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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: DR Joseph Gibbons

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( 2025 ) . Temporary 2-week suspension of methotrexate treatment to enhance COVID-19 vaccine response in people with immune-mediated inflammatory diseases: the VROOM RCT . Efficacy and Mechanism Evaluation1 - 42 .
( 2025 ) . Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial . Efficacy and Mechanism Evaluation vol. 12 , ( 05 ) 47 - 48 .
( 2025 ) . Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial . Efficacy and Mechanism Evaluation vol. 12 , ( 05 ) 45 - 46 .
( 2025 ) . Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study) . Efficacy and Mechanism Evaluation vol. 12 , ( 05 ) 43 - 44 .
( 2024 ) . Influence of individuals’ determinants including vaccine type on cellular and humoral responses to SARS-CoV-2 vaccination . npj Vaccines vol. 9 , ( 1 ) Article 87 ,
( 2024 ) . Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1 .
( 2024 ) . Effect of a 2-week interruption in methotrexate treatment on COVID-19 vaccine response in people with immune-mediated inflammatory diseases (VROOM study): a randomised, open label, superiority trial . The Lancet Rheumatology vol. 6 , ( 2 ) e92 - e104 .
Miyashita L, Foley G, Semple S, Gibbons JM, Pade C, McKnight Á, Grigg J ( 2023 ) . Curbside particulate matter and susceptibility to SARS–CoV-2 infection . Journal of Allergy and Clinical Immunology: Global vol. 2 , ( 4 ) Article 100141 , 100141 - 100141 .
Gokani B, Sacoor S, Leisegang GR, Ogunkolade W, Bibi A, Grigoriadou S, Pade C, Gibbons J et al. ( 2023 ) . Behçet's patients' response to COVID-19 vaccination . Clinical Immunology vol. 255 , Article 109700 , 109700 - 109700 .
( 2023 ) . Influence of age, sex, body habitus, vaccine type and anti-S serostatus on cellular and humoral responses to SARS-CoV-2 vaccination .
( 2023 ) . Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity . Nature Communications vol. 14 , ( 1 ) Article 5139 ,
Milojkovic D, Reynolds CJ, Sandoval DM, Pieper FP, Liu S, Pade C, Gibbons JM, McKnight Á et al. ( 2022 ) . COVID-19 vaccine boosted immunity against Omicron in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors . Leukemia vol. 37 , ( 1 ) 244 - 247 .
( 2022 ) . Persistent symptoms after COVID-19 during the first wave are not associated with differential immunity to SARS-CoV-2 .
( 2022 ) . Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection .
( 2022 ) . Plasma proteomic signature predicts who will get persistent symptoms following SARS-CoV-2 infection . eBioMedicine vol. 85 , Article 104293 , 104293 - 104293 .
( 2022 ) . Vitamin D Supplementation Does Not Influence SARS-CoV-2 Vaccine Efficacy or Immunogenicity: Sub-Studies Nested within the CORONAVIT Randomised Controlled Trial . Nutrients vol. 14 , ( 18 ) 3821 - 3821 .
( 2022 ) . Quantitative, multiplexed, targeted proteomics for ascertaining variant specific SARS-CoV-2 antibody response . Cell Reports Methods vol. 2 , ( 9 ) Article 100279 , 100279 - 100279 .
( 2022 ) . Correlation Between Postvaccination Anti-Spike Antibody Titers and Protection Against Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Population-Based Longitudinal Study . The Journal of Infectious Diseases vol. 226 , ( 11 ) 1903 - 1908 .
( 2022 ) . Influence of vitamin D supplementation on SARS-CoV-2 vaccine efficacy and immunogenicity .
( 2022 ) . Immune boosting by B.1.1.529\n <b>(</b>\n Omicron) depends on previous SARS-CoV-2 exposure . Science vol. 377 , ( 6603 ) Article eabq1841 ,
Riddell AC, Kele B, Harris K, Bible J, Murphy M, Dakshina S, Storey N, Owoyemi D et al. ( 2022 ) . Generation of Novel Severe Acute Respiratory Syndrome Coronavirus 2 Variants on the B.1.1.7 Lineage in 3 Patients With Advanced Human Immunodeficiency Virus-1 Disease . Clinical Infectious Diseases vol. 75 , ( 11 ) 2016 - 2018 .
