 4472 - 4485 .

Galdiero MR, Marone G, Mantovani A ( 2017 ) . Cancer Inflammation and Cytokines . Cold Spring Harbor Perspectives in Biology vol. 10 , ( 8 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety and efficacy of FRA® Octazyme C Dry (α‐galactosidase, α‐amylase, endo‐1,3(4)‐β‐glucanase, endo‐1,4‐β‐glucanase, mannan‐endo‐1,4‐β‐mannosidase, pectinase, protease, endo‐1,4‐β‐xylanase) for chickens for fattening and weaned piglets . EFSA Journal vol. 15 , ( 8 )

Del Prete A, Martínez-Muñoz L, Mazzon C, Toffali L, Sozio F, Bosisio D, Gazzurelli L, Salvi V et al. ( 2017 ) . The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage . Blood vol. 130 , ( 10 ) 1223 - 1234 .

Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS et al. ( 2017 ) . A guiding map for inflammation . Nature Immunology vol. 18 , ( 8 ) 826 - 831 .

Malesci A, Bianchi P, Celesti G, Basso G, Marchesi F, Grizzi F, Di G, Cavalleri T et al. ( 2017 ) . Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer . OncoImmunology vol. 6 , ( 12 )

Belgiovine C, Bello E, Liguori M, Craparotta I, Mannarino L, Paracchini L, Beltrame L, Marchini S et al. ( 2017 ) . Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models . British Journal of Cancer vol. 117 , ( 5 ) 628 - 638 .

Galdiero MR, Molgora M, Garlanda C, Marone G, Mantovani A ( 2017 ) . Abstract SY06-01: Tumor-associated myelomonocytic cells as therapeutic targets . Cancer Research . vol. 77 ,

Locati M, Mantovani A, Bonecchi R ( 2017 ) . Atypical matters in myeloid differentiation . Nature Immunology vol. 18 , ( 7 ) 711 - 712 .

Sica A, Mancino A, Larghi P, Rubino L, Solinas G, Allavena P, Mantovani A ( 2017 ) . Tumor-Associated Macrophages . Encyclopedia of Cancer , Springer Nature

Mantovani A, Barajon I ( 2017 ) . The Innate Immune System: Macrophages . Cancer Immunotherapy Principles and Practice , Springer Publishing Company

Rubino M, Kunderfranco P, Basso G, Greco CM, Pasqualini F, Serio S, Roncalli M, Laghi L et al. ( 2017 ) . Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer . OncoImmunology vol. 6 , ( 7 )

Campesato LF, Silva APM, Cordeiro L, Correa BR, Navarro FCP, Zanin RF, Marçola M, Inoue LT et al. ( 2017 ) . High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity . Oncotarget vol. 5 , ( 0 ) 49470 - 49483 .

Pavanello S, Stendardo M, Mastrangelo G, Bonci M, Bottazzi B, Campisi M, Nardini M, Leone R et al. ( 2017 ) . Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers . Frontiers in Immunology vol. 8 ,

Ceresoli GL, Mantovani A ( 2017 ) . Immune checkpoint inhibitors in malignant pleural mesothelioma . The Lancet Oncology vol. 18 , ( 5 ) 559 - 561 .

Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR et al. ( 2017 ) . Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells . Journal of Experimental Medicine vol. 214 , ( 5 ) 1559 - 1559 .

Uguccioni M, Teixeira MM, Locati M, Mantovani A ( 2017 ) . Editorial: Regulation of Inflammation, Its Resolution and Therapeutic Targeting . Frontiers in Immunology vol. 8 ,

Tomasoni R, Morini R, Lopez-Atalaya JP, Corradini I, Canzi A, Rasile M, Mantovani C, Pozzi D et al. ( 2017 ) . Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects . eLife vol. 6 ,

Sica A, Mantovani A, Allavena P, Solinas G, Rubino L, Larghi P, Mancino A ( 2017 ) . Tumor-Associated Macrophages . Encyclopedia of Cancer , Springer Nature

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety and efficacy of Pediococcus parvulus DSM 28875 as a silage additive for all animal species . EFSA Journal vol. 15 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety of Endofeed® DC (endo‐1,3(4)‐β‐glucanase and endo‐1,4‐β‐xylanase) as a feed additive for chickens for fattening, laying hens, pigs for fattening and minor poultry and porcine species . EFSA Journal vol. 15 , ( 3 )

Mauri T, Zambelli V, Cappuzzello C, Bellani G, Dander E, Sironi M, Castiglioni V, Doni A et al. ( 2017 ) . Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice . Intensive Care Medicine Experimental vol. 5 , ( 1 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species . EFSA Journal vol. 15 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety of vitamin D3 addition to feedingstuffs for fish . EFSA Journal vol. 15 , ( 3 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety of l‐tryptophan technically pure, produced by fermentation with Escherichia coli DSM 25084, KCCM 11132P and SARI12091203 for all animal species based on a dossier submitted by FEFANA Asbl . EFSA Journal vol. 15 , ( 2 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety of cassia gum as a feed additive for dogs and cats based on a dossier submitted by Glycomer GmbH . EFSA Journal vol. 15 , ( 2 )

Lussana F, Carobbio A, Salmoiraghi S, Guglielmelli P, Vannucchi AM, Bottazzi B, Leone R, Mantovani A et al. ( 2017 ) . Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera . Journal of Hematology & Oncology vol. 10 , ( 1 )

Cavalli G, Justice JN, Boyle KE, D’Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T et al. ( 2017 ) . Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance . Proceedings of the National Academy of Sciences of the United States of America vol. 114 , ( 9 ) 2313 - 2318 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety of l‐lysine sulfate produced by fermentation with Escherichia coli CGMCC 3705 for all animal species . EFSA Journal vol. 15 , ( 2 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety of cassia gum as a feed additive for dogs and cats based on a dossier submitted by Intercolloid (UK) Ltd . EFSA Journal vol. 15 , ( 2 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2017 ) . Safety of natural mixture of dolomite plus magnesite and magnesium‐phyllosilicates (Fluidol) for all animal species . EFSA Journal vol. 15 , ( 2 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Cocconcelli PS et al. ( 2017 ) . Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species . EFSA Journal vol. 15 , ( 2 )

Mantovani A, Marchesi F, Malesci A, Laghi L, Allavena P ( 2017 ) . Tumour-associated macrophages as treatment targets in oncology . Nature Reviews Clinical Oncology vol. 14 , ( 7 ) 399 - 416 .

Jaillon S, Bonavita E, Garlanda C, Mantovani A ( 2017 ) . Interplay between Myeloid Cells and Humoral Innate Immunity . Myeloid Cells in Health and Disease , American Society for Microbiology

Parente R, Bottazzi B, Mantovani A, Inforzato A ( 2016 ) . PTX3 . Encyclopedia of Signaling Molecules , Springer Nature

Jaillon S, Bonavita E, Garlanda C, Mantovani A ( 2016 ) . Interplay between Myeloid Cells and Humoral Innate Immunity . Microbiology Spectrum vol. 4 , ( 6 )

Caironi P, Masson S, Mauri T, Bottazzi B, Leone R, Magnoli M, Barlera S, Mamprin F et al. ( 2016 ) . Pentraxin 3 in patients with severe sepsis or shock: the ALBIOS trial . European Journal of Clinical Investigation vol. 47 , ( 1 ) 73 - 83 .

Bottai G, Raschioni C, Losurdo A, Di Tommaso L, Tinterri C, Torrisi R, Reis-Filho JS, Roncalli M et al. ( 2016 ) . An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers . Breast Cancer Research vol. 18 , ( 1 )

Greco R, Sala E, Crucitti L, Morelli M, Stanghellini MTL, Vago L, Assanelli AA, Giglio F et al. ( 2016 ) . Pentraxin 3 As a Novel Diagnostic and Prognostic Biomarker for Acute GvHD and Fungal Infections in Adult Allogeneic HSCT Recipients . Blood . vol. 128 ,

Mantovani A, Locati M ( 2016 ) . Macrophage Metabolism Shapes Angiogenesis in Tumors . Cell Metabolism vol. 24 , ( 6 ) 887 - 888 .

Vezzoli M, Sciorati C, Campana L, Monno A, Doglio MG, Rigamonti E, Corna G, Touvier T et al. ( 2016 ) . Clearance of Cell Remnants and Regeneration of Injured Muscle Depend on Soluble Pattern Recognition Receptor PTX3 . Molecular Medicine vol. 22 , ( 1 ) 809 - 820 .

Dander E, De Lorenzo P, Bottazzi B, Quarello P, Vinci P, Balduzzi A, Masciocchi F, Bonanomi S et al. ( 2016 ) . Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation . Oncotarget vol. 5 , ( 0 ) 82123 - 82138 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, De Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of Lactobacillus brevis NCIMB 42149 as a silage additive for all animal species . EFSA Journal vol. 14 , ( 11 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of a preparation of algae interspaced bentonite as a feed additive for all animal species . EFSA Journal vol. 14 , ( 11 )

Doni A, Garlanda C, Mantovani A ( 2016 ) . Innate immunity, hemostasis and matrix remodeling: PTX3 as a link . Seminars in Immunology vol. 28 , ( 6 ) 570 - 577 .

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of Feedlyve AGL (endo‐1,3(4)‐β‐glucanase) as a feed additive for chickens for fattening . EFSA Journal vol. 14 , ( 11 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of Feedlyve AXC (endo‐1,4‐β‐xylanase) as a feed additive for chickens for fattening . EFSA Journal vol. 14 , ( 11 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of Axtra® PHY 20000 TPT2 (6‐phytase) as a feed additive for poultry and porcine species . EFSA Journal vol. 14 , ( 11 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of B‐Act® (Bacillus licheniformis DSM 28710) for chickens for fattening and chickens reared for laying . EFSA Journal vol. 14 , ( 11 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of Natugrain® TS/TS L (endo‐1,4‐β‐xylanase and endo‐1,4‐β‐glucanase) as a feed additive for chickens reared for laying and minor poultry species for laying . EFSA Journal vol. 14 , ( 11 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of fumonisin esterase (FUMzyme®) as a technological feed additive for all avian species . EFSA Journal vol. 14 , ( 11 )

Feed EPOAAPOSUIA, Rychen G, Aquilina G, Azimonti G, Bampidis V, de Lourdes Bastos M, Bories G, Chesson A et al. ( 2016 ) . Safety and efficacy of selenium‐enriched yeast (Saccharomyces cerevisiae NCYC R397) for all animal species . EFSA Journal vol. 14 , ( 11 )

Bottai G, Raschioni C, Székely B, Di Tommaso L, Szász AM, Losurdo A, Győrffy B, Ács B et al. ( 2016 ) . AXL-associated tumor inflammation as a poor prognostic signature in chemotherapy-treated triple-negative breast cancer patients . npj Breast Cancer vol. 2 , ( 1 )

Mantovani A ( 2016 ) . Macrophage Metabolism Shapes Angiogenesis in Tumors . Cell Metabolism vol. 24 , ( 5 ) 653 - 654 .

Daigo K, Inforzato A, Barajon I, Garlanda C, Bottazzi B, Meri S, Mantovani A ( 2016 ) . Pentraxins in the activation and regulation of innate immunity . Immunological Reviews vol. 274 , ( 1 ) 202 - 217 .

Jie Y, Doni A, Hellerud BC, Mollnes TE, Mantovani A, Garred P ( 2016 ) . Collectin-12 and long pentraxin PTX3 crosstalk synergizes resistance against N. meningitides via the alternative pathway of complement . Immunobiology . vol. 221 ,

Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR et al. ( 2016 ) . The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells . Journal of Experimental Medicine vol. 213 , ( 10 ) 2167 - 2185 .

Bergamo P, Volpe MG, Lorenzetti S, Notari T, Cocca E, Cerullo S, Cerino P ( 2016 ) . Human semen as an early, sensitive biomarker of highly polluted living environment in healthy men: A pilot biomonitoring study on trace elements in blood and semen and their relationship with sperm quality and RedOx status . Reproductive Toxicology vol. 66 , 1 - 9 .

Bonacina F, Barbieri S, Cutuli L, Amadio P, Doni A, Sironi M, Tartari S, Bottazzi B et al. ( 2016 ) . Pentraxin 3 deficiency is associated with increased arterial thrombosis in animal models . Atherosclerosis . vol. 252 , e250 - e251 .

Moregola A, Bonacina F, Guerrini U, Bonavita E, Garlanda C, Mantovani A, Catapano AL, Norata GD ( 2016 ) . Pentraxin 3 plays a key role in the immunomodulation of diet induced-obesity in mice . Atherosclerosis . vol. 252 , e229 - e230 .

Cavalli G, Koenders M, Kalabokis V, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L et al. ( 2016 ) . Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation . Rheumatology vol. 55 , ( 12 ) 2220 - 2229 .

Bonecchi R, Garlanda C, Riva F ( 2016 ) . Cytokine decoy and scavenger receptors as key regulators of immunity and inflammation . Cytokine vol. 87 , 37 - 45 .

Marelli G, Belgiovine C, Mantovani A, Erreni M, Allavena P ( 2016 ) . Non-redundant role of the chemokine receptor CX3CR1 in the anti-inflammatory function of gut macrophages . Immunobiology vol. 222 , ( 2 ) 463 - 472 .

Doni A, D'Amico G, Mantovani A ( 2016 ) . Humoral innate immunity at the crossroad between microbe and matrix recognition: The role of PTX3 in tissue damage . Seminars in Cell and Developmental Biology vol. 61 , 31 - 40 .

Udalova IA, Mantovani A, Feldmann M ( 2016 ) . Macrophage heterogeneity in the context of rheumatoid arthritis . Nature Reviews Rheumatology vol. 12 , ( 8 ) 472 - 485 .

Frazzoli C, Pouokam GB, Orisakwe OE ( 2016 ) . Health risks from lost awareness of cultural behaviours rooted in traditional medicine: An insight in geophagy and mineral intake . The Science of The Total Environment vol. 566 , 1465 - 1471 .

Anselmo A, Riva F, Gentile S, Soldani C, Barbagallo M, Mazzon C, Feruglio F, Polentarutti N et al. ( 2016 ) . Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets . Cardiovascular Research vol. 111 , ( 4 ) 373 - 384 .

Addimanda O, Pulsatelli L, Boiardi L, Assirelli E, Pazzola G, Muratore F, Dolzani P, Versari A et al. ( 2016 ) . AB0051 Angiogenic and Anti-Angiogenic Factors: Biomarkers for Large Vessel Vasculitis? . Annals of the Rheumatic Diseases . vol. 75 ,

Cavalli G, Koenders M, Kim J, Tan AC, Garlanda C, Mantovani A, Dagna L, Joosten L et al. ( 2016 ) . FRI0001 Treating Experimental Arthritis with The Innate Immune Inhibitor IL-37 Reduces Joint and Systemic Inflammation . Annals of the Rheumatic Diseases . vol. 75 ,

Mosbah R, Mokrani N, Mosbahi I, Rouabhi S, Mantovani A ( 2016 ) . Effect of methomyl on the biochemical and reproductive parameters in pregnancy rats: the protective role of Pistacia Lentiscus oil . Endocrine Abstracts

Liguori M, Buracchi C, Pasqualini F, Bergomas F, Pesce S, Mantovani A, Belgiovine C ( 2016 ) . Functional TRAIL receptors in monocytes and tumor-associated macrophages: a possible targeting pathway in the tumor microenvironment . Oncotarget vol. 7 , ( 27 ) 41662 - 41676 .

Magrini E, Mantovani A ( 2016 ) . The Dual Complexity of PTX3 in Health and Disease: A Balancing Act? . Trends in Molecular Medicine vol. 22 , ( 6 ) 497 - 510 .

Molgora M, Barajon I, Mantovani A, Garlanda C ( 2016 ) . Regulatory Role of IL-1R8 in Immunity and Disease . Frontiers in Immunology vol. 7 ,

Jaillon S, Ponzetta A, Magrini E, Barbagallo M, Garlanda C ( 2016 ) . Fluid phase recognition molecules in neutrophil-dependent immune responses . Seminars in Immunology vol. 28 , ( 2 ) 109 - 118 .

Galdiero MR, Bianchi P, Grizzi F, Di Caro G, Basso G, Ponzetta A, Bonavita E, Barbagallo M et al. ( 2016 ) . Occurrence and significance of tumor‐associated neutrophils in patients with colorectal cancer . International Journal of Cancer vol. 139 , ( 2 ) 446 - 456 .

Bonacina F, Barbieri SS, Cutuli L, Amadio P, Doni A, Sironi M, Tartari S, Mantovani A et al. ( 2016 ) . Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation . Biochimica et Biophysica Acta vol. 1862 , ( 6 ) 1182 - 1190 .

Bottazzi B, Inforzato A, Messa M, Barbagallo M, Magrini E ( 2016 ) . The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling . Journal of Hepatology vol. 64 , ( 6 ) 1416 - 1427 .

Massara M, Bonavita O, Mantovani A, Locati M, Bonecchi R ( 2016 ) . Atypical chemokine receptors in cancer: friends or foes? . Journal of Leukocyte Biology vol. 99 , ( 6 ) 927 - 933 .

Mantovani A ( 2016 ) . Reflections on immunological nomenclature: in praise of imperfection . Nature Immunology vol. 17 , ( 3 ) 215 - 216 .

Simon A, Subra J-F, Guilpain P, Jeannin P, Pignon P, Blanchard S, Garo E, Jaillon S et al. ( 2016 ) . Detection of Anti-Pentraxin-3 Autoantibodies in ANCA-Associated Vasculitis . PLOS ONE vol. 11 , ( 1 )

Erreni M, Siddiqui I, Marelli G, Grizzi F, Bianchi P, Morone D, Marchesi F, Celesti G et al. ( 2016 ) . The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by Limiting Tumor Metastatic Dissemination . The Journal of Immunology vol. 196 , ( 2 ) 902 - 914 .

Cappuzzello C, Doni A, Dander E, Pasqualini F, Nebuloni M, Bottazzi B, Mantovani A, Biondi A et al. ( 2016 ) . Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling . Journal of Investigative Dermatology vol. 136 , ( 1 ) 293 - 300 .

Ummenthum K, Peferoen LAN, Finardi A, Baker D, Pryce G, Mantovani A, Bsibsi M, Bottazzi B et al. ( 2015 ) . Pentraxin‐3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease . European Journal of Immunology vol. 46 , ( 3 ) 701 - 711 .

Garlanda C, Jaillon S, Doni A, Bottazzi B ( 2015 ) . PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition . Current Opinion in Immunology vol. 38 , 39 - 44 .

Sica A, Mancino A, Larghi P, Rubino L, Solinas G, Allavena P, Mantovani A ( 2015 ) . Tumor-Associated Macrophages . Encyclopedia of Cancer , Springer Nature

De Paoli P, Ciliberto G, Ferrarini M, Pelicci P, De Lorenzo F, Mantovani A, Musto P, Opocher G et al. ( 2015 ) . Alliance Against Cancer, the network of Italian cancer centers bridging research and care . Journal of Translational Medicine vol. 13 , ( 1 )

Foo S-S, Reading PC, Jaillon S, Mantovani A, Mahalingam S ( 2015 ) . Pentraxins and Collectins: Friend or Foe during Pathogen Invasion? . Trends in Microbiology vol. 23 , ( 12 ) 799 - 811 .

La Rocca C, Tait S, Guerranti C, Busani L, Ciardo F, Bergamasco B, Mancini FR, Bordi G et al. ( 2015 ) . Exposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features . International Journal of Environmental Research and Public Health vol. 12 , ( 10 ) 12426 - 12445 .

Infante M, Allavena P, Garlanda C, Nebuloni M, Morenghi E, Rahal D, Roncalli M, Cavuto S et al. ( 2015 ) . Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients . International Journal of Cancer vol. 138 , ( 4 ) 983 - 991 .

Doni A, Garlanda C, Mantovani A ( 2015 ) . PTX3 orchestrates tissue repair . Oncotarget vol. 6 , ( 31 ) 30435 - 30436 .

Cunha C, Monteiro AA, Oliveira-Coelho A, Kühne J, Rodrigues F, Sasaki SD, Schio SM, Camargo JJ et al. ( 2015 ) . PTX3-Based Genetic Testing for Risk of Aspergillosis After Lung Transplant . Clinical Infectious Diseases vol. 61 , ( 12 ) 1893 - 1894 .

Bonavita E, Mantovani A, Garlanda C ( 2015 ) . PTX3 acts as an extrinsic oncosuppressor . Oncotarget vol. 6 , ( 32 ) 32309 - 32310 .

Di G, Cortese N, Castino GF, Grizzi F, Gavazzi F, Ridolfi C, Capretti G, Mineri R et al. ( 2015 ) . Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy . Gut vol. 65 , ( 10 )

Bachelerie F, Graham GJ, Locati M, Mantovani A, Rot A, Sozzani S ( 2015 ) . An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15 . British Journal of Pharmacology vol. 172 , ( 16 ) 3945 - 3949 .

Bonavita E, Galdiero MR, Jaillon S ( 2015 ) . Chapter Four Phagocytes as Corrupted Policemen in Cancer-Related Inflammation . Advances in Cancer Research vol. 128 , 141 - 171 .

Cardoso AP, Pinto ML, Pinto AT, Pinto MT, Monteiro C, Oliveira MI, Santos SG, Mantovani A ( 2015 ) . Matrix metalloproteases as maestros for the dual role of LPS- and IL-10-stimulated macrophages in cancer cell behaviour . BMC Cancer vol. 15 , ( 1 )

Ramirez GA, Blasi M, Bottazzi B, Valentino S, Tombetti E, Sabbadini MG, Rovere-Querini P, Mantovani A et al. ( 2015 ) . FRI0263 PTX3 and TSG-6 Identify Specific Disease Subsets in Anca-Associated Vasculitides . Annals of the Rheumatic Diseases . vol. 74 , 519 - 520 .

Meliconi R, Dolzani P, Assirelli E, Pulsatelli L, Pipitone N, Muratore F, Pazzola G, Boiardi L et al. ( 2015 ) . FRI0276 Angiogenic and Anti-Angiogenic Factors in Large-Vessel Vasculitides . Annals of the Rheumatic Diseases . vol. 74 , 524 - 525 .

Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I et al. ( 2015 ) . An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode . Journal of Cell Biology vol. 209 , ( 4 )

Isailovic N, Daigo K ( 2015 ) . Interleukin-17 and innate immunity in infections and chronic inflammation . Journal of Autoimmunity vol. 60 , 1 - 11 .

Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Cambieri I, Stravalaci M et al. ( 2015 ) . An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode . Journal of Experimental Medicine vol. 212 , ( 6 ) 905 - 925 .

Di G, Castino GF, Bergomas F, Cortese N, Chiriva-Internati M, Grizzi F, Mantovani A, Marchesi F ( 2015 ) . Tertiary Lymphoid Tissue in the Tumor Microenvironment: From Its Occurrence to Immunotherapeutic Implications . International Reviews of Immunology vol. 34 , ( 2 ) 123 - 133 .

Allavena P, Germano G, Mantovani A ( 2015 ) . Molecular links between inflammation and cancer . Systems Biology of Cancer , Cambridge University Press (CUP)

Proietti I, Frazzoli C ( 2015 ) . Exploiting Nutritional Value of Staple Foods in the World’s Semi-Arid Areas: Risks, Benefits, Challenges and Opportunities of Sorghum . Healthcare vol. 3 , ( 2 ) 172 - 193 .

Bassi N, Del Prete D, Ghirardello A, Gatto M, Ceol M, Zen M, Bettio S, Mantovani A et al. ( 2015 ) . PTX3, Anti-PTX3, and Anti-C1q Autoantibodies in Lupus Glomerulonephritis . Clinical Reviews in Allergy & Immunology vol. 49 , ( 2 ) 217 - 226 .

Bottazzi B, Santini L, Savino S, Giuliani MM, Díez AID, Mancuso G, Beninati C, Sironi M et al. ( 2015 ) . Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant . PLOS ONE vol. 10 , ( 3 )

Mantovani A, Allavena P ( 2015 ) . The interaction of anticancer therapies with tumor-associated macrophages . Journal of Experimental Medicine vol. 212 , ( 4 ) 435 - 445 .

Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW et al. ( 2015 ) . IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction . Nature Immunology vol. 16 , ( 4 ) 354 - 365 .

Foo S-S, Chen W, Taylor A, Sheng K-C, Yu X, Teng T-S, Reading PC, Blanchard H et al. ( 2015 ) . Role of Pentraxin 3 in Shaping Arthritogenic Alphaviral Disease: From Enhanced Viral Replication to Immunomodulation . PLOS Pathogens vol. 11 , ( 2 )

Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M et al. ( 2015 ) . Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8 . Proceedings of the National Academy of Sciences of the United States of America vol. 112 , ( 8 ) 2497 - 2502 .

Bonavita E, Gentile S, Rubino M, Maina V, Papait R, Kunderfranco P, Greco C, Feruglio F et al. ( 2015 ) . PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer . Cell vol. 160 , ( 4 ) 700 - 714 .

Galdiero MR, Mantovani A ( 2015 ) . Chapter 6 Macrophage Plasticity and Polarization Relevance to Biomaterials . Host Response to Biomaterials , Elsevier

Mariotto A, Peretti M, Scirè G, Mantovani A, Zambaldo S, Pani E, Camoglio FS, Giacomello L ( 2014 ) . Trichobezoars in children: therapeutic complications . La Pediatria Medica e Chirurgica vol. 36 , ( 5-6 )

Jaillon S, Bonavita E, Gentile S, Rubino M, Laface I, Garlanda C, Mantovani A ( 2014 ) . The Long Pentraxin PTX3 as a Key Component of Humoral Innate Immunity and a Candidate Diagnostic for Inflammatory Diseases . International Archives of Allergy and Immunology vol. 165 , ( 3 ) 165 - 178 .

Galdiero MR, Mantovani A ( 2014 ) . Tumor-Associated Macrophages in Tumor Progression: From Bench to Bedside . Multi-Targeted Approach to Treatment of Cancer , Springer Nature

Siddiqui I, Mantovani A, Allavena P ( 2014 ) . Adoptive T-Cell Therapy: Optimizing Chemokine Receptor-Mediated Homing of T Cells in Cancer Immunotherapy . Cancer Immunology , Springer Nature

Tombetti E, Di Chio MC, Sartorelli S, Papa M, Salerno A, Bottazzi B, Bozzolo EP, Greco M et al. ( 2014 ) . Systemic pentraxin-3 levels reflect vascular enhancement and progression in Takayasu arteritis . Arthritis Research & Therapy vol. 16 , ( 6 )

Bonecchi R, Savino B, Caronni N, Celesti G, Mantovani A, Locati M ( 2014 ) . Atypical chemokine receptor 2: a brake against Kaposi's sarcoma aggressiveness . OncoImmunology vol. 3 , ( 12 )

Allavena P, Germano G, Belgiovine C, D’Incalci M, Mantovani A ( 2014 ) . Trabectedin . OncoImmunology vol. 2 , ( 6 )

Mauri T, Coppadoro A, Bombino M, Bellani G, Zambelli V, Fornari C, Berra L, Bittner EA et al. ( 2014 ) . Alveolar pentraxin 3 as an early marker of microbiologically confirmed pneumonia: a threshold-finding prospective observational study . Critical Care vol. 18 , ( 5 )

Zampieri N, Mantovani A, Scirè G, Zambaldo S, Zampieri G, Camoglio F ( 2014 ) . PO-0923 Varicocele Treatment In Paediatric Age: Report Of Different Techniques . Archives of Disease in Childhood vol. 99 , ( Suppl 2 )

Zampieri N, Bruno C, Mantovani A, Scirè G, Zambaldo S, Camoglio F ( 2014 ) . PO-0924 Elastosonography Of The Corpus Spongiosum: Comparison Between Normal And Hypospadic Anatomy . Archives of Disease in Childhood vol. 99 , ( Suppl 2 )

Zampieri N, Bruno C, Mantovani A, Zambaldo S, Mariotto A, Peretti M, Scirè G, Camoglio F ( 2014 ) . PS-068 Varicocele And Adolescent: The Role Of Elastosonography In The Evaluation Of Testes . Archives of Disease in Childhood vol. 99 , ( Suppl 2 )

La Rocca C, Tait S, Guerranti C, Busani L, Ciardo F, Bergamasco B, Stecca L, Mancini FR et al. ( 2014 ) . Exposure to Endocrine Disrupters and Nuclear Receptor Gene Expression in Infertile and Fertile Women from Different Italian Areas . International Journal of Environmental Research and Public Health vol. 11 , ( 10 ) 10146 - 10164 .

Bonfiglio R, Camaioni A, Palone F, Bottazzi B, Sironi M, Garlanda C, Salvatori G, Mantovani A et al. ( 2014 ) . Effect of pentraxin 3 on inflammation-induced fetal loss . Reproduction Abstracts

Netea MG, Mantovani A ( 2014 ) . Adaptive Characteristics of Innate Immune Responses in Macrophages . Macrophages: Biology and Role in the Pathology of Diseases , Springer Nature

Galdiero MR, Biswas SK, Mantovani A ( 2014 ) . Polarized Activation of Macrophages . Macrophages: Biology and Role in the Pathology of Diseases , Springer Nature

Bozza S, Campo S, Arseni B, Inforzato A, Ragnar L, Bottazzi B, Mantovani A, Moretti S et al. ( 2014 ) . PTX3 Binds MD-2 and Promotes TRIF-Dependent Immune Protection in Aspergillosis . The Journal of Immunology vol. 193 , ( 5 ) 2340 - 2348 .

Scirè G, Mantovani A, Zampieri N, Guerriero VA, Segala D, Pecori S, Bruno C, Camoglio FS ( 2014 ) . Transumbilical laparoscopic treatment of Congenital Infantile Fibrosarcoma of the Ileum . La Pediatria Medica e Chirurgica vol. 36 , ( 4 )

Brennecke P, Allavena P, Laface I, Mantovani A, Bottazzi B ( 2014 ) . Inflammatory and Innate Immune Cells in Cancer Microenvironment and Progression . Cancer Immunology , Springer Nature

Mantovani A ( 2014 ) . Macrophages, Neutrophils, and Cancer: A Double Edged Sword . New Journal of Science vol. 2014 , ( 1 ) 1 - 14 .

Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA et al. ( 2014 ) . Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines . Immunity vol. 41 , ( 2 ) 339 - 340 .

Mantovani A, Vecchi A, Allavena P ( 2014 ) . Pharmacological modulation of monocytes and macrophages . Current Opinion in Pharmacology vol. 17 , 38 - 44 .

Savino B, Caronni N, Anselmo A, Pasqualini F, Borroni EM, Basso G, Celesti G, Laghi L et al. ( 2014 ) . ERK-Dependent Downregulation of the Atypical Chemokine Receptor D6 Drives Tumor Aggressiveness in Kaposi Sarcoma . Cancer Immunology Research vol. 2 , ( 7 ) 679 - 689 .

Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA et al. ( 2014 ) . Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines . Immunity vol. 41 , ( 1 ) 14 - 20 .

Ramirez GA, Tombetti E, Baldini M, Bottazzi B, Buzio C, Dell'Antonio G, Monno A, Nicastro M et al. ( 2014 ) . AB0045 Plasma and Tissue Expression of PTX3 in Patients with Chronic Periaortitis . Annals of the Rheumatic Diseases . vol. 73 ,

Siddiqui I, Marchesi F, Erreni M, Pesce S ( 2014 ) . Inflammation triggered by oncogenic KRasG12V in pancreatic tumor cells . Pancreatology vol. 14 , ( 3 )

Di G, Castino G, Bergomas F, Cortese N, Grizzi F, Ridolfi C, Gavazzi F, Mantovani A et al. ( 2014 ) . Occurrence of tertiary lymphoid tissue in pancreatic adenocarcinoma . Pancreatology vol. 14 , ( 3 )

Zampieri N, Mantovani A, Scirè G, Camoglio FS ( 2014 ) . Neonatal Surgery for Giant Floating Abdominal Cysts in Females: Clinical and Surgical Management . Journal of Pediatric and Adolescent Gynecology vol. 27 , ( 5 ) 271 - 273 .

Celesti G, Caro GD, Bianchi P, Grizzi F, Basso G, Doni A, Marchesi F, Marra G et al. ( 2013 ) . Abstract A32: Colorectal cancer stroma: Tumor cells in disguise . Cancer Research . vol. 73 , a32 - a32 .

Mantovani A ( 2014 ) . IL-10 and Macrophages Orchestrate Gut Homeostasis . Immunity vol. 40 , ( 5 ) 637 - 639 .

Daigo K, Mantovani A ( 2014 ) . The yin-yang of long pentraxin PTX3 in inflammation and immunity . Immunology Letters vol. 161 , ( 1 ) 38 - 43 .

Mantovani A, Bottazzi B, Doni A, Salvatori G, Jeannin P, Garlanda C ( 2014 ) . Phagocytes Are a Source of the Fluid‐Phase Pattern Recognition Receptor PTX3: Interplay between Cellular and Humoral Innate Immunity . Phagocyte-Pathogen Interactions , American Society for Microbiology

Di G, Bergomas F, Grizzi F, Doni A, Bianchi P, Malesci A, Laghi L, Allavena P et al. ( 2014 ) . Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers . Clinical Cancer Research vol. 20 , ( 8 ) 2147 - 2158 .

Sica A, Invernizzi P, Mantovani A ( 2014 ) . Macrophage plasticity and polarization in liver homeostasis and pathology . Hepatology vol. 59 , ( 5 ) 2034 - 2042 .

Jaillon S, Moalli F, Ragnarsdottir B, Bonavita E, Puthia M, Riva F, Barbati E, Nebuloni M et al. ( 2014 ) . The Humoral Pattern Recognition Molecule PTX3 Is a Key Component of Innate Immunity against Urinary Tract Infection . Immunity vol. 40 , ( 4 ) 621 - 632 .

Bellora F, Castriconi R, Dondero A, Pessino A, Nencioni A, Liggieri G, Moretta L, Mantovani A et al. ( 2014 ) . TLR activation of tumor‐associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells . European Journal of Immunology vol. 44 , ( 6 ) 1814 - 1822 .

Latini R, Gullestad L, Masson S, Nymo SH, Ueland T, Cuccovillo I, Vårdal M, Bottazzi B et al. ( 2014 ) . Pentraxin‐3 in chronic heart failure: the CORONA and GISSI‐HF trials . European Journal of Heart Failure vol. 14 , ( 9 ) 992 - 999 .

Bachelerie F, Graham GJ, Locati M, Mantovani A, Nibbs R, Sozzani S ( 2014 ) . New nomenclature for atypical chemokine receptors . Nature Immunology vol. 15 , ( 3 ) 207 - 208 .

Blok DC, van Lieshout MHP, Hoogendijk AJ, Florquin S, de Boer OJ, Garlanda C, Mantovani A, Veer CV et al. ( 2014 ) . Single Immunoglobulin Interleukin-1 Receptor-Related Molecule Impairs Host Defense during Pneumonia and Sepsis Caused by Streptococcus Pneumoniae . Journal of Innate Immunity vol. 6 , ( 4 ) 542 - 552 .

Cunha C, Aversa F, Lacerda JF, Busca A, Kurzai O, Grube M, Löffler J, Maertens JA et al. ( 2014 ) . Genetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation . The New England Journal of Medicine vol. 370 , ( 5 ) 421 - 432 .

Bottazzi B, Fornasari L, Frangolho A, Giudicatti S, Mantovani A, Marabelli F, Marchesini G, Pellacani P et al. ( 2014 ) . Multiplexed label-free optical biosensor for medical diagnostics . Journal of Biomedical Optics vol. 19 , ( 1 ) 017006 - 017006 .

Anders H-J, Romagnani P, Mantovani A ( 2014 ) . Pathomechanisms: homeostatic chemokines in health, tissue regeneration, and progressive diseases . Trends in Molecular Medicine vol. 20 , ( 3 ) 154 - 165 .

Job ER, Bottazzi B, Short KR, Deng Y-M, Mantovani A, Brooks AG, Reading PC ( 2014 ) . A Single Amino Acid Substitution in the Hemagglutinin of H3N2 Subtype Influenza A Viruses Is Associated with Resistance to the Long Pentraxin PTX3 and Enhanced Virulence in Mice . The Journal of Immunology vol. 192 , ( 1 ) 271 - 281 .

Zampieri N, Scirè G, Mantovani A, Camoglio FS ( 2014 ) . Transumbilical laparoscopic-assisted appendectomy in children: Clinical and surgical outcomes . World Journal of Gastrointestinal Endoscopy vol. 6 , ( 4 ) 101 - 104 .

Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G et al. ( 2013 ) . Selective Activation of Human Dendritic Cells by OM-85 through a NF-kB and MAPK Dependent Pathway . PLOS ONE vol. 8 , ( 12 )

Bellora F, Castriconi R, Dondero A, Carrega P, Mantovani A, Ferlazzo G, Moretta A, Bottino C ( 2013 ) . Human NK cells and NK receptors . Immunology Letters vol. 161 , ( 2 ) 168 - 173 .

Baragetti A, Knoflach M, Cuccovillo I, Grigore L, Casula M, Garlaschelli K, Mantovani A, Wick G et al. ( 2013 ) . Pentraxin 3 (PTX3) plasma levels and carotid intima media thickness progression in the general population . Nutrition Metabolism and Cardiovascular Diseases vol. 24 , ( 5 ) 518 - 523 .

Garlanda C, Dinarello CA ( 2013 ) . The Interleukin-1 Family: Back to the Future . Immunity vol. 39 , ( 6 ) 1003 - 1018 .

Cappuzzello C, Doni A, Dander E, Pasqualini F, Nebuloni M, Bottazzi B, Mantovani A, Biondi A et al. ( 2013 ) . Role Of Long Pentraxin 3 (PTX3) In Wound Closure Induced By Bone Marrow-Derived Mesenchymal Stromal Cells . Blood . vol. 122 ,

Garlanda C, Riva F, Bonavita E, Mantovani A ( 2013 ) . Negative regulatory receptors of the IL-1 family . Seminars in Immunology vol. 25 , ( 6 ) 408 - 415 .

Beghé B, Verduri A, Bottazzi B, Stendardo M, Fucili A, Balduzzi S, Leuzzi C, Papi A et al. ( 2013 ) . Echocardiography, Spirometry, and Systemic Acute-Phase Inflammatory Proteins in Smokers with COPD or CHF: An Observational Study . PLOS ONE vol. 8 , ( 11 )

Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH et al. ( 2013 ) . International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors . Pharmacological Reviews vol. 66 , ( 1 ) 1 - 79 .

Di Caro G, Celesti G, Grizzi F, Bianchi P, Basso G, Marchesi F, Mantovani A, Malesci A et al. ( 2013 ) . Combined low-FOXP3+ and -CD3+tumor infiltrating lymphocytes: a signature of stage II MSS colorectal cancer at high-risk of recurrence . Journal for ImmunoTherapy of Cancer vol. 1 , ( Suppl 1 )

Zampieri N, Castellani R, Mantovani A, Scirè G, Peretti M, Zampieri G, Camoglio FS ( 2013 ) . Thromboses of the pampiniform plexi after subinguinal varicocelectomy . Pediatric Surgery International vol. 30 , ( 4 ) 441 - 444 .

Crisci E, Fraile L, Valentino S, Martínez-Guinó L, Bottazzi B, Mantovani A, Montoya M ( 2013 ) . Immune characterization of long pentraxin 3 in pigs infected with influenza virus . Veterinary Microbiology vol. 168 , ( 1 ) 185 - 192 .

Celesti G, Di Caro G, Bianchi P, Grizzi F, Marchesi F, Basso G, Rahal D, Delconte G et al. ( 2013 ) . Early expression of the fractalkine receptor CX3CR1 in pancreatic carcinogenesis . British Journal of Cancer vol. 109 , ( 9 ) 2424 - 2433 .

Christersdottir Björklund T, Reilly S-J, Gahm C, Bottazzi B, Mantovani A, Tornvall P, Halle M ( 2013 ) . Increased long-term expression of pentraxin 3 in irradiated human arteries and veins compared to internal controls from free tissue transfers . Journal of Translational Medicine vol. 11 , ( 1 )

Hajishengallis G, Mantovani A, Moretta A, Lambris JD ( 2013 ) . Aegean reflections on innate immunity . Nature Immunology vol. 14 , ( 10 ) 1025 - 1029 .

Russell SE, Stefanska AM, Kubica M, Horan RM, Mantovani A, Garlanda C, Fallon PG, Walsh PT ( 2013 ) . Toll IL-1R8/Single Ig IL-1–Related Receptor Regulates Psoriasiform Inflammation through Direct Inhibition of Innate IL-17A Expression by γδ T Cells . The Journal of Immunology vol. 191 , ( 6 ) 3337 - 3346 .

