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Research

Publications: DR Mihir Sanghvi

Nicholls HL, Vargas JD, Sanghvi MM, Ahn H-S, Chahal CAA, Khanji MY, Petersen SE, Munroe PB et al. ( 2026 ) . Genome-wide analysis of cardiac ventricular phenotypes reveals novel loci and therapeutic targets for heart failure . Nature Communications
Sanghvi MM, Munroe PB ( 2026 ) . Genetic studies of aortic stenosis provide a broader view of narrowed valves . Nature Cardiovascular Research1 - 3 .
Nicole Madrid J, Sanghvi M, Young W, van Duijvenboden S, Munroe P, Ramírez J, Mincholé A . Unsupervised ECG Clustering Reveals Distinct Associations with Cardiac Magnetic Resonance Features . 2016 Computing in Cardiology Conference (CinC) . Conference: 2025 Computing in Cardiology Conference (CinC) vol. 52 ,
Young WJ, Sanghvi MM, Ramírez J, Orini M, van Duijvenboden S, Warren HR, Tinker A, Lambiase PD et al. ( 2025 ) . Relationships of Circulating Plasma Metabolites With the QT Interval in a Large Population Cohort . Circulation Genomic and Precision Medicine vol. 18 , ( 5 )
Chadalavada S, Salih A, Naderi H, Rauseo E, Cooper J, Duijvenboden SV, Chahal AA, Dabbagh GS et al. ( 2025 ) . Prospective electrocardiographic and cardiovascular magnetic resonance alterations in the UK Biobank coronavirus disease 2019 repeat imaging study . Journal of Cardiovascular Magnetic Resonance vol. 27 , ( 2 )
Madrid J, Sanghvi M, Young WJ, van Duijvenboden S, Munroe PB, Ramírez J, Mincholé A ( 2025 ) . La agrupación no supervisada de electrocardiogramas revela asociaciones con características de resonancia magnética cardíaca . Jornadas de jóvenes investigadores del I3A vol. 13 ,
Sanghvi MM, Petersen SE ( 2025 ) . Epicardial adipose tissue: from cardiac wrapper to remodeller? . European Journal of Preventive Cardiology
Sanghvi MM, Young WJ, Naderi H, Burns R, Ramírez J, Bell CG, Munroe PB ( 2025 ) . Using Genomics to Develop Personalized Cardiovascular Treatments . Arteriosclerosis Thrombosis and Vascular Biology vol. 45 , ( 6 ) 866 - 881 .
Sanghvi MM, Dhall E, Anwar A Chahal C, O'Mahony C, Mohiddin SA, Savvatis K, Ricci F, Munroe PB et al. ( 2025 ) . Hypertrophic cardiomyopathy management: a systematic review of the clinical practice guidelines and recommendations . European Heart Journal - Quality of Care and Clinical Outcomes vol. 11 , ( 7 ) 919 - 933 .
Chadalavada S, Rauseo E, Salih A, Naderi H, Khanji M, Vargas JD, Lee AM, Amir-Kalili A et al. ( 2024 ) . Quality control of cardiac magnetic resonance imaging segmentation, feature tracking, aortic flow, and native T1 analysis using automated batch processing in the UK Biobank study . European Heart Journal - Imaging Methods and Practice vol. 2 , ( 3 )
Sanghvi MM, Ramírez J, Chadalavada S, Aung N, Munroe PB, Donos N, Petersen SE ( 2024 ) . The Association Between Periodontal Disease and Cardiovascular Disease Insights From Imaging, Observational, and Genetic Data . JACC Advances vol. 3 , ( 10 )
Sanghvi MM, Lima JAC, Petersen SE ( 2024 ) . A history of cardiovascular magnetic resonance imaging in clinical practice and population science . Frontiers in Cardiovascular Medicine vol. 11 ,
Aung N, Bartoli A, Rauseo E, Cortaredona S, Sanghvi MM, Fournel J, Ghattas B, Khanji MY et al. ( 2024 ) . Left Ventricular Trabeculations at Cardiac MRI: Reference Ranges and Association with Cardiovascular Risk Factors in UK Biobank . Radiology vol. 311 , ( 1 )
Wong MYZ, Vargas JD, Naderi H, Sanghvi MM, Raisi-Estabragh Z, Suinesiaputra A, Bonazzola R, Attar R et al. ( 2024 ) . Concurrent Left Ventricular Myocardial Diffuse Fibrosis and Left Atrial Dysfunction Strongly Predict Incident Heart Failure . JACC Cardiovascular Imaging vol. 17 , ( 5 ) 560 - 562 .
