Publications: DR Julia Ramirez Garcia

Sanghvi MM, Young WJ, Naderi H, Burns R, Ramírez J, Bell CG, Munroe PB ( 2025 ) . Using Genomics to Develop Personalized Cardiovascular Treatments . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 45 , ( 6 ) 866 - 881 .

Naderi H, Ramírez J, Van Duijvenboden S, Ruiz Pujadas E, Aung N, Wang L, Chamling B, Dörr M et al. ( 2025 ) . Diagnostic and prognostic value of ECG-predicted hypertension-mediated left ventricular hypertrophy using machine learning . Journal of Hypertension vol. 43 , ( 8 ) 1327 - 1338 .

Shah RA, Ramírez J, Kirkby C, Ives C, Lowe M, Munroe PB, Lambiase PD, Young WJ ( 2025 ) . Phenotypic expression of rare progressive cardiac conduction disease variants in the general population . Europace vol. 27 , ( 6 ) Article euaf103 ,

( 2025 ) . CARDIAC MAGNETIC RESONANCE CHARACTERISTICS AND PROGNOSTIC ASSOCIATIONS OF HYPERTENSION-MEDIATED LEFT VENTRICULAR HYPERTROPHY . Journal of Hypertension . vol. 43 , e33 - e33 .

Orera J, Ramírez J, García-Navarro P, Murillo J ( 2025 ) . RoePINNs: An integration of advanced CFD solvers with Physics-Informed Neural Networks and application in arterial flow modeling . Computer Methods in Applied Mechanics and Engineering vol. 440 , Article 117933 , 117933 - 117933 .

Svennberg E, Han JK, Caiani EG, Engelhardt S, Ernst S, Friedman P, Garcia R, Ghanbari H et al. ( 2025 ) . State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group on E-Cardiology . Europace vol. 27 , ( 5 ) Article euaf071 ,

Madrid J, Young WJ, van Duijvenboden S, Orini M, Munroe PB, Ramírez J, Mincholé A ( 2025 ) . Unsupervised clustering of single-lead electrocardiograms associates with prevalent and incident heart failure in coronary artery disease . European Heart Journal - Digital Health vol. 6 , ( 3 ) 435 - 446 .

Burns R, Dal Toso L, Mauger CA, Sojoudi A, Suinesiaputra A, Petersen SE, Ramírez J, Munroe PB et al. ( 2025 ) . Relationships between heart shape, function, and disease in 38,858 UK biobank participants . Journal of Cardiovascular Magnetic Resonance vol. 27 , ( 2 ) Article 101919 , 101919 - 101919 .

van Duijvenboden S, Nelson CP, Raisi-Estabragh Z, Ramirez J, Orini M, Wang Q, Aung N, Codd V et al. ( 2024 ) . Leucocyte telomere length and conduction system ageing . Heart vol. 111 , ( 7 ) 314 - 320 .

Orera J, Garcia-Navarro P, Ramírez J, Murillo J . Combined Estimation of Cross-sectional Area, Flow Rate and Pulse Wave Velocity Using Physics-Informed Neural Networks with 1D Hemodynamic Model Data . Computing in Cardiology Conference (CinC) . Conference: 2024 Computing in Cardiology Conference vol. 51 ,

Gómez Fonseca N, Ramírez J, S. Tsvetkova A, Platonov P, Azarov J, Pablo Martínez J, Laguna P . Dynamics of T-peak-to-T-end Morphology Changes in an Open-chest Porcine Model, and Its Relation to Arrhythmic Events . Computing in Cardiology Conference (CinC) . Conference: 2024 Computing in Cardiology Conference vol. 51 ,

Nicole Madrid J, Young W, van Duijvenboden S, Munroe P, Mincholé A, Ramírez J . ECG Based Unsupervised Clustering Model Predicts Heart Failure and Cardiovascular Diseases in Individuals without Cardiovascular Disease . Computing in Cardiology Conference (CinC) . Conference: 2024 Computing in Cardiology Conference vol. 51 ,

Artal S, Pablo Martínez J, Miguel A, Ramírez J . Improved Detection of Paroxysmal Atrial Fibrillation Using an ECG-based Semisupervised Model . Computing in Cardiology Conference (CinC) . Conference: 2024 Computing in Cardiology Conference vol. 51 ,

Ramírez J, van Duijvenboden S, Orini M, Lambiase PD, Tinker A, Young WJ, Munroe PB ( 2024 ) . Prediction of atrial and ventricular arrhythmias using multiple cardiovascular risk-factor polygenic risk scores . Heart Rhythm

Burns R, Young WJ, Aung N, Lopes LR, Elliott PM, Syrris P, Barriales-Villa R, Sohrabi C et al. ( 2024 ) . Genetic basis of right and left ventricular heart shape . Nature Communications vol. 15 , ( 1 ) Article 9437 ,

van Duijvenboden S, Ramírez J, Scheurink J, Darweesh SKL, Orini M, Tinker A, Munroe PB, Thannhauser J et al. ( 2024 ) . Cardiac autonomic function during exercise and incident Parkinson’s disease .