Li S, Hong J, Nold MF, Nold-Petry CA, Azam T, Garlanda C, Bufler P, Kim S-H et al. ( 2013 ) . 163 Recombinant IL-37 inhibits LPS induced inflammation in a SIGIRR- and MAPK-dependent manner . Cytokine . vol. 63 ,

Nold MF, Nold-Petry CA, Lo C, Li S, Rudloff I, Zepp JA, Azam T, Bufler P et al. ( 2013 ) . 187 Interleukin 37 employs the IL-1 family inhibitory receptor SIGIRR and the alpha chain of the IL-18 receptor to suppress innate immunity . Cytokine . vol. 63 ,

Bonavita E, Gentile S, Polentarutti N, Feruglio F, Pasqualini F, Nebuloni M, Jaillon S, Mantovani A et al. ( 2013 ) . 26 Role of the long pentraxin PTX3 in fibrosarcoma development and progression . Cytokine . vol. 63 ,

Doni A, Sironi M, Musso T, Castagnoli C, Gobbi M, Valentino S, Tartari S, Bottazzi B et al. ( 2013 ) . 70 Orchestration of tissue repair by the humoral pattern recognition molecule PTX3: Linking microbe and matrix recognition . Cytokine . vol. 63 ,

Barry J, Loh Z, Collison A, Mazzone S, Lalwani A, Zhang V, Davidson S, Wybacz E et al. ( 2013 ) . Absence of Toll–IL-1 Receptor 8/Single Immunoglobulin IL-1 Receptor–Related Molecule Reduces House Dust Mite–Induced Allergic Airway Inflammation in Mice . American Journal of Respiratory Cell and Molecular Biology vol. 49 , ( 3 )

Jaillon S, Mancuso G, Hamon Y, Beauvillain C, Cotici V, Midiri A, Bottazzi B, Nebuloni M et al. ( 2013 ) . Prototypic Long Pentraxin PTX3 Is Present in Breast Milk, Spreads in Tissues, and Protects Neonate Mice from Pseudomonas aeruginosa Lung Infection . The Journal of Immunology vol. 191 , ( 4 ) 1873 - 1882 .

Jie Y, Doni A, Romani L, Jürgensen HJ, Behrendt N, Mantovani A, Garred P ( 2013 ) . Ficolin-1–PTX3 Complex Formation Promotes Clearance of Altered Self-Cells and Modulates IL-8 Production . The Journal of Immunology vol. 191 , ( 3 ) 1324 - 1333 .

Mantovani A ( 2013 ) . Platelet-macrophage partnership in innate immunity and inflammation . Nature Immunology vol. 14 , ( 8 ) 768 - 770 .

Sozzani S, Bonecchi R, D'Amico G, Luini W, Bernasconi S, Allavena P, Mantovani A ( 2013 ) . Old and new chemokines. Pharmacological regulation of chemokine production and receptor expression: mini-review . Journal of Chemotherapy vol. 10 , ( 2 ) 142 - 145 .

Mantovani A ( 2013 ) . Tumor-Associated Macrophages as a Paradigm of Macrophage Plasticity, Diversity, and Polarization . Arteriosclerosis Thrombosis and Vascular Biology vol. 33 , ( 7 ) 1478 - 1483 .

Galdiero MR, Bonavita E, Barajon I, Garlanda C, Mantovani A, Jaillon S ( 2013 ) . Tumor associated macrophages and neutrophils in cancer . Immunobiology vol. 218 , ( 11 ) 1402 - 1410 .

Inforzato A, Doni A, Barajon I, Leone R, Garlanda C, Bottazzi B, Mantovani A ( 2013 ) . PTX3 as a paradigm for the interaction of pentraxins with the Complement system . Seminars in Immunology vol. 25 , ( 1 ) 79 - 85 .

Ascierto PA, Grimaldi AM, Acquavella N, Borgognoni L, Calabrò L, Cascinelli N, Cesano A, Del Vecchio M et al. ( 2013 ) . Future perspectives in melanoma research. Meeting report from the “Melanoma Bridge. Napoli, December 2nd-4th 2012” . Journal of Translational Medicine vol. 11 , ( 1 )

Celesti G, Di G, Bianchi P, Grizzi F, Basso G, Marchesi F, Doni A, Marra G et al. ( 2013 ) . Presence of Twist1-Positive Neoplastic Cells in the Stroma of Chromosome-Unstable Colorectal Tumors . Gastroenterology vol. 145 , ( 3 ) 647 - 657.e15 .

Del Prete A, Bonecchi R, Vecchi A, Mantovani A, Sozzani S ( 2013 ) . CCRL2, a fringe member of the atypical chemoattractant receptor family . European Journal of Immunology vol. 43 , ( 6 ) 1418 - 1422 .

Locatelli M, Ferrero S, Boneschi FM, Boiocchi L, Zavanone M, Gaini SM, Bello L, Valentino S et al. ( 2013 ) . The long pentraxin PTX3 as a correlate of cancer-related inflammation and prognosis of malignancy in gliomas . Journal of Neuroimmunology vol. 260 , ( 1-2 ) 99 - 106 .

Biswas SK, Allavena P, Mantovani A ( 2013 ) . Tumor-associated macrophages: functional diversity, clinical significance, and open questions . Seminars in Immunopathology vol. 35 , ( 5 ) 585 - 600 .

Bally I, Ancelet S, Moriscot C, Gonnet F, Mantovani A, Daniel R, Schoehn G, Arlaud GJ et al. ( 2013 ) . Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites . Proceedings of the National Academy of Sciences of the United States of America vol. 110 , ( 21 ) 8650 - 8655 .

Cardoso AP, Pinto ML, Pinto AT, Oliveira MI, Pinto MT, Gonçalves R, Relvas JB, Figueiredo C et al. ( 2013 ) . Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y1086, c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity . Oncogene vol. 33 , ( 16 ) 2123 - 2133 .

Nold C, Nold M, Rudloff I, Lo C, Mangan N, Rotter B, Zepp J, Azam T et al. ( 2013 ) . Interleukin 37 employs the IL-1 family orphan receptor SIGIRR and the alpha chain of the IL-18 receptor to inhibit innate immunity (P6293) . The Journal of Immunology . vol. 190 , 184.7 - 184.7 .

Borroni EM, Cancellieri C, Vacchini A, Benureau Y, Lagane B, Bachelerie F, Arenzana-Seisdedos F, Mizuno K et al. ( 2013 ) . β-Arrestin–Dependent Activation of the Cofilin Pathway Is Required for the Scavenging Activity of the Atypical Chemokine Receptor D6 . Science Signaling vol. 6 , ( 273 ) ra30.1 - s3 .

Jaillon S, Galdiero MR, Del Prete D, Cassatella MA, Garlanda C, Mantovani A ( 2013 ) . Neutrophils in innate and adaptive immunity . Seminars in Immunopathology vol. 35 , ( 4 ) 377 - 394 .

Job ER, Bottazzi B, Gilbertson B, Edenborough KM, Brown LE, Mantovani A, Brooks AG, Reading PC ( 2013 ) . Serum Amyloid P Is a Sialylated Glycoprotein Inhibitor of Influenza A Viruses . PLOS ONE vol. 8 , ( 3 )

Mantovani A, Valentino S, Gentile S, Inforzato A ( 2013 ) . The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules . Annals of the New York Academy of Sciences vol. 1285 , ( 1 ) 1 - 14 .

Galdiero MR, Garlanda C, Jaillon S, Marone G, Mantovani A ( 2013 ) . Tumor associated macrophages and neutrophils in tumor progression . Journal of Cellular Physiology vol. 228 , ( 7 ) 1404 - 1412 .

Hamon Y, Jaillon S, Person C, Giniès J-L, Garo E, Bottazzi B, Ghamrawi S, Urban T et al. ( 2013 ) . Proteolytic cleavage of the long pentraxin PTX3 in the airways of cystic fibrosis patients . Innate Immunity vol. 19 , ( 6 ) 611 - 622 .

Pönitz V, Grundt H, Bottazzi B, Cuccovillo I, Mantovani A, Nilsen D ( 2013 ) . THE LONG PENTRAXIN 3 DID NOT PREDICT OUTCOME WITHIN 45 MONTHS FOLLOW-UP IN PATIENTS FOLLOWING A SEVERE MYOCARDIAL INFARCTION . Journal of the American College of Cardiology . vol. 61 ,

Hollan I, Nebuloni M, Bottazzi B, Mikkelsen K, Førre ØT, Almdahl SM, Mantovani A, Fagerland MW et al. ( 2013 ) . Pentraxin 3, a novel cardiovascular biomarker, is expressed in aortic specimens of patients with coronary artery disease with and without rheumatoid arthritis . Cardiovascular Pathology vol. 22 , ( 5 ) 324 - 331 .

Germano G, Frapolli R, Belgiovine C, Anselmo A, Pesce S, Liguori M, Erba E, Uboldi S et al. ( 2013 ) . Role of Macrophage Targeting in the Antitumor Activity of Trabectedin . Cancer Cell vol. 23 , ( 2 ) 249 - 262 .

Suzuki S, Shishido T, Funayama A, Netsu S, Ishino M, Kitahara T, Sasaki T, Katoh S et al. ( 2013 ) . Long Pentraxin PTX3 Exacerbates Pressure Overload–Induced Left Ventricular Dysfunction . PLOS ONE vol. 8 , ( 1 )

Lech M, Römmele C, Gröbmayr R, Susanti HE, Kulkarni OP, Wang S, Gröne H-J, Uhl B et al. ( 2013 ) . Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury . Kidney International vol. 83 , ( 4 ) 647 - 661 .

Martinez FO, Helming L, Milde R, Varin A, Melgert BN, Draijer C, Thomas B, Fabbri M et al. ( 2013 ) . Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences . Blood vol. 121 , ( 9 ) e57 - e69 .

Mantovani A, Galdiero MR, Allavena P, Sica A ( 2013 ) . Chapter 27 Tumor-associated Macrophages in Cancer Growth and Progression . Cancer Immunotherapy , Elsevier

Locati M, Mantovani A, Sica A ( 2013 ) . Chapter Six Macrophage Activation and Polarization as an Adaptive Component of Innate Immunity . Advances in Immunology vol. 120 , 163 - 184 .

Garlanda C, Riva F, Bonavita E, Gentile S, Mantovani A ( 2013 ) . Decoys and Regulatory “Receptors” of the IL-1/Toll-Like Receptor Superfamily . Frontiers in Immunology vol. 4 ,

Bazzan E, Saetta M, Turato G, Borroni EM, Cancellieri C, Baraldo S, Savino B, Calabrese F et al. ( 2013 ) . Expression of the Atypical Chemokine Receptor D6 in Human Alveolar Macrophages in COPD . Chest vol. 143 , ( 1 ) 98 - 106 .

Garlanda C, Mantovani A ( 2013 ) . Ligands and Receptors of the Interleukin-1 Family in Immunity and Disease . Frontiers in Immunology vol. 4 ,

Inforzato A, Reading PC, Barbati E, Bottazzi B, Garlanda C, Mantovani A ( 2013 ) . The “sweet” side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation . Frontiers in Immunology vol. 3 ,

Barbati E, Specchia C, Villella M, Rossi ML, Barlera S, Bottazzi B, Crociati L, d’Arienzo C et al. ( 2012 ) . Influence of Pentraxin 3 (PTX3) Genetic Variants on Myocardial Infarction Risk and PTX3 Plasma Levels . PLOS ONE vol. 7 , ( 12 )

Mantovani A ( 2012 ) . Humoral innate immunity and the acute phase response 1 . The Biomedical & Life Sciences Collection vol. 2012 , ( 12 )

Mantovani A ( 2012 ) . Humoral innate immunity and the acute phase response 2 . The Biomedical & Life Sciences Collection vol. 2012 , ( 12 )

White ES, Mantovani AR ( 2012 ) . Inflammation, wound repair, and fibrosis: reassessing the spectrum of tissue injury and resolution . The Journal of Pathology vol. 229 , ( 2 ) 141 - 144 .

Mantovani A ( 2012 ) . MSCs, Macrophages, and Cancer: A Dangerous Ménage-à-Trois . Cell Stem Cell vol. 11 , ( 6 ) 730 - 732 .

Mantovani A, Biswas SK, Galdiero MR, Sica A, Locati M ( 2012 ) . Macrophage plasticity and polarization in tissue repair and remodelling . The Journal of Pathology vol. 229 , ( 2 ) 176 - 185 .

Riboldi E, Porta C, Morlacchi S, Viola A, Mantovani A, Sica A ( 2012 ) . Hypoxia-mediated regulation of macrophage functions in pathophysiology . International Immunology vol. 25 , ( 2 ) 67 - 75 .

Carnevale D, Fardella V, Mascio G, Cifelli G, Fardella S, Pallante F, Garlanda C, Mantovani A et al. ( 2012 ) . Abstract 19398: Diastolic Dysfunction and Deposition of Fibrosis in Pressure Overloaded Hearts is Dependent on Pentraxin3 . Circulation vol. 126 , ( suppl_21 )

Doni A, Garlanda C, Bottazzi B, Meri S, Garred P, Mantovani A ( 2012 ) . Interactions of the humoral pattern recognition molecule PTX3 with the complement system . Immunobiology vol. 217 , ( 11 ) 1122 - 1128 .

Mantovani A ( 2012 ) . The Interplay between Primary and Secondary Cytokines . Drugs vol. 54 , ( Suppl 1 ) 15 - 23 .

Paroni M, Moalli F, Nebuloni M, Pasqualini F, Bonfield T, Nonis A, Mantovani A, Garlanda C et al. ( 2012 ) . Response of CFTR-Deficient Mice to Long-Term chronic Pseudomonas aeruginosa Infection and PTX3 Therapy . Journal of Infectious Diseases vol. 208 , ( 1 ) 130 - 138 .

Zampieri N, Zamboni C, Scirè G, Mantovani A, Camoglio F ( 2012 ) . 1377 Necrotizing Enterocolitis in Multiple Gestations: Comparison with Singletons . Archives of Disease in Childhood vol. 97 , ( Suppl 2 )

Zampieri N, Laconi F, Scire G, Mantovani A, Camoglio F ( 2012 ) . 1608 The Role of Transthoracic Ultrasounds to Assess Patients with Pectus Excavatum . Archives of Disease in Childhood vol. 97 , ( Suppl 2 )

Zampieri N, Scirè G, Mantovani A, Laconi F, Pietrobelli A, Camoglio F ( 2012 ) . 283 The Role of Peritoneal Drainage in Bell’s Stage 2 of Necrotizinf Enterocolitis . Archives of Disease in Childhood vol. 97 , ( Suppl 2 )

Mantovani A, Scirè G, Camoglio F, Zampieri N ( 2012 ) . 463 Isolated Torsion of Infundibulum of the Right Fallopian Tube in A 12-Year-Old Girl . Archives of Disease in Childhood vol. 97 , ( Suppl 2 )

Basile A, Moschetta M, Ditonno P, Ria R, Marech I, De Luisi A, Berardi S, Frassanito MA et al. ( 2012 ) . Pentraxin 3 (PTX3) inhibits plasma cell/stromal cell cross‐talk in the bone marrow of multiple myeloma patients . The Journal of Pathology vol. 229 , ( 1 ) 87 - 98 .

Bertilaccio MTS, Simonetti G, Dagklis A, Rocchi M, Rodriguez TV, Apollonio B, Mantovani A, Ponzoni M et al. ( 2012 ) . Bertilaccio MT, Simonetti G, Dagklis A, et al. Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models. Blood. 2011;118(3):660–669 . Blood vol. 120 , ( 13 )

Mantovani A ( 2012 ) . I16 The Yin Yang of decoy receptors in tumor progression . Cytokine . vol. 59 ,

Borroni EM, Cancellieri C, Vacchini A, Benureau Y, Lagane B, Bachelerie F, Arenzana-Seisdedos F, Mizuno K et al. ( 2012 ) . P041 G protein-independent signalling by the chemokine scavenger receptor D6 is required for its chemokine scavenging activity . Cytokine . vol. 59 ,

Inforzato A, Sironi M, Petroni F, Bottazzi B, Mantovani A ( 2012 ) . P144 Pathogen recognition by the long pentraxin PTX3: Roles of glycosylation and interplay with complement . Cytokine . vol. 59 ,

Jaillon S, Moalli F, Ragnarsdottir B, Bonavita E, Riva F, Barbati E, Nebuloni M, Valentino S et al. ( 2012 ) . P149 Role of the humoral pattern recognition molecule PTX3 in defence against urinary tract infections . Cytokine . vol. 59 ,

Mantovani A, Locati M, Uguccioni M ( 2012 ) . Chemokines in immunopathology: From dark sides to clinical translation . Immunology Letters vol. 145 , ( 1-2 )

Graham GJ, Locati M, Mantovani A ( 2012 ) . The biochemistry and biology of the atypical chemokine receptors . Immunology Letters vol. 145 , ( 1-2 ) 30 - 38 .

Bellora F, Castriconi R, Doni A, Cantoni C, Moretta L, Mantovani A, Moretta A, Bottino C ( 2012 ) . M‐CSF induces the expression of a membrane‐bound form of IL‐18 in a subset of human monocytes differentiating in vitro toward macrophages . European Journal of Immunology vol. 42 , ( 6 ) 1618 - 1626 .

Celesti G, Di G, Bianchi P, Grizzi F, Rubino L, Basso G, Doni A, Marchesi F et al. ( 2012 ) . 130 TWIST1 Positive Cells in the Stroma of Colorectal Cancer: Tumor Cells in Disguise . Gastroenterology vol. 142 , ( 5 )

Mauri T, Bellani G, Bombino M, Pradella A, Coppadoro A, Berra L, Cuccovillo I, Bittner EA et al. ( 2012 ) . Alveolar Pentraxin 3 (PTX3) Levels And Diagnosis Of Pneumonia In Critically Ill Patients: A Multicenter Study . Conference: C107. PROGRESS IN BIOMARKERS AND DIAGNOSTICS FOR RESPIRATORY INFECTIONSa5250 - a5250 .

Laghi L, Bianchi P, Grizzi F, Di G, Celesti G, Roncalli M, Mantovani A, Malesci A ( 2012 ) . Su1900 Tumor Infiltrating Macrophages as a Potential Predictive Biomarker of Response to 5-FU in Patients With Microsatellite-Stable Colorectal Cancer . Gastroenterology vol. 142 , ( 5 ) s - 531 .

Baldini M, Maugeri N, Ramirez GA, Giacomassi C, Castiglioni A, Prieto‐González S, Corbera‐Bellalta M, Dell'Antonio G et al. ( 2012 ) . Selective up‐regulation of the soluble pattern‐recognition receptor pentraxin 3 and of vascular endothelial growth factor in giant cell arteritis: Relevance for recent optic nerve ischemia . Arthritis & Rheumatism vol. 64 , ( 5 ) 1487 - 1487 .

Mayi TH, Daoudi M, Derudas B, Gross B, Bories G, Wouters K, Brozek J, Caiazzo R et al. ( 2012 ) . Human Adipose Tissue Macrophages Display Activation of Cancer-related Pathways* . Journal of Biological Chemistry vol. 287 , ( 26 ) 21904 - 21913 .

Meda C, Molla F, De Pizzol M, Regano D, Maione F, Capano S, Locati M, Mantovani A et al. ( 2012 ) . Semaphorin 4A Exerts a Proangiogenic Effect by Enhancing Vascular Endothelial Growth Factor-A Expression in Macrophages . The Journal of Immunology vol. 188 , ( 8 ) 4081 - 4092 .

Savino B, Castor MG, Caronni N, Sarukhan A, Anselmo A, Buracchi C, Benvenuti F, Pinho V et al. ( 2012 ) . Control of murine Ly6Chigh monocyte traffic and immunosuppressive activities by atypical chemokine receptor D6 . Blood vol. 119 , ( 22 ) 5250 - 5260 .

Biswas SK, Mantovani A ( 2012 ) . Orchestration of Metabolism by Macrophages . Cell Metabolism vol. 15 , ( 4 ) 432 - 437 .

Mantovani A ( 2012 ) . Pentraxin-3 in COPD: innocent bystander or amplifier? . European Respiratory Journal vol. 39 , ( 4 ) 795 - 796 .

Laghi L, Bianchi P, Grizzi F, Di G, Celesti G, Roncalli M, Mantovani A, Malesci A ( 2012 ) . CS.01.1 TUMOR INFILTRATING MACROPHAGES AS A POTENTIAL PREDICTIVE BIOMARKER OF RESPONSE TO 5-FU IN PATIENTS WITH MICROSATELLITE-STABLE COLORECTAL CANCER . Digestive and Liver Disease vol. 44 ,

Sica A, Mantovani A ( 2012 ) . Macrophage plasticity and polarization: in vivo veritas . Journal of Clinical Investigation vol. 122 , ( 3 ) 787 - 795 .

Bonecchi R, Savino B, Mantovani A, Locati M ( 2012 ) . Targeting Chemokines in Cancer . Current Immunology Reviews vol. 8 , ( 2 ) 161 - 169 .

Baldini M, Maugeri N, Ramirez GA, Giacomassi C, Castiglioni A, Prieto‐González S, Corbera‐Bellalta M, Di Comite G et al. ( 2012 ) . Selective up‐regulation of the soluble pattern‐recognition receptor pentraxin 3 and of vascular endothelial growth factor in giant cell arteritis: Relevance for recent optic nerve ischemia . Arthritis & Rheumatism vol. 64 , ( 3 ) 854 - 865 .

Knoflach M, Kiechl S, Mantovani A, Cuccovillo I, Bottazzi B, Xu Q, Xiao Q, Gasperi A et al. ( 2012 ) . Pentraxin-3 as a Marker of Advanced Atherosclerosis Results from the Bruneck, ARMY and ARFY Studies . PLOS ONE vol. 7 , ( 2 )

Allavena P, Mantovani A ( 2012 ) . Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment . Clinical & Experimental Immunology vol. 167 , ( 2 ) 195 - 205 .

Marchesi F, Grizzi F, Laghi L, Mantovani A, Allavena P ( 2012 ) . Molecular mechanisms of pancreatic cancer dissemination: the role of the chemokine system . Current Pharmaceutical Design vol. 18 , ( 17 ) 2432 - 2438 .

Ferratini M, Ripamonti V, Masson S, Grati P, Racca V, Cuccovillo I, Raimondi E, Capomolla S et al. ( 2012 ) . Pentraxin-3 Predicts Functional Recovery and 1-Year Major Adverse Cardiovascular Events After Rehabilitation of Cardiac Surgery Patients . Journal of Cardiopulmonary Rehabilitation and Prevention vol. 32 , ( 1 ) 17 - 24 .

Riva F, Bonavita E, Barbati E, Muzio M, Mantovani A, Garlanda C ( 2012 ) . TIR8/SIGIRR is an Interleukin-1 Receptor/Toll Like Receptor Family Member with Regulatory Functions in Inflammation and Immunity . Frontiers in Immunology vol. 3 ,

Bergomas F, Grizzi F, Doni A, Pesce S, Laghi L, Allavena P, Mantovani A, Marchesi F ( 2011 ) . Tertiary Intratumor Lymphoid Tissue in Colo-Rectal Cancer . Cancers vol. 4 , ( 1 ) 1 - 10 .

Balkwill FR, Mantovani A ( 2011 ) . Cancer-related inflammation: Common themes and therapeutic opportunities . Seminars in Cancer Biology vol. 22 , ( 1 ) 33 - 40 .

Dolzani P, Assirelli E, Pulsatelli L, Addimanda O, Mancarella L, Peri G, Mantovani A, Facchini A et al. ( 2011 ) . Systemic inflammation and antibodies to citrullinated peptides in hand osteoarthritis . Clinical and Experimental Rheumatology vol. 29 , ( 6 ) 1006 - 1009 .

Maugeri N, Rovere-Querini P, Slavich M, Coppi G, Doni A, Bottazzi B, Garlanda C, Cianflone D et al. ( 2011 ) . Correction: Early and Transient Release of Leukocyte Pentraxin 3 during Acute Myocardial Infarction . The Journal of Immunology vol. 187 , ( 12 ) 6582 - 6582 .

Van den Bossche J, Malissen B, Mantovani A, De Baetselier P, Van Ginderachter JA ( 2011 ) . Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs . Blood vol. 119 , ( 7 ) 1623 - 1633 .

Barbati E, Bottazzi B, Catapano AL, Garlanda C, Latini R, Mantovani A, Norata GD, Valentino S ( 2011 ) . Pentraxins and Atherosclerosis . Inflammation and Atherosclerosis , Springer Nature

Lee JS, Cella M, McDonald KG, Garlanda C, Kennedy GD, Nukaya M, Mantovani A, Kopan R et al. ( 2011 ) . AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch . Nature Immunology vol. 13 , ( 2 ) 144 - 151 .

Pello OM, De Pizzol M, Mirolo M, Soucek L, Zammataro L, Amabile A, Doni A, Nebuloni M et al. ( 2011 ) . Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology . Blood vol. 119 , ( 2 ) 411 - 421 .

Rodriguez TV, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S et al. ( 2011 ) . Role of Toll Interleukin-1 Receptor (IL-1R) 8, a Negative Regulator of IL-1R/Toll-Like Receptor Signaling, in Resistance to Acute Pseudomonas aeruginosa Lung Infection . Infection and Immunity vol. 80 , ( 1 ) 100 - 109 .

Davey MS, Tamassia N, Rossato M, Bazzoni F, Calzetti F, Bruderek K, Sironi M, Zimmer L et al. ( 2011 ) . Failure to detect production of IL-10 by activated human neutrophils . Nature Immunology vol. 12 , ( 11 ) 1017 - 1018 .

Lleo A, Gershwin ME, Mantovani A, Invernizzi P ( 2011 ) . Towards common denominators in primary biliary cirrhosis: The role of IL-12 . Journal of Hepatology vol. 56 , ( 3 ) 731 - 733 .

Porta C, Riboldi E, Totaro MG, Strauss L, Sica A, Mantovani A ( 2011 ) . Macrophages in cancer and infectious diseases: the good and the bad . Immunotherapy vol. 3 , ( 10 ) 1185 - 1202 .

Nold MF, Nold-Petry CA, Zepp JA, Lo C, Garlanda C, Mantovani A, Bufler P, Dinarello CA ( 2011 ) . CS05-3. Interleukin 37 exerts its anti-inflammatory functions by associating with IL-18Rα and SIGIRR . Cytokine . vol. 56 ,

Liguori M, Solinas G, Germano G, Mantovani A, Allavena P ( 2011 ) . Tumor-Associated Macrophages as Incessant Builders and Destroyers of the Cancer Stroma . Cancers vol. 3 , ( 4 ) 3740 - 3761 .

Inforzato A, Bottazzi B, Garlanda C, Valentino S, Mantovani A ( 2011 ) . Pentraxins in Humoral Innate Immunity . Advances in Experimental Medicine and Biology vol. 946 , 1 - 20 .

Locatelli M, Mantovani A ( 2011 ) . Chemokines in Glioma Progression . Molecular Targets of CNS Tumors , IntechOpen

Bosschaerts T, Morias Y, Stijlemans B, Hérin M, Porta C, Sica A, Mantovani A, De Baetselier P et al. ( 2011 ) . IL‐10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF‐κB p50 member in Trypanosoma congolense infection‐resistant C57BL/6 mice . European Journal of Immunology vol. 41 , ( 11 ) 3270 - 3280 .

Sica A, Mantovani A ( 2011 ) . NF-KappaB-Mediated Regulation of Tumour-Associated Macrophages: Mechanisms and Significance . Tumour-Associated Macrophages , Springer Nature

Mantovani A, Germano G, Marchesi F, Locatelli M ( 2011 ) . Cancer‐promoting tumor‐associated macrophages: New vistas and open questions . European Journal of Immunology vol. 41 , ( 9 ) 2522 - 2525 .

Gordon S, Mantovani A ( 2011 ) . Diversity and plasticity of mononuclear phagocytes . European Journal of Immunology vol. 41 , ( 9 ) 2470 - 2472 .

Ma YJ, Doni A, Romani L, Skjoedt MO, Mantovani A, Garred P ( 2011 ) . Binding of Ficolin-1 to the long pentraxin PTX3: Interacting domain and function on apoptotic cells . Molecular Immunology . vol. 48 ,

Mantovani A, Costantini C, Jaillon S ( 2011 ) . Neutrophils in the activation and regulation of innate and adaptive immunity . Nature Reviews Immunology vol. 11 , ( 8 ) 519 - 531 .

Maugeri N, Rovere-Querini P, Slavich M, Coppi G, Doni A, Bottazzi B, Garlanda C, Cianflone D et al. ( 2011 ) . Early and Transient Release of Leukocyte Pentraxin 3 during Acute Myocardial Infarction . The Journal of Immunology vol. 187 , ( 2 ) 970 - 979 .

Germano G, Mantovani A, Allavena P ( 2011 ) . Targeting of the innate immunity/inflammation as complementary anti-tumor therapies . Annals of Medicine vol. 43 , ( 8 ) 581 - 593 .

Lerzo F, Peri G, Doni A, Bocca P, Morandi F, Pistorio A, Carleo AM, Mantovani A et al. ( 2011 ) . Dexamethasone Prophylaxis in Pediatric Open Heart Surgery Is Associated with Increased Blood Long Pentraxin PTX3: Potential Clinical Implications . Journal of Immunology Research vol. 2011 , ( 1 )

Moalli F, Paroni M, Rodriguez TV, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S et al. ( 2011 ) . Correction: The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa . The Journal of Immunology vol. 186 , ( 12 ) 7273 - 7273 .

Bertilaccio MTS, Simonetti G, Dagklis A, Rocchi M, Rodriguez TV, Apollonio B, Mantovani A, Ponzoni M et al. ( 2011 ) . Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models . Blood vol. 118 , ( 3 ) 660 - 669 .

Moalli F, Jaillon S, Inforzato A, Sironi M, Bottazzi B, Mantovani A, Garlanda C ( 2011 ) . Pathogen Recognition by the Long Pentraxin PTX3 . BioMed Research International vol. 2011 , ( 1 )

Lech M, Römmele C, Kulkarni OP, Susanti HE, Migliorini A, Garlanda C, Mantovani A, Anders H-J ( 2011 ) . Lack of the Long Pentraxin PTX3 Promotes Autoimmune Lung Disease but not Glomerulonephritis in Murine Systemic Lupus Erythematosus . PLOS ONE vol. 6 , ( 5 )

Ievoli E, Lindstedt R, Inforzato A, Camaioni A, Palone F, Day AJ, Mantovani A, Salvatori G et al. ( 2011 ) . Implication of the oligomeric state of the N-terminal PTX3 domain in cumulus matrix assembly . Matrix Biology vol. 30 , ( 5-6 ) 330 - 337 .

Gout E, Moriscot C, Doni A, Dumestre-Pérard C, Lacroix M, Pérard J, Schoehn G, Mantovani A et al. ( 2011 ) . M-Ficolin Interacts with the Long Pentraxin PTX3: A Novel Case of Cross-Talk between Soluble Pattern-Recognition Molecules . The Journal of Immunology vol. 186 , ( 10 ) 5815 - 5822 .

Mauri T, Pradella A, Coppadoro A, Confalonieri A, Bellani G, Bombino M, Cuccovillo I, Patroniti N et al. ( 2011 ) . Alveolar Pentraxin 3 (ptx3) Levels To Diagnose Lung Infection In Critically Ill Patients . Conference: B107. BACTERIAL PNEUMONIA: BIOMARKERS, RESISTANT PATHOGENS AND OUTCOMESa3914 - a3914 .

Laghi L, Bianchi P, Grizzi F, Celesti G, Roncalli M, Mantovani A, Malesci A ( 2011 ) . CD3+ Lymphocytes and Cd68+ Macrophages at the Invasive Margin of Deeply Invading (pT3-T4) Colorectal Cancer and Risk of Post-Surgical Metastasis: A Longitudinal Study . Gastroenterology vol. 140 , ( 5 ) s - 826 .

Celesti G, Bianchi P, Grizzi F, Marchesi F, Destro A, Rahal D, Cappello P, Roncalli M et al. ( 2011 ) . Early Switch-on of the Chemotactic Fractalkine Axis and Its Dynamic Variation in Pancreatic Cancer Invasion and Progression . Gastroenterology vol. 140 , ( 5 ) s - 827 .

Moalli F, Paroni M, Rodriguez TV, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S et al. ( 2011 ) . The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa . The Journal of Immunology vol. 186 , ( 9 ) 5425 - 5434 .

Mantovani A ( 2011 ) . Tumor-associated macrophages in cancer-related inflammation . Immunotherapy vol. 3 , ( 4s ) 21 - 22 .

Skuginna V, Lech M, Allam R, Ryu M, Clauss S, Susanti HE, Römmele C, Garlanda C et al. ( 2011 ) . Toll-Like Receptor Signaling and SIGIRR in Renal Fibrosis upon Unilateral Ureteral Obstruction . PLOS ONE vol. 6 , ( 4 )

Cairo G, Recalcati S, Mantovani A, Locati M ( 2011 ) . Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype . Trends in Immunology vol. 32 , ( 6 ) 241 - 247 .

Jala VR, Mathis SP, Bodduluri SR, Maturu P, Krishnan E, Smith ME, Chilton PM, Mitchell TC et al. ( 2011 ) . Abstract 800: Inflammatory chemokines mediate immune surveillance of intestinal cancer . Cancer Research . vol. 71 , 800 - 800 .

Bonecchi R, Locati M, Mantovani A ( 2011 ) . Chemokines and Cancer: A Fatal Attraction . Cancer Cell vol. 19 , ( 4 ) 434 - 435 .

Garlanda C, Bottazzi B, Moalli F, Deban L, Molla F, Latini R, Mantovani A ( 2011 ) . Pentraxins and Atherosclerosis: The Role of PTX3 . Current Pharmaceutical Design vol. 999 , ( 999 ) 1 - 9 .

Inforzato A, Jaillon S, Moalli F, Barbati E, Bonavita E, Bottazzi B, Mantovani A, Garlanda C ( 2011 ) . The long pentraxin PTX3 at the crossroads between innate immunity and tissue remodelling . HLA vol. 77 , ( 4 ) 271 - 282 .

Mantovani A ( 2011 ) . B cells and macrophages in cancer: yin and yang . Nature Medicine vol. 17 , ( 3 ) 285 - 286 .

Laghi L, Bianchi P, Grizzi F, Celesti G, Roncalli M, Mantovani A, Malesci A ( 2011 ) . OC.08.4: CD3+ AND CD68+ IMMUNE CELLS IN PT3-T4 COLORECTAL CANCERS AND RISK OF METACHRONOUS METASTASIS . Digestive and Liver Disease . vol. 43 ,

Mauri T, Pradella A, Confalonieri A, Bellani G, Ferlicca D, Bombino M, Cuccovillo I, Patroniti N et al. ( 2011 ) . Pentraxin 3 levels from bronchoalveolar lavage of critically ill patients predict lung infection . Critical Care vol. 15 , ( Suppl 1 )

Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T et al. ( 2011 ) . Erratum: IL-1 family nomenclature . Nature Immunology vol. 12 , ( 3 ) 271 - 271 .

Allavena P, Chieppa M, Bianchi G, Solinas G, Fabbri M, Laskarin G, Mantovani A ( 2011 ) . Engagement of the Mannose Receptor by Tumoral Mucins Activates an Immune Suppressive Phenotype in Human Tumor‐Associated Macrophages . Journal of Immunology Research vol. 2010 , ( 1 )

Nur E, van Beers EJ, Martina S, Cuccovillo I, Otten H-M, Schnog J-JB, Meijers JCM, Mantovani A et al. ( 2011 ) . Plasma levels of pentraxin-3, an acute phase protein, are increased during sickle cell painful crisis . Blood Cells Molecules and Diseases vol. 46 , ( 3 ) 189 - 194 .

Del Prete A, Allavena P, Santoro G, Fumarulo R, Corsi MM, Mantovani A ( 2011 ) . Molecular pathways in cancer-related inflammation . Biochemia Medica vol. 21 , ( 3 ) 264 - 275 .

Garlanda C, Bottazzi B, Moalli F, Deban L, Molla F, Latini R, Mantovani A ( 2011 ) . Pentraxins and atherosclerosis: the role of PTX3 . Current Pharmaceutical Design vol. 17 , ( 1 ) 38 - 46 .

Barbui T, Carobbio A, Finazzi G, Vannucchi AM, Barosi G, Antonioli E, Guglielmelli P, Pancrazzi A et al. ( 2010 ) . Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3 . Haematologica vol. 96 , ( 2 ) 315 - 318 .

Allavena P, Germano G, Marchesi F, Mantovani A ( 2010 ) . Chemokines in cancer related inflammation . Experimental Cell Research vol. 317 , ( 5 ) 664 - 673 .

Bellora F, Castriconi R, Dondero A, Reggiardo G, Moretta L, Mantovani A, Moretta A, Bottino C ( 2010 ) . The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes . Proceedings of the National Academy of Sciences of the United States of America vol. 107 , ( 50 ) 21659 - 21664 .

Mantovani A ( 2010 ) . The growing diversity and spectrum of action of myeloid‐derived suppressor cells . European Journal of Immunology vol. 40 , ( 12 ) 3317 - 3320 .

Jie Y, Doni A, Skjoedt M-O, Honoré C, Arendrup M, Mantovani A, Garred P ( 2010 ) . Heterocomplexes of Mannose-binding Lectin and the Pentraxins PTX3 or Serum Amyloid P Component Trigger Cross-activation of the Complement System* . Journal of Biological Chemistry vol. 286 , ( 5 ) 3405 - 3417 .

Clemens J, Holmgren J, Kaufmann SHE, Mantovani A ( 2010 ) . Ten years of the Global Alliance for Vaccines and Immunization: challenges and progress . Nature Immunology vol. 11 , ( 12 ) 1069 - 1072 .

Zanier ER, Brandi G, Peri G, Longhi L, Zoerle T, Tettamanti M, Garlanda C, Sigurtà A et al. ( 2010 ) . Cerebrospinal fluid pentraxin 3 early after subarachnoid hemorrhage is associated with vasospasm . Intensive Care Medicine vol. 37 , ( 2 ) 302 - 309 .

Pulsatelli L, Peri G, Macchioni P, Boiardi L, Salvarani C, Cantini F, Mantovani A, Meliconi R ( 2010 ) . Serum levels of long pentraxin PTX3 in patients with polymyalgia rheumatica . Clinical and Experimental Rheumatology vol. 28 , ( 5 ) 756 - 758 .

Masson S, Aleksova A, Favero C, Staszewsky L, Bernardinangeli M, Belvito C, Cioffi G, Sinagra G et al. ( 2010 ) . Predicting atrial fibrillation recurrence with circulating inflammatory markers in patients in sinus rhythm at high risk for atrial fibrillation: data from the GISSI atrial fibrillation trial . Heart vol. 96 , ( 23 )

Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T et al. ( 2010 ) . IL-1 family nomenclature . Nature Immunology vol. 11 , ( 11 ) 973 - 973 .

Mantovani A, Garlanda C, Allavena P, Sica A, Locati M ( 2010 ) . The Yin Yang of Cancer Related Inflammation . Immunologic Signatures of Rejection , Springer Nature

Chiarini M, Sabelli C, Melotti P, Garlanda C, Savoldi G, Mazza C, Padoan R, Plebani A et al. ( 2010 ) . PTX3 genetic variations affect the risk of Pseudomonas aeruginosa airway colonization in cystic fibrosis patients . Genes & Immunity vol. 11 , ( 8 ) 665 - 670 .

Pauwels NS, Bracke KR, Maes T, Van Pottelberge GR, Garlanda C, Mantovani A, Joos GF, Brusselle GG ( 2010 ) . Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner . Respiratory Research vol. 11 , ( 1 )

Assirelli E, Dolzani P, Pulsatelli L, Addimanda O, Mancarella L, Peri G, Mantovani A, Facchini A et al. ( 2010 ) . 118 SYSTEMIC INFLAMMATION AND ANTIBODIES TO CITRULLINATED PEPTIDES IN HAND OSTEOARTHRITIS . Osteoarthritis and Cartilage . vol. 18 ,

Doni A, Maina V, Sironi M, Cuccovillo I, Cambieri I, Musso T, Castagnoli C, Garlanda C et al. ( 2010 ) . PS2-30 PTX3 is expressed in the skin and is regulated by members of TGF-β family . Cytokine . vol. 52 ,

Marchesi F, Martin AP, Furtado GC, Allavena P, Lira SA, Mantovani A ( 2010 ) . PS3-05 The chemokine network in the formation of tertiary lymphoid structures in colorectal cancer . Cytokine . vol. 52 ,

Job ER, Deng Y-M, Tate MD, Bottazzi B, Crouch EC, Dean MM, Mantovani A, Brooks AG et al. ( 2010 ) . Pandemic H1N1 Influenza A Viruses Are Resistant to the Antiviral Activities of Innate Immune Proteins of the Collectin and Pentraxin Superfamilies . The Journal of Immunology vol. 185 , ( 7 ) 4284 - 4291 .

