Publications: P Jun Wang

( 2025 ) . The DNA mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression . Neoplasia vol. 67 , Article 101207 , 101207 - 101207 .

Peleva E, Chen Y, Finke B, Rizvi H, Healy E, Lai C, Craig P, Rickaby W et al. ( 2025 ) . P004 Enhanced metastasis risk prediction in cutaneous squamous cell carcinoma using deep learning and computational histopathology: cSCCNet development and evaluation . British Journal of Dermatology vol. 193 , ( Supplement_1 ) Article ljaf085.032 ,

Kaya F, Bewicke-Copley F, Miettinen JJ, Casado P, Leddy E, Deniz Ö, Lavallée V-P, Philippe C et al. ( 2025 ) . DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes . Leukemia vol. 39 , ( 6 ) 1526 - 1531 .

( 2025 ) . Genomic-transcriptomic analysis identifies the Syrian hamster as a superior animal model for human diseases . BMC Genomics vol. 26 , ( 1 ) Article 286 ,

Kaya F, Bewicke-Copley F, Miettinen JJ, Casado P, Leddy E, Deniz Ö, Lavallée V-P, Philippe C et al. ( 2025 ) . DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes .

( 2025 ) . The RNA-binding protein RSRC2 promotes mitotic fidelity by interacting with the lncRNA <i>C1QTNF1-AS1</i> .

Bojko J, Flynn B, Aschenbrenner B, Howard A, Lay E, Krajic N, Bailey E, Catalan S et al. ( 2024 ) . YAP engages RIF1 to dampen replication stress in squamous cell carcinoma .

( 2024 ) . A trafficking regulatory subnetwork governs α\n _V\n β\n ₆\n integrin-HER2 cross-talk to control breast cancer invasion and drug resistance . Science Advances vol. 10 , ( 49 ) Article eadk9944 ,

( 2024 ) . The DNA Mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression .

Elorbany S, Berlato C, Carnevalli LS, Maniati E, Barry ST, Wang J, Manchanda R, Kzhyshkowska J et al. ( 2024 ) . Immunotherapy that improves response to chemotherapy in high-grade serous ovarian cancer . Nature Communications vol. 15 , ( 1 ) Article 10144 ,

( 2024 ) . The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma . Nature Communications vol. 15 , ( 1 ) Article 8988 ,

( 2024 ) . <i>CREBBP</i> histone acetyltransferase domain mutations predict response to mTOR inhibition in relapsed/refractory follicular lymphoma . British Journal of Haematology vol. 205 , ( 5 ) 1804 - 1809 .

Constantinou M, Nicholson J, Zhang X, Maniati E, Lucchini S, Rosser G, Vinel C, Wang J et al. ( 2024 ) . Lineage specification in glioblastoma is regulated by METTL7B . Cell Reports vol. 43 , ( 6 ) Article 114309 , 114309 - 114309 .

Njegić A, Laid L, Zi M, Maniati E, Wang J, Chelu A, Wisniewski L, Hunter J et al. ( 2024 ) . Treatment with αvβ3-integrin-specific 29P attenuates pressure-overload induced cardiac remodelling after transverse aortic constriction in mice . Journal of Molecular and Cellular Cardiology Plus vol. 8 , Article 100069 , 100069 - 100069 .

Elorbany S, Berlato C, Carnevalli L, Barry S, Maniati E, Wang J, Manchanda R, Kzhyshkowska J et al. ( 2024 ) . Abstract 6553: Targeting macrophages and regulatory T cells improves response to chemotherapy in high-grade serous ovarian cancer . Cancer Research . vol. 84 , 6553 - 6553 .

( 2024 ) . Genomic-transcriptomic analysis reveals Syrian hamster as a superior human disease animal model .

( 2023 ) . Transcriptomic analysis of cutaneous squamous cell carcinoma reveals a multigene prognostic signature associated with metastasis . Journal of the American Academy of Dermatology vol. 89 , ( 6 ) 1159 - 1166 .

Zheng J, Bewicke-Copley F, Vermeulen C, Casado P, Kaya F, Demeulemeester J, Guscott M, Krizsán S et al. ( 2023 ) . Allele-Specific Expression of Leukemia Genes Is Associated with Pathogenicity in Poor Risk AML . Blood vol. 142 , ( Supplement 1 ) 1389 - 1389 .