Sanghvi MM, Aung N, Ramirez J, Munroe PB, Petersen SE ( 2023 ) . The association between non-lipid metabolomic biomarkers and prognostically important left ventricular phenotypes . European Heart Journal - Cardiovascular Imaging vol. 24 , ( Supplement_1 )
Aung N, Wong MYZ, Vargas JD, Naderi H, Sanghvi MM, Raisi-Estabragh Z, Suinesiaputra A, Bonazzola R et al. ( 2023 ) . Concurrent left ventricular myocardial diffuse fibrosis and left atrial dysfunction strongly predicts incident heart failure and all-cause mortality . European Heart Journal . vol. 44 ,
Aung N, Vargas JD, Yang C, Fung K, Sanghvi MM, Piechnik SK, Neubauer S, Manichaikul A et al. ( 2022 ) . Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function . Nature Genetics vol. 54 , ( 6 ) 783 - 791 .
Sanghvi MM, Vargas JD, Suinesiaputra A, Bonazzola R, Attar R, Ravikumar N, Wong M, Naderi H et al. ( 2021 ) . 13 The association between cardiovascular risk factors and left atrial structure and phasic function . Heart . Conference: Abstracts vol. 107 , a11 - a12 .
Fung K, Biasiolli L, Hann E, Lukaschuk E, Ramírez J, van Duijvenboden S, Aung N, Paiva JM et al. ( 2021 ) . 9 Identification of thirty novel loci for cardiovascular magnetic resonance derived aortic distensibility in the UK Biobank . Heart . Conference: Abstracts vol. 107 , a6 - a8 .
Sanghvi MM, Jones DM, Kalindjian J, Monkhouse C, Schilling RJ, Ahluwalia N ( 2021 ) . The utility of implantable loop recorders in patient management: an age- and indication-stratified study in the outpatient-implant era . European Heart Journal - Quality of Care and Clinical Outcomes vol. 8 , ( 7 ) 770 - 777 .
Curta A, Hetterich H, Schinner R, Lee AM, Sommer W, Aung N, Sanghvi MM, Fung K et al. ( 2021 ) . Subclinical Changes in Cardiac Functional Parameters as Determined by Cardiovascular Magnetic Resonance (CMR) Imaging in Sleep Apnea and Snoring: Findings from UK Biobank . Medicina vol. 57 , ( 6 )
Simon J, Fung K, Kolossváry M, Sanghvi MM, Aung N, Paiva JM, Lukaschuk E, Carapella V et al. ( 2020 ) . Sex-specific associations between alcohol consumption, cardiac morphology, and function as assessed by magnetic resonance imaging: insights form the UK Biobank Population Study . European Heart Journal - Cardiovascular Imaging vol. 22 , ( 9 ) 1009 - 1016 .
Aung N, Sanghvi MM, Piechnik SK, Neubauer S, Munroe PB, Petersen SE ( 2020 ) . The Effect of Blood Lipids on the Left Ventricle A Mendelian Randomization Study . Journal of the American College of Cardiology vol. 76 , ( 21 ) 2477 - 2488 .
