Publications: DR Amie Moyes

Lowe VJ, Aubdool AA, Moyes AJ, Dignam JP, Perez-Ternero C, Baliga RS, Smart N, Hobbs AJ ( 2024 ) . Cardiomyocyte-derived C-type natriuretic peptide diminishes myocardial ischaemic injury by promoting revascularisation and limiting fibrotic burden . Pharmacological Research vol. 209 , Article 107447 , 107447 - 107447 .

Dickinson YA, Moyes AJ, Hobbs AJ ( 2024 ) . C-type natriuretic peptide (CNP): The cardiovascular system and beyond . Pharmacology & Therapeutics vol. 262 , Article 108708 , 108708 - 108708 .

Aubdool AA, Moyes AJ, Perez-Ternero C, Tsui JC, Lu HS, Daugherty A, Hobbs AJ ( 2023 ) . Abstract 15171: Endothelium-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Abdominal Aortic Aneurysm . Circulation vol. 148 , ( Suppl_1 )

Moyes A, Sand C, Aubdool A, Perez-Ternero C, Mohammad S, Thiemermann C, Hobbs A ( 2023 ) . C-type Natriuretic Peptide Attenuates Endothelial and Cardiac Dysfunction During Endotoxemia and Polymicrobial Sepsis . B45. NEW STUDIES IN SEPSIS AND INFECTIOUS DISEASES . Conference: American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DCA3433 - A3433 .

Perez-Ternero C, Aubdool A, Makwana R, Sanger G, Stimson R, Chan L, Moyes A, Hobbs A ( 2023 ) . C-type natriuretic peptide regulates metabolic homeostasis . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,

Perez-Ternero C, Aubdool A, Makwana R, Sanger G, Stimson R, Chan L, Moyes A, Hobbs A ( 2023 ) . C-type natriuretic peptide regulates metabolic homeostasis . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,

Perez-Ternero C, Aubdool AA, Makwana R, Sanger GJ, Stimson RH, Chan LF, Moyes AJ, Hobbs AJ ( 2022 ) . C-type natriuretic peptide is a pivotal regulator of metabolic homeostasis . Proceedings of the National Academy of Sciences vol. 119 , ( 13 ) Article e2116470119 ,

Grange RMH, Preedy MEJ, Renukanthan A, Dignam JP, Lowe VJ, Moyes AJ, Pérez‐Ternero C, Aubdool AA et al. ( 2021 ) . Multidrug resistance proteins preferentially regulate natriuretic peptide‐driven cGMP signalling in the heart and vasculature . British Journal of Pharmacology vol. 179 , ( 11 ) 2443 - 2459 .

Aziz Q, Chen J, Moyes AJ, Li Y, Anderson NA, Ang R, Aksentijevic D, Sebastian S et al. ( 2020 ) . Vascular KATP channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia . Journal of Molecular Medicine vol. 98 , ( 8 ) 1149 - 1160 .

Moyes AJ, Hobbs AJ ( 2019 ) . C-Type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature . International Journal of Molecular Sciences vol. 20 , ( 9 ) 2281 - 2281 .

Hobbs AJ, Moyes AJ, Baliga RS, Ghedia D, Ochiel R, Sylvestre Y, Doré CJ, Chowdhury K et al. ( 2019 ) . Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double‐blind, placebo‐controlled, proof‐of‐concept trial . British Journal of Pharmacology vol. 176 , ( 9 ) 1251 - 1267 .

Bubb KJ, Aubdool AA, Moyes AJ, Lewis S, Drayton JP, Tang O, Mehta V, Zachary IC et al. ( 2019 ) . Endothelial C-Type Natriuretic Peptide Is a Critical Regulator of Angiogenesis and Vascular Remodeling . Circulation vol. 139 , ( 13 ) 1612 - 1628 .

Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS et al. ( 2019 ) . C-type natriuretic peptide co-ordinates cardiac structure and function . European Heart Journal vol. 41 , ( 9 ) 1006 - 1020 .

Perez-Ternero C, Aubdool AA, Moyes AJ, Hobbs AJ ( 2019 ) . C-Type Natriuretic Peptide (CNP) Regulates Adipogenesis, Thermogenesis and Glucose Sensitivity via Natriuretic Peptide Receptor (NPR)-C Signalling . CIRCULATION . vol. 140 ,

Preedy ME, Baliga RS, Dukinfield MS, Chu SM, Aubdool AA, Bubb KJ, Moyes AJ, Tones MA et al. ( 2019 ) . Inhibition of phosphodiesterase 2 reverses the development of heart failure by promoting NO/guanylyl cyclase/cGMP signalling . BRITISH JOURNAL OF PHARMACOLOGY . vol. 176 , 3008 - 3009 .

