Publications: DR Sarah Finer
(
2026
)
.
Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases
.
Nature Genetics
vol.
58
,
(
2
)
307
-
316
.
(
2026
)
.
Large-Scale Proteomic Profiling of Incident Heart Failure and Its Subtypes in Older Adults
.
Circulation Genomic and Precision Medicine
vol.
19
,
(
1
)
Constantinides M, Gafton J, Garcia ACA, Dixon PH, Williamson C, Linton K, Finer S, Gill US et al.
(
2025
)
.
A genes and health recall study of intrahepatic cholestasis of pregnancy and cholestatic liver disease
.
Communications Medicine
vol.
5
,
(
1
)
Small AM, Yang T-Y, Itoh S, Thériault S, Dufresne L, Kurosawa R, Komuro I, Matsuda K et al.
(
2025
)
.
Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction
.
Nature Genetics
vol.
58
,
(
1
)
57
-
66
.
Tsang RSM, Stow D, Kwong ASF, Donnelly NA, Fraser H, Barroso I, Holmans PA, Owen MJ et al.
(
2025
)
.
Immunometabolic blood biomarkers of developmental trajectories of depressive symptoms: findings from the ALSPAC birth cohort
.
Molecular Psychiatry1
-
11
.
(
2025
)
.
Genetics of Cholesterol and Coronary Disease Risk across Six Global Ancestries
.
NEJM Evidence
vol.
4
,
(
11
)
evidoa2500105
-
evidoa2500105
.
Martin S, Samuel M, Stow D, Ridsdale AM, Chen J, Young KG, Green HD, Hattersley AT et al.
(
2025
)
.
Undiagnosed G6PD deficiency in Black and Asian individuals is prevalent and contributes to health inequalities in type 2 diabetes diagnosis and complications
.
Diabetes Care
vol.
48
,
(
11
)
1932
-
1941
.
Wolford BN, Zhao QY, Wu K-HH, Yu X, Richter CE, Bhatta L, Brumpton BM, Desch KC et al.
(
2025
)
.
Multipopulation GWAS for venous thromboembolism identifies novel loci followed by experimental validation in zebrafish
.
Blood Advances
vol.
9
,
(
19
)
4850
-
4859
.
Siddiqui MK, Dupuis T, Anjana RM, Dawed AY, Bigossi M, Srinivasan S, Hodgson S, Adedire ET et al.
(
2025
)
.
XBP1 expression in pancreatic islet cells is associated with poor glycaemic control especially in young non-obese onset diabetes across ancestries
.
Communications Medicine
vol.
5
,
(
1
)
Orazumbekova B, Hamdani T, Hodgson S, Samuel M, Stow D, Spreckley M, Finer S, Siddiqui MK et al.
(
2025
)
.
Evidence of ethnic variations in the relationships between routinely recorded clinical factors and T2D: a systematic review and meta-analysis
.
International Journal of Obesity
vol.
49
,
(
10
)
1929
-
1945
.
Du-Harpur X, Maxwell J, Mitchell BL, Pardo LM, Witkam WCAM, Dand N, Bartels M, Betti M et al.
(
2025
)
.
O10 Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity
.
British Journal of Dermatology
vol.
193
,
(
Supplement_1
)
VORA M, LI J, HIANG HENG T, HUERTA A, SASO-JIMÉNEZ L, MANDLA R, MANNING A, CAREY DJ et al.
(
2025
)
.
73-OR: Large-Scale Multiancestry Recessive GWAS Meta-analysis Identifies Novel Recessive Associations and Improves Polygenic Prediction of Type 2 Diabetes
.
Diabetes
vol.
74
,
(
Supplement_1
)
Heng TH, Walter K, Huang QQ, Karjalainen J, Daly MJ, Heyne HO, FinnGen, Malawsky DS et al.
(
2025
)
.
Widespread recessive effects on common diseases in a cohort of 44,000 British Pakistanis and Bangladeshis with high autozygosity
.
American Journal of Human Genetics
vol.
112
,
(
6
)
1316
-
1329
.
(
2025
)
.
Inherited predisposition to pneumothorax: estimating the frequency of Birt-Hogg-Dubé syndrome from genomics and population cohorts
.
Thorax
vol.
80
,
(
8
)
553
-
555
.
Law JH, Stow D, Hodgson S, Team GHR, van Heel DA, Newman WG, Osman M, Finer S
(
2025
)
.
Perceived risk of type 2 diabetes: Using linked genomic, clinical and questionnaire data to understand the potential use of genetic risk tools in British South Asians
.
PLOS Global Public Health
vol.
5
,
(
3
)
Henry A, Mo X, Finan C, Chaffin MD, Speed D, Issa H, Denaxas S, Ware JS et al.
(
2025
)
.
Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes
.
Nature Genetics
vol.
57
,
(
4
)
815
-
828
.
