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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: DR Wing-Yiu Lee

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Lee W-YJ, Foster GR ( 2023 ) . Hepatitis C . Encyclopedia of Cell Biology , Elsevier
( 2022 ) . Quantitative, multiplexed, targeted proteomics for ascertaining variant specific SARS-CoV-2 antibody response . Cell Reports Methods vol. 2 , ( 9 )
( 2022 ) . Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure . Science vol. 377 , ( 6603 )
( 2022 ) . HLA‐DR polymorphism in SARS‐CoV‐2 infection and susceptibility to symptomatic COVID‐19 . Immunology vol. 166 , ( 1 ) 68 - 77 .
( 2022 ) . The cation channel TRPM8 influences the differentiation and function of human monocytes . Journal of Leukocyte Biology vol. 112 , ( 3 ) 365 - 381 .
( 2021 ) . Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 . Nature
( 2021 ) . Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study . Lancet Microbe vol. 2 , ( 10 ) e508 - e517 .
( 2021 ) . Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses . Frontiers in Immunology vol. 12 ,
( 2021 ) . Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose . Science vol. 372 , ( 6549 ) 1418 - 1423 .
( 2020 ) . Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence .
( 2020 ) . Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection . Science Immunology vol. 5 , ( 54 )
( 2020 ) . Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures . Frontiers in Immunology vol. 11 ,
Jason Lee W-Y, Jones M, Wing PAC, Rajagopal S, Foster GR ( 2020 ) . The A150V polymorphism of genotype 3 hepatitis C virus polymerase inhibits interferon alfa by suppressing protein kinase R activation . Cellular and Molecular Gastroenterology and Hepatology
( 2020 ) . Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19 . Wellcome Open Research vol. 5 , 179 - 179 .
Lee W-YJ, Jones M, Wing PA, Rajagopal S, Foster GR ( 2020 ) . O4 Amino acid substitution in genotype 3a hepatitis C virus polymerase protein affects responses to sofosbuvir and interferon alpha and inhibits apoptosis . Gut vol. 69 , ( Suppl 1 ) a2 - a3 .
( 2020 ) . Deep sequencing of B cell receptor repertoires from COVID-19 patients reveals strong convergent immune signatures .
( 2020 ) . HIV-1 Accessory Protein Vpr Interacts with REAF/RPRD2 To Mitigate Its Antiviral Activity . Journal of Virology vol. 94 , ( 4 ) 10.1128/jvi.01591 - 10.1128/jvi.01519 .
Wing PAC, Jones M, Cheung M, DaSilva S, Bamford C, Lee W-YJ, Aranday-Cortes E, Da Silva Filipe A et al. ( 2019 ) . Amino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sofosbuvir . Gastroenterology vol. 157 , ( 3 ) 692 - 704.e9 .
( 2019 ) . HIV-1 infectivity of cells is enhanced at mitosis: a role for Vpr? . Access Microbiology vol. 1 , ( 1A )
( 2019 ) . Simultaneous polychromatic flow cytometric detection of multiple forms of regulated cell death . Apoptosis
LEE WJ, Fu RM, Liang C, SLOAN RD ( 2018 ) . IFITM proteins inhibit HIV-1 protein synthesis . Scientific Reports
Foster GR, Wing P, Jones M, Lee W-YJ, Cheung MC, McLauchlan J, daSilva-Filipe A, Irving W et al. ( 2017 ) . Polymorphisms in the genotype 3 hepatitis C virus polymerase protein modify the response to interferon and sofosbuvir . HEPATOLOGY . vol. 66 , 1270A - 1270A .
Zurnic I, Hütter S, Lehmann U, Stanke N, Reh J, Kern T, Lindel F, Gerresheim G et al. ( 2016 ) . Proceedings of the Frontiers of Retrovirology Conference 2016 . Retrovirology vol. 13 , ( Suppl 1 )
Lee W-Y, Tolar P ( 2013 ) . Activation of the B cell receptor leads to increased membrane proximity of the Igα cytoplasmic domain . PLoS One vol. 8 , ( 11 ) e79148 - e79148 .
Natkanski E, Lee W-Y, Mistry B, Casal A, Molloy JE, Tolar P ( 2013 ) . B Cells Use Mechanical Energy to Discriminate Antigen Affinities . Science vol. 340 , ( 6140 ) 1587 - 1590 .
Lee W-Y, Hampson P, Coulthard L, Ali F, Salmon M, Lord JM, Scheel-Toellner D ( 2010 ) . Novel Antileukemic Compound Ingenol 3-Angelate Inhibits T Cell Apoptosis by Activating Protein Kinase Cθ* . Journal of Biological Chemistry vol. 285 , ( 31 ) 23889 - 23898 .
Biswas D, Qureshi OS, Lee W-Y, Croudace JE, Mura M, Lammas DA ( 2008 ) . ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages . BMC Immunology vol. 9 , ( 1 )
Scheel-Toellner D, Raza K, Assi L, Pilling D, Ross EJ, Lee WY, Curnow SJ, Buckley CD et al. ( 2007 ) . Differential regulation of nuclear and mitochondrial Bcl-2 in T cell apoptosis . Apoptosis vol. 13 , ( 1 ) 109 - 117 .
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