Raisi‐Estabragh Z, Biasiolli L, Cooper J, Aung N, Fung K, Paiva JM, Sanghvi MM, Thomson RJ et al. ( 2020 ) . Poor Bone Quality is Associated With Greater Arterial Stiffness: Insights From the UK Biobank . Journal of Bone and Mineral Research vol. 36 , ( 1 ) 90 - 99 .
Doimo S, Ricci F, Aung N, Cooper J, Boubertakh R, Sanghvi MM, Sinagra G, Petersen SE ( 2020 ) . Tissue-tracking in the assessment of late gadolinium enhancement in myocarditis and myocardial infarction . Magnetic Resonance Imaging vol. 73 , 62 - 69 .
Sanghvi M, Neemuchwala H, Thekiya MH, Papal D ( 2020 ) . Design and Analysis of ‘Kangaroo’ Boots . Proceedings of International Conference on Intelligent Manufacturing and Automation , Springer Nature
Ajugia K ( 2020 ) . Numerical Comparison of Tube Bank Pressure Drop of an SHTX Using Elliptical and Flat Face Header with Different Nozzle Positions . Proceedings of International Conference on Intelligent Manufacturing and Automation , Springer Nature
Chen C, Bai W, Davies RH, Bhuva AN, Manisty CH, Augusto JB, Moon JC, Aung N et al. ( 2020 ) . Improving the Generalizability of Convolutional Neural Network-Based Segmentation on CMR Images . Frontiers in Cardiovascular Medicine vol. 7 ,
Aung N, Doimo S, Ricci F, Sanghvi MM, Pedrosa C, Woodbridge SP, Al-Balah A, Zemrak F et al. ( 2020 ) . Prognostic Significance of Left Ventricular Noncompaction . Circulation Cardiovascular Imaging vol. 13 , ( 1 ) e009712 - e009712 .
Elmahi E, Sanghvi MM, Jones A, Aye CYL, Lewandowski AJ, Aung N, Cooper JA, Paiva JM et al. ( 2019 ) . Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK Biobank . PLOS ONE vol. 14 , ( 10 )
Elmahi E, Sanghvi MM, Jones A, Aye CYL, Lewandowski AJ, Aung N, Cooper JA, Paiva JM et al. ( 2019 ) . P2249Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK biobank . European Heart Journal . vol. 40 ,
Hann E, Biasiolli L, Zhang Q, Popescu IA, Werys K, Lukaschuk E, Carapella V, Paiva JM et al. ( 2019 ) . Quality Control-Driven Image Segmentation Towards Reliable Automatic Image Analysis in Large-Scale Cardiovascular Magnetic Resonance Aortic Cine Imaging . Lecture Notes in Computer Science . vol. 11765 , 750 - 758 .
Jensen MT, Fung K, Aung N, Sanghvi MM, Chadalavada S, Paiva JM, Khanji MY, de Knegt MC et al. ( 2019 ) . Changes in Cardiac Morphology and Function in Individuals With Diabetes Mellitus . Circulation Cardiovascular Imaging vol. 12 , ( 9 )
Ricci F, Aung N, Thomson R, Boubertakh R, Camaioni C, Doimo S, Sanghvi MM, Fung K et al. ( 2019 ) . Pulmonary blood volume index as a quantitative biomarker of haemodynamic congestion in hypertrophic cardiomyopathy . European Heart Journal - Cardiovascular Imaging vol. 20 , ( 12 ) 1368 - 1376 .
Mauger C, Gilbert K, Lee AM, Sanghvi MM, Aung N, Fung K, Carapella V, Piechnik SK et al. ( 2019 ) . Right ventricular shape and function: cardiovascular magnetic resonance reference morphology and biventricular risk factor morphometrics in UK Biobank . Journal of Cardiovascular Magnetic Resonance vol. 21 , ( 1 )
Chen C, Bai W, Davies RH, Bhuva AN, Manisty C, Moon JC, Aung N, Lee AM et al. ( 2019 ) . Improving the generalizability of convolutional neural network-based segmentation on CMR images .