Mantovani A, Garlanda C, Bottazzi B ( 2010 ) . SS9-1 Cytokines in the interplay between cellular and humoral innate immunity: PTX3 as a paradigm . Cytokine . vol. 52 ,

Biswas SK, Mantovani A ( 2010 ) . Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm . Nature Immunology vol. 11 , ( 10 ) 889 - 896 .

Erreni M, Mantovani A, Allavena P ( 2010 ) . Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer . Cancer Microenvironment vol. 4 , ( 2 ) 141 - 154 .

Moalli F, Doni A, Deban L, Zelante T, Zagarella S, Bottazzi B, Romani L, Mantovani A et al. ( 2010 ) . Role of complement and Fcγ receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus . Blood vol. 116 , ( 24 ) 5170 - 5180 .

Erreni M, Solinas G, Brescia P, Osti D, Zunino F, Colombo P, Destro A, Roncalli M et al. ( 2010 ) . Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1 . European Journal of Cancer vol. 46 , ( 18 ) 3383 - 3392 .

Deban L, Jaillon S, Garlanda C, Bottazzi B, Mantovani A ( 2010 ) . Pentraxins in innate immunity: lessons from PTX3 . Cell and Tissue Research vol. 343 , ( 1 ) 237 - 249 .

Drexler SK, Kong P, Inglis J, Williams RO, Garlanda C, Mantovani A, Yazdi AS, Brennan F et al. ( 2010 ) . SIGIRR/TIR‐8 is an inhibitor of toll‐like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis . Arthritis & Rheumatism vol. 62 , ( 8 ) 2249 - 2261 .

Gout E, Doni A, Lacroix M, Arlaud GJ, Mantovani A, Thielens NM ( 2010 ) . M-ficolin interacts with the long-chain pentraxin PTX3. A novel case of crosstalk between pattern recognition proteins? . Molecular Immunology . vol. 47 , 2232 - 2233 .

Jie Y, Doni A, Honoré C, Skjoedt M-O, Arendrup M, Mantovani A, Garred P ( 2010 ) . MBL and PTX3 interaction provokes powerful antifungal activity by communication between the lectin and classical complement pathways via C1q recruitment . Molecular Immunology . vol. 47 ,

Solinas G, Germano G, Mantovani A, Allavena P ( 2010 ) . ChemInform Abstract: Tumor‐Associated Macrophages (TAM) as Major Players of the Cancer‐Related Inflammation . ChemInform vol. 41 , ( 34 ) no - no .

Marchesi F, Locatelli M, Solinas G, Erreni M, Allavena P, Mantovani A ( 2010 ) . Role of CX3CR1/CX3CL1 axis in primary and secondary involvement of the nervous system by cancer . Journal of Neuroimmunology vol. 224 , ( 1-2 ) 39 - 44 .

Otero K, Vecchi A, Hirsch E, Kearley J, Vermi W, Del Prete A, Gonzalvo-Feo S, Garlanda C et al. ( 2010 ) . Nonredundant role of CCRL2 in lung dendritic cell trafficking . Blood vol. 116 , ( 16 ) 2942 - 2949 .

Solinas G, Schiarea S, Liguori M, Fabbri M, Pesce S, Zammataro L, Pasqualini F, Nebuloni M et al. ( 2010 ) . Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility . The Journal of Immunology vol. 185 , ( 1 ) 642 - 652 .

Mantovani A ( 2010 ) . Molecular pathways linking inflammation and cancer . vol. 10 , ( 4 ) 369 - 373 .

Mantovani A ( 2010 ) . Role of inflammatory cells and mediators in tumor invasion and metastasis . Cancer Metastasis Rev vol. 29 , ( 2 )

Norata G, Garlanda C, Mantovani A, Catapano A ( 2010 ) . W5 DEFICIENCY OF THE LONG PENTRAXIN PTX3 PROMOTES VASCULAR INFLAMMATION AND ATHEROSCLEROSIS . Atherosclerosis Plus . vol. 11 ,

Borroni EM, Mantovani A, Locati M, Bonecchi R ( 2010 ) . Chemokine receptors intracellular trafficking . Pharmacology & Therapeutics vol. 127 , ( 1 ) 1 - 8 .

Bassi N, Ghirardello A, Blank M, Zampieri S, Sarzi-Puttini P, Mantovani A, Shoenfeld Y, Doria A ( 2010 ) . IgG anti-pentraxin 3 antibodies in systemic lupus erythematosus . Annals of the Rheumatic Diseases vol. 69 , ( 9 ) 1704 - 1710 .

Pauwels NS, Bracke KR, Maes T, Van Pottelberge GRM, Garlanda C, Mantovani A, Joos GF, Brusselle GG ( 2010 ) . Cigarette Smoke-induced Pentraxin-3 Expression In Lung Endothelial Cells Is Dependent On The IL-1 Pathway . Conference: B34. MECHANISMS OF LUNG RESPONSES TO ENVIRONMENTAL TOXINSa2813 - a2813 .

de la Torre YM, Fabbri M, Jaillon S, Bastone A, Nebuloni M, Vecchi A, Mantovani A, Garlanda C ( 2010 ) . Evolution of the Pentraxin Family: The New Entry PTX4 . The Journal of Immunology vol. 184 , ( 9 ) 5055 - 5064 .

Erreni M, Laghi L, Celesti G, Bianchi P, Grizzi F, Solinas G, Pesce S, Malesci A et al. ( 2010 ) . W1767 Expression and Function of the Chemokine CX3CL1 and Its Receptor Cx3cr1 in Human Colorectal Cancer . Gastroenterology vol. 138 , ( 5 ) s - 736 .

Solinas G, Marchesi F, Garlanda C, Mantovani A, Allavena P ( 2010 ) . Inflammation-mediated promotion of invasion and metastasis . Cancer and Metastasis Reviews vol. 29 , ( 2 ) 243 - 248 .

Danese S, Mantovani A ( 2010 ) . Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin–Yang interplay between inflammation and cancer . Oncogene vol. 29 , ( 23 ) 3313 - 3323 .

Mantovani A ( 2010 ) . Preface . Springer Nature

Mantovani A, Garlanda C, Allavena P ( 2010 ) . Molecular pathways and targets in cancer-related inflammation . Annals of Medicine vol. 42 , ( 3 ) 161 - 170 .

Inforzato A, Baldock C, Jowitt TA, Holmes DF, Lindstedt R, Marcellini M, Rivieccio V, Briggs DC et al. ( 2010 ) . The Angiogenic Inhibitor Long Pentraxin PTX3 Forms an Asymmetric Octamer with Two Binding Sites for FGF2* . Journal of Biological Chemistry vol. 285 , ( 23 ) 17681 - 17692 .

Bonecchi R, Savino B, Borroni EM, Mantovani A, Locati M ( 2010 ) . Chemokine Decoy Receptors: Structure–Function and Biological Properties . Current Topics in Microbiology and Immunology vol. 341 , 15 - 36 .

Nebuloni M, Pasqualini F, Zerbi P, Lauri E, Mantovani A, Vago L, Garlanda C ( 2010 ) . PTX3 expression in the heart tissues of patients with myocardial infarction and infectious myocarditis . Cardiovascular Pathology vol. 20 , ( 1 ) e27 - e35 .

Mantovani A, Garlanda C, Bottazzi B, Molla F, Latini R ( 2010 ) . Pentraxins in Vascular Pathology: The Role of PTX3 . Atherosclerosis , Wiley

Germano G, Frapolli R, Simone M, Tavecchio M, Erba E, Pesce S, Pasqualini F, Grosso F et al. ( 2010 ) . Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells . Cancer Research vol. 70 , ( 6 ) 2235 - 2244 .

Drexler SK, Wales J, Andreakos E, Kong P, Davis A, Garlanda C, Mantovani A, Hussell T et al. ( 2010 ) . Evidence for a DC‐Specific Inhibitory Mechanism that Depends on MyD88 and SIGIRR . Scandinavian Journal of Immunology vol. 71 , ( 6 ) 393 - 402 .

Deban L, Russo RC, Sironi M, Moalli F, Scanziani M, Zambelli V, Cuccovillo I, Bastone A et al. ( 2010 ) . Regulation of leukocyte recruitment by the long pentraxin PTX3 . Nature Immunology vol. 11 , ( 4 ) 328 - 334 .

Balkwill F ( 2010 ) . Cancer and Inflammation: Implications for Pharmacology and Therapeutics . Clinical Pharmacology & Therapeutics vol. 87 , ( 4 ) 401 - 406 .

Bottazzi B, Doni A, Garlanda C, Mantovani A ( 2010 ) . An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm . Annual Review of Immunology vol. 28 , ( 1 ) 157 - 183 .

Coppadoro A, Mauri T, Bellani G, Patroniti N, Cugno M, Grassi A, Iapichino G, Gattinoni L et al. ( 2010 ) . Early persisting elevation of plasma Pentraxin 3 is associated with mortality and with coagulation impairment in severe sepsis and septic shock . Critical Care vol. 14 , ( Suppl 1 )

Locatelli M, Boiocchi L, Ferrero S, Martinelli Boneschi F, Zavanone M, Pesce S, Allavena P, Maria Gaini S et al. ( 2010 ) . Human glioma tumors express high levels of the chemokine receptor CX3CR1 . European Cytokine Network vol. 21 , ( 1 ) 27 - 33 .

Murakami M, Francavilla C, Torselli I, Corada M, Maddaluno L, Sica A, Matteoli G, Iliev ID et al. ( 2010 ) . Inactivation of Junctional Adhesion Molecule-A Enhances Antitumoral Immune Response by Promoting Dendritic Cell and T Lymphocyte Infiltration . Cancer Research vol. 70 , ( 5 ) 1759 - 1765 .

Hollan I, Bottazzi B, Cuccovillo I, Førre ØT, Mikkelsen K, Saatvedt K, Almdahl SM, Mantovani A et al. ( 2010 ) . Increased levels of serum pentraxin 3, a novel cardiovascular biomarker, in patients with inflammatory rheumatic disease . Arthritis Care & Research vol. 62 , ( 3 ) 378 - 385 .

Mantovani A ( 2010 ) . Macrophages, innate immunity and cancer: balance, tolerance, and diversity . Current Opinion in Immunology vol. 22 , ( 2 ) 231 - 237 .

Mantovani A ( 2010 ) . La mala educación of Tumor-Associated Macrophages: Diverse Pathways and New Players . Cancer Cell vol. 17 , ( 2 ) 111 - 112 .

Mauri T, Bellani G, Patroniti N, Coppadoro A, Peri G, Cuccovillo I, Cugno M, Iapichino G et al. ( 2010 ) . Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality . Intensive Care Medicine vol. 36 , ( 4 ) 621 - 629 .

Lech M, Skuginna V, Kulkarni OP, Gong J, Wei T, Stark RW, Garlanda C, Mantovani A et al. ( 2010 ) . Lack of SIGIRR/TIR8 aggravates hydrocarbon oil‐induced lupus nephritis . The Journal of Pathology vol. 220 , ( 5 ) 596 - 607 .

Balkwill F, Mantovani A ( 2010 ) . Foreword . Cytokine & Growth Factor Reviews vol. 21 , ( 1 )

Marchesi F, Piemonti L, Mantovani A, Allavena P ( 2010 ) . Molecular mechanisms of perineural invasion, a forgotten pathway of dissemination and metastasis . Cytokine & Growth Factor Reviews vol. 21 , ( 1 ) 77 - 82 .

Galliera E, Locati M, Mantovani A, Corsi MM ( 2010 ) . Chemokine System: New Inflammatory Markers on the Horizon . European Journal of Inflammation vol. 8 , ( 1 ) 1 - 6 .

Mauri T, Masson S, Pradella A, Bellani G, Coppadoro A, Bombino M, Valentino S, Patroniti N et al. ( 2010 ) . Elevated Plasma and Alveolar Levels of Soluble Receptor for Advanced Glycation Endproducts Are Associated with Severity of Lung Dysfunction in ARDS Patients . The Tohoku Journal of Experimental Medicine vol. 222 , ( 2 )

Mantovani A, Savino B, Locati M, Allavena P ( 2009 ) . The chemokine system in cancer biology and therapy . Cytokine & Growth Factor Reviews vol. 21 , ( 1 ) 27 - 39 .

Colucci S, Taraboletti G, Primo L, Viale A, Roca C, Valdembri D, Geuna M, Pagano M et al. ( 2009 ) . Gorham‐Stout Syndrome: A Monocyte‐Mediated Cytokine Propelled Disease* . Journal of Bone and Mineral Research vol. 21 , ( 2 ) 207 - 218 .

de Kruif MD, Limper M, Sierhuis K, Wagenaar JFP, Spek CA, Garlanda C, Cotena A, Mantovani A et al. ( 2009 ) . PTX3 predicts severe disease in febrile patients at the emergency department . Journal of Infection vol. 60 , ( 2 ) 122 - 127 .

Cattaneo C, Monte S, Algarotti A, Audisio E, Borlenghi E, Bottazzi B, Campiotti L, Cerqui E et al. ( 2009 ) . Caspofungin Primary Antifungal Prophylaxis in Acute Leukemia Patients During Induction Therapy: Results of a Prospective Phase II Multicentric Study (ProfilC Study) . Blood vol. 114 , ( 22 )

Barbui T, Carobbio A, Bottazzi B, Zilio P, Salvi A, Cuccovillo I, Salmoiraghi S, Finazzi G et al. ( 2009 ) . High-Sensitivity C-Reactive Protein (hs-CRP) and Pentraxin 3 (PTX3) Are Increased in Essential Thrombocythemia and Polycythemia Vera . Blood vol. 114 , ( 22 )

Dander E, Cuccovillo I, Vinci P, Bonanomi S, Di Maio L, Lucchini G, Migliavacca M, Perseghin P et al. ( 2009 ) . Pentraxin-3: An Easily Measurable Soluble Factor to Improve Post-Transplant Graft Versus Host Disease Monitoring and Management . Blood vol. 114 , ( 22 )

Sica A, Mantovani A ( 2009 ) . Macrophage fusion cuisine . Blood vol. 114 , ( 21 ) 4609 - 4610 .

Cassatella MA, Locati M, Mantovani A ( 2009 ) . Never Underestimate the Power of a Neutrophil . Immunity vol. 31 , ( 5 ) 698 - 700 .

Norata GD, Garlanda C, Mantovani A, Catapano AL ( 2009 ) . [73] DEFICIENCY OF THE LONG PENTRAXIN PTX3 PROMOTES VASCULAR INFLAMMATION AND ATHEROSCLEROSIS . Nutrition Metabolism and Cardiovascular Diseases vol. 19 , s18 - s19 .

May L, Kuningas M, van Bodegom D, Meij HJ, Frolich M, Slagboom PE, Mantovani A, Westendorp RGJ ( 2009 ) . Genetic Variation in Pentraxin (PTX) 3 Gene Associates with PTX3 Production and Fertility in Women1 . Biology of Reproduction vol. 82 , ( 2 ) 299 - 304 .

Vetrano S, Borroni EM, Sarukhan A, Savino B, Bonecchi R, Correale C, Arena V, Fantini M et al. ( 2009 ) . The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6 . Gut vol. 59 , ( 2 )

Anichini A, Mortarini R, Parmiani G, Alberti S, Mantovani A ( 2009 ) . T‐cell‐receptor engagement and tumor ICAM‐1 up‐regulation are required to by‐pass low susceptibility of melanoma cells to autologous CTL‐mediated lysis . International Journal of Cancer vol. 53 , ( 6 ) 994 - 1001 .

Mantovani A, Locati M ( 2009 ) . Orchestration of macrophage polarization . Blood vol. 114 , ( 15 ) 3135 - 3136 .

Noris M, Cassis P, Azzollini N, Cavinato R, Cugini D, Casiraghi F, Aiello S, Solini S et al. ( 2009 ) . The Toll-IL-1R Member Tir8/SIGIRR Negatively Regulates Adaptive Immunity against Kidney Grafts . The Journal of Immunology vol. 183 , ( 7 ) 4249 - 4260 .

Pello OM, De Pizzol M, Mirolo M, Mantovani A, Locati M ( 2009 ) . c-Myc triggers macrophage alternative activation and controls macrophage activity and survival in tumour . Cytokine . vol. 48 ,

Lech M, Avila-Ferrufino A, Allam R, Segerer S, Khandoga A, Krombach F, Garlanda C, Mantovani A et al. ( 2009 ) . Resident Dendritic Cells Prevent Postischemic Acute Renal Failure by Help of Single Ig IL-1 Receptor-Related Protein . The Journal of Immunology vol. 183 , ( 6 ) 4109 - 4118 .

Solinas G, Germano G, Mantovani A, Allavena P ( 2009 ) . Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation . Journal of Leukocyte Biology vol. 86 , ( 5 ) 1065 - 1073 .

Jie Y, Doni A, Honoré C, Arendrup M, Mantovani A, Garred P ( 2009 ) . Mannose-binding lectin induces opsonin-like activity of PTX3 and SAP in innate defense against Candida albicans . Molecular Immunology . vol. 46 ,

Mantovani A ( 2009 ) . The Yin-Yang of Tumor-Associated Neutrophils . Cancer Cell vol. 16 , ( 3 ) 173 - 174 .

Porta C, Rimoldi M, Raes G, Brys L, Ghezzi P, Di Liberto D, Dieli F, Ghisletti S et al. ( 2009 ) . Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB . Proceedings of the National Academy of Sciences of the United States of America vol. 106 , ( 35 ) 14978 - 14983 .

Garlanda C, Anders H-J, Mantovani A ( 2009 ) . TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization . Trends in Immunology vol. 30 , ( 9 ) 439 - 446 .

Mantovani A, Garlanda C ( 2009 ) . Macrophage Diversity and Polarization in Atherosclerosis . Arteriosclerosis Thrombosis and Vascular Biology vol. 29 , ( 10 ) 1419 - 1423 .

Norata GD, Marchesi P, Pulakazhi Venu VK, Pasqualini F, Anselmo A, Moalli F, Pizzitola I, Garlanda C et al. ( 2009 ) . Deficiency of the Long Pentraxin PTX3 Promotes Vascular Inflammation and Atherosclerosis . Circulation vol. 120 , ( 8 ) 699 - 708 .

Laghi L, Bianchi P, Miranda E, Balladore E, Pacetti V, Grizzi F, Allavena P, Torri V et al. ( 2009 ) . CD3+ cells at the invasive margin of deeply invading (pT3–T4) colorectal cancer and risk of post-surgical metastasis: a longitudinal study . The Lancet Oncology vol. 10 , ( 9 ) 877 - 884 .

Savino B, Borroni EM, Torres NM, Proost P, Struyf S, Mortier A, Mantovani A, Locati M et al. ( 2009 ) . Recognition Versus Adaptive Up-regulation and Degradation of CC Chemokines by the Chemokine Decoy Receptor D6 Are Determined by Their N-terminal Sequence* . Journal of Biological Chemistry vol. 284 , ( 38 ) 26207 - 26215 .

Ma YJ, Doni A, Hummelshøj T, Honoré C, Bastone A, Mantovani A, Thielens NM, Garred P ( 2009 ) . Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition* . Journal of Biological Chemistry vol. 284 , ( 41 ) 28263 - 28275 .

Porta C, Larghi P, Rimoldi M, Totaro MG, Allavena P, Mantovani A, Sica A ( 2009 ) . Cellular and molecular pathways linking inflammation and cancer . Immunobiology vol. 214 , ( 9-10 ) 761 - 777 .

Martìn-Padura I, Metzelaar MJ, Menard S, Mantovani A, Dejana E ( 2009 ) . Enhanced Adhesion of Colon Carcinoma Cells to Thrombin Stimulated Endothelial Cells . Endothelium vol. 1 , ( 1 ) 41 - 45 .

D'aniello EM, Breviario F, Padura IM, Lampugnani MG, Dejana E, Mantovani A, Introna M ( 2009 ) . Interleukin-1 and Tumor Necrosis Factor Induce Transient Expression of an Inhibitor of Nuclear Factor kB in Endothelial Cells . Endothelium vol. 1 , ( 3 ) 161 - 165 .

Dejana E, Ji-Ming W, Mantovani A ( 2009 ) . The Recruitment of Leukocytes and their Interaction with the Vessel Wall: The Role of Interleukin-1 and Tumor Necrosis Factor . Scandinavian Journal of Rheumatology vol. 16 , ( sup66 ) 19 - 25 .

Borroni EM, Bonecchi R, Buracchi C, Savino B, Mantovani A, Locati M ( 2009 ) . Chemokine Decoy Receptors: New Players in Reproductive Immunology . Immunological Investigations vol. 37 , ( 5-6 ) 483 - 497 .

Sozzani S, Mantovani A ( 2009 ) . EMDS Special Issue: Diversity and Plasticity of the Innate Immune Response . Immunobiology vol. 214 , ( 9-10 )

Martini A, Donelli MG, Mantovani A, Pacciarini MA, Fogar-Ottaviano E, Morasca L, Garattini S, Spreafico F ( 2009 ) . Antineoplastic Activity and Pharmacokinetics of Adriamycin and Daunomycin in Tumor Bearing Mice . Oncology vol. 34 , ( 4 ) 173 - 178 .

Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A ( 2009 ) . Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability . Carcinogenesis vol. 30 , ( 7 ) 1073 - 1081 .

Vetrano S, Borroni EM, Bonecchi R, Correale C, Sarukhan A, Arena V, Fantini MC, Roncalli M et al. ( 2009 ) . 365 The Lymphatic System Controls Intestinal Inflammation and Inflammation-Associated Colon Cancer Through the Chemokine Decoy Receptor D6 . Gastroenterology vol. 136 , ( 5 ) a - 59 .

Erroi A, Specchia G, Liso V, Colotta F, Bersani L, Polentarutti N, Zhen‐Guo C, Allavena P et al. ( 2009 ) . Interleukin‐1 and tumor necrosis factor production in acute non‐lymphoid leukemia . European Journal Of Haematology vol. 42 , ( 1 ) 16 - 23 .

Bassan R, Introna M, Rambaldi A, Viero P, Chisesi T, Mantovani A, Barbui T ( 2009 ) . Large granular lymphocyte/natural killer cell proliferative disease: Clinical and laboratory heterogeneity . European Journal Of Haematology vol. 37 , ( 2 ) 91 - 96 .

Maina V, Cotena A, Doni A, Nebuloni M, Pasqualini F, Milner CM, Day AJ, Mantovani A et al. ( 2009 ) . Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6 . Journal of Leukocyte Biology vol. 86 , ( 1 ) 123 - 132 .

Wagenaar JFP, Goris MGA, Gasem MH, Isbandrio B, Moalli F, Mantovani A, Boer KR, Hartskeerl RA et al. ( 2009 ) . Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis . Journal of Infection vol. 58 , ( 6 ) 425 - 432 .

Mauri T, Bellani G, Patroniti N, Coppadoro A, Pradella A, Gattinoni L, Mantovani A, Pesenti A ( 2009 ) . Early Pentraxin 3 (PTX3) Elevation Is Associated with Severity and Outcome of Severe Sepsis and Septic Shock . Conference: C56. SEPSIS: FROM BENCH TO THE BEDSIDE

Bazzoni F, Rossato M, Fabbri M, Gaudiosi D, Mirolo M, Mori L, Tamassia N, Mantovani A et al. ( 2009 ) . Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals . Proceedings of the National Academy of Sciences of the United States of America vol. 106 , ( 13 ) 5282 - 5287 .

Riva F, Polentarutti N, Tribbioli G, Mantovani A, Garlanda C, Turin L ( 2009 ) . The expression pattern of TIR8 is conserved among vertebrates . Veterinary Immunology and Immunopathology vol. 131 , ( 1-2 ) 44 - 49 .

Souza DG, Amaral FA, Fagundes CT, Coelho FM, Arantes RME, Sousa LP, Matzuk MM, Garlanda C et al. ( 2009 ) . The Long Pentraxin PTX3 Is Crucial for Tissue Inflammation after Intestinal Ischemia and Reperfusion in Mice . American Journal Of Pathology vol. 174 , ( 4 ) 1309 - 1318 .

Deban L, Bottazzi B, Garlanda C, de la Torre YM, Mantovani A ( 2009 ) . Pentraxins: Multifunctional proteins at the interface of innate immunity and inflammation . BioFactors vol. 35 , ( 2 ) 138 - 145 .

Borroni EM, Bonecchi R, Mantovani A, Locati M ( 2009 ) . Chemoattractant Receptors and Leukocyte Recruitment: More Than Cell Migration . Science Signaling vol. 2 , ( 59 )

Mantovani A, Sica A, Allavena P, Garlanda C, Locati M ( 2009 ) . Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation . Human Immunology vol. 70 , ( 5 ) 325 - 330 .

Augusto J-F, Onno C, Blanchard S, Dubuquoi S, Mantovani A, Chevailler A, Jeannin P, Subra J-F ( 2009 ) . Detection of anti-PTX3 autoantibodies in systemic lupus erythematosus . Rheumatology vol. 48 , ( 4 ) 442 - 444 .

Riboldi E, Frascaroli G, Transidico P, Luini W, Bernasconi S, Mancini F, Guglielmotti A, Milanese C et al. ( 2009 ) . Benzydamine inhibits monocyte migration and MAPK activation induced by chemotactic agonists . British Journal of Pharmacology vol. 140 , ( 2 ) 377 - 383 .

Vetrano S, Borroni EM, Bonecchi R, Correale C, Sarukhan A, Vincenzo A, Fantini M, Roncalli M et al. ( 2009 ) . 4 - The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6 . Journal of Crohn's and Colitis vol. 3 , ( 1 ) s4 - s4 .

Borroni EM, Buracchi C, Savino B, Pasqualini F, Russo RC, Nebuloni M, Bonecchi R, Mantovani A et al. ( 2009 ) . Chapter 11 Role of the Chemokine Scavenger Receptor D6 in Balancing Inflammation and Immune Activation . Methods in Enzymology vol. 460 , ( Nat. Rev. Immunol.62006 ) 231 - 243 .

Erreni M, Bianchi P, Laghi L, Mirolo M, Fabbri M, Locati M, Mantovani A, Allavena P ( 2009 ) . Chapter 5 Expression of Chemokines and Chemokine Receptors in Human Colon Cancer . Methods in Enzymology vol. 460 , 105 - 121 .

Bonecchi R, Galliera E, Borroni EM, Corsi MM, Locati M, Mantovani A ( 2009 ) . Chemokines and chemokine receptors: an overview . Frontiers in Bioscience-Landmark vol. 14 , ( 2 ) 540 - 551 .

Turci R, Minoia C, Leoni E, Sturchio E, Boccia P, Meconi C, Zanellato M, Signorini S et al. ( 2009 ) . PCDD: polychlorodibenzo-4-dioxin . Giornale italiano di Medicina del lavoro ed Ergonomia vol. 31 , ( 4 ) 325 - 370 .

Sprong T, Peri G, Neeleman C, Mantovani A, Signorini S, van der Meer JWM, van Deuren M ( 2009 ) . PENTRAXIN 3 AND C-REACTIVE PROTEIN IN SEVERE MENINGOCOCCAL DISEASE . Shock vol. 31 , ( 1 ) 28 - 32 .

Agrawal A, Singh PP, Bottazzi B, Garlanda C, Mantovani A ( 2009 ) . Pattern Recognition by Pentraxins . Advances in Experimental Medicine and Biology vol. 653 , 98 - 116 .

Sica A, Mancino A, Larghi P, Rubino L, Solinas G, Allavena P, Mantovani A ( 2009 ) . Tumor-Associated Macrophages . Encyclopedia of Cancer , Springer Nature

Mantovani A ( 2008 ) . Inflaming metastasis . Nature vol. 457 , ( 7225 ) 36 - 37 .

Bottazzi B, Garlanda C, Cotena A, Moalli F, Jaillon S, Deban L, Mantovani A ( 2008 ) . The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity . Immunological Reviews vol. 227 , ( 1 ) 9 - 18 .

Deban L, Jarva H, Lehtinen MJ, Bottazzi B, Bastone A, Doni A, Jokiranta TS, Mantovani A et al. ( 2008 ) . Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation . The Journal of Immunology vol. 181 , ( 12 ) 8433 - 8440 .

Jaillon S, Jeannin P, Hamon Y, Frémaux I, Doni A, Bottazzi B, Blanchard S, Subra J-F et al. ( 2008 ) . Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages . Cell Death & Differentiation vol. 16 , ( 3 ) 465 - 474 .

Biagi E, Col M, Migliavacca M, Dell'Oro M, Silvestri D, Montanelli A, Peri G, Mantovani A et al. ( 2008 ) . PTX3 as a Potential Novel Tool for the Diagnosis and Monitoring of Pulmonary Fungal Infections in Immuno-compromised Pediatric Patients . Journal of Pediatric Hematology/Oncology vol. 30 , ( 12 ) 881 - 885 .

Mantovani A ( 2008 ) . From phagocyte diversity and activation to probiotics: Back to Metchnikoff . European Journal of Immunology vol. 38 , ( 12 ) 3269 - 3273 .

Marchesi F, Piemonti L, Fedele G, Destro A, Roncalli M, Albarello L, Doglioni C, Anselmo A et al. ( 2008 ) . The Chemokine Receptor CX3CR1 Is Involved in the Neural Tropism and Malignant Behavior of Pancreatic Ductal Adenocarcinoma . Cancer Research vol. 68 , ( 21 ) 9060 - 9069 .

Mantovani A, Sozzani S, Locati M, Schioppa T, Saccani A, Allavena P, Sica A ( 2008 ) . Infiltration of Tumours by Macrophages and Dendritic Cells: Tumour‐Associated Macrophages as a Paradigm for Polarized M2 Mononuclear Phagocytes . Novartis Foundation Symposia vol. 256 , 137 - 148 .

Mantovani A, Muzio M, Garlanda C, Sozzani S, Allavena P ( 2008 ) . Macrophage Control of Inflammation: Negative Pathways of Regulation of Inflammatory Cytokines . Novartis Foundation Symposia vol. 234 , 120 - 135 .

Garlanda C, Bottazzi B, Salvatori G, De Santis R, Cotena A, Deban L, Maina V, Moalli F et al. ( 2008 ) . Pentraxins in Innate Immunity and Inflammation . Novartis Foundation Symposia vol. 279 , 80 - 91 .

Walter S, Govoni D, Bottazzi B, Mantovani A ( 2008 ) . The Role of Macrophages in the Regulation of Primary Tumor Growth . Pathobiology vol. 59 , ( 4 ) 239 - 242 .

Mantovani A, Frazzoli C ( 2008 ) . Risk assessment of endocrine-active compounds in feeds . The Veterinary Journal vol. 182 , ( 3 ) 392 - 401 .

Jie Y, Doni A, Honoré C, Mantovani A, Thielens NM, Garred P ( 2008 ) . Biochemical and functional characterisation of the interaction between pentraxin 3 and the ficolins . Molecular Immunology . vol. 45 ,

Colotta F, Bersani L, Polentarutti N, Peri G, Mantovani A ( 2008 ) . Effects of Inactivated Streptococci (OK-432) on macrophage functions in Mice . Immunopharmacology and Immunotoxicology vol. 7 , ( 4 ) 437 - 449 .

Allavena P, Peccatori F, Maggioni D, Pirovano P, Mantovani A ( 2008 ) . Killing of Tumor Cells with Pleiotropic Drug Resistance by OK432-Activated Effector Cells . Immunopharmacology and Immunotoxicology vol. 11 , ( 2-3 ) 257 - 268 .

Zampieri N, Mantovani A, Ottolenghi A, Camoglio FS ( 2008 ) . Testicular Catch-up Growth After Varicocelectomy: Does Surgical Technique Make a Difference? . Urology vol. 73 , ( 2 ) 289 - 292 .

Mirolo M, Fabbri M, Sironi M, Vecchi A, Guglielmotti A, Mangano G, Biondi G, Locati M et al. ( 2008 ) . Impact of the anti-inflammatory agent bindarit on the chemokinome: selective inhibition of the monocyte chemotactic proteins . European Cytokine Network vol. 19 , ( 3 ) 119 - 122 .

Porta C, Rimoldi M, Mantovani A, Sica A ( 2008 ) . 166 p50 NF-κB overexpression in tumor associated macrophages inhibits M1 inflammatory responses and antitumor resistance . Cytokine . vol. 43 , 274 - 275 .

Maina V, Doni A, Garlanda C, Mantovani A ( 2008 ) . 196 Deficiency of the soluble pattern recognition receptor Pentraxin-3 increases susceptibility to tumor growth and metastasis . Cytokine . vol. 43 ,

Mantovani A ( 2008 ) . PL-8 Molecular pathways linking inflammation and cancer . Cytokine . vol. 43 ,

Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders H-J ( 2008 ) . Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens . Journal of Experimental Medicine vol. 205 , ( 9 ) 2179 - 2179 .

Doni A, Mantovani G, Porta C, Tuckermann J, Reichardt HM, Kleiman A, Sironi M, Rubino L et al. ( 2008 ) . Cell-specific Regulation of PTX3 by Glucocorticoid Hormones in Hematopoietic and Nonhematopoietic Cells* . Journal of Biological Chemistry vol. 283 , ( 44 ) 29983 - 29992 .

Germano G, Allavena P, Mantovani A ( 2008 ) . Cytokines as a key component of cancer-related inflammation . Cytokine vol. 43 , ( 3 ) 374 - 379 .

Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen I-H, Sozzani S, Austyn JM et al. ( 2008 ) . Divergent effects of hypoxia on dendritic cell functions . Blood vol. 112 , ( 9 ) 3723 - 3734 .

Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M et al. ( 2008 ) . Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection . Journal of Experimental Medicine vol. 205 , ( 9 ) 2075 - 2084 .

Wan H, van Helden-Meeuwsen CG, Garlanda C, Leijten LME, Maina V, Khan NA, Drexhage HA, Mantovani A et al. ( 2008 ) . Chorionic gonadotropin up-regulates long pentraxin 3 expression in myeloid cells . Journal of Leukocyte Biology vol. 84 , ( 5 ) 1346 - 1352 .

Mauri T, Coppadoro A, Bellani G, Bombino M, Patroniti N, Peri G, Mantovani A, Pesenti A ( 2008 ) . Pentraxin 3 in acute respiratory distress syndrome: An early marker of severity* . Critical Care Medicine vol. 36 , ( 8 ) 2302 - 2308 .

Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders H-J ( 2008 ) . Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens . Journal of Experimental Medicine vol. 205 , ( 8 ) 1879 - 1888 .

Mantovani A, Locati M ( 2008 ) . Housekeeping by chemokine scavenging . Blood vol. 112 , ( 2 ) 215 - 216 .

Mantovani A, Maranghi F, La Rocca C, Tiboni GM ( 2008 ) . The role of toxicology to characterize biomarkers for agrochemicals with potential endocrine activities . Reproductive Toxicology vol. 26 , ( 1 ) 1 - 7 .

Mantovani A, Allavena P, Sica A ( 2008 ) . Cancer-related inflammation . Nature vol. 454 , ( 7203 ) 436 - 444 .

Galliera E, Locati M, Mantovani A, Corsi MM ( 2008 ) . Chemokines and Bone Remodeling . International Journal of Immunopathology and Pharmacology vol. 21 , ( 3 ) 485 - 491 .

Solinas G, Marchesi F, Fabbri M, Schiarea S, Chiabrando C, Mantovani A, Allavena P ( 2008 ) . Tumour-derived high molecular weight M-CSF induces monocyte differentiation into M2- polarized macrophages . European Journal of Cancer Supplements . vol. 6 ,

Manfredi AA, Rovere-Querini P, Bottazzi B, Garlanda C, Mantovani A ( 2008 ) . Pentraxins, humoral innate immunity and tissue injury . Current Opinion in Immunology vol. 20 , ( 5 ) 538 - 544 .

Mantovani A, Pierotti MA ( 2008 ) . Cancer and inflammation: A complex relationship . Cancer Letters vol. 267 , ( 2 ) 180 - 181 .

Bonecchi R, Borroni EM, Savino B, Buracchi C, Mantovani A, Locati M ( 2008 ) . Non-signaling chemokine receptors: Mechanism of action and role in vivo . Journal of Neuroimmunology vol. 198 , ( 1-2 ) 14 - 19 .

Galliera E, Corsi MM, Bonecchi R, Locati M, Mantovani A ( 2008 ) . Chemokines as pharmacological targets . Mini-Reviews in Medicinal Chemistry vol. 8 , ( 7 ) 638 - 646 .

Alberti L, Gilardini L, Zulian A, Micheletto G, Peri G, Doni A, Mantovani A, Invitti C ( 2008 ) . Expression of long pentraxin PTX3 in human adipose tissue and its relation with cardiovascular risk factors . Atherosclerosis vol. 202 , ( 2 ) 455 - 460 .

Bonecchi R, Borroni EM, Anselmo A, Doni A, Savino B, Mirolo M, Fabbri M, Jala VR et al. ( 2008 ) . Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation . Blood vol. 112 , ( 3 ) 493 - 503 .

Sica A, Allavena P, Mantovani A ( 2008 ) . Cancer related inflammation: The macrophage connection . Cancer Letters vol. 267 , ( 2 ) 204 - 215 .

Allegretti M, Bertini R, Bizzarri C, Beccari A, Mantovani A, Locati M ( 2008 ) . Allosteric inhibitors of chemoattractant receptors: opportunities and pitfalls . Trends in Pharmacological Sciences vol. 29 , ( 6 ) 280 - 286 .

Laškarin G, Redžović A, Rubeša Ž, Mantovani A, Allavena P, Haller H, Vlastelić I, Rukavina D ( 2008 ) . ORIGINAL ARTICLE: Decidual Natural Killer Cell Tuning by Autologous Dendritic Cells . American Journal Of Reproductive Immunology vol. 59 , ( 5 ) 433 - 445 .

Miranda E, Balladore E, Bianchi PP, Mantovani A, Malesci A, Roncalli M, Laghi L ( 2008 ) . 39 Low-Density of CD3+ Cells At the Invasion Front and Increased Risk of Liver Metastases Development in Microsatellite-Stable Colorectal Cancer Patients . Gastroenterology vol. 134 , ( 4 )

Vetrano S, Borroni E, Bonecchi R, Correale C, Arena V, Fantini MC, Malesci A, Vecchi A et al. ( 2008 ) . 401 The Atypical Chemokine Receptor D6 Controls Intestinal Inflammation and Inflammation-Associated Colon Cancer . Gastroenterology vol. 134 , ( 4 ) a - 55 .

Laghi L, Bianchi PP, Marchesi F, Allavena P, Montorsi M, Mantovani A, Malesci A ( 2008 ) . M2036 Early Fractalkine Receptor (CX3CR1) Switch-On in Pancreatic Ductal Adenocarcinoma Is Associated with Local Neural Invasion . Gastroenterology vol. 134 , ( 4 ) a - 455 .

Sica A, Larghi P, Mancino A, Rubino L, Porta C, Totaro MG, Rimoldi M, Biswas SK et al. ( 2008 ) . Macrophage polarization in tumour progression . Seminars in Cancer Biology vol. 18 , ( 5 ) 349 - 355 .

Otero K, Riboldi E, Del Prete A, Vecchi A, Facchetti F, Mantovani A, Sozzani S ( 2008 ) . Multiple Pathways to Control DC Migration . Handbook of Dendritic Cells , Wiley

Allavena P, Bottazzi B, Doni A, Romani L, Garlanda C, Mantovani A ( 2008 ) . Production of the Long Pentraxin PTX3 by Myeloid Dendritic Cells: Linking Cellular and Humoral Innate Immunity . Handbook of Dendritic Cells , Wiley

Allavena P, Sica A, Garlanda C, Mantovani A ( 2008 ) . The Yin‐Yang of tumor‐associated macrophages in neoplastic progression and immune surveillance . Immunological Reviews vol. 222 , ( 1 ) 155 - 161 .

Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D’Angelo C, Giovannini G, Garlanda C et al. ( 2008 ) . Lack of Toll IL-1R8 Exacerbates Th17 Cell Responses in Fungal Infection . The Journal of Immunology vol. 180 , ( 6 ) 4022 - 4031 .

Zanier E, Peri G, Brandi G, Longhi L, Tettamanti M, Garlanda C, Mantovani A, De Simoni M et al. ( 2008 ) . Pentraxin 3 as a marker of vasospasm following subarachnoid hemorrhage . Critical Care vol. 12 , ( Suppl 2 )

Zanella A, Brovelli A, Mantovani A, Izzo C, Rebulla P, Balduini C ( 2008 ) . Membrane Abnormalities of Pyruvate Kinase Deficient Red Cells . British Journal of Haematology vol. 42 , ( 1 ) 101 - 108 .

Rambaldi A, Bettoni S, Rossi V, Tini M, Giudici G, Rizzo V, Bassan R, Mantovani A et al. ( 2008 ) . Transcriptional and post‐transcriptional regulation of IL‐1β, IL‐6 and TNF‐α genes in chronic lymphocytic leukaemia . British Journal of Haematology vol. 83 , ( 2 ) 204 - 211 .