Kaya F, Bewicke-Copley F, Casado Izquierdo P, Zheng J, Miettinen JJ, Khan N, Krizsán S, Saad JJ et al. ( 2023 ) . The XPO1-FOXC1-HOX Functional Axis Opens New Therapeutic Avenues to Treat DEK-NUP214 AML Patients . Blood vol. 142 , ( Supplement 1 ) 4302 - 4302 .

( 2023 ) . A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance .

( 2023 ) . A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance .

Wang J, Harwood C, Bailey E, Bewicke-Copley F, Anene C, Thomson J, Qamar M, Nourse C et al. ( 2023 ) . LB1663 A multi-gene prognostic signature associated with cutaneous squamous cell carcinoma metastasis . Journal of Investigative Dermatology vol. 143 , ( 9 ) B8 - B8 .

( 2023 ) . Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression . Nature Communications vol. 14 , ( 1 ) Article 5211 ,

Brito Baleeiro R, Liu P, Chard Dunmall LS, Di Gioia C, Nagano A, Cutmore L, Wang J, Chelala C et al. ( 2023 ) . Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancer . Journal for ImmunoTherapy of Cancer vol. 11 , ( 8 ) e007336 - e007336 .

Thomson J, Harwoood C, Strid J, Healy E, Wang J ( 2023 ) . O02 Neoantigens from actinic keratosis are predicted to be more immunogenic than those from cutaneous squamous cell carcinoma – a strategy for immune escape? . British Journal of Dermatology vol. 189 , ( 1 ) e4 - e5 .

Wang J, Patel M, Maniati E, Atanur S, Pal D, Rio-Machin A, Heward J, Kocher H et al. ( 2023 ) . Non-coding mutations at enhancer clusters contribute to pancreatic ductal adenocarcinoma .

Patel MB, Maniati E, Atanur SS, Pal D, Rio-Machin A, Heward J, Kocher HM, Fitzgibbon J et al. ( 2023 ) . Non-coding mutations at enhancer clusters contribute to pancreatic ductal adenocarcinoma .

Peleva E, Chen Y, Rizvi H, Harwood C, Wang J ( 2023 ) . 010 Enhanced outcome prediction in cutaneous squamous cell carcinoma using deep-learning and computational histopathology (cSCCnet) . British Journal of Dermatology vol. 188 , ( Supplement_4 ) Article ljad113.010 ,

Thomson J, Healy E, Strid J, Harwood C, Wang J ( 2023 ) . 274 Homologous recombination deficiency scores in AK and cSCC are associated with tumor-immune phenotype . Journal of Investigative Dermatology vol. 143 , ( 5 ) S47 - S47 .

Philippe C, Mian S, Maniati E, Protopapa P, Bergot T, Piganeau M, Nemkov T, Di Bella D et al. ( 2023 ) . TARGETING THE DEFECTIVE COA PATHWAY TO IMPROVE ERYTHROPOIESIS IN SF3B1-MUTANT MDS-RS PATIENTS . Leukemia Research vol. 128 , Article 107133 , 107133 - 107133 .

Elorbany S, Berlato C, Carnevalli L, Maniati E, Wang J, Barry S, Manchanda R, Kzhyshkowska J et al. ( 2023 ) . Abstract LB195: Immunotherapies that repolarize macrophages and CD4 T cells enhance the effect of chemotherapy in high-grade serous ovarian cancer . Cancer Research . vol. 83 , LB195 - LB195 .

Kumar R, Ibrahim R, Cheikh BB, Bailey E, Cottom H, Braubach O, Graham T, Wang J et al. ( 2023 ) . Abstract 5629: Spatial genomics and proteomics enable multimodal analyses of oral SCC clonal heterogeneity and interactions with tumor microenvironment . Cancer Research vol. 83 , ( 7_Supplement ) 5629 - 5629 .

Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S et al. ( 2023 ) . Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma . Blood Advances vol. 7 , ( 5 ) 845 - 855 .

Knight CH, Khan F, Patel A, Gill US, Okosun J, Wang J ( 2023 ) . IBRAP: integrated benchmarking single-cell RNA-sequencing analytical pipeline . Briefings Bioinform. vol. 24 , Article 2 ,

( 2023 ) . The EN-TEx resource of multi-tissue personal epigenomes &amp; variant-impact models . Cell vol. 186 , ( 7 ) 1493 - 1511.e40 .

