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Research

Publications: MR Andrew Smith

Quaye LNK, Dalzell CE, Deloukas P ( 2023 ) . The Genetics of Coronary Artery Disease: A Vascular Perspective . Cells vol. 12 , ( 18 )
Smith AJP, Deloukas P, Munroe PB ( 2018 ) . Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits . Physiological Genomics vol. 50 , ( 7 ) 510 - 522 .
Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J et al. ( 2016 ) . The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals . Nature Genetics vol. 48 , ( 10 ) 1171 - 1184 .
van ’t Hof FNG, Ruigrok YM, Lee CH, Ripke S, Anderson G, de Andrade M, Baas AF, Blankensteijn JD et al. ( 2016 ) . Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms . Journal of the American Heart Association vol. 5 , ( 7 )
Boardman-Pretty F, Smith AJP, Cooper J, Palmen J, Folkersen L, Hamsten A, Catapano AL, Melander O et al. ( 2015 ) . Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant . Circulation Genomic and Precision Medicine vol. 8 , ( 5 ) 696 - 706 .
Boardman-Pretty FA, Smith AJP, Frankel P, Evans IM, Zachary IC, Hamsten A, Gertow K, Humphries SE ( 2014 ) . Functional analysis of the BCAR1-CFDP1-TMEM170A locus associated with carotid intima-media thickness and plaque . Atherosclerosis . vol. 235 ,
Holmes MV, Exeter HJ, Folkersen L, Nelson CP, Guardiola M, Cooper JA, Sofat R, Boekholdt SM et al. ( 2014 ) . Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA2)-V Isoenzyme in Coronary Heart Disease . Circulation Genomic and Precision Medicine vol. 7 , ( 2 ) 144 - 150 .
Bown MJ, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Gretarsdottir S, Badger SA et al. ( 2011 ) . Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1 . American Journal of Human Genetics vol. 89 , ( 5 ) 619 - 627 .
Bown MJ, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Gretarsdottir S, Badger SA et al. ( 2011 ) . Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1 . American Journal of Human Genetics vol. 89 , ( 5 ) 619 - 627 .
Kerkhof HJM, Doherty M, Arden NK, Abramson SB, Attur M, Bos SD, Cooper C, Dennison EM et al. ( 2010 ) . Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis . Osteoarthritis and Cartilage vol. 19 , ( 3 ) 265 - 271 .
Smith AJP, D’Aiuto F, Palmen J, Cooper JA, Samuel J, Thompson S, Sanders J, Donos N et al. ( 2008 ) . Association of Serum Interleukin-6 Concentration with a Functional IL6 −6331T>C Polymorphism . Clinical Chemistry vol. 54 , ( 5 ) 841 - 850 .
( 2004 ) . Extended haplotypes and linkage disequilibrium in the IL1R1–IL1A–IL1B–IL1RN gene cluster: association with knee osteoarthritis . Genes & Immunity vol. 5 , ( 6 ) 451 - 460 .
Haukim N, Bidwell JL, Smith AJP, Keen LJ, Gallagher G, Kimberly R, Huizinga T, McDermott MF et al. ( 2002 ) . Cytokine gene polymorphism in human disease: on-line databases, Supplement 2 . Genes & Immunity vol. 3 , ( 6 ) 313 - 330 .