Allavena P, Garlanda C, Borrello MG, Sica A, Mantovani A ( 2008 ) . Pathways connecting inflammation and cancer . Current Opinion in Genetics & Development vol. 18 , ( 1 ) 3 - 10 .

Reading PC, Bozza S, Gilbertson B, Tate M, Moretti S, Job ER, Crouch EC, Brooks AG et al. ( 2008 ) . Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses . The Journal of Immunology vol. 180 , ( 5 ) 3391 - 3398 .

Vetrano S, Correale C, Borroni E, Bonecchi R, Arena V, Fantini M, Malesci A, Vecchi A et al. ( 2008 ) . OC1.08.1 THE ATYPICAL CHEMOKINE RECEPTOR D6 CONTROLS INTESTINAL INFLAMMATION AND INFLAMMATION-ASSOCIATED COLON CANCER . Digestive and Liver Disease . vol. 40 , s24 - s25 .

Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong ME, Garlanda C, Mantovani A et al. ( 2008 ) . IL‐1F5 mediates anti‐inflammatory activity in the brain through induction of IL‐4 following interaction with SIGIRR/TIR8 . Journal of Neurochemistry vol. 105 , ( 5 ) 1960 - 1969 .

Mantovani A, Romero P, Palucka AK, Marincola FM ( 2008 ) . Tumour immunity: effector response to tumour and role of the microenvironment . The Lancet vol. 371 , ( 9614 ) 771 - 783 .

Salio M, Chimenti S, De Angelis N, Molla F, Maina V, Nebuloni M, Pasqualini F, Latini R et al. ( 2008 ) . Cardioprotective Function of the Long Pentraxin PTX3 in Acute Myocardial Infarction . Circulation vol. 117 , ( 8 ) 1055 - 1064 .

Inforzato A, Rivieccio V, Morreale AP, Bastone A, Salustri A, Scarchilli L, Verdoliva A, Vincenti S et al. ( 2008 ) . Structural Characterization of PTX3 Disulfide Bond Network and Its Multimeric Status in Cumulus Matrix Organization* . Journal of Biological Chemistry vol. 283 , ( 15 ) 10147 - 10161 .

Norata GD, Marchesi P, Pirillo A, Uboldi P, Chiesa G, Maina V, Garlanda C, Mantovani A et al. ( 2008 ) . Long Pentraxin 3, a Key Component of Innate Immunity, Is Modulated by High-Density Lipoproteins in Endothelial Cells . Arteriosclerosis Thrombosis and Vascular Biology vol. 28 , ( 5 ) 925 - 931 .

Mantovani A, Marchesi F, Porta C, Allavena P, Sica A ( 2008 ) . Linking Inflammation Reactions to Cancer: Novel Targets for Therapeutic Strategies . Advances in Experimental Medicine and Biology vol. 610 , 112 - 127 .

Martinez FO, Sica A, Mantovani A, Locati M ( 2008 ) . Macrophage activation and polarization . Frontiers in Bioscience-Landmark vol. 13 , ( 13 ) 453 - 461 .

Colotta F, Mantovani A ( 2008 ) . Targeted therapies in cancer: myth or reality? Introduction . vol. 610 , v - vi .

Doni A, Paffoni A, Nebuloni M, Ragni G, Pasqualini F, Valentino S, Bonetti S, Mantovani A et al. ( 2007 ) . The long pentraxin 3 is a soluble and cell‐associated component of the human semen . International Journal of Andrology vol. 32 , ( 3 ) 255 - 264 .

Sadorge C, Ndiaye A, Beveridge N, Frazer S, Giemza R, Jolly N, Johnson J, Liddy H et al. ( 2007 ) . Phase 1 clinical trial of live attenuated Shigella dysenteriae type-1 ΔicsA Δent Δfep ΔstxA:HgR oral vaccine SC599 in healthy human adult volunteers . Vaccine vol. 26 , ( 7 ) 978 - 987 .

Cotena A, Maina V, Sironi M, Bottazzi B, Jeannin P, Vecchi A, Corvaia N, Daha MR et al. ( 2007 ) . Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3 . The Journal of Immunology vol. 179 , ( 9 ) 6311 - 6317 .

Allavena P, Sica A, Solinas G, Porta C, Mantovani A ( 2007 ) . The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages . Critical Reviews in Oncology/Hematology vol. 66 , ( 1 ) 1 - 9 .

Balkwill F, Charles KA, Mantovani A ( 2007 ) . The Links between Inflammation and Cancer . The Cancer Handbook , Wiley

Bowdish DME, Loffredo MS, Mukhopadhyay S, Mantovani A, Gordon S ( 2007 ) . Macrophage receptors implicated in the “adaptive” form of innate immunity . Microbes and Infection vol. 9 , ( 14-15 ) 1680 - 1687 .

Sica A, Rubino L, Mancino A, Larghi P, Porta C, Rimoldi M, Solinas G, Locati M et al. ( 2007 ) . Targeting tumour-associated macrophages . Expert Opinion on Therapeutic Targets vol. 11 , ( 9 ) 1219 - 1229 .

Mantovani A, Garlanda C, Doni A, Bottazzi B ( 2007 ) . Pentraxins in Innate Immunity: From C-Reactive Protein to the Long Pentraxin PTX3 . Journal of Clinical Immunology vol. 28 , ( 1 ) 1 - 13 .

Garlanda C, Di Liberto D, Vecchi A, La Manna MP, Buracchi C, Caccamo N, Salerno A, Dieli F et al. ( 2007 ) . Damping Excessive Inflammation and Tissue Damage in Mycobacterium tuberculosis Infection by Toll IL-1 Receptor 8/Single Ig IL-1-Related Receptor, a Negative Regulator of IL-1/TLR Signaling . The Journal of Immunology vol. 179 , ( 5 ) 3119 - 3125 .

Mantovani A, Marchesi F, Porta C ( 2007 ) . Inflammation and cancer: Breast cancer as a prototype . The Breast vol. 16 , 27 - 33 .

Scarchilli L, Camaioni A, Bottazzi B, Negri V, Doni A, Deban L, Bastone A, Salvatori G et al. ( 2007 ) . PTX3 Interacts with Inter-α-trypsin Inhibitor IMPLICATIONS FOR HYALURONAN ORGANIZATION AND CUMULUS OOPHORUS EXPANSION * ♦ . Journal of Biological Chemistry vol. 282 , ( 41 ) 30161 - 30170 .

de la Torre YM, Garlanda C, Locati M, Vecchi A, Mantovani A ( 2007 ) . Role of the Maternal or Fetal Chemokine Decoy Receptor D6 in Protection against Inflammation‐included Fetal Loss . American Journal Of Reproductive Immunology vol. 58 , ( 3 ) 178 - 178 .

Mantovani A ( 2007 ) . An infernal triangle . Nature vol. 448 , ( 7153 ) 547 - 548 .

Cassatella MA, da Silva GP, Tinazzi I, Facchetti F, Scapini P, Calzetti F, Tamassia N, Wei P et al. ( 2007 ) . Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis . The Journal of Immunology vol. 179 , ( 2 ) 1390 - 1390 .

Garlanda C, Riva F, Veliz T, Polentarutti N, Pasqualini F, Radaelli E, Sironi M, Nebuloni M et al. ( 2007 ) . Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family . Cancer Research vol. 67 , ( 13 ) 6017 - 6021 .

Cassatella MA, da Silva GP, Tinazzi I, Facchetti F, Scapini P, Calzetti F, Tamassia N, Wei P et al. ( 2007 ) . Soluble TNF-Like Cytokine (TL1A) Production by Immune Complexes Stimulated Monocytes in Rheumatoid Arthritis . The Journal of Immunology vol. 178 , ( 11 ) 7325 - 7333 .

Tamassia N, Le Moigne V, Calzetti F, Donini M, Gasperini S, Ear T, Cloutier A, Martinez FO et al. ( 2007 ) . The MYD88-Independent Pathway Is Not Mobilized in Human Neutrophils Stimulated via TLR4 . The Journal of Immunology vol. 178 , ( 11 ) 7344 - 7356 .

Mosca M, Polentarutti N, Mangano G, Apicella C, Doni A, Mancini F, De Bortoli M, Coletta I et al. ( 2007 ) . Regulation of the microsomal prostaglandin E synthase‐1 in polarized mononuclear phagocytes and its constitutive expression in neutrophils . Journal of Leukocyte Biology vol. 82 , ( 2 ) 320 - 326 .

Lech M, Garlanda C, Mantovani A, Kirschning CJ, Schlöndorff D, Anders H-J ( 2007 ) . Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells . Kidney International vol. 72 , ( 2 ) 182 - 192 .

Gazzaniga S, Bravo AI, Guglielmotti A, van Rooijen N, Maschi F, Vecchi A, Mantovani A, Mordoh J et al. ( 2007 ) . Targeting Tumor-Associated Macrophages and Inhibition of MCP-1 Reduce Angiogenesis and Tumor Growth in a Human Melanoma Xenograft . Journal of Investigative Dermatology vol. 127 , ( 8 ) 2031 - 2041 .

Mantovani A, Garlanda C, Locati M, Rodriguez TV ( 2007 ) . Regulatory pathways in inflammation . Autoimmunity Reviews vol. 7 , ( 1 ) 8 - 11 .

Jaillon S, Peri G, Delneste Y, Frémaux I, Doni A, Moalli F, Garlanda C, Romani L et al. ( 2007 ) . The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps . Journal of Experimental Medicine vol. 204 , ( 4 ) 793 - 804 .

Brandi G, Zanier ER, Longhi L, Peri G, De Simon G, Tettamanti M, Mantovani A, Stocchetti N ( 2007 ) . Aneurysmal subarachnoid hemorrhage induces the expression of Pentraxin3 in patients . Critical Care vol. 11 , ( Suppl 2 )

Bonecchi R, Borroni E, Doni A, Anselmo A, Mantovani A, Locati M ( 2007 ) . Rab11-dependent ligand-induced upregulation of the chemokine decoy receptor D6 . GBM Annual Spring meeting Mosbach 2007 vol. 2007 , ( Spring )

de la Torre YM, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A et al. ( 2007 ) . Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6 . Proceedings of the National Academy of Sciences of the United States of America vol. 104 , ( 7 ) 2319 - 2324 .

Assi F, Fruscio R, Bonardi C, Ghidini A, Allavena P, Mantovani A, Locatelli A ( 2007 ) . Pentraxin 3 in plasma and vaginal fluid in women with preterm delivery* . BJOG An International Journal of Obstetrics & Gynaecology vol. 114 , ( 2 ) 143 - 147 .

Mantovani A, Allavena P, Sica A ( 2007 ) . Chapter 16 Tumor-Associated Macrophages in Cancer Growth and Progression . Cancer Immunotherapy , Elsevier

Allavena P, Marchesi F, Mantovani A ( 2007 ) . Chemokine and Receptor Expression in Tumor Progression . Cytokines in the Genesis and Treatment of Cancer , Springer Nature

Paffoni A, Ragni G, Doni A, Somigliana E, Pasqualini F, Restelli L, Pardi G, Mantovani A et al. ( 2006 ) . Follicular Fluid Levels of the Long Pentraxin PTX3 . Reproductive Sciences vol. 13 , ( 3 ) 226 - 231 .

Mantovani A, Sica A ( 2006 ) . New vistas on macrophage differentiation and activation . European Journal of Immunology vol. 37 , ( 1 ) 14 - 16 .

MANTOVANI A, SOZZANI S, INTRONA M ( 2006 ) . Endothelial Activation by Cytokinesa . Annals of the New York Academy of Sciences vol. 832 , ( 1 ) 93 - 116 .

Saccani A, Schioppa T, Porta C, Biswas SK, Nebuloni M, Vago L, Bottazzi B, Colombo MP et al. ( 2006 ) . p50 Nuclear Factor-κB Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance . Cancer Research vol. 66 , ( 23 ) 11432 - 11440 .

Mantovani A, Bonecchi R ( 2006 ) . Tuning inflammation and immunity by chemokine sequestration: decoys and more . Nature Reviews Immunology vol. 6 , ( 12 ) 907 - 918 .

Mensah GA, Ryan US, Hooper WC, Engelgau MM, Callow AD, Kapuku GK, Mantovani A ( 2006 ) . Vascular endothelium summary statement II: Cardiovascular disease prevention and control . Vascular Pharmacology vol. 46 , ( 5 ) 318 - 320 .

Martinez FO, Gordon S, Locati M, Mantovani A ( 2006 ) . Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression . The Journal of Immunology vol. 177 , ( 10 ) 7303 - 7311 .

Inoue K, Sugiyama A, Reid PC, Ito Y, Miyauchi K, Mukai S, Sagara M, Miyamoto K et al. ( 2006 ) . Establishment of a High Sensitivity Plasma Assay for Human Pentraxin3 as a Marker for Unstable Angina Pectoris . Arteriosclerosis Thrombosis and Vascular Biology vol. 27 , ( 1 ) 161 - 167 .

Garlanda C, Maina V, Moalli F, Cotena A, Deban L, Doni A, Montanelli A, Mantovani A et al. ( 2006 ) . The Long Pentraxin PTX3, a Soluble Pattern Recognition Receptor Involved in Innate Immunity,Inflammation and Female Fertility . Current Immunology Reviews vol. 2 , ( 4 ) 319 - 329 .

Borroni EM, Buracchi C, de la Torre YM, Galliera E, Vecchi A, Bonecchi R, Mantovani A, Locati M ( 2006 ) . The chemoattractant decoy receptor D6 as a negative regulator of inflammatory responses . Biochemical Society Transactions vol. 34 , ( 6 ) 1014 - 1017 .

Mantovani A, Balkwill F ( 2006 ) . RalB Signaling: A Bridge between Inflammation and Cancer . Cell vol. 127 , ( 1 ) 42 - 44 .

Sordi V, Bianchi G, Buracchi C, Mercalli A, Marchesi F, D'Amico G, Yang C-H, Luini W et al. ( 2006 ) . Differential Effects of Immunosuppressive Drugs on Chemokine Receptor CCR7 in Human Monocyte-Derived Dendritic Cells: Selective Upregulation by Rapamycin . Transplantation vol. 82 , ( 6 ) 826 - 834 .

Mantovani A, Schioppa T, Porta C ( 2006 ) . Role of tumor-associated macrophages in tumor progression and invasion . Cancer and Metastasis Reviews vol. 25 , ( 3 ) 315 - 322 .

Willeke F, Assad A, Findeisen P, Schromm E, Grobholz R, von Gerstenbergk B, Mantovani A, Peri S et al. ( 2006 ) . Overexpression of a member of the pentraxin family (PTX3) in human soft tissue liposarcoma . European Journal of Cancer vol. 42 , ( 15 ) 2639 - 2646 .

Mantovani A, Porta C, Rubino L, Allavena P, Sica A ( 2006 ) . Tumor-associated macrophages (TAMs) as new target in anticancer therapy . Drug Discovery Today Therapeutic Strategies vol. 3 , ( 3 ) 361 - 366 .

Inforzato A, Peri G, Doni A, Garlanda C, Mantovani A, Bastone A, Carpentieri A, Amoresano A et al. ( 2006 ) . Structure and Function of the Long Pentraxin PTX3 Glycosidic Moiety: Fine-Tuning of the Interaction with C1q and Complement Activation . Biochemistry vol. 45 , ( 38 ) 11540 - 11551 .

Mantovani A, Garlanda C, Bottazzi B, Peri G, Doni A, Latini R ( 2006 ) . The long pentraxin PTX3 in vascular pathology . Vascular Pharmacology vol. 45 , ( 5 ) 326 - 330 .

Bottazzi B, Polentarutti N, Balsari A, Boraschi D, Ghezzi P, Salmona M, Mantovani A ( 2006 ) . Chemotactic activity for mononuclear phagocytes of culture supernatants from murine and human tumor cells: Evidence for a role in the regulation of the macrophage content of neoplastic tissues . International Journal of Cancer vol. 31 , ( 1 ) 55 - 63 .

Massazza G, Tomasoni A, Lucchini V, Allavena P, Erba E, Colombo N, Mantovani A, D'Incalci M et al. ( 2006 ) . Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy . International Journal of Cancer vol. 44 , ( 3 ) 494 - 500 .

Bernasconi S, Peri G, Sironi M, Mantovani A ( 2006 ) . Involvement of leukocyte (β2) integrins (CD18/CD11) in human monocyte tumoricidal activity . International Journal of Cancer vol. 49 , ( 2 ) 267 - 273 .

Walter S, Bottazzi B, Govoni D, Colotta F, Mantovani A ( 2006 ) . Macrophage infiltration and growth of sarcoma clones expressing different amounts of monocyte chemotactic protein/JE . International Journal of Cancer vol. 49 , ( 3 ) 431 - 435 .

Peri G, Polentarutti N, Sessa C, Mangioni C, Mantovani A ( 2006 ) . Tumoricidal activity of macrophages isolated from human ascitic and solid ovarian carcinomas: Augmentation by interferon, lymphokines and endotoxin . International Journal of Cancer vol. 28 , ( 2 ) 143 - 152 .

Bottazzi B, Colotta F, Sica A, Nobili N, Mantovani A ( 2006 ) . A chemoattractant expressed in human sarcoma cells (tumor‐derived chemotactic factor, TDCF) is identical to monocyte chemoattractant protein‐1/monocyte chemotactic and activating factor (MCP‐1/MCAF) . International Journal of Cancer vol. 45 , ( 4 ) 795 - 797 .

Colombo N, Peccatori F, Paganin C, Bini S, Brandely M, Mangioni C, Mantovani A, Allavena P ( 2006 ) . Anti‐tumor and immunomodulatory activity of intraperitoneal IFN‐γ in ovarian carcinoma patients with minimal residual tumor after chemotherapy . International Journal of Cancer vol. 51 , ( 1 ) 42 - 46 .

Mantovani A, Dean JH, Jerrells TR, Herberman RB ( 2006 ) . Augmentation of tumoricidal activity of human monocytes and macrophages by lymphokines . International Journal of Cancer vol. 25 , ( 6 ) 691 - 699 .

Mantovani A, Tagliabue A, Dean JH, Jerrells TR, Herberman RB ( 2006 ) . Cytolytic activity of circulating human monocytes on transformed and untransformed human fibroblasts . International Journal of Cancer vol. 23 , ( 1 ) 28 - 31 .

Mantovani A, Jerrells TR, Dean JH, Herberman RB ( 2006 ) . Cytolytic and cytostatic activity on tumor cells of circulating human monocytes . International Journal of Cancer vol. 23 , ( 1 ) 18 - 27 .

Mantovani A, Giavazzi R, Polentarutti N, Spreafico F, Garattini S ( 2006 ) . Divergent effects of macrophage toxins on growth of primary tumors and lung metastases in mice . International Journal of Cancer vol. 25 , ( 5 ) 617 - 620 .

Acero R, Polentarutti N, Bottazzi B, Alberti S, Ricci MR, Bizzi A, Mantovani A ( 2006 ) . Effect of hydrocortisone on the macrophage content, growth and metastasis of transplanted murine tumors . International Journal of Cancer vol. 33 , ( 1 ) 95 - 105 .

Bernasconi S, Matteucci C, Sironi M, Conni M, Colotta F, Mosca M, Colombo N, Bonazzi C et al. ( 2006 ) . Effects of granulocyte‐monocyte colony‐stimulating factor (GM‐CSF) on expression of adhesion molecules and production of cytokines in blood monocytes and ovarian cancer‐associated macrophages . International Journal of Cancer vol. 60 , ( 3 ) 300 - 307 .

Ortaldo JR, Mantovani A, Hobbs D, Rubinstein M, Pestka S, Herberman RB ( 2006 ) . Effects of several species of human leukocyte interferon on cytotoxic activity of NK cells and monocytes . International Journal of Cancer vol. 31 , ( 3 ) 285 - 289 .

Mantovani A, Peri G, Polentarutti N, Bolis G, Mangioni C, Spreafico F ( 2006 ) . Effects on in vitro tumor growth of macrophages isolated from human ascitic ovarian tumors . International Journal of Cancer vol. 23 , ( 2 ) 157 - 164 .

Mantovani A ( 2006 ) . Effects on in vitro tumor growth of murine macrophages isolated from sarcoma lines differing in immunogenicity and metastasizing capacity . International Journal of Cancer vol. 22 , ( 6 ) 741 - 746 .

Allavena P, Grandi M, D'Incalci M, Geri O, Giuliani FC, Mantovani A ( 2006 ) . Human tumor cell lines with pleiotropic drug resistance are efficiently killed by interleukin‐2 activated killer cells and by activated monocytes . International Journal of Cancer vol. 40 , ( 1 ) 104 - 107 .

Erroi A, Sironi M, Chiaffarino F, Zhen‐Guo C, Mengozzi M, Mantovani A ( 2006 ) . IL‐1 and IL‐6 release by tumor‐associated macrophages from human ovarian carcinoma . International Journal of Cancer vol. 44 , ( 5 ) 795 - 801 .

Mantovani A ( 2006 ) . In vitro effects on tumor cells of macrophages isolated from an early‐passage chemically‐induced murine sarcoma and from its spontaneous metastases . International Journal of Cancer vol. 27 , ( 2 ) 221 - 228 .

Allavena P, Introna M, Rambaldi A, Zanaboni F, Rossini S, Villa A, Bassan R, Barbui T et al. ( 2006 ) . Induction of cytotoxicity by interleukin‐2 in tγ‐lymphoproliferative disorders . International Journal of Cancer vol. 37 , ( 1 ) 27 - 33 .

Mantovani A, Sessa C, Peri G, Allavena P, Introna M, Polentarutti N, Mangioni C ( 2006 ) . Intraperitoneal administration of corynebacterium parvum in patients with ascitic ovarian tumors resistant to chemotherapy: Effects on cytotoxicity of tumor‐associated macrophages and NK cells . International Journal of Cancer vol. 27 , ( 4 ) 437 - 446 .

Mussoni L, Riganti M, Acero R, Erroi A, Conforti G, Mantovani A, Donati MB ( 2006 ) . Macrophages associated with murine tumours express plasminogen activator activity . International Journal of Cancer vol. 41 , ( 2 ) 227 - 230 .

Taraboletti G, Perin L, Bottazzi B, Mantovani A, Giavazzi R, Salmona M ( 2006 ) . Membrane fluidity affects tumor‐cell motility, invasion and lung‐colonizing potential . International Journal of Cancer vol. 44 , ( 4 ) 707 - 713 .

Erroi A, Casali B, Donati MB, Mantovani A, Semeraro N ( 2006 ) . Mouse tumor‐associated macrophages do not generate procoagulant activity in response to different stimuli . International Journal of Cancer vol. 41 , ( 1 ) 65 - 68 .

Mantovani A, Allavena P, Sessa C, Bolis G, Mangioni C ( 2006 ) . Natural killer activity of lymphoid cells isolated from human ascitic ovarian tumors . International Journal of Cancer vol. 25 , ( 5 ) 573 - 582 .

Coen D, Bottazzi B, Bini A, Conforti MG, Mantovani A, Mussoni L, Donati MB ( 2006 ) . Plasminogen activator activity of metastatic variants from a murine fibrosarcoma; effect of thrombin in vitro . International Journal of Cancer vol. 32 , ( 1 ) 67 - 70 .

Guarini A, Acero R, Alessio G, Donati MB, Semeraro N, Mantovani A ( 2006 ) . Procoagulant activity of macrophages associated with different murine neoplasms . International Journal of Cancer vol. 34 , ( 4 ) 581 - 586 .

Bottazzi B, Ghezzi P, Taraboletti G, Salmona M, Colombo N, Bonazzi C, Mangloni C, Mantovani A ( 2006 ) . Tumor‐derived chemotactic factor(S) from human ovarian carcinoma: Evidence for a role in the regulation of macrophage content of neoplastic tissues . International Journal of Cancer vol. 36 , ( 2 ) 167 - 173 .

Colotta F, Polentarutti N, Pirelli A, Dibello M, Allavena P, Mantovani A ( 2006 ) . c‐fos proto‐oncogene expression in human NK/LGL cells: Expression is not constitutive and is associated with functional activation . International Journal of Cancer vol. 42 , ( 5 ) 709 - 711 .

Mantovani A ( 2006 ) . Macrophage diversity and polarization: in vivo veritas . Blood vol. 108 , ( 2 ) 408 - 409 .

Bozza S, Bistoni F, Gaziano R, Pitzurra L, Zelante T, Bonifazi P, Perruccio K, Bellocchio S et al. ( 2006 ) . Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation . Blood vol. 108 , ( 10 ) 3387 - 3396 .

Bassan R, Pronesti M, Buzzetti M, Allavena P, Rambaldi A, Mantovani A, Barbui T ( 2006 ) . Autoimmunity and b‐cell dysfunction in chronic proliferative disorders of large granular lymphocytes/natural killer cells . Cancer vol. 63 , ( 1 ) 90 - 95 .

RAMBALDI A, ROSSI V, ALLAVENA P, INTRONA M, LANDOLFO S, BASSAN R, BARBUI T, MANTOVANI A ( 2006 ) . Lymphokine Production in Ty Lymphoproliferative Disorders . Scandinavian Journal of Immunology vol. 23 , ( 2 ) 183 - 188 .

RAMBALDI A, ALESSIO G, ROSSI V, DONATI MB, SEMERARO N, MANTOVANI A ( 2006 ) . Production of Interleukin 1 but not of Procoagulant Activity by Large Granular Lymphocytes . Scandinavian Journal of Immunology vol. 22 , ( 4 ) 363 - 366 .

Rambaldi A, Introna M, Colotta F, Landolfo S, Colombo N, Mangioni C, Mantovani A ( 2006 ) . Intraperitoneal administration of interferon β in ovarian cancer patients . Cancer vol. 56 , ( 2 ) 294 - 301 .

Camozzi M, Rusnati M, Bugatti A, Bottazzi B, Mantovani A, Bastone A, Inforzato A, Vincenti S et al. ( 2006 ) . Identification of an Antiangiogenic FGF2-binding Site in the N Terminus of the Soluble Pattern Recognition Receptor PTX3* . Journal of Biological Chemistry vol. 281 , ( 32 ) 22605 - 22613 .

Sironi M, Martinez FO, D’Ambrosio D, Gattorno M, Polentarutti N, Locati M, Gregorio A, Iellem A et al. ( 2006 ) . Differential regulation of chemokine production by Fcγ receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2) . Journal of Leukocyte Biology vol. 80 , ( 2 ) 342 - 349 .

Mantovani A, Garlanda C ( 2006 ) . Inflammation and multiple myeloma: the Toll connection . Leukemia vol. 20 , ( 6 ) 937 - 938 .

Cetin I, Cozzi V, Pasqualini F, Nebuloni M, Garlanda C, Vago L, Pardi G, Mantovani A ( 2006 ) . Elevated maternal levels of the long pentraxin 3 (PTX3) in preeclampsia and intrauterine growth restriction . American Journal of Obstetrics and Gynecology vol. 194 , ( 5 ) 1347 - 1353 .

Baruah P, Dumitriu IE, Peri G, Russo V, Mantovani A, Manfredi AA, Rovere-Querini P ( 2006 ) . The tissue pentraxin PTX3 limits C1q-mediated complement activation and phagocytosis of apoptotic cells by dendritic cells . Journal of Leukocyte Biology vol. 80 , ( 1 ) 87 - 95 .

Soares AC, Souza DG, Pinho V, Vieira AT, Nicoli JR, Cunha FQ, Mantovani A, Reis LFL et al. ( 2006 ) . Dual function of the long pentraxin PTX3 in resistance against pulmonary infection with Klebsiella pneumoniae in transgenic mice . Microbes and Infection vol. 8 , ( 5 ) 1321 - 1329 .

Sironi M, Conti A, Bernasconi S, Fra AM, Pasqualini F, Nebuloni M, Lauri E, De Bortoli M et al. ( 2006 ) . Generation and characterization of a mouse lymphatic endothelial cell line . Cell and Tissue Research vol. 325 , ( 1 ) 91 - 100 .

Roumenina LT, Ruseva MM, Zlatarova A, Ghai R, Kolev M, Olova N, Gadjeva M, Agrawal A et al. ( 2006 ) . Interaction of C1q with IgG1, C-reactive Protein and Pentraxin 3: Mutational Studies Using Recombinant Globular Head Modules of Human C1q A, B, and C Chains † . Biochemistry vol. 45 , ( 13 ) 4093 - 4104 .

Sica A, Schioppa T, Mantovani A, Allavena P ( 2006 ) . Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy . European Journal of Cancer vol. 42 , ( 6 ) 717 - 727 .

Bottazzi B, Bastone A, Doni A, Garlanda C, Valentino S, Deban L, Maina V, Cotena A et al. ( 2006 ) . The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertility . Journal of Leukocyte Biology vol. 79 , ( 5 ) 909 - 912 .

MANTOVANI A, MUZIO M, GHEZZI P, COLOTTA C, INTRONA M ( 2006 ) . Regulation of Inhibitory Pathways of the Interleukin‐1 System . Annals of the New York Academy of Sciences vol. 840 , ( 1 ) 338 - 351 .

Doni A, Michela M, Bottazzi B, Peri G, Valentino S, Polentarutti N, Garlanda C, Mantovani A ( 2006 ) . Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-γ . Journal of Leukocyte Biology vol. 79 , ( 4 ) 797 - 802 .

Mantovani A, Maranghi F, Purificato I, Macrì A ( 2006 ) . Assessment of feed additives and contaminants: an essential component of food safety . Annali dell Istituto Superiore di Sanità vol. 42 , ( 4 ) 427 - 432 .

Locati M, de la Torre YM, Galliera E, Bonecchi R, Vago G, Vecchi A, Mantovani A ( 2006 ) . D6 as a Decoy and Scavenger Receptor for Inflammatory CC Chemokines in the Skin . Elsevier

Marchesi P, Norata GD, Mantovani A, Fazia M, Cipollone F, Mezzetti A, Chiesa G, Catapano AL ( 2006 ) . Th-P15:199 Modulation of pentraxin 3 expression in endothelial cells: Role of HDL . Atherosclerosis Plus . vol. 7 ,

Baruah P, Propato A, Dumitriu IE, Rovere-Querini P, Russo V, Fontana R, Accapezzato D, Peri G et al. ( 2005 ) . The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells, and edits the cross-presentation of self, viral, and tumor antigens . Blood vol. 107 , ( 1 ) 151 - 158 .

Bottazzi B, Garlanda C, Salvatori G, Jeannin P, Manfredi A, Mantovani A ( 2005 ) . Pentraxins as a key component of innate immunity . Current Opinion in Immunology vol. 18 , ( 1 ) 10 - 15 .

del Papa N, Guidali L, Sironi M, Shoenfeld Y, Mantovani A, Tincani A, Balestrieri G, Radice A et al. ( 2005 ) . Anti‐endothelial cell IgG antibodies from patients with Wegener's granulomatosis bind to human endothelial cells in vitro and induce adhesion molecule expression and cytokine secretion . Arthritis & Rheumatism vol. 39 , ( 5 ) 758 - 766 .

Sironi M, Muñoz C, Pollicino T, Siboni A, Sciacca FL, Bernasconi S, Yecchi A, Colotta F et al. ( 2005 ) . Divergent effects of interleukin‐10 on cytokine production by mononuclear phagocytes and endothelial cells . European Journal of Immunology vol. 23 , ( 10 ) 2692 - 2695 .

Re F, Mengozzi M, Muzio M, Dinarello CA, Mantovani A, Colotta F ( 2005 ) . Expression of interleukin‐1 receptor antagonist (IL‐1ra) by human circulating polymorphonuclear cells . European Journal of Immunology vol. 23 , ( 2 ) 570 - 573 .

Jonjic N, Alberti S, Bernasconi S, Peri G, Jilek P, Anichini A, Parmiani G, Mantovani A ( 2005 ) . Heterogeneous susceptibility of human melanoma clones to monocyte cytotoxicity: Role of ICAM‐1 defined by antibody blocking and gene transfer . European Journal of Immunology vol. 22 , ( 9 ) 2255 - 2260 .

Van Damme J, Decock B, Lenaerts J, Conings R, Bertini R, Mantovani A, Billiau A ( 2005 ) . Identification by sequence analysis of chemotactic factors for monocytes produced by normal and transformed cells stimulated with virus, double‐stranded RNA or cytokine . European Journal of Immunology vol. 19 , ( 12 ) 2367 - 2373 .

Muzio M, Sironi M, Polentarutti N, Mantovani A, Colotta F ( 2005 ) . Induction by transforming growth factor‐β1 of the interleukin‐1 receptor antagonist and of its intracellular form in human polymorphonuclear cells . European Journal of Immunology vol. 24 , ( 12 ) 3194 - 3198 .

Allavena P, Bianchi G, Zhou D, Van Damme J, Jílek P, Sozzani S, Mantovani A ( 2005 ) . Induction of natural killer cell migration by monocyte chemotactic protein−1, −2 and −3 . European Journal of Immunology vol. 24 , ( 12 ) 3233 - 3236 .

Righi M, Mori L, De Libero G, Sironi M, Biondi A, Mantovani A, Donini SD, Ricciardi‐Castagnoli P ( 2005 ) . Monokine production by microglial cell clones . European Journal of Immunology vol. 19 , ( 8 ) 1443 - 1448 .

Biondi A, Rossi V, Benvestito S, Paganin C, Allavena P, Mantovani A, Perlmutter RM ( 2005 ) . Expression of lineage‐restricted protein tyrosine kinase genes in human natural killer cells . European Journal of Immunology vol. 21 , ( 3 ) 843 - 846 .

Wang JM, Rambaldi A, Biondi A, Chen ZG, Sanderson CJ, Mantovani A ( 2005 ) . Recombinant human interleukin 5 is a selective eosinophil chemoattractant . European Journal of Immunology vol. 19 , ( 4 ) 701 - 705 .

Tagliabue A, Mantovani A, Boraschi D, Herberman RB ( 2005 ) . Species‐restricted effects of human and mouse lymphokines on macrophages . European Journal of Immunology vol. 10 , ( 7 ) 542 - 546 .

Sozzani S, Bosisio D, Mantovani A, Ghezzi P ( 2005 ) . Linking stress, oxidation and the chemokine system . European Journal of Immunology vol. 35 , ( 11 ) 3095 - 3098 .

Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A et al. ( 2005 ) . A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation) . Blood vol. 107 , ( 5 ) 2112 - 2122 .

Cassatella MA, Huber V, Calzetti F, Margotto D, Tamassia N, Peri G, Mantovani A, Rivoltini L et al. ( 2005 ) . Interferon-activated neutrophils store a TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) intracellular pool that is readily mobilizable following exposure to proinflammatory mediators . Journal of Leukocyte Biology vol. 79 , ( 1 ) 123 - 132 .

Colombo MP, Mantovani A ( 2005 ) . Targeting Myelomonocytic Cells to Revert Inflammation-Dependent Cancer Promotion . Cancer Research vol. 65 , ( 20 ) 9113 - 9116 .

Roumenina LT, Kantardjiev AA, Atanasov BP, Waters P, Gadjeva M, Reid KBM, Mantovani A, Kishore U et al. ( 2005 ) . Role of Ca2+ in the Electrostatic Stability and the Functional Activity of the Globular Domain of Human C1q † . Biochemistry vol. 44 , ( 43 ) 14097 - 14109 .

Borrello MG, Alberti L, Fischer A, Degl'Innocenti D, Ferrario C, Gariboldi M, Marchesi F, Allavena P et al. ( 2005 ) . Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene . Proceedings of the National Academy of Sciences of the United States of America vol. 102 , ( 41 ) 14825 - 14830 .

Mantovani A, Sica A, Locati M ( 2005 ) . Macrophage Polarization Comes of Age . Immunity vol. 23 , ( 4 ) 344 - 346 .

Van Damme J, Mantovani A ( 2005 ) . From cytokines to chemokines . Cytokine & Growth Factor Reviews vol. 16 , ( 6 ) 549 - 551 .

Camozzi M, Zacchigna S, Rusnati M, Coltrini D, Ramirez-Correa G, Bottazzi B, Mantovani A, Giacca M et al. ( 2005 ) . Pentraxin 3 Inhibits Fibroblast Growth Factor 2–Dependent Activation of Smooth Muscle Cells In Vitro and Neointima Formation In Vivo . Arteriosclerosis Thrombosis and Vascular Biology vol. 25 , ( 9 ) 1837 - 1842 .

Locati M, de la Torre YM, Galliera E, Bonecchi R, Bodduluri H, Vago G, Vecchi A, Mantovani A ( 2005 ) . Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines . Cytokine & Growth Factor Reviews vol. 16 , ( 6 ) 679 - 686 .

Mairuhu ATA, Peri G, Setiati TE, Hack CE, Koraka P, Soemantri A, Osterhaus ADME, Brandjes DPM et al. ( 2005 ) . Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections . Journal of Medical Virology vol. 76 , ( 4 ) 547 - 552 .

Mantovani A ( 2005 ) . Inflammation by remote control . Nature vol. 435 , ( 7043 ) 752 - 753 .

Raes G, Van den Bergh R, De Baetselier P, Ghassabeh GH, Scotton C, Locati M, Mantovani A, Sozzani S ( 2005 ) . Arginase-1 and Ym1 Are Markers for Murine, but Not Human, Alternatively Activated Myeloid Cells . The Journal of Immunology vol. 174 , ( 11 ) 6561 - 6562 .

Jeannin P, Bottazzi B, Sironi M, Doni A, Rusnati M, Presta M, Maina V, Magistrelli G et al. ( 2005 ) . Complexity and Complementarity of Outer Membrane Protein A Recognition by Cellular and Humoral Innate Immunity Receptors . Immunity vol. 22 , ( 5 ) 551 - 560 .

de la Torre YM, Locati M, Buracchi C, Dupor J, Cook DN, Bonecchi R, Nebuloni M, Rukavina D et al. ( 2005 ) . Increased inflammation in mice deficient for the chemokine decoy receptor D6 . European Journal of Immunology vol. 35 , ( 5 ) 1342 - 1346 .

Garlanda C, Bottazzi B, Bastone A, Mantovani A ( 2005 ) . PENTRAXINS AT THE CROSSROADS BETWEEN INNATE IMMUNITY, INFLAMMATION, MATRIX DEPOSITION, AND FEMALE FERTILITY . Annual Review of Immunology vol. 23 , ( 1 ) 337 - 366 .

Laskarin G, Cupurdija K, Tokmadzic VS, Dorcic D, Dupor J, Juretic K, Strbo N, Crncic TB et al. ( 2005 ) . The presence of functional mannose receptor on macrophages at the maternal–fetal interface . Human Reproduction vol. 20 , ( 4 ) 1057 - 1066 .

Mauri T, Bombino M, Bertoli E, Doni A, Mantovani A, Pesenti A ( 2005 ) . Circulating levels of the long pentraxin PTX3, an acute phase mediator of innate immunity, in acute lung injury/acute respiratory distress syndrome: functional and prognostic correlations . Critical Care vol. 9 , ( Suppl 1 )

Van DAMME J, DECOCK B, BERTINI R, CONINGS R, LENAERTS J, Willy P, OPDENAKKER G, MANTOVANI A ( 2005 ) . Production and identification of natural monocyte chemotactic protein from virally infected murine fibroblasts . The FEBS Journal vol. 199 , ( 1 ) 223 - 229 .

Balkwill F, Charles KA ( 2005 ) . Smoldering and polarized inflammation in the initiation and promotion of malignant disease . Cancer Cell vol. 7 , ( 3 ) 211 - 217 .

Vermi W, Riboldi E, Wittamer V, Gentili F, Luini W, Marrelli S, Vecchi A, Franssen J-D et al. ( 2005 ) . Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin . Journal of Experimental Medicine vol. 201 , ( 4 ) 509 - 515 .

Bocchietto E, Guglielmetti A, Silvagno F, Taraboletti G, Pescarmona GP, Mantovani A, Bussolino F ( 2005 ) . Proliferative and migratory responses of murine microvascular endothelial cells to granulocyte‐colony‐stimulating factor . Journal of Cellular Physiology vol. 155 , ( 1 ) 89 - 95 .

Mattoli S, Colotta F, Fincato G, Mezzetti M, Mantovani A, Patalano F, Fasoli A ( 2005 ) . Time course of IL1 and IL6 synthesis and release in human bronchial epithelial cell cultures exposed to toluene diisocyanate . Journal of Cellular Physiology vol. 149 , ( 2 ) 260 - 268 .

Mantovani A, Garlanda C, Otero K, Peri G, Vecchi A, Bottazzi B ( 2004 ) . Membrane and soluble pattern recognition receptors: the unique functions of the long pentraxin PTX3 . Clinical & Experimental Allergy Reviews . vol. 4 , 150 - 154 .

