Publications: PROF Qingzhong Xiao

Sun X, Wu J, He T, Yao M, Qin L, Weng C, Peng L, Xiao Q et al. ( 2025 ) . Mitochondrial One-Carbon Metabolism Drives CD34-Lineage Cells to Differentiate Into T Follicular Helper Cells to Form Tertiary Lymphoid Organs in Transplant Arteriosclerosis . Circulation vol. 152 , ( 8 ) 537 - 554 .

Zheng A, Yang M, Silveira Martinez C, Yang Z, Chen Q, Zhao H, Wang L, Zhang L et al. ( 2025 ) . BS53 Neutrophil elastase: a novel therapeutic target for heart failure with preserved ejection fraction . Stable IHD/Prevention/Hypertension/Lipids . Conference: British Cardiovascular Society Annual Conference, ‘The Risk Business, 2–4 June 2025A275.2 - A276 .

Xiao R, Darr H, Khan Z, Xiao Q ( 2025 ) . Updated Applications of Stem Cells in Hypoplastic Left Heart Syndrome .

Chen Q, Sun S, Shi Z, Wang L, Wang Y, Zheng A, Xu X, Yang M et al. ( 2025 ) . Novel roles of Nrf3–Trim5 axis in vascular smooth muscle cell dysfunctions and neointimal hyperplasia . Cardiovascular Research vol. 121 , ( 8 ) 1282 - 1298 .

Chen Q, Zheng A, Xu X, Shi Z, Yang M, Sun S, Wang L, Wang Y et al. ( 2025 ) . Nrf3-Mediated Mitochondrial Superoxide Promotes Cardiomyocyte Apoptosis and Impairs Cardiac Functions by Suppressing Pitx2 . Circulation vol. 151 , ( 14 ) 1024 - 1046 .

Tang Y, Wu J, Sun X, Tan S, Li W, Yin S, Liu L, Chen Y et al. ( 2025 ) . Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia . Cell Reports vol. 44 , ( 3 ) Article 115395 , 115395 - 115395 .

An W, Luo J, Zhang C, Xiao Q ( 2025 ) . Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2 . Journal of Inflammation Research vol. Volume 18 , 1377 - 1394 .

Wu H, Yang X, Chen T, Yu B, Chen M, Wang T, Jiang L, Zhang B et al. ( 2024 ) . Aneurysm Is Restricted by CD34⁺ Cell‐Formed Fibrous Collars Through the PDGFRb‐PI3K Axis . Advanced Science vol. 12 , ( 7 ) Article 2408996 ,

Niu K, Zhang C, Liu C, Wu W, Yan Y, Zheng A, Liu S, Shi Z et al. ( 2024 ) . An unexpected role of IL10 in mesoderm induction and differentiation from pluripotent stem cells: Implications in zebrafish angiogenic sprouting, vascular organoid development, and therapeutic angiogenesis . European Journal of Cell Biology vol. 103 , ( 4 ) Article 151465 , 151465 - 151465 .

Martinez CS, Zheng A, Xiao Q ( 2024 ) . Mitochondrial Reactive Oxygen Species Dysregulation in Heart Failure with Preserved Ejection Fraction: A Fraction of the Whole . Antioxidants vol. 13 , ( 11 ) 1330 - 1330 .

Zheng A, Chen Q, Shi Z, Xu X, Yang M, Sun S, Wang L, Wang Y et al. ( 2024 ) . NRF3-mediated mitochondrial superoxide promotes cardiomyocyte apoptosis and impairs cardiac functions by suppressing Pitx2 . European Heart Journal vol. 45 , ( Supplement_1 ) Article ehae666.1487 ,

Martinez CS, Zheng A, Xiao Q ( 2024 ) . Mitochondrial Reactive Oxygen Species Dysregulation in Heart Failure with Preserved Ejection Fraction: A Fraction of the Whole .

Cheruku GR, Wilson CV, Raviendran S, Xiao Q ( 2024 ) . Recent Advances and Future Perspectives in Vascular Organoids and Vessel-on-Chip . Organoids vol. 3 , ( 3 ) 203 - 246 .

Zhang Y, Guan Z, Gong H, Ni Z, Xiao Q, Guo X, Xu Q ( 2024 ) . The Role of Progenitor Cells in the Pathogenesis of Arteriosclerosis . Cardiology Discovery vol. 4 , ( 3 ) 231 - 244 .

Li Z, Wu W, Li Q, Heng X, Zhang W, Zhu Y, Chen L, Chen Z et al. ( 2024 ) . BCL6B-dependent suppression of ETV2 hampers endothelial cell differentiation . Stem Cell Research & Therapy vol. 15 , ( 1 ) Article 226 ,

Cheruku GR, Wilson CV, Raviendran S, Xiao Q ( 2024 ) . Recent Advances and Future Perspectives in Vascular Organoids and Vessel-on-Chip .

Tang Y, Wu J, Sun X, Tan S, Li W, Yin S, Liu L, Chen Y et al. ( 2024 ) . Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia . Cell Reports vol. 43 , ( 5 ) Article 114237 , 114237 - 114237 .

Sun X, Wu J, Zhang X, Xie C, Wei H, Li P, Yang Y, Yuan H et al. ( 2024 ) . Atlas of Cell Repertoire Within Neointimal Lesions Is Metabolically Altered in Hypertensive Rats . Hypertension vol. 81 , ( 4 ) 787 - 800 .

Niu K, Zhang C, Yang M, Maguire EM, Shi Z, Sun S, Wu J, Liu C et al. ( 2024 ) . Small nucleolar RNA host gene 18 controls vascular smooth muscle cell contractile phenotype and neointimal hyperplasia . Cardiovascular Research vol. 120 , ( 7 ) 796 - 810 .

Swiatlowska P, Tipping W, Marhuenda E, Severi P, Fomin V, Yang Z, Xiao Q, Graham D et al. ( 2024 ) . Hypertensive Pressure Mechanosensing Alone Triggers Lipid Droplet Accumulation and Transdifferentiation of Vascular Smooth Muscle Cells to Foam Cells (Adv. Sci. 9/2024) . Advanced Science vol. 11 , ( 9 ) Article 2470050 ,

Li Z, Wu W, Li Q, Heng X, Zhang W, Zhu Y, Chen L, Chen Z et al. ( 2024 ) . BCL6B-dependent Suppression of ETV2 Hampers Endothelial Cell Differentiation .

Swiatlowska P, Tipping W, Marhuenda E, Severi P, Fomin V, Yang Z, Xiao Q, Graham D et al. ( 2023 ) . Hypertensive Pressure Mechanosensing Alone Triggers Lipid Droplet Accumulation and Transdifferentiation of Vascular Smooth Muscle Cells to Foam Cells . Advanced Science vol. 11 , ( 9 ) Article 2308686 ,

Liu S, Fang C, Zhong C, Li J, Xiao Q ( 2023 ) . Recent advances in pluripotent stem cell-derived cardiac organoids and heart-on-chip applications for studying anti-cancer drug-induced cardiotoxicity . Cell Biology and Toxicology vol. 39 , ( 6 ) 2527 - 2549 .

Yang M, Zhou X, Pearce SWA, Yang Z, Chen Q, Niu K, Liu C, Luo J et al. ( 2023 ) . Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 43 , ( 10 ) 1900 - 1920 .

Sun X, Lu Y, Wu J, Wen Q, Li Z, Tang Y, Shi Y, He T et al. ( 2023 ) . Meta-Analysis of Single-Cell RNA-Seq Data Reveals the Mechanism of Formation and Heterogeneity of Tertiary Lymphoid Organ in Vascular Disease . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 43 , ( 10 ) 1867 - 1886 .