Young W, Sanghvi MM, Ramirez J, Orini M, Tinker A, Warren HR, Lambiase PD, Munroe PB ( 2024 ) . Circulating metabolites associate with the QT interval in individuals without prevalent cardiovascular disease . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.2742 ,

Naderi H, Ramirez J, Van Duijvenboden S, Ruiz Pujadas E, Aung N, Wang L, Chamling B, Dorr M et al. ( 2024 ) . Diagnostic and prognostic value of ECG-predicted hypertension mediated left ventricular hypertrophy using machine learning . European Heart Journal . vol. 45 ,

Ramirez J, Martinez JP, Van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Orini M, Munroe PB et al. ( 2024 ) . Long-term time-to-ventricular arrhythmic event prediction using a deep learning based model on the electrocardiogram signal . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.3434 ,

Van Duijvenboden S, Nicholson G, Smith-Byrne K, Portas L, Atkins J, Ramirez J, Orini M, Young WJ et al. ( 2024 ) . The genetic architecture of exercise-induced ventricular ectopy . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.3668 ,

Gómez N, Ramírez J, Martínez JP, Laguna P ( 2024 ) . Evaluation of T-wave Time-Warping Dynamics in Patients with Long QT Syndrome . 2024 13th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) . Conference: 2024 13th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) from: 23/10/2024 to: 25/10/2024 , 1 - 2 .

Gómez N, Ramírez J, Martín-Yebra A, Demidova MM, Platonov P, Martínez JP, Laguna P ( 2024 ) . T-Wave Peak-to-End Changes Quantified by Time-Warping Predicts Ventricular Fibrillation in a Porcine Myocardial Infarction Model . IEEE Transactions on Biomedical Engineering vol. 71 , ( 10 ) 2968 - 2977 .

Sanghvi MM, Ramírez J, Chadalavada S, Aung N, Munroe PB, Donos N, Petersen SE ( 2024 ) . The Association Between Periodontal Disease and Cardiovascular Disease . JACC: Advances vol. 3 , ( 10 ) Article 101241 , 101241 - 101241 .

Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT et al. ( 2024 ) . Genome‐Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants . Journal of the American Heart Association vol. 13 , ( 17 ) Article e034760 ,

Ramírez J, van Duijvenboden S, Young WJ, Chen Y, Usman T, Orini M, Lambiase PD, Tinker A et al. ( 2024 ) . Fine mapping of candidate effector genes for heart rate . Human Genetics vol. 143 , ( 9-10 ) 1207 - 1221 .

Madrid J, Munroe P, Duijvenboden S, Mincholé A, Ramírez J ( 2024 ) . ECG-based unsupervised clustering in coronary artery disease associates with cardiovascular events . Journal of Electrocardiology vol. 85 , 3 - 4 .

Ramírez J, Young WJ, van Duijvenboden S, Munroe PB ( 2024 ) . PO-01-089 PREDICTION OF ATRIAL AND VENTRICULAR ARRHYTHMIAS USING MULTIPLE CARDIOVASCULAR RISK FACTOR POLYGENIC RISK SCORES . Heart Rhythm vol. 21 , ( 5 ) S209 - S209 .

Madrid J, van Duijvenboden S, Munroe PB, Minchole A, Ramírez J ( 2024 ) . PO-02-049 ECG-BASED UNSUPERVISED CLUSTERING IN CORONARY ARTERY DISEASE DETECTS AND PREDICTS HEART FAILURE . Heart Rhythm vol. 21 , ( 5 ) S278 - S278 .

Naderi H, Ramírez J, van Duijvenboden S, Pujadas ER, Aung N, Wang L, Chamling B, Dörr M et al. ( 2024 ) . Diagnostic and prognostic value of ECG-predicted hypertension-mediated left ventricular hypertrophy using machine learning .

Munroe PB, Aung N, Ramírez J ( 2024 ) . Genetic analysis of cardiac dynamic flow volumes identifies loci mapping aortic root size . Nature Genetics vol. 56 , ( 2 ) 197 - 199 .

Sanghvi M, Ramirez J, Petersen S, Aung N, Munroe P ( 2024 ) . Investigation of the Modulatory Effect of Physical Activity on Genetic Variants Associated with Left Ventricular Mass . Journal of Cardiovascular Magnetic Resonance vol. 26 , Article 100322 , 100322 - 100322 .

van Duijvenboden S, Ramírez J, Orini M, Aung N, Petersen SE, Doherty A, Tinker A, Munroe PB et al. ( 2023 ) . Prognostic Significance of Different Ventricular Ectopic Burdens During Submaximal Exercise in Asymptomatic UK Biobank Subjects . Circulation vol. 148 , ( 24 ) 1932 - 1944 .

