Publications: P John Marshall

Laforêts F, Kotantaki P, Elorbany S, Hartlebury J, Joy JD, Malacrida B, Bryan-Ravenscroft RC, Berlato C et al. ( 2025 ) . Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian cancer .

( 2025 ) . The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model . Cancers vol. 17 , ( 9 ) 1534 - 1534 .

Bolton CL, O'Sullivan R, Menezes S, Cameron AJ, Marin G, Marshall JF, Carter EP, Henkemeyer M et al. ( 2025 ) . Abstract 3859: Ephrin inhibition disrupts stromal-cancer crosstalk and reduces metastasis in pancreatic cancer . Cancer Research vol. 85 , ( 8_Supplement_1 ) 3859 - 3859 .

( 2025 ) . Use of metabolic imaging to monitor heterogeneity of tumour response following therapeutic mTORC1/2 pathway inhibition . Disease Models & Mechanisms vol. 18 , ( 2 ) Article DMM050804 ,

( 2025 ) . Visualizing Cancer Heterogeneity at the Molecular and Cellular Levels: Lessons from Rosetta . Cancer Discovery vol. 15 , ( 1 ) 34 - 38 .

( 2024 ) . A trafficking regulatory subnetwork governs α\n _V\n β\n ₆\n integrin-HER2 cross-talk to control breast cancer invasion and drug resistance . Science Advances vol. 10 , ( 49 ) Article eadk9944 ,

( 2024 ) . Syngeneic Mouse Models for Pre-Clinical Evaluation of CAR T Cells . Cancers vol. 16 , ( 18 ) 3186 - 3186 .

( 2024 ) . Integrin-αvβ6 targeted peptide-toxin therapy in a novel αvβ6-expressing immunocompetent model of pancreatic cancer . Pancreatology vol. 24 , ( 3 ) 445 - 455 .

( 2024 ) . Understanding Predictors of Crohn’s Disease: Determinants of Altered Barrier Function in Pre-Disease Phase of Crohn’s Disease . Journal of the Canadian Association of Gastroenterology vol. 7 , ( 1 ) 68 - 77 .

( 2024 ) . Selective placement of functionalised DNA origami <i>via</i> thermal scanning probe lithography patterning . Materials Advances vol. 5 , ( 23 ) 9376 - 9382 .

( 2023 ) . 53P Integrin-αvβ6 targeted CAR T cells in an immunocompetent orthotopic model of pancreatic cancer . Immuno-Oncology and Technology vol. 20 , Article 100526 , 100526 - 100526 .

( 2023 ) . A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance .

( 2023 ) . A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance .

( 2023 ) . Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis . Gastroenterology vol. 164 , ( 4 ) 619 - 629 .

( 2023 ) . β₃A-Integrin Downregulates the Urokinase-Type Plasminogen Activator Receptor (u-PAR) through a<i>PEA3/ets</i> Transcriptional Silencing Element in the u-PAR Promoter . Molecular and Cellular Biology vol. 21 , ( 6 ) 2118 - 2132 .

( 2023 ) . αv Integrin-Dependent TGFβ Activation in Cancer: A Brief Update . Biology of Extracellular Matrix , Springer International Publishing

( 2023 ) . TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression . npj Breast Cancer vol. 9 , ( 1 ) Article 9 ,

( 2022 ) . Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion . npj Breast Cancer vol. 8 , ( 1 ) Article 109 ,

( 2022 ) . Ligand-bound integrin αvβ6 internalisation and trafficking . Frontiers in Cell and Developmental Biology vol. 10 , Article 920303 ,

( 2022 ) . Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma . Molecules vol. 27 , ( 14 ) 4331 - 4331 .

Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A et al. ( 2022 ) . Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion . Cell Reports vol. 38 , ( 4 ) Article 110227 , 110227 - 110227 .

Kashani R, Khan N, Foster J, Young J, Marshall J, Sosabowski JK ( 2022 ) . Optimisation of αvβ6-specific peptides for use in targeted radionuclide therapy . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 49 , S142 - S142 .

( 2021 ) . Abstract 958: Effective targeting of pancreatic ductal adenocarcinoma metastases with an integrin αvβ6-targeting peptide-drug conjugate . Cancer Research vol. 81 , ( 13_Supplement ) 958 - 958 .

( 2021 ) . Current Perspectives on the Use of off the Shelf CAR-T/NK Cells for the Treatment of Cancer . Cancers vol. 13 , ( 8 ) 1926 - 1926 .

( 2021 ) . CEACAM7 Is an Effective Target for CAR T-cell Therapy of Pancreatic Ductal Adenocarcinoma . Clinical Cancer Research vol. 27 , ( 5 ) 1538 - 1552 .

( 2021 ) . Harnessing the power of foot-and-mouth-disease virus for targeting integrin alpha-v beta-6 for the therapy of cancer . Expert Opinion on Drug Discovery vol. 16 , ( 7 ) 737 - 744 .

( 2021 ) . The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer . Nature Genetics vol. 53 , ( 1 ) 16 - 26 .

( 2021 ) . Effective targeting of pancreatic ductal adenocarcinoma metastases with an integrin avβ6-targeting peptide-drug conjugate . CANCER RESEARCH . vol. 81 ,

( 2021 ) . Relationship between altered myoepithelial phenotype and the inflammatory cell infiltrate in progression of DCIS . BREAST . vol. 56 , S34 - S34 .

( 2020 ) . Human and Murine CAR T cells for targeting integrin Alpha V Beta 6 in Pancreatic Ductal Adenocarcinoma . Pancreatology vol. 20 , ( 8 ) e21 - e21 .

( 2020 ) . Loss of the laminin subunit alpha‐3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma* . British Journal of Dermatology vol. 184 , ( 5 ) 923 - 934 .

( 2020 ) . Switchable CAR-T cells mediate long-term remission of PDAC . Pancreatology vol. 20 , ( 8 ) e8 - e8 .

( 2020 ) . The ITGB6 gene: its role in experimental and clinical biology . Gene vol. 763 , Article 100023 , 100023 - 100023 .