Nauta AJ, De Haij S, Bottazzi B, Mantovani A, Borrias MC, Aten JAN, Rastaldi MPIA, Daha MR et al. ( 2005 ) . Human renal epithelial cells produce the long pentraxin PTX3 . Kidney International vol. 67 , ( 2 ) 543 - 553 .

Scotton CJ, Martinez FO, Smelt MJ, Sironi M, Locati M, Mantovani A, Sozzani S ( 2005 ) . Transcriptional Profiling Reveals Complex Regulation of the Monocyte IL-1β System by IL-13 . The Journal of Immunology vol. 174 , ( 2 ) 834 - 845 .

Allavena P, Marchesi F, Mantovani A ( 2005 ) . The Role of Chemokines and their Receptors in Tumor Progression and Invasion: Potential New Targets of Biological Therapy . Current Cancer Therapy Reviews vol. 1 , ( 1 ) 81 - 92 .

Garlanda C, Mosca M, Cotena A, Maina V, Moalli F, Riva F, Mantovani A ( 2005 ) . Tuning of inflammatory cytokines and toll-like receptors by TIR8/SIGIRR, a member of the IL-1 receptor family with unique structure and regulation . Toll-like Receptors in Inflammation , Springer Nature

Allavena P, Luini W, Bonecchi R, D'Amico G, Bianchi G, Longoni D, Vecchi A, Mantovani A et al. ( 2004 ) . Chemokines and Chemokine Receptors in the Regulation of Dendritic Cell Trafficking . Chemical Immunology and Allergy vol. 72 , 69 - 85 .

Mantovani A ( 2004 ) . Introduction and Overview . Chemokines , vol. 72 , Karger Publishers

Locatelli A, Bonardi C, Assi F, Ghidini A, Garlanda C, Mantovani A ( 2004 ) . Effects of corticosteroid therapy on vaginal and serum pentraxin (PTX)-3 concentrations . American Journal of Obstetrics and Gynecology . vol. 191 ,

Bonardi C, Assi F, Locatelli A, Ghidini A, Garlanda C, Mantovani A ( 2004 ) . Pentraxin (PTX)-3 in preterm labor and premature rupture of membranes (PROM): A marker of intrauterine infection? . American Journal of Obstetrics and Gynecology . vol. 191 ,

Assi F, Locatelli A, Bonardi C, Ghidini A, Fruscio R, Garlanda C, Mantovani A ( 2004 ) . Role of the long pentraxin (PTX)-3 in preterm labor (PTL) and premature rupture of membranes (PROM) . American Journal of Obstetrics and Gynecology . vol. 191 ,

Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M ( 2004 ) . The chemokine system in diverse forms of macrophage activation and polarization . Trends in Immunology vol. 25 , ( 12 ) 677 - 686 .

Azzurri A, Sow OY, Amedei A, Bah B, Diallo S, Peri G, Benagiano M, D’Elios MM et al. ( 2004 ) . IFN-γ-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection . Microbes and Infection vol. 7 , ( 1 ) 1 - 8 .

Marchesi F, Monti P, Leone BE, Zerbi A, Vecchi A, Piemonti L, Mantovani A, Allavena P ( 2004 ) . Increased Survival, Proliferation, and Migration in Metastatic Human Pancreatic Tumor Cells Expressing Functional CXCR4 . Cancer Research vol. 64 , ( 22 ) 8420 - 8427 .

Gaziano R, Bozza S, Bellocchio S, Perruccio K, Montagnoli C, Pitzurra L, Salvatori G, De Santis R et al. ( 2004 ) . Anti-Aspergillus fumigatus Efficacy of Pentraxin 3 Alone and in Combination with Antifungals . Antimicrobial Agents and Chemotherapy vol. 48 , ( 11 ) 4414 - 4421 .

Latini R, Maggioni AP, Peri G, Gonzini L, Lucci D, Mocarelli P, Vago L, Pasqualini F et al. ( 2004 ) . Prognostic Significance of the Long Pentraxin PTX3 in Acute Myocardial Infarction . Circulation vol. 110 , ( 16 ) 2349 - 2354 .

Rosaria M, Del Prete A, Vecchi A, Corada M, Martin-Padura I, Motoike T, Tonetti P, Bazzoni G et al. ( 2004 ) . Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A–deficient mice . Journal of Clinical Investigation vol. 114 , ( 5 ) 729 - 738 .

al-Ramadi BK, Ellis M, Pasqualini F, Mantovani A ( 2004 ) . Selective induction of pentraxin 3, a soluble innate immune pattern recognition receptor, in infectious episodes in patients with haematological malignancy . Clinical Immunology vol. 112 , ( 3 ) 221 - 224 .

Valerio A, Ferrario M, Martinez FO, Locati M, Ghisi V, Bresciani LG, Mantovani A, Spano P ( 2004 ) . Expression of Concern: Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells . Journal of Neuroscience Research vol. 78 , ( 3 ) 371 - 382 .

Simon A, Bijzet J, Voorbij HAM, Mantovani A, Van Der Meer JWM, Drenth JPH ( 2004 ) . Effect of inflammatory attacks in the classical type hyper‐IgD syndrome on immunoglobulin D, cholesterol and parameters of the acute phase response . Journal of Internal Medicine vol. 256 , ( 3 ) 247 - 253 .

Del Prete A, Vermi W, Dander E, Otero K, Barberis L, Luini W, Bernasconi S, Sironi M et al. ( 2004 ) . Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ‐deficient mice . The EMBO Journal vol. 23 , ( 17 ) 3505 - 3515 .

van Rossum AP, Fazzini F, Limburg PC, Manfredi AA, Rovere‐Querini P, Mantovani A, Kallenberg CGM ( 2004 ) . The prototypic tissue pentraxin PTX3, in contrast to the short pentraxin serum amyloid P, inhibits phagocytosis of late apoptotic neutrophils by macrophages . Arthritis & Rheumatism vol. 50 , ( 8 ) 2667 - 2674 .

Perrier P, Martinez FO, Locati M, Bianchi G, Nebuloni M, Vago G, Bazzoni F, Sozzani S et al. ( 2004 ) . Distinct Transcriptional Programs Activated by Interleukin-10 with or without Lipopolysaccharide in Dendritic Cells: Induction of the B Cell-Activating Chemokine, CXC Chemokine Ligand 13 . The Journal of Immunology vol. 173 , ( 3 ) 2199 - 2200 .

Klouche M, Peri G, Knabbe C, Eckstein H-H, Schmid F-X, Schmitz G, Mantovani A ( 2004 ) . Modified atherogenic lipoproteins induce expression of pentraxin-3 by human vascular smooth muscle cells . Atherosclerosis vol. 175 , ( 2 ) 221 - 228 .

Bertini R, Allegretti M, Bizzarri C, Moriconi A, Locati M, Zampella G, Cervellera MN, Di Cioccio V et al. ( 2004 ) . Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: Prevention of reperfusion injury . Proceedings of the National Academy of Sciences of the United States of America vol. 101 , ( 32 ) 11791 - 11796 .

Napoleone E, Di Santo A, Peri G, Mantovani A, de Gaetano G, Donati MB, Lorenzet R ( 2004 ) . The long pentraxin PTX3 up-regulates tissue factor in activated monocytes: another link between inflammation and clotting activation . Journal of Leukocyte Biology vol. 76 , ( 1 ) 203 - 209 .

Mantovani A, Allavena P, Sica A ( 2004 ) . Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression . European Journal of Cancer vol. 40 , ( 11 ) 1660 - 1667 .

Martinez FO, Sironi M, Vecchi A, Colotta F, Mantovani A, Locati M ( 2004 ) . IL‐8 induces a specific transcriptional profile in human neutrophils: synergism with LPS for IL‐1 production . European Journal of Immunology vol. 34 , ( 8 ) 2286 - 2292 .

Mantovani A, Allavena P, Sozzani S, Vecchi A, Locati M, Sica A ( 2004 ) . Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors . Seminars in Cancer Biology vol. 14 , ( 3 ) 155 - 160 .

Perrier P, Martinez FO, Locati M, Bianchi G, Nebuloni M, Vago G, Bazzoni F, Sozzani S et al. ( 2004 ) . Distinct Transcriptional Programs Activated by Interleukin-10 with or without Lipopolysaccharide in Dendritic Cells: Induction of the B Cell-Activating Chemokine, CXC Chemokine Ligand 13 . The Journal of Immunology vol. 172 , ( 11 ) 7031 - 7042 .

Mantovani A ( 2004 ) . Editorial . Seminars in Cancer Biology vol. 14 , ( 3 ) 147 - 148 .

Bottazzi B, Peri G, Garlanda C, Doni A, Baviera S, Latini R, Maggioni A, Mantovani A ( 2004 ) . The long pentraxin PTX3: from innate immunity to ischemic heart disorders . International Congress Series vol. 1262 , 63 - 66 .

Bonecchi R, Locati M, Galliera E, Vulcano M, Sironi M, Fra AM, Gobbi M, Vecchi A et al. ( 2004 ) . Differential Recognition and Scavenging of Native and Truncated Macrophage-Derived Chemokine (Macrophage-Derived Chemokine/CC Chemokine Ligand 22) by the D6 Decoy Receptor . The Journal of Immunology vol. 172 , ( 8 ) 4972 - 4976 .

Galliera E, Jala VR, Trent JO, Bonecchi R, Signorelli P, Lefkowitz RJ, Mantovani A, Locati M et al. ( 2004 ) . β-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6* . Journal of Biological Chemistry vol. 279 , ( 24 ) 25590 - 25597 .

Rusnati M, Camozzi M, Moroni E, Bottazzi B, Peri G, Indraccolo S, Amadori A, Mantovani A et al. ( 2004 ) . Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis . Blood vol. 104 , ( 1 ) 92 - 99 .

Salustri A, Garlanda C, Hirsch E, De Acetis M, Maccagno A, Bottazzi B, Doni A, Bastone A et al. ( 2004 ) . PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization . Development vol. 131 , ( 7 ) 1577 - 1586 .

Garlanda C, Riva F, Polentarutti N, Buracchi C, Sironi M, De Bortoli M, Muzio M, Bergottini R et al. ( 2004 ) . Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family . Proceedings of the National Academy of Sciences of the United States of America vol. 101 , ( 10 ) 3522 - 3526 .

Gazzaniga S, González L, Mantovani A, Vecchi A, Wainstok R ( 2004 ) . Isolation and molecular characterization of a mouse renal microvascular endothelial cell line . In Vitro Cellular & Developmental Biology - Animal vol. 40 , ( 3-4 ) 82 - 88 .

Bellocchio S, Montagnoli C, Bozza S, Gaziano R, Rossi G, Mambula SS, Vecchi A, Mantovani A et al. ( 2004 ) . The Contribution of the Toll-Like/IL-1 Receptor Superfamily to Innate and Adaptive Immunity to Fungal Pathogens In Vivo . The Journal of Immunology vol. 172 , ( 5 ) 3059 - 3069 .

Diniz SN, Nomizo R, Cisalpino PS, Teixeira MM, Brown GD, Mantovani A, Gordon S, Reis LFL et al. ( 2004 ) . PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophages . Journal of Leukocyte Biology vol. 75 , ( 4 ) 649 - 656 .

Sozzani S, Vecchi A, Allavena P, Mantovani A ( 2004 ) . Chemotaxis and Interaction with Vascular or Lymphatic Endothelium . Cell Migration in Inflammation and Immunity , vol. 239 , Springer Nature

Sozzani S, Vecchi A, Allavena P, Mantovani A ( 2004 ) . Chemotaxis and interaction with vascular or lymphatic endothelium . vol. 239 , 1 - 16 .

Boraschi D, Mantovani G, Tagliabue A, Mantovani A ( 2004 ) . Cytokine Receptors . Encyclopedia of Endocrine Diseases , Elsevier

Gazzaniga S, Gonzãlez L, Mantovani A, Vecchi A, Wainstok R ( 2004 ) . ISOLATION AND MOLECULAR CHARACTERIZATION OF A MOUSE RENAL MICROVASCULAR ENDOTHELIAL CELL LINE . In Vitro Cellular & Developmental Biology - Animal

Luchetti MM, Sambo P, Majlingová P, Svegliati Baroni S, Peri G, Paroncini P, Introna M, Stoppacciaro A et al. ( 2004 ) . Scleroderma fibroblasts constitutively express the long pentraxin PTX3 . Clinical and Experimental Rheumatology vol. 22 , ( 3 Suppl 33 ) s66 - s72 .

Mantovani A, Locati M, Polentarutti N, Vecchi A, Garlanda C ( 2003 ) . Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR . Journal of Leukocyte Biology vol. 75 , ( 5 ) 738 - 742 .

Mancini F, Landolfi C, Muzio M, Aquilini L, Soldo L, Coletta I, Guglielmotti A, Mantovani A et al. ( 2003 ) . Acetaminophen down-regulates interleukin-1β-induced nuclear factor-κB nuclear translocation in a human astrocytic cell line . Neuroscience Letters vol. 353 , ( 2 ) 79 - 82 .

Vicenzi E, Bagnarelli P, Santagostino E, Ghezzi S, Alfano M, Sinnone MS, Fabio G, Turchetto L et al. ( 2003 ) . Hemophilia and nonprogressing human immunodeficiency virus type 1 infection . Haemophilia vol. 3 , ( 3 ) 232 - 232 .

Schioppa T, Uranchimeg B, Saccani A, Biswas SK, Doni A, Rapisarda A, Bernasconi S, Saccani S et al. ( 2003 ) . Regulation of the Chemokine Receptor CXCR4 by Hypoxia . Journal of Experimental Medicine vol. 198 , ( 9 ) 1391 - 1402 .

Mantovani A, Bonecchi R, Martinez FO, Galliera E, Perrier P, Allavena P, Locati M ( 2003 ) . Tuning of Innate Immunity and Polarized Responses by Decoy Receptors . International Archives of Allergy and Immunology vol. 132 , ( 2 ) 109 - 115 .

Chieppa M, Bianchi G, Doni A, Del Prete A, Sironi M, Laskarin G, Monti P, Piemonti L et al. ( 2003 ) . Cross-Linking of the Mannose Receptor on Monocyte-Derived Dendritic Cells Activates an Anti-Inflammatory Immunosuppressive Program . The Journal of Immunology vol. 171 , ( 9 ) 4552 - 4560 .

Wittamer V, Franssen J-D, Vulcano M, Mirjolet J-F, Le Poul E, Migeotte I, Brézillon S, Tyldesley R et al. ( 2003 ) . Specific Recruitment of Antigen-presenting Cells by Chemerin, a Novel Processed Ligand from Human Inflammatory Fluids . Journal of Experimental Medicine vol. 198 , ( 7 ) 977 - 985 .

Doni A, Peri G, Chieppa M, Allavena P, Pasqualini F, Vago L, Romani L, Garlanda C et al. ( 2003 ) . Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells . European Journal of Immunology vol. 33 , ( 10 ) 2886 - 2893 .

Mantovani A, Schioppa T, Biswas SK, Marchesi F, Allavena P, Sica A ( 2003 ) . Tumor-Associated Macrophages and Dendritic Cells as Prototypic Type II Polarized Myeloid Populations . Tumori Journal vol. 89 , ( 5 ) 459 - 468 .

Bourke E, Cassetti A, Villa A, Fadlon E, Colotta F, Mantovani A ( 2003 ) . IL-1β Scavenging by the Type II IL-1 Decoy Receptor in Human Neutrophils . The Journal of Immunology vol. 170 , ( 12 ) 5999 - 6005 .

Mantovani A, Garlanda C, Bottazzi B ( 2003 ) . Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity . Vaccine vol. 21 , s43 - s47 .

Mantovani A, Sica A ( 2003 ) . Response to Hellstrand: The jury on radicals is still out . Trends in Immunology vol. 24 , ( 5 )

Bourke E, Bosisio D, Golay J, Polentarutti N, Mantovani A ( 2003 ) . The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells . Blood vol. 102 , ( 3 ) 956 - 963 .

Vulcano M, Struyf S, Scapini P, Cassatella M, Bernasconi S, Bonecchi R, Calleri A, Penna G et al. ( 2003 ) . Unique Regulation of CCL18 Production by Maturing Dendritic Cells . The Journal of Immunology vol. 170 , ( 7 ) 3843 - 3849 .

Latini R, Fratto P, Frigerio M, Oliva F, Peri G, Mantovani A, Pasqualini F, Signorini S et al. ( 2003 ) . A novel long-pentraxin PTX3, C-reactive protein, NT-Pro-BNP and troponin-T during the first six months after heart transplant . Journal of the American College of Cardiology . vol. 41 ,

Tacchini L, Fusar-Poli D, Sironi M, Mantovani A, Bernelli-Zazzera A ( 2003 ) . Activation of signal transducer and activator of transcription 3 in rat liver after heat shock and reperfusion stress . The International Journal of Biochemistry & Cell Biology vol. 35 , ( 3 ) 316 - 323 .

Abderrahim-Ferkoune A, Bezy O, Chiellini C, Maffei M, Grimaldi P, Bonino F, Moustaid-Moussa N, Pasqualini F et al. ( 2003 ) . Characterization of the long pentraxin PTX3 as a TNFα-induced secreted protein of adipose cells . Journal of Lipid Research vol. 44 , ( 5 ) 994 - 1000 .

Fra AM, Locati M, Otero K, Sironi M, Signorelli P, Massardi ML, Gobbi M, Vecchi A et al. ( 2003 ) . Cutting Edge: Scavenging of Inflammatory CC Chemokines by the Promiscuous Putatively Silent Chemokine Receptor D6 . The Journal of Immunology vol. 170 , ( 5 ) 2279 - 2282 .

Allavena P, Sica A, Vecchi A, Locati M, Sozzani S, Mantovani A ( 2003 ) . The chemokine receptor switch paradigm and dendritic cell migration: its significance in tumor tissues . Immunological Reviews vol. 177 , ( 1 ) 141 - 149 .

Bussolati B, Peri G, Salvidio G, Verzola D, Mantovani A, Camussi G ( 2003 ) . The Long Pentraxin Ptx3 Is Synthesized in IgA Glomerulonephritis and Activates Mesangial Cells . The Journal of Immunology vol. 170 , ( 3 ) 1466 - 1472 .

Nauta AJ, Bottazzi B, Mantovani A, Salvatori G, Kishore U, Schwaeble WJ, Gingras AR, Tzima S et al. ( 2003 ) . Biochemical and functional characterization of the interaction between pentraxin 3 and C1q . European Journal of Immunology vol. 33 , ( 2 ) 465 - 473 .

Raschi E, Testoni C, Bosisio D, Borghi MO, Koike T, Mantovani A, Meroni PL ( 2003 ) . Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies . Blood vol. 101 , ( 9 ) 3495 - 3500 .

Bottazzi B, Peri G, Garlanda C, Latini R, Maggioni A, Mantovani A ( 2003 ) . 1SY02-4 The long pentraxin PTX3: From innate immunity to ischemic heart disorders . Atherosclerosis Plus . vol. 4 ,

Mantovani A, Locati M, Sozzani S ( 2003 ) . Chapter 47 CC chemokines . The Cytokine Handbook , vol. II , Elsevier

Kaplanski G, Marin V, Montero-Julian F, Mantovani A, Farnarier C ( 2003 ) . IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation . Trends in Immunology vol. 24 , ( 1 ) 25 - 29 .

Mantovani A ( 2003 ) . Interleukin-1 (IL-1) . Encyclopedia of Hormones , Elsevier

Polentarutti N, Rol GP, Muzio M, Bosisio D, Camnasio M, Riva F, Zoja C, Benigni A et al. ( 2003 ) . Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR . European Cytokine Network vol. 14 , ( 4 ) 211 - 218 .

Deslée GT, Charbonnier A-S, Hammad H, Angyalosi G, Tillie-Leblond I, Mantovani A, Tonnel AÉ-B, Pestel J ( 2002 ) . Involvement of the mannose receptor in the uptake of der p 1, a major mite allergen, by human dendritic cells . The Journal of Allergy and Clinical Immunology vol. 110 , ( 5 ) 763 - 770 .

Mantovani A, Sozzani S, Locati M, Allavena P, Sica A ( 2002 ) . Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes . Trends in Immunology vol. 23 , ( 11 ) 549 - 555 .

Garlanda C, Hirsch E, Bozza S, Salustri A, De Acetis M, Nota R, Maccagno A, Riva F et al. ( 2002 ) . Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response . Nature vol. 420 , ( 6912 ) 182 - 186 .

Locati M, Otero K, Schioppa T, Signorelli P, Perrier P, Baviera S, Sozzani S, Mantovani A ( 2002 ) . The chemokine system: tuning and shaping by regulation of receptor expression and coupling in polarized responses . Allergy vol. 57 , ( 11 ) 972 - 982 .

Bacon K, Baggiolini M, Broxmeyer H, Horuk R, Lindley I, Mantovani A, Maysushima K, Nomiyama H et al. ( 2002 ) . Chemokine/Chemokine Receptor Nomenclature . Journal of Interferon & Cytokine Research vol. 22 , ( 10 ) 1067 - 1068 .

Müller B, Peri G, Doni A, Perruchoud AP, Landmann R, Pasqualini F, Mantovani A ( 2002 ) . High circulating levels of the IL-1 type II decoy receptor in critically ill patients with sepsis: association of high decoy receptor levels with glucocorticoid administration . Journal of Leukocyte Biology vol. 72 , ( 4 ) 643 - 649 .

Menten P, Saccani A, Dillen C, Wuyts A, Struyf S, Proost P, Mantovani A, Wang JM et al. ( 2002 ) . Role of the autocrine chemokines MIP-1α and MIP-1β in the metastatic behavior of murine T cell lymphoma . Journal of Leukocyte Biology vol. 72 , ( 4 ) 780 - 789 .

Sica A, Saccani A, Mantovani A ( 2002 ) . Tumor-associated macrophages: a molecular perspective . International Immunopharmacology vol. 2 , ( 8 ) 1045 - 1054 .

Nauta AJ, Trouw LA, Daha MR, Tijsma O, Nieuwland R, Schwaeble WJ, Gingras AR, Mantovani A et al. ( 2002 ) . Direct binding of C1q to apoptotic cells and cell blebs induces complement activation . European Journal of Immunology vol. 32 , ( 6 ) 1726 - 1736 .

Napoleone E, Di Santo A, Bastone A, Peri G, Mantovani A, de Gaetano G, Donati MB, Lorenzet R ( 2002 ) . Long Pentraxin PTX3 Upregulates Tissue Factor Expression in Human Endothelial Cells . Arteriosclerosis Thrombosis and Vascular Biology vol. 22 , ( 5 ) 782 - 787 .

Rolph MS, Zimmer S, Bottazzi B, Garlanda C, Mantovani A, Hansson GK ( 2002 ) . Production of the Long Pentraxin PTX3 in Advanced Atherosclerotic Plaques . Arteriosclerosis Thrombosis and Vascular Biology vol. 22 , ( 5 ) e10 - e14 .

Bosisio D, Polentarutti N, Sironi M, Bernasconi S, Miyake K, Webb GR, Martin MU, Mantovani A et al. ( 2002 ) . Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-γ: a molecular basis for priming and synergism with bacterial lipopolysaccharide . Blood vol. 99 , ( 9 ) 3427 - 3431 .

Pruijt JFM, Verzaal P, van Os R, de Kruijf E-JFM, van Schie MLJ, Mantovani A, Vecchi A, Lindley IJD et al. ( 2002 ) . Neutrophils are indispensable for hematopoietic stem cell mobilization induced by interleukin-8 in mice . Proceedings of the National Academy of Sciences of the United States of America vol. 99 , ( 9 ) 6228 - 6233 .

Schutyser E, Struyf S, Proost P, Opdenakker G, Laureys G, Verhasselt B, Peperstraete L, Van de Putte I et al. ( 2002 ) . Identification of Biologically Active Chemokine Isoforms from Ascitic Fluid and Elevated Levels of CCL18/Pulmonary and Activation-regulated Chemokine in Ovarian Carcinoma* . Journal of Biological Chemistry vol. 277 , ( 27 ) 24584 - 24593 .

Luchetti MM, Piccinini G, Mantovani A, Peri G, Matteucci C, Pomponio G, Fratini M, Fraticelli P et al. ( 2002 ) . Expression and production of the long pentraxin PTX3 in rheumatoid arthritis (RA) . Clinical & Experimental Immunology vol. 119 , ( 1 ) 196 - 202 .

Locati M, Deuschle U, Massardi ML, Martinez FO, Sironi M, Sozzani S, Bartfai T, Mantovani A ( 2002 ) . Analysis of the Gene Expression Profile Activated by the CC Chemokine Ligand 5/RANTES and by Lipopolysaccharide in Human Monocytes . The Journal of Immunology vol. 168 , ( 7 ) 3557 - 3562 .

Mantovani A ( 2002 ) . Pentraxins . Wiley Encyclopedia of Molecular Medicine , Wiley

Dobrina A, Pausa M, Fischetti F, Bulla R, Vecile E, Ferrero E, Mantovani A, Tedesco F ( 2002 ) . Cytolytically inactive terminal complement complex causes transendothelial migration of polymorphonuclear leukocytes in vitro and in vivo . Blood vol. 99 , ( 1 ) 185 - 192 .

Muzio M, Mantovani A ( 2001 ) . The Toll receptor family . Allergy vol. 56 , ( 2 ) 103 - 108 .

Allavena P, Badolato R, Facchetti F, Vermi W, Paganin C, Luini W, Giliani S, Mazza C et al. ( 2001 ) . Monocytes from Wiskott‐Aldrich patients differentiate in functional mature dendritic cells with a defect in CD83 expression . European Journal of Immunology vol. 31 , ( 12 ) 3413 - 3421 .

Dentener MA, Creutzberg EC, Schols AM, Mantovani A, van't Veer C, Buurman WA, Wouters EF ( 2001 ) . Systemic anti-inflammatory mediators in COPD: increase in soluble interleukin 1 receptor II during treatment of exacerbations . Thorax vol. 56 , ( 9 )

Locati M, Riboldi E, Bonecchi R, Transidico P, Bernasconi S, Haribabu B, Morris AJ, Mantovani A et al. ( 2001 ) . Selective induction of phospholipase D1 in pathogen-activated human monocytes . Biochemical Journal vol. 358 , ( Pt 1 ) 119 - 125 .

LOCATI M, RIBOLDI E, BONECCHI R, TRANSIDICO P, BERNASCONI S, HARIBABU B, MORRIS AJ, MANTOVANI A et al. ( 2001 ) . Selective induction of phospholipase D1 in pathogen-activated human monocytes . Biochemical Journal vol. 358 , ( 1 ) 119 - 125 .

Ghia P, Transidico P, Veiga JP, Schaniel C, Sallusto F, Matsushima K, Sallan SE, Rolink AG et al. ( 2001 ) . Chemoattractants MDC and TARC are secreted by malignant B-cell precursors following CD40 ligation and support the migration of leukemia-specific T cells . Blood vol. 98 , ( 3 ) 533 - 540 .

Muller B, Peri G, Doni A, Torri V, Landmann R, Bottazzi B, Mantovani A ( 2001 ) . Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients . Critical Care Medicine vol. 29 , ( 7 ) 1404 - 1407 .

Ravizza T, Moneta D, Bottazzi B, Peri G, Garlanda C, Hirsch E, Richards GJ, Mantovani A et al. ( 2001 ) . Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration . Neuroscience vol. 105 , ( 1 ) 43 - 53 .

Scapini P, Laudanna C, Pinardi C, Allavena P, Mantovani A, Sozzani S, Cassatella MA ( 2001 ) . Neutrophils produce biologically active macrophage inflammatory protein‐3α (MIP‐3α) / CCL20 and MIP‐3β / CCL19 . European Journal of Immunology vol. 31 , ( 7 ) 1981 - 1988 .

Mantovani A, Locati M, Vecchi A, Sozzani S, Allavena P ( 2001 ) . Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines . Trends in Immunology vol. 22 , ( 6 ) 328 - 336 .

Boglioni FV, Metra M, Locati M, Nodari S, Bontempi L, Garbellini M, Doni A, Peri G et al. ( 2001 ) . Role of inflammation mediators in the pathogenesis of heart failure . Giornale italiano di cardiologia (2006) vol. 2 , ( 6 ) 628 - 633 .

Fraticelli P, Sironi M, Bianchi G, D’Ambrosio D, Albanesi C, Stoppacciaro A, Chieppa M, Allavena P et al. ( 2001 ) . Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses . Journal of Clinical Investigation vol. 107 , ( 9 ) 1173 - 1181 .

Mantovani A, Garlanda C ( 2001 ) . Endothelial Cells: Immunological Aspects . Encyclopedia of Life Sciences , Wiley

Montalto P, Vlachogiannakos J, Teixeira R, Patch D, Peri G, Mantovani A, Burroughs AK ( 2001 ) . Long pentraxin PTX3: a potential new marker for infection in cirrhosis? . Journal of Hepatology . vol. 34 ,

Montalto P, Vlachogiannakos J, Teixeira R, Cox D, Peri G, Mantovani A, Burroughs AK ( 2001 ) . Raised levels of long pentraxin PTX3 are associated with the presence of a heparin effect in infected cirrhotics . Journal of Hepatology . vol. 34 ,

Muzio M, Mantovani A ( 2001 ) . Toll-like receptors (TLRs) signalling and expression pattern . Innate Immunity vol. 7 , ( 4 ) 297 - 300 .

Vulcano M, Albanesi C, Stoppacciaro A, Bagnati R, D'Amico G, Struyf S, Transidico P, Bonecchi R et al. ( 2001 ) . Dendritic cells as a major source of macrophage‐derived chemokine/CCL22 in vitro and in vivo . European Journal of Immunology vol. 31 , ( 3 ) 812 - 822 .

Ricotta D, Alessandri G, Pollara C, Fiorentini S, Favilli F, Tosetti M, Mantovani A, Grassi M et al. ( 2001 ) . Adult human heart microvascular endothelial cells are permissive for non-lytic infection by human cytomegalovirus . Cardiovascular Research vol. 49 , ( 2 ) 440 - 448 .

Balkwill F ( 2001 ) . Inflammation and cancer: back to Virchow? . The Lancet vol. 357 , ( 9255 ) 539 - 545 .

Sozzani S, Allavena P, Mantovani A ( 2001 ) . Chapter 15 Dendritic cells and chemokines . Dendritic Cells , Elsevier

Gerli R, Monti D, Bistoni O, Mazzone AM, Peri G, Cossarizza A, Di Gioacchino M, Cesarotti MEF et al. ( 2001 ) . Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians . Mechanisms of Ageing and Development vol. 121 , ( 1-3 ) 37 - 46 .

Luini W, D’Amico G, Bernasconi S, Allavena P, Mantovani A, Sozzani S ( 2001 ) . Chemotaxis of In Vitro Cultured Human Dendritic Cells . Methods In Molecular Medicine vol. 64 , 307 - 312 .

Fazzini F, Peri G, Doni A, Dell'Antonio G, Dal Cin E, Bozzolo E, D'Auria F, Praderio L et al. ( 2001 ) . PTX3 in small‐vessel vasculitides: An independent indicator of disease activity produced at sites of inflammation . Arthritis & Rheumatism vol. 44 , ( 12 ) 2841 - 2850 .

Locati M, Riboldi E, Otero K, Martinez FO, Riva F, Perrier P, Baviera S, Signorelli P et al. ( 2001 ) . Regulation of the Chemokine System at the Level of Chemokine Receptor Expression and Signaling Activity . Immunobiology vol. 204 , ( 5 ) 536 - 542 .

Bianchi G, D’Amico G, Sozzani S, Mantovani A, Allavena P ( 2001 ) . Transendothelial Migration and Reverse Transmigration of In Vitro Cultured Human Dendritic Cells . Methods In Molecular Medicine vol. 64 , 325 - 330 .

Rovere P, Peri G, Fazzini F, Bottazzi B, Doni A, Bondanza A, Zimmermann VS, Garlanda C et al. ( 2000 ) . The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells . Blood vol. 96 , ( 13 ) 4300 - 4306 .

D'Amico G, Frascaroli G, Bianchi G, Transidico P, Doni A, Vecchi A, Sozzani S, Allavena P et al. ( 2000 ) . Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys . Nature Immunology vol. 1 , ( 5 ) 387 - 391 .

Muzio M, Polentarutti N, Bosisio D, Kumar M, Mantovani A ( 2000 ) . Toll like receptor family and signaling pathway . Biochemical Society Transactions vol. 28 , ( 5 ) a489 - a489 .

Muzio M, Polentarutti N, Bosisio D, Kumar PPM, Mantovani A ( 2000 ) . Toll-like receptor family and signalling pathway . Biochemical Society Transactions vol. 28 , ( 5 ) 563 - 566 .

Mantovani A ( 2000 ) . Investigating T-cell memory . Nature vol. 407 , ( 6800 ) 40 - 40 .

Vicenzi E, Alfano M, Ghezzi S, Gatti A, Veglia F, Lazzarin A, Sozzani S, Mantovani A et al. ( 2000 ) . Divergent regulation of HIV-1 replication in PBMC of infected individuals by CC chemokines: suppression by RANTES, MIP-1α, and MCP-3, and enhancement by MCP-1 . Journal of Leukocyte Biology vol. 68 , ( 3 ) 405 - 412 .

Sozzani S, Bonecchi R, D'Amico G, Frascaroli G, Vecchi A, Allavena P, Mantovani A ( 2000 ) . In vitro and in vivo regulation of chemokine receptors . European Cytokine Network vol. 11 , ( 3 ) 502 - 503 .

Agnello D, Carvelli L, Muzio V, Villa P, Bottazzi B, Polentarutti N, Mennini T, Mantovani A et al. ( 2000 ) . Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: relation to inflammatory cytokines and modulation by dexamethasone and rolipram . Journal of Neuroimmunology vol. 109 , ( 2 ) 105 - 111 .

Mantovani A ( 2000 ) . Inflammatory cytokines . Recenti Progressi in Medicina vol. 91 , ( 9 ) 422 - 424 .

Mantovani A, Gray PA, Van Damme J, Sozzani S ( 2000 ) . Macrophage-derived chemokine (MDC) . Journal of Leukocyte Biology vol. 68 , ( 3 ) 400 - 404 .

Marone G, Aiuti F, Mantovani A ( 2000 ) . The Italian federation of immunological societies . Immunology Letters vol. 73 , 51 - 53 .

Muzio M, Polntarutti N, Bosisio D, Prahladan MK, Mantovani A ( 2000 ) . Toll like receptor family (TLT) and signalling pathway . European Cytokine Network vol. 11 , ( 3 ) 489 - 490 .

Bessis N, Guéry L, Mantovani A, Vecchi A, Sims JE, Fradelizi D, Boissier M ( 2000 ) . The type II decoy receptor of IL‐1 inhibits murine collagen‐induced arthritis . European Journal of Immunology vol. 30 , ( 3 ) 867 - 875 .

Peri G, Introna M, Corradi D, Iacuitti G, Signorini S, Avanzini F, Pizzetti F, Maggioni AP et al. ( 2000 ) . PTX3, A Prototypical Long Pentraxin, Is an Early Indicator of Acute Myocardial Infarction in Humans . Circulation vol. 102 , ( 6 ) 636 - 641 .

Cota M, Mengozzi M, Vicenzi E, Panina-Bordignon P, Sinigaglia F, Transidico P, Sozzani S, Mantovani A et al. ( 2000 ) . Selective inhibition of HIV replication in primary macrophages but not T lymphocytes by macrophage-derived chemokine . Proceedings of the National Academy of Sciences of the United States of America vol. 97 , ( 16 ) 9162 - 9167 .

Mantovani A, Garlanda C ( 2000 ) . Cytokine regulation of endothelial cell function: New molecules in an old paradigm . Atherosclerosis vol. 151 , ( 1 )

Polentarutti N, Bottazzi B, Di Santo E, Blasi E, Agnello D, Ghezzi P, Introna M, Bartfai T et al. ( 2000 ) . Inducible expression of the long pentraxin PTX3 in the central nervous system . Journal of Neuroimmunology vol. 106 , ( 1-2 ) 87 - 94 .

Romano M, Diomede L, Sironi M, Massimiliano L, Sottocorno M, Polentarutti N, Guglielmotti A, Albani D et al. ( 2000 ) . Inhibition of Monocyte Chemotactic Protein-1 Synthesis by Statins . Laboratory Investigation vol. 80 , ( 7 ) 1095 - 1100 .

Orlando S, Polentarutti N, Mantovani A ( 2000 ) . SELECTIVITY RELEASE OF THE TYPE II DECOY IL-1 RECEPTOR . Cytokine vol. 12 , ( 7 ) 1001 - 1006 .

Muzio M, Bosisio D, Polentarutti N, D’amico G, Stoppacciaro A, Mancinelli R, Veer CV, Penton-Rol G et al. ( 2000 ) . Differential Expression and Regulation of Toll-Like Receptors (TLR) in Human Leukocytes: Selective Expression of TLR3 in Dendritic Cells . The Journal of Immunology vol. 164 , ( 11 ) 5998 - 6004 .

Wymann MP, Sozzani S, Altruda F, Mantovani A, Hirsch E ( 2000 ) . Lipids on the move: phosphoinositide 3-kinases in leukocyte function . Trends in Immunology vol. 21 , ( 6 ) 260 - 264 .

Jensen LE, Muzio M, Mantovani A, Whitehead AS ( 2000 ) . IL-1 Signaling Cascade in Liver Cells and the Involvement of a Soluble Form of the IL-1 Receptor Accessory Protein . The Journal of Immunology vol. 164 , ( 10 ) 5277 - 5286 .

Sozzani S, Allavena P, Vecchi A, Mantovani A ( 2000 ) . Chemokines and Dendritic Cell Traffic . Journal of Clinical Immunology vol. 20 , ( 3 ) 151 - 160 .

Iellem A, Colantonio L, Bhakta S, Sozzani S, Mantovani A, Sinigaglia F, D'Ambrosio D ( 2000 ) . Inhibition by IL‐12 and IFN‐α of I‐309 and macrophage‐derived chemokine production upon TCR triggering of human Th1 cells . European Journal of Immunology vol. 30 , ( 4 ) 1030 - 1039 .

Bonecchi R, Facchetti F, Dusi S, Luini W, Lissandrini D, Simmelink M, Locati M, Bernasconi S et al. ( 2000 ) . Induction of Functional IL-8 Receptors by IL-4 and IL-13 in Human Monocytes . The Journal of Immunology vol. 164 , ( 7 ) 3862 - 3869 .

Mantovani A ( 2000 ) . Reply to Cohen . Trends in Immunology vol. 21 , ( 4 )

Muzio M, Polentarutti N, Bosisio D, Prahladan MKP, Mantovani A ( 2000 ) . Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes . Journal of Leukocyte Biology vol. 67 , ( 4 ) 450 - 456 .

Saccani A, Saccani S, Orlando S, Sironi M, Bernasconi S, Ghezzi P, Mantovani A, Sica A ( 2000 ) . Redox regulation of chemokine receptor expression . Proceedings of the National Academy of Sciences of the United States of America vol. 97 , ( 6 ) 2761 - 2766 .

Sozzani S, Allavena P, Vecchi A, Van Damme J, Mantovani A ( 2000 ) . Chemokine receptors: interaction with HIV-1 and viral-encoded chemokines . European Journal of Pharmaceutical Sciences vol. 74 , ( 2-3 ) 305 - 312 .

Sironi M, Massimiliano L, Transidico P, Pinza M, Sozzani S, Mantovani A, Vecchi A ( 2000 ) . Differential effect of benzydamine on pro- versus anti-inflammatory cytokine production: lack of inhibition of interleukin-10 and interleukin-1 receptor antagonist . International Journal of Clinical & Laboratory Research vol. 30 , ( 1 ) 17 - 19 .

Scarpino S, Stoppacciaro A, Ballerini F, Marchesi M, Prat M, Stella MC, Sozzani S, Allavena P et al. ( 2000 ) . Papillary Carcinoma of the Thyroid Hepatocyte Growth Factor (HGF) Stimulates Tumor Cells to Release Chemokines Active in Recruiting Dendritic Cells . American Journal Of Pathology vol. 156 , ( 3 ) 831 - 837 .

Muzio M, Mantovani A ( 2000 ) . Toll-like receptors . Microbes and Infection vol. 2 , ( 3 ) 251 - 255 .

Hirsch E, Katanaev VL, Garlanda C, Azzolino O, Pirola L, Silengo L, Sozzani S, Mantovani A et al. ( 2000 ) . Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation . Science vol. 287 , ( 5455 ) 1049 - 1053 .

Sica A, Saccani A, Bottazzi B, Polentarutti N, Vecchi A, Van Damme J, Mantovani A ( 2000 ) . Autocrine Production of IL-10 Mediates Defective IL-12 Production and NF-κB Activation in Tumor-Associated Macrophages . The Journal of Immunology vol. 164 , ( 2 ) 762 - 767 .