Fung K, Biasiolli L, Aung N, Hann E, Paiva JM, Lukaschuk E, Sanghvi MM, Carapella V et al. ( 2019 ) . 282Reference values for aortic distensibility derived from UK Biobank cardiovascular magnetic resonance (CMR) imaging cohort . European Heart Journal - Cardiovascular Imaging . vol. 20 ,
Jensen MT, Fung K, Aung N, Sanghvi MM, Chadalavada S, Paiva JM, Khanji MY, De Knegt MC et al. ( 2019 ) . 347Early changes in cardiac morphology and function in individuals with diabetes and preserved ejection fraction detected by cardiovascular magnetic resonance tagging - The UK Biobank . European Heart Journal - Cardiovascular Imaging . vol. 20 ,
Sanghvi MM, Aung N, Cooper JA, Fung K, Paiva JM, Lukaschuk E, Piechnik SK, Neubauer S et al. ( 2019 ) . P145The effect of frailty on cardiovascular structure and function: insights from the UK Biobank . European Heart Journal - Cardiovascular Imaging . vol. 20 ,
Thomson RJ, Aung N, Sanghvi MM, Fung K, Paiva JM, Khanji MY, Lukaschuk E, Carapella V et al. ( 2019 ) . P419Cardiac structure and the QRISK cardiovascular risk prediction score: insights from the UK Biobank . European Heart Journal - Cardiovascular Imaging . vol. 20 ,
Aung N, Lee AM, Sanghvi MM, Fung K, Paiva JM, Thomson RJ, Khanji MY, Munro PB et al. ( 2019 ) . P622Automatic classification of CMR image sequences with convolutional neural networks . European Heart Journal - Cardiovascular Imaging . vol. 20 ,
Attar R, Pereañez M, Gooya A, Albà X, Zhang L, de Vila MH, Lee AM, Aung N et al. ( 2019 ) . Quantitative CMR population imaging on 20,000 subjects of the UK Biobank imaging study: LV/RV quantification pipeline and its evaluation . Medical Image Analysis vol. 56 , 26 - 42 .
Robinson R, Valindria VV, Bai W, Oktay O, Kainz B, Suzuki H, Sanghvi MM, Aung N et al. ( 2019 ) . Automated quality control in image segmentation: application to the UK Biobank cardiovascular magnetic resonance imaging study . Journal of Cardiovascular Magnetic Resonance vol. 21 , ( 1 )
Biasiolli L, Hann E, Lukaschuk E, Carapella V, Paiva JM, Aung N, Rayner JJ, Werys K et al. ( 2019 ) . Automated localization and quality control of the aorta in cine CMR can significantly accelerate processing of the UK Biobank population data . PLOS ONE vol. 14 , ( 2 )
Woodbridge SP, Aung N, Paiva JM, Sanghvi MM, Zemrak F, Fung K, Petersen SE ( 2019 ) . Physical activity and left ventricular trabeculation in the UK Biobank community-based cohort study . Heart vol. 105 , ( 13 )
Gilbert K, Bai W, Mauger C, Medrano-Gracia P, Suinesiaputra A, Lee AM, Sanghvi MM, Aung N et al. ( 2019 ) . Independent Left Ventricular Morphometric Atlases Show Consistent Relationships with Cardiovascular Risk Factors: A UK Biobank Study . Scientific Reports vol. 9 , ( 1 )
Robinson R, Valindria VV, Bai W, Oktay O, Kainz B, Suzuki H, Sanghvi MM, Aung N et al. ( 2019 ) . Automated Quality Control in Image Segmentation: Application to the UK Biobank Cardiac MR Imaging Study .
Aung N, Lee AM, Sanghvi MM, Fung K, Paiva JM, Thomson RJ, Khanji MY, Munro PB et al. ( 2019 ) . Automatic classification of CMR image sequences with convolutional neural networks . EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING . vol. 20 , 504 - 505 .