Liu S-S, Maguire EM, Bai Y-S, Huang L, Liu Y, Xu L, Fauzi I, Zhang S-Q et al. ( 2023 ) . A Novel Regulatory Axis, CHD1L-MicroRNA 486-Matrix Metalloproteinase 2, Controls Spermatogonial Stem Cell Properties . Molecular and Cellular Biology vol. 39 , ( 4 ) Article e00357-18 ,

Chen K, Mou R, Zhu P, Xu X, Wang H, Jiang L, Hu Y, Hu X et al. ( 2023 ) . The Effect of Lymphangiogenesis in Transplant Arteriosclerosis . Circulation vol. 147 , ( 6 ) 482 - 497 .

Swiatlowska P, Sit B, Feng Z, Zhou X, Xiao Q, Shanahan C, Yu C, Iskratsch T ( 2023 ) . Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching . MOLECULAR BIOLOGY OF THE CELL . vol. 34 , 740 - 741 .

Sellahewa SG, Li JY, Xiao Q ( 2022 ) . Updated Perspectives on Direct Vascular Cellular Reprogramming and Their Potential Applications in Tissue Engineered Vascular Grafts . Journal of Functional Biomaterials vol. 14 , ( 1 ) 21 - 21 .

Meng X, Wu T, Lou Q, Niu K, Jiang L, Xiao Q, Xu T, Zhang L ( 2022 ) . Optimization of <scp>CRISPR–Cas</scp> system for clinical cancer therapy . Bioengineering &amp; Translational Medicine vol. 8 , ( 2 ) Article e10474 ,

Efovi D, Xiao Q ( 2022 ) . Noncoding RNAs in Vascular Cell Biology and Restenosis . Biology vol. 12 , ( 1 ) 24 - 24 .

Karamanavi E, McVey DG, van der Laan SW, Stanczyk PJ, Morris GE, Wang Y, Yang W, Chan K et al. ( 2022 ) . The\n <i>FES</i>\n Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis . Circulation Research vol. 131 , ( 12 ) 1004 - 1017 .

Swiatlowska P, Sit B, Feng Z, Marhuenda E, Zhou X, Xiao Q, Shanahan C, Yu C-H et al. ( 2022 ) . Mechanoregulation of vascular smooth muscle cells phenotype in atherosclerosis . Journal of Molecular and Cellular Cardiology vol. 173 , S41 - S42 .

Zhou K, Chen H, Wang X-Y, Xu Y-M, Liao Y-F, Qin Y-Y, Ge X-W, Zhang T-T et al. ( 2022 ) . Targeted pharmacokinetics and bioinformatics screening strategy reveals JAK2 as the main target for Xin-Ji-Er-Kang in treatment of MIR injury . Biomedicine &amp; Pharmacotherapy vol. 155 , Article 113792 , 113792 - 113792 .

Zhang C, Niu K, Ren M, Zhou X, Yang Z, Yang M, Wang X, Luo J et al. ( 2022 ) . Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model . Cells vol. 11 , ( 20 ) 3218 - 3218 .

Yang S, Wang C, Ruan C, Chen M, Cao R, Sheng L, Chang N, Xu T et al. ( 2022 ) . Novel Insights into the Cardioprotective Effects of Calcitriol in Myocardial Infarction . Cells vol. 11 , ( 10 ) 1676 - 1676 .

Swiatlowska P, Sit B, Feng Z, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X et al. ( 2022 ) . Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching . Science Advances vol. 8 , ( 15 ) Article eabm3471 ,

Pan M, Cheng Z-W, Huang C-G, Ye Z-Q, Sun L-J, Chen H, Fu B-B, Zhou K et al. ( 2022 ) . Long-term exposure to copper induces mitochondria-mediated apoptosis in mouse hearts . Ecotoxicology and Environmental Safety vol. 234 , Article 113329 , 113329 - 113329 .

Yan Y, Xu Y, Yang X, Li Z, Niu K, Liu C, Zhao M, Xiao Q et al. ( 2022 ) . Electron Transfer Flavoprotein (ETF) <i>α</i> Controls Blood Vessel Development by Regulating Endothelial Mitochondrial Bioenergetics and Oxygen Consumption . Oxidative Medicine and Cellular Longevity vol. 2022 , ( 1 ) Article 7969916 ,

Yao L, Hao Y, Wen G, Xiao Q, Wu P, Wang J, Liu J ( 2022 ) . Induction of Heme Oxygenase-1 Modifies the Systemic Immunity and Reduces Atherosclerotic Lesion Development in ApoE Deficient Mice . Frontiers in Pharmacology vol. 13 , Article 809469 ,

Yang M, Chen Q, Mei L, Wen G, An W, Zhou X, Niu K, Liu C et al. ( 2021 ) . Neutrophil elastase promotes neointimal hyperplasia by targeting toll‐like receptor 4 (TLR4)–NF‐κB signalling . British Journal of Pharmacology vol. 178 , ( 20 ) 4048 - 4068 .

Zhang C, Niu K, Lian P, Hu Y, Shuai Z, Gao S, Ge S, Xu T et al. ( 2021 ) . Pathological Bases and Clinical Application of Long Noncoding RNAs in Cardiovascular Diseases . Hypertension vol. 78 , ( 1 ) 16 - 29 .

Hu L-L, Zou K, Chen Y, Wu L-J, Cao J, Xiong X-Y, Wang L, Cheng X-S et al. ( 2021 ) . Functional role and molecular mechanisms underlying prohibitin 2 in platelet mitophagy and activation . Molecular Medicine Reports vol. 23 , ( 5 ) Article 384 ,

An W, Luong LA, Bowden NP, Yang M, Wu W, Zhou X, Liu C, Niu K et al. ( 2021 ) . Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling . Cardiovascular Research vol. 118 , ( 2 ) 638 - 653 .

Swiatlowska P, Sit B, Feng Z, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X et al. ( 2020 ) . Matrix stiffness and blood pressure together regulate vascular smooth muscle cell phenotype switching .

Chen D, Zhang C, Chen J, Yang M, Afzal TA, An W, Maguire EM, He S et al. ( 2020 ) . <scp>miRNA</scp>‐200c‐<scp>3p</scp> promotes endothelial to mesenchymal transition and neointimal hyperplasia in artery bypass grafts . The Journal of Pathology vol. 253 , ( 2 ) 209 - 224 .

He S, Yang F, Yang M, An W, Maguire EM, Chen Q, Xiao R, Wu W et al. ( 2020 ) . miR-214-3p-Sufu-GLI1 is a novel regulatory axis controlling inflammatory smooth muscle cell differentiation from stem cells and neointimal hyperplasia . Stem Cell Research &amp; Therapy vol. 11 , ( 1 ) Article 465 ,

Liu C, Niu K, Xiao Q ( 2020 ) . Updated perspectives on vascular cell specification and pluripotent stem cell-derived vascular organoids for studying vasculopathies . Cardiovascular Research vol. 118 , ( 1 ) 97 - 114 .

Cai J, Deng J, Gu W, Ni Z, Liu Y, Kamra Y, Saxena A, Hu Y et al. ( 2020 ) . Impact of Local Alloimmunity and Recipient Cells in Transplant Arteriosclerosis . Circulation Research vol. 127 , ( 8 ) 974 - 993 .

Maguire EM, Xiao Q ( 2020 ) . Noncoding RNAs in vascular smooth muscle cell function and neointimal hyperplasia . The FEBS Journal vol. 287 , ( 24 ) 5260 - 5283 .

Pu X, Chan K, Yang W, Xiao Q, Zhang L, Moore AD, Liu C, Webb TR et al. ( 2020 ) . Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis . Atherosclerosis vol. 296 , 11 - 17 .