Ramírez J, Miguel A, van Duijvenboden S, Orini M, J. Young W, Tinker A, Lambiase P, B. Munroe P et al. . A Multi-layer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population . Computing in Cardiology Conference (CinC) . Conference: 2023 Computing in Cardiology Conference

Gómez Fonseca N, Ramírez J, Martin A, M. Demidova M, Platonov P, Pablo Martínez J, Laguna P . Changes in T-peak-to-T-end Morphology Measured by Time-Warping Are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model . Computing in Cardiology Conference (CinC) . Conference: 2023 Computing in Cardiology Conference

Madrid J, Munroe P, Van Duijvenboden S, Ramírez J, Mincholé A . ECG-Based Unsupervised Clustering in Coronary Artery Disease Associates with Ventricular Arrhythmia . Computing in Cardiology Conference (CinC) . Conference: 2023 Computing in Cardiology Conference

Orini M, van Duijvenboden S, Ramírez J, Young W, Tinker A, Munroe P, Lambiase P . Ultra-Short Beat-to-Beat Repolarization Variability Predicts Cardiovascular Events in Individuals without Cardiovascular Disease . Computing in Cardiology Conference (CinC) . Conference: 2023 Computing in Cardiology Conference

Ramirez J, Martinez JP, Van Duijvenboden S, Tinker A, Lambiase P, Orini M, Munroe PB, Miguel A ( 2023 ) . Combining hypothesis-driven ECG indices with machine learning improves ventricular arrhythmic risk prediction in a low-risk population . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.2914 ,

Orini M, Van Duijvenboden S, Young WJ, Ramirez J, Jones AR, Tinker A, Munroe PB, Lambiase PD ( 2023 ) . Ultra-short heart rate variability over 15 seconds is associated with increased long-term risk of cardiovascular disease . European Heart Journal vol. 44 , ( Supplement_2 ) Article ehad655.2912 ,

Orini M, van Duijvenboden S, Young WJ, Ramírez J, Jones AR, Hughes AD, Tinker A, Munroe PB et al. ( 2023 ) . Long-term association of ultra-short heart rate variability with cardiovascular events . Scientific Reports vol. 13 , ( 1 ) Article 18966 ,

Gómez N, Ramírez J, Martínez JP, Laguna P ( 2023 ) . Time-Warping Analysis of the T-Wave Peak-to-End Interval to Quantify Ventricular Repolarization Dispersion During Ischemia . IEEE Journal of Biomedical and Health Informatics vol. 27 , ( 11 ) 5314 - 5325 .

van Duijvenboden S, Ramírez J, Young WJ, Olczak KJ, Ahmed F, Alhammadi MJAY, Bell CG, Morris AP et al. ( 2023 ) . Integration of genetic fine-mapping and multi-omics data reveals candidate effector genes for hypertension . The American Journal of Human Genetics vol. 110 , ( 10 ) 1718 - 1734 .

Madrid J, Ramírez J, Mincholé A ( 2023 ) . ECG-Based Unsupervised Clustering in Coronary Artery Disease Associates with Ventricular Arrhythmia . Jornada de Jóvenes Investigadores del I3A vol. 11 ,

Orini M, Duijvenboden SV, Young WJ, Ramírez J, Jones AR, Hughes A, Tinker A, Munroe PB et al. ( 2023 ) . Long-term association of 15-second heart rate variability with cardiovascular events .

Naderi H, Ramirez J, Van Duijvenboden S, Ruiz Pujadas E, Aung N, Wang L, Chahal CAA, Lekadir K et al. ( 2023 ) . Classifying hypertension mediated left ventricular hypertrophy phenotypes from the 12-lead electrocardiogram using machine learning . European Heart Journal - Cardiovascular Imaging vol. 24 , ( Supplement_1 ) Article jead119.054 ,

Sanghvi MM, Aung N, Ramirez J, Munroe PB, Petersen SE ( 2023 ) . The association between non-lipid metabolomic biomarkers and prognostically important left ventricular phenotypes . European Heart Journal - Cardiovascular Imaging vol. 24 , ( Supplement_1 ) Article jead119.284 ,

Naderi H, Ramírez J, van Duijvenboden S, Pujadas ER, Aung N, Wang L, Anwar Ahmed Chahal C, Lekadir K et al. ( 2023 ) . Predicting left ventricular hypertrophy from the 12-lead electrocardiogram in the UK Biobank imaging study using machine learning . European Heart Journal - Digital Health vol. 4 , ( 4 ) 316 - 324 .