(
2025
)
.
Understanding the potential contribution of polygenic risk scores to the prediction of gestational and type 2 diabetes in women from British Pakistani and Bangladeshi groups: a cohort study in Genes and Health
.
AJOG Global Reports
vol.
5
,
(
2
)
100457
-
100457
.
Consortium MDDWGOTPG, Adams MJ, Streit F, Meng X, Awasthi S, Adey BN, Choi KW, Chundru VK et al.
(
2025
)
.
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies
.
Cell
vol.
188
,
(
3
)
640
-
652.e9
.
Hodgson S, Williamson A, Bigossi M, Stow D, Jacobs BM, Samuel M, Gafton J, Zöllner J et al.
(
2024
)
.
Genetic basis of early onset and progression of type 2 diabetes in South Asians
.
Nature Medicine
vol.
31
,
(
1
)
323
-
331
.
Hamilton F, Schurz H, Yates TA, Gilchrist JJ, Möller M, Naranbhai V, Ghazal P, Timpson NJ et al.
(
2024
)
.
Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study
.
The Lancet Microbe
vol.
6
,
(
1
)
Jacobs BM, Stow D, Hodgson S, Zöllner J, Samuel M, Kanoni S, Bidi S, Walter K et al.
(
2024
)
.
Genetic architecture of routinely acquired blood tests in a British South Asian cohort
.
Nature Communications
vol.
15
,
(
1
)
Gomez EA, De Matteis R, Udomjarumanee P, Team GAHR, Akhtar S, Anwar M, Arciero E, Asgar O et al.
(
2024
)
.
An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections
.
Blood
vol.
144
,
(
4
)
420
-
434
.
Samuel M, Park RY, Eastwood SV, Eto F, Morton CE, Stow D, Bacon S, Mehrkar A et al.
(
2024
)
.
Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform
.
PLOS Medicine
vol.
21
,
(
6
)
Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A et al.
(
2024
)
.
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
.
Nature
vol.
627
,
(
8003
)
347
-
357
.
Samuel M, Park RY, Eastwood SV, Eto F, Morton CE, Stow D, Bacon S, Goldacre B et al.
(
2024
)
.
Weight trends amongst adults with diabetes or hypertension during the COVID-19 pandemic: an observational study using OpenSAFELY
.
British Journal of General Practice
vol.
74
,
(
748
)
Calderón-Larrañaga S, Greenhalgh T, Finer S, Clinch M
(
2024
)
.
What does social prescribing look like in practice? A qualitative case study informed by practice theory
.
Social Science & Medicine
vol.
343
,
Meng X, Navoly G, Giannakopoulou O, Levey DF, Koller D, Pathak GA, Koen N, Lin K et al.
(
2024
)
.
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
.
Nature Genetics
vol.
56
,
(
2
)
222
-
233
.
Ahmad TA, Dayem Ullah AZ, Chelala C, Gopal DP, Eto F, Henkin R, Samuel M, Finer S et al.
(
2024
)
.
Prevalence of multimorbidity in survivors of 28 cancer sites: an English nationwide cross-sectional study
.
American Journal of Cancer Research
vol.
14
,
(
2
)
880
-
896
.
Law JH, Sultan N, Finer S, Fudge N
(
2023
)
.
Advancing the communication of genetic risk for cardiometabolic diseases: a critical interpretive synthesis
.
BMC Medicine
vol.
21
,
(
1
)
Magavern EF, Jacobs B, Warren H, Finocchiaro G, Finer S, Van Heel DA, Smedley D, Caulfield MJ
(
2023
)
.
CYP2C19 genotype prevalence and association with recurrent myocardial infarction in British-South Asians treated with clopidogrel
.
European Heart Journal
vol.
44
,
(
Supplement_2
)
Eto F, Samuel M, Henkin R, Mahesh M, Ahmad T, Angdembe A, McAllister-Williams RH, Missier P et al.
(
2023
)
.
Ethnic differences in early onset multimorbidity and associations with health service use, long-term prescribing, years of life lost, and mortality: A cross-sectional study using clustering in the UK Clinical Practice Research Datalink
.
PLOS Medicine
vol.
20
,
(
10
)
Malawsky DS, van Walree E, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM et al.
(
2023
)
.
Influence of autozygosity on common disease risk across the phenotypic spectrum
.
Cell
vol.
186
,
(
21
)
4514
-
4527.e14
.
Kanai M, Andrews SJ, Cordioli M, Stevens C, Neale BM, Daly M, Ganna A, Chwialkowska K et al.
(
2023
)
.
A second update on mapping the human genetic architecture of COVID-19
.
Nature
vol.
621
,
(
7977
)
e7
-
e26
.
Magavern EF, Jacobs B, Warren H, Finocchiaro G, Finer S, van Heel DA, Team GHR, Smedley D et al.
