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  1. Queen Mary University of London
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Publications: DR Fiona Lewis

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Kobayashi K, Ichihara Y, Tano N, Fields L, Murugesu N, Ito T, Ikebe C, Lewis F et al. ( 2025 ) . Author Correction: Fibrin Glue-aided, Instant Epicardial Placement Enhances the Efficacy of Mesenchymal Stromal Cell-Based Therapy for Heart Failure . Scientific Reports vol. 15 , ( 1 ) Article 20300 ,
Yesilyurt-Dirican ZE, Qi C, Wang Y-C, Simm A, Deelen L, Hafiz Abbas Gasim A, Lewis-McDougall F, Ellison-Hughes GM ( 2025 ) . SGLT2 inhibitors as a novel senotherapeutic approach . npj Aging vol. 11 , ( 1 ) Article 35 ,
Ruchaya PJ, Lewis-McDougall FC, Sornkarn N, Amin S, Grimsdell B, Shaalan A, Gritti G, Soe KT et al. ( 2024 ) . Correction: Ruchaya et al. Transplantation of Skeletal Muscle-Derived Sca-1+/PW1+/Pax7− Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction. Cells 2022, 11, 4050 . Cells vol. 13 , ( 11 ) 895 - 895 .
Fields L, Ito T, Kobayashi K, Ichihara Y, Podaru M-N, Hussain M, Yamashita K, Machado V et al. ( 2024 ) . Epicardial placement of human MSC-loaded fibrin sealant films for heart failure: Preclinical efficacy and mechanistic data . Molecular Therapy vol. 32 , ( 2 ) 562 - 562 .
Ruchaya PJ, Lewis-McDougall FC, Sornkarn N, Amin S, Grimsdell B, Shaalan A, Gritti G, Soe KT et al. ( 2022 ) . Transplantation of Skeletal Muscle-Derived Sca-1+/PW1+/Pax7− Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction . Cells vol. 11 , ( 24 ) 4050 - 4050 .
Smith AJ, Ruchaya P, Walmsley R, Wright KE, Lewis-McDougall FC, Bond J, Ellison-Hughes GM ( 2022 ) . Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells . Scientific Reports vol. 12 , ( 1 ) Article 10132 ,
Fields L, Ito T, Kobayashi K, Ichihara Y, Podaru M-N, Hussain M, Yamashita K, Machado V et al. ( 2021 ) . Epicardial placement of human MSC-loaded fibrin sealant films for heart failure: Preclinical efficacy and mechanistic data . Molecular Therapy vol. 29 , ( 8 ) 2554 - 2570 .
Ito T, Shintani Y, Fields L, Shiraishi M, Podaru M, Kainuma S, Yamashita K, Kobayashi K et al. ( 2021 ) . Cell barrier function of resident peritoneal macrophages in post-operative adhesions . Nature Communications vol. 12 , ( 1 ) Article 2232 ,
Podaru MN, Fields L, Kainuma S, Ichihara Y, Hussain M, Lewis F, Ito T, Kazuya K et al. ( 2019 ) . 2419Reparative macrophage transplantation for myocardial repair: a refinement of bone marrow mononuclear cell-based therapy . European Heart Journal . vol. 40 ,
Podaru M-N, Fields L, Kainuma S, Ichihara Y, Hussain M, Ito T, Kazuya K, D'Aquisto F et al. ( 2019 ) . Abstract 718: Reparative Macrophage Transplantation for Myocardial Repair: A Refinement of Bone Marrow Mononuclear Cell-Based Therapy . Circulation Research . vol. 125 ,
Podaru M-N, Fields L, Kainuma S, Ichihara Y, Hussain M, Ito T, Kobayashi K, Mathur A et al. ( 2019 ) . Reparative macrophage transplantation for myocardial repair: a refinement of bone marrow mononuclear cell-based therapy . Basic Research in Cardiology vol. 114 , ( 5 ) Article 34 ,
Kobayashi K, Ichihara Y, Sato N, Umeda N, Fields L, Fukumitsu M, Tago Y, Ito T et al. ( 2019 ) . On-site fabrication of Bi-layered adhesive mesenchymal stromal cell-dressings for the treatment of heart failure . Biomaterials vol. 209 , 41 - 53 .