Graham SE, Clarke SL, Wu K-HH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I et al. ( 2023 ) . Author Correction: The power of genetic diversity in genome-wide association studies of lipids . Nature vol. 618 , ( 7965 ) E19 - E20 .

Young WJ, Haessler J, Benjamins J-W, Repetto L, Yao J, Isaacs A, Harper AR, Ramirez J et al. ( 2023 ) . Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease . Nature Communications vol. 14 , ( 1 ) Article 1411 ,

van Duijvenboden S, Ramírez J, Orini M, Doherty A, Tinker A, Munroe PB, Lambiase PD ( 2023 ) . Prognostic Significance of Different Ventricular Ectopic Burdens During Exercise in Asymptomatic UK Biobank Subjects .

Orini M, van Duijvenboden S, Young WJ, Ramírez J, Jones AR, Tinker A, Munroe PB, Lambiase PD ( 2023 ) . Premature atrial and ventricular contractions detected on wearable-format electrocardiograms and prediction of cardiovascular events . European Heart Journal - Digital Health vol. 4 , ( 2 ) 112 - 118 .

van Duijvenboden S, Ramírez J, Young WJ, Olczak KJ, Ahmed F, Alhammadi MJAY, Bell CG, Morris AP et al. ( 2023 ) . Integration of genetic fine-mapping and multi-omics data reveals candidate effector genes for hypertension .

Gómez Fonseca N, Ramírez J, Laguna P, Pablo Martínez\ J . Time-Warping Based End-of-T-Wave Shape Marker Reflects Repolarization Changes During Ischemia . Computing in Cardiology Conference (CinC) . Conference: 2022 Computing in Cardiology Conference

Orini M, van Duijvenboden S, Ramirez J, Tinker A, Munroe P, Lambiase\ P . Uncoupling Between Heart Rate Variability and Heart Rate During Exercise and Recovery as a Predictor of Cardiovascular Events . Computing in Cardiology Conference (CinC) . Conference: 2022 Computing in Cardiology Conference

( 2022 ) . Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis . Genome Biology vol. 23 , ( 1 ) Article 268 ,

( 2022 ) . A saturated map of common genetic variants associated with human height . Nature vol. 610 , ( 7933 ) 704 - 712 .

Ramírez J, van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Orini M, Munroe PB ( 2022 ) . Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors . Circulation: Genomic and Precision Medicine vol. 15 , ( 5 )

Ramírez J, Kiviniemi A, van Duijvenboden S, Tinker A, Lambiase PD, Junttila J, Perkiömäki JS, Huikuri HV et al. ( 2022 ) . ECG T‐Wave Morphologic Variations Predict Ventricular Arrhythmic Risk in Low‐ and Moderate‐Risk Populations . Journal of the American Heart Association vol. 11 , ( 17 ) Article e025897 ,

Young WJ, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody JA, Salman R et al. ( 2022 ) . Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways . Nature Communications vol. 13 , ( 1 ) Article 5144 ,

Palmieri F, Gomis P, Ferreira D, Pueyo E, Martinez JP, Laguna P, Ramirez J ( 2022 ) . Weighted Time Warping Improves T-Wave Morphology Markers Clinical Significance . IEEE Transactions on Biomedical Engineering vol. 69 , ( 9 ) 2787 - 2796 .

( 2022 ) . A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids . The American Journal of Human Genetics vol. 109 , ( 8 ) 1366 - 1387 .

Ramírez J, Van Duijvenboden S, Young W, Tinker A, Lambiase P, Orini M, Munroe P ( 2022 ) . Prediction of coronary artery disease and major adverse cardiovascular events using clinical and genetic risk scores for cardiovascular risk factors . Atherosclerosis vol. 355 , 3 - 4 .

Rezaei MJ, Woodward JR, Ramirez J, Munroe P ( 2022 ) . Combination of Isolation Forest, SMOTE and Ensemble Learning for the classification of Atrial Fibrillation and Ventricular Arrhythmia . 2021 International Conference on Biomedical Innovations and Applications (BIA) . Conference: 2021 International Conference on Biomedical Innovations and Applications (BIA) from: 02/06/2022 to: 04/06/2022 , 45 - 50 .

Naderi H, Ramírez J, Van Duijvenboden S, Aung N, Fung K, Young W, Petersen S, Munroe P ( 2022 ) . PREDICTING THE PATTERN OF ANATOMICAL LEFT VENTRICULAR HYPERTROPHY USING ELECTROPHYSIOLOGICAL BIOMARKERS FROM THE ECG QRS COMPLEX IN HYPERTENSIVE INDIVIDUALS FROM UK BIOBANK . Journal of Hypertension . vol. 40 , e5 - e5 .