Preedy MEJ, Baliga R, Dukinfield M, Chu S, Aubdool A, Bubb K, Moyes A, Tones M et al. ( 2019 ) . Phosphodiesterase 2 promotes nitric oxide/guanylyl cyclase/cGMP signalling in heart failure . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 17 ,

Baliga RS, Preedy MEJ, Dukinfield MS, Chu SM, Aubdool AA, Bubb KJ, Moyes AJ, Tones MA et al. ( 2018 ) . Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure . Proceedings of the National Academy of Sciences vol. 115 , ( 31 )

Todd Milne G, Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS et al. ( 2017 ) . Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications . BMC Pharmacology and Toxicology vol. 18 , ( S1 ) Article 64 ,

Aubdool AA, Bubb KJ, Moyes AJ, Drayton JP, Mehta V, Zachary IC, Tsui J, Abraham DJ et al. ( 2017 ) . Endothelium-Derived C-Type Natriuretic Peptide is a Critical Regulator of Angiogenesis and Vascular Remodelling . CIRCULATION . vol. 136 ,

Villar IC, Bubb KJ, Moyes AJ, Steiness E, Gulbrandsen T, Levy FO, Hobbs AJ ( 2016 ) . Functional pharmacological characterization of SER100 in cardiovascular health and disease . British Journal of Pharmacology vol. 173 , ( 23 ) 3386 - 3401 .

( 2016 ) . IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD . Journal of the American Society of Nephrology vol. 28 , ( 1 ) 94 - 105 .

Moyes AJ, Stanford SC, Hosford PS, Hobbs AJ, Ramage AG ( 2016 ) . Raised arterial blood pressure in neurokinin‐1 receptor‐deficient mice (<i>NK1R</i>^−/−): evidence for a neural rather than a vascular mechanism . Experimental Physiology vol. 101 , ( 5 ) 588 - 598 .

Baliga RS, Moyes AJ, Villar IC, Schaeper U, Iannone L, Hobbs AJ ( 2016 ) . Therapeutic Proof-Of-Concept For Novel Sirna Technology In Experimental Pulmonary Hypertension . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 193 ,

Moyes AJ, Chu SM, Baliga RS, Hobbs AJ ( 2015 ) . Abstract 19478: Endothelial and Cardiomyocyte -derived C-type Natriuretic Peptide Coordinate Heart Structure and Function . Circulation vol. 132 , ( suppl_3 )

Allen RMH, Renukanthan A, Bubb KJ, Villar IC, Moyes AJ, Baliga RS, Hobbs AJ ( 2015 ) . Investigation of the role of multidrug resistance proteins (MRPs) in vascular homeostasis . BMC Pharmacology and Toxicology vol. 16 , ( S1 ) Article A33 ,

Allen R, Renukanthan A, Bubb K, Villar I, Moyes A, Baliga R, Hobbs A ( 2015 ) . Investigation of the Role of Multidrug Resistance Proteins (MRPs) in Vascular Homeostasis . The FASEB Journal vol. 29 , ( S1 )

Moyes AJ, Chu SM, Baliga RS, Hobbs AJ ( 2015 ) . Endothelial and Cardiomyocyte-derived C-type Natriuretic Peptide Coordinate Heart Structure and Function . CIRCULATION . vol. 132 ,

Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ et al. ( 2014 ) . Endothelial C-type natriuretic peptide maintains vascular homeostasis . Journal of Clinical Investigation vol. 124 , ( 9 ) 4039 - 4051 .

Gonzales MA, Han H, Moyes A, Radinos A, Hobbs AJ, Coombs N, Oliver SRJ, Mascharak PK ( 2014 ) . Light-triggered carbon monoxide delivery with Al-MCM-41-based nanoparticles bearing a designed manganese carbonyl complex . Journal of Materials Chemistry B vol. 2 , ( 15 ) 2107 - 2107 .

Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ, Hobbs AJ et al. ( 2014 ) . Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo model . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 95 , A27 - A27 .

Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ, Hobbs AJ et al. ( 2013 ) . Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model . Arthritis Research &amp; Therapy vol. 15 , ( 4 ) Article R76 ,

Sciarretta S, Marchitti S, Bianchi F, Moyes A, Barbato E, Di Castro S, Stanzione R, Cotugno M et al. ( 2013 ) . C2238 Atrial Natriuretic Peptide Molecular Variant Is Associated With Endothelial Damage and Dysfunction Through Natriuretic Peptide Receptor C Signaling . Circulation Research vol. 112 , ( 10 ) 1355 - 1364 .

Moyes AJ, Khambata RS, Ahluwalia A, Hobbs AJ ( 2012 ) . Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide . CIRCULATION vol. 126 , ( 21 )

Gonzalez MA, Yim MA, Cheng S, Moyes A, Hobbs AJ, Mascharak PK ( 2011 ) . Manganese Carbonyls Bearing Tripodal Polypyridine Ligands as Photoactive Carbon Monoxide-Releasing Molecules . Inorganic Chemistry vol. 51 , ( 1 ) 601 - 608 .

. Endogenous C-type natriuretic peptide mitigates vascular dysfunction, inflammation and cardiomyopathy during endotoxemia and polymicrobial sepsis . Endogenous C-type natriuretic peptide mitigates vascular dysfunction, inflammation and cardiomyopathy during endotoxemia and polymicrobial sepsis . Conference: cGMP: Generators, Effectors and Therapeutic Implications