Lewis‐McDougall FC, Ruchaya PJ, Domenjo‐Vila E, Shin Teoh T, Prata L, Cottle BJ, Clark JE, Punjabi PP et al. ( 2019 ) . Aged‐senescent cells contribute to impaired heart regeneration . Aging Cell vol. 18 , ( 3 ) Article e12931 ,
Podaru M-N, Fields L, Kainuma S, Ichihara Y, Hussain M, Ito T, Kazuya K, D'Aquisto F et al. ( 2019 ) . Reparative Macrophage Transplantation for Myocardial Repair: A Refinement of Bone Marrow Mononuclear Cell-Based Therapy . CIRCULATION RESEARCH . vol. 125 ,
Podaru MN, Fields L, Kainuma S, Ichihara Y, Hussain M, Lewis F, Ito T, Kazuya K et al. ( 2019 ) . Reparative macrophage transplantation for myocardial repair: a refinement of bone marrow mononuclear cell-based therapy . EUROPEAN HEART JOURNAL . vol. 40 , 1386 - 1386 .
Kobayashi K, Ichihara Y, Tano N, Fields L, Murugesu N, Ito T, Ikebe C, Lewis F et al. ( 2018 ) . Fibrin Glue-aided, Instant Epicardial Placement Enhances the Efficacy of Mesenchymal Stromal Cell-Based Therapy for Heart Failure . Scientific Reports vol. 8 , ( 1 ) Article 9448 ,
Lewis FC, Kumar SD, Ellison-Hughes GM ( 2018 ) . Non-invasive strategies for stimulating endogenous repair and regenerative mechanisms in the damaged heart . Pharmacological Research vol. 127 , 33 - 40 .
Kobayashi K, Ichihara Y, Sato N, Umeda N, Fields L, Fukumitsu M, Ito T, Podaru M et al. ( 2018 ) . On-Site, Instant Production of Bi-Layered Bio-Dressing Incorporating Mesenchymal Stromal Cells for the Treatment of Heart Failure . CIRCULATION . vol. 138 ,
Lewis FC, Cottle BJ, Shone V, Marazzi G, Sassoon D, Tseng CCS, Dankers PYW, Chamuleau SAJ et al. ( 2017 ) . Transplantation of Allogeneic PW1pos/Pax7neg Interstitial Cells Enhance Endogenous Repair of Injured Porcine Skeletal Muscle . JACC: Basic to Translational Science vol. 2 , ( 6 ) 717 - 736 .
Ellison-Hughes GM, Lewis FC ( 2017 ) . Progenitor Cells from the Adult Heart . Cardiac and Vascular Biology , Springer International Publishing
Agley CC, Lewis FC, Jaka O, Lazarus NR, Velloso C, Francis-West P, Ellison-Hughes GM, Harridge SDR ( 2017 ) . Active GSK3β and an intact β-catenin TCF complex are essential for the differentiation of human myogenic progenitor cells . Scientific Reports vol. 7 , ( 1 ) Article 13189 ,
Sarvananthan S, Punjabi PP, Lewis F, Latif N, Sarathchandra P, Yacoub M, Harding SE, Ellison-Hughes GM ( 2017 ) . P2551The distribution and characteristics of endogenous cardiac stem cells in the atria and ventricle of the adult human heart . European Heart Journal vol. 38 , ( suppl_1 )
Vicinanza C, Aquila I, Scalise M, Cristiano F, Marino F, Cianflone E, Mancuso T, Marotta P et al. ( 2017 ) . Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification . Cell Death & Differentiation vol. 24 , ( 12 ) 2101 - 2116 .