( 2022 ) . A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries .

Naderi H, Ramirez J, van Duijvenboden S, Ruiz Pujadas E, Wang L, Lekadir K, Petersen S, Munroe P ( 2022 ) . Classifying hypertension mediated left ventricular hypertrophy patterns from the electrocardiogram using machine learning . JOURNAL OF HUMAN HYPERTENSION . vol. 36 , 4 - 4 .

Ramirez J, van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Orini M, Munroe PB ( 2022 ) . Prediction of coronary artery disease: Do risk factor genetic risk scores add value? . EUROPEAN JOURNAL OF HUMAN GENETICS . vol. 30 , 188 - 189 .

( 2021 ) . Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis .

( 2021 ) . The power of genetic diversity in genome-wide association studies of lipids . Nature vol. 600 , ( 7890 ) 675 - 679 .

( 2021 ) . A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids .

Young WJ, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody JA, Salman R et al. ( 2021 ) . Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization .

Fung K, Biasiolli L, Hann E, Lukaschuk E, Ramírez J, Duijvenboden SV, Aung N, Paiva JM et al. ( 2021 ) . 9 Identification of thirty novel loci for cardiovascular magnetic resonance derived aortic distensibility in the UK Biobank . Abstracts . Conference: British Society of Cardiovascular Magnetic Resonance 2021 Annual MeetingA6 - A8 .

Tardajos Ayllón B, Basu J, Burrage M, Kotanidis CP, Ramirez J, Coyle C ( 2021 ) . The British Cardiovascular Society Young Investigator Award 2021 . Heart vol. 107 , ( 22 ) 1844 - 1845 .

Palmieri F, Gomis P, Ruiz JE, Ferreira D, Pueyo E, Martinez JP, Laguna P, Ramirez J ( 2021 ) . Weighted Time Warping T-Wave Analysis Robust to Delineation Errors: Clinical Implications . 2021 Computing in Cardiology (CinC) . Conference: 2021 Computing in Cardiology (CinC) from: 13/09/2021 to: 15/09/2021 , 1 - 4 .

Bukhari HA, Palmieri F, Ramirez J, Laguna P, Ruiz JE, Ferreira D, Potse M, Sanchez C et al. ( 2021 ) . Characterization of T Wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship With Serum Electrolyte Levels and Heart Rate . IEEE Transactions on Biomedical Engineering vol. 68 , ( 8 ) 2467 - 2478 .

van Duijvenboden S, Ramírez J, Young WJ, Orini M, Mifsud B, Tinker A, Lambiase PD, Munroe PB ( 2021 ) . Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders . Human Molecular Genetics vol. 30 , ( 24 ) 2513 - 2523 .

Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martín-Yebra A, Pueyo E, Martínez JP, Ramírez J et al. ( 2021 ) . ECG-based monitoring of blood potassium concentration: Periodic versus principal component as lead transformation for biomarker robustness . Biomedical Signal Processing and Control vol. 68 , Article 102719 , 102719 - 102719 .

Ramírez J, Duijvenboden SV, Young WJ, Orini M, Jones AR, Lambiase PD, Munroe PB, Tinker A ( 2021 ) . Analysing electrocardiographic traits and predicting cardiac risk in UK biobank . JRSM Cardiovascular Disease vol. 10 , Article 20480040211023664 ,

van Duijvenboden S, Ramirez J, Orini M, Tinker A, Munroe P, Lambiase P ( 2021 ) . 85 Prognostic value of premature ventricular complexes during exercise stress testing in 56,000 individuals without known structural heart disease from UK biobank: is a single ectopic prognostic? . Cardiac rhythm management . Conference: British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021A68 - A68 .

Young W, Warren H, Mook-Kanamori D, Ramirez J, van Duijvenboden S, Orini M, Tinker A, van Heemst D et al. ( 2021 ) . BS8 Genetically-determined serum calcium levels influence markers of ventricular repolarisation: a mendelian randomisation study . Basic science . Conference: British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021A159.2 - A160 .

Ramírez J ( 2021 ) . E Abnormal resting ECG t-wave morphology predicts ventricular arrhythmic risk in a large “low-risk” cohort . Young investigators award . Conference: British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 7–10 June 2021A178 - A178 .

Young WJ, Warren HR, Mook-Kanamori DO, Ramírez J, van Duijvenboden S, Orini M, Tinker A, van Heemst D et al. ( 2021 ) . Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank . Circulation: Genomic and Precision Medicine vol. 14 , ( 3 ) Article e003231 ,

Rezaei MJ, Woodward JR, Ramírez J, Munroe P ( 2021 ) . A Novel Two-Stage Heart Arrhythmia Ensemble Classifier . Computers vol. 10 , ( 5 ) 60 - 60 .

Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martín-Yebra A, Pueyo E, Martínez JP, Ramírez J et al. ( 2021 ) . Nonlinear T-Wave Time Warping-Based Sensing Model for Non-Invasive Personalised Blood Potassium Monitoring in Hemodialysis Patients: A Pilot Study . Sensors vol. 21 , ( 8 ) 2710 - 2710 .

Mensah-Kane J, Schmidt AF, Hingorani AD, Finan C, Chen Y, van Duijvenboden S, Orini M, Lambiase PD et al. ( 2021 ) . No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis . Frontiers in Genetics vol. 12 , Article 569323 ,

Palmieri F, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martín-Yebra A, Bukhari HA, Pueyo E et al. ( 2021 ) . Monitoring blood potassium concentration in hemodialysis patients by quantifying T-wave morphology dynamics . Scientific Reports vol. 11 , ( 1 ) Article 3883 ,

Young WJ, van Duijvenboden S, Ramírez J, Jones A, Tinker A, Munroe PB, Lambiase PD, Orini M ( 2021 ) . A Method to Minimise the Impact of ECG Marker Inaccuracies on the Spatial QRS-T angle: Evaluation on 1,512 Manually Annotated ECGs . Biomedical Signal Processing and Control vol. 64 , Article 102305 , 102305 - 102305 .

Ramirez J, van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Orini M, Munroe PB ( 2021 ) . Prediction of Coronary Artery Disease using Traditional and Genetic Risk Scores for Cardiovascular Risk Factors . GENETIC EPIDEMIOLOGY . vol. 45 , 783 - 783 .

Palmieri F, Gomis P, Esteban Ruiz J, Ferreira D, Pueyo E, Pablo Martinez J, Laguna P, Ramirez J ( 2021 ) . Weighted TimeWarping T-Wave Analysis Robust to Delineation Errors: Clinical Implications . 2021 COMPUTING IN CARDIOLOGY (CINC) .

van Duijvenboden S, Ramírez J, J. Young W, Tinker A, B. Munroe P, D. Lambiase P, Orini M . Evaluating the Impact of Physiological Variability in Genome-Wide Association Studies of Resting Heart Rate . Computing in Cardiology Conference (CinC) . Conference: 2020 Computing in Cardiology Conference

Aung N, Young W, Van Duijvenboden S, Ramírez J, Petersen S, Munroe P . Genetic Architecture of Quantitative Cardiovascular Traits: Blood Pressure, ECG and Imaging Phenotypes . Computing in Cardiology Conference (CinC) . Conference: 2020 Computing in Cardiology Conference

Ramírez J, van Duijvenboden S, Young W, Tinker A, Lambiase P, Munroe P, Orini M . Interaction Between ECG and Genetic Markers of Coronary Artery Disease . Computing in Cardiology Conference (CinC) . Conference: 2020 Computing in Cardiology Conference

Palmieri F, Gomis P, Esteban Ruiz J, Ferreira D, Martin A, Pueyo E, Laguna P, Pablo Martínez J et al. . Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic versus Principal Component Analysis . Computing in Cardiology Conference (CinC) . Conference: 2020 Computing in Cardiology Conference

Ramírez J, van Duijvenboden S, Tinker A, Lambiase P, Munroe P, Orini M . Sex Differences in the Morphology of RR-Matched T-waves . Computing in Cardiology Conference (CinC) . Conference: 2020 Computing in Cardiology Conference

Young W, Ramírez J, van Duijvenboden S, Tinker A, Lambiase P, Munroe P, Orini M . Will Genetic Data Significantly Change Cardiovascular Risk Prediction in Daily Practice? . Computing in Cardiology Conference (CinC) . Conference: 2020 Computing in Cardiology Conference

Ramírez J, Tinker A ( 2020 ) . Ventricular Restitution Predicts Paroxysmal Atrial Fibrillation in Horses . Function vol. 2 , ( 1 ) Article zqaa038 ,

Rezaei MJ, Woodward JR, Ramirez J, Munroe P ( 2020 ) . Data Augmentation for Heart Arrhythmia Classification . 2020 IEEE 32nd International Conference on Tools with Artificial Intelligence (ICTAI) . Conference: 2020 IEEE 32nd International Conference on Tools with Artificial Intelligence (ICTAI) from: 09/11/2020 to: 11/11/2020 , 929 - 934 .

Weng L-C, Hall AW, Choi SH, Jurgens SJ, Haessler J, Bihlmeyer NA, Grarup N, Lin H et al. ( 2020 ) . Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation . Circulation: Genomic and Precision Medicine vol. 13 , ( 5 ) 387 - 395 .