( 2020 ) . VAR2CSA-based CAR-T cells for the treatment of pancreatic ductal adenocarcinoma . Pancreatology vol. 20 , ( 8 ) e6 - e7 .

( 2020 ) . αvβ6 targeted CAR-T cells in immunocompetent orthotopic murine PDAC . Pancreatology vol. 20 , ( 8 ) e6 - e6 .

( 2020 ) . Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn’s disease subjects . BMC Medical Genetics vol. 21 , ( 1 ) Article 204 ,

( 2020 ) . Epidermolysis bullosa . Nature Reviews Disease Primers vol. 6 , ( 1 ) Article 78 ,

Dexter K, BROWN N, Foster J, Kashani R, CHUPIN J, Cleaver J, Cutmore L, Marshall J et al. ( 2020 ) . Simultaneous dual isotope PET-SPECT/CT imaging of pancreatic cancer . Presented at: EMIM 2020 ,

Cutmore LC, Brown NF, Raj D, Chauduri S, Wang P, Maher J, Wang Y, Lemoine NR et al. ( 2020 ) . Pancreatic Cancer UK Grand Challenge: Developments and challenges for effective CAR T cell therapy for pancreatic ductal adenocarcinoma . Pancreatology vol. 20 , ( 3 ) 394 - 408 .

( 2020 ) . Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus . Theranostics vol. 10 , ( 7 ) 2930 - 2942 .

( 2019 ) . The ITGB6 gene: its role in experimental and clinical biology . Gene vol. 763S ,

( 2019 ) . Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment . Cancers vol. 11 , ( 9 ) 1221 - 1221 .

( 2019 ) . The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy . The Journal of Pathology vol. 249 , ( 3 ) 332 - 342 .

( 2019 ) . Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 100 , A39 - A39 .

( 2019 ) . Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control . Faraday Discussions vol. 219 , 203 - 219 .

( 2018 ) . DNA Origami Nanoarrays for Multivalent Investigations of Cancer Cell Spreading with Nanoscale Spatial Resolution and Single-Molecule Control . ACS Nano vol. 13 , ( 1 ) 728 - 736 .

( 2018 ) . A framework for the development of effective anti-metastatic agents . Nature Reviews Clinical Oncology vol. 16 , ( 3 ) 185 - 204 .

Rudran B, Reader C, Foster J, Hodivala-Dilke K, Sosabowski J, Marshall J ( 2018 ) . P1.03-19 Antibody Blockade of Integrin Alpha-V-Beta-6 (avb6) as a Novel Treatment for NSCLC . Journal of Thoracic Oncology . vol. 13 , S518 - S519 .

( 2018 ) . Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion .

( 2018 ) . Correlative 3D Structured Illumination Microscopy and Single-Molecule Localization Microscopy for Imaging Cancer Invasion . 253 - 265 .

( 2018 ) . PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer . Cell Reports vol. 22 , ( 9 ) 2469 - 2481 .

Man YKS, Davies JA, Coughlan L, Pantelidou C, Blázquez-Moreno A, Marshall JF, Parker AL, Halldén G ( 2018 ) . The Novel Oncolytic Adenoviral Mutant Ad5-3Δ-A20T Retargeted to αvβ6 Integrins Efficiently Eliminates Pancreatic Cancer Cells . Molecular Cancer Therapeutics vol. 17 , ( 2 ) 575 - 587 .

( 2018 ) . Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor? . Clinical Cancer Research vol. 24 , ( 2 ) 253 - 255 .

Rudran B, Reader C, Foster J, Hodivala-Dilke K, Sosabowski J, Marshall J ( 2018 ) . Blockade of integrin alpha-v-beta-6 (αvβ6) reduces the invasive potential of NSCLC . LUNG CANCER . vol. 115 , S5 - S6 .

( 2018 ) . Loss of Lamα3 drives M2 macrophage differentiation in squamous cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E399 - E400 .

( 2017 ) . 336 Tumour associated macrophage recruitment in SCC . Journal of Investigative Dermatology . vol. 137 , S250 - S250 .

Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic RMG, Kao YV, Saxena SA, Romain A et al. ( 2017 ) . Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells . Molecular Therapy vol. 25 , ( 10 ) 2427 - 2427 .

( 2017 ) . Integrins as Therapeutic Targets: Successes and Cancers . Cancers vol. 9 , ( 9 ) 110 - 110 .

( 2017 ) . Pro‐migratory and TGF‐β‐activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8‐dependent GTPase switch . The Journal of Pathology vol. 243 , ( 1 ) 37 - 50 .

( 2017 ) . Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality . European Journal of Medicinal Chemistry vol. 136 , 154 - 164 .

Hodgins NO, Al-Jamal WT, Wang JT-W, Klippstein R, Costa PM, Sosabowski JK, Marshall JF, Maher J et al. ( 2017 ) . Investigating in vitro and in vivo αvβ6 integrin receptor-targeting liposomal alendronate for combinatory γδ T cell immunotherapy . Journal of Controlled Release vol. 256 , 141 - 152 .

( 2017 ) . Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function . Breast Cancer Research vol. 19 , ( 1 ) Article 33 ,

Rudran B, Desai A, Luzarraga M, Hodivala-Dilke K, Foster J, Sosabowski J, Marshall J ( 2017 ) . 6: Development of non-invasive imaging of integrin alpha-v-beta-6 (αvβ6)-positive lung cancers in advance of testing αvβ6-targeted therapies . Lung Cancer vol. 103 , S4 - S4 .

Rudran B, Desai A, Luzarraga M, Hodivala-Dilke K, Foster J, Sosabowski J, Marshall J ( 2017 ) . Development of non-invasive imaging of integrin alpha-v-beta-6 (αvβ6)-positive lung cancers in advance of testing αvβ6-targeted therapies . LUNG CANCER . vol. 103 , S4 - S4 .

( 2017 ) . Myoepithelial Cell Phenotype in DCIS Progression: Functional Significance of Integrin αvβ6 and Fibronectin . JOURNAL OF PATHOLOGY . vol. 243 , S16 - S16 .

Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic RMG, Kao YV, Saxena SA, Romain A et al. ( 2017 ) . Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells . Molecular Therapy vol. 25 , ( 1 ) 259 - 273 .

Man YKS, Davies JA, Coughlan L, Pantelidou C, Marshall JF, Parker AL, Hallden G ( 2017 ) . The novel oncolytic adenoviral mutant Ad5-3Δ-A20T retargeted to αvβ6-integrins efficiently eliminates pancreatic cancer cells . HUMAN GENE THERAPY . vol. 28 , A27 - A27 .

( 2016 ) . Abstract A18: The integrin αvβ6 regulates PDAC cell growth and stromal cell behavior . Cancer Research vol. 76 , ( 24_Supplement ) A18 - A18 .

Vallath S, Reader C, Morton J, Sansom O, Evans J, Biankin A, Barry ST, Kocher H et al. ( 2016 ) . Abstract B53: The integrin αvβ6 is a promising therapeutic target for treating PDAC . Cancer Research . vol. 76 , B53 - B53 .

( 2016 ) . P112 &lt;break /&gt; Discovery of a Novel, High Affinity, Small Molecule αvβ6 Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis . QJM: An International Journal of Medicine

( 2016 ) . 472 Loss of Laminin α3 drives SCC invasion via ROCK signalling . Journal of Investigative Dermatology . vol. 136 , S241 - S241 .

( 2016 ) . The role of integrins in TGFβ activation in the tumour stroma . Cell and Tissue Research vol. 365 , ( 3 ) 657 - 673 .

( 2016 ) . Modifying oncolytic viral therapy for pancreatic cancer . Pancreatology vol. 16 , ( 3 ) S4 - S4 .

( 2016 ) . The integrin αvβ6 is a promising therapeutic target for treating PDAC . Pancreatology vol. 16 , ( 3 ) S6 - S6 .

( 2016 ) . The role of Galectin-7 in normal and DCIS-associated myoepithelial cells: predicting progression of DCIS . European Journal of Surgical Oncology (EJSO) vol. 42 , ( 5 ) S56 - S56 .

( 2016 ) . The fibronectin/α3β1 integrin axis serves as molecular basis for keratinocyte invasion induced by βHPV . Oncogene vol. 35 , ( 34 ) 4529 - 4539 .

( 2016 ) . Pharmacological Characterization of the αvβ6 Integrin Binding and Internalization Kinetics of the Foot-and-Mouth Disease Virus Derived Peptide A20FMDV2 . Pharmacology vol. 97 , ( 3-4 ) 114 - 125 .

Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic R, Violette S, Ghaem-Maghami S, Vallath S et al. ( 2016 ) . Abstract B129: Chimeric antigen receptor T-cells targeting the αvβ6 integrin demonstrate potent antitumor activity in multiple solid tumors . Cancer Immunology Research . vol. 4 , B129 - B129 .

( 2016 ) . Investigating the Functional Significance of Aberrant αvβ6 and Fibronectin Expression in Myoepithelial Cells: Role in the Progression of DCIS? . JOURNAL OF PATHOLOGY . vol. 240 , 28 - 28 .

Pantelidou C, Man YKS, Coughlan L, Marshall J, Kocher H, Hallden G ( 2016 ) . Oncolytic adenoviral mutants deleted in the anti-apoptotic E1B19K gene sensitize pancreatic cancer cells to drug-induced DNA damage . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 38 , S58 - S58 .

( 2016 ) . ROCK and Rac1 signalling in squamous cell carcinoma with loss of laminin 332 . BRITISH JOURNAL OF DERMATOLOGY . vol. 174 , E51 - E51 .

( 2016 ) . Single-molecule investigations via DNA nanostructures: A cell adhesion study . ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY . vol. 252 ,

( 2015 ) . Suppression of TGF_βand Angiogenesis by Type VII Collagen in Cutaneous SCC . Journal of the National Cancer Institute vol. 108 , ( 1 ) djv293 - djv293 .

Reader CS, Vallath S, Morton J, Steele C, Kocher HM, Keyse SM, Sansom O, Marshall JF ( 2015 ) . Abstract B87: Cell lines generated from PDAC transgenic mice reveal integrin αvβ6 modifies the invasive phenotype of pancreatic cancer . Cancer Research . vol. 75 , B87 - B87 .

( 2015 ) . Hedgehog Inhibition Results in the Upregulation of Pro-Tumourigenic αvβ6 Integrin Expression and Function in Cancer . Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology vol. 119 , ( 3 ) e106 - e106 .

( 2015 ) . 7: The integrin αvβ6: a new target for therapy in non-small cell lung cancer . Lung Cancer . vol. 87 , S3 - S3 .

( 2015 ) . Skin type VII collagen acts as a tumour suppressor by regulating TGFβ and angiogenesis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 135 , S28 - S28 .

( 2015 ) . Squamous Cell Carcinoma progression and Laminin 332 . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 135 , S23 - S23 .

Paillas S, Desai A, Quetier I, Marshall J, Pouget J, Sosabowski J ( 2015 ) . Targeted Radionuclide Therapy using high-LET particle emitter-labeled vectors against alpha-v-beta6-expressing cancers . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 42 , S201 - S201 .

Haider S, Wang J, Nagano A, Desai A, Arumugam P, Dumartin L, Fitzgibbon J, Hagemann T et al. ( 2014 ) . A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma . Genome Medicine vol. 6 , ( 12 ) Article 105 ,

( 2014 ) . αvβ6 Expression in Myoepithelial Cells: A Novel Marker for Predicting DCIS Progression with Therapeutic Potential . Cancer Research vol. 74 , ( 21 ) 5942 - 5947 .

( 2014 ) . Abstract B046: Therapeutic targeting of integrin αvβ6 in high-risk breast cancer . Molecular Cancer Research vol. 11 , ( 10_Supplement ) B046 - B046 .