(
2023
)
.
CYP2C19 Genotype Prevalence and Association With Recurrent Myocardial Infarction in British–South Asians Treated With Clopidogrel
.
JACC Advances
vol.
2
,
(
7
)
Zöllner J, Finer S, Linton KJ, van Heel DA, Williamson C, Dixon PH
(
2023
)
.
Rare variant contribution to cholestatic liver disease in a South Asian population in the United Kingdom
.
Scientific Reports
vol.
13
,
(
1
)
Law JH, Sultan N, Finer S, Fudge N
(
2023
)
.
Advancing the communication of genetic risk for cardiometabolic diseases: A critical interpretive synthesis
.
Burley K, Fitzgibbon L, van Heel D, Team GHR, Akhtar S, Anwar M, Arciero E, Asgar O et al.
(
2023
)
.
PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry
.
Research and Practice in Thrombosis and Haemostasis
vol.
7
,
(
4
)
Dambha-Miller H, Farmer A, Nirantharakumar K, Jackson T, Yau C, Walker L, Buchan I, Finer S et al.
(
2023
)
.
<p>Artificial Intelligence for Multiple Long-term conditions (AIM): A consensus statement from the NIHR AIM consortia</p>
.
NIHR Open Research
vol.
3
,
Calderón-Larrañaga S, Greenhalgh T, Clinch M, Robson J, Dostal I, Eto F, Finer S
(
2023
)
.
Unravelling the potential of social prescribing in individual-level type 2 diabetes prevention: a mixed-methods realist evaluation
.
BMC Medicine
vol.
21
,
(
1
)
Dobson R, Jacobs B, Marshall C
(
2023
)
.
Polygenic risk score prediction of Multiple Sclerosis in individuals of South Asian ancestry
.
Brain Communications
Wang Y, Namba S, Lopera E, Kerminen S, Tsuo K, Läll K, Kanai M, Zhou W et al.
(
2023
)
.
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts
.
Cell Genomics
vol.
3
,
(
1
)
Law JH, Sultan N, Finer S, Fudge N
(
2023
)
.
Cognitive factors and the appraisal of risk in cardiometabolic diseases: A critical interpretive synthesis of existing evidence to guide enhanced genetic risk communication
.
DIABETIC MEDICINE
.
vol.
40
,
Paterson GG, Liu T, Sankareswaran A, Chandak GR, Thomas NJ, Weedon MN, Yajnik CS, Oram R et al.
(
2023
)
.
Estimating the prevalence of type 1 and type 2 diabetes in British Bangladeshis and Pakistanis with an ambiguous diabetes phenotype using polygenic risk scores
.
DIABETIC MEDICINE
.
vol.
40
,
Calderon-Larranaga S, Greenhalgh T, Clinch M, Eto F, Robson J, Dostal I, Finer S
(
2023
)
.
Unravelling the potential of social prescribing in type 2 diabetes prevention: A mixed methods realist evaluation
.
DIABETIC MEDICINE
.
vol.
40
,
Kremer R, Raza SM, Eto F, Casement J, Atallah C, Finer S, Lendrem D, Barnes M et al.
(
2022
)
.
Tracking trajectories of multiple long-term conditions using dynamic patient-cluster associations
.
Conference:
2022 IEEE International Conference on Big Data (Big Data)
vol.
00
,
4390
-
4399
.
Papoutsi C, Hargreaves D, Hagell A, Hounsome N, Skirrow H, Muralidhara K, Colligan G, Ferrey A et al.
(
2022
)
.
Implementation and delivery of group consultations for young people with diabetes in socioeconomically deprived, ethnically diverse settings
.
BMC Medicine
vol.
20
,
(
1
)
Kanai M, Elzur R, Zhou W, Initiative GBM-A, Zhou W, Kanai M, Wu K-HH, Rasheed H et al.
(
2022
)
.
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution
.
Cell Genomics
vol.
2
,
(
12
)
Zhou W, Kanai M, Wu K-HH, Rasheed H, Tsuo K, Hirbo JB, Wang Y, Bhattacharya A et al.
(
2022
)
.
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
.
Cell Genomics
vol.
2
,
(
10
)
BYH L, A W, S F, FR D, JA T, Soares AG, K W, P S et al.
(
2022
)
.
MC3R links nutritional state to childhood growth and the timing of puberty
.
Huang QQ, Sallah N, Dunca D, Trivedi B, Hunt KA, Hodgson S, Lambert SA, Arciero E et al.
(
2022
)
.
Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals
.
Nature Communications
vol.
13
,
(
1
)
Nguyen H, Solomonson M, Palotie A, Davis L, Lee S, Priest J, Sankaran VG, van Heel D et al.
(
2022
)
.
A first update on mapping the human genetic architecture of COVID-19
.
Nature
vol.
608
,
(
7921
)
e1
-
e10
.
