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Research

Publications: Dr Alison Thomas

Tsisanova E, Nobles M, Sebastian S, Ng K-E, Thomas A, Weinstein LS, Munroe PB, Tinker A ( 2024 ) . The ric-8b protein (resistance to inhibitors of cholinesterase 8b) is key to preserving contractile function in the adult heart . Journal of Biological Chemistry vol. 300 , ( 7 )
Rodriguez A, Villar D, Frost S, Tinker A, Thomas A ( 2023 ) . BS56 An epigenomic investigation of atrial fibrillation in a paired left and right atrial cohort . Conference: Basic Sciencea285.1 - a2a285 .
Thomas AM, Cabrera CP, Finlay M, Lall K, Nobles M, Schilling RJ, Wood K, Mein CA et al. ( 2019 ) . Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages . Physiol Genomics vol. 51 , ( 8 ) 323 - 332 .
Aziz Q, Thomas AM, Gomes J, Ang R, Sones WR, Li Y, Ng K-E, Gee L et al. ( 2014 ) . The ATP-Sensitive Potassium Channel Subunit, Kir6.1, in Vascular Smooth Muscle Plays a Major Role in Blood Pressure Control . Hypertension vol. 64 , ( 3 ) 523 - 529 .
Tinker A, Aziz Q, Thomas A ( 2014 ) . The role of ATP-sensitive potassium channels in cellular function and protection in the cardiovascular system . Br J Pharmacol vol. 171 , ( 1 ) 12 - 23 .
Telezhkin V, Thomas AM, Harmer SC, Tinker A, Brown DA ( 2013 ) . A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P2 . Pflügers Archiv - European Journal of Physiology vol. 465 , ( 7 ) 945 - 953 .
Thomas AM, Harmer SC, Khambra T, Tinker A ( 2011 ) . Characterization of a binding site for anionic phospholipids on KCNQ1 . Journal of Biological Chemistry vol. 286 , 2088 - 2100 .
Orie N, Thomas A, Perrino B, Tinker A, Clapp L ( 2009 ) . Ca2+/calcineurin regulation of cloned vascular KATP channels: crosstalk with the protein kinase A pathway . British Journal of Pharmacology vol. 157 , ( 4 ) 554 - 564 .
Muzyamba M, Farzaneh T, Behe P, Thomas A, Christesen HBT, Brusgaard K, Hussain K, Tinker A ( 2007 ) . Complex ABCC8 DNA variations in congenital hyperinsulinism: lessons from functional studies . Clinical Endocrinology vol. 67 , ( 1 ) 115 - 124 .