( 2014 ) . Therapeutic Targeting of Integrin αvβ6 in Breast Cancer . JNCI: Journal of the National Cancer Institute vol. 106 , ( 8 )

( 2014 ) . Rigidity sensing and adaptation through regulation of integrin types . Nature Materials vol. 13 , ( 6 ) 631 - 637 .

( 2014 ) . Suppression of Hedgehog signalling promotes pro‐tumourigenic integrin expression and function . The Journal of Pathology vol. 233 , ( 2 ) 196 - 208 .

Vallath S, Gadaletta E, Chelala C, Scarpa A, Hart IR, Kocher HM, Marshall JF ( 2012 ) . Abstract B42: Toward targeting integrin αvβ6 for the therapy of pancreatic cancer . Therapy . Conference: Abstracts: AACR Special Conference on Pancreatic Cancer: Progress and Challenges; June 18-21, 2012; Lake Tahoe, NVB42 - B42 .

( 2014 ) . The integrin αvβ6 is a promising target for the therapy of PDAC: toward phase I trials . Pancreatology vol. 14 , ( 2 ) e3 - e3 .

Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA et al. ( 2014 ) . Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence . Clinical Cancer Research vol. 20 , ( 2 ) 344 - 357 .

( 2014 ) . Development of a novel approach for targeted delivery of siRNA to B lymphocytes with a potential application in cancer . HUMAN GENE THERAPY . vol. 25 , A5 - A5 .

( 2014 ) . Diverse roles for laminin 332 subunits in squamous cell carcinoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 134 , S19 - S19 .

( 2014 ) . Diverse roles for laminin-332 subunits in squamous cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 170 , E26 - E26 .

( 2013 ) . Abstract P4-15-01: Integrin avb6 is a therapeutic target for high-risk breast cancer and enhances trastuzumab efficacy . Cancer Research vol. 73 , ( 24_Supplement )

Ene–Obong A, Clear AJ, Watt J, Wang J, Fatah R, Riches JC, Marshall JF, Chin–Aleong J et al. ( 2013 ) . Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma . Gastroenterology vol. 145 , ( 5 ) 1121 - 1132 .

( 2013 ) . Preclinical SPECT/CT Imaging of αvβ6 Integrins for Molecular Stratification of Idiopathic Pulmonary Fibrosis . Journal of Nuclear Medicine vol. 54 , ( 12 ) 2146 - 2152 .

( 2013 ) . Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer . Breast Cancer Research vol. 15 , ( 5 ) Article R92 ,

( 2013 ) . Generation and Characterization of a Diabody Targeting the αvβ6 Integrin . PLoS ONE vol. 8 , ( 9 ) e73260 - e73260 .

( 2013 ) . Structural Guided Scaffold Phage Display Libraries as a Source of Bio-Therapeutics . PLoS ONE vol. 8 , ( 8 ) e70452 - e70452 .

( 2013 ) . Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma . Nature Genetics vol. 45 , ( 8 ) 923 - 926 .

( 2013 ) . Single-cell paired-end genome sequencing reveals structural variation per cell cycle . Nucleic Acids Research vol. 41 , ( 12 ) 6119 - 6138 .

( 2013 ) . Diverse roles for laminin 332 subunits in squamous cell carcinoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S64 - S64 .

( 2013 ) . Formation and inhibition of invadopodia in oral squamous cell carcinoma . MOLECULAR BIOLOGY OF THE CELL . vol. 24 ,

( 2013 ) . Loss of type VII collagen in cutaneous SCC increases angiogenesis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S158 - S158 .

( 2013 ) . MMP-8 Loss Contributes to Altered Myoepithelial Cell Function in DCIS . JOURNAL OF PATHOLOGY . vol. 229 , S11 - S11 .

( 2013 ) . Pre-Clinical Imaging Of The αvβ6 Integrin For Molecular Stratification Of Idiopathic Pulmonary Fibrosis . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 187 ,

( 2013 ) . Rigidity sensing and adaptation through regulation of integrin populations . MOLECULAR BIOLOGY OF THE CELL vol. 24 ,

( 2012 ) . S66 Targeted in Vivo Imaging of the αvβ6 Integrin in Mice with Bleomycin-Induced Lung Fibrosis . Thorax . vol. 67 , A33.2 - A33 .

( 2012 ) . A human monoclonal antibody 264RAD targeting αvβ6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo . Oncogene vol. 32 , ( 37 ) 4406 - 4416 .

( 2012 ) . 16P Myoepithelial Control of the Inflammatory Microenvironment Promotes Transition of Dcis to Invasive Disease . Annals of Oncology vol. 23 , ii19 - ii19 .

( 2012 ) . S100P-Binding Protein, S100PBP, Mediates Adhesion through Regulation of Cathepsin Z in Pancreatic Cancer Cells . The American Journal of Pathology vol. 180 , ( 4 ) 1485 - 1494 .

( 2012 ) . Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer . Cell vol. 148 , ( 4 ) 780 - 791 .

( 2012 ) . Loss of MMP-8 Expression Contributes to Altered Myoepithelial Cell Function in DCIS . JOURNAL OF PATHOLOGY . vol. 226 , S13 - S13 .

( 2012 ) . Loss of keratinocyte type VII collagen in SCC increases TGF-beta signalling and angiogenesis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 132 , S45 - S45 .

( 2012 ) . Loss of type VII collagen in squamous cell carcinoma increases angiogenesis <i>in vitro</i> and <i>in vivo</i> . BRITISH JOURNAL OF DERMATOLOGY . vol. 166 , e25 - e26 .

( 2012 ) . MYOEPITHELIAL CONTROL OF THE INFLAMMATORY MICROENVIRONMENT PROMOTES TRANSITION OF DCIS TO INVASIVE DISEASE . ANNALS OF ONCOLOGY . vol. 23 , 19 - 19 .

( 2012 ) . NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin αvβ6 ligand specificity . RSC Advances vol. 2 , ( 29 ) 11019 - 11019 .

( 2012 ) . NanoSPECT/CT imaging of pulmonary αvβ6 with [In-111]A20FMDV2 as a surrogate marker for monitoring lung fibrosis . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 39 , S215 - S215 .