Mian SA, Philippe C, Maniati E, Protopapa P, Bergot T, Piganeau M, Nemkov T, Di Bella D et al. ( 2023 ) . Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in\n <i>SF3B1</i>\n -mutated myelodysplasia . Science Translational Medicine vol. 15 , ( 685 ) Article eabn5135 ,

Wang J, Harwood C, Bailey E, Bewicke-Copley F, Anene C, Thomson J, Qamar M, Nourse C et al. ( 2023 ) . A multi-gene prognostic signature associated with cutaneous squamous cell carcinoma metastasis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 143 , B8 - B8 .

Baleeiro R, Liu P, Chard LS, Di Gioia C, Nagano A, Cutmore L, Wang J, Chelala C et al. ( 2023 ) . Emerging Data from the Use of TILT-123, an Oncolytic Adenovirus Armed with TNFa and IL-2 in Patients with Solid Tumors . MOLECULAR THERAPY . vol. 31 , 154 - 154 .

Thomson J, Healy E, Strid J, Harwood C, Wang J ( 2023 ) . Homologous recombination deficiency scores in AK and cSCC are associated with tumor-immune phenotype . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 143 , S47 - S47 .

Rio-Machin A, Bewicke-Copley F, Zheng J, Casado Izquierdo P, Miettinen JJ, Khan N, Demeulemeester J, Krizsán S et al. ( 2022 ) . Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML . Blood vol. 140 , ( Supplement 1 ) 1030 - 1032 .

Perrett M, Pickard L, Kumar E, Palladino G, Khan F, Edmondson C, Knight C, Poynton E et al. ( 2022 ) . Longitudinal Single Cell Analyses Reveal the Co-Evolutionary Dynamics of the Tumor and Microenvironment Accompanying Follicular Lymphoma Transformation . Blood vol. 140 , ( Supplement 1 ) 748 - 749 .

( 2022 ) . Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses . Genome Biology vol. 23 , ( 1 ) Article 223 ,

Knight CH, Khan F, Gill U, Wang J ( 2022 ) . IBRAP: Integrated Benchmarking Single-cell RNA-sequencing Analytical Pipeline .

Armes H, Bewicke‐Copley F, Rio‐Machin A, Di Bella D, Philippe C, Wozniak A, Tummala H, Wang J et al. ( 2022 ) . Germline ERCC excision repair 6 like 2 (<scp><i>ERCC6L2</i></scp>) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment . British Journal of Haematology vol. 199 , ( 5 ) 754 - 764 .

( 2022 ) . Discovery of mobocertinib, a new irreversible tyrosine kinase inhibitor indicated for the treatment of non-small-cell lung cancer harboring EGFR exon 20 insertion mutations . Medicinal Chemistry Research vol. 31 , ( 10 ) 1647 - 1662 .

D'Amico G, Fernandez I, Gómez-Escudero J, Kim H, Maniati E, Azman MS, Mardakheh FK, Serrels B et al. ( 2022 ) . ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning . Development vol. 149 , ( 13 ) Article dev200528 ,

( 2022 ) . Characterization of the Intra-tumoral B Cell Immunoglobulin Repertoire Is of Prognostic Value for Esophageal Squamous Cell Carcinoma . Frontiers in Immunology vol. 13 , Article 896627 ,

Anene CA, Taggart E, Harwood CA, Pennington DJ, Wang J ( 2022 ) . Decosus: An R Framework for Universal Integration of Cell Proportion Estimation Methods . Frontiers in Genetics vol. 13 , Article 802838 ,

Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A et al. ( 2022 ) . Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion . Cell Reports vol. 38 , ( 4 ) Article 110227 , 110227 - 110227 .

Walne AJ, Vulliamy T, Bewicke-Copley F, Wang J, Alnajar J, Bridger MG, Ma B, Tummala H et al. ( 2021 ) . Genome-wide whole-blood transcriptome profiling across inherited bone marrow failure subtypes . Blood Advances vol. 5 , ( 23 ) 5360 - 5371 .

