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  1. Queen Mary University of London
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Publications: MRS Charlotte Ackerman

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Aziz NA, Ng K, Alifrangis C, Tran B, Conduit C, Liow E, Ackerman C, Georgescu R et al. ( 2025 ) . Therapy de‐escalation for testicular cancer (THERATEST): A multi‐centre observational cohort feasibility study of de‐escalation therapies for good prognosis stage II germ cell tumours . BJUI Compass vol. 6 , ( 8 ) Article e70057 ,
Jackson-Spence F, Larkin J, Patel P, Valderrama BP, Rodriguez-Vida A, Mendez-Vidal MJ, Childress M, Li W et al. ( 2025 ) . Final overall survival and new ctDNA analysis in MET-driven advanced papillary renal cancer (CALYPSO) . Journal of Clinical Oncology vol. 43 , ( 5_suppl ) 444 - 444 .
Abdul Aziz N, Ng K, Alifrangis C, Tran B, Conduit C, Liow ECH, Ackerman C, Georgescu R et al. ( 2025 ) . THERATEST: A multi-centre observational cohort feasibility study of de-escalation therapies for stage II seminoma . Journal of Clinical Oncology vol. 43 , ( 5_suppl )
Kocher HM, Ackermann C, Priyadarshini G, Lawrence C, Kotriwala N, Georgescu R, Roberts R, Hughes C et al. ( 2025 ) . Study protocol: multi-centre, randomised controlled clinical trial exploring stromal targeting in locally advanced pancreatic cancer; STARPAC2 . BMC Cancer vol. 25 , ( 1 ) Article 106 ,
Jackson-Spence F, Ackerman C, Jones R, Toms C, Jovaisaite A, Young M, Hussain S, Protheroe A et al. ( 2024 ) . Biomarkers associated with survival in patients with platinum-refractory urothelial carcinoma treated with paclitaxel . Urologic Oncology: Seminars and Original Investigations vol. 42 , ( 11 ) 372.e1 - 372.e10 .
Jackson-Spence F, Rodriguez CS, Larkin J, Patel P, Valderrama BP, Rodriguez-Vida A, Mendez Vidal MJ, Markovets A et al. ( 2023 ) . 1888P 24-month follow up of durvalumab and savolitinib combination in MET-driven clear cell and non-clear cell renal cancer . Annals of Oncology vol. 34 , S1016 - S1016 .
Tan WS, Prendergast A, Ackerman C, Yogeswaran Y, Cresswell J, Mariappan P, Phull J, Hunter-Campbell P et al. ( 2023 ) . Adjuvant Intravesical Chemohyperthermia Versus Passive Chemotherapy in Patients with Intermediate-risk Non–muscle-invasive Bladder Cancer (HIVEC-II): A Phase 2, Open-label, Randomised Controlled Trial . European Urology vol. 83 , ( 6 ) 497 - 504 .
Jackson-Spence F, Ackerman C, Szabados B, Toms C, Jovaisaite A, Gunnell R, Suárez C, Larkin J et al. ( 2023 ) . DNA alterations in papillary renal cancer . Journal of Clinical Oncology vol. 41 , ( 6_suppl ) 725 - 725 .
Jackson-Spence FE, Powles T, Loriot Y, Toms C, Jovaisaite A, Choy J, Szabados BE, Nudds H et al. ( 2022 ) . Trial In Progress: DISCUS: A randomized phase II study comparing 3 vs. 6 cycles of platinum-based chemotherapy prior to maintenance avelumab in advanced urothelial cancer . European Urology Open Science vol. 45 , S219 - S219 .
Szabados B, Duncan S, Choy J, Jackson-Spence F, Toms C, Trevisan G, Berney DM, Powles T et al. ( 2022 ) . Androgen Receptor Expression Is a Predictor of Poor Outcome in Urothelial Carcinoma . Frontiers in Urology vol. 2 , Article 863784 ,
Schmid P, Gomez-Pardo P, Wheatley D, Roy P, Krabisch P, Thill M, Ledwidge S, Thompson A et al. ( 2021 ) . 208P ARB: Phase II window of opportunity study of preoperative treatment with enzalutamide in ER+ve and TNBC . Annals of Oncology vol. 32 , S449 - S450 .
Jackson-Spence FE, Ackerman C, Khan M, Grant M, Soosaipillai G, Nally E, Choy J, Powles TB et al. ( 2021 ) . The role of angiogenic signatures in advanced urothelial carcinoma (aUC) treated with VEGF-targeted therapy . European Urology vol. 79 , S636 - S636 .
