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Research

Publications: P Kunal Shah

Shah KM, Crozier AFF, Assaraf A, Arya M, Grevitt P, Mardakheh F, Plevin MJ, Sharp TV ( 2025 ) . C-terminal tagging impairs AGO2 function . RNA Biology vol. 22 , ( 1 ) 1 - 24 .
Grevitt P, Maiques O, Shah KM, Morales V, Gadaleta E, Dodel M, Bianchi K, Gout I et al. ( 2025 ) . Coenzyme A homeostasis regulates hypoxic signalling via UBFD1 in triple-negative breast cancer .
Saha A, Grevitt P, Junior JM, Von Kriegsheim A, Shah K, Gao Z, Stockwell BR, Finch A et al. ( 2025 ) . LIMD1 Loss Confers a GPX4-Dependent Cell State in Lung Cancer .
Sharp T, Shah K, Kennedy P, Black J, Litchfield K, Thakkar K, KBrooksbank K, Yuan O et al. ( 2025 ) . LIMD1 Loss as an Early Driver of PD-L1 Upregulation and Immune Evasion in Lung Cancer .
Shah KM, Kennedy PT, Black JRM, Litchfield K, Thakkar K, Contreras-Gerenas MF, Brooksbank K, Yuan O et al. ( 2025 ) . LIMD1 Loss as an Early Driver of PD-L1 Upregulation and Immune Evasion in Lung Cancer .
Weeks S, Pezic D, Dodel M, Shah K, Bhamra A, Henderson S, Surinova S, Sharp T et al. ( 2024 ) . STAG3 promotes exit from pluripotency through post-transcriptional mRNA regulation in the cytoplasm .
Shah KM, Crozier AFF, Assaraf AA, Arya M, Grevitt P, Mardakheh F, Plevin MJ, Sharp TV ( 2023 ) . C-terminal tagging impairs AGO2 function .
Hallberg M, Morganstein DL, Kiskinis E, Shah K, Kralli A, Dilworth SM, White R, Parker MG et al. ( 2023 ) . A Functional Interaction between RIP140 and PGC-1α Regulates the Expression of the Lipid Droplet Protein CIDEA . Molecular and Cellular Biology vol. 28 , ( 22 ) 6785 - 6795 .
Davidson K, Grevitt P, Contreras-Gerenas MF, Bridge KS, Hermida M, Shah KM, Mardakheh FK, Stubbs M et al. ( 2021 ) . Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes . Cell Death & Disease vol. 12 , ( 11 ) Article 1075 ,
Davidson K, Grevitt P, Contreras G. MF, Bridge KS, Hermida M, Shah KM, Mardakheh FK, Stubbs M et al. ( 2021 ) . Targeted therapy for<i>LIMD1</i>-deficient non-small cell lung cancer subtypes .
Hewitson JP, Shah KM, Brown N, Grevitt P, Hain S, Newling K, Sharp TV, Kaye PM et al. ( 2019 ) . miR‐132 suppresses transcription of ribosomal proteins to promote protective Th1 immunity . EMBO reports vol. 20 , ( 4 ) Article e46620 ,
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A et al. ( 2018 ) . A\n <scp>HIF</scp>\n –\n <scp>LIMD</scp>\n 1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia . EMBO Molecular Medicine vol. 10 , ( 8 ) Article e8304 ,
Yee D, Shah KM, Coles MC, Sharp TV, Lagos D ( 2017 ) . MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells . Journal of Biological Chemistry vol. 292 , ( 50 ) 20683 - 20693 .
Bridge KS, Shah KM, Li Y, Foxler DE, Wong SCK, Miller DC, Davidson KM, Foster JG et al. ( 2017 ) . Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins . Cell Reports vol. 20 , ( 1 ) 173 - 187 .
Feber A, Worth DC, Chakravarthy A, de Winter P, Shah K, Arya M, Saqib M, Nigam R et al. ( 2016 ) . <i>CSN1</i> Somatic Mutations in Penile Squamous Cell Carcinoma . Cancer Research vol. 76 , ( 16 ) 4720 - 4727 .
Leonov G, Shah K, Yee D, Timmis J, Sharp TV, Lagos D ( 2015 ) . Suppression of AGO2 by miR-132 as a determinant of miRNA-mediated silencing in human primary endothelial cells . The International Journal of Biochemistry &amp; Cell Biology vol. 69 , 75 - 84 .
Shah KM, Webber J, Carzaniga R, Taylor DM, Fusi L, Clayton A, Brosens JJ, Hartshorne G et al. ( 2012 ) . Induction of microRNA resistance and secretion in differentiating human endometrial stromal cells . Journal of Molecular Cell Biology vol. 5 , ( 1 ) 67 - 70 .
Lam EW-F, Shah K, Brosens JJ ( 2012 ) . The diversity of sex steroid action: the role of micro-RNAs and FOXO transcription factors in cycling endometrium and cancer . Journal of Endocrinology vol. 212 , ( 1 ) 13 - 25 .
Cloke B, Shah K, Kaneda H, Lavery S, Trew G, Fusi L, Higham J, Dina RE et al. ( 2010 ) . The Poly(C)-Binding Protein-1 Regulates Expression of the Androgen Receptor . Endocrinology vol. 151 , ( 8 ) 3954 - 3964 .