Maguire EM, Pearce SWA, Xiao R, Oo AY, Xiao Q ( 2019 ) . Matrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection . Pharmaceuticals vol. 12 , ( 3 ) 118 - 118 .

Pearce S, Xiao Q, Wu W, An W, Yang M ( 2019 ) . BS38 Role of neutrophil elastase in abdominal aortic aneurysms and thoracic aortic dissection . Basic Science . Conference: British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019A164.2 - A164 .

Yang F, Chen Q, Yang M, Maguire EM, Yu X, He S, Xiao R, Wang CS et al. ( 2019 ) . Macrophage-derived MMP-8 determines smooth muscle cell differentiation from adventitia stem/progenitor cells and promotes neointima hyperplasia . Cardiovascular Research vol. 116 , ( 1 ) 211 - 225 .

Maguire EM, Pearce SWA, Xiao Q ( 2019 ) . Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease . Vascular Pharmacology vol. 112 , 54 - 71 .

Bonacina F, Coe D, Wang G, Longhi MP, Baragetti A, Moregola A, Garlaschelli K, Uboldi P et al. ( 2018 ) . Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation . Nature Communications vol. 9 , ( 1 ) Article 3083 ,

Xiao Q ( 2018 ) . 119 Macrophage-derived MMP-8 determines vascular smooth muscle cell differentiation from adventitia stem cells and promotes neointima hyperplasia . Basic Science . Conference: British Cardiovascular Society Annual Conference ‘High Performing Teams’, 4–6 June 2018, Manchester, UKA91.2 - A91 .

Xiao Q, He S ( 2018 ) . 139 Microrna-214 is a novel player in inflammatory smooth muscle cell differentiation and angioplasty restenosis . Basic Science . Conference: British Cardiovascular Society Annual Conference ‘High Performing Teams’, 4–6 June 2018, Manchester, UKA102.1 - A102 .

Yang F, Chen Q, He S, Yang M, Maguire EM, An W, Afzal TA, Luong LA et al. ( 2018 ) . miR-22 Is a Novel Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation and Neointima Formation . Circulation vol. 137 , ( 17 ) 1824 - 1841 .

Wen G, An W, Chen J, Maguire EM, Chen Q, Yang F, Pearce SWA, Kyriakides M et al. ( 2018 ) . Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis . Journal of the American Heart Association vol. 7 , ( 4 ) Article e008187 ,

Zhang C, Chen D, Maguire EM, He S, Chen J, An W, Yang M, Afzal TA et al. ( 2017 ) . Cbx3 inhibits vascular smooth muscle cell proliferation, migration, and neointima formation . Cardiovascular Research vol. 114 , ( 3 ) 443 - 455 .

Wang G, Luo Z, Xu Q, Xiao Q ( 2017 ) . The mechanism of stem cell differentiation into smooth muscle cells . Thrombosis and Haemostasis vol. 104 , ( 09 ) 440 - 448 .

Maguire EM, Xiao Q, Xu Q ( 2017 ) . Differentiation and Application of Induced Pluripotent Stem Cell–Derived Vascular Smooth Muscle Cells . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 37 , ( 11 ) 2026 - 2037 .

Zhang L, Chen Q, An W, Yang F, Maguire EM, Chen D, Zhang C, Wen G et al. ( 2017 ) . Novel Pathological Role of hnRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1) in Vascular Smooth Muscle Cell Function and Neointima Hyperplasia . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 37 , ( 11 ) 2182 - 2194 .

Ren M, Ng FL, Warren HR, Witkowska K, Baron M, Jia Z, Cabrera C, Zhang R et al. ( 2017 ) . The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle . Human Molecular Genetics vol. 27 , ( 1 ) 199 - 210 .

Xiao Q ( 2017 ) . A novel pathological role of hnRNPA1 in vascular smooth muscle cell functions and neointima hyperplasia . Atherosclerosis . vol. 263 , e19 - e19 .

Chen Q, Wang Q, Zhu J, Xiao Q, Zhang L ( 2017 ) . Reactive oxygen species: key regulators in vascular health and diseases . British Journal of Pharmacology vol. 175 , ( 8 ) 1279 - 1292 .

Khambata RS, Ghosh SM, Rathod KS, Thevathasan T, Filomena F, Xiao Q, Ahluwalia A ( 2017 ) . Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque . Proceedings of the National Academy of Sciences vol. 114 , ( 4 )

Xiao Q ( 2017 ) . Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Prevents Experimental Atherosclerosis by Inhibiting Foam Cell Formation . JOURNAL OF VASCULAR RESEARCH . vol. 54 , 9 - 9 .

Afzal TA, Luong LA, Chen D, Zhang C, Yang F, Chen Q, An W, Wilkes E et al. ( 2016 ) . NCK Associated Protein 1 Modulated by miRNA‐214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia . Journal of the American Heart Association vol. 5 , ( 12 ) Article e004629 ,

Ren M, Ng F, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S et al. ( 2016 ) . [OP.7C.08] BLOOD-PRESSURE ASSOCIATED VARIANTS IN NPR3 AFFECT HUMAN VASCULAR SMOOTH MUSCLE CELLS PROLIFERATION AND CALCIUM RESPONSE TO ANGIOTENSIN II . vol. 34 , is. Supplement 2 , pp. e92 - e92 . Ovid Technologies (Wolters Kluwer Health)

Yang W, Ng FL, Chan K, Pu X, Poston RN, Ren M, An W, Zhang R et al. ( 2016 ) . Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction . PLOS Genetics vol. 12 , ( 7 ) e1006127 - e1006127 .

Afzal TA, Xiao Q ( 2016 ) . 173 Functional Role of microRNA-214 in Modulating Vascular Smooth Muscle Cell Functions and Neointima Formation . Heart . vol. 102 , A121.1 - A121 .

AN W, Xiao Q ( 2016 ) . 174 hnRNPA1 is A Critical Regulator in Vascular Smooth Muscle Cell Functions and Neointima Hyperplasia . Heart . vol. 102 , A121.2 - A121 .

Yang F, Xiao Q ( 2016 ) . 197 miRNA-22 Regulates Vascular Smooth Muscle Cell Functions and Prevents Neointima Formation by Targeting EVI-1 . Heart . vol. 102 , A132.3 - A133 .

Yang F, Chen Q, Wen G, Zhang C, Luong LA, Zhu J, Zhang L, Xiao Q ( 2016 ) . Functional role of miRNA-34A in smooth muscle cell functions and neointima formation . Atherosclerosis vol. 244 , e3 - e4 .

Chen Q, Yang F, Guo M, Wen G, Zhang C, Luong LA, Zhu J, Xiao Q et al. ( 2015 ) . miRNA-34a reduces neointima formation through inhibiting smooth muscle cell proliferation and migration . Journal of Molecular and Cellular Cardiology vol. 89 , 75 - 86 .

Zeng L, Li Y, Yang J, Wang G, Margariti A, Xiao Q, Zampetaki A, Yin X et al. ( 2015 ) . XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 35 , ( 10 ) 2134 - 2144 .

Ren M, Ng FL, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S et al. ( 2015 ) . Abstract P048: Blood-Pressure Associated Variants in Natriuretic Peptide Receptor C Affect Human Vascular Smooth Muscle Cells Proliferation and Calcium Flux in Response to Angiotensin II . Hypertension vol. 66 , ( suppl_1 )

Wen G, Zhang C, Chen Q, Luong LA, Mustafa A, Ye S, Xiao Q ( 2015 ) . A Novel Role of Matrix Metalloproteinase-8 in Macrophage Differentiation and Polarization . Journal of Biological Chemistry vol. 290 , ( 31 ) 19158 - 19172 .