Papoutsi C, Hargreaves D, Hagell A, Hounsome N, Skirrow H, Muralidhara K, Colligan G, Vijayaraghavan S et al.
(
2022
)
.
Group clinics for young adults living with diabetes in an ethnically diverse, socioeconomically deprived population: mixed-methods evaluation
.
Health and Social Care Delivery Research
vol.
10
,
(
25
)
1
-
124
.
Hodgson S, Huang QQ, Sallah N, Team GHR, Griffiths CJ, Newman WG, Trembath RC, Wright J et al.
(
2022
)
.
Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study
.
PLOS Medicine
vol.
19
,
(
5
)
Calderón‐Larrañaga S, Greenhalgh T, Finer S, Clinch M
(
2022
)
.
What does the literature mean by social prescribing? A critical review using discourse analysis
.
Sociology of Health & Illness
vol.
44
,
(
4-5
)
848
-
868
.
Baillie JK, Begg C, Clohisey Hendry S, Hinds C, Horby P, Knight J, Ling L, Maslove D et al.
(
2022
)
.
Whole-genome sequencing reveals host factors underlying critical COVID-19
.
Nature
vol.
607
,
(
7917
)
97
-
103
.
Pervjakova N, Moen G-H, Borges M-C, Ferreira T, Cook JP, Allard C, Beaumont RN, Canouil M et al.
(
2022
)
.
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
.
Human Molecular Genetics
vol.
31
,
(
19
)
3377
-
3391
.
Mathur R, Hull SA, Hodgson S, Finer S
(
2022
)
.
Characterisation of type 2 diabetes subgroups and their association with ethnicity and clinical outcomes: a UK real-world data study using the East London Database
.
British Journal of General Practice
vol.
72
,
(
719
)
Nongmaithem SS, Beaumont RN, Dedaniya A, Wood AR, Ogunkolade B-W, Hassan Z, Krishnaveni GV, Kumaran K et al.
(
2022
)
.
Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns
.
Diabetes
vol.
71
,
(
4
)
821
-
836
.
Ogunkolade BW, Adaikalakoteswari A, Cardoso SR, Lowe R, Patel N, Rakyan V, Finer S, Wabitsch M et al.
(
2022
)
.
An integrative epi-transcriptomic approach identifies the human cartilage chitinase 3-like protein 2 (CHI3L2) as a potential mediator of B12 deficiency in adipocytes
.
Epigenetics
Hodgson S, Huang QQ, Sallah N, Lumbers RT, Kuchenbaecker K, van Heel DA, Mathur R, Griffiths CJ et al.
(
2022
)
.
A type 2 diabetes polygenic risk score enhances prediction of incident diabetes compared to QDiabetes alone in British Pakistani and Bangladeshis: Results from the Genes and Health study
.
DIABETIC MEDICINE
.
vol.
39
,
Calderon-Larranaga S, Clinch M, Finer S
(
2022
)
.
Social prescribing: A new partner for the NHS Diabetes Prevention Programme?
.
DIABETIC MEDICINE
.
vol.
39
,
Lau EYM, Carroll E, Callender L, Finer S, Henson S
(
2022
)
.
The impact of type 2 diabetes on immunosenescence and functional immunity
.
CLINICAL AND EXPERIMENTAL ALLERGY
.
vol.
52
,
1037
-
1037
.
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al.
(
2021
)
.
Risk Factors for Developing COVID-19: A Population-Based Longitudinal Study (COVIDENCE UK)
.
Thorax
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young KS, Davies MR et al.
(
2021
)
.
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
.
Thorax
vol.
77
,
(
9
)
900
-
912
.
Sobczyńska-Malefora A, Yajnik CS, Harrington DJ, Hitman GA, Finer S
(
2021
)
.
Vitamin B12 and Folate Markers Are Associated with Insulin Resistance During the Third Trimester of Pregnancy in South Asian Women, Living in the United Kingdom, with Gestational Diabetes and Normal Glucose Tolerance
.
Journal of Nutrition
vol.
152
,
(
1
)
163
-
170
.
Lam BYH, Williamson A, Finer S, Day FR, Tadross JA, Gonçalves Soares A, Wade K, Sweeney P et al.
(
2021
)
.
MC3R links nutritional state to childhood growth and the timing of puberty
.
Nature
vol.
599
,
(
7885
)
436
-
441
.
D’Antonio M, Nguyen JP, Arthur TD, Matsui H, Neale BM, Daly M, Ganna A, Stevens C et al.
(
2021
)
.
SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues
.
Cell Reports
vol.
37
,
(
7
)
Callender L, Carroll E, Ketchley-Garrod C, Schroth J, BYSTROM J, Berryman V, Pattrick M, Campbell-Richards D et al.
(
2021
)
.
