Publications: DR Rosalind Hannen

McPolin-Hall E, Stephen A, Pardieu C, Allaker R, Philpott M, Bhogal R, Pople J, Hannen R ( 2023 ) . O06 Exploring host–microbiome–immune interactions using singular and multispecies inoculations in optimized 3D skin models . British Journal of Dermatology vol. 189 , ( 1 ) e6 - e6 .

Uddin N, Ostano P, Chiorino G, di Domizio J, Gilliet M, Philpott M, Hannen R, Bergamaschi D ( 2023 ) . O09 Dynamic impact of chronic inflammation on epidermal autophagy pathway . British Journal of Dermatology vol. 189 , ( 1 ) e7 - e8 .

McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J, Hannen R ( 2023 ) . 910 Exploring host-microbiome interactions in optimised 3D skin models . Journal of Investigative Dermatology vol. 143 , ( 5 )

( 2023 ) . Chapter 15 Skin tissue engineering and keratinocyte stem cell therapy . Tissue Engineering , Elsevier

McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J, Hannen R ( 2022 ) . 200 Optimised 3D skin models incorporating microbiome and host immune responses . Journal of Investigative Dermatology vol. 142 , ( 12 )

Lawrence K, Kung C, Ahmed Z, Bashall S, Brand S, Frame J, Philpott M, Castrejon-Pita R et al. ( 2022 ) . 222 Enhanced Environmental Control Resolves Limitations of Standard Skin Culture by Mimicking Physiological Conditions . Journal of Investigative Dermatology vol. 142 , ( 12 )

Kung C, Lawrence K, Ahmed Z, McPolin-Hall E, Barnard I, Brand S, Frame J, Philpott M et al. ( 2022 ) . 233 A novel ex vivo skin culture device enables clinically representative skin testing . Journal of Investigative Dermatology vol. 142 , ( 12 )

Uddin N, Ostano P, Chiorino G, Philpott M, Hannen R, Bergamaschi D ( 2022 ) . 347 Chronic Inflammation of Keratinocytes Leads to Autophagy Impairment in Psoriasis . Journal of Investigative Dermatology vol. 142 , ( 12 )

Begum Uddin N, Ostano P, Chiorino G, Philpott M, Hannen R, Bergamaschi D ( 2022 ) . ESDR347 - Chronic Inflammation of Keratinocytes Leads to Autophagy Impairment in Psoriasis .

McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J, Hannen R ( 2022 ) . ESDR200 - Optimised 3D skin models incorporating microbiome and host immune responses .

Kung C-P, Lawrence K, Ahmed Z, McPolin-Hall E, Barnard I, Brand S, Frame J, Philpott M et al. ( 2022 ) . ESDR233 - A novel ex vivo skin culture device enables clinically representative skin testing .

Hannen R, Connelly J, Myers S ( 2022 ) . Skin tissue engineering and keratinocyte stem cell therapy . Tissue Engineering Third Edition ,

Jacob J, Nadkarni S, Peng Q, Tung SL, Hannen RF, Mohseni YR, Scotta C, Marelli-Berg FM et al. ( 2020 ) . Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment . Molecular Therapy — Methods & Clinical Development vol. 20 , 324 - 336 .

Evans EA, Sayers SR, Kodji X, Xia Y, Shaikh M, Rizvi A, Frame J, Brain SD et al. ( 2020 ) . Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome . Molecular Metabolism vol. 41 ,

( 2020 ) . Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage . Frontiers in Cell and Developmental Biology vol. 8 ,

Evans E, Brain S, Philpott M, Caton P, Hannen R ( 2018 ) . 1005 The skin: A new player in the control of whole-body glucose homeostasis . Journal of Investigative Dermatology vol. 138 , ( 5 )

Hannen R, Leigh I, Philpott M ( 2018 ) . 717 Dysfunctional stress response in psoriatic keratinocytes . Journal of Investigative Dermatology . vol. 138 ,

Caton PW, Evans EA, Philpott MP, Hannen RF ( 2017 ) . Can the skin make you fat? A role for the skin in regulating adipose tissue function and whole-body glucose and lipid homeostasis . Current Opinion in Pharmacology vol. 37 , 59 - 64 .

Hannen RF, Asher S, Mannella V, Purdie K, Leigh I, Philpott M ( 2017 ) . 131 Stressed out keratinocytes, new insights into psoriasis lesion formation . Journal of Investigative Dermatology . vol. 137 ,

Halim L, Romano M, McGregor R, Correa I, Pavlidis P, Grageda N, Hoong S-J, Yuksel M et al. ( 2017 ) . An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment . Cell Reports vol. 20 , ( 3 ) 757 - 770 .

Hannen R, Udeh-Momoh C, Upton J, Wright M, Michael A, Gulati A, Rajpopat S, Clayton N et al. ( 2017 ) . Dysfunctional Skin-Derived Glucocorticoid Synthesis Is a Pathogenic Mechanism of Psoriasis . Journal of Investigative Dermatology vol. 137 , ( 8 ) 1630 - 1637 .

Evans EA, Sayers SR, Philpott MP, Hannen RF, Caton PW ( 2017 ) . A novel skin-adipose tissue axis regulates pancreatic beta cell function . vol. 34 , is. Special Issue 1 , pp. 42 - 42 .

Boardman DA, Philippeos C, Fruhwirth GO, Ibrahim MAA, Hannen RF, Cooper D, Marelli-Berg FM, Watt FM et al. ( 2017 ) . Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection . American Journal of Transplantation vol. 17 , ( 4 ) 931 - 943 .

Hannen RF, Perez P, Lightman S, Philpott MP ( 2016 ) . Stabilising the Glucocorticoid Response in Psoriatic Skin . vol. 175 , pp. 45 - 45 .

Upton JH, Hannen RF, Bahta AW, Farjo N, Farjo B, Philpott MP ( 2015 ) . Oxidative Stress–Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia . Journal of Investigative Dermatology vol. 135 , ( 5 ) 1244 - 1252 .

Hannen RF, Michael AE, Jaulim A, Bhogal R, Burrin JM, Philpott MP ( 2011 ) . Steroid synthesis by primary human keratinocytes; implications for skin disease . Biochem Biophys Res Commun vol. 404 , ( 1 ) 62 - 67 .

( 2008 ) . Hyperglycaemic patients have decreased ATP-binding cassette transporter-A1 (ABCA-1) gene expression: A novel disease mechanism . Atherosclerosis vol. 199 , ( 1 ) 231 - 232 .

Hannen RF, Michael AE, Burrin J, Philpott M ( 2008 ) . Cortisol synthesis and regulation of proliferation in keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 128 , S139 - S139 .

Hannen RF, Michael AE, Burrin J, Philpott MP ( 2008 ) . StAR role for glucocorticoid synthesis in keratinocytes . BRITISH JOURNAL OF DERMATOLOGY . vol. 158 , 881 - 881 .

Hannen RF, Michael AE, Burrin JM, Philpott M ( 2007 ) . Human skin and keratinocytes express cholesterol transporters and primary keratinocytes are capable of metabolising progesterone into cortisol . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 127 , S60 - S60 .

. A Biological Culture Unit .

. Imaging Device Adaptor .

McPolin-Hall EP, Stephen AS, Pardieu C, Georgeu G, Allaker RP, Bhogal RK, Pople JE, Philpott MP et al. . Microbially-competent skin organotypics reveal dysregulated AhR signalling in microbial dysbiosis .

. Skin culturing apparatus and method .