( 2012 ) . Up-regulation of αvβ6 integrin and fibronectin EDA in myoepithelial cells contribute to the angiogenic switch in pre-invasive breast cancer . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 93 , A24 - A24 .

( 2011 ) . P2-01-05: Integrin avb6 Mediates HER2−Driven Invasion in Breast Cancer . Cancer Research vol. 71 , ( 24_Supplement )

( 2011 ) . Re: Exome Sequencing Identifies Frequent Mutation of the SWI/SNF Complex Gene PBRM1 in Renal Carcinoma . Journal of Urology vol. 186 , ( 3 ) 1150 - 1150 .

( 2011 ) . Transwell® Invasion Assays . 97 - 110 .

( 2011 ) . The role of α9β1 integrin in modulating epithelial cell behaviour . Journal of Oral Pathology &amp; Medicine vol. 40 , ( 10 ) 755 - 761 .

( 2011 ) . Psoriasin (S100A7) associates with integrin beta 6 subunit and is required for alpha v beta 6-dependent carcinoma cell invasion . ONCOGENE vol. 30 , ( 12 ) 1422 - 1435 .

Marsh D, Suchak K, Moutasim KA, Vallath S, Hopper C, Jerjes W, Upile T, Kalavrezos N et al. ( 2011 ) . Stromal features are predictive of disease mortality in oral cancer patients . J PATHOL vol. 223 , ( 4 ) 470 - 481 .

( 2011 ) . Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis . J PATHOL vol. 223 , ( 3 ) 366 - 377 .

Marsh D, Suchak K, Moutasim KA, Vallath S, Hopper C, Jerjes W, Upile T, Kalavrezos N et al. ( 2011 ) . Stromal features are predictive of disease mortality in oral cancer patients . The Journal of pathology vol. 223 , ( 4 ) 470 - 481 .

( 2011 ) . Loss of type VII collagen in SCC leads to increased invasion and TGF-beta signalling <i>in vivo</i> . BRITISH JOURNAL OF DERMATOLOGY . vol. 164 , 910 - 910 .

( 2011 ) . Loss of type VII collagen in squamous cell carcinoma leads to increased invasion and TGF-beta signalling <i>in vivo</i> . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 131 , S33 - S33 .

( 2010 ) . Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis . The Journal of pathology vol. 223 , ( 3 ) 366 - 377 .

( 2010 ) . EP4-mediated prostanoid signalling promotes oral cancer progression . BMC Proceedings vol. 4 , ( S2 ) Article P35 ,

Saha A, Ellison D, Thomas GJ, Vallath S, Mather SJ, Hart IR, Marshall JF ( 2010 ) . High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alpha v beta 6 . J PATHOL vol. 222 , ( 1 ) 52 - 63 .

( 2010 ) . Pancreatic cancer organotypic cultures . JOURNAL OF BIOTECHNOLOGY vol. 148 , ( 1 ) 16 - 23 .

( 2010 ) . Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis . J LEUKOCYTE BIOL vol. 87 , ( 5 ) 877 - 884 .

( 2010 ) . Alkaloid-dependent upregulation of AlphavBeta6 integrin promotes oral submucous fibrosis . ORAL DISEASES vol. 16 , ( 6 ) 528 - 528 .

( 2010 ) . Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines . BREAST CANCER RES vol. 12 , ( 4 ) Article R51 ,

Wagstaff JL, Vallath S, Marshall JF, Williamson RA, Howard MJ ( 2010 ) . Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein–peptide interactions . Chemical Communications vol. 46 , ( 40 ) 7533 - 7533 .

Jones J, Allen M, Thomas G, Dawoud M, Vallath S, Payne S, Edwards D, Pennington C et al. ( 2009 ) . DCIS-Associated Myoepithelial Cells Expressing the αvβ6 Integrin Modify Tumour Cell Behaviour: A Predictor of Invasive Progression? . Cancer Research vol. 69 , ( 24_Supplement ) 4159 - 4159 .

( 2009 ) . Myoepithelial Cells in DCIS Exhibit an Altered Phenotype and Promote Angiogenesis . Cancer Research vol. 69 , ( 24_Supplement ) 2155 - 2155 .

( 2009 ) . alpha v beta 3 Integrin Limits the Contribution of Neuropilin-1 to Vascular Endothelial Growth Factor-induced Angiogenesis . J BIOL CHEM vol. 284 , ( 49 ) 33966 - 33981 .

( 2009 ) . High-throughput in vivo screening of targeted molecular imaging agents . Proceedings of the National Academy of Sciences vol. 106 , ( 42 ) 17904 - 17909 .

( 2009 ) . Targeted <i>In vivo</i> Imaging of Integrin αvβ6 with an Improved Radiotracer and Its Relevance in a Pancreatic Tumor Model . Cancer Research vol. 69 , ( 14 ) 5843 - 5850 .

Coughlan L, Vallath S, Saha A, Flak M, McNeish IA, Vassaux G, Marshall JF, Hart IR et al. ( 2009 ) . In Vivo Retargeting of Adenovirus Type 5 to alpha v beta 6 Integrin Results in Reduced Hepatotoxicity and Improved Tumor Uptake following Systemic Delivery . J VIROL vol. 83 , ( 13 ) 6416 - 6428 .

( 2009 ) . Evaluation of [⁶⁴Cu]Cu-DOTA and [⁶⁴Cu]Cu-CB-TE2A Chelates for Targeted Positron Emission Tomography with an α_vβ₆-Specific Peptide . Molecular Imaging vol. 8 , ( 2 ) Article 7290.2009.00015 ,

( 2009 ) . A role for α5β1 integrin in leukocyte accumulation in acute peritonitis . EUROPEAN JOURNAL OF CLINICAL INVESTIGATION . vol. 39 , 22 - 23 .

( 2009 ) . An Ad5 Vector Retargeted to αvβ6 Displays Improved Tumour Transduction Combined with Reduced Liver Uptake Following Systemic Delivery . MOLECULAR THERAPY . vol. 17 , S323 - S323 .