Sica A, Saccani A, Bottazzi B, Bernasconi S, Gaetano B, Fei F, Scotton C, Balkwill F ( 2000 ) . Defective Expression of the Monocyte Chemotactic Protein-1 Receptor CCR2 in Macrophages Associated with Human Ovarian Carcinoma . The Journal of Immunology vol. 164 , ( 2 ) 733 - 738 .

Coletta I, Soldo L, Polentarutti N, Mancini F, Guglielmotti A, Pinza M, Mantovani A, Milanese C ( 2000 ) . Selective Induction of MCP-1 in Human Mesangial Cells by the IL-6/sIL-6R Complex . Experimental Nephrology vol. 8 , ( 1 ) 37 - 43 .

Sozzani S, Allavena P, Vecchi A, Van Damme J, Mantovani A ( 2000 ) . Chemokine receptors: interaction with HIV-1 and viral-encoded chemokines . Pharmacochemistry Library vol. 31 , 305 - 312 .

Cota M, Kleinschmidt A, Ceccherini-Silberstein F, Aloisi F, Mengozzi M, Mantovani A, Brack-Werner R, Poli G ( 2000 ) . Upregulated expression of interleukin-8, RANTES and chemokine receptors in human astrocytic cells infected with HIV-1 . Journal of NeuroVirology vol. 6 , ( 1 ) 75 - 83 .

Garlanda C, Mantovani A ( 1999 ) . Cytokines and Adhesion Molecules in Mesothelial Cell Pathophysiology . Sepsis vol. 3 , ( 4 ) 271 - 283 .

Penton-Rol G, Cota M, Polentarutti N, Luini W, Bernasconi S, Borsatti A, Sica A, LaRosa GJ et al. ( 1999 ) . Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 89.6 in monocytes exposed to glucocorticoid hormones . The Journal of Immunology vol. 163 , ( 6 ) 3524 - 3529 .

Sironi M, Guglielmotti A, Polentarutti N, Fioretti F, Milanese C, Romano M, Vigini C, Coletta I et al. ( 1999 ) . A small synthetic molecule capable of preferentially inhibiting the production of the CC chemokine monocyte chemotactic protein-1 . European Cytokine Network vol. 10 , ( 3 ) 437 - 442 .

Vecchi A, Massimiliano L, Ramponi S, Luini W, Bernasconi S, Bonecchi R, Allavena P, Parmentier M et al. ( 1999 ) . Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells . Journal of Leukocyte Biology vol. 66 , ( 3 ) 489 - 494 .

Mantovani A ( 1999 ) . The chemokine system: redundancy for robust outputs . Trends in Immunology vol. 20 , ( 6 ) 254 - 257 .

Foti M, Granucci F, Aggujaro D, Liboi E, Luini W, Minardi S, Mantovani A, Sozzani S et al. ( 1999 ) . Upon dendritic cell (DC) activation chemokines and chemokine receptor expression are rapidly regulated for recruitment and maintenance of DC at the inflammatory site . International Immunology vol. 11 , ( 6 ) 979 - 986 .

Mantovani A, Garlanda C ( 1999 ) . Cytokine activation of endothelial cells: New molecules in an old paradigm . Atherosclerosis . vol. 144 ,

RUCO LP, DE LAAT PAJM, MATTEUCCI C, BERNASCONI S, SCIACCA FM, VAN DER KWAST TH, HOOGSTEDEN HC, UCCINI S et al. ( 1999 ) . EXPRESSION OF ICAM‐1 AND VCAM‐1 IN HUMAN MALIGNANT MESOTHELIOMA . The Journal of Pathology vol. 179 , ( 3 ) 266 - 271 .

Zhang FX, Kirschning CJ, Mancinelli R, Faure E, Mantovani A, Rothe M, Muzio M, Arditi M ( 1999 ) . Bacterial Lipopolysaccharide (LPS) Activates NF-κB through Interleukin-1 (IL-1) Signaling Mediators in Cultured Human Endothelial Cells and Mononuclear Phagocytes . Pediatric Research . vol. 45 , 179 - 179 .

Mengozzi M, De Filippi C, Transidico P, Biswas P, Cota M, Ghezzi S, Vicenzi E, Mantovani A et al. ( 1999 ) . Human Immunodeficiency Virus Replication Induces Monocyte Chemotactic Protein-1 in Human Macrophages and U937 Promonocytic Cells . Blood vol. 93 , ( 6 ) 1851 - 1857 .

Muzio M, Polentarutti N, Facchetti F, Peri G, Doni A, Sironi M, Transidico P, Salmona M et al. ( 1999 ) . Characterization of type II intracellular IL‐1 receptor antagonist (IL‐1ra3): a depot IL‐1ra . European Journal of Immunology vol. 29 , ( 3 ) 781 - 788 .

Zhang FX, Kirschning CJ, Mancinelli R, Xu X-P, Jin Y, Faure E, Mantovani A, Rothe M et al. ( 1999 ) . Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes* . Journal of Biological Chemistry vol. 274 , ( 12 ) 7611 - 7614 .

Penton-Rol G, Orlando S, Polentarutti N, Bernasconi S, Muzio M, Introna M, Mantovani A ( 1999 ) . Bacterial lipopolysaccharide causes rapid shedding, followed by inhibition of mRNA expression, of the IL-1 type II receptor, with concomitant up-regulation of the type I receptor and induction of incompletely spliced transcripts . The Journal of Immunology vol. 162 , ( 5 ) 2931 - 2938 .

Proost P, Struyf S, Schols D, Opdenakker G, Sozzani S, Allavena P, Mantovani A, Augustyns K et al. ( 1999 ) . Truncation of Macrophage-derived Chemokine by CD26/ Dipeptidyl-Peptidase IV beyond Its Predicted Cleavage Site Affects Chemotactic Activity and CC Chemokine Receptor 4 Interaction* . Journal of Biological Chemistry vol. 274 , ( 7 ) 3988 - 3993 .

Mantovani A, Allavena P, Garlanda C, Ramponi S, Paganini C, Vecchi A, Sozzani S ( 1999 ) . Chemokines and Chemokine Receptors . From Basic Immunology to Immune-Mediated Demyelination , Springer Nature

Mantovani A ( 1999 ) . Chemokines. Introduction and overview . vol. 72 ,

Sozzani S, Mantovani A, Allavena P ( 1999 ) . Control of dendritic cell migration by chemokines . Forum (Genoa, Italy) vol. 9 , ( 4 ) 325 - 338 .

Mantovani A, Garlanda C ( 1999 ) . Novel pathways for negative regulation of inflammatory cytokines centered on receptor expression . vol. 97 , 97 - 104 .

Bussolino F, Mantovani A ( 1999 ) . Role of Inflammatory Mediators in Angiogenesis . Antiangiogenic Agents in Cancer Therapy , Springer Nature

Mantovani A, Vecchi A, Sozzani S, Sica A, Allavena P ( 1999 ) . Tumors as a Paradigm for the In Vivo Role of Chemokines in Leukocyte Recruitment . Chemokines and Cancer , Springer Nature

Bonecchi R, Polentarutti N, Luini W, Borsatti A, Bernasconi S, Locati M, Power C, Proudfoot A et al. ( 1999 ) . Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-gamma in human neutrophils . The Journal of Immunology vol. 162 , ( 1 ) 474 - 479 .

Bussolino F, Mantovani A ( 1998 ) . Role of Inflammatory Mediators in Angiogenesis . Antiangiogenic Agents in Cancer Therapy , vol. 3 , Springer Nature

Allavena P, Piemonti L, Longoni D, Bernasconi S, Stoppacciaro A, Ruco L, Mantovani A ( 1998 ) . IL‐10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages . European Journal of Immunology vol. 28 , ( 1 ) 359 - 369 .

Bernardini G, Hedrick J, Sozzani S, Luini W, Spinetti G, Weiss M, Menon S, Zlotnik A et al. ( 1998 ) . Identification of the CC chemokines TARC and macrophage inflammatory protein‐1β as novel functional ligands for the CCR8 receptor . European Journal of Immunology vol. 28 , ( 2 ) 582 - 588 .

Polentarutti N, Picardi G, Basile A, Cenzuales S, Rivolta A, Matteucci C, Peri G, Mantovani A et al. ( 1998 ) . Interferon‐γ inhibits expression of the long pentraxin PTX3 in human monocytes . European Journal of Immunology vol. 28 , ( 2 ) 496 - 501 .

Dong QG, Graziani A, Garlanda C, de Calmanovici RW, Arese M, Soldi R, Vecchi A, Mantovani A et al. ( 1998 ) . Anti‐tumor activity of cytokines against opportunistic vascular tumors in mice . International Journal of Cancer vol. 65 , ( 5 ) 700 - 708 .

Wang JM, Chertov O, Proost P, Li J, Menton P, Xu L, Sozzani S, Mantovani A et al. ( 1998 ) . Purification and identification of chemokines potentially involved in kidney‐specific metastasis by a murine lymphoma variant: induction of migration and NFκB activation . International Journal of Cancer vol. 75 , ( 6 ) 900 - 907 .

Mantovani A, Garlanda C, Introna M, Vecchi A ( 1998 ) . Regulation of endothelial cell function by pro- and anti-inflammatory cytokines . Transplantation Proceedings vol. 30 , ( 8 ) 4239 - 4243 .

Sozzani S, Luini W, Bianchi G, Allavena P, Wells TNC, Napolitano M, Bernardini G, Vecchi A et al. ( 1998 ) . The Viral Chemokine Macrophage Inflammatory Protein-II Is a Selective Th2 Chemoattractant . Blood vol. 92 , ( 11 ) 4036 - 4039 .

D’Ambrosio D, Iellem A, Bonecchi R, Mazzeo D, Sozzani S, Mantovani A, Sinigaglia F ( 1998 ) . Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells . The Journal of Immunology vol. 161 , ( 10 ) 5111 - 5115 .

Bonecchi R, Sozzani S, Stine JT, Luini W, D'Amico G, Allavena P, Chantry D, Mantovani A ( 1998 ) . Divergent Effects of Interleukin-4 and Interferon-γ on Macrophage-Derived Chemokine Production: An Amplification Circuit of Polarized T Helper 2 Responses . Blood vol. 92 , ( 8 ) 2668 - 2671 .

Saccani S, Polentarutti N, Penton-Rol G, Sims JE, Mantovani A ( 1998 ) . DIVERGENT EFFECTS OF LPS ON EXPRESSION OF IL-1 RECEPTOR FAMILY MEMBERS IN MONONUCLEAR PHAGOCYTES IN VITRO AND IN VIVO . Cytokine vol. 10 , ( 10 ) 773 - 780 .

Luciani MG, Stoppacciaro A, Peri G, Mantovani A, Ruco LP ( 1998 ) . The monocyte chemotactic protein a (MCP-1) and interleukin 8 (IL-8) in Hodgkin's disease and in solid tumours . Molecular Pathology vol. 51 , ( 5 )

Struyf S, Proost P, Sozzani S, Mantovani A, Wuyts A, De Clercq E, Schols D, Van Damme J ( 1998 ) . Enhanced anti-HIV-1 activity and altered chemotactic potency of NH2-terminally processed macrophage-derived chemokine (MDC) imply an additional MDC receptor . The Journal of Immunology vol. 161 , ( 6 ) 2672 - 2675 .

Longoni D, Piemonti L, Bernasconi S, Mantovani A, Allavena P ( 1998 ) . Interleukin-10 increases mannose receptor expression and endocytic activity in monocyte-derived dendritic cells . International Journal of Clinical & Laboratory Research vol. 28 , ( 3 ) 162 - 169 .

van der Velden VH, Verheggen MM, Bernasconi S, Sozzani S, Naber BA, van der Linden-van Beurden CA, Hoogsteden HC, Mantovani A et al. ( 1998 ) . Interleukin-1beta and interferon-gamma differentially regulate release of monocyte chemotactic protein-1 and interleukin-8 by human bronchial epithelial cells . European Cytokine Network vol. 9 , ( 3 ) 269 - 277 .

Mantovani A, Allavena P, Vecchi A, Sozzani S ( 1998 ) . Regulation of chemokine receptor expression in dendritic cells . Research in Immunology vol. 149 , ( 7-8 ) 639 - 641 .

Mantovani A, Allavena P, Sozzani S ( 1998 ) . Regulation of chemokine receptors in mononuclear phagocytes versus dendritic cells and in the amplification of Th1 versus Th2 responses . European Cytokine Network vol. 9 , ( 3 Suppl ) 76 - 80 .

Sozzani S, Allavena P, D’Amico G, Luini W, Bianchi G, Kataura M, Imai T, Yoshie O et al. ( 1998 ) . Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties . The Journal of Immunology vol. 161 , ( 3 ) 1083 - 1086 .

Badolato R, Sozzani S, Malacarne F, Bresciani S, Fiorini M, Borsatti A, Albertini A, Mantovani A et al. ( 1998 ) . Monocytes from Wiskott-Aldrich patients display reduced chemotaxis and lack of cell polarization in response to monocyte chemoattractant protein-1 and formyl-methionyl-leucyl-phenylalanine . The Journal of Immunology vol. 161 , ( 2 ) 1026 - 1033 .

D'Amico G, Bianchi G, Bernasconi S, Bersani L, Piemonti L, Sozzani S, Mantovani A, Allavena P ( 1998 ) . Adhesion, Transendothelial Migration, and Reverse Transmigration of In Vitro Cultured Dendritic Cells . Blood vol. 92 , ( 1 ) 207 - 214 .

Cinque P, Vago L, Mengozzi M, Torri V, Ceresa D, Vicenzi E, Transidico P, Vagani A et al. ( 1998 ) . Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication . AIDS vol. 12 , ( 11 ) 1327 - 1332 .

Fioretti F, Fradelizi D, Stoppacciaro A, Ramponi S, Ruco L, Minty A, Sozzani S, Garlanda C et al. ( 1998 ) . Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (MCP-3) gene transfer: perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumor . The Journal of Immunology vol. 161 , ( 1 ) 342 - 346 .

Muzio M, Natoli G, Saccani S, Levrero M, Mantovani A ( 1998 ) . The Human Toll Signaling Pathway: Divergence of Nuclear Factor κB and JNK/SAPK Activation Upstream of Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6) . Journal of Experimental Medicine vol. 187 , ( 12 ) 2097 - 2101 .

Mantovani A, Allavena P, Vecchi A, Sozzani S, Mantovani A ( 1998 ) . Chemokines and chemokine receptors during activation and deactivation of monocytes and dendritic cells and in amplification of Th1 versus Th2 responses . International Journal of Clinical & Laboratory Research vol. 28 , ( 2 ) 77 - 82 .

Penton-Rol G, Polentarutti N, Luini W, Borsatti A, Mancinelli R, Sica A, Sozzani S, Mantovani A ( 1998 ) . Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-gamma . The Journal of Immunology vol. 160 , ( 8 ) 3869 - 3873 .

Presta M, Belleri M, Vecchi A, Hesselgesser J, Mantovani A, Horuk R ( 1998 ) . Noncompetitive, Chemokine-mediated Inhibition of Basic Fibroblast Growth Factor-induced Endothelial Cell Proliferation* . Journal of Biological Chemistry vol. 273 , ( 14 ) 7911 - 7919 .

Sozzani S, Ghezzi S, Iannolo G, Luini W, Borsatti A, Polentarutti N, Sica A, Locati M et al. ( 1998 ) . Interleukin 10 Increases CCR5 Expression and HIV Infection in Human Monocytes . Journal of Experimental Medicine vol. 187 , ( 3 ) 439 - 444 .

Vizler C, Rosato A, Calderazzo F, Quintieri L, Fruscella P, Wainstok de Calmanovici R, Mantovani A, Vecchi A et al. ( 1998 ) . Therapeutic effect of interleukin 12 on mouse haemangiosarcomas is not associated with an increased anti-tumour cytotoxic T-lymphocyte activity . British Journal of Cancer vol. 77 , ( 4 ) 656 - 662 .

Bonecchi R, Bianchi G, Bordignon PP, D'Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P et al. ( 1998 ) . Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s . Journal of Experimental Medicine vol. 187 , ( 1 ) 129 - 134 .

Colotta F, Ghezzi P, Mantovani A ( 1998 ) . 1. Interleukin 1 . Cytokines , Elsevier

Fioretti F, Dong QG, Fusco M, Vecchi A, Mantovani A ( 1998 ) . Antitumor Activity of IL-12 in a Mouse Opportunistic Vascular Tumor: Role of Immunocompetent Cells and Cytokines . Vascular Endothelium , Springer Nature

Mantovani A, Sica A, Saccani S, Orlando S, Polentarutti N, Allavena P, Sozzani S ( 1998 ) . Chapter 7 Regulation of Inflammatory Cytokine Receptor Expression by Pro- and Anti-Inflammatory Molecules . Asthma and Allergic Diseases , Elsevier

Mantovani A, Allavena P, Sozzani S ( 1998 ) . Chemokines: Attraction of dendritic cells and role in tumor immunobiology . Chemokines and Skin , Springer Nature

Mantovani A, Allavena P, Vecchi A, Dejana E, Sozzani S, Introna M ( 1998 ) . Cytokine Regulation of Endothelial Cell Function . NATO Science Series A: . 105 - 134 .

Mantovani A, Dejana E ( 1998 ) . Endothelium . Encyclopedia of Immunology , Elsevier

Biswas P, Delfanti F, Bernasconi S, Mengozzi M, Cota M, Polentarutti N, Mantovani A, Lazzarin A et al. ( 1998 ) . Interleukin-6 Induces Monocyte Chemotactic Protein-1 in Peripheral Blood Mononuclear Cells and in the U937 Cell Line . Blood vol. 91 , ( 1 ) 258 - 265 .

Sozzani S, Allavena P, Mantovani A ( 1998 ) . Molecules Involved in the Recruitment and Regulation of Tumor-Associated Macrophages . Nitric Oxide in Transplant Rejection and Anti-Tumor Defense , Springer Nature

Sozzani S, Longoni D, Bonecchi R, Luini W, Bersani L, D'Amico G, Borsatti A, Bussolino F et al. ( 1997 ) . Human monocyte‐derived and CD34+ cell‐derived dendritic cells express functional receptors for platelet activating factor . FEBS Letters vol. 418 , ( 1-2 ) 98 - 100 .

Sironi M, Milanese C, Vecchi A, Polenzani L, Guglielmotti A, Coletta I, Landolfi C, Soldo L et al. ( 1997 ) . Benzydamine inhibits the release of tumor necrosis factor-α and monocyte chemotactic protein-1 byCandida albicans-stimulated human peripheral blood cells . International Journal of Clinical & Laboratory Research vol. 27 , ( 2-4 ) 118 - 122 .

Vouret-Craviari V, Cenzuales S, Poli G, Mantovani A ( 1997 ) . EXPRESSION OF MONOCYTE CHEMOTACTIC PROTEIN-3 IN HUMAN MONOCYTES EXPOSED TO THE MYCOBACTERIAL CELL WALL COMPONENT LIPOARABINOMANNAN . Cytokine vol. 9 , ( 12 ) 992 - 998 .

Bottazzi B, Vouret-Craviari V, Bastone A, De Gioia L, Matteucci C, Peri G, Spreafico F, Pausa M et al. ( 1997 ) . Multimer Formation and Ligand Recognition by the Long Pentraxin PTX3 SIMILARITIES AND DIFFERENCES WITH THE SHORT PENTRAXINS C-REACTIVE PROTEIN AND SERUM AMYLOID P COMPONENT* . Journal of Biological Chemistry vol. 272 , ( 52 ) 32817 - 32823 .

Orlando S, Sironi M, Bianchi G, Drummond AH, Boraschi D, Yabes D, Mantovani A ( 1997 ) . Role of Metalloproteases in the Release of the IL-1 type II Decoy Receptor* . Journal of Biological Chemistry vol. 272 , ( 50 ) 31764 - 31769 .

Power CA, Church DJ, Meyer A, Alouani S, Proudfoot AEI, Clark-Lewis I, Sozzani S, Mantovani A et al. ( 1997 ) . Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3α from Lung Dendritic Cells . Journal of Experimental Medicine vol. 186 , ( 6 ) 825 - 835 .

Polentarutti N, Introna M, Sozzani S, Mancinelli R, Mantovani G, Mantovani A ( 1997 ) . Expression of monocyte chemotactic protein-3 in human monocytes and endothelial cells . European Cytokine Network vol. 8 , ( 3 ) 271 - 274 .

Penton Rol G, Polentarutti N, Sironi M, Saccani S, Introna M, Mantovani A ( 1997 ) . Gene transfer-mediated expression of physiological numbers of the type II decoy receptor in a myelomonocytic cellular context dampens the response to interleukin-1 . European Cytokine Network vol. 8 , ( 3 ) 265 - 269 .

Sozzani S, Luini W, Borsatti A, Polentarutti N, Zhou D, Piemonti L, D’Amico G, Power CA et al. ( 1997 ) . Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines . The Journal of Immunology vol. 159 , ( 4 ) 1993 - 2000 .

Dong QG, Bernasconi S, Lostaglio S, Wainstok De Calmanovici R, Martin-Padura I, Breviario F, Garlanda C, Ramponi S et al. ( 1997 ) . A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants . Arteriosclerosis Thrombosis and Vascular Biology vol. 17 , ( 8 ) 1599 - 1604 .

Garlanda C, Berthier R, Garin J, Stoppacciaro A, Ruco L, Vittet D, Gulino D, Matteucci C et al. ( 1997 ) . Characterization of MEC 14.7, a new monoclonal antibody recognizing mouse CD34: a useful reage for identifying and characterizing blood vessels and hematopoietic precursors . European Journal of Cell Biology vol. 73 , ( 4 ) 368 - 377 .

Di Santo E, Meazza C, Sironi M, Fruscella P, Mantovani A, Sipe JD, Ghezzi P ( 1997 ) . IL-13 inhibits TNF production but potentiates that of IL-6 in vivo and ex vivo in mice . The Journal of Immunology vol. 159 , ( 1 ) 379 - 382 .

Sozzani S, Introna M, Bernasconi S, Polentarutti N, Cinque P, Poli G, Sica A, Mantovani A ( 1997 ) . MCP-1 and CCR2 in HIV infection: regulation of agonist and receptor expression . Journal of Leukocyte Biology vol. 62 , ( 1 ) 30 - 33 .

Bussolino F, Mantovani A, Persico G ( 1997 ) . Molecular mechanisms of blood vessel formation . Trends in Biochemical Sciences vol. 22 , ( 7 ) 251 - 256 .

Allavena P, Giardina G, Bianchi G, Mantovani A ( 1997 ) . IL-15 is chemotactic for natural killer cells and stimulates their adhesion to vascular endothelium . Journal of Leukocyte Biology vol. 61 , ( 6 ) 729 - 735 .

Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW ( 1997 ) . Human Macrophage–derived Chemokine (MDC), a Novel Chemoattractant for Monocytes, Monocyte-derived Dendritic Cells, and Natural Killer Cells . Journal of Experimental Medicine vol. 185 , ( 9 ) 1595 - 1604 .

Tedesco F, Pausa M, Nardon E, Introna M, Mantovani A, Dobrina A ( 1997 ) . The Cytolytically Inactive Terminal Complement Complex Activates Endothelial Cells to Express Adhesion Molecules and Tissue Factor Procoagulant Activity . Journal of Experimental Medicine vol. 185 , ( 9 ) 1619 - 1628 .

Mantovani A, Bussolino F, Introna M ( 1997 ) . Cytokine regulation of endothelial cell function: from molecular level to the bedside . Trends in Immunology vol. 18 , ( 5 ) 231 - 240 .

Borsatti A, Bonecchi R, Locati M, Luini W, Fruscella P, Romano M, Mantovani A, Sozzani S ( 1997 ) . Role of secretory phospholipase A2 in the chemotactic response of neutrophils (PMN) to CXC and CC chemokines in vitro and in vivo . Immunology Letters vol. 56 ,

Albini A, Paglieri I, Orengo G, Carlone S, Aluigi MG, DeMarchi R, Matteucci C, Mantovani A et al. ( 1997 ) . The β-core fragment of human chorionic gonadotrophin inhibits growth of Kaposi's sarcoma-derived cells and a new immortalized Kaposi's sarcoma cell line . AIDS vol. 11 , ( 6 ) 713 - 721 .

Songia S, Mortellaro A, Taverna S, Fornasiero C, Scheiber EA, Erba E, Colotta F, Mantovani A et al. ( 1997 ) . Characterization of the new immunosuppressive drug undecylprodigiosin in human lymphocytes: retinoblastoma protein, cyclin-dependent kinase-2, and cyclin-dependent kinase-4 as molecular targets . The Journal of Immunology vol. 158 , ( 8 ) 3987 - 3995 .

Orlando S, Matteucci C, Fadlon EJ, Buurman WA, Bardella MT, Colotta F, Introna M, Mantovani A ( 1997 ) . TNF-alpha, unlike other pro- and anti-inflammatory cytokines, induces rapid release of the IL-1 type II decoy receptor in human myelomonocytic cells . The Journal of Immunology vol. 158 , ( 8 ) 3861 - 3868 .

Vanzulli S, Gazzaniga S, Braidot MF, Vecchi A, Mantovani A, Wainstok de Calmanovici R ( 1997 ) . Detection of endothelial cells by MEC 13.3 monoclonal antibody in mice mammary tumors . Biocell vol. 21 , ( 1 ) 39 - 46 .

Vouret-Craviari V, Matteucci C, Peri G, Poli G, Introna M, Mantovani A ( 1997 ) . Expression of a long pentraxin, PTX3, by monocytes exposed to the mycobacterial cell wall component lipoarabinomannan . Infection and Immunity vol. 65 , ( 4 ) 1345 - 1350 .

Polentarutti N, Allavena P, Bianchi G, Giardina G, Basile A, Sozzani S, Mantovani A, Introna M ( 1997 ) . IL-2-regulated expression of the monocyte chemotactic protein-1 receptor (CCR2) in human NK cells: characterization of a predominant 3.4-kilobase transcript containing CCR2B and CCR2A sequences . The Journal of Immunology vol. 158 , ( 6 ) 2689 - 2694 .

Sica A, Saccani A, Borsatti A, Power CA, Wells TNC, Luini W, Polentarutti N, Sozzani S et al. ( 1997 ) . Bacterial Lipopolysaccharide Rapidly Inhibits Expression of C–C Chemokine Receptors in Human Monocytes . Journal of Experimental Medicine vol. 185 , ( 5 ) 969 - 974 .

Basile A, Sica A, d'Aniello E, Breviario F, Garrido G, Castellano M, Mantovani A, Introna M ( 1997 ) . Characterization of the Promoter for the Human Long Pentraxin PTX3 ROLE OF NF-κB IN TUMOR NECROSIS FACTOR-α AND INTERLEUKIN-1β REGULATION* . Journal of Biological Chemistry vol. 272 , ( 13 ) 8172 - 8178 .

Introna M, Mantovani A ( 1997 ) . Early activation signals in endothelial cells. Stimulation by cytokines . Arteriosclerosis Thrombosis and Vascular Biology vol. 17 , ( 3 ) 423 - 428 .

Sola F, Gualandris A, Belleri M, Giuliani R, Coltrini D, Bastaki M, Tosatti MPM, Bonardi F et al. ( 1997 ) . Endothelial cells overexpressing basic fibroblast growth factor (FGF-2) induce vascular tumors in immunodeficient mice . Angiogenesis vol. 1 , ( 1 ) 102 - 116 .

Uccini S, Sirianni MC, Vincenzi L, Topino S, Stoppacciaro A, Lesnoni La Parola I, Capuano M, Masini C et al. ( 1997 ) . Kaposi's sarcoma cells express the macrophage-associated antigen mannose receptor and develop in peripheral blood cultures of Kaposi's sarcoma patients . American Journal Of Pathology vol. 150 , ( 3 ) 929 - 938 .

Romano M, Sironi M, Toniatti C, Polentarutti N, Fruscella P, Ghezzi P, Faggioni R, Luini W et al. ( 1997 ) . Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment . Immunity vol. 6 , ( 3 ) 315 - 325 .

Soldi R, Primo L, Brizzi MF, Sanavio F, Aglietta M, Polentarutti N, Pegoraro L, Mantovani A et al. ( 1997 ) . Activation of JAK2 in Human Vascular Endothelial Cells by Granulocyte-Macrophage Colony-Stimulating Factor . Blood vol. 89 , ( 3 ) 863 - 872 .

Vicenzi E, Bagnarelli P, Santagostino E, Ghezzi S, Alfano M, Sinnone MS, Fabio G, Turchetto L et al. ( 1997 ) . Hemophilia and nonprogressing human immunodeficiency virus type 1 infection . Blood vol. 89 , ( 1 ) 191 - 200 .

Allavena P, Piemonti L, Longoni D, Bernasconi S, Stoppacciaro A, Ruco L, Mantovani A ( 1997 ) . IL-10 Prevents the Generation of Dendritic Cells from CD14+ Blood Monocytes, Promotes the Differentiation to Mature Macrophages and Stimulates Endocytosis of FITC-dextran . Advances in Experimental Medicine and Biology vol. 417 , 323 - 327 .

Van Damme J, Struyf S, Wuyts A, Opdenakker G, Proost P, Allavena P, Sozzani S, Mantovani A ( 1997 ) . Isolation of human monocyte chemotactic proteins and study of their producer and responder cells by immunotests and bioassays . Methods in Enzymology vol. 287 , 109 - 127 .

Sozzani S, Zhou D, Locati M, Bernasconi S, Luini W, Mantovani A, O'Flaherty JT ( 1996 ) . Stimulating properties of 5-oxo-eicosanoids for human monocytes: synergism with monocyte chemotactic protein-1 and -3 . The Journal of Immunology vol. 157 , ( 10 ) 4664 - 4671 .

Bernasconi S, Cinque P, Peri G, Sozzani S, Crociati A, Torri W, Vicenzi E, Vago L et al. ( 1996 ) . Selective Elevation of Monocyte Chemotactic Protein-1 in the Cerebrospinal Fluid of AIDS Patients with Cytomegalovirus Encephalitis . Journal of Infectious Diseases vol. 174 , ( 5 ) 1098 - 1100 .

Mantovani A, Locati M, Allavena P, Sozzani S ( 1996 ) . CHAPTER 10 The Chemokine Superfamily: Crosstalk with the IL-1 System . Immunobiology vol. 195 , ( 4-5 ) 522 - 549 .

Giraudo E, Arese M, Toniatti C, Strasly M, Primo L, Mantovani A, Ciliberto G, Bussolini F ( 1996 ) . IL-6 is an in vitro and in vivo autocrine growth factor for middle T antigen-transformed endothelial cells . The Journal of Immunology vol. 157 , ( 6 ) 2618 - 2623 .

Sironi M, Pozzi P, Polentarutti N, Benigni F, Coletta I, Guglielmotti A, Milanese C, Ghezzi P et al. ( 1996 ) . INHIBITION OF INFLAMMATORY CYTOKINE PRODUCTION AND PROTECTION AGAINST ENDOTOXIN TOXICITY BY BENZIDAMINE . Cytokine vol. 8 , ( 9 ) 710 - 716 .

Meda L, Bernasconi S, Bonaiuto C, Sozzani S, Zhou D, Otvos L, Mantovani A, Rossi F et al. ( 1996 ) . Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells . The Journal of Immunology vol. 157 , ( 3 ) 1213 - 1218 .

Allavena P, Bianchi G, Giardina P, Polentarutti N, Zhou D, Introna M, Sozzani S, Mantovani A ( 1996 ) . Migratory Response of Human NK Cells to Monocyte-Chemotactic Proteins . Methods vol. 10 , ( 1 ) 145 - 149 .

Villa A, Sironi M, Macchi P, Matteucci C, Notarangelo LD, Vezzoni P, Mantovani A ( 1996 ) . Monocyte Function in a Severe Combined Immunodeficient Patient With a Donor Splice Site Mutation in the Jak3 Gene . Blood vol. 88 , ( 3 ) 817 - 823 .

Villa A, Sironi M, Macchi P, Matteucci C, Notarangelo L, Vezzoni P, Mantovani A ( 1996 ) . Monocyte function in a severe combined immunodeficient patient with a donor splice site mutation in the Jak3 gene . Blood vol. 88 , ( 3 ) 817 - 823 .

Sozzani S, Locati M, Allavena P, Van Damme J, Mantovani A ( 1996 ) . Chemokines: a superfamily of chemotactic cytokines . International Journal of Clinical & Laboratory Research vol. 26 , ( 2 ) 69 - 82 .

Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D ( 1996 ) . Migration of Human Monocytes in Response to Vascular Endothelial Growth Factor (VEGF) Is Mediated via the VEGF Receptor flt-1 . Blood vol. 87 , ( 8 ) 3336 - 3343 .

Re F, Sironi M, Muzio M, Matteucci C, Introna M, Orlando S, Penton-Rol G, Dower SK et al. ( 1996 ) . Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with anti-interleukin-1 function . Journal of Experimental Medicine vol. 183 , ( 4 ) 1841 - 1850 .

Colotta F, Saccani S, Giri JG, Dower SK, Sims JE, Introna M, Mantovani A ( 1996 ) . Regulated expression and release of the IL-1 decoy receptor in human mononuclear phagocytes . The Journal of Immunology vol. 156 , ( 7 ) 2534 - 2541 .

Introna M, Alles V, Castellano M, Picardi G, De Gioia L, Bottazzai B, Peri G, Breviario F et al. ( 1996 ) . Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sites . Blood vol. 87 , ( 5 ) 1862 - 1872 .

Mantovani A ( 1996 ) . Edward Jenner 200 years on . Nature Medicine vol. 2 , ( 3 ) 256 - 256 .

Locati M, Lamorte G, Luini W, Introna M, Bernasconi S, Mantovani A, Sozzani S ( 1996 ) . Inhibition of Monocyte Chemotaxis to C-C Chemokines by Antisense Oligonucleotide for Cytosolic Phospholipase A2 (∗) . Journal of Biological Chemistry vol. 271 , ( 11 ) 6010 - 6016 .

Mantovani A, Muzio M, Ghezzi P, Colotta F, Introna M ( 1996 ) . Negative regulators of the interleukin-1 system: receptor antagonists and a decoy receptor . International Journal of Clinical & Laboratory Research vol. 26 , ( 1 ) 7 - 14 .

Sambo P, Fadlon EJ, Sironi M, Matteucci C, Introna M, Mantovani A, Colotta F ( 1996 ) . Reactive Oxygen Intermediates Cause Rapid Release of the Interleukin-1 Decoy Receptor From Human Myelomonocytic Cells . Blood vol. 87 , ( 5 ) 1682 - 1686 .

Sambo P, Fadlon E, Sironi M, Matteucci C, Introna M, Mantovani A, Colotta F ( 1996 ) . Reactive oxygen intermediates cause rapid release of the interleukin-1 decoy receptor from human myelomonocytic cells . Blood vol. 87 , ( 5 ) 1682 - 1686 .

Giovannini M, Strippoli P, Serra M, Sironi M, Fincato G, Colotta F, Bonafe M, Biunno I et al. ( 1996 ) . Production of interleukin-6 by human osteoclast-like cells from giant cell tumor of bone . International Journal of Oncology vol. 8 , ( 2 ) 297 - 303 .

Sozzani S, Allavena P, Proost P, Van Damme J, Mantovani A ( 1996 ) . Chemokines as targets for pharmacological intervention . Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques , vol. 47 , Springer Nature

Sozzani S, Allavena P, Proost P, Van Damme J, Mantovani A ( 1996 ) . Chemokines as targets for pharmacological intervention . vol. 47 , 53 - 80 .

Introna M, Alles VV, Picardi G, Basile A, Matteucci C, Bottazzi B, Peri G, D’Aniello E et al. ( 1996 ) . Cytokine Activation of Endothelium: Cloning and Characterization of a New IL-1 Inducible Gene . NATO Science Series A: . 139 - 144 .

Allavena P, Bianchi G, Paganin C, Giardina G, Mantovani A ( 1996 ) . Regulation of adhesion and transendothelial migration of natural killer cells . Natural Immunity vol. 15 , ( 2-3 ) 107 - 116 .

Mantovani A ( 1996 ) . The cytokines: a world apart? . Assistenza infermieristica e ricerca : AIR vol. 15 , ( 1 ) 35 - 44 .

Noris M, Bernasconi S, Casiraghi F, Sozzani S, Gotti E, Remuzzi G, Mantovani A ( 1995 ) . Monocyte chemoattractant protein-1 is excreted in excessive amounts in the urine of patients with lupus nephritis . Laboratory Investigation vol. 73 , ( 6 ) 804 - 809 .

Sozzani S, Sallusto F, Luini W, Zhou D, Piemonti L, Allavena P, Van Damme J, Valitutti S et al. ( 1995 ) . Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines . The Journal of Immunology vol. 155 , ( 7 ) 3292 - 3295 .

Zhou D, Luini W, Bernasconi S, Diomede L, Salmona M, Mantovani A, Sozzani S ( 1995 ) . Phosphatidic Acid and Lysophosphatidic Acid Induce Haptotactic Migration of Human Monocytes (∗) . Journal of Biological Chemistry vol. 270 , ( 43 ) 25549 - 25556 .

Bizzarri C, Bertini R, Bossu P, Sozzani S, Mantovani A, Van Darnme J, Tagliabue A, Boraschi D ( 1995 ) . Single-Cell Analysis of Macrophage Chemotactic Protein-1-Regulated Cytosolic Ca2+ Increase in Human Adherent Monocytes . Blood vol. 86 , ( 6 ) 2388 - 2394 .

Muzio M, Polentarutti N, Sironi M, Poli G, De Gioia L, Introna M, Mantovani A, Colotta F ( 1995 ) . Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist . Journal of Experimental Medicine vol. 182 , ( 2 ) 623 - 628 .

Colotta F, Orlando S, Fadlon EJ, Sozzani S, Matteucci C, Mantovani A ( 1995 ) . Chemoattractants induce rapid release of the interleukin 1 type II decoy receptor in human polymorphonuclear cells . Journal of Experimental Medicine vol. 181 , ( 6 ) 2181 - 2186 .

Sozzani S, Locati M, Zhou D, Rieppi M, Luini W, Lamorte G, Bianchi G, Polentarutti N et al. ( 1995 ) . Receptors, signal transduction, and spectrum of action of monocyte chemotactic protein-1 and related chemokines . Journal of Leukocyte Biology vol. 57 , ( 5 ) 788 - 794 .

Negus RP, Stamp GW, Relf MG, Burke F, Malik ST, Bernasconi S, Balkwill FR ( 1995 ) . The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer . Journal of Clinical Investigation vol. 95 , ( 5 ) 2391 - 2396 .

Mantovani A, Bottazzi B, Sozzani S, Peri G, Allavena P, Dong QG, Vecchi A, Colotta F ( 1995 ) . Cytokine regulation of monocyte recruitment . Archivum Immunologiae et Therapiae Experimentalis vol. 43 , ( 2 ) 149 - 152 .

Duperray A, Mantovani A, Introna M, Dejana E ( 1995 ) . Endothelial cell regulation of leukocyte infiltration in inflammatory tissues . Mediators of Inflammation vol. 4 , ( 5 ) 322 - 330 .

Piemonti L, Bernasconi S, Luini W, Trobonjaca Z, Minty A, Allavena P, Mantovani A ( 1995 ) . IL-13 supports differentiation of dendritic cells from circulating precursors in concert with GM-CSF . European Cytokine Network vol. 6 , ( 4 ) 245 - 252 .

BERTINI R, LUINI W, SOZZANI S, BOTTAZZI B, RUGGIERO P, BORASCHI D, SAGGIORO D, CHIECO-BIANCHI L et al. ( 1995 ) . Identification of MIP-1α/LD78 as a Monocyte Chemoattractant Released by the HTLV-I-Transformed Cell Line MT4 . AIDS Research and Human Retroviruses vol. 11 , ( 1 ) 155 - 160 .

Ghigo D, Arese M, Todde R, Vecchi A, Silvagno F, Costamagna C, Dong QG, Alessio M et al. ( 1995 ) . Middle T antigen-transformed endothelial cells exhibit an increased activity of nitric oxide synthase . Journal of Experimental Medicine vol. 181 , ( 1 ) 9 - 19 .

Mantovani A, Mertelsman R, Schreiber H, Feldmann M, Mihich E ( 1995 ) . Selected Aspects of the Immunopharmacology of Cytokines . 373 - 380 .

Sozzani S, Agwu DE, Ellenburg MD, Locati M, Rieppi M, Rojas A, Mantovani A, McPhail LC ( 1994 ) . Activation of Phospholipase D by Interleukin-8 in Human Neutrophils . Blood vol. 84 , ( 11 ) 3895 - 3901 .

Colotta F, Dower SK, Sims JE, Mantovani A ( 1994 ) . The type II ‘decoy’ receptor: A novel regulatory pathway for interleukin 1 . Trends in Immunology vol. 15 , ( 12 ) 562 - 566 .