Altered nutrient uptake causes mitochondrial dysfunction in senescent CD8+ EMRA T cells during type 2 diabetes
.
Frontiers in Aging
van Blokland IV, Lanting P, Ori APS, Vonk JM, Warmerdam RCA, Herkert JC, Boulogne F, Claringbould A et al.
(
2021
)
.
Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility
.
PLOS ONE
vol.
16
,
(
8
)
Edwards AE, Vathenen R, Henson SM, Finer S, Gunganah K
(
2021
)
.
Acute hyperglycaemic crisis after vaccination against COVID‐19: A case series
.
Diabetic Medicine
vol.
38
,
(
11
)
Niemi MEK, Karjalainen J, Liao RG, Neale BM, Daly M, Ganna A, Davis L, Lee S et al.
(
2021
)
.
Mapping the human genetic architecture of COVID-19
.
Nature
vol.
600
,
(
7889
)
472
-
477
.
Calderón-Larrañaga S, Milner Y, Clinch M, Greenhalgh T, Finer S
(
2021
)
.
Tensions and opportunities in social prescribing. developing a framework to facilitate its implementation and evaluation in primary care: a realist review
.
BJGP Open
vol.
5
,
(
3
)
Calderón-Larrañaga S, Clinch M, Greenhalgh T, Finer S
(
2021
)
.
Could social prescribing contribute to type 2 diabetes prevention in people at high risk? Protocol for a realist, multilevel, mixed methods review and evaluation
.
BMJ Open
vol.
11
,
(
4
)
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al.
(
2021
)
.
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
.
MedRvx
Papoutsi C, Hargreaves D, Colligan G, Hagell A, MacKinnon S, Vijayaraghavan S, Greenhalgh T, Finer S
(
2020
)
.
G416 Sociodemographic and clinical predictors of attendance at group clinics for young adults with diabetes (together study)
.
Conference:
BSPEDa150.1
-
a1a150
.
Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J et al.
(
2020
)
.
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
.
N Engl J Med
vol.
383
,
(
16
)
1522
-
1534
.
Saravanan P, Group DIPW, Group MMCS, College of Obstetricians and Gynaecologists, Magee LA, Banerjee A, Coleman MA, Von Dadelszen P et al.
(
2020
)
.
Gestational diabetes: opportunities for improving maternal and child health
.
The Lancet Diabetes & Endocrinology
vol.
8
,
(
9
)
793
-
800
.
McGregor TL, Hunt KA, Yee E, Mason D, Nioi P, Ticau S, Pelosi M, Loken PR et al.
(
2020
)
.
Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria
.
eLife
vol.
9
,
Finer S, Martin HC, Khan A, Hunt KA, MacLaughlin B, Ahmed Z, Ashcroft R, Durham C et al.
(
2019
)
.
Cohort Profile: East London Genes & Health (ELGH), a community-based population genomics and health study in British Bangladeshi and British Pakistani people
.
International Journal of Epidemiology
vol.
49
,
(
1
)
20
-
21i
.
Ong SE, Clinch M, Mathur R, Perel P, Chia KS, Legido-Quigley H, Finer S
.
Improving Type 2 Diabetes prevention and care in England – what can healthcare transformation achieve?: A qualitative study
.
International Journal of Integrated Care
.
vol.
19
,
Lau EYM, Carroll EC, Callender LA, Hood GA, Berryman V, Pattrick M, Finer S, Hitman GA et al.
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Type 2 diabetes is associated with the accumulation of senescent T cells
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Clinical & Experimental Immunology
Papoutsi C, COLLIGAN G, Hagell A, Hargreaves D, Marshall M, VIJAYARAGHAVAN S, Greenhalgh T, FINER S
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Promises and perils of group clinics for young people living with diabetes: a realist review
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Finer S, Robb P, Cowan K, Daly A, Shah K, Farmer A
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Lancet Diabetes and Endocrinology
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BMJ Global Health
Papoutsi C, Hargreaves D, Colligan G, Hagell A, Patel A, Campbell-Richards D, Viner R, Vijayaraghavan S et al.
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Group clinics for young adults with diabetes in an ethnically diverse, socioeconomically deprived setting (TOGETHER study): protocol for a realist review, co-design and mixed methods, participatory evaluation of a new care model
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BMJ Open
Finer S, Lowe R, Ogunkolade W, Bhowmik B, Hussain A, Khan AKA, Rakyan V, Hitman GA
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The influence of maternal and offspring environment on genome-wide methylation of the offspring in Bangladesh
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Is famine exposure during developmental life in rural Bangladesh associated with a metabolic and epigenetic signature in young adulthood? A historical cohort study
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BMJ Open
Kage A, Cowan F, Kempley S, Finer S, Hogg M, Hitman G, Shah D
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HEAD CIRCUMFERENCE IS DIRECTLY RELATED TO SPECIFIC LINEAR MEASUREMENTS OF CEREBRAL STRUCTURES IN A LOCAL EAST LONDON POPULATION OF WELL NEWBORNS OF SOUTH ASIAN DIASPORA
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ANNALS OF NUTRITION AND METABOLISM
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Greenhalgh T, Clinch M, Afsar N, Choudhury Y, Sudra R, Campbell-Richards D, Claydon A, Hitman GA et al.
