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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: DR Sara Badodi

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Millner TO, Panday P, Xiao Y, Nicholson J, Boot JR, Arpe Z, Stevens P, Rahman N et al. ( 2025 ) . P09.02.A DISRUPTION OF DNA METHYLATION UNDERPINS THE NEUROINFLAMMATION INDUCED BY TARGETED CNS RADIOTHERAPY . Neuro-Oncology vol. 27 , ( Supplement_3 ) iii89 - iii89 .
Comer C, Cotton K, Edwards C, Dai X, Badodi S, Buccafusca R, Bennett C, Peet A et al. ( 2025 ) . Simvastatin suppresses spinal cord metastasis of medulloblastoma at clinically significant doses . Cell Death & Disease vol. 16 , ( 1 )
Millner TO, Panday P, Xiao Y, Nicholson J, Boot JR, Arpe Z, Stevens PA, Rahman NN et al. ( 2025 ) . Disruption of DNA methylation underpins the neuroinflammation induced by targeted CNS radiotherapy . Brain vol. 148 , ( 9 ) 3137 - 3152 .
Badodi S, Marino S ( 2024 ) . Epigenetic reprogramming enables NF1A/B oncogenic role in SHH medulloblastoma . Developmental Cell vol. 59 , ( 17 ) 2275 - 2276 .
Constantinou M, Nicholson J, Zhang X, Maniati E, Lucchini S, Rosser G, Vinel C, Wang J et al. ( 2024 ) . Lineage specification in glioblastoma is regulated by METTL7B . Cell Reports vol. 43 , ( 6 )
Millner TO, Panday P, Pomella N, Badodi S, Marino S ( 2023 ) . P03.08.A HIGH-DIMENSIONAL CHARACTERISATION OF THE CELLULAR AND MOLECULAR CHANGES IN THE HUMAN BRAIN AFTER RADIOTHERAPY . Neuro-Oncology vol. 25 , ( Supplement_2 ) ii38 - ii38 .
Badodi S, Marino S ( 2023 ) . MDB-16. TARGETING EPIGENETIC DYSREGULATION IN PAEDIATRIC BRAIN TUMOURS . Neuro-Oncology vol. 25 , ( Supplement_1 ) i65 - i65 .
Badodi S, Marino S ( 2023 ) . TARGETING EPIGENETIC DYSREGULATION IN PAEDIATRIC BRAIN TUMOURS . NEURO-ONCOLOGY . vol. 25 ,
Badodi S, Pomella N, Zhang X, Zabet NR, Basson MA, Marino S ( 2022 ) . MEDB-23. Targeting epigenetic dysregulation in medulloblastoma with poor prognosis . Neuro-Oncology vol. 24 , ( Supplement_1 ) i109 - i110 .
Badodi S, Pomella N, Lim YM, Brandner S, Morrison G, Pollard SM, Zhang X, Zabet NR et al. ( 2022 ) . Combination of BMI1 and MAPK/ERK inhibitors is effective in medulloblastoma . Neuro-Oncology vol. 24 , ( 8 ) 1273 - 1285 .
Marino S, Badodi S ( 2022 ) . Epigenetic mechanisms in paediatric brain tumours: regulators lose control . Biochemical Society Transactions
Badodi S, Pomella N, Zhang X, Zabet NR, Basson MA, Marino S ( 2022 ) . TARGETING EPIGENETIC DYSREGULATION IN MEDULLOBLASTOMA WITH POOR PROGNOSIS . NEURO-ONCOLOGY . vol. 24 , 109 - 109 .
Badodi S, Pomella N, Zhang X, Morrison G, Pollard SM, Bennett CD, Clifford SC, Peet A et al. ( 2021 ) . EMBR-10. INOSITOL TREATMENT INHIBITS MEDULLOBLASTOMA THROUGH SUPPRESSION OF EPIGENETIC-DRIVEN METABOLIC ADAPTATION . Neuro-Oncology vol. 23 , ( Supplement_1 ) i7 - i7 .
Ganassi M, Badodi S, Wanders K ( 2020 ) . Myogenin is an essential regulator of adult myofibre growth and muscle stem cell homeostasis . eLife vol. 9 ,
Ricci B, Millner TO, Pomella N, Zhang X, Guglielmi L, Badodi S, Ceric D, Gemma C et al. ( 2020 ) . Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma . Oncogene . vol. 39 , 2523 - 2538 .
Frisira E, Rashid F, Varma SN, Benjamin-Ombo VA ( 2019 ) . NPI-0052 and γ-radiation induce a synergistic apoptotic effect in medulloblastoma . Cell Death & Disease vol. 10 , ( 11 ) Article 785 ,
Badodi S, Marino S, Guglielmi L ( 2018 ) . Establishment and Culture of Patient-Derived Primary Medulloblastoma Cell Lines . Methods in Molecular Biology vol. 1869 , 23 - 36 .
Ganassi M, Badodi S, Zammit PS, Hughes SM ( 2018 ) . Myogenin promotes myocyte fusion to balance fibre number and size . Nature Communications vol. 9 , ( 1 )
MARINO S, BADODI S, Dubuc A, ZHANG X, ROSSER G, Da Cunha Jaeger M, Kameda-Smith M, Morrissy AS et al. ( 2017 ) . Convergence of BMI1 and CHD7 on ERK signalling in medulloblastoma . Cell Reports vol. 21 , ( 10 ) 2772 - 2784 .
Badodi S, Zhang X, Dubuc A, Taylor MD, Marino S ( 2017 ) . MEDU-13. CONVERGENCE OF BMI1 AND CHD7 ON ERK SIGNALLING IN MEDULLOBLASTOMA . Neuro-Oncology vol. 19 , ( suppl_4 ) iv40 - iv40 .
Badodi S, Zhang X, Dubuc A, Taylor MD, Marino S ( 2017 ) . CONVERGENCE OF BMI1 AND CHD7 ON ERK SIGNALLING IN MEDULLOBLASTOMA . NEURO-ONCOLOGY . vol. 19 , 40 - 40 .
Baruffaldi F, Montarras D, Basile V, De Feo L, Badodi S, Ganassi M, Battini R, Imbriano C ( 2016 ) . Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy . Stem Cells vol. 35 , ( 3 ) 725 - 738 .
Badodi S, Ganassi M, Battini R ( 2015 ) . Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition . Cell Cycle vol. 14 , ( 10 ) 1517 - 1528 .
Ganassi M, Badodi S, Polacchini A, Battini R, Hinits Y ( 2014 ) . Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb . Biochimica et Biophysica Acta vol. 1839 , ( 7 ) 559 - 570 .
Marino S, Badodi S . Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation . Nature Communications
Willott T, Nicholson JG, Xiao Y, Ogunbiyi O, Draper B, Mistry T, Donovan L, Zabet NR et al. . Modelling medulloblastoma pathogenesis and treatment in human cerebellar organoids .
Ganassi M, Badodi S, Wanders K, Zammit PS, Hughes SM . Myogenin is an Essential Regulator of Adult Myofibre Growth and Muscle Stem Cell Homeostasis .
Millner T, Panday P, Xiao Y, Boot, Nicholson J, Arpe Z, Stevens P, Rahman N et al. . The inflammatory micro-environment induced by targeted CNS radiotherapy is underpinned by disruption of DNA methylation .
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