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Research

Publications: MISS Sara Maria Caxaria

Hestehave S, Florea R, Singleton S, Fedorec AJH, Caxaria S, Morgan OB, Kopp KT, Brown LA et al. ( 2025 ) . Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms . Proceedings of the National Academy of Sciences of the United States of America vol. 122 , ( 44 )
Haroun R, Gossage SJ, Iseppon F, Fudge A, Caxaria S, Arcangeletti M, Leese C, Davletov B et al. ( 2024 ) . Novel therapies for cancer-induced bone pain . Neurobiology of Pain vol. 16 ,
Bharde S, Caxaria S, Celik P, Srithasan A, Fuller A, Sikandar S ( 2024 ) . 754 Sex Differences in a Murine Model of Osteoarthritis . Osteoarthritis and Cartilage vol. 32 ,
Hong T, Caxaria S, Gatward LFD, King AJF, Rackham CL ( 2023 ) . Mesenchymal stromal cell secretory molecules improve the functional survival of human islets . Diabetic Medicine vol. 40 , ( 12 )
Evans R, Caxaria S, Celik P, Fuller AM, Bharde S, Sikandar S ( 2023 ) . POS0255 A PRO-NOCICEPTIVE POPULATION OF NEUTROPHILS INFILTRATE SENSORY GANGLIA AND MEDIATE CHRONIC WIDESPREAD PAIN IN FIBROMYALGIA SYNDROME .
Bharde S, Caxaria S, Celik P, Sikandar S ( 2023 ) . POS0413 SEX DIFFERENCES IN A MURINE MODEL OF OSTEOARTHRITIS .
Fuller AM, Luiz A, Tian N, Arcangeletti M, Iseppon F, Sexton JE, Millet Q, Caxaria S et al. ( 2023 ) . Gate control of sensory neurotransmission in peripheral ganglia by proprioceptive sensory neurons . Brain vol. 146 , ( 10 ) 4033 - 4039 .
Caxaria S, Bharde S, Fuller AM, Evans R, Thomas B, Celik P, Dell’Accio F, Yona S et al. ( 2023 ) . Neutrophils infiltrate sensory ganglia and mediate chronic widespread pain in fibromyalgia . Proceedings of the National Academy of Sciences of the United States of America vol. 120 , ( 17 )
Caxaria S, Kouvatsos N, Eldridge SE, Alvarez‐Fallas M, Thorup A, Cici D, Barawi A, Arshed A et al. ( 2022 ) . Disease modification and symptom relief in osteoarthritis using a mutated GCP‐2/CXCL6 chemokine . EMBO Molecular Medicine vol. 15 , ( 1 )
Thorup A-S, Wilson J, Strachan D, Caxaria S, Poulet B, Thomas B, Eldridge S, Nalesso G et al. ( 2022 ) . BLOCKING ROR2 IMPROVES CARTILAGE INTEGRITY AND PROVIDES PAIN RELIEF IN OSTEOARTHRITIS, IN PART BY MODULATING YAP SIGNALLING . Osteoarthritis and Cartilage vol. 30 ,
Thorup A-S, Caxaria S, Thomas BL, Suleman Y, Nalesso G, Luyten FP, Dell’Accio F, Eldridge SE ( 2022 ) . In vivo potency assay for the screening of bioactive molecules on cartilage formation . Lab Animal vol. 51 , ( 4 ) 103 - 120 .
Eldridge S, Barawi A, Wang H, Roelofs A, Kaneva M, Guan Z, Lydon H, Thomas B et al. ( 2021 ) . AB0039 AGRIN REPAIRS BONE AND CARTILAGE IN VIVO . Annals of the Rheumatic Diseases vol. 80 ,
Thorup AS, Strachan D, Caxaria S, Poulet B, Thomas B, Eldridge S, Nalesso G, Whiteford J et al. ( 2021 ) . OP0200 BLOCKING ROR2 IMPROVES CARTILAGE INTEGRITY AND PROVIDES PAIN RELIEF IN OSTEOARTHRITIS . Annals of the Rheumatic Diseases vol. 80 , 120 - 121 .
Thomas BL, Eldridge SE, Nosrati B, Alvarez M, Thorup A, Nalesso G, Caxaria S, Barawi A et al. ( 2021 ) . WNT3A‐loaded exosomes enable cartilage repair . Journal of Extracellular Vesicles vol. 10 , ( 7 )
Bharde S, Caxaria S, Dell’Accio F, Sikandar S ( 2021 ) . Update on pain in arthritis . Current Opinion in Supportive and Palliative Care vol. 15 , ( 2 ) 99 - 107 .
Thorup A-S, Strachan D, Caxaria S, Poulet B, Thomas BL, Eldridge SE, Nalesso G, Whiteford JR et al. ( 2020 ) . ROR2 blockade as a therapy for osteoarthritis . Science Translational Medicine vol. 12 , ( 561 )
Eldridge SE, Barawi A, Wang H, Roelofs AJ, Kaneva M, Guan Z, Lydon H, Thomas BL et al. ( 2020 ) . Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis . Science Translational Medicine vol. 12 , ( 559 )
Fallas MA, Caxaria S, Sherwood J, Luyten F, Pitzalis C, Dell'Accio F ( 2018 ) . The role of GCP-2 in cartilage differentiation and repair . Osteoarthritis and Cartilage . vol. 26 ,
Thorup A-S, Eldridge SE, Caxaria S, Nalesso G, Thomas BL, Pitzalis C, Luyten F, Dell'Accio F ( 2017 ) . A Potency Assay for Assessing the Chondrogenic Efficiency of Bioactive Molecules in Human Cartilage in vivo . Osteoarthritis and Cartilage . vol. 25 ,
Eldridge SE, Thomas BL, Shanmuganathan K, Strachan D, Ali A, Thorup A-S, Caxaria S, Nalesso G et al. ( 2017 ) . Agrin inhibits canonical WNT signalling through LRP4 . Osteoarthritis and Cartilage . vol. 25 ,
Caxaria S, Sherwood J, Roeder E, Luyten F, Pitzalis C, Dell'Accio F ( 2017 ) . The Role of CXCl6 in Cartilage Development and Homeostasis . Osteoarthritis and Cartilage . vol. 25 ,
Caxaria S, Arthold S, Nathwani AC ( 2015 ) . Generation of Integration-Free Patient Specific iPS Cells Using Episomal Plasmids Under Feeder Free Conditions . Patient-Specific Induced Pluripotent Stem Cell Models , vol. 1353 , Springer Nature
( 2013 ) . A Systematic Evaluation of Integration Free Reprogramming Methods for Deriving Clinically Relevant Patient Specific Induced Pluripotent Stem (iPS) Cells . PLOS ONE vol. 8 , ( 11 )
Hestehave S, Florea R, Singleton S, Fedorec AJH, Caxaria S, Morgan O, Kopp KT, Brown LA et al. . Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms .
Caxaria S, Bharde S, Fuller AM, Evans R, Thomas B, Celik P, Dell’Accio F, Yona S et al. . Neutrophils infiltrate sensory ganglia and mediate chronic widespread pain in fibromyalgia .
Haroun R, Gossage SJ, Iseppon F, Fudge A, Caxaria S, Arcangeletti M, Leese C, Davletov B et al. . Novel therapies for cancer-induced bone pain .
Esfahani SJ, Oveisi A, Lima LV, Caxaria S, Parisien M, Vignone J, Montagna F, Sikandar S et al. . Paradoxical Phenotype of Fibromyalgia Neutrophils with Elevated Baseline Inflammation but Blunted Response to Stimulation .