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BMC Medicine
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Adaikalakoteswari A, Finer S, Voyias PD, McCarthy CM, Vatish M, Moore J, Smart-Halajko M, Bawazeer N et al.
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Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes
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Clinical Epigenetics
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Gestational Diabetes Mellitus and the Offspring—Jack and Jill Are Different Still
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Fetal programming via maternal diabetes: the controversy continues
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Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates
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Epigenetics
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Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring
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Vitamin B12 deficiency induces cholesterol biosynthesis by limiting S-adenosyl methionine and altering the methylation of SREBF1 and LDLR genes
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DIABETIC MEDICINE
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The role of the one-carbon cycle in the developmental origins of Type 2 diabetes and obesity
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DNA methylation variants in young adult offspring exposed to famine during postnatal life in Bangladesh
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Diabet Med
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Hillman SL, Finer S, Smart MC, Rakyan V, Hitman GA, Williams DJ
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Identification of Novel DNA Methylation Profiles Associated with Gene Regulation and Metabolic Pathways in Growth Restricted Offspring
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Maternal Gestational Diabetes Is Associated with Genome-Wide Methylation Variation in Placenta and Cord Blood of Exposed Offspring
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DIABETES
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Variation in phenotype and DNA methylation is detectable in an observational cohort of young adult Bangladeshis exposed to famine during in utero and postnatal life
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Act now against new NHS competition regulations: an open letter to the BMA and the Academy of Medical Royal Colleges calls on them to make a joint public statement of opposition to the amended section 75 regulations
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Inadequate Vitamin D Status in Pregnancy
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Environmental and Molecular Mutagenesis
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Environ Mol Mutagen
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Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus
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Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
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A model of intrauterine hyperglycaemia provides evidence for fetal programming of glucose tolerance and a platform for epigenomic studies in mouse and human
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Longitudinal and Life Course Studies: international journal
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The 5th Conference on Epidemiology and Longitudonal Studies in Europe
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Global health-worker crisis: the UK could learn from Cuba
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Improving calibration without training: The role of task information
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Applied Cognitive Psychology
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Strengthening governance for global health research. Improved undergraduate and postgraduate training may raise awareness
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Constantinides M, Gafton J, Garcia ACA, Genes and Health, Dixon PH, Williamson C, Linton K, Finer S et al.
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A Genes & Health pilot recall study of intrahepatic cholestasis of pregnancy and cholestatic liver disease
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Finer S, Sze WC, Chandran D, Gupta V, Myint O, Joseph T, Hutchinson J, Saravanamuthu J et al.
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A high prevalence of Type 2 diabetes, ethnic diversity and social deprivation in women presenting to an East London antenatal clinic
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Conference:
Diabetes UK APC
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Glasgow
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from:
03/2008
Nongmaithem SS, Beaumont RN, Dedaniya A, Wood AR, Ogunkolade B-W, Hassan Z, Krishnaveni GV, Kumaran K et al.
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Associations of genetic scores for birth weight with newborn size and later Anthropometric traits and cardiometabolic risk markers in South Asians
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Nongmaithem S, Beaumont R, Dedaniya A, Wood A, Ogunkolade B, Hassan Z, Krishnaveni G, Kumaran K et al.
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Associations of genetic scores for birth weight with newborn size and later anthropometric traits and cardiometabolic risk markers in South Asians
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Finer S, Webster G, Bhattacharya S, Vijayaraghavan S
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Autoimmune pancreatitis: an emerging disease entity causing steroid-responsive diabetes
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Conference:
Society for Endocrinology Clinical Cases Meeting
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London
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from:
02/2009
Orazumbekova B, Zöllner J, Hodgson S, Bigossi M, Samuel M, Team GAHR, Finer S, Mathur R et al.
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BMI inadequately mediates the relationship between polygenic risk of adiposity and early onset type 2 diabetes in south Asians
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Garrod-Ketchely C, Callender LA, Schroth J, Littlewood K, Carroll EC, Tamsan D, Tsang VS, Nessel I et al.
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Characterisation of the dual roles of senescent-like T cells that arise during healthy and unhealthy ageing
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Mathur R, Hull SA, Hodgson S, Finer S
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Characterisation of type 2 diabetes subgroups and their association with ethnicity and clinical outcomes: a UK real-world data study using the East London Database
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Finer S, Martin HC, Khan A, Hunt KA, MacLaughlin B, Ahmed Z, Ashcroft R, Durham C et al.