Thomson RJ, Aung N, Sanghvi MM, Fung K, Paiva JM, Khanji MY, Lukaschuk E, Carapella V et al. ( 2019 ) . Cardiac structure and the QRISK cardiovascular risk prediction score: insights from the UK Biobank .
Elmahi E, Sanghvi MM, Jones A, Aye CYL, Lewandowski AJ, Aung N, Cooper JA, Paiva JM et al. ( 2019 ) . Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK biobank . EUROPEAN HEART JOURNAL . vol. 40 , 1316 - 1316 .
Jensen MT, Fung K, Aung N, Sanghvi MM, Chadalavada S, Paiva JM, Khanji MY, De Knegt MC et al. ( 2019 ) . Early changes in cardiac morphology and function in individuals with diabetes and preserved ejection fraction detected by cardiovascular magnetic resonance tagging - The UK Biobank . EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING . vol. 20 , 251 - 252 .
Fung K, Biasiolli L, Aung N, Hann E, Paiva JM, Lukaschuk E, Sanghvi MM, Carapella V et al. ( 2019 ) . Reference values for aortic distensibility derived from UK Biobank cardiovascular magnetic resonance (CMR) imaging cohort . EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING . vol. 20 , 212 - 212 .
Sanghvi MM, Aung N, Cooper JA, Fung K, Paiva JM, Lukaschuk E, Piechnik SK, Neubauer S et al. ( 2019 ) . The effect of frailty on cardiovascular structure and function: insights from the UK Biobank . EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING . vol. 20 , 91 - 92 .
Bai W, Sinclair M, Tarroni G, Oktay O, Rajchl M, Vaillant G, Lee AM, Aung N et al. ( 2018 ) . Automated cardiovascular magnetic resonance image analysis with fully convolutional networks . Journal of Cardiovascular Magnetic Resonance vol. 20 , ( 1 )
Robinson R, Oktay O, Bai W, Valindria VV, Sanghvi MM, Aung N, Paiva JM, Zemrak F et al. ( 2018 ) . Real-Time Prediction of Segmentation Quality . Lecture Notes in Computer Science . vol. 11073 , 578 - 585 .
Aung N, Gilbert K, Suinesiaputra A, Lee A, Sanghvi MM, Zemrak F, Fung K, Paiva JM et al. ( 2018 ) . P3693Impact of cardiovascular risk factors on atlas-based left ventricular shape phenotypes . European Heart Journal . vol. 39 ,
Aung N, Sanghvi MM, Zemrak F, Lee AM, Cooper JA, Paiva JM, Thomson RJ, Fung K et al. ( 2018 ) . Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes . Circulation vol. 138 , ( 20 ) 2175 - 2186 .
Tang CX, Petersen SE, Sanghvi MM ( 2018 ) . Cardiovascular magnetic resonance imaging for amyloidosis: The state-of-the-art . Trends in Cardiovascular Medicine vol. 29 , ( 2 ) 83 - 94 .
Bai W, Sinclair M, Tarroni G, Oktay O, Rajchl M, Vaillant G, Lee AM, Aung N et al. ( 2018 ) . Automated cardiovascular magnetic resonance image analysis with fully convolutional networks .