( 2009 ) . Myoepithelial Cells in DCIS Exhibit an Altered Phenotype and Promote Angiogenesis . CANCER RESEARCH . vol. 69 , 642S - 643S .

( 2008 ) . Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus . J MOL BIOL vol. 382 , ( 2 ) 385 - 401 .

( 2008 ) . Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues . J MOL BIOL vol. 379 , ( 4 ) 645 - 655 .

( 2008 ) . De novo expression of αvβ6 integrin by myoepithelial cells in ductal carcinoma in situ may be an important marker of disease progression . Breast Cancer Research . vol. 10 ,

( 2008 ) . αvβ6 Integrin Promotes the Invasion of Morphoeic Basal Cell Carcinoma through Stromal Modulation . Cancer Research vol. 68 , ( 9 ) 3295 - 3303 .

( 2008 ) . Foot-and-mouth disease virus forms a highly stable, EDTA-resistant complex with its principal receptor, integrin alpha v beta 6: Implications for infectiousness . J VIROL vol. 82 , ( 3 ) 1537 - 1546 .

( 2008 ) . CMR 2007: 4.04: Improved molecular imaging probe for <i>in vivo</i> detection of the integrin α_vβ₆ . Contrast Media &amp; Molecular Imaging vol. 2 , ( 6 ) 284 - 284 .

( 2008 ) . EFFECT OF PHOTODYNAMIC THERAPY ON ANTITUMOR IMMUNE DEFENSES: COMPARISON OF THE PHOTOSENSITIZERS HEMATOPORPHYRIN DERIVATIVE AND CHLORO‐ALUMINUM SULFONATED PHTHALOCYANINE . Photochemistry and Photobiology vol. 49 , ( 5 ) 627 - 632 .

( 2008 ) . PHOTODYNAMIC THERAPY OF A MURINE TUMOR FOLLOWING SENSITISATION WITH CHLORO ALUMINUM SULFONATED PHTHALOCYANINE . Photochemistry and Photobiology vol. 46 , ( 5 ) 867 - 871 .

( 2008 ) . PHOTOSENSITISING ACTIVITY OF PHTHALOCYANINE DYES SCREENED AGAINST TISSUE CULTURE CELLS . Photochemistry and Photobiology vol. 45 , ( S1 ) 757 - 761 .

( 2008 ) . Role of <i>α</i>9<i>β</i>1 integrin in the regulation of epithelial cell behaviour . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 89 , A8 - A9 .

( 2008 ) . Transductional retargeting of adenovirus-5 to alphavbeta6 integrin . HUMAN GENE THERAPY . vol. 19 , 1102 - 1102 .

( 2007 ) . Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells . NAT CELL BIOL vol. 9 , ( 12 ) 1392 - U92 .

( 2007 ) . Integrin trafficking and its role in cancer metastasis . CANCER METAST REV vol. 26 , ( 3-4 ) 567 - 578 .

( 2007 ) . Use of a Peptide Derived from Foot-and-Mouth Disease Virus for the Noninvasive Imaging of Human Cancer: Generation and Evaluation of 4-[18F]Fluorobenzoyl A20FMDV2 for <i>In vivo</i> Imaging of Integrin αvβ6 Expression with Positron Emission Tomography . Cancer Research vol. 67 , ( 16 ) 7833 - 7840 .

( 2007 ) . HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alpha(v)beta(6) . CANCER RES vol. 67 , ( 11 ) 5275 - 5284 .

( 2007 ) . Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands . J BIOL CHEM vol. 282 , ( 13 ) 9657 - 9665 .

( 2007 ) . Expression of alphavbeta6 supersedes Her2 and triple-negative/basal classification of breast cancer and defines novel subgroups with poor survival: implications for breast cancer classification and treatment . BREAST CANCER RESEARCH AND TREATMENT . vol. 106 , S11 - S11 .

( 2007 ) . Molecular profiling of DCIS: identification of distinct subgroups of potential prognostic importance . BREAST CANCER RESEARCH AND TREATMENT . vol. 106 , S221 - S221 .

( 2006 ) . Cyclooxygenase-2 inhibition suppresses alpha(v)beta(6) integrin-dependent oral squamous carcinoma invasion . CANCER RES vol. 66 , ( 22 ) 10833 - 10842 .

( 2006 ) . 255 INVITED Targeting the invasio-association integrin alphavbeta6 as an anti-carcinoma strategy . European Journal of Cancer Supplements vol. 4 , ( 12 ) 82 - 82 .

( 2006 ) . Functional analysis of normal and DCIS modified breast myoepithelial cells . Breast Cancer Research . vol. 8 ,

( 2006 ) . Integrin expression in human melanoma cell lines: Heterogeneity of vitronectin receptor composition and function . International Journal of Cancer vol. 49 , ( 6 ) 924 - 931 .

( 2006 ) . S100A7 and the basal phenotype in breast cancer . BREAST CANCER RESEARCH AND TREATMENT . vol. 100 , S159 - S159 .

( 2006 ) . Tumor cell migration in three dimensions . METHOD ENZYMOL vol. 406 , 625 - 643 .

( 2006 ) . alpha v beta 6 integrin in wound healing and cancer of the oral cavity . J ORAL PATHOL MED vol. 35 , ( 1 ) 1 - 10 .

( 2005 ) . αvβ6 integrin down-regulates the MMP-13 expression in oral squamous cell carcinoma cells . Experimental Cell Research vol. 309 , ( 2 ) 273 - 283 .

( 2005 ) . Development of a quantitative method to analyse tumour cell invasion in organotypic culture . J PATHOL vol. 205 , ( 4 ) 468 - 475 .

( 2005 ) . Mechanisms of migration and invasion of squamous cell carcinoma in an <i>in vitro</i> model of squamous cell carcinogenesis . BRITISH JOURNAL OF DERMATOLOGY . vol. 152 , 843 - 843 .

( 2005 ) . Migration and invasion mechanisms in an <i>in vitro</i> model of squamous cell carcinogenesis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 124 , A22 - A22 .