Zhao H, Wen G, Huang Y, Yu X, Chen Q, Luong L, Zhu J, Ye S et al. ( 2015 ) . Methyl CPG binding protein 2 inhibition by microRNA-22 is required for stem cell differentiation towards smooth muscle cells . Atherosclerosis . vol. 241 , e18 - e19 .

Wen G, Chen Q, Luong L, Mustafa A, Ye S, Xiao Q ( 2015 ) . Unexpected role of matrix metalloproteinase-8 (MMP8) in macrophage polarization . Atherosclerosis . vol. 241 , e62 - e62 .

Xiao Q, Chen Q, Yang F ( 2015 ) . 211 Mirna-34a Reduces Neointima fommation through Inhibiting Smooth Muscle Cell Proliferation and Migration . Heart . vol. 101 , A116.1 - A116 .

Ren M, Ng F, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S et al. ( 2015 ) . PP.LB03.07 . Journal of Hypertension . vol. 33 , e518 - e519 .

Zhao H, Wen G, Huang Y, Yu X, Chen Q, Afzal TA, Luong LA, Zhu J et al. ( 2015 ) . MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG–Binding Protein 2 . Arteriosclerosis, Thrombosis, and Vascular Biology . vol. 35 , 918 - 929 .

Ren M, Ng FL, Witkowska K, Baron M, Townsend-Nicholson A, Xiao Q, Hobbs A, Ye S et al. ( 2015 ) . Blood-pressure associated variants in <i>NPR3</i> affect human vascular smooth muscle cells proliferation and calcium response to angiotensin II . vol. 29 , is. 10 , pp. 624 - 624 .

Chen Q, Wen G, Huang Y, Luong L, Zhu J, Zhang L, Xiao Q ( 2015 ) . Hnrnpa1 is a critical regulator in vascular smooth muscle cell functions and neointima hyperplasia . EUROPEAN HEART JOURNAL . vol. 36 , 1025 - 1025 .

Zhao H, Wen G, Huang Y, Yu X, Chen Q, Afzal TA, Luong LA, Zhu J et al. ( 2015 ) . MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG-Binding Protein 2 . ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY vol. 35 , ( 4 ) 918 - 929 .

Yu X, Zhang L, Wen G, Zhao H, Luong LA, Chen Q, Huang Y, Zhu J et al. ( 2015 ) . Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells . CELL DEATH AND DIFFERENTIATION vol. 22 , ( 7 ) 1170 - 1180 .

Yu X, Zhang L, Wen G, Zhao H, Luong LA, Chen Q, Huang Y, Zhu J et al. ( 2014 ) . Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells . Cell Death &amp; Differentiation vol. 22 , ( 7 ) 1170 - 1180 .

Wen G, Chen Q, Luong LA, Mustafa A, Shu Y, Xiao Q ( 2014 ) . Matrix metalloproteinase-8 (MMP8) modulates M2 macrophage polarization and molecular mechanisms involved . Atherosclerosis vol. 237 , ( 2 ) e15 - e15 .

Zhao H, Wen G, Huang Y, Yu X, Chen Q, Afzal TA, Luong LA, Zhu J et al. ( 2014 ) . MicroRNA-22 regulates smooth muscle cell differentiation from stem cells by targeting methyl CpG binding protein 2 . Atherosclerosis vol. 237 , ( 2 ) e15 - e15 .

Zhao H, Huang Y, Yu X, Wen G, Ye S, Zhang L, Xiao Q ( 2014 ) . Microrna-22 regulates smooth muscle cell differentiation from stem cells by targeting methyl cpg binding protein 2 . Atherosclerosis . vol. 235 , e130 - e131 .

Xiao Q, Zhang F, Grassia G, Hu Y, Zhang Z, Xing Q, Yin X, Maddaluno M et al. ( 2014 ) . Matrix Metalloproteinase-8 Promotes Vascular Smooth Muscle Cell Proliferation and Neointima Formation . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 34 , ( 1 ) 90 - 98 .

Zeng L, Wang G, Ummarino D, Margariti A, Xu Q, Xiao Q, Wang W, Zhang Z et al. ( 2013 ) . Histone Deacetylase 3 Unconventional Splicing Mediates Endothelial-to-mesenchymal Transition through Transforming Growth Factor β2 . Journal of Biological Chemistry vol. 288 , ( 44 ) 31853 - 31866 .

Luo Z, Wen G, Wang G, Pu X, Ye S, Xu Q, Wang W, Xiao Q ( 2013 ) . MicroRNA-200C and -150 play an important role in endothelial cell differentiation and vasculogenesis by targeting transcription repressor ZEB1 . Stem Cells vol. 31 , ( 9 ) 1749 - 1762 .

Ali ZA, Rinze R, Douglas G, Hu Y, Xiao Q, Qi W, McNeill E, Bursill C et al. ( 2013 ) . Tetrahydrobiopterin Determines Vascular Remodeling Through Enhanced Endothelial Cell Survival and Regeneration . Circulation . vol. 128 ,

Zhao H, Huang Y, Yu X, Wen G, Wang W, Ye S, Xiao Q ( 2013 ) . Abstract 004: Microrna-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells By Targeting Methyl Cpg Binding Protein 2 . Circulation Research vol. 113 , ( suppl_1 )

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al. ( 2013 ) . YIA3: ADAMTS7 CLEAVAGE AND VASCULAR SMOOTH MUSCLE CELL MIGRATION IS AFFECTED BY A CORONARY ARTERY DISEASE ASSOCIATED VARIANT . Heart . vol. 99 , A5 - A6 .

Huang Y, Lin L, Yu X, Wen G, Pu X, Zhao H, Fang C, Zhu J et al. ( 2013 ) . Functional Involvements of Heterogeneous Nuclear Ribonucleoprotein A1 in Smooth Muscle Differentiation from Stem Cells In Vitro and In Vivo . Stem Cells vol. 31 , ( 5 ) 906 - 917 .

Zeng L, Xiao Q, Chen M, Margariti A, Martin D, Ivetic A, Xu H, Mason J et al. ( 2013 ) . Vascular Endothelial Cell Growth–Activated XBP1 Splicing in Endothelial Cells Is Crucial for Angiogenesis . Circulation vol. 127 , ( 16 ) 1712 - 1722 .

Fang C, Wen G, Zhang L, Lin L, Moore A, Wu S, Ye S, Xiao Q ( 2013 ) . An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivo . Cardiovascular Research vol. 99 , ( 1 ) 146 - 155 .

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al. ( 2013 ) . ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant . American Journal of Human Genetics vol. 92 , ( 3 ) 366 - 374 .

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al. ( 2013 ) . ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant . The American Journal of Human Genetics vol. 92 , ( 3 ) 366 - 374 .

Xiao Q, Zhang F, Lin L, Fang C, Wen G, Tsai T-N, Pu X, Sims D et al. ( 2013 ) . Functional Role of Matrix Metalloproteinase-8 in Stem/Progenitor Cell Migration and Their Recruitment Into Atherosclerotic Lesions . Circulation Research vol. 112 , ( 1 ) 35 - 47 .

Zheng X, Wu Y, Zhu L, Chen Q, Zhou Y, Yan H, Chen T, Xiao Q et al. ( 2013 ) . Angiotensin II promotes differentiation of mouse embryonic stem cells to smooth muscle cells through PI3-kinase signaling pathway and NF-κB . Differentiation vol. 85 , ( 1-2 ) 41 - 54 .

Chen Q, Jin M, Zhu J, Xiao Q, Zhang L ( 2013 ) . Functions of Heterogeneous Nuclear Ribonucleoproteins in Stem Cell Potency and Differentiation . BioMed Research International vol. 2013 , 1 - 12 .