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Cohort Profile: East London Genes & Health (ELGH), a community based population genomics and health study of British-Bangladeshi and British-Pakistani people
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Stow D, Tsang RSM, Katzourou I, Underwood JFG, Collaborative TLMR, Holmans P, Barroso I, Martin H et al.
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Combining polygenic risk scores to understand genetic liability to physical-mental health multimorbidity in UK BioBank
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McGregor TL, Hunt KA, Nioi P, Mason D, Ticau S, Pelosi M, Loken PR, Finer S et al.
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Deep phenotyping of a healthy human HAO1 knockout informs therapeutic development for primary hyperoxaluria type 1
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Mansell A, Gouveia C, Braggins F, Claydon A, Nobeebux A, Joseph T, Balakumar Y, Savaranamuthu J et al.
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Early screening for gestational diabetes mellitus is essential to detect undiagnosed impaired glucose tolerance and Type 2 diabetes in a high risk, ethnically-diverse population
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Conference:
Diabetes UK Annual Professional Conference 2009
(
Glasgow
)
from:
11/03/2009
to:
13/03/2009
,
Eto F, Samuel M, Henkin R, Mahesh M, Ahmad T, Angdembe A, McAllister-Williams RH, Missier P et al.
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Ethnic differences in early onset multimorbidity and associations with health service use, long-term prescribing, years of life lost, and mortality: an observational study using person-level clustering in the UK Clinical Practice Research Datalink
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Orazumbekoba B, Hamdani T, Hodgson S, Samuel M, Stow D, Spreckley M, Finer S, Siddiqui MK et al.
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Evidence of ethnic variations in the relationships between routinely recorded clinical factors and T2D: a systematic review and meta-analysis
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Kim HI, DeBoever C, Walter K, Kalantzis G, Li C, Mozaffari SV, Kundu K, Jacobs BM et al.
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Exome sequencing and analysis of 44,028 British South Asians enriched for high autozygosity
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Hodgson S, Bui V, Bigossi M, Stow D, Maroteau C, Williamson A, Hu S, Blee AM et al.
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Exome-wide association study in 54,698 south Asians identifies novel type 2 diabetes associations with HNF4A and GP2
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Jacobs B, Stow D, Hodgson S, Zöllner J, Samuel M, Kanoni S, Bidi S, Team GAHR et al.
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Genetic architecture of routinely acquired blood tests in a UK cohort of South Asian ancestry reveals ancestry-specific causal variants
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Maxwell J, Mitchell BL, Du-Harpur X, Pardo LM, Witkam WCAM, Dand N, Bartels M, Betti MJ et al.
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Genome-wide association meta-regression identifies stem cell lineage orchestration as a key driver of acne risk
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Zhou W, Kanai M, Wu K-HH, Humaira R, Tsuo K, Hirbo JB, Wang Y, Bhattacharya A et al.
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Global Biobank Meta-analysis Initiative: powering genetic discovery across human diseases
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White SL, Brasher MS, Pattee J, Zhou W, Chapman S, Jee YH, Bell CC, Jamil TL et al.
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Global multi-ancestry genetic study elucidates genes and biological pathways associated with thyroid cancer and benign thyroid diseases
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PATEL AK, Finer S
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Group clinics for young adults with diabetes in an ethnically diverse, socioeconomically deprived setting (TOGETHER study): protocol for a realist review, co-design and mixed methods, participatory evaluation of a new care model
.
BMJ Open
Hodgson S, Huang QQ, Sallah N, Team GHR, Griffiths CJ, Newman WG, Trembath RC, Lumbers T et al.
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Harnessing the power of polygenic risk scores to predict type 2 diabetes and its subtypes in a high-risk population of British Pakistanis and Bangladeshis in a routine healthcare setting
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Taylor KM, Huerta-Chagoya A, Wang X, Vora M, Li J, Turk L, Heng TH, Kim J et al.
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Improving type 2 diabetes polygenic risk scores by incorporating rare, low-frequency, and population-specific variants
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Mclachlan S, KYRIMI E, Daley B, dude K, Marsden M, Finer S, Hitman G, Fenton N
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Incorporating Clinical Decisions into Standardised Caremaps
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Conference:
IEEE International Conference on Health Informatics (ICHI 2020)
Malawsky DS, van Walree E, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM et al.
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Influence of autozygosity on common disease risk across the phenotypic spectrum
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Team GD, Boutin T, Bretherick AD, Dibble JJ, Ewaoluwagbemiga E, Northwood E, Samms GL, Vitart V et al.
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Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome
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Liu T, Sankareswaran A, Paterson G, Team GHR, Fraser DP, Hodgson S, Huang QQ, Heng TH et al.
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Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores
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Henry A, Mo X, Finan C, Chaffin MD, Speed D, Issa H, Denaxas S, Ware JS et al.