( 2004 ) . TNF-alpha regulates epithelial expression of MMP-9 and integrin alpha v beta 6 during tumour promotion. A role for TNF-alpha in keratinocyte migration? . ONCOGENE vol. 23 , ( 41 ) 6954 - 6966 .

( 2004 ) . αv integrins play an important role in myofibroblast differentiation . Wound Repair and Regeneration vol. 12 , ( 4 ) 461 - 470 .

( 2004 ) . The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9 . J BIOL CHEM vol. 279 , ( 25 ) 26533 - 26539 .

( 2004 ) . Modulation of the urokinase-type plasminogen activator receptor by the β6 integrin subunit . Biochemical and Biophysical Research Communications vol. 317 , ( 1 ) 92 - 99 .

( 2004 ) . Attenuated type II TGF‐β receptor signalling in human malignant oral keratinocytes induces a less differentiated and more aggressive phenotype that is associated with metastatic dissemination . International Journal of Cancer vol. 110 , ( 2 ) 170 - 176 .

( 2004 ) . Tumour-derived TGF-β1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells . British Journal of Cancer vol. 90 , ( 4 ) 822 - 832 .

( 2004 ) . Reduction of TSG101 protein has a negative impact on tumor cell growth . International Journal of Cancer vol. 109 , ( 4 ) 541 - 547 .

( 2004 ) . A quantitative method for measuring three-dimensional invasion in vitro using organotypic cultures . BRITISH JOURNAL OF CANCER . vol. 91 , S58 - S58 .

( 2003 ) . Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes . Journal of Cell Science vol. 116 , ( 20 ) 4239 - 4248 .

( 2003 ) . Tumor suppressor p16(INK4a) determines sensitivity of human cells to transformation by cooperating cellular oncogenes . CANCER CELL vol. 4 , ( 4 ) 301 - 310 .

( 2003 ) . Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability . Journal of Cell Science vol. 116 , ( 16 ) 3303 - 3314 .

Zhu G, Reynolds L, Crnogorac-Jurcevic T, Gillett CE, Dublin EA, Marshall JF, Barnes D, D'Arrigo C et al. ( 2003 ) . Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer . ONCOGENE vol. 22 , ( 24 ) 3742 - 3748 .

Zhu G, Reynolds L, Crnogorac-Jurcevic T, Gillett CE, Dublin EA, Marshall JF, Barnes D, D'Arrigo C et al. ( 2003 ) . Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer . Oncogene vol. 22 , ( 24 ) 3742 - 3748 .

( 2003 ) . An <i>in vitro</i> 3D-Model of Invasive Squamous Cell Carcinoma (SCC) Recapitulates <i>in vivo</i> Pathology . Clinical Science vol. 104 , ( s49 ) 28P - 29P .

( 2003 ) . Restoration of e-cadherin function alters morphology of oral squamous carcinoma cells . JOURNAL OF DENTAL RESEARCH . vol. 82 , 485 - 485 .

( 2003 ) . avβ6 integrin interaction with the tgf-β1 latency-associated peptide (lap) . JOURNAL OF DENTAL RESEARCH . vol. 82 , 485 - 485 .

( 2003 ) . b6-integrin cytoplasmic tail: novel intracellular target for inhibiting oral scc invasion . JOURNAL OF DENTAL RESEARCH . vol. 82 , 472 - 472 .

( 2003 ) . β6-integrin cytoplasmic tail:: Novel intracellular target for inhibiting oral SCC invasion . JOURNAL OF DENTAL RESEARCH vol. 82 , B327 - B327 .

( 2002 ) . Differential expression of carcinoembryonic antigen (CEA) splice variants in whole blood of colon cancer patients and healthy volunteers: implication for the detection of circulating colon cancer cells . Oncogene vol. 21 , ( 51 ) 7817 - 7823 .

( 2002 ) . Binding of TGF-β1 latency-associated peptide (LAP) to αvβ6 integrin modulates behaviour of squamous carcinoma cells . British Journal of Cancer vol. 87 , ( 8 ) 859 - 867 .

( 2002 ) . First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous5-fluorouracil/leucovorin . Annals of Oncology vol. 13 , ( 4 ) 566 - 575 .

( 2002 ) . Rapid solid phase synthesis and biodistribution of 18F-labelled linear peptides . European Journal of Nuclear Medicine and Molecular Imaging vol. 29 , ( 6 ) 754 - 759 .

( 2002 ) . Solid phase synthesis of <SUP>18</SUP>F-labelled cyclic peptides . JOURNAL OF NUCLEAR MEDICINE vol. 43 , ( 5 ) Article ARTN 201143 , 365P - 365P .

( 2002 ) . The ß6 integrin subunit C-terminal 11 amino acids are sufficient to promote invasion by squamous cell carcinoma (SCC) cells . BRITISH JOURNAL OF CANCER vol. 86 , S120 - S120 .

( 2001 ) . O-029. αvβ6 integrin promotes invasion of squamous carcinoma cells through upregulation of MMP-9 . Oral Oncology vol. 37 , ( SUPPL. 1 )

( 2001 ) . Expression of the αvβ6 Integrin Promotes Migration and Invasion in Squamous Carcinoma Cells . Journal of Investigative Dermatology vol. 117 , ( 1 ) 67 - 73 .

( 2001 ) . αvβ6 Integrin Upregulates Matrix Metalloproteinase 9 and Promotes Migration of Normal Oral Keratinocytes . Journal of Investigative Dermatology vol. 116 , ( 6 ) 898 - 904 .

( 2001 ) . αvβ6integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9 . International Journal of Cancer vol. 92 , ( 5 ) 641 - 650 .

( 2001 ) . Adenovirus type 5 uptake by lung adenocarcinoma cells in culture correlates with Ad5 fibre binding is mediated by ?v?1 integrin and can be modulated by changes in ?1 integrin function . The Journal of Gene Medicine vol. 3 , ( 6 ) 550 - 559 .

( 2001 ) . Mechanisms of adhesion-dependence in mouse melanocyte-derived cell lines . BRITISH JOURNAL OF CANCER vol. 85 , 82 - 82 .