Sciacca FL, Stürzl M, Bussolino F, Sironi M, Brandstetter H, Zietz C, Zhou D, Matteucci C et al. ( 1994 ) . Expression of adhesion molecules, platelet-activating factor, and chemokines by Kaposi's sarcoma cells . The Journal of Immunology vol. 153 , ( 10 ) 4816 - 4825 .

Alles V, Bottazzi B, Peri G, Golay J, Introna M, Mantovani A ( 1994 ) . Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes . Blood vol. 84 , ( 10 ) 3483 - 3493 .

Bussolino F, Bocchietto E, Silvagno F, Soldi R, Arese M, Mantovani A ( 1994 ) . Actions of Molecules which Regulate Hemopoiesis on Endothelial Cells: Memoirs of Common Ancestors? . Pathology - Research and Practice vol. 190 , ( 9-10 ) 834 - 839 .

Allavena P, Paganin C, Zhou D, Bianchi G, Sozzani S, Mantovani A ( 1994 ) . Interleukin-12 Is Chemotactic for Natural Killer Cells and Stimulates Their Interaction With Vascular Endothelium . Blood vol. 84 , ( 7 ) 2261 - 2268 .

Allavena P, Paganin C, Zhou D, Bianchi G, Sozzani S, Mantovani A ( 1994 ) . Interleukin-12 is chemotactic for natural killer cells and stimulates their interaction with vascular endothelium . Blood vol. 84 , ( 7 ) 2261 - 2268 .

Sironi M, Sciacca FL, Matteucci C, Conni M, Vecchi A, Bernasconi S, Minty A, Caput D et al. ( 1994 ) . Regulation of Endothelial and Mesothelial Cell Function by Interleukin-13: Selective Induction of Vascular Cell Adhesion Molecule-1 and Amplification of Interleukin-6 Production . Blood vol. 84 , ( 6 ) 1913 - 1921 .

Muzio M, Polentarutti N, Sironi M, Mantovani A, Colotta F ( 1994 ) . Identification, cloning and functional characterization of a new form of intracellular IL-1 receptor antagonist . Cytokine vol. 6 , ( 5 )

Bottazzi B, Alles V, Peri G, Golay J, Introna M, Mantovani A ( 1994 ) . Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes . Cytokine vol. 6 , ( 5 )

Polentarutti N, Muzio M, Sironi M, Minty A, Caput D, Ferrara P, Mantovani A, Colotta F ( 1994 ) . Interleukin-13 induces the production of interleukin-1 receptor antagonist (IL-1RA) and the expression of the mRNA for the intracellular (keratinocyte) form of IL-1RA in human myelomonocytic cells . Cytokine vol. 6 , ( 5 )

Colotta F, Sironi M, Re F, Polentarutti N, Mantovani A ( 1994 ) . Overexpression of the IL-1 type II decoy receptor inhibits IL-1 activities . Cytokine vol. 6 , ( 5 )

Suzzani S, Zhou D, Bianchi G, Rieppi M, Luini W, Lamorte G, Allavena P, Mantovani A ( 1994 ) . Receptors and signaling mechanisms of monocyte chemotactic protein(MCP)-1, MCP-2 and MCP-3 in human monocytes and NK cells . Cytokine vol. 6 , ( 5 )

Sironi M, Sciacca FL, Matteucci C, Conni M, Vecchi A, Minty A, Caput D, Ferrara P et al. ( 1994 ) . Selective induction of vascular cell adhesion molecule-1 and amplification of IL-6 production by IL-13 in endothelial (EC) and mesothelial (MC) cells . Cytokine vol. 6 , ( 5 )

Garlanda C, Parravicini C, Sironi M, De Rossi M, de Calmanovici RW, Carozzi F, Bussolino F, Colotta F et al. ( 1994 ) . Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle-sized T antigen: implications for the pathogenesis of opportunistic vascular tumors . Proceedings of the National Academy of Sciences of the United States of America vol. 91 , ( 15 ) 7291 - 7295 .

di Celle PF, Carbone A, Marchis D, Zhou D, Sozzani S, Zupo S, Pini M, Mantovani A et al. ( 1994 ) . Cytokine Gene Expression in B-Cell Chronic Lymphocytic Leukemia: Evidence of Constitutive Interleukin-8 (IL-8) mRNA Expression and Secretion of Biologically Active IL-8 Protein . Blood vol. 84 , ( 1 ) 220 - 228 .

di Celle P, Carbone A, Marchis D, Zhou D, Sozzani S, Zupo S, Pini M, Mantovani A et al. ( 1994 ) . Cytokine gene expression in B-cell chronic lymphocytic leukemia: evidence of constitutive interleukin-8 (IL-8) mRNA expression and secretion of biologically active IL-8 protein . Blood vol. 84 , ( 1 ) 220 - 228 .

Mantovani A ( 1994 ) . Tumor-associated macrophages in neoplastic progression: a paradigm for the in vivo function of chemokines . Laboratory Investigation vol. 71 , ( 1 ) 5 - 16 .

Mantovani A, Colotta F, Sozzani S, Allavena P, Dejana E ( 1994 ) . Vasodilation in multistep paradigm of leucocyte extravasation . The Lancet vol. 343 , ( 8911 ) 1499 - 1500 .

Colotta F, Sciacca FL, Sironi M, Luini W, Rabiet MJ, Mantovani A ( 1994 ) . Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin . American Journal Of Pathology vol. 144 , ( 5 ) 975 - 985 .

Colotta F, Mantovani A ( 1994 ) . Induction of the interleukin-1 decoy recptor by gluccorticoids . Trends in Pharmacological Sciences vol. 15 , ( 5 ) 138 - 139 .

Mantovani A, Sozzani S ( 1994 ) . Chemokines . The Lancet vol. 343 , ( 8902 )

Muzio M, Re F, Sironi M, Polentarutti N, Minty A, Caput D, Ferrara P, Mantovani A et al. ( 1994 ) . Interleukin-13 Induces the Production of Interleukin-1 Receptor Antagonist (IL-lra) and the Expression of the mRNA for the Intracellular (Keratinocyte) Form of IL-lra in Human Myelomonocytic Cells . Blood vol. 83 , ( 7 ) 1738 - 1743 .

Colotta F, Re F, Muzio M, Polentarutti N, Minty A, Caput D, Ferrara P, Mantovani A ( 1994 ) . Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells . Journal of Biological Chemistry vol. 269 , ( 17 ) 12403 - 12406 .

Vecchi A, Garlanda C, Lampugnani MG, Resnati M, Matteucci C, Stoppacciaro A, Schnurch H, Risau W et al. ( 1994 ) . Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium . European Journal of Cell Biology vol. 63 , ( 2 ) 247 - 254 .

Sozzani S, Zhou D, Locati M, Rieppi M, Proost P, Magazin M, Vita N, van Damme J et al. ( 1994 ) . Receptors and transduction pathways for monocyte chemotactic protein-2 and monocyte chemotactic protein-3. Similarities and differences with MCP-1 . The Journal of Immunology vol. 152 , ( 7 ) 3615 - 3622 .

Paganin C, Matteucci C, Cenzuales S, Mantovani A, Allavena P ( 1994 ) . IL-4 inhibits binding and cytotoxicity of NK cells to vascular endothelium . Cytokine vol. 6 , ( 2 ) 135 - 140 .

Sozzani S, Rieppi M, Locati M, Zhou D, Bussolino F, Proost P, Vandamme J, Mantovani A ( 1994 ) . Synergism Between Platelet Activating Factor and C-C Chemokines for Arachidonate Release in Human Monocytes . Biochemical and Biophysical Research Communications vol. 199 , ( 2 ) 761 - 766 .

Martìn-Padura I, Bazzoni G, Zanetti A, Bernasconi S, Elices MJ, Mantovani A, Dejana E ( 1994 ) . A novel mechanism of colon carcinoma cell adhesion to the endothelium triggered by beta 1 integrin chain . Journal of Biological Chemistry vol. 269 , ( 8 ) 6124 - 6132 .

Locati M, Zhou D, Luini W, Evangelista V, Mantovani A, Sozzani S ( 1994 ) . Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines. Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxis . Journal of Biological Chemistry vol. 269 , ( 7 ) 4746 - 4753 .

Re F, Muzio M, De Rossi M, Polentarutti N, Giri JG, Mantovani A, Colotta F ( 1994 ) . The type II "receptor" as a decoy target for interleukin 1 in polymorphonuclear leukocytes: characterization of induction by dexamethasone and ligand binding properties of the released decoy receptor . Journal of Experimental Medicine vol. 179 , ( 2 ) 739 - 743 .

Mantovani A ( 1994 ) . Book review A. Epenetos Monoclonal antibodies 2. Applications in clinical oncology 1992 Chapman & Hall London/ Glasgow/New York/Tokyo/Melbourne/Madras 556 £95.00 . Annals of Oncology vol. 5 , ( 1 )

Introna M, Colotta F, Sozzani S, Dejana E, Mantovani A ( 1994 ) . Pro- and anti-inflammatory cytokines: interactions with vascular endothelium . Clinical and Experimental Rheumatology vol. 12 Suppl 10 , s19 - s23 .

Luini W, Sozzani S, Van Damme J, Mantovani A ( 1994 ) . Species-specificity of monocyte chemotactic protein-1 and -3 . Cytokine vol. 6 , ( 1 ) 28 - 31 .

Poli G, Wang JM, Ruco L, Rossini S, Biondi A, Mantovani A, Uccini S ( 1993 ) . Expression and modulation of a mononuclear phagocyte differentiation antigen (PAM-1) during in vitro maturation of peripheral blood monocytes . International Journal of Clinical & Laboratory Research vol. 23 , ( 1-4 ) 83 - 87 .

Introna M, Breviario F, d'Aniello EM, Golay J, Dejana E, Mantovani A ( 1993 ) . IL-1 inducible genes in human umbilical vein endothelial cells . European Heart Journal vol. 14 Suppl K , 78 - 81 .

Bussolino F, Colotta F, Bocchietto E, Guglielmetti A, Mantovani A ( 1993 ) . Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor: activities on endothelial cells . International Journal of Clinical & Laboratory Research vol. 23 , ( 1-4 )

Bianchi G, Sironi M, Ghibaudi E, Selvaggini C, Elices M, Allavena P, Mantovani A ( 1993 ) . Migration of natural killer cells across endothelial cell monolayers . The Journal of Immunology vol. 151 , ( 10 ) 5135 - 5144 .

Chirivi RG, Garofalo A, Padura IM, Mantovani A, Giavazzi R ( 1993 ) . Interleukin 1 receptor antagonist inhibits the augmentation of metastasis induced by interleukin 1 or lipopolysaccharide in a human melanoma/nude mouse system . Cancer Research vol. 53 , ( 20 ) 5051 - 5054 .

Klein E, Mantovani A ( 1993 ) . Action of natural killer cells and macrophages in cancer . Current Opinion in Immunology vol. 5 , ( 5 ) 714 - 718 .

Colotta F, Re F, Mantovani A ( 1993 ) . GRANULOCYTE TRANSFUSIONS FROM GRANULOCYTE COLONY-STIMULATING FACTOR-TREATED DONORS: ALSO A QUESTION OF CELL SURVIVAL? . Blood vol. 82 , ( 7 )

Colotta F, Re F, Mantovani A ( 1993 ) . Granulocyte transfusions from granulocyte colony-stimulating factor- treated donors: also a question of cell survival? [letter; comment] . Blood vol. 82 , ( 7 ) 2258 - 2258 .

Taraboletti G, Belotti D, Dejana E, Mantovani A, Giavazzi R ( 1993 ) . Endothelial cell migration and invasiveness are induced by a soluble factor produced by murine endothelioma cells transformed by polyoma virus middle T oncogene . Cancer Research vol. 53 , ( 16 ) 3812 - 3816 .

Introna M, Breviario F, d'Aniello E, Luchetti MM, Vidal V, Dejana E, Mantovani A ( 1993 ) . Cytokine regulation of endothelial cell function . Behring Institute Mitteilungen ( 92 ) 23 - 29 .

Colotta F, Re F, Muzio M, Bertini R, Polentarutti N, Sironi M, Giri JG, Dower SK et al. ( 1993 ) . Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4 . Science vol. 261 , ( 5120 ) 472 - 475 .

Sims JE, Gayle MA, Slack JL, Alderson MR, Bird TA, Giri JG, Colotta F, Re F et al. ( 1993 ) . Interleukin 1 signaling occurs exclusively via the type I receptor . Proceedings of the National Academy of Sciences of the United States of America vol. 90 , ( 13 ) 6155 - 6159 .

Mantovani A ( 1993 ) . Book review S. Baron Interferon. Principles and clinical applications 1992 The University of Texas Medical Branch Galveston . Annals of Oncology vol. 4 , ( 6 )

Colotta F, Bussolino F, Polentarutti N, Guglielmetti A, Sironi M, Bocchietto E, De Rossi M, Mantovani A ( 1993 ) . Differential Expression of the Common β and Specific α Chains of the Receptors for GM-CSF, IL-3, and IL-5 in Endothelial Cells . Experimental Cell Research vol. 206 , ( 2 ) 311 - 317 .

Colotta F, Sironi M, Borrè A, Pollicino T, Bernasconi S, Boraschi D, Mantovani A ( 1993 ) . Type II Interleukin-1 Receptor Is Not Expressed in Cultured Endothelial Cells and Is Not Involved in Endothelial Cell Activation . Blood vol. 81 , ( 5 ) 1347 - 1351 .

Colotta F, Sironi M, Borre A, Pollicino T, Bernasconi S, Boraschi D, Mantovani A ( 1993 ) . Type II interleukin-1 receptor is not expressed in cultured endothelial cells and is not involved in endothelial cell activation . Blood vol. 81 , ( 5 ) 1347 - 1351 .

Sozzani S, Molino M, Locati M, Luini W, Cerletti C, Vecchi A, Mantovani A ( 1993 ) . Receptor-activated calcium influx in human monocytes exposed to monocyte chemotactic protein-1 and related cytokines . The Journal of Immunology vol. 150 , ( 4 ) 1544 - 1553 .

Mantovani A, Bottazzi B, Sozzani S, Peri G, Allavena P, Vecchi A, Colotta F ( 1993 ) . Biological Significance and Therapeutic Potential of Tumor-Associated Leukocytes . 87 - 94 .

Mantovani A, Bottazzi B, Sozzani S, Peri G, Allavena P, Garlanda C, Vecchi A, Colotta F ( 1993 ) . Cytokine Regulation of Tumor-Associated Macrophages: Therapeutic Implications . Cancer Therapy , Springer Nature

Mantovani A, Bottazzi B, Sozzani S, Peri G, Allavena P, Dong QG, Vecchi A, Colotta F ( 1993 ) . Cytokine regulation of tumour-associated macrophages . Research in Immunology vol. 144 , ( 4 ) 280 - 283 .

Bottazzi A, Walter S, Govoni D, Colotta F, Mantovani A ( 1993 ) . Effect of Monocyte Chemotactic Cytokine Gene Transfer on Macrophage Infiltration, Growth and Metastatic Behaviour of a Murine Melanoma . The Chemokines , vol. 351 , Springer Nature

Sciacca FL, Colotta F, Sironi M, Luini W, Mantovani A ( 1993 ) . Expression of Monocyte Chemotactic Protein-1 (Mcp-1) by Monocytes and Endothelial Cells Exposed to Thrombin . The Chemokines , vol. 351 , Springer Nature

Bertini R, Luini W, Bottazzi B, Mackay AR, Boraschi D, Van Damme J, Mantovani A ( 1993 ) . Identification of a Novel Tumor-Derived Monocyte Chemotactic Factor: Relationship with Tissue Inhibitor of Metalloproteinase . The Chemokines , vol. 351 , Springer Nature

Specchia G, Erroi E, Colotta F, Bersani L, Pansini N, Mantovani A, Liso V ( 1993 ) . Interleukin-1 and Tumor Necrosis Factor Production in Acute Nonlymphoid Leukemia . Leukemias , Springer Nature

Introna M, Breviario F, d’Aniello E, Dejana E, Mantovani A ( 1993 ) . Modulation of Endothelial Cell Function by Cytokines . NATO Science Series A: . 107 - 114 .

Mantovani A, Sozzani S, Bottazzi B, Peri G, Sciacca FL, Locati M, Colotta F ( 1993 ) . Monocyte Chemotactic Protein-1 (MCP-1): Signal Transduction and Involvement in the Regulation of Macrophage Traffic in Normal and Neoplastic Tissues . Advances in Experimental Medicine and Biology vol. 351 , 47 - 54 .

Mantovani A ( 1993 ) . Nobel's day on recent advances in cancer research . Annals of Oncology vol. 4 , ( 1 ) 34 - 35 .

Sozzani S, Locati M, Molino M, Zhou D, Luini W, Mantovani A ( 1993 ) . Signal Transduction by Monocyte Chemotactic Protein-1 (MCP-1) and Cross-Desensitization with Other Members of the Chemokine-β Subfamily in Human Monocytes . The Chemokines , vol. 351 , Springer Nature

Mantovani A, Bottazzi B, Sozzani S, Peri G, Allavena P, Garlanda C, Vecchi A, Colotta F ( 1993 ) . Tumor-associated Macrophages: Cytokine Regulation and Therapeutic Implications . Molecular and Cell Biology Updates . 229 - 234 .

Lanfrancone L, Boraschi D, Ghiara P, Falini B, Grignani F, Peri G, Mantovani A, Pelicci P ( 1992 ) . Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage- CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1 . Blood vol. 80 , ( 11 ) 2835 - 2842 .

Colotta F, Re F, Polentarutti N, Sozzani S, Mantovani A ( 1992 ) . Modulation of Granulocyte Survival and Programmed Cell Death by Cytokines and Bacterial Products . Blood vol. 80 , ( 8 ) 2012 - 2020 .

Colotta F, Re F, Polentarutti N, Sozzani S, Mantovani A ( 1992 ) . Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products . Blood vol. 80 , ( 8 ) 2012 - 2020 .

Jonjić N, Peri G, Bernasconi S, Sciacca FL, Colotta F, Pelicci P, Lanfrancone L, Mantovani A ( 1992 ) . Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells . Journal of Experimental Medicine vol. 176 , ( 4 ) 1165 - 1174 .

Colotta F, Polentarutti N, Sironi M, Mantovani A ( 1992 ) . Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines . Journal of Biological Chemistry vol. 267 , ( 26 ) 18278 - 18283 .

Colotta F, Borré A, Sciacca FL, Sironi M, Sozzani S, Bottazzi B, Mantovani A ( 1992 ) . Regulation of phagocyte recruitment and activation by chemotactic cytokines . Pharmacological Research vol. 26 ,

Sironi M, Gadina M, Kankova M, Riganti F, Mantovani A, Zandalasini M, Ghezzi P ( 1992 ) . Diffferential sensitivity of in vivo TNF and IL-6 production to modulation by anti-inflammatory drugs in mice . International Journal of Immunopharmacology vol. 14 , ( 6 ) 1045 - 1050 .

Apiranthitou-Drogari M, Paganin C, Bernasconi S, Losa G, Maneo A, Colombo N, Mantovani A, Allavena P ( 1992 ) . In search of specific cytotoxic T lymphocytes infiltrating or accompanying human ovarian carcinoma . Cancer Immunology, Immunotherapy vol. 35 , ( 4 ) 289 - 295 .

Vittori E, Sciacca F, Colotta F, Mantovani A, Mattoli S ( 1992 ) . Protective effect of nedocromil sodium on the interleukin-1-induced production of interleukin-8 in human bronchial epithelial cells . The Journal of Allergy and Clinical Immunology vol. 90 , ( 1 ) 76 - 84 .

Bussolino F, Sironi M, Bocchietto E, Mantovani A ( 1992 ) . Synthesis of platelet-activating factor by polymorphonuclear neutrophils stimulated with interleukin-8 . Journal of Biological Chemistry vol. 267 , ( 21 ) 14598 - 14603 .

Arsura M, Introna M, Passerini F, Mantovani A, Golay J ( 1992 ) . B-myb antisense oligonucleotides inhibit proliferation of human hematopoietic cell lines . Blood vol. 79 , ( 10 ) 2708 - 2716 .

Mantovani A, Bussolino F, Dejana E ( 1992 ) . Cytokine regulation of endothelial cell function . The FASEB Journal vol. 6 , ( 8 ) 2591 - 2599 .

Jonjic N, Jílek P, Bernasconi S, Peri G, Martìn-Padura I, Cenzuales S, Dejana E, Mantovani A ( 1992 ) . Molecules involved in the adhesion and cytotoxicity of activated monocytes on endothelial cells . The Journal of Immunology vol. 148 , ( 7 ) 2080 - 2083 .

Peristeris P, Clark BD, Gatti S, Faggioni R, Mantovani A, Mengozzi M, Orencole SF, Sironi M et al. ( 1992 ) . N-Acetylcysteine and glutathione as inhibitors of tumor necrosis factor production . Cellular Immunology vol. 140 , ( 2 ) 390 - 399 .

Castellano M, Golay J, Mantovani A, Introna M ( 1992 ) . Detection of a transcriptional block in the first intron of the human c-myb gene . International Journal of Clinical & Laboratory Research vol. 22 , ( 1-4 ) 159 - 164 .

Dejana E, Martin-Padura I, Lauri D, Bernasconi S, Bani MR, Garofalo A, Giavazzi R, Magnani J et al. ( 1992 ) . Endothelial leukocyte adhesion molecule-1-dependent adhesion of colon carcinoma cells to vascular endothelium is inhibited by an antibody to Lewis fucosylated type I carbohydrate chain . Laboratory Investigation vol. 66 , ( 3 ) 324 - 330 .

Bottazzi B, Walter S, Govoni D, Colotta F, Mantovani A ( 1992 ) . Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma . The Journal of Immunology vol. 148 , ( 4 ) 1280 - 1285 .

Colotta F, Borré A, Wang JM, Tattanelli M, Maddalena F, Polentarutti N, Peri G, Mantovani A ( 1992 ) . Expression of a monocyte chemotactic cytokine by human mononuclear phagocytes . The Journal of Immunology vol. 148 , ( 3 ) 760 - 765 .

Riganti F, Sironi M, Kankova M, D'Incalci M, Spreafico F, Mantovani A, Vecchi A ( 1992 ) . The unique interaction with immunity of FCE 24517, an antitumor drug with a novel mode of action . International Journal of Immunopharmacology vol. 14 , ( 2 ) 239 - 251 .

Bertini R, Sironi M, Martin-Padura I, Colotta F, Rambaldi S, Bernasconi S, Ghezzi P, Haskill SJ et al. ( 1992 ) . Inhibitory effect of recombinant intracellular interleukin 1 receptor antagonist on endothelial cell activation . Cytokine vol. 4 , ( 1 ) 44 - 47 .

Colotta F, Sironi M, Borrè A, Luini W, Maddalena F, Mantovani A ( 1992 ) . Interleukin 4 amplifies monocyte chemotactic protein and interleukin 6 production by endothelial cells . Cytokine vol. 4 , ( 1 ) 24 - 28 .

Mantovani A, Bottazzi B, Colotta F, Sozzani S, Ruco L ( 1992 ) . The origin and function of tumor-associated macrophages . Trends in Immunology vol. 13 , ( 7 ) 265 - 270 .

Bussolino F, De Rossi M, Sica A, Colotta F, Wang JM, Bocchietto E, Padura IM, Bosia A et al. ( 1991 ) . Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokines . The Journal of Immunology vol. 147 , ( 7 ) 2122 - 2129 .

Sozzani S, Luini W, Molino M, Jílek P, Bottazzi B, Cerletti C, Matsushima K, Mantovani A ( 1991 ) . The signal transduction pathway involved in the migration induced by a monocyte chemotactic cytokine . The Journal of Immunology vol. 147 , ( 7 ) 2215 - 2221 .

Boraschi D, Rambaldi A, Sica A, Ghiara P, Colotta F, Wang JM, de Rossi M, Zoia C et al. ( 1991 ) . Endothelial Cells Express the Interleukin-1 Receptor Type I . Blood vol. 78 , ( 5 ) 1262 - 1267 .

Wang JM, Sica A, Peri G, Walter S, Padura IM, Libby P, Ceska M, Lindley I et al. ( 1991 ) . Expression of monocyte chemotactic protein and interleukin-8 by cytokine-activated human vascular smooth muscle cells . Arteriosclerosis Thrombosis and Vascular Biology vol. 11 , ( 5 ) 1166 - 1174 .

Bottazzi B, Walter S, Govoni D, Colotta F, Mantovani A ( 1991 ) . Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth and susceptibility to IL-2 therapy of a murine melanoma . Cytokine vol. 3 , ( 5 )

Kankova M, Luini W, Pedrazzoni M, Riganti F, Sironi M, Bottazzi B, Mantovani A, Vecchi A ( 1991 ) . Impairment of cytokine production in mice fed a vitamin D3-deficient diet . Immunology vol. 73 , ( 4 ) 466 - 471 .

Saggioro D, Wang JM, Sironi M, Luini W, Mantovani A, Chieco-Bianchi L ( 1991 ) . Chemoattractant(s) in Culture Supernatants of HTLV-I-Infected T-Cell Lines . AIDS Research and Human Retroviruses vol. 7 , ( 7 ) 571 - 577 .

Colotta F, Polentarutti N, Mantovani A ( 1991 ) . Differential expression of Raf-1 protooncogene in resting and activated human leukocyte populations . Experimental Cell Research vol. 194 , ( 2 ) 284 - 288 .

Gadina M, Bertini R, Mengozzi M, Zandalasini M, Mantovani A, Ghezzi P ( 1991 ) . Protective effect of chlorpromazine on endotoxin toxicity and TNF production in glucocorticoid-sensitive and glucocorticoid-resistant models of endotoxic shock . Journal of Experimental Medicine vol. 173 , ( 6 ) 1305 - 1310 .

Martìn-Padura I, Mortarini R, Lauri D, Bernasconi S, Sanchez-Madrid F, Parmiani G, Mantovani A, Anichini A et al. ( 1991 ) . Heterogeneity in human melanoma cell adhesion to cytokine activated endothelial cells correlates with VLA-4 expression . Cancer Research vol. 51 , ( 8 ) 2239 - 2241 .

Zoja C, Wang JM, Bettoni S, Sironi M, Renzi D, Chiaffarino F, Abboud HE, Van Damme J et al. ( 1991 ) . Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells . American Journal Of Pathology vol. 138 , ( 4 ) 991 - 1003 .

Bussolino F, Ziche M, Wang JM, Alessi D, Morbidelli L, Cremona O, Bosia A, Marchisio PC et al. ( 1991 ) . In vitro and in vivo activation of endothelial cells by colony-stimulating factors . Journal of Clinical Investigation vol. 87 , ( 3 ) 986 - 995 .

Fincato G, Polentarutti N, Sica A, Mantovani A, Colotta F ( 1991 ) . Expression of a Heat-Inducible Gene of the HSP70 Family in Human Myelomonocytic Cells: Regulation by Bacterial Products and Cytokines . Blood vol. 77 , ( 3 ) 579 - 586 .

RUSCONI F, PARIZZI F, GARLASCHI L, ASSAEL BM, SIRONI M, GHEZZI P, MANTOVANI A ( 1991 ) . Interleukin 6 activity in infants and children with bacterial meningitis . The Pediatric Infectious Disease Journal vol. 10 , ( 2 ) 117 - 121 .

Allavena P, Paganin C, Martin-Padura I, Peri G, Gaboli M, Dejana E, Marchisio PC, Mantovani A ( 1991 ) . Molecules and structures involved in the adhesion of natural killer cells to vascular endothelium . Journal of Experimental Medicine vol. 173 , ( 2 ) 439 - 448 .

Morgan JG, Pereira HA, Sukiennicki T, Spitznagel JK, Larrick JW, Forsdyke DR, Blum S, Sideris DP et al. ( 1991 ) . Abstracts . Chemotactic Cytokines , vol. 305 , Springer Nature

Amadori A, Zamarchi R, Veronese ML, Panozzo M, Barelli A, Borri A, Sironi M, Colotta F et al. ( 1991 ) . B cell activation during HIV-1 infection. II. Cell-to-cell interactions and cytokine requirement . The Journal of Immunology vol. 146 , ( 1 ) 57 - 62 .

Luini W, De Rossi M, Licciardello L, Colotta F, Mantovani A ( 1991 ) . Chemotactic cytokine gene expression and production induced in human monocytes by membrane proteoglycans from Klebsiella pneumoniae . International Journal of Immunopharmacology vol. 13 , ( 6 ) 631 - 637 .

Dejana E, Bazzoni G, Martin-Padura I, Walter S, Mantovani A ( 1991 ) . Endothelial Cells as Targets for and Producers of Cytokines . NATO Science Series A: . 79 - 85 .

Kankova M, Luini W, Pedrazzoni M, Riganti F, Sironi M, Bottazzi B, Mantovani A, Vecchi A ( 1991 ) . Inhibition of cytokine production by vitamin D3 deficiency . International Journal of Immunopharmacology vol. 13 , ( 6 )

Sironi M, Bussolino F, De Rossi M, Sica A, Colotta F, Wang JM, Alessi D, Padura IM et al. ( 1991 ) . Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokines . International Journal of Immunopharmacology vol. 13 , ( 6 )

Vecchi A, Riganti F, Sironi M, Kankova M, Spreafico F, Mantovani A ( 1991 ) . The complex interaction of the antitumoral FCE24517 with the immune system . International Journal of Immunopharmacology vol. 13 , ( 6 )

Allavena P, Biondi A, Rossi V, Rambaldi A, Bassan R, Barbui T, Mantovani A ( 1990 ) . Natural Killer Cells: Biology and Clinical Application . Karger Publishers

Bianchi M, Mantovani A, Erroi A, Dinarello CA, Ghezzi P ( 1990 ) . Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells . Inflammation Research vol. 31 , ( 3-4 ) 275 - 279 .

Wang JM, Walter S, Mantovani A ( 1990 ) . Re-evaluation of the chemotactic activity of tumour necrosis factor for monocytes . Immunology vol. 71 , ( 3 ) 364 - 367 .

Girasole G, Wang JM, Pedrazzoni M, Pioli G, Balotta C, Passeri M, Lazzarin A, Ridolfo A et al. ( 1990 ) . Augmentation of monocyte chemotaxis by 1 alpha,25-dihydroxyvitamin D3. Stimulation of defective migration of AIDS patients . The Journal of Immunology vol. 145 , ( 8 ) 2459 - 2464 .

Lampugnani MG, Colotta F, Polentarutti N, Pedenovi M, Mantovani A, Dejana E ( 1990 ) . Thrombin Induces c-fos Expression in Cultured Human Endothelial Cells by a Ca2+-Dependent Mechanism . Blood vol. 76 , ( 6 ) 1173 - 1180 .

Masotto C, Scatturin M, Caspani G, Mengozzi M, Sironi M, Ghezzi P, Mantovani A, Carenzi A ( 1990 ) . Differential effect of central and peripheral IL-1β administration on serum corticosterone and IL-6 levels and food and hater intake . Pharmacological Research vol. 22 ,

Giavazzi R, Garofalo A, Bani MR, Abbate M, Ghezzi P, Boraschi D, Mantovani A, Dejana E ( 1990 ) . Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice . Cancer Research vol. 50 , ( 15 ) 4771 - 4775 .

Bottazzi B, Nobili N, Mantovani A ( 1990 ) . Expression of c-fos proto-oncogene in tumor-associated macrophages . The Journal of Immunology vol. 144 , ( 12 ) 4878 - 4882 .

Zachariae CO, Anderson AO, Thompson HL, Appella E, Mantovani A, Oppenheim JJ, Matsushima K ( 1990 ) . Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line . Journal of Experimental Medicine vol. 171 , ( 6 ) 2177 - 2182 .

Colotta F, Polentarutti N, Staffico M, Fincato G, Mantovani A ( 1990 ) . Heat shock induces the transcriptional activation of c-fos protooncogene . Biochemical and Biophysical Research Communications vol. 168 , ( 3 ) 1013 - 1019 .

Wang JM, Taraboletti G, Matsushima K, Van Damme J, Mantovani A ( 1990 ) . Induction of haptotactic migration of melanoma cells by neutrophil activating protein/interleukin-8 . Biochemical and Biophysical Research Communications vol. 169 , ( 1 ) 165 - 170 .

De Simoni MG, Sironi M, De Luigi A, Manfridi A, Mantovani A, Ghezzi P ( 1990 ) . Intracerebroventricular injection of interleukin 1 induces high circulating levels of interleukin 6 . Journal of Experimental Medicine vol. 171 , ( 5 ) 1773 - 1778 .

Sica A, Wang JM, Colotta F, Dejana E, Mantovani A, Oppenheim JJ, Larsen CG, Zachariae COC et al. ( 1990 ) . Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor . The Journal of Immunology vol. 144 , ( 8 ) 3034 - 3038 .

Sica A, Matsushima K, Van Damme J, Wang JM, Polentarutti N, Dejana E, Colotta F, Mantovani A ( 1990 ) . IL-1 transcriptionally activates the neutrophil chemotactic factor/IL-8 gene in endothelial cells . Immunology vol. 69 , ( 4 ) 548 - 553 .

Bottazzi B, Erba E, Nobili N, Fazioli F, Rambaldi A, Mantovani A ( 1990 ) . A paracrine circuit in the regulation of the proliferation of macrophages infiltrating murine sarcomas . The Journal of Immunology vol. 144 , ( 6 ) 2409 - 2412 .

Peri G, Chiaffarino F, Bernasconi S, Padura IM, Mantovani A ( 1990 ) . Cytotoxicity of activated monocytes on endothelial cells . The Journal of Immunology vol. 144 , ( 4 ) 1444 - 1448 .

Lampugnani MG, Polentarutti N, Pedenovi M, Mantovani A, Dejana E, Colotta F ( 1990 ) . c-fos and c-myc Expression in human endothelial cells as a function of different culture conditions . Experimental Cell Research vol. 186 , ( 2 ) 381 - 384 .

Allavena P, Pirovano P, Bonazzi C, Colombo N, Mantovani A, D'Incalci M ( 1990 ) . In Vitro and In Vivo Effects of Cisplatin on the Generation of Lymphokine-Activated Killer Cells . Journal of the National Cancer Institute vol. 82 , ( 2 ) 139 - 142 .

Mantovani A ( 1990 ) . In support of IL-8 . Trends in Immunology vol. 11 , ( 10 )

Mantovani A, Vecchi A ( 1990 ) . Interaction of cancer chemotherapy agents with the mononuclear phagocyte system . Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques , vol. 35 , Springer Nature

Mantovani A, Vecchi A ( 1990 ) . Interaction of cancer chemotherapy agents with the mononuclear phagocyte system . vol. 35 , 487 - 519 .

Breviario F, Proserpio P, Bertocchi F, Lampugnani MG, Mantovani A, Dejana E ( 1990 ) . Interleukin-1 stimulates prostacyclin production by cultured human endothelial cells by increasing arachidonic acid mobilization and conversion . Arteriosclerosis An Official Journal of the American Heart Association Inc vol. 10 , ( 1 ) 129 - 134 .

Sironi M, Sica A, Riganti F, Licciardello L, Colotta F, Mantovani A ( 1990 ) . Interleukin-6 gene expression and production induced in human monocytes by membrane proteoglycans from Klebsiella pneumoniae . International Journal of Immunopharmacology vol. 12 , ( 4 ) 397 - 402 .

Mantovani A, Sica A, Colotta F, Dejana E ( 1990 ) . The role of cytokines as communication signals between leukocytes and endothelial cells . Progress in Clinical and Biological Research vol. 349 , 343 - 353 .

Mantovani A ( 1990 ) . Tumor-associated macrophages . Current Opinion in Immunology vol. 2 , ( 5 ) 689 - 692 .

Mantovani A, Dejana E ( 1989 ) . Cytokines as communication signals between leukocytes and endothelial cells . Trends in Immunology vol. 10 , ( 11 ) 370 - 375 .

Bussolino F, Wang JM, Turrini F, Alessi D, Ghigo D, Costamagna C, Pescarmona G, Mantovani A et al. ( 1989 ) . Stimulation of the Na+/H+ exchanger in human endothelial cells activated by granulocyte- and granulocyte-macrophage-colony-stimulating factor Evidence for a role in proliferation and migration* . Journal of Biological Chemistry vol. 264 , ( 31 ) 18284 - 18287 .

Bertani A, Polentarutti N, Sica A, Rambaldi A, Mantovani A, Colotta F ( 1989 ) . Expression of c-jun Protooncogene in Human Myelomonocytic Cells . Blood vol. 74 , ( 5 ) 1811 - 1816 .

Punturieri A, Santoni A, Ming WJ, Nobili N, Mantovani A, Bottazzi B ( 1989 ) . In vitro migration of rat large granular lymphocytes . Cellular Immunology vol. 123 , ( 2 ) 257 - 263 .

Biondi A, Allavena P, Rossi V, Bassan R, Barbui T, Champagne E, Mak TW, Minden MD et al. ( 1989 ) . T cell receptor delta gene organization and expression in normal and leukemic natural killer cells . The Journal of Immunology vol. 143 , ( 3 ) 1009 - 1014 .

Pioli G, Girasole G, Pedrazzoni M, Sansoni P, Erroi A, Davoli L, Ciotti G, Mantovani A et al. ( 1989 ) . Spontaneous release of interleukin-1 (IL-1) from medullary mononuclear cells of pagetic subjects . Calcified Tissue International vol. 45 , ( 4 ) 257 - 259 .

Biondi A, Champagne E, Rossi V, Giudici G, Cantu-Rajnoldi A, Masera G, Mantovani A, Mak TW et al. ( 1989 ) . T-Cell Receptor Delta Gene Rearrangement in Childhood T-Cell Acute Lymphoblastic Leukemia . Blood vol. 73 , ( 8 ) 2133 - 2138 .

Biondi A, Rossi V, Bassan R, Barbui T, Bettoni S, Sironi M, Mantovani A, Rambaldi A ( 1989 ) . Constitutive Expression of the Interleukin-6 Gene in Chronic Lymphocytic Leukemia . Blood vol. 73 , ( 5 ) 1279 - 1284 .

Allavena P, Damia G, Colombo T, Maggioni D, D'Incalci M, Mantovani A ( 1989 ) . Lymphokine-activated killer (LAK) and monocyte-mediated cytotoxicity on tumor cell lines resistant to antitumor agents . Cellular Immunology vol. 120 , ( 1 ) 250 - 258 .

Wang JM, Chen ZG, Cianciolo GJ, Snyderman R, Breviario F, Dejana E, Mantovani A ( 1989 ) . Production of a retroviral P15E-related chemotaxis inhibitor by IL-1-treated endothelial cells. A possible negative feedback in the regulation of the vascular response to monokines . The Journal of Immunology vol. 142 , ( 6 ) 2012 - 2017 .

Bussolino F, Wang JM, Defilippi P, Turrini F, Sanavio F, Edgell C-JS, Aglietta M, Arese P et al. ( 1989 ) . Granulocyte- and granulocyte– macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate . Nature vol. 337 , ( 6206 ) 471 - 473 .

Sironi M, Breviario F, Proserpio P, Biondi A, Vecchi A, Van Damme J, Dejana E, Mantovani A ( 1989 ) . IL-1 stimulates IL-6 production in endothelial cells . The Journal of Immunology vol. 142 , ( 2 ) 549 - 553 .

Allavena P, Erroi A, Pirelli A, Licciardello L, Mantovani A ( 1989 ) . Stimulation of cytotoxic and non-cytotoxic functions of natural killer cells by bacterial membrane proteoglycans and ribosomes . International Journal of Immunopharmacology vol. 11 , ( 1 ) 29 - 34 .

Mantovani A, Dejana E ( 1989 ) . The Role of Cytokines in the Symbiotic Relationship between Leukocytes and Vascular Endothelia . Vascular Endothelium , Springer Nature

Bottazzi B, Giavazzi R, Nobili N, Fazioli F, Mantovani A ( 1989 ) . The Role of Macrophages in the Regulation of Tumor Growth and Metastasis . Cancer Metastasis , Springer Nature

Pirelli A, Allavena P, Mantovani A ( 1988 ) . Activated adherent large granular lymphocytes/natural killer (LGL/NK) cells change their migratory behaviour . Immunology vol. 65 , ( 4 ) 651 - 653 .

Wang JM, Chen ZG, Colella S, Bonilla MA, Welte K, Bordignon C, Mantovani A ( 1988 ) . Chemotactic Activity of Recombinant Human Granulocyte Colony-Stimulating Factor . Blood vol. 72 , ( 5 ) 1456 - 1460 .

Wang J, Chen Z, Colella S, Bonilla M, Welte K, Bordignon C, Mantovani A ( 1988 ) . Chemotactic activity of recombinant human granulocyte colony- stimulating factor . Blood vol. 72 , ( 5 ) 1456 - 1460 .

Tagliabue A, Nencioni L, Mantovani A, Lazzarin A, Villa L, Romano M, Rossini S, Foppa CU et al. ( 1988 ) . Impairment of in vitro natural antibacterial activity in HIV-infected patients . The Journal of Immunology vol. 141 , ( 8 ) 2607 - 2611 .