Mian S, Philippe C, Maniati E, Bergot T, Piganeau M, Di Bella D, Morales V, Finch A et al. ( 2021 ) . Vitamin B5 and Succinyl-CoA Improve Ineffective Erythropoiesis in SF3B1 Mutated Myelodysplasia . Blood vol. 138 , ( Supplement 1 ) 324 - 324 .

Paredes-Redondo A, Harley P, Maniati E, Ryan D, Louzada S, Meng J, Kowala A, Fu B et al. ( 2021 ) . Optogenetic modeling of human neuromuscular circuits in Duchenne muscular dystrophy with CRISPR and pharmacological corrections . Science Advances vol. 7 , ( 37 ) Article eabi8787 ,

Jiang G, Wang Z, Cheng Z, Wang W, Zhang Z, Lu S, Xu H, Dong Y et al. ( 2021 ) . Stemness and NK-like signatures define a subtype of esophageal squamous cell carcinoma with poor prognosis .

( 2021 ) . The Genomic Landscape of Actinic Keratosis . Journal of Investigative Dermatology vol. 141 , ( 7 ) 1664 - 1674.e7 .

Anene CA, Khan F, Bewicke-Copley F, Maniati E, Wang J ( 2021 ) . ACSNI: An unsupervised machine-learning tool for prediction of tissue-specific pathway components using gene expression profiles . Patterns vol. 2 , ( 6 ) Article 100270 , 100270 - 100270 .

Freire-Benéitez V, Pomella N, Millner TO, Dumas AA, Niklison-Chirou MV, Maniati E, Wang J, Rajeeve V et al. ( 2021 ) . Correction to ‘Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma’ . NAR Cancer vol. 3 , ( 2 ) Article zcab020 ,

Heward J, Koniali L, D’Avola A, Close K, Yeomans A, Philpott M, Dunford J, Rahim T et al. ( 2021 ) . KDM5 inhibition offers a novel therapeutic strategy for the treatment of <i>KMT2D</i> mutant lymphomas . Blood vol. 138 , ( 5 ) 370 - 381 .

Freire-Benéitez V, Pomella N, Millner TO, Dumas AA, Niklison-Chirou MV, Maniati E, Wang J, Rajeeve V et al. ( 2021 ) . Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma . NAR Cancer vol. 3 , ( 1 ) Article zcab009 ,

Tse WY, Maniati E, Wang J, Lockley M, Martin S . Identification of a novel regulator of FANCD2 mediated DNA Repair . Proceedings of The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response . Conference: The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response from: 01/02/2021 to: 14/02/2021 , 9200 - 9200 .

( 2021 ) . The Transcriptomic Landscape of Prostate Cancer Development and Progression: An Integrative Analysis . Cancers vol. 13 , ( 2 ) 345 - 345 .

Keane L, Antignano I, Riechers S-P, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J et al. ( 2021 ) . mTOR-dependent translation amplifies microglia priming in aging mice . Journal of Clinical Investigation vol. 131 , ( 1 ) Article e132727 ,

( 2020 ) . Identification of Recurrent Mutations in the microRNA-Binding Sites of B-Cell Lymphoma-Associated Genes in Follicular Lymphoma . International Journal of Molecular Sciences vol. 21 , ( 22 ) 8795 - 8795 .

Tamura N, Shaikh N, Muliaditan D, Soliman TN, McGuinness JR, Maniati E, Moralli D, Durin M-A et al. ( 2020 ) . Specific Mechanisms of Chromosomal Instability Indicate Therapeutic Sensitivities in High-Grade Serous Ovarian Carcinoma . Cancer Research vol. 80 , ( 22 ) 4946 - 4959 .

Rio-Machin A, Casado-Izquierdo P, Miettinen J, Bewicke-Copley F, Khan N, Demeulemeester J, Krizsán S, Zheng J et al. ( 2020 ) . Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia . Blood vol. 136 , ( Supplement 1 ) 39 - 40 .

Uyulur F, Bewicke-Copley F, Anene CA, Schlesner M, MMML-Seq Project I, Siebert R, Okosun J, Fitzgibbon J et al. ( 2020 ) . Systematic Evaluation of Somatic <i>Cis</i>-Regulatory Mutations in Follicular Lymphoma . Blood vol. 136 , ( Supplement 1 ) 26 - 27 .

Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al. ( 2020 ) . Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer . npj Breast Cancer vol. 6 , ( 1 ) Article 38 ,

Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al. ( 2020 ) . Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer . NPJ breast cancer vol. 6 , ( 1 )

Iacovazzo D, Thong LC, Quezado R, Drummond J, Antonio DSBF, Cuenco J, Brändle M, Walker E et al. ( 2020 ) . The MAFA gene mutation responsible for familial insulinomatosis and diabetes impairs insulin secretion and results in downregulation of critical cell cycle regulators . Endocrine Abstracts

( 2020 ) . A frameshift variant in specificity protein 1 triggers superactivation of Sp1-mediated transcription in familial bone marrow failure . Proceedings of the National Academy of Sciences vol. 117 , ( 29 ) 17151 - 17155 .

Heward JA, Konali L, D’Avola A, Close K, Yeomans A, Philpott M, Dunford J, Rahim T et al. ( 2020 ) . KDM5 inhibition offers a novel therapeutic strategy for the treatment of<i>KMT2D</i>mutant lymphomas .

Gomez-Escudero J, Maniati E, Whiting F, Wang J, Graham T, Hodivala-Dilke K ( 2020 ) . Abstract A31: Tumor stroma in the development of acquired cancer therapy resistance . Cancer Research . vol. 80 , A31 - A31 .

Barbosa RR, Xu AQ, D’Andrea D, Copley F, Patel H, Chakravarty P, Clear A, Calaminici M et al. ( 2020 ) . Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability .

( 2020 ) . Genetic heterogeneity highlighted by differential FDG-PET response in diffuse large B-cell lymphoma . Haematologica vol. 105 , ( 6 ) 318 - 321 .

Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J et al. ( 2020 ) . Cancer associated fibroblast FAK regulates malignant cell metabolism . Nature Communications vol. 11 , ( 1 ) Article 1290 ,

( 2020 ) . The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants . Nature Communications vol. 11 , ( 1 ) Article 1044 ,

Lu S, Zhang Z, Du P, Chard LS, Yan W, El Khouri M, Wang Z, Zhang Z et al. ( 2020 ) . A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer . Clinical Cancer Research vol. 26 , ( 2 ) 465 - 476 .

Gomez-Escudero J, Maniati E, Whiting F, Wang J, Graham T, Hodivala-Dilke K ( 2020 ) . Tumor stroma in the development of acquired cancer therapy resistance . CANCER RESEARCH . vol. 80 , 48 - 48 .

Bewicke-Copley F, Korfi K, Araf S, Kumar EA, Cummin TEC, Ashton-Key M, Barrans S, Van Hoppe S et al. ( 2019 ) . Longitudinal Analyses of Diagnostic-Relapse Biopsies of Diffuse Large B Cell Lymphoma Reveal a Poor Risk Subset of ABC Patients Based on the Expression of a 30 Gene Panel . Blood vol. 134 , ( Supplement_1 ) 2769 - 2769 .

Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J et al. ( 2019 ) . Repurposing an anti‐cancer agent for the treatment of hypertrophic heart disease . The Journal of Pathology vol. 249 , ( 4 ) 523 - 535 .

Brown P, Tan A-C, El-Esawi MA, Liehr T, Blanck O, Gladue DP, Almeida GMF, Cernava T et al. ( 2019 ) . Large expert-curated database for benchmarking document similarity detection in biomedical literature search . Database vol. 2019 , Article baz085 ,

( 2019 ) . MLH1 deficiency leads to deregulated mitochondrial metabolism . Cell Death &amp; Disease vol. 10 , ( 11 ) Article 795 ,

Murtough S, Webb CM, Chikh A, Louis dit Picard H, Pink R, Wang J, Fitzgerald R, Risk J et al. ( 2019 ) . 423 Type 2 Immunity Linked to iRhom2 and Tylosis with Oesophageal Cancer . Journal of Investigative Dermatology . vol. 139 , S287 - S287 .

Mazzagatti A, Shaikh N, Bakker B, Spierings DCJ, Wardenaar R, Maniati E, Wang J, Boemo MA et al. ( 2019 ) . DNA Replication Stress Generates Distinctive Landscapes of DNA Copy Number Alterations and Chromosome Scale Losses .