Hall PE, Shepherd STC, Brown J, Larkin J, Jones R, Ralph C, Hawkins R, Chowdhury S et al. ( 2020 ) . Radiological Response Heterogeneity Is of Prognostic Significance in Metastatic Renal Cell Carcinoma Treated with Vascular Endothelial Growth Factor-targeted Therapy . European Urology Focus vol. 6 , ( 5 ) 999 - 1005 .
Powles T, Gómez de Liaño A, Ackerman C ( 2017 ) . Reply to Pontus Eriksson, Gottfrid Sjödahl, and Fredrik Liedberg's Letter to the Editor re: Thomas Powles, Robert A. Huddart, Tony Elliott, et al. Phase III, Double-blind, Randomized Trial that Compared Maintenance Lapatinib versus Placebo after First-line Chemotherapy in Patients with Human Epidermal Growth Factor Receptor 1/2-positive Metastatic Bladder Cancer. J Clin Oncol 2017;35:48–55. Knowing HER2 Status is Not Enough: A Molecular Subtype Approach to Bladder Cancer is Also Needed . European Urology vol. 72 , ( 5 ) e137 - e138 .
Schmid P, Blackhall F, Muthukumar D, Lester J, Khan S, Adams J, Illsley M, Macgregor C et al. ( 2017 ) . A phase II, randomised, open-label study of gemcitabine/carboplatin first-line chemotherapy in combination with or without the antisense oligonucleotide apatorsen (OGX-427) in advanced squamous cell lung cancers . Annals of Oncology vol. 28 , v638 - v638 .
Shepherd STC, Hall P, Brown JE, Larkin JMG, Jones RJ, Ralph C, Hawkins RE, Chowdhury S et al. ( 2017 ) . Can dynamic changes in prognostic markers predict survival in patients receiving VEGF-targeted therapy in clear cell renal cell carcinoma? . Journal of Clinical Oncology . vol. 35 , e16061 - e16061 .
Ackerman C, Mariathasan S, Nickles D, Gomez De Liano Lista A, Wimalasingham AG, Szabados B, Powles T ( 2017 ) . Molecular subtyping of metastatic urothelial bladder cancer . Journal of Clinical Oncology . vol. 35 , 326 - 326 .
Powles T, Huddart RA, Elliott T, Sarker S-J, Ackerman C, Jones R, Hussain S, Crabb S et al. ( 2017 ) . Phase III, Double-Blind, Randomized Trial That Compared Maintenance Lapatinib Versus Placebo After First-Line Chemotherapy in Patients With Human Epidermal Growth Factor Receptor 1/2–Positive Metastatic Bladder Cancer . Journal of Clinical Oncology vol. 35 , ( 1 ) 48 - 55 .
Powles T, Huddart RA, Elliott T, Sarker S-J, Ackerman C, Jones R, Hussain S, Crabb S et al. ( 2016 ) . Phase III, Double-Blind, Randomized Trial That Compared Maintenance Lapatinib Versus Placebo After First-Line Chemotherapy in Patients With Human Epidermal Growth Factor Receptor 1/2-Positive Metastatic Bladder Cancer . Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 35 , ( 1 ) 48 - 55 .
Powles T, Sarwar N, Stockdale A, Sarker S-J, Boleti E, Protheroe A, Jones R, Chowdhury S et al. ( 2016 ) . Safety and Efficacy of Pazopanib Therapy Prior to Planned Nephrectomy in Metastatic Clear Cell Renal Cancer . JAMA Oncology vol. 2 , ( 10 ) 1303 - 1303 .
Powles T, Brown J, Larkin J, Jones R, Ralph C, Hawkins R, Chowdhury S, Boleti E et al. ( 2016 ) . A randomized, double-blind phase II study evaluating cediranib versus cediranib and saracatinib in patients with relapsed metastatic clear-cell renal cancer (COSAK) . Annals of Oncology vol. 27 , ( 5 ) 880 - 886 .
Powles T, Hussain SA, Protheroe A, Birtle A, Chakraborti PR, Huddart R, Jagdev S, Bahl A et al. ( 2016 ) . PLUTO: A randomised phase II study of pazopanib versus paclitaxel in relapsed urothelial tumours . Journal of Clinical Oncology . vol. 34 , 430 - 430 .
Sharpe K, Stewart GD, Mackay A, Van Neste C, Rofe C, Berney D, Kayani I, Bex A et al. ( 2013 ) . The Effect of VEGF-Targeted Therapy on Biomarker Expression in Sequential Tissue from Patients with Metastatic Clear Cell Renal Cancer . Clinical Cancer Research vol. 19 , ( 24 ) 6924 - 6934 .
Powles T, Kayani I, Blank CU, Chowdhury S, Horenblas S, Sarwar N, Nathan PD, Boleti E et al. ( 2010 ) . The safety and efficacy of sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer . Journal of Clinical Oncology vol. 28 , ( 15_suppl ) 4603 - 4603 .
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