Cottle BJ, Lewis FC, Shone V, Ellison-Hughes GM ( 2017 ) . Skeletal muscle-derived interstitial progenitor cells (PICs) display stem cell properties, being clonogenic, self-renewing, and multi-potent in vitro and in vivo . Stem Cell Research & Therapy vol. 8 , ( 1 ) Article 158 ,
Attias J, Bieles J, Carvil P, Laing C, Lewis F, Jaka O, O'Brien K, Ruchaya P ( 2017 ) . Altitude exposure and increased heart rate: the role of the parasympathetic nervous system . The Journal of Physiology vol. 595 , ( 14 ) 4589 - 4590 .
Smith A, Wright K, Lewis F, Ellison G ( 2016 ) . P44 Tyrosine kinase inhibitor cardiotoxicity and cardiac stem cells . Heart vol. 102 , ( Suppl 8 )
Lewis FC, Teoh T, Domenjo-Vila E, Theologou T, Field M, Awad W, Yasin M, Nadal-Ginard B et al. ( 2016 ) . Canonical wnt signaling reverses the 'aged/senescent' human endogenous cardiac stem cell phenotype . CARDIOVASCULAR RESEARCH . vol. 111 , S92 - S92 .
Smith AJ, Lewis FC, Aquila I, Waring CD, Nocera A, Agosti V, Nadal-Ginard B, Torella D et al. ( 2014 ) . Isolation and characterization of resident endogenous c-Kit+ cardiac stem cells from the adult mouse and rat heart . Nature Protocols vol. 9 , ( 7 ) 1662 - 1681 .
Lewis FC, Henning BJ, Marazzi G, Sassoon D, Ellison GM, Nadal-Ginard B ( 2014 ) . Porcine Skeletal Muscle-Derived Multipotent PW1pos/Pax7neg Interstitial Cells: Isolation, Characterization, and Long-Term Culture . Stem Cells Translational Medicine vol. 3 , ( 6 ) 702 - 712 .
Torella D, Ellison GM, Torella M, Vicinanza C, Aquila I, Iaconetti C, Scalise M, Marino F et al. ( 2014 ) . Carbonic Anhydrase Activation Is Associated With Worsened Pathological Remodeling in Human Ischemic Diabetic Cardiomyopathy . Journal of the American Heart Association vol. 3 , ( 2 ) Article e000434 ,
Ellison GM, Smith AJ, Waring CD, Henning BJ, Burdina AO, Polydorou J, Vicinanza C, Lewis FC et al. ( 2013 ) . Adult Cardiac Stem Cells: Identity, Location and Potential . Stem Cell Biology and Regenerative Medicine , Springer New York
Bryan N, Lewis FC, Bond D, Stanley C, Hunt JA ( 2013 ) . Evaluation of a Novel Non-Destructive Catch and Release Technology for Harvesting Autologous Adult Stem Cells . PLoS ONE vol. 8 , ( 1 ) e53933 - e53933 .
Lewis F, Henning B, Sassoon D, Marazzi G, Ellison G, Nadal-Ginard B ( 2013 ) . Identification and characterisation of multipotent porcine PW1<SUP>+</SUP>/Pax7<SUP>-</SUP> skeletal muscle-derived interstitial cells (PICs) . HUMAN GENE THERAPY . vol. 24 , A30 - A30 .
Lewis FC, Bryan N, Hunt JA ( 2012 ) . A feeder-free, human plasma-derived hydrogel for maintenance of a human embryonic stem cell phenotype in vitro . Cell Regeneration vol. 1 , ( 1 ) Article 1:6 , 1:6 - 1:6 .
Lewis FC, Rhodes NP, Hunt JA ( 2011 ) . A novel, feeder free, autologous system for maintenance of human embryonic stem cell phenotype . European Cells and Materials . vol. 22 ,
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