Di Bello M, Lucchini V, Chiari S, Colleoni R, Colombo N, Mantovani A, Allavena P ( 1988 ) . DR antigen expression on ovarian carcinoma cells does not correlate with their capacity to elicit an autologous proliferative response . Cancer Immunology, Immunotherapy vol. 27 , ( 1 ) 63 - 68 .

Allavena P, Lo Presti P, Di Bello M, Lucchini V, Lissoni A, Zanetta G, Mangioni C, Mantovani A ( 1988 ) . Proliferative response of lymphocytes from ovarian cancer patients to autologous tumor cells . Cancer Immunology, Immunotherapy vol. 27 , ( 1 ) 69 - 76 .

Wang JM, Chen ZG, Colotta F, Mantovani A ( 1988 ) . Role of GM-CSF in phagocyte recruitment and regulation of c-fos protooncogene expression . Behring Institute Mitteilungen ( 83 ) 270 - 273 .

Wang JM, Griffin JD, Rambaldi A, Chen ZG, Mantovani A ( 1988 ) . Induction of monocyte migration by recombinant macrophage colony-stimulating factor . The Journal of Immunology vol. 141 , ( 2 ) 575 - 579 .

Colotta F, Lampugnani MG, Polentarutti N, Dejana E, Mantovani A ( 1988 ) . Interleukin-1 induces c-fos protooncogene expression in cultured human endothelial cells . Biochemical and Biophysical Research Communications vol. 152 , ( 3 ) 1104 - 1110 .

Poli G, Erroi A, Polentarutti N, Vago L, Luisetti M, Biondi A, Mantovani A ( 1988 ) . Defective chemotaxis of human alveolar macrophages . Clinical Immunology vol. 47 , ( 3 ) 282 - 288 .

Allavena P, Peri G, Di Bello M, Peccatori F, Chiaffarino F, Pirovano P, Mantovani A ( 1988 ) . Lymphocytes infiltrating ovarian carcinoma: modulation of functional activity by intraperitoneal treatment with biological response modifiers . Natural Immunity vol. 7 , ( 4 ) 230 - 238 .

Chen ZG, Bottazzi B, Wang JM, Mantovani A ( 1988 ) . Tumor-associated macrophages in metastasizing tumors . Advances in Experimental Medicine and Biology vol. 233 , 61 - 71 .

Bottazzi B, Chen Z-G, Polentarutti N, Chiaffarino F, Mantovani A, Colotta F ( 1987 ) . Protooncogene expression in normal and tumor-infiltrating phagocytes . Immunology Letters vol. 16 , ( 3-4 ) 311 - 313 .

Pelicci PG, Allavena P, Subar M, Rambaldi A, Pirelli A, Di Bello M, Barbui T, Knowles DM et al. ( 1987 ) . T cell receptor (alpha, beta, gamma) gene rearrangements and expression in normal and leukemic large granular lymphocytes/natural killer cells . Blood vol. 70 , ( 5 ) 1500 - 1508 .

Pirelli A, Allavena P, Rambaldi A, Di Bello M, Pirovano P, Peccatori F, Mantovani A ( 1987 ) . T-cell receptor gene rearrangements and expression in normal human large granular lymphocytes (LGL) and their pathological expansions . Cytotechnology vol. 1 , ( 1 ) 79 - 81 .

Colotta F, Polentarutti N, Wang JM, Mantovani A ( 1987 ) . c-Fos protooncogene expression in human normal peripheral blood leukocytes . Cytotechnology vol. 1 , ( 1 ) 61 - 64 .

Bersani L, Colotta F, Peri G, Mantovani A ( 1987 ) . Cytotoxic effector function of B lymphoblasts . The Journal of Immunology vol. 139 , ( 2 ) 645 - 648 .

Ghezzi P, Erroi A, Acero R, Salmona M, Mantovani A ( 1987 ) . Defective Production of Reactive Oxygen Intermediates by Tumor-Associated Macrophages Exposed to Phorbol Ester . Journal of Leukocyte Biology vol. 42 , ( 1 ) 84 - 90 .

Benomar A, Ming WJ, Taraboletti G, Ghezzi P, Balotta C, Cianciolo GJ, Snyderman R, Doré JF et al. ( 1987 ) . Chemotactic factor and P15E-related chemotaxis inhibitor in human melanoma cell lines with different macrophage content and tumorigenicity in nude mice . The Journal of Immunology vol. 138 , ( 7 ) 2372 - 2379 .

Colotta F, Wang JM, Polentarutti N, Mantovani A ( 1987 ) . Expression of c-fos protooncogene in normal human peripheral blood granulocytes . Journal of Experimental Medicine vol. 165 , ( 4 ) 1224 - 1229 .

Wang JM, Colella S, Allavena P, Mantovani A ( 1987 ) . Chemotactic activity of human recombinant granulocyte-macrophage colony-stimulating factor . Immunology vol. 60 , ( 3 ) 439 - 444 .

Ming WJ, Bersani L, Mantovani A ( 1987 ) . Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes . The Journal of Immunology vol. 138 , ( 5 ) 1469 - 1474 .

Garattini S, Guaitani A, Mantovani A ( 1987 ) . Effect of etidronate disodium on the interactions between malignancy and bone . The American Journal of Medicine vol. 82 , ( 2 ) 29 - 33 .

Dejana E, Breviario F, Erroi A, Bussolino F, Mussoni L, Gramse M, Pintucci G, Casali B et al. ( 1987 ) . Modulation of Endothelial Cell Functions by Different Molecular Species of Interleukin 1 . Blood vol. 69 , ( 2 ) 695 - 699 .

Mantovani A, Dejana E ( 1987 ) . Modulation of endothelial function by interleukin-1 A novel target for pharmacological intervention? . Biochemical Pharmacology vol. 36 , ( 3 ) 301 - 305 .

Biondi A, Poli G, Parravicini C, Molinari A, Mantovani A ( 1987 ) . Mononuclear Phagocyte Function in the Perinatal Period . Immunology of the Neonate , Springer Nature

Pomè G, Vitali E, Mantovani A, Panzeri E ( 1987 ) . Surgical treatment of the aberrant retroesophageal right subclavian artery in adults (dysphagia lusoria). Report of two new cases and review of the literature . The Journal of Cardiovascular Surgery vol. 28 , ( 4 ) 405 - 412 .

Peri G, Rossi V, Taraboletti G, Erroi A, Mantovani A ( 1986 ) . Ia antigen expression and IL-1 activity in murine tumour-associated macrophages . Immunology vol. 59 , ( 4 ) 527 - 533 .

Allavena P, Merendino A, Di Bello M, Pirelli A, Rossini S, Mantovani A ( 1986 ) . Mechanisms of natural cell-mediated resistance in human solid tumors . Biochimica et Biophysica Acta vol. 865 , ( 3 ) 281 - 288 .

Wang JM, Cianciolo GJ, Snyderman R, Mantovani A ( 1986 ) . Coexistence of a chemotactic factor and a retroviral P15E-related chemotaxis inhibitor in human tumor cell culture supernatants . The Journal of Immunology vol. 137 , ( 8 ) 2726 - 2732 .

Bersani L, Colotta F, Mantovani A ( 1986 ) . Involvement of tumour necrosis factor in monocyte-mediated rapid killing of actinomycin D-pretreated WEHI 164 sarcoma cells . Immunology vol. 59 , ( 2 ) 323 - 325 .

Allavena P, Zanaboni F, Rossini S, Merendino A, Bonazzi C, Vassena L, Mangioni C, Mantovani A ( 1986 ) . Lymphokine-Activated Killer Activity of Tumor-Associated and Peripheral Blood Lymphocytes Isolated From Patients With Ascites Ovarian Tumors2 . Journal of the National Cancer Institute vol. 77 , ( 4 ) 863 - 868 .

Bussolino F, Breviario F, Tetta C, Aglietta M, Sanavio F, Mantovani A, Dejana E ( 1986 ) . Interleukin 1 stimulates platelet activating factor production in cultured human endothelial cells . Pharmacological Research Communications vol. 18 , 133 - 137 .

Polentarutti N, Bottazzi B, Balotta C, Erroi A, Mantovani A ( 1986 ) . Modulation of the locomotory capacity of human large granular lymphocytes . Cellular Immunology vol. 101 , ( 1 ) 204 - 212 .

Mantovani A, Ming WJ, Balotta C, Abdeljalil B, Bottazzi B ( 1986 ) . Origin and regulation of tumor-associated macrophages: the role of tumor-derived chemotactic factor . Biochimica et Biophysica Acta vol. 865 , ( 1 ) 59 - 67 .

Lazzarin A, Uberti Foppa C, Galli M, Mantovani A, Poli G, Franzetti F, Nóvati R ( 1986 ) . Impairment of polymorphonuclear leucocyte function in patients with acquired immunodeficiency syndrome and with lymphadenopathy syndrome . Clinical & Experimental Immunology vol. 65 , ( 1 ) 105 - 111 .

Languino LR, Colella S, Polentarutti N, Maes L, Mantovani A, Marguerie G, Dejana E ( 1986 ) . Fibrinogen-endothelial cell interaction . Cell Biology International vol. 10 , ( 6 )

Bussolino F, Breviario F, Tetta C, Aglietta M, Mantovani A, Dejana E ( 1986 ) . Interleukin 1 stimulates platelet-activating factor production in cultured human endothelial cells . Journal of Clinical Investigation vol. 77 , ( 6 ) 2027 - 2033 .

Rambaldi A, Alessio G, Casali B, Passerini CG, Donati MB, Mantovani A, Semeraro N ( 1986 ) . Induction of monocyte-macrophage procoagulant activity by transformed cell lines . The Journal of Immunology vol. 136 , ( 10 ) 3848 - 3855 .

Colotta F, Polentarutti N, Bersani L, Poll G, Mantovani A ( 1986 ) . Rapid Killing of Actinomycin D-Treated Tumor Cells by Mononuclear Phagocytes: Characterization of Effector Cells in Mice . Journal of Leukocyte Biology vol. 39 , ( 2 ) 205 - 221 .

Collota F, Bersani L, Polentarutti N, Mantovani A ( 1986 ) . Rapid killing of actinomycin D-treated tumour cells by mononuclear phagocytes: reactivity in mouse strains with defective classical tumour cytotoxicity . Immunology vol. 57 , ( 2 ) 249 - 253 .

Bottazzi B, Mantovani A, Taraboletti G, Giavazzi R ( 1986 ) . Characterization of spontaneous metastases from autochthonous 3-methylcholanthrene-induced tumors . Invasion and Metastasis vol. 6 , ( 1 ) 44 - 57 .

Nencioni L, Villa L, Poli G, Mantovani A, Lazzarin A, Fanetti G, Masello LC, Tagliabue A ( 1986 ) . Deficient natural-cell mediated immunity against "Salmonella typhi" in patients with LAS and AIDS . Annali Sclavo. Collana Monografica vol. 3 , ( 1-2 ) 99 - 102 .

Peri G, Zanaboni F, Rossini S, Mangioni C, Landoni F, Epis A, Mantovani A ( 1986 ) . Evaluation of the interaction of mononuclear phagocytes with ovarian carcinoma cells in a colony assay . British Journal of Cancer vol. 53 , ( 1 ) 47 - 52 .

Rambaldi A, Allavena P, Pirelli A, Di Bello M, Rossini S, Bassan R, Barbui T, Pelicci PG et al. ( 1986 ) . Immunological and genotypic analysis of human Tγ-lymphoproliferative disorders . International Journal of Clinical & Laboratory Research vol. 16 , ( 1 ) 29 - 35 .

Bottazzi B, Rambaldi A, Introna M, Merendino A, Piovella F, Bassan R, Viero P, Barbui T et al. ( 1986 ) . Migratory capacity of large granular lymphocytes from T-gamma-lymphoproliferative disorders . Natural Immunity vol. 5 , ( 1 ) 19 - 27 .

Mantovani A, Biondi A ( 1986 ) . Novel Approaches in Immune Manipulation . Advances in Immunopharmacology , Elsevier

Pacchiarini L, Grignani G, Pagliarino M, Ricetti MM, Bottazzi B, Mantovani A, Ascari E ( 1986 ) . Role of tumor proteinases in tumor cell-induced platelet aggregation . Invasion and Metastasis vol. 6 , ( 5 ) 287 - 301 .

Polentarutti N, Acero R, Bottazzi B, Taraboletti G, Mantovani A ( 1986 ) . The Macrophage Content of Tumors Is Unrelated to Levels of NK Cell-Mediated Resistance . Journal of Leukocyte Biology vol. 39 , ( 1 ) 113 - 119 .

Rambaldi A, Pelicci PG, Allavena P, Knowles DM, Rossini S, Bassan R, Barbui T, Dalla-Favera R et al. ( 1985 ) . T cell receptor beta chain gene rearrangements in lymphoproliferative disorders of large granular lymphocytes/natural killer cells . Journal of Experimental Medicine vol. 162 , ( 6 ) 2156 - 2162 .

Poli G, Bottazzi B, Acero R, Bersani L, Rossi V, Introna M, Lazzarin A, Galli M et al. ( 1985 ) . Monocyte function in intravenous drug abusers with lymphadenopathy syndrome and in patients with acquired immunodeficiency syndrome: selective impairment of chemotaxis . Clinical & Experimental Immunology vol. 62 , ( 1 ) 136 - 142 .

Poli G, Introna M, Zanaboni F, Peri G, Carbonari M, Aiuti F, Lazzarin A, Moroni M et al. ( 1985 ) . Natural killer cells in intravenous drug abusers with lymphadenopathy syndrome . Clinical & Experimental Immunology vol. 62 , ( 1 ) 128 - 135 .

Rossi V, Breviario F, Ghezzi P, Dejana E, Mantovani A ( 1985 ) . Prostacyclin Synthesis Induced in Vascular Cells by Interleukin-1 . Science vol. 229 , ( 4709 ) 174 - 176 .

Colotta F, Bersani L, Lazzarin A, Poli G, Mantovani A ( 1985 ) . Rapid killing of actinomycin D-treated tumor cells by human monocytes. II. Cytotoxicity is independent of secretion of reactive oxygen intermediates and is suppressed by protease inhibitors . The Journal of Immunology vol. 134 , ( 5 ) 3524 - 3531 .

Mantovani A, Evans R ( 1985 ) . Tumor-infiltrating leukocytes . Trends in Immunology vol. 6 , ( 5 ) 144 - 145 .

Bottazzi B, Introna M, Allavena P, Villa A, Mantovani A ( 1985 ) . In vitro migration of human large granular lymphocytes . The Journal of Immunology vol. 134 , ( 4 ) 2316 - 2321 .

Lorenzet R, Bottazzi B, Locati D, Colucci M, Mantovani A, Semeraro N, Donati MB ( 1985 ) . Failure of warfarin to affect the tissue factor activity and the metastatic potential of murine fibrosarcoma cells . European Journal of Cancer vol. 21 , ( 2 ) 263 - 265 .

Colotta F, Bersani L, Polentarutti N, Peri G, Mantovani A ( 1985 ) . Effects of a streptococcal preparation (OK-432) on macrophage functions in mice . International Journal of Immunopharmacology . vol. 7 ,

Polentarutti N, Bottazzi B, Rossini S, Zanaboni F, Mantovani A ( 1985 ) . In vitro migration of human large granular lymphocytes: Modulation streptococcal preparation . International Journal of Immunopharmacology . vol. 7 ,

Dejana E, Languino LR, Polentarutti N, Balconi G, Ryckewaert JJ, Larrieu MJ, Donati MB, Mantovani A et al. ( 1985 ) . Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding . Journal of Clinical Investigation vol. 75 , ( 1 ) 11 - 18 .

Bersani L, Colotta F, Ghezzi P, Mantovani A ( 1985 ) . Rapid killing of actinomycin D-treated tumor cells-cytotoxicity of cell-free monocyte supernatants . Immunology Letters vol. 11 , ( 5-6 ) 351 - 355 .

Bersani L, Colotta F, Peri G, Villa A, Mantovani A ( 1985 ) . Regulation of tumor cell susceptibility to macrophage cytotoxicity . International Journal of Immunopharmacology . vol. 7 ,

Dejana E, Breviario F, Balconi G, Rossi V, Remuzzi G, de Gaetano G, Mantovani A ( 1984 ) . Stimulation of Prostacyclin Synthesis in Vascular Cells by Mononuclear Cell Products . Blood vol. 64 , ( 6 ) 1280 - 1283 .

Lazzarin A, Galli M, Negri C, Moroni M, Introna M, Mantovani A, Mella L, Trombini M et al. ( 1984 ) . Outbreak of persistent, unexplained, generalized lymphadenopathy with immunological abnormalities in drug addicts in Milan . Infection vol. 12 , ( 6 ) 372 - 376 .

Mantovani A ( 1984 ) . Tumor-associated macrophages and lymphoid cells in human tumors . Clinical and Applied Immunology Reviews vol. 5 , ( 10 ) 141 - 143 .

Villa A, Peri G, Rossi V, Delia D, Mantovani A ( 1984 ) . Monoclonal antibody-defined surface markers of effector cells involved in human monocyte cytotoxicity . Cellular Immunology vol. 87 , ( 2 ) 494 - 503 .

Vicenzi E, Biondi A, Bordignon C, Rambaldi A, Donati MB, Mantovani A ( 1984 ) . Human mononuclear phagocytes from different anatomical sites differ in their capacity to metabolize arachidonic acid . Clinical & Experimental Immunology vol. 57 , ( 2 ) 385 - 392 .

Guaitani A, Polentarutti N, Filippeschi S, Marmonti L, Corti F, Italia C, Coccioli G, Donelli MG et al. ( 1984 ) . Effects of disodium etidronate in murine tumor models . European Journal of Cancer vol. 20 , ( 5 ) 685 - 693 .

Ghezzi P, Bianchi M, Mantovani A, Spreafico F, Salmona M ( 1984 ) . Enhanced xanthine oxidase activity in mice treated with interferon and interferon inducers . Biochemical and Biophysical Research Communications vol. 119 , ( 1 ) 144 - 149 .

Colotta F, Peri G, Villa A, Mantovani A ( 1984 ) . Rapid killing of actinomycin D-treated tumor cells by human mononuclear cells. I. Effectors belong to the monocyte-macrophage lineage . The Journal of Immunology vol. 132 , ( 2 ) 936 - 944 .

Biondi A, Landolfo S, Fumaroa D, Polentarutti N, Introna M, Mantovani A ( 1984 ) . Evaluation of absorption with Limulus amebocyte lysate to remove contaminating endotoxin from interferon and lymphokine preparations . Journal of Immunological Methods vol. 66 , ( 1 ) 103 - 112 .

Forni G, Bindoni M, Santoni A, Giovarelli M, Mantovani A ( 1984 ) . Physiological and pathological influences of central nervous system on the immune system: A critical appraisal . Journal of Psychiatric Research vol. 18 , ( 4 ) 491 - 499 .

Semeraro N, Biondi A, Lorenzet R, Locati D, Mantovani A, Donati MB ( 1983 ) . Direct induction of tissue factor synthesis by endotoxin in human macrophages from diverse anatomical sites . Immunology vol. 50 , ( 4 ) 529 - 535 .

Introna M, Mantovani A ( 1983 ) . Natural killer cells in human solid tumors . Cancer and Metastasis Reviews vol. 2 , ( 4 ) 337 - 350 .

Colotta F, Rambaldi A, Colombo N, Tabacchi L, Introna M, Mantovani A ( 1983 ) . Effect of a streptococcal preparation (OK432) on natural killer activity of tumour-associated lymphoid cells in human ovarian carcinoma and on lysis of fresh ovarian tumour cells . British Journal of Cancer vol. 48 , ( 4 ) 515 - 525 .

Lorenzet R, Peri G, Locati D, Allavena P, Colucci M, Semeraro N, Mantovani A, Donati MB ( 1983 ) . Generation of Procoagulant Activity by Mononuclear Phagocytes: A Possible Mechanism Contributing to Blood Clotting Activation Within Malignant Tissues . Blood vol. 62 , ( 2 ) 271 - 273 .

Peri G, Polentarutti N, Filippeschi S, Malfiore C, Amato G, Pepe S, Bonati M, Garattini S et al. ( 1983 ) . In vitro and in vivo cytotoxicity of possible uracil metabolites of methylxanthines . Toxicology Letters vol. 18 , ( 1-2 ) 133 - 140 .

Bottazzi B, Polentarutti N, Acero R, Balsari A, Boraschi D, Ghezzi P, Salmona M, Mantovani A ( 1983 ) . Regulation of the Macrophage Content of Neoplasms by Chemoattractants . Science vol. 220 , ( 4593 ) 210 - 212 .

Biondi A, Peri G, Lorenzet R, Fumarola D, Mantovani A ( 1983 ) . Role of endotoxin in the expression of human monocyte cytotoxicity . Journal of Leukocyte Biology vol. 33 , ( 4 ) 315 - 327 .

Introna M, Allavena P, Biondi A, Colombo N, Villa A, Mantovani A ( 1983 ) . Defective Natural Killer Activity Within Human Ovarian Tumors: Low Numbers of Morphologically Defined Effectors Present in Situ23 . Journal of the National Cancer Institute vol. 70 , ( 1 ) 21 - 26 .

Mantovani A, Tagliabue A ( 1983 ) . Modulation of Mononuclear Phagocytes by Cancer Chemotherapeutic Agents . The Reticuloendothelial System , Springer Nature

BIONDI A, BORDIGNON C, PERI G, DONATI MB, VICENZI E, GHEZZI P, SALMONA M, MANTOVANI A ( 1983 ) . Regulation of the Tumoricidal and Suppressive Activity of Human Macrophages . Advances in Immunopharmacology , Elsevier

Marelli O, Mantovani A, Franco P, Nicotin A ( 1982 ) . Macrophage Antitumor Activity Induced by the Antigenic Lymphoma L5178Y/DTIC Subline . Tumori Journal vol. 68 , ( 5 ) 365 - 371 .

Biondi A, Peri G, Colombo N, Bolis G, Mantovani A ( 1982 ) . Antibody-dependent and -independent cytotoxicity of human mononuclear phagocytes: defective stimulation of tumoricidal activity in milk macrophages . Clinical & Experimental Immunology vol. 49 , ( 3 ) 701 - 708 .

Bordignon C, Villa F, Allavena P, Introna M, Biondi A, Avallone R, Mantovani A ( 1982 ) . Inhibition of natural killer activity by human bronchoalveolar macrophages . The Journal of Immunology vol. 129 , ( 2 ) 587 - 591 .

Allavena P, Introna M, Sessa C, Mangioni C, Mantovani A ( 1982 ) . Interferon Effect on Cytotoxicity of Peripheral Blood and Tumor-Associated Lymphocytes Against Human Ovarian Carcinoma Cells23 . Journal of the National Cancer Institute vol. 68 , ( 4 ) 555 - 562 .

Herberman RB, Ortaldo JR, Mantovani A, Hobbs DS, Kung H-F, Pestka S ( 1982 ) . Effect of human recombinant interferon on cytotoxic activity of natural killer (NK) cells and monocytes . Cellular Immunology vol. 67 , ( 1 ) 160 - 167 .

Garattini S, Erba E, Morasca L, Peri G, Mantovani A, Filippeschi S, Spreafico F, Arnaud M ( 1982 ) . In vitro and in vivo cytotoxicity of 6 amino-5-formylmethylamino-1,3-dimethyl uracil, a uracilic metabolite of caffeine . Toxicology Letters vol. 10 , ( 2-3 ) 313 - 319 .

Bordignon C, Villa F, Vecchi A, Giavazzi R, Introna M, Avallone R, Mantovani A ( 1982 ) . Natural cytotoxic activity in human lungs . Clinical & Experimental Immunology vol. 47 , ( 2 ) 437 - 444 .

Donati MB, Rotillio D, Delaini F, Giavazzi R, Mantovani A, Poggi A ( 1982 ) . Animal models for the study of platelet-tumor cell interactions . Progress in Clinical and Biological Research vol. 89 , 159 - 176 .

Mantovani A, Bordignon C, Biondi A, Introna M, Allavena P ( 1982 ) . Cytotoxicity on Tumor Cells of Human Macrophages: Functional Status of Tumor-Associated Effector Cells . Advances in Experimental Medicine and Biology vol. 141 , 99 - 108 .

Introna M, Sessa C, Peri G, Allavena P, Polentarutti N, Mangioni C, Mantovani A ( 1982 ) . Effect of i.p. C. Parvum on the tumoricidal activity of tumor-associated macrophages and tumor-associated lymphocytes from ascitic ovarian tumors . International Journal of Immunopharmacology vol. 4 , ( 4 )

Boraschi D, Mantovani A ( 1982 ) . Genetic Aspects of Macrophage Activation for Tumor Cytotoxicity . Biochemistry and Function of Phagocytes , vol. 141 , Springer Nature

Garattini S, Vecchi A, Sironi M, Mantovani A ( 1982 ) . IMMUNOSUPPRESSANT ACTIVITY OF TCDD IN MICE . Chlorinated Dioxins & Related Compounds , Elsevier

Bordignon C, Allavena P, Introna M, Biondi A, Bottazzi B, Mantovani A ( 1982 ) . MODULATION OF NK ACTIVITY BY HUMAN MONONUCLEAR PHAGOCYTES: SUPPRESSIVE ACTIVITY OF BRONCHO-ALVEOLAR MACROPHAGES1 . NK Cells and Other Natural Effector Cells , Elsevier

Ruco LP, Meltzer MS, Leonard EJ, Tomisawa S, Mantovani A ( 1982 ) . Macrophage Activation for Tumor Cytotoxicity: Reactivity of Peritoneal and Bone Marrow Macrophages . Biochemistry and Function of Phagocytes , vol. 141 , Springer Nature

Spreafico F, Mantovani A, Giavazzi R, Conti G, Anaclerio A ( 1982 ) . Metastatic Potential of Metastases, Tumor Cell Heterogeneity, and Therapeutic Implications . Recent Results in Cancer Research vol. 80 , 1 - 8 .

Biondi A, Bottazzi B, Peri G, Polentarutti N, Caspani G, Mantovani A ( 1982 ) . NATURAL CYTOTOXICITY OF HUMAN MONONUCLEAR PHAGOCYTES: ROLE OF CONTAMINATING ENDOTOXIN AND EXPRESSION BY DIFFERENT MACROPHAGE POPULATIONS1 . NK Cells and Other Natural Effector Cells , Elsevier

Introna M, Allavena P, Acero R, Colombo N, Molina P, Mantovani A ( 1982 ) . NATURAL KILLER ACTIVITY IN HUMAN OVARIAN TUMORS1 . NK Cells and Other Natural Effector Cells , Elsevier

Mantovani A ( 1982 ) . The Interaction of Cancer Chemotherapy Agents with Mononuclear Phagocytes . Advances in Pharmacology vol. 19 , 35 - 65 .

Peri G, Biondi A, Bottazzi B, Polentarutti N, Bordignon C, Mantovani A ( 1982 ) . Tumoricidal and Immunoregulatory Activity of Macrophages from Human Ovarian Carcinomas . Advances in Experimental Medicine and Biology vol. 155 , 737 - 744 .

Mantovani A, Polentarutti N, Peri G, Martinotti G, Landolfo S ( 1981 ) . Cytotoxicity of human peripheral blood monocytes against Trichomonas vaginalis . Clinical & Experimental Immunology vol. 46 , ( 2 ) 391 - 396 .

Allavena P, Introna M, Mangioni C, Mantovani A ( 1981 ) . Inhibition of Natural Killer Activity by Tumor-Associated Lymphoid Cells From Ascites Ovarian Carcinomas23 . Journal of the National Cancer Institute vol. 67 , ( 2 ) 319 - 325 .

Alessandri G, Giavazzi R, Falautano P, Spreafico F, Garattini S, Mantovani A ( 1981 ) . A murine ovarian tumor with unique metastasizing capacity . European Journal of Cancer vol. 17 , ( 6 ) 651 - 653 .

Luini W, Mantovani A, Garattini S ( 1981 ) . Effects of saccharin on primary humoral antibody production in rats . Toxicology Letters vol. 8 , ( 1-2 ) 1 - 6 .

Colucci M, Giavazzi R, Alessandri G, Semeraro N, Mantovani A, Donati MB ( 1981 ) . Procoagulant Activity of Sarcoma Sublines With Different Metastatic Potential . Blood vol. 57 , ( 4 ) 733 - 735 .

Zanella A, Mantovani A, Mariani M, Silvani C, Peri G, Tedesco F ( 1981 ) . A modified ‘low pH’ lignocaine method to isolate human monocytes: A comparison with other separation procedures . Journal of Immunological Methods vol. 41 , ( 3 ) 279 - 288 .

INTRONA M, ALLAVENA P, SPREAFICO F, MANTOVANI A ( 1981 ) . INHIBITION OF HUMAN NATURAL KILLER ACTIVITY BY CYCLOSPORIN A . Transplantation vol. 31 , ( 2 ) 113 - 116 .

Mantovani A, Giavazzi R, Alessandri G, Spreafico F, Garattini S ( 1981 ) . Characterization of tumor lines derived from spontaneous metastases of a transplanted murine sarcoma . European Journal of Cancer vol. 17 , ( 1 ) 71 - 76 .

Spreafico F, Mantovani A ( 1981 ) . Immunomodulation by cancer chemotherapeutic agents and antineoplastic activity . Pathobiology Annual vol. 11 , 177 - 195 .

SPREAFICO F, VECCHI A, MANTOVANI A, TAGLIABUE A, SIRONI M, LUINI W, GARATTINI S ( 1981 ) . The Assessment of the Immunotoxicity of Xenobiotics Experience with Tetrachlorodibenzodioxin and Saccharin . Advances in Immunopharmacology , Elsevier

Delaini F, Giavazzi R, De Bellis Vitti G, Alessandri G, Mantovani A, Donati MB ( 1981 ) . Tumour sublines with different metastatic capacity induce similar blood coagulation changes in the host . British Journal of Cancer vol. 43 , ( 1 ) 100 - 104 .

Mantovani A, Vecchi A, Luini W, Sironi M, Candiani GP, Spreafico F, Garattini S ( 1980 ) . Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on macrophage and natural killer cell-mediated cytotoxicity in mice . Biomedicine & Pharmacotherapy vol. 32 , ( 4 ) 200 - 204 .

Jett JR, Mantovani A, Herberman RB ( 1980 ) . Augmentation of human monocyte-mediated cytolysis by interferon . Cellular Immunology vol. 54 , ( 2 ) 425 - 434 .

Giavazzi R, Alessandri G, Spreafico F, Garattini S, Mantovani A ( 1980 ) . Metastasizing capacity of tumour cells from spontaneous metastases of transplanted murine tumours . British Journal of Cancer vol. 42 , ( 3 ) 462 - 472 .

Bordignon C, Avallone R, Peri G, Polentarutti N, Mangioni C, Mantovani A ( 1980 ) . Cytotoxicity on tumour cells of human mononuclear phagocytes: defective tumoricidal capacity of alveolar macrophages . Clinical & Experimental Immunology vol. 41 , ( 2 ) 336 - 342 .

Mantovani A, Polentarutti N, Peri G, Shavit ZB, Vecchi A, Bolis G, Mangioni C ( 1980 ) . Cytotoxicity on Tumor Cells of Peripheral Blood Monocytes and Tumor-Associated Macrophages in Patients With Ascites Ovarian Tumors23 . Journal of the National Cancer Institute vol. 64 , ( 6 ) 1307 - 1315 .

Vecchi A, Mantovani A, Sironi M, Luini W, Cairo M, Garattini S ( 1980 ) . Effect of acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on humoral antibody production in mice . Chemico-Biological Interactions vol. 30 , ( 3 ) 337 - 342 .

Mantovani A, Luini W, Candiani GP, Salmona M, Spreafico F, Garattini S ( 1980 ) . In vitro effects of saccharin on cell-mediated host defence mechanisms . Toxicology Letters vol. 5 , ( 3-4 ) 287 - 295 .

Mantovani A, Bar Shavit Z, Peri G, Polentarutti N, Bordignon C, Sessa C, Mangioni C ( 1980 ) . Natural cytotoxicity on tumour cells of human macrophages obtained from diverse anatomical sites . Clinical & Experimental Immunology vol. 39 , ( 3 ) 776 - 784 .

Mantovani A, Luini W, Candiani GP, Spreafico F ( 1980 ) . Effect of chemotherapeutic agents on natural and BCG-stimulated macrophage cytotoxicity in mice . International Journal of Immunopharmacology vol. 2 , ( 4 ) 333 - 339 .

Mantovani A, Filippini I, Bergomi S ( 1980 ) . Findings on an epidemic of human trichinelliasis verified in Italy . Parassitologia vol. 22 , ( 1-2 ) 107 - 134 .

Vecchi A, Sironi M, Mantovani A, Spreafico F, Garattini S ( 1980 ) . Immunotoxicological effects of TCDD in different mouse strains . International Journal of Immunopharmacology . vol. 2 , 235 - 236 .

Introna M, Allavena P, Spreafico F, Mantovani A ( 1980 ) . Impairement of human NK activity by cyclosporin A . International Journal of Immunopharmacology . vol. 2 ,

Mantovani A, Giavazzi R, Alessandri G, Spreafico F, Garattini S ( 1980 ) . Metastatic Potential of Tumor Cells from Spontaneous Metastasis . Metastasis , Springer Nature

Mantovani A, Peri G, Polentarutti N, Allavena P, Bordignon C, Sessa C, Mangioni C ( 1980 ) . NATURAL CYTOTOXICITY ON TUMOR CELLS OF HUMAN MONOCYTES AND MACROPHAGES11This work was supported by C.N.R. (No. 79.00643.96, No. 79.02417.65 and No. 78.02166.04), by the Rotolo Fund and by Grant IROI CA 26824 from National Cancer Institute . Natural Cell-mediated Immunity Against Tumors , Elsevier

Vecchi A, Sironi M, Serraglia N, Mantovani A, Spreafico F ( 1980 ) . On the immunomodulatory activity on NPT 15392: In vitro effects on mouse and human cells . International Journal of Immunopharmacology . vol. 2 , 204 - 205 .

Vecchi A, Mantovani A, Sironi M, Luini W, Spreafico F, Garattini S ( 1980 ) . The Effect of Acute Administration of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) on Humoral Antibody Production and Cell-Mediated Activities in Mice . Archives of Toxicology vol. 4 , 163 - 165 .

Mantovani A, Polentarutti N, Luini W, Peri G, Spreafico F ( 1979 ) . Role of Host Defense Mechanisms in the Antitumor Activity of Adriamycin and Daunomycin in Mice2 . Journal of the National Cancer Institute vol. 63 , ( 1 ) 61 - 66 .

Tagliabue A, Mantovani A, Kilgallen M, Herberman RB, McCoy JL ( 1979 ) . Natural cytotoxicity of mouse monocytes and macrophages . The Journal of Immunology vol. 122 , ( 6 ) 2363 - 2370 .

Mantovani A, Polentarutti N, Gritti P, Bolis G, Maggioni A, Spreafico F ( 1979 ) . K cell activity in ovarian cancer patients given chemotherapy . European Journal of Cancer vol. 15 , ( 5 ) 797 - 802 .

Mantovani A, Luini W, Peri G, Vecchi A, Spreafico F ( 1978 ) . Effect of Chemotherapeutic Agents on Natural Cell-Mediated Cytotoxicity in Mice2 . Journal of the National Cancer Institute vol. 61 , ( 5 ) 1255 - 1261 .

Tagliabue A, Allesandri G, Polentarutti N, Mantovani A, Falantano E, Vecchi A, Garattini S, Spreafico F ( 1978 ) . The immunostimulatory activity of 3-(p-chlorophenyl)-2,3-dihydro-3-hydroxythiazole [3, 2-α]-benzimidazole-2-acetic acid (NSC 208828) . European Journal of Cancer vol. 14 , ( 4 ) 393 - 400 .

Mantovani A, Polentarutti N, Sironi M, Vecchi A, Spreafico F, Garattini S ( 1978 ) . Macrophage-mediated cytostatic activity on tumour cells after treatment with Triton WR 1339 . European Journal of Cancer vol. 14 , ( 3 ) 229 - 235 .

Vecchi A, Cairo M, Mantovani A, Sironi M, Spreafico F ( 1978 ) . Comparative antineoplastic activity of adriamycin and N-trifluoroacetyladriamycin-14-valerate . Journal of the National Cancer Institute vol. 62 , ( 1 ) 111 - 117 .

Facchinetti T, Mantovani A, Cantoni L, Cantoni R, Salmona M ( 1978 ) . Intercalation with DNA is a prerequisite for Daunomycin, Adriamycin and its congeners in inhibiting DNAase I . Chemico-Biological Interactions vol. 20 , ( 1 ) 97 - 102 .

Mantovani A, Polentarutti N, Alessandri G, Vecchi A, Giuliani F, Spreafico F ( 1977 ) . Activation of K cells in mice with transplanted tumours differing in immunogenicity and metastasizing capacity . British Journal of Cancer vol. 36 , ( 4 ) 453 - 460 .

Facchinetti T, Mantovani A, Cantoni R, Cantoni L, Pantarotto C, Salmona M ( 1977 ) . Effect of daunomycin, adriamycin and its congener AD 32 on the activity of DNase I from bovine pancreas . Biochemical Pharmacology vol. 26 , ( 20 ) 1953 - 1954 .

Tagliabue A, Mantovani A, Polentarutti N, Vecchi A, Spreafico F ( 1977 ) . Effect of Immunomodulators on Effector Cells Involved in Antibody-Dependent Cellular Cytotoxicity: Brief Communication2 . Journal of the National Cancer Institute vol. 59 , ( 3 ) 1019 - 1022 .

Tagliabue A, Polentarutti N, Vecchi A, Mantovani A, Spreafico F ( 1977 ) . Combination chemo-immunotherapy with adriamycin in experimental tumor systems . European Journal of Cancer vol. 13 , ( 7 ) 657 - 665 .

Mantovani A, Vecchi A, Tagliabue A, Spreafico F ( 1977 ) . 159 THE DIFFERENTIAL IMMUNOSUPPRESSIVE ACTIVITY OF ADRIAMYCIN (AM) AND DAUNOMYCIN (DM) :RELEVANCE TO THE ANTINEOPLASTIC ACTIVITY(°)(°)Supported by Contract N°. NIH NCI C 72-3242 . Abstracts , Elsevier

Vecchi A, Fioretti MC, Mantovani A, Barzi A, Spreafico F ( 1976 ) . THE IMMUNODEPRESSIVE AND HEMATOTOXIC ACTIVITY OF IMIDAZOLE-4-CARBOXAMIDE,5-(3,3-DIMETHYL-1-TRIAZENO) IN MICE . Transplantation vol. 22 , ( 6 ) 619 - 624 .

Mantovani A, Tagliabue A, Vecchi A, Spreafico F ( 1976 ) . Effects of adriamycin and daunomycin on spleen cell populations in normal and tumor allografted mice . European Journal of Cancer vol. 12 , ( 5 ) 381 - 387 .

Mantovani A, Vecchi A, Tagliabue A, Spreafico F ( 1976 ) . The effects of adriamycin and daunomycin on antitumoral immune effector mechanisms in an allogeneic system . European Journal of Cancer vol. 12 , ( 5 ) 371 - 379 .

Vecchi A, Mantovani A, Tagliabue A, Spreafico F ( 1976 ) . A characterization of the immunosuppressive activity of adriamycin and daunomycin on humoral antibody production and tumor allograft rejection . Cancer Research vol. 36 , ( 4 ) 1222 - 1227 .

Mantovani A, Tagliabue A, Vecchi A, Spreafico F ( 1976 ) . Effect of Corynebacterium parvum on cellular and humoral antitumoral immune effector mechanisms . European Journal of Cancer vol. 12 , ( 2 ) 113 - 123 .

Vecchi A, Tagliabue A, Mantovani A, Anaclerio A, Barale C, Spreafico F ( 1976 ) . Steroid contraceptive agents and immunological reactivity in experimental animals . Biomedicine & Pharmacotherapy vol. 24 , ( 4 ) 231 - 237 .

Mantovani A, Spreafico F ( 1975 ) . Allogeneic tumor enhancement by levamisole, a new immunostimulatory compound: Studies on cell-mediated immunity and humoral antibody response . European Journal of Cancer vol. 11 , ( 8 ) 537 - 544 .

Mantovani A, Veechi A, Spreafico F ( 1975 ) . Brief Communication: The Attacker: Target-Cell Ratio and Serum Effects on In Vitro Cell-Mediated Immunity . Journal of the National Cancer Institute vol. 55 , ( 2 ) 483 - 484 .

Spreafico F, Vecchi A, Mantovani A, Poggi A, Franchi G, Anaclerio A, Garattini S ( 1975 ) . Characterization of the immunostimulants levamisole and tetramisole . European Journal of Cancer vol. 11 , ( 8 ) 555 - 563 .

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