( 2019 ) . Epigenetic Regulation of iASPP-p63 Feedback Loop in Cutaneous Squamous Cell Carcinoma . Journal of Investigative Dermatology vol. 139 , ( 8 ) 1658 - 1671.e8 .

( 2019 ) . A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing . International Journal of Molecular Sciences vol. 20 , ( 14 ) 3428 - 3428 .

Kumar E, Korfi K, Bewicke‐Copley F, Witzig T, Leukam M, Ansell S, Scott J, Rallis K et al. ( 2019 ) . PF513 MUTATIONS AFFECTING THE CREBBP HAT DOMAIN PREDICT RESPONSE TO MTOR INHIBITORS EVEROLIMUS AND TEMSIROLIMUS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA . HemaSphere vol. 3 , ( S1 ) 209 - 209 .

Korfi K, Araf S, Bewicke‐Copley F, Kumar E, Cummin T, Ashton‐Key M, Barrans S, Van Hoppe S et al. ( 2019 ) . LONGITUDINAL ANALYSES OF DIAGNOSTIC‐RELAPSE BIOPSIES OF DIFFUSE LARGE B CELL LYMPHOMA SUGGEST THAT RELAPSE IS MEDIATED BY DISTINCT MECHANISMS IN ABC AND GCB LYMPHOMA . Hematological Oncology vol. 37 , ( S2 ) 142 - 143 .

Kumar E, Korfi K, Bewicke-Copley F, Witzig T, Leukam M, Ansell S, Scott J, Rallis K et al. ( 2019 ) . MUTATIONS AFFECTING THE CREBBP HAT DOMAIN PREDICT RESPONSE TO MTOR INHIBITORS EVEROLIMUS AND TEMSIROLIMUS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA . HemaSphere vol. 3 , 209 - 209 .

Webb C, Murtough S, Chikh A, Louis dit Picard H, Wang J, Pink R, Risk JM, Fitzgerald RC et al. ( 2019 ) . 454 iRhom2-mediated immune dysregulation: Impact on the skin and oesophagus . Journal of Investigative Dermatology vol. 139 , ( 5 ) S78 - S78 .

( 2019 ) . Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma . Leukemia vol. 33 , ( 6 ) 1540 - 1540 .

( 2019 ) . Applications and analysis of targeted genomic sequencing in cancer studies . Computational and Structural Biotechnology Journal vol. 17 , 1348 - 1359 .

Webb C, Murtough S, Chikh A, Picard HLD, Wang J, Pink R, Risk JM, Fitzgerald RC et al. ( 2019 ) . iRhom2-mediated immune dysregulation: Impact on the skin and oesophagus . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 139 , S78 - S78 .

( 2018 ) . The Identification and Interpretation of cis-Regulatory Noncoding Mutations in Cancer . High-Throughput vol. 8 , ( 1 ) 1 - 1 .

( 2018 ) . The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature . Nature Communications vol. 9 , ( 1 ) Article 3667 ,

( 2018 ) . Transmission of diffuse large B-cell lymphoma by an allogeneic stem-cell transplant . Haematologica vol. 104 , ( 4 ) e174 - e177 .

( 2018 ) . MicroRNA and transcriptome analysis in periocular Sebaceous Gland Carcinoma . Scientific Reports vol. 8 , ( 1 ) Article 7531 ,

Dayem Ullah AZ, Oscanoa J, Wang J, Nagano A, Lemoine NR, Chelala C ( 2018 ) . SNPnexus: assessing the functional relevance of genetic variation to facilitate the promise of precision medicine . Nucleic Acids Research vol. 46 , ( W1 ) W109 - W113 .

( 2018 ) . CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype . Cell Reports vol. 23 , ( 5 ) 1448 - 1460 .

( 2018 ) . GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML . Leukemia vol. 32 , ( 11 ) 2502 - 2507 .

Pearce OMT, Delaine-Smith RM, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al. ( 2018 ) . Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers . Cancer Discovery vol. 8 , ( 3 ) 304 - 319 .

( 2018 ) . Diagnostic and prognostic potential of serum miR-132/212 cluster in patients with hepatocellular carcinoma . Annals of Clinical Biochemistry: International Journal of Laboratory Medicine vol. 55 , ( 5 ) 576 - 582 .