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Mapping the aetiological foundations of the heart failure spectrum using human genetics
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Littlewood K, Gegic J, Hickman M, Henson R, Bishop J, Kershaw T, Diamond P, Slabaugh G et al.
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Metabolic dysfunction over a life course key to healthy ageing inequality
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Aging Clinical and Experimental Research
Meng X, Navoly G, Giannakopoulou O, Levey D, Koller D, Pathak G, Koen N, Lin K et al.
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Multi-ancestry GWAS of major depression aids locus discovery, fine-mapping, gene prioritisation, and causal inference
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Fejzo M, Wang X, Zöllner J, Pujol-Gualdo N, Laisk T, Team EBR, Finer S, van Heel DA et al.
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Multi-ancestry GWAS of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity
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Huerta-Chagoya A, Kim J, Mandla R, Lu Y, Suzuki K, Petty LE, Ng HK, Choi J et al.
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Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries
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Nunes CB, Rukins V, Cisse AH, White F, McBride N, Kuang A, Allard C, Ronkainen J et al.
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Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects
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Pietzner M, Williamson A, Hunt KA, Koprulu M, Kohleick L, Demircan K, Team GHR, Finer S et al.
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Nanoparticle enriched mass spectrometry proteomics in British South Asians identifies novel variant-protein-disease mechanisms
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Siddiqui M, Hodgson S, Williamson A, Stow D, Jacobs B, Samuel M, Gafton J, Zöllner J et al.
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Partitioned polygenic scores highlight role of beta-cell function and unfavourable fat distribution patterns in young onset type 2 diabetes in south Asians
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Law JH, Stow D, Hodgson S, Team GHR, van Heel DA, Newman WG, Osman M, Finer S
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Perceived risk of type 2 diabetes: Using linked genomic, clinical and questionnaire data to understand the potential use of genetic risk tools in British South Asians
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Zanini JC, Pietzner M, Koprulu M, Zoodsma M, Williamson A, Hunt KA, Manolias A, Walter K et al.
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Proteomic and clinical impact of human knockouts in British South Asians
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Zöllner J, Finer S, Linton KJ, Team GAHR, van Heel DA, Williamson C, Dixon PH
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Rare variant contribution to cholestatic liver disease in a South Asian population in the United Kingdom
.
Finer S, Bell C, Lindgren C, Wilson G, Rakyan V, Prokopenko I, Teschendorff A, Down T et al.
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The FTO obesity and Type 2 diabetes susceptibility haplotype is associated with SNP-dependent DNA methylation
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Conference:
Diabetes UK Annual Professional Conference 2010
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03/03/2010
to:
05/03/2010
,
Jacobs BM, Chandra A, Mandal A, Foote I, Durrani F, Waters S, Liu Y, Proitsi P et al.
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The contribution of Apoliproprotein E genetic variation to dementia risk in British South Asians
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Garrod-Ketchley C, Henson S, Mourgue d’Algue L, Littlewood K, HOOD G, Worthington A, Pattrick M, Sutcliffe C et al.
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The generation of senescent-like CD4+ EMRA T cells in T2D and their contribution to poor COVID-19 vaccine responses
.
Discovery Immunology
Stow D, Tsang R, Katzourou I, Huang Q, Samuel M, Team TGH, Collaborative TLMR, Payne R et al.
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The impact of genetic and sociodemographic factors on life course trajectories of physical-mental health multimorbidity in a UK South Asian cohort
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Pervjakova N, Moen G-H, Borges M-C, Ferreira T, Cook JP, Allard C, Beaumont RN, Canouil M et al.
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Trans-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
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Huang QQ, Sallah N, Dunca D, Trivedi B, Hunt KA, Hodgson S, Lambert SA, Arciero E et al.
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Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistanis and Bangladeshis
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Samuel M, Park RY, Eastwood SV, Eto F, Morton CE, Stow D, Bacon S, Mehrkar A et al.
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Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: an observational cohort study using the OpenSAFELY platform
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Zöllner J, Orazumbekova B, Hodgson S, Team GAHR, van Heel DA, Iliodromiti S, Siddiqui M, Mathur R et al.
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Understanding the potential contribution of polygenic risk scores to the prediction of gestational and type 2 diabetes in women from British Pakistani and Bangladeshi groups: a cohort study in Genes and Health
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Samuel M, Park RY, Eastwood SV, Eto F, Morton CE, Stow D, Bacon S, Goldacre B et al.
.
Weight trends amongst adults with diabetes or hypertension during the COVID-19 pandemic: an observational study using OpenSAFELY
.
Dupuis T, Anjana RM, Srinivasan S, Dawed AY, Melhem A, Bigossi M, Taylor A, Adedire ET et al.
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XBP1 expression in pancreatic islet cells is associated with poor glycaemic control across ancestries especially in young non-obese onset diabetes
.