( 2001 ) . The Protrusive Phase and Full Development of Integrin-Dependent Adhesions in Colon Epithelial Cells Require FAK- and ERKMediated Actin Spike Formation: Deregulation in Cancer Cells . Neoplasia vol. 3 , ( 3 ) 215 - 226 .

( 2001 ) . The terminal 11a.a. cytoplasmic tail of the β6 integrin subunit is essential for the promotion of αVβ6-dependent invasion . BRITISH JOURNAL OF CANCER vol. 85 , 22 - 22 .

( 2001 ) . αvβ6-dependent upregulation of MMP-9 promotes keratinocyte migration . JOURNAL OF DENTAL RESEARCH vol. 80 , ( 4 ) 1155 - 1155 .

( 2000 ) . The Integrins α3β1 and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells . Journal of Biological Chemistry vol. 275 , ( 45 ) 35264 - 35275 .

( 2000 ) . Photo-Induced Inactivation of Protein Kinase Cα by Dequalinium Inhibits Motility of Murine Melanoma Cells . Molecular Pharmacology vol. 58 , ( 4 ) 729 - 737 .

( 2000 ) . Functional interaction between E-cadherin and αv-containing integrins in carcinoma cells . Journal of Cell Science vol. 113 , ( 3 ) 425 - 437 .

( 2000 ) . In vivo therapy of malignant melanoma by means of antagonists of αv integrins . International Journal of Cancer vol. 87 , ( 5 ) 716 - 723 .

( 1999 ) . The intracellular hyaluronan receptor RHAMM/IHABP interacts with microtubules and actin filaments . Journal of Cell Science vol. 112 , ( 22 ) 3943 - 3954 .

( 1999 ) . Chemokines induce the cellular migration of MCF-7 human breast carcinoma cells: Subpopulations of tumour cells display positive and negative chemotaxis and differential in vivo growth potentials . Clinical &amp; Experimental Metastasis vol. 17 , ( 5 ) 389 - 396 .

( 1999 ) . The Role of Adhesion in Metastasis: . 345 - 365 .

( 1998 ) . Fibronectin is chemotactic for CT 26 colon carcinoma cells: sub-lines selected for increased chemotaxis to fibronectin display decreased tumorigenicity and lung colonization . Clinical &amp; Experimental Metastasis vol. 16 , ( 8 ) 683 - 691 .

( 1998 ) . The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells . Journal of Cell Science vol. 111 , ( 12 ) 1685 - 1694 .

( 1998 ) . Hypoxia facilitates tumour cell detachment by reducing expression of surface adhesion molecules and adhesion to extracellular matrices without loss of cell viability . British Journal of Cancer vol. 77 , ( 11 ) 1799 - 1805 .

( 1998 ) . Comparative analysis of integrins in vitro and in vivo in uveal and cutaneous melanomas . British Journal of Cancer vol. 77 , ( 4 ) 522 - 529 .

( 1998 ) . Expression of αv integrins and vitronectin receptor identity in breast cancer cells . British Journal of Cancer vol. 77 , ( 4 ) 530 - 536 .

( 1997 ) . Activation status and function of the VLA-4 (α4β1) integrin expressed on human melanoma cell lines . International Journal of Cancer vol. 73 , ( 2 ) 264 - 270 .

( 1997 ) . Modulation of human stromelysin 3 promoter activity and gene expression by human breast cancer cells . International Journal of Cancer vol. 73 , ( 2 ) 290 - 296 .

( 1997 ) . Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16 . Journal of Virology vol. 71 , ( 8 ) 6204 - 6207 .

( 1997 ) . Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression . International Journal of Cancer vol. 71 , ( 2 ) 267 - 274 .

( 1996 ) . The role of αv-integrins in tumour progression and metastasis . Seminars in Cancer Biology vol. 7 , ( 3 ) 129 - 138 .

( 1996 ) . Identification by differential display of annexin-VI, a gene differentially expressed during melanoma progression . CANCER RESEARCH vol. 56 , ( 17 ) 3855 - 3858 .

( 1995 ) . αvβ1 is a receptor for vitronectin and fibrinogen, and acts with α5β1 to mediate spreading on fibronectin . Journal of Cell Science vol. 108 , ( 3 ) 1227 - 1238 .

( 1992 ) . Cell and tissue responses of a murine tumour to phthalocyanine-mediated photodynamic therapy . European Journal of Cancer vol. 28 , ( 1 ) 42 - 46 .

( 1991 ) . Cell adhesion receptor expression during melanoma progression and metastasis . CANCER AND METASTASIS REVIEW vol. 10 , ( 2 ) 115 - 128 .

( 1991 ) . INFLUENCE OF TUMOR-DERIVED INTERLEUKIN-1 ON MELANOMA-ENDOTHELIAL CELL-INTERACTIONS INVITRO . CANCER RESEARCH vol. 51 , ( 18 ) 4768 - 4775 .

( 1990 ) . Effect of Sulfonation on the Cell and Tissue Distribution of the Photosensitizer Aluminum Phthalocyanine . Cancer Research vol. 50 , ( 15 ) 4533 - 4538 .

( 1989 ) . Effect of tumour location on selective uptake and retention of phthalocyanines . Cancer Letters vol. 44 , ( 1 ) 73 - 77 .

( 1988 ) . TISSUE UPTAKE, DISTRIBUTION, AND POTENCY OF THE PHOTOACTIVATABLE DYE CHLOROALUMINUM SULFONATED PHTHALOCYANINE IN MICE BEARING TRANSPLANTABLE TUMORS . CANCER RESEARCH vol. 48 , ( 11 ) 3040 - 3044 .

( 1985 ) . CHANGES IN SURFACE-STRUCTURE AND CONCANAVALIN A-BINDING CAPACITY OF UROTHELIUM IN THE MOUSE BLADDER AFTER WHOLE-BODY NEUTRON-IRRADIATION . SCANNING ELECTRON MICROSCOPY vol. 1985 , 1603 - 1614 .