Thomson RJ, Aung N, Sanghvi MM, Paiva JM, Lee AM, Zemrak F, Fung K, Pfeffer PE et al. ( 2018 ) . Variation in lung function and alterations in cardiac structure and function—Analysis of the UK Biobank cardiovascular magnetic resonance imaging substudy . PLOS ONE vol. 13 , ( 3 )
Beyer SE, Sanghvi MM, Aung N, Hosking A, Cooper JA, Paiva JM, Lee AM, Fung K et al. ( 2018 ) . Prospective association between handgrip strength and cardiac structure and function in UK adults . PLOS ONE vol. 13 , ( 3 )
Sanghvi MM, Aung N, Cooper JA, Paiva JM, Lee AM, Zemrak F, Fung K, Thomson RJ et al. ( 2018 ) . The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study . PLOS ONE vol. 13 , ( 3 )
Aung N, Gilbert K, Suinesiaputra A, Lee A, Sanghvi MM, Zemrak F, Fung K, Paiva JM et al. ( 2018 ) . Impact of cardiovascular risk factors on atlas-based left ventricular shape phenotypes . EUROPEAN HEART JOURNAL . vol. 39 , 772 - 773 .
Massey CJ, Troost TR, Anand VK ( 2018 ) . Persistent local demucosalization after endoscopic sinus surgery: A report of 3 cases . Ear, Nose & Throat Journal vol. 97 , ( 10-11 ) 354 - 361 .
Petersen SE, Sanghvi MM, Aung N, Cooper JA, Paiva JM, Zemrak F, Fung K, Lukaschuk E et al. ( 2017 ) . The impact of cardiovascular risk factors on cardiac structure and function: Insights from the UK Biobank imaging enhancement study . PLOS ONE vol. 12 , ( 10 )
Aung N, Woodbridge SP, Paiva JM, Sanghvi MM, Zemrak F, Cooper JA, Thomson RJ, Fung K et al. ( 2017 ) . P3992Relationship between left ventricular trabeculation and physical activity in a middle-aged population cohort . European Heart Journal . vol. 38 ,
Suinesiaputra A, Sanghvi MM, Aung N, Paiva JM, Zemrak F, Fung K, Lukaschuk E, Lee AM et al. ( 2017 ) . Fully-automated left ventricular mass and volume MRI analysis in the UK Biobank population cohort: evaluation of initial results . The International Journal of Cardiovascular Imaging vol. 34 , ( 2 ) 281 - 291 .
Petersen SE, Aung N, Sanghvi MM, Zemrak F, Fung K, Paiva JM, Francis JM, Khanji MY et al. ( 2017 ) . Reference ranges for cardiac structure and function using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort . Journal of Cardiovascular Magnetic Resonance vol. 19 , ( 1 )
Aung N, Sanghvi MM, Zemrak F, Cooper JA, Paiva JM, Thomson RJ, Fung K, Lukaschuk F et al. ( 2017 ) . Age attenuates the relationship between systolic blood pressure and left ventricular mass: evidence from the UK Biobank . EUROPEAN HEART JOURNAL . vol. 38 , 618 - 618 .
Goyal P, Paramesh K, Puranik S ( 2016 ) . Delayed diagnosis of anaphylaxis secondary to ondansetron . European Journal of Anaesthesiology vol. 33 , ( 2 ) 146 - 147 .
Sanghvi MM, Feuchter P, Zemrak F, Boubertakh R, Suinesiaputra A, Young A, Weerackody R, Sekhri N et al. ( 2016 ) . Automatic left ventricular analysis with Inline VF performs well compared to manual analysis: results from Barts Cardiovascular Registry . Journal of Cardiovascular Magnetic Resonance vol. 18 , ( Suppl 1 )
Bansal AS, Sanghvi MM, Bansal RA ( 2014 ) . Variably severe systemic allergic reactions after consuming foods with unlabelled lupin flour: a case series . Journal of Medical Case Reports vol. 8 , ( 1 )
Sanghvi MM, Curtis MRC ( 2013 ) . Allergy Teaching in UK Medical Schools . Journal of Asthma & Allergy Educators vol. 4 , ( 6 ) 266 - 269 .
Zhang M, Brown MR, Bentley AR, Winkler TW, Noordam R, Nagarajan P, Guo B, Lee S et al. . Large-Scale Gene-Smoking Interactions and Fine Mapping Study Identifies Multiple Novel Blood Pressure Loci in over 1 Million Individuals .