Chen Q, Jin M, Yang F, Zhu J, Xiao Q, Zhang L ( 2013 ) . Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling . Mediators of Inflammation vol. 2013 , 1 - 14 .

Yu X, Zhang L, Wen G, Zhao H, Huang Y, Zhu J, Xu Q, Ye S et al. ( 2013 ) . MicroRNA-34a Regulated Sirtuin 1 is Required for Smooth Muscle Cell Differentiation From Murine and Human Embryonic Stem Cells . CIRCULATION . vol. 128 ,

Zhou Y, Yan H, Guo M, Zhu J, Xiao Q, Zhang L ( 2013 ) . Reactive Oxygen Species in Vascular Formation and Development . Oxidative Medicine and Cellular Longevity vol. 2013 , 1 - 14 .

Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q et al. ( 2013 ) . XBP1 mRNA Splicing Triggers an Autophagic Response in Endothelial Cells through BECLIN-1 Transcriptional Activation . Journal of Biological Chemistry vol. 288 , ( 2 ) 859 - 872 .

Ali ZA, Rinze R, Antoniades C, Douglas G, Hu Y, Xiao Q, Greaves D, Alp N et al. ( 2012 ) . Abstract 18700: Accelerated Endothelial Regeneration and Survival Attenuate Vein Graft Atherosclerosis via Terahydrobiopterin-Dependent eNOS Coupling . Circulation vol. 126 , ( suppl_21 )

Tsai T-N, Kirton JP, Campagnolo P, Zhang L, Xiao Q, Zhang Z, Wang W, Hu Y et al. ( 2012 ) . Contribution of Stem Cells to Neointimal Formation of Decellularized Vessel Grafts in a Novel Mouse Model . The American Journal of Pathology vol. 181 , ( 1 ) 362 - 373 .

Motterle A, Pu X, Wood H, Xiao Q, Gor S, Liang Ng F, Chan K, Cross F et al. ( 2012 ) . Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells . Human Molecular Genetics vol. 21 , ( 18 ) 4021 - 4029 .

Zeng L, Xiao Q, Li H, Margariti A, Hu Y, Xu Q ( 2012 ) . XBP1 regulates endothelial growth and angiogenesis in ischemic tissues . Vascular Pharmacology . vol. 56 , 309 - 309 .

Xiao Q, Pepe AE, Wang G, Luo Z, Zhang L, Zeng L, Zhang Z, Hu Y et al. ( 2012 ) . Nrf3-Pla2g7 Interaction Plays an Essential Role in Smooth Muscle Differentiation From Stem Cells . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 32 , ( 3 ) 730 - 744 .

Xiao Q, Pepe AE, Wang G, Luo Z, Zhang L, Zeng L, Zhang Z, Hu Y et al. ( 2012 ) . Nrf3-Pla2g7 interaction plays an essential role in smooth muscle differentiation from stem cells . Arteriosclerosis Thrombosis and Vascular Biology vol. 32 , ( 3 ) 730 - 744 .

Liang Q-L, Liang X-P, Wang Y-M, Xie Y-Y, Zhang R-L, Chen X, Gao R, Cheng Y-J et al. ( 2012 ) . Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on \system to system\ mode . Journal of Translational Medicine vol. 10 , ( 1 ) Article 26 ,

Knoflach M, Kiechl S, Mantovani A, Cuccovillo I, Bottazzi B, Xu Q, Xiao Q, Gasperi A et al. ( 2012 ) . Pentraxin-3 as a Marker of Advanced Atherosclerosis Results from the Bruneck, ARMY and ARFY Studies . PLoS ONE vol. 7 , ( 2 ) e31474 - e31474 .

Motterle A, Xiao Q, Kiechl S, Pender SLF, Morris GE, Willeit J, Caulfield MJ, Ye S ( 2012 ) . Influence of matrix metalloproteinase-12 on fibrinogen level . Atherosclerosis vol. 220 , ( 2 ) 351 - 354 .

Wang G, Xiao Q, Luo Z, Ye S, Xu Q ( 2012 ) . Functional impact of heterogeneous nuclear ribonucleoprotein A2/B1 in smooth muscle differentiation from stem cells and embryonic arteriogenesis . Journal of Biological Chemistry vol. 287 , ( 4 ) 2896 - 2906 .

Xiao Q, Zhang F, Lin L, Fang C, Wen G, Tsai T-N, Pu X, Sims D et al. ( 2012 ) . A Functional Role of Matrix Metalloproteinase-8 in Stem/progenitor Cell Migration and Their Recruitment Into Atherosclerotic Lesions . CIRCULATION vol. 126 , ( 21 )

Wang G, Xiao Q, Luo Z, Ye S, Xu Q ( 2012 ) . Functional Impact of Heterogeneous Nuclear Ribonucleoprotein A2/B1 in Smooth Muscle Differentiation from Stem Cells and Embryonic Arteriogenesis . Journal of Biological Chemistry vol. 287 , ( 4 ) 2896 - 2906 .

Huang Y, Lin L, Yu X, Pu X, Zhu J, Zhang L, Ye S, Xiao Q ( 2012 ) . Functional Involvements of Heterogeneous Nuclear Ribonucleoprotein A1 in Smooth Muscle Differentiation from Stem Cells in vitro and in vivo . CIRCULATION vol. 126 , ( 21 )

Xiao Q, Zhang F, Grassia G, Hu Y, Zhang Z, Xing Q, Yin X, Maddaluno M et al. ( 2012 ) . Matrix Metalloproteinase-8 Promotes Vascular Smooth Muscle Cell Proliferation and Neointima Formation . CIRCULATION vol. 126 , ( 21 )

Luo Z, Wen G, Wang G, Pu X, Wang W, Ye S, Xu Q, Xiao Q ( 2012 ) . Microrna-200c and-150 Play a Role in Human Embryonic Stem Cell Differentiation Into Endothelial Cells and Blood Vessel Formation by Targeting Transcription Repressor Zebi . CIRCULATION vol. 126 , ( 21 )

Zhang L, Zheng X, Wu Y, Chen Q, Zhu J, Xiao Q ( 2012 ) . Microrna-34a Regulates Smooth Muscle Cell Differentiation from Stem Cells by 'Targeting Sirtnin 1 . CIRCULATION vol. 126 , ( 21 )

Sims D, Xiao Q ( 2011 ) . Smooth Muscle Cell Differentiation from Embryonic Stem Cells: Role of HDAC7 and PDGF-BB . Stem Cells and Cancer Stem Cells, Volume 4 , Springer Netherlands

Kiechl S, Paré G, Barbalic M, Qi L, Dupuis J, Dehghan A, Bis JC, Laxton RC et al. ( 2011 ) . Association of Variation at the\n <i>ABO</i>\n Locus With Circulating Levels of Soluble Intercellular Adhesion Molecule-1, Soluble P-selectin, and Soluble E-selectin . Circulation: Cardiovascular Genetics vol. 4 , ( 6 ) 681 - 686 .

Zhou B, Margariti A, Zeng L, Habi O, Xiao Q, Martin D, Wang G, Hu Y et al. ( 2011 ) . Splicing of Histone Deacetylase 7 Modulates Smooth Muscle Cell Proliferation and Neointima Formation Through Nuclear β-Catenin Translocation . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 31 , ( 11 ) 2676 - 2684 .

Xiao Q, Pepe A, Wang G, Luo Z, Zeng L, Ye S, Xu Q ( 2011 ) . PLA2G7 MEDIATES SMOOTH MUSCLE CELL DIFFERENTIATION FROM STEM CELLS . HEART . vol. 97 , 18 - 18 .