( 2022 ) . HLA‐DR polymorphism in SARS‐CoV‐2 infection and susceptibility to symptomatic COVID‐19 . Immunology vol. 166 , ( 1 ) 68 - 77 .
( 2022 ) . Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections . Cell Reports Medicine vol. 3 , ( 3 ) Article 100557 , 100557 - 100557 .
( 2022 ) . Quantitative, multiplexed, targeted proteomics for ascertaining variant specific SARS-CoV-2 antibody response .
( 2022 ) . Correlation between post-vaccination titres of combined IgG, IgA, and IgM anti-Spike antibodies and protection against breakthrough SARS-CoV-2 infection: a population-based longitudinal study (COVIDENCE UK) .
( 2022 ) . Generation of novel SARS-CoV-2 variants on B.1.1.7 lineage in three patients with advanced HIV disease .
( 2022 ) . Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants . Science vol. 375 , ( 6577 ) 183 - 192 .
( 2022 ) . The β-NGF/TrkA Signalling Pathway Is Associated With the Production of Anti-Nucleoprotein IgG in Convalescent COVID-19 . Frontiers in Immunology vol. 12 , Article 813300 ,
( 2021 ) . The β-NGF/TrkA signalling pathway is associated with the production of anti- nucleoprotein IgG in convalescent COVID-19 .
( 2021 ) . Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 . Nature vol. 601 , ( 7891 ) 110 - 117 .
( 2021 ) . Prospective Case-Control Study of Cardiovascular Abnormalities 6 Months Following Mild COVID-19 in Healthcare Workers . JACC: Cardiovascular Imaging vol. 14 , ( 11 ) 2155 - 2166 .
( 2021 ) . Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study . The Lancet Microbe vol. 2 , ( 10 ) e508 - e517 .
( 2021 ) . Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 infection .
( 2021 ) . Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose . Science vol. 372 , ( 6549 ) 1418 - 1423 .
( 2021 ) . Non-severe SARS-CoV-2 infection is characterised by very early T cell proliferation independent of type 1 interferon responses and distinct from other acute respiratory viruses .
( 2021 ) . Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection . EBioMedicine vol. 65 , Article 103259 , 103259 - 103259 .
( 2020 ) . Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection . Science Immunology vol. 5 , ( 54 ) Article eabf3698 ,
( 2020 ) . Characterising heterogeneity and sero-reversion in antibody responses to mild SARS⍰CoV-2 infection: a cohort study using time series analysis and mechanistic modelling .
( 2020 ) . Healthcare workers with mild / asymptomatic SARS-CoV-2 infection show T cell responses and neutralising antibodies after the first wave .
( 2020 ) . Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19 . Wellcome Open Research vol. 5 , 179 - 179 .
( 2020 ) . Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19 . Wellcome Open Research vol. 5 , 179 - 179 .
( 2020 ) . HIV-1 Accessory Protein Vpr Interacts with REAF/RPRD2 To Mitigate Its Antiviral Activity . Journal of Virology vol. 94 , ( 4 ) Article e01591-19 ,
( 2019 ) . HIV-1 Vpr accessory protein interacts with REAF and mitigates its associated anti-viral activity . Access Microbiology vol. 1 , ( 1A )
( 2019 ) . HIV-1 infectivity of cells is enhanced at mitosis: a role for Vpr? . Access Microbiology vol. 1 , ( 1A )
( 2018 ) . HIV-1 accessory protein Vpr interacts with REAF/RPRD2 to mitigate its antiviral activity .
Miyashita L, Foley G, Semple S, Gibbons J, Pade C, Mcknight A, Grigg J . Kerbside Particulate Matter and Susceptibility to SARS-CoV-2 Infection .
. Large Clones of Pre-Existing T Cells Drive Early Immunity Against SARS-COV-2 and LCMV Infection .
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