( 2018 ) . Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma . Leukemia vol. 32 , ( 5 ) 1261 - 1265 .

( 2018 ) . Hsa_circ_0014717 is downregulated in colorectal cancer and inhibits tumor growth by promoting p16 expression . Biomedicine &amp; Pharmacotherapy vol. 98 , 775 - 782 .

( 2018 ) . PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer . Cell Reports vol. 22 , ( 9 ) 2469 - 2481 .

( 2018 ) . IW-Scoring: an Integrative Weighted Scoring framework for annotating and prioritizing genetic variations in the noncoding genome . Nucleic Acids Research vol. 46 , ( 8 ) e47 - e47 .

Al Seraihi AF, Rio-Machin A, Tawana K, Bodor C, Wang J, Nagano A, Heward JA, Iqbal S et al. ( 2018 ) . <i>GATA2</i> monoallelic expression underlies reduced penetrance in inherited <i>GATA2</i>-mutated MDS/AML . LEUKEMIA vol. 32 , ( 11 ) 2502 - 2507 .

( 2018 ) . Exome sequencing of a cohort of actinic keratoses to identify significantly mutated genes . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E400 - E400 .

Klymenko T, Bloehdorn J, Bahlo J, Robrecht S, Akylzhanova G, Cox K, Estenfelder S, Wang J et al. ( 2017 ) . Lamin B1 regulates somatic mutations and progression of B-cell malignancies . Leukemia vol. 32 , ( 2 ) 364 - 375 .

Sangaralingam A, Dayem Ullah AZ, Marzec J, Gadaleta E, Nagano A, Ross-Adams H, Wang J, Lemoine NR et al. ( 2017 ) . ‘Multi-omic’ data analysis using O-miner . Briefings in Bioinformatics vol. 20 , ( 1 ) 130 - 143 .

Wang J, Ullah D, Chelala C ( 2017 ) . IW-Scoring: an Integrative Weighted Scoring framework for annotating and prioritizing genetic variations in the noncoding genome .

Balkwill FR, Pearce OM, Delaine-Smith R, Maniati E, Nichols S, Wang J, Bessant C, Knight M ( 2017 ) . Abstract 5558: Deconstruction of a human tumor microenvironment . Cancer Research . vol. 77 , 5558 - 5558 .

Wang J, Dumartin L, Mafficini A, Ulug P, Sangaralingam A, Alamiry NA, Radon TP, Salvia R et al. ( 2017 ) . Splice variants as novel targets in pancreatic ductal adenocarcinoma . Scientific Reports vol. 7 , ( 1 ) Article 2980 ,

( 2017 ) . Recurrent somatic JAK-STAT pathway variants within a RUNX1-mutated pedigree . European Journal of Human Genetics vol. 25 , ( 8 ) 1020 - 1024 .

Ironside A, Hawkesford K, Gomm J, Haywood L, Goulding I, Wang J, Lamaziere A, Poirot M et al. ( 2017 ) . Abstract P4-15-04: Molecular mediators of mammographic density . Cancer Research . vol. 77 ,

Harwood C, Proby C, Wang J, Nagano A, Alexandrov L, Purdie K, Chelala C, Inman G et al. ( 2017 ) . Chronic azathioprine treatment is causal in cutaneous squamous cell carcinoma development and is associated with a novel mutational signature . BRITISH JOURNAL OF DERMATOLOGY . vol. 177 , 9 - 10 .

Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward JA et al. ( 2017 ) . Genomic Profiling Reveals Spatial Intra-Tumor Heterogeneity in Follicular Lymphoma . BLOOD . vol. 130 ,

Klymenko T, Bloehdorn J, Bahlo J, Robrecht S, Wang J, Fischer K, Akylzhanova G, Edelmann J et al. ( 2017 ) . NUCLEAR LAMINA REGULATES SOMATIC HYPERMUTATION AND PROGRESSION OF B CELL MALIGNANCIES . HAEMATOLOGICA . vol. 102 , 228 - 228 .

( 2016 ) . Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma . Nature Communications vol. 7 , ( 1 ) Article 12493 ,

( 2016 ) . Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma . Cancer Research vol. 76 , ( 16 ) 4861 - 4871 .

( 2016 ) . Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1 . Cell Reports vol. 16 , ( 6 ) 1604 - 1613 .

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