Wang G, Xiao Q, Xu Q ( 2011 ) . 4 Stem cell differentiation to smooth muscle cells is regulated by HnRNP A2/B1 . Heart vol. 97 , ( 20 ) e7 - e7 .

Luo Z, Xiao Q, Wang W, Xu Q ( 2011 ) . 6 Differentiation of human embryonic stem cells towards the endothelial lineage involves microRNAs . Heart vol. 97 , ( 20 ) e7 - e7 .

Xiao QZ, Wang G, Yin XK, Luo ZL, Margariti A, Zeng LF, Mayr M, Ye S et al. ( 2011 ) . Chromobox Protein Homolog 3 Is Essential for Stem Cell Differentiation to Smooth Muscles In Vitro and in Embryonic Arteriogenesis . ARTERIOSCL THROM VAS vol. 31 , ( 8 ) 1842 - U320 .

Kane NM, Xiao Q, Baker AH, Luo Z, Xu Q, Emanueli C ( 2011 ) . Pluripotent stem cell differentiation into vascular cells: A novel technology with promises for vascular re(generation) . Pharmacology &amp; Therapeutics vol. 129 , ( 1 ) 29 - 49 .

Luo Z ( 2011 ) . Signalling pathways that regulate endothelial differentiation from stem cells . Frontiers in Bioscience vol. 16 , ( 1 ) 472 - 472 .

Xiao QZ, Ye S ( 2011 ) . The genetics of epigenetics: is there a link with cardiovascular disease . HEART vol. 97 , ( 2 ) 96 - 97 .

Zhang L, Jin M, Margariti A, Wang G, Luo ZL, Zampetaki A, Zeng LF, Ye S et al. ( 2010 ) . Sp1-dependent Activation of HDAC7 Is Required for Platelet-derived Growth Factor-BB-induced Smooth Muscle Cell Differentiation from Stem Cells . J BIOL CHEM vol. 285 , ( 49 ) 38463 - 38472 .

Dotsenko O, Xiao Q, Xu Q, Jahangiri M ( 2010 ) . Bone Marrow Resident and Circulating Progenitor Cells in Patients Undergoing Cardiac Surgery . The Annals of Thoracic Surgery vol. 90 , ( 6 ) 1944 - 1951 .

Kiechl S, Laxton RC, Xiao QZ, Hernesniemi JA, Raitakari OT, Kahonen M, Mayosi BM, Jula A et al. ( 2010 ) . Coronary Artery Disease-Related Genetic Variant on Chromosome 10q11 Is Associated With Carotid Intima-Media Thickness and Atherosclerosis . ARTERIOSCL THROM VAS vol. 30 , ( 12 ) 2678 - U636 .

Xiao Q, Wang G, Bai X, Yin X, Luo Z, Mayr M, Ye S, Xu Q ( 2010 ) . BAS/BSCR30 Crucial roles of Cbx3 identified by nuclear proteomics in smooth muscle differentiation from stem cells and vascular injury-induced neointima formation . Heart vol. 96 , ( 17 ) e21 - e21 .

Zeng L, Xiao Q, Li H, Margariti A, Hu Y, Xu Q ( 2010 ) . BAS/BSCR43 X-box binding protein 1 splicing is crucial in endothelial cell proliferation . Heart vol. 96 , ( 17 ) e25 - e25 .

Margariti A, Zampetaki A, Xiao Q, Zhou B, Karamariti E, Martin D, Yin X, Mayr M et al. ( 2010 ) . Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of β-Catenin . Circulation Research vol. 106 , ( 7 ) 1202 - 1211 .

Pepe AE, Xiao Q, Zampetaki A, Zhang Z, Kobayashi A, Hu Y, Xu Q ( 2010 ) . Crucial Role of Nrf3 in Smooth Muscle Cell Differentiation From Stem Cells . Circulation Research vol. 106 , ( 5 ) 870 - 879 .

Ye S, Willeit J, Xiao QZ, Motterle A, Laxton RC, Oberhollenzer F, Kiechl S, Xu QB ( 2010 ) . Single nucleotide polymorphism on chromosome 9p21 and endothelial progenitor cells in a general population cohort . ATHEROSCLEROSIS vol. 208 , ( 2 ) 451 - 455 .

Laxton RC, Hu Y, Duchene J, Zhang F, Zhang Z, Leung KY, Xiao Q, Scotland RS et al. ( 2010 ) . A Role of Matrix Metalloproteinase-8 in Atherosclerosis (vol 105, pg 921, 2009) . CIRC RES vol. 106 , ( 1 ) E1 - E1 .

Zampetaki A, Zeng L, Margariti A, Xiao Q, Li H, Zhang Z, Pepe AE, Wang G et al. ( 2010 ) . Histone Deacetylase 3 Is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow . Circulation vol. 121 , ( 1 ) 132 - 142 .

Xiao Q, Pepe AE, Xu Q ( 2010 ) . Pla2g7 is Crucial in Stem Cell Differentiation into Smooth Muscle Cells and Involves in Atherosclerosis . CIRCULATION vol. 122 , ( 21 )

Zhang L, Hu Y, Zeng L, Xiao Q, Zhu J ( 2010 ) . Sp1-Dependent Activation of HDAC7 is Required for PDGF-BB-Induced Smooth Muscle Cell Differentiation From Stem Cells . CIRCULATION vol. 122 , ( 21 )

Margariti A, Li H, Martin D, Xiao Q, Zampetaki A, Hu Y, Xu Q, Zeng L ( 2010 ) . X-Box Binding Protein 1 Splicing Triggers an Autophagic Response-Mediated Survival in Endothelial Cells . CIRCULATION vol. 122 , ( 21 )

Zeng L, Xiao Q, Li H, Margariti A, Hu Y, Xu Q ( 2010 ) . Xbp1 Splicing is Crucial in Endothelial Cell Proliferation . CIRCULATION vol. 122 , ( 21 )

Xiao Q, Wang G, Bai X, Yin X, Mayr M, Wang X, Xu Q ( 2009 ) . Abstract 5444: Cbx3 Identified by Nuclear Proteomics Plays a Key Role in Stem Cell Differentiation Into Smooth Muscle Cells in vitro and in vivo . Circulation vol. 120 , ( suppl_18 )

Pepe AE, Xiao Q, Zampetaki A, Hu Y, Xu Q ( 2009 ) . Abstract 5474: Crucial Role of Nrf3 in Smooth Muscle Cell Differentiation From Stem Cells and Vessel Injury-Induced Neointima Formation . Circulation vol. 120 , ( suppl_18 )

Kiechl S, Laxton RC, Xiao Q, Willeit J, Xu Q, Ye S ( 2009 ) . CAD RELATED VARIATION ON CHROMOSOME 10q11 IS ASSOCIATED WITH CIRCULATING SDF-1ALPHA LEVEL AND CAROTID INTIMA-MEDIA THICKNESS AND ATHEROSCLEROSIS . Atherosclerosis . vol. 207 , e3 - e3 .

Laxton RC, Hu YH, Duchene J, Zhang F, Zhang ZY, Leung KY, Xiao QZ, Scotland RS et al. ( 2009 ) . A Role of Matrix Metalloproteinase-8 in Atherosclerosis . CIRC RES vol. 105 , ( 9 ) 921 - U231 .

Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N et al. ( 2009 ) . Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures . Blood vol. 114 , ( 3 ) 723 - 732 .

Dotsenko O, Xiao Q, Xu Q, Jahangiri M ( 2009 ) . Abstract: P224 SEVERITY OF CORONARY ATHEROSCLEROSIS AND CARDIOPULMONARY BYPASS AFFECT STEM CELL TRAFFICKING FOLLOWING CARDIAC SURGERY . Atherosclerosis Supplements vol. 10 , ( 2 ) e543 - e543 .