García-González J, Ramírez J, Howard DM, Brennan CH, Munroe PB, Keers R ( 2020 ) . The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank . Translational Psychiatry vol. 10 , ( 1 ) Article 330 ,

van Duijvenboden S, Ramírez J, Young WJ, Mifsud B, Orini M, Tinker A, Munroe PB, Lambiase PD ( 2020 ) . Genetic Basis and Prognostic Value of Exercise QT Dynamics . Circulation: Genomic and Precision Medicine vol. 13 , ( 4 ) Article e002774 ,

Ramírez J, van Duijvenboden S, Young WJ, Orini M, Lambiase PD, Munroe PB, Tinker A ( 2020 ) . Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval . The American Journal of Human Genetics vol. 106 , ( 6 ) 764 - 778 .

Ntalla I, Weng L-C, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD et al. ( 2020 ) . Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction . Nature Communications vol. 11 , ( 1 ) Article 2542 ,

Fung K, Biasiolli L, Hann E, Ramirez J, Lukaschuk E, Aung N, Paiva J, Werys K et al. ( 2019 ) . 3.2 First Genome-Wide Association Study of Cardiovascular Magnetic Resonance Derived Aortic Distensibility Reveals 7 Loci . Artery Research . vol. 25 , S21 - S22 .

Cabrera CP, Pazoki R, Giri A, Hellwege JN, Evangelou E, Ramirez J, Wain LV, Tzoulaki I et al. ( 2020 ) . Multi-trait genome-wide association analysis of blood pressure identifies 45 additional loci . EUROPEAN JOURNAL OF HUMAN GENETICS . vol. 28 , 105 - 105 .

Palmieri F, Gomis P, Esteban Ruiz J, Bergasa B, Dina F, Martin A, Hassaan Ahamed S, Pueyo E et al. . T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients . Computing in Cardiology Conference (CinC) . Conference: 2019 Computing in Cardiology Conference

Hassaan Ahmed Bukhari S, Palmieri F, Ferreira D, Potse M, Ramırez J, Laguna P, Sanchez C, Pueyo E . Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels . Computing in Cardiology Conference (CinC) . Conference: 2019 Computing in Cardiology Conference

García-González J, Ramírez J, Howard DM, Brennan CH, Munroe PB, Keers R ( 2019 ) . The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank .

Ramírez J, van Duijvenboden S, Aung N, Laguna P, Pueyo E, Tinker A, Lambiase PD, Orini M et al. ( 2019 ) . Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics . Circulation: Arrhythmia and Electrophysiology vol. 12 , ( 10 ) Article e007549 ,

Munroe PB, Ramírez J, van Duijvenboden S ( 2019 ) . Resting Heart Rate and Type 2 Diabetes . Journal of the American College of Cardiology vol. 74 , ( 17 ) 2175 - 2177 .

Palmieri F, Ramírez J, Laguna P, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martín-Yebra A et al. ( 2019 ) . T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients . Computing in Cardiology . vol. 2019-September ,

Bukhari HA, Palmieri F, Ferreira D, Potse M, Ramírez J, Laguna P, Sánchez C, Pueyo E ( 2019 ) . Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels . Computing in Cardiology . vol. 2019-September ,

Ntalla I, Weng L-C, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD et al. ( 2019 ) . Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction .

Fung K, Ramírez J, Warren HR, Aung N, Lee AM, Tzanis E, Petersen SE, Munroe PB ( 2019 ) . Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants . Scientific Reports vol. 9 , ( 1 ) Article 9143 ,

Ramirez J, van Duijvenboden S, Tinker A, Lambiase P, Orini M, Munroe PB ( 2019 ) . 21 The cardiovascular predictive value and genetic basis of T-wave morphology . Cardiac rhythm management . Conference: British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019A18.2 - A19 .

van Duijvenboden S, Ramirez J, Orini M, Tinker A, Munroe PB, Lambiase P ( 2019 ) . 22 Cardiac repolarization during exercise reveals independent prognostic information for cardiovascular risk prediction . Cardiac Rhythm Management . Conference: British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019A19 - A20 .

Ramírez J, van Duijvenboden S, Laguna P, Pueyo E, Tinker A, Lambiase P, Munroe P, Orini M . Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology . Computing in Cardiology Conference (CinC) . Conference: 2018 Computing in Cardiology Conference

Palmieri F, Pablo Martínez J, Burattini L, Ramírez J . T-Wave Morphology Restitution in Chronic Heart Failure Patients With Atrial Fibrillation . Computing in Cardiology Conference (CinC) . Conference: 2018 Computing in Cardiology Conference

Ramírez J, van Duijvenboden S, Orini M, Tinker A, Munroe PB, Lambiase PD ( 2018 ) . 23T-wave morphology restitution predicts arrhythmic risk in the UK biobank cohort . EP Europace vol. 20 , ( suppl_4 ) iv10 - iv11 .

van Duijvenboden S, Ramírez J, Orini M, Tinker A, Munroe PB, Lambiase PD ( 2018 ) . 2QT interval and exercise qt dynamics from 58,852 individuals in UK biobank predict ventricular arrhythmias and heart failure . EP Europace vol. 20 , ( suppl_4 ) iv1 - iv1 .

Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J et al. ( 2018 ) . Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 . Genome Biology vol. 19 , ( 1 ) Article 87 ,

Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al. ( 2018 ) . Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system . Nature Communications vol. 9 , ( 1 ) Article 1947 ,

Ramírez J, Orini M, Mincholé A, Monasterio V, Cygankiewicz I, Bayés de Luna A, Martínez JP, Laguna P et al. ( 2017 ) . Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model . PLOS ONE vol. 12 , ( 10 ) e0186152 - e0186152 .

Ram�rez J, Orini M, Pueyo E, Laguna P . Comparison of ECG T-wave Duration and Morphology Restitution Markers for Sudden Cardiac Death Prediction in Chronic Heart Failure . Computing in Cardiology Conference (CinC) . Conference: 2017 Computing in Cardiology Conference

Ram�rez J, Orini M, Pueyo E, Laguna P . T-wave Morphology Restitution Dependency with Heart Rate Range and Its Association with Sudden Cardiac Death in Chronic Heart Failure . Computing in Cardiology Conference (CinC) . Conference: 2017 Computing in Cardiology Conference

Ramirez J, Orini M, Tucker JD, Pueyo E, Laguna P ( 2017 ) . Variability of Ventricular Repolarization Dispersion Quantified by Time-Warping the Morphology of the T-Waves . IEEE Transactions on Biomedical Engineering vol. 64 , ( 7 ) 1619 - 1630 .

Ramírez J, Orini M, Pueyo E, Laguna P ( 2018 ) . Quantification of T-wave Morphological Variability Using Time-warping Methods . 478 - 481 .

Ramírez J, Orini M, Mincholé A, Monasterio V, Cygankiewicz I, Bayés de Luna A, Martínez JP, Pueyo E et al. ( 2017 ) . T‐Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure . Journal of the American Heart Association vol. 6 , ( 5 ) Article e005310 ,

Ramirez J, Orini M, Tucker JD, Pueyo E, Laguna P . An Index for T:wave Pointwise Amplitude Variability Quantification . 2016 Computing in Cardiology Conference (CinC) . Conference: 2016 Computing in Cardiology Conference

Lenis G, Menges R, Ramirez J, Cygankiewicz I, Bayes de Luna A, Martinez JP, Laguna P, Doessel O . Postextrasystolic T Wave Change to Stratify Risk of Pump Failure Death in Patients with Chronic Heart Failure . 2016 Computing in Cardiology Conference (CinC) . Conference: 2016 Computing in Cardiology Conference

Ramírez J, Monasterio V, Mincholé A, Llamedo M, Lenis G, Cygankiewicz I, Bayés de Luna A, Malik M et al. ( 2015 ) . Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers . Journal of Electrocardiology vol. 48 , ( 4 ) 551 - 557 .

Ramírez J, Laguna P, Bayés de Luna A, Malik M, Pueyo E ( 2015 ) . Erratum: QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death . Journal of Electrocardiology vol. 48 , ( 1 ) 128 - 129 .

Ramírez J, Laguna P, Bayés de Luna A, Malik M, Pueyo E ( 2014 ) . QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death . Journal of Electrocardiology vol. 47 , ( 6 ) 842 - 848 .

Ramirez J, Cygankiewicz I, Laguna P, Malik M, Pueyo E ( 2014 ) . Circadian Pattern and Sex Differences of QT/RR and T-peak-to-end/RR Curvatures and Slopes in Chronic Heart Failure Patients . 2014 COMPUTING IN CARDIOLOGY CONFERENCE (CINC), VOL 41 . vol. 41 , 173 - 176 .

Ramirez J, Minchole A, Bolea J, Laguna P, Pueyo E ( 2013 ) . Prediction of Sudden Cardiac Death in Chronic Heart Failure Patients by Analysis of Restitution Dispersion . 2013 COMPUTING IN CARDIOLOGY CONFERENCE (CINC) . vol. 40 , 1 - 4 .

Ramirez J, Minchole A, Laguna P, Pueyo E ( 2012 ) . Characterization of Cardiac Repolarization Response to Heart Rate Changes Provoked by a Tilt Test . 2012 COMPUTING IN CARDIOLOGY (CINC), VOL 39 . vol. 39 , 673 - 676 .