Zeng L, Zampetaki A, Margariti A, Pepe AE, Alam S, Martin D, Xiao Q, Wang W et al. ( 2009 ) . Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow . Proc Natl Acad Sci U S A. vol. 106 , ( 20 ) 8326 - 8331 .

Xiao Q, Xu Q ( 2009 ) . Caspase-8, a Double-Edged Sword for EPC Functioning . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 29 , ( 4 ) 444 - 446 .

Xiao Q, Luo Z, Pepe AE, Margariti A, Zeng L, Xu Q ( 2009 ) . Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H₂O₂ . American Journal of Physiology-Cell Physiology vol. 296 , ( 4 ) C711 - C723 .

Margariti A, Xiao Q, Zampetaki A, Zhang Z, Li H, Martin D, Hu Y, Zeng L et al. ( 2009 ) . Splicing of HDAC7 modulates the SRF-myocardin complex during stem-cell differentiation towards smooth muscle cells . J Cell Sci. vol. 122 , ( 4 ) 460 - 470 .

Pula G, Mayr U, Evans C, Prokopi M, Vara DS, Yin X, Astroulakis Z, Xiao Q et al. ( 2009 ) . Proteomics Identifies Thymidine Phosphorylase As a Key Regulator of the Angiogenic Potential of Colony-Forming Units and Endothelial Progenitor Cell Cultures . Circulation Research vol. 104 , ( 1 ) 32 - 40 .

Dotsenko O, Xiao Q, Xu Q, Jahangiri M ( 2009 ) . Altered trafficking of bone marrow-derived CXCR4+progenitor cells following cardiac surgery with the use of cardiopulmonary bypass . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 7 , 917 - 917 .

Xiao Q, Wang G, Bai X, Yin X, Mayr M, Wang X, Xu Q ( 2009 ) . Cbx3 Identified by Nuclear Proteomics Plays a Key Role in Stem Cell Differentiation Into Smooth Muscle Cells in vitro and in vivo . CIRCULATION . vol. 120 , S1093 - S1093 .

Pepe AE, Xiao Q, Zampetaki A, Hu Y, Xu Q ( 2009 ) . Crucial Role of Nrf3 in Smooth Muscle Cell Differentiation From Stem Cells and Vessel Injury-induced Neointima Formation . CIRCULATION . vol. 120 , S1098 - S1098 .

Dotsenko O, Xiao Q, Xu Q, Jahangiri M ( 2009 ) . Impaired Migration of Bone Marrow-Derived CXCR4<SUP>+</SUP> Progenitor Cells Following Cardiac Surgery with the Use of Cardiopulmonary Bypass . CIRCULATION RESEARCH . vol. 105 , E39 - E39 .

Xiao Q, Luo Z, Pepe A, Margariti A, Zeng L, Xu Q ( 2009 ) . NADPH OXIDASE PRODUCED HYDROGEN PEROXIDE-MEDIATED SMOOTH MUSCLE CELL DIFFERENTIATION FROM STEM CELL . HEART vol. 95 , ( 22 )

Pepe AE, Xiao Q, Zampetaki A, Xu Q ( 2009 ) . NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 3 MEDIATES STEM CELL DIFFERENTIATION INTO SMOOTH MUSCLE CELLS THROUGH INCREASED REACTIVE OXYGEN SPECIES GENERATION AND PLASMA PHOSPHOLIPASE A2 PRODUCTION . HEART vol. 95 , ( 22 )

Dotsenko O, Xiao Q, Xu Q, Jahangiri M ( 2009 ) . P4.12 EGRESS OF FUNCTIONALLY COMPETENT PROGENITOR CELLS OVER-EXPRESSING CXCR4 FROM THE BONE MARROW FOLLOWING CARDIAC SURGERY WITH THE USE OF CARDIOPULMONARY BYPASS . Artery Research vol. 3 , ( 4 ) 173 - 173 .

Prokopi M, Pula G, Mayr U, Boulanger CM, Xiao Q, Xu Q, Kiechl S, Mayr M ( 2009 ) . PROTEOMIC ANALYSIS REVEALS PRESENCE OF PLATELET MICROPARTICLES IN ENDOTHELIAL PROGENITOR CELL CULTURES . HEART vol. 95 , ( 22 )

Mayr U, Pula G, Evans C, Prokopi M, Yin X, Xiao Q, Hill J, Xu Q et al. ( 2009 ) . PROTEOMICS IDENTIFIES THYMIDINE PHOSPHORYLASE AS A KEY REGULATOR OF THE ANGIOGENIC POTENTIAL OF COLONY FORMING UNITS AND ENDOTHELIAL PROGENITOR CELL CULTURES . HEART vol. 95 , ( 22 )

Xiao Q, Savvidou MD, Nicolaides KH ( 2009 ) . Reply . American Journal of Obstetrics and Gynecology vol. 200 , ( 1 ) e19 - e20 .

Dotsenko O, Xiao Q, Xu Q, Jahangiri M ( 2009 ) . SEVERITY OF CORONARY ATHEROSCLEROSIS AND CARDIOPULMONARY BYPASS AFFECT STEM CELL TRAFFICKING FOLLOWING CARDIAC SURGERY . ATHEROSCLEROSIS SUPPLEMENTS vol. 10 , ( 2 )

Xiao QZ, Ye S, Oberhollenzer F, Mayr A, Jahangiri M, Willeit J, Kiechl S, Xu QB ( 2008 ) . SDF1 Gene Variation Is Associated with Circulating SDF1 alpha Level and Endothelial Progenitor Cell Number-The Bruneck Study . PLOS ONE vol. 3 , ( 12 ) Article e4061 ,

Xiao Q, Ye S, Oberhollenzer F, Mayr A, Jahangiri M, Willeit J, Kiechl S, Xu Q ( 2008 ) . SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study . PLoS One vol. 3 , ( 12 )

Margariti A, Xiao Q, Zampetaki A, Zhang Z, Li H, Hu Y, Zeng L, Xu Q ( 2008 ) . HISTONE DEACETYLASE 7 IS ESSENTIAL FOR STEM CELL DIFFERENTIATION INTO SMOOTH MUSCLE CELLS . Atherosclerosis . vol. 199 , 464 - 464 .

Hu Y, Foteinos G, Xiao Q, Xu Q ( 2008 ) . RAPID ENDOTHELIAL TURNOVER IN ATHEROSCLEROSIS-PRONE AREAS COINCIDES WITH STEM CELL REPAIR IN APOE-DEFICIENT MICE . Atherosclerosis . vol. 199 , 467 - 467 .

Zeng L, Zampetaki A, Margariti A, Li H, Zhang Z, Xiao Q, Hu Y, Xu Q ( 2008 ) . XBP1 IS A KEY PROTEIN INDUCING ENDOTHELIAL CELL DEATH IN VIVO AND IN VITRO . Atherosclerosis . vol. 199 , 465 - 466 .

Foteinos G, Hu Y, Xiao Q, Metzler B, Xu Q ( 2008 ) . Rapid Endothelial Turnover in Atherosclerosis-Prone Areas Coincides With Stem Cell Repair in Apolipoprotein E–Deficient Mice . Circulation vol. 117 , ( 14 ) 1856 - 1863 .

Foteinos G, Hu Y, Xiao Q, Metzler B, Xu Q ( 2008 ) . Rapid endothelial turnover in atherosclerosis-prone areas coincides with stem cell repair in apolipoprotein E-deficient mice . Circulation vol. 117 , ( 14 ) 1856 - 1863 .

Savvidou MD, Xiao Q, Kaihura C, Anderson JM, Nicolaides KH ( 2008 ) . Maternal circulating endothelial progenitor cells in normal singleton and twin pregnancy . American Journal of Obstetrics and Gynecology vol. 198 , ( 4 ) 414.e1 - 414.e5 .

Xiao Q, Zhang L, Luo Z, Pepe A, Margariti A, Zeng L, Xu Q ( 2008 ) . Nox4 is Crucial for Stem Cell Differentiation into Smooth Muscle Cells . CIRCULATION vol. 118 , ( 18 ) S411 - S411 .

Pula G, Mayr U, Evans C, Prokopi M, Xiao Q, Hill J, Xu Q, Mayr M ( 2008 ) . Proteomics Identifies Thymidine Phosphorylase as a Key Regulator of the Angiogenic Potential of Endothelial Progenitor Cells . CIRCULATION vol. 118 , ( 18 ) S412 - S412 .

Xiao Q, Ye S, Willeit J, Kiechl S, Xu Q ( 2008 ) . SDF-1/CXCR4 Gene Polymorphisms are Associated with Blood SDF-1α Proteins and Endothelial Progenitor Cells in Bruneck Population . CIRCULATION . vol. 118 , S1145 - S1145 .

Adams B, Xiao Q, Xu Q ( 2007 ) . Vascular Progenitor Cells and Atherosclerosis . Future Cardiology vol. 3 , ( 6 ) 635 - 645 .

Qi XW, Liu HF, Xue YZ, Kong XQ, Xu QB, Xiao QZ ( 2007 ) . Changes of endothelial progenitor cells and vascular endothelial growth factor in patients with coronary artery disease . Journal of Clinical Rehabilitative Tissue Engineering Research vol. 11 , ( 42 ) 8439 - 8443 .

Margariti A, Xiao Q, Zampetaki A, Hu Y, Zeng L, Xu Q ( 2007 ) . Abstract 433: HDAC7 is Essential for Stem Cell Differentiation into Smooth Muscle Cells . Circulation vol. 116 , ( suppl_16 )

Xiao Q, Kiechl S, Patel S, Oberhollenzer F, Weger S, Mayr A, Metzler B, Reindl M et al. ( 2007 ) . Endothelial Progenitor Cells, Cardiovascular Risk Factors, Cytokine Levels and Atherosclerosis – Results from a Large Population-Based Study . PLoS ONE vol. 2 , ( 10 ) e975 - e975 .

Sidibe A, Yin X, Tarelli E, Xiao Q, Zampetaki A, Xu Q, Mayr M ( 2007 ) . Integrated Membrane Protein Analysis of Mature and Embryonic Stem Cell-derived Smooth Muscle Cells Using a Novel Combination of CyDye/Biotin Labeling . Molecular &amp; Cellular Proteomics vol. 6 , ( 10 ) 1788 - 1797 .

Zampetaki A, Zeng L, Xiao Q, Margariti A, Hu Y, Xu Q ( 2007 ) . Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-α is rescued by HDAC inhibitor trichostatin A . American Journal of Physiology-Cell Physiology vol. 293 , ( 4 ) C1226 - C1238 .

Adams B, Xiao Q, Xu Q ( 2007 ) . Stem Cell Therapy for Vascular Disease . Trends in Cardiovascular Medicine vol. 17 , ( 7 ) 246 - 251 .

Xiao Q, Kiechl S, Patel S, Oberhollenzer F, Weger S, Mayr A, Metzler B, Reindl M et al. ( 2007 ) . Endothelial progenitor cells, cardiovascular risk factors, cytokines levels and atherosclerosis-results from a large population-based study . Atherosclerosis . vol. 193 , S5 - S5 .

Roberts N, Xiao Q, Weir G, Xu Q, Jahangiri M ( 2007 ) . Endothelial Progenitor Cells are Mobilized After Cardiac Surgery . The Annals of Thoracic Surgery vol. 83 , ( 2 ) 598 - 605 .

Xiao Q, Zeng L, Zhang Z, Hu Y, Xu Q ( 2007 ) . Stem cell-derived Sca-1⁺ progenitors differentiate into smooth muscle cells, which is mediated by collagen IV-integrin α₁/β₁/α_v and PDGF receptor pathways . American Journal of Physiology-Cell Physiology vol. 292 , ( 1 ) C342 - C352 .

Yin X, Mayr M, Xiao Q, Wang W, Xu Q ( 2006 ) . Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells . PROTEOMICS vol. 6 , ( 24 ) 6437 - 6446 .

Xiao Q, Zeng L, Zhang Z, Margariti A, Ali ZA, Channon KM, Xu Q, Hu Y ( 2006 ) . Sca-1\n ⁺\n Progenitors Derived From Embryonic Stem Cells Differentiate Into Endothelial Cells Capable of Vascular Repair After Arterial Injury . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 26 , ( 10 ) 2244 - 2251 .

Zeng L, Xiao Q, Margariti A, Zhang Z, Zampetaki A, Patel S, Capogrossi MC, Hu Y et al. ( 2006 ) . HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells . The Journal of Cell Biology vol. 174 , ( 7 ) 1059 - 1069 .

Yin X, Xiao Q, Mayr U, Mayr M, Xu Q ( 2006 ) . Proteomic analysis of embryonic stem cell-derived smooth muscle cells . Vascular Pharmacology vol. 45 , ( 3 ) e72 - e72 .

Zeng L, Xiao Q, Margariti A, Xu Q ( 2006 ) . Shear stress-induced stem cell differentiation toward endothelial cells is regulated by HDAC-P53-P21 pathways . Vascular Pharmacology vol. 45 , ( 3 ) e52 - e52 .

Zampetaki A, Xiao Q, Zeng L, Xu Q ( 2006 ) . TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications . Vascular Pharmacology vol. 45 , ( 3 ) e12 - e12 .

Zampetaki A, Xiao Q, Zeng L, Hu Y, Xu Q ( 2006 ) . TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications . Biochemical and Biophysical Research Communications vol. 347 , ( 1 ) 89 - 99 .

Xiao Q, Mandal K, Schett G, Mayr M, Wick G, Oberhollenzer F, Willeit J, Kiechl S et al. ( 2005 ) . Association of Serum-Soluble Heat Shock Protein 60 With Carotid Atherosclerosis . Stroke vol. 36 , ( 12 ) 2571 - 2576 .

Yin XK, Mayr M, Xiao QZ, Mayr U, Tarelli E, Wait R, Wang W, Xu QB ( 2005 ) . Proteomic dataset of Sca-1(+) progenitor cells . PROTEOMICS vol. 5 , ( 17 ) 4533 - 4545 .

Dong XX, Liu JB, Dong YX, He HH, Dong WH, Liang ZP, Xiao QZ ( 2005 ) . Chinese herbs for inducing differentiation of mesenchymal stem cells in rats . Chinese Journal of Clinical Rehabilitation vol. 9 , ( 9 ) 210 - 212 .

Xiao QZ, Su DH, Jiang JH, Zhong NS ( 2005 ) . Distribution and drug-resistance of 3 500 gram-negative bacteria in Guangzhou . Di 1 Jun Yi Da Xue Xue Bao Academic Journal of the First Medical College of PLA vol. 25 , ( 2 ) 132 - 138 .

Tang Y, Wu J, Sun X, Li W, He T, Yin S, Liu L, Chen Y et al. . Cardiolipin Oxidized&amp;nbsp;By Complex II Acts a Target of Gasdermin D&amp;nbsp;to Drive Mitochondrial Apoptotic&amp;nbsp;Pore&amp;nbsp;Forming and Heart&amp;nbsp;Dysfunction in Endotoxemia .