Skip to main content
Research

Publications: DR Mangesh Thorat

Sinha A, Jurrius P, Schelt A-SV, Darwish O, Annio G, Shifa B, Peterson Z, Jeffery H et al. ( 2025 ) . Abstract P4-05-19: Magnetic Resonance Elastography: A Novel Imaging tool to predict response in patients undergoing Neo-Adjuvant Chemotherapy for Breast Cancer . Clinical Cancer Research vol. 31 , ( 12_Supplement )
Thorat MA ( 2025 ) . An aspirin a day keeps cancer at bay . BJC Reports vol. 3 , ( 1 ) Article 23 ,
Tondare A, Thorat MA ( 2025 ) . De-escalation of axillary interventions in the management of breast cancer patients following neoadjuvant systemic treatment . Translational Breast Cancer Research vol. 6 , 14 - 14 .
Thorat MA ( 2025 ) . COMETgazing - interesting insights, lessons for clinical practice and a call for more precision using the biomarkerSCOPE . Oncotarget vol. 16 , ( 1 ) 138 - 139 .
Sinha AP, Jurrius P, van Schelt A-S, Darwish O, Shifa B, Annio G, Peterson Z, Jeffery H et al. ( 2025 ) . Tumor Biomechanics Quantified Using MR Elastography to Predict Response to Neoadjuvant Chemotherapy in Individuals with Breast Cancer . Radiology: Imaging Cancer vol. 7 , ( 2 ) Article e240138 ,
Irakleidis F, Warren M, Sidlauskas K, Hall P, Hawkesford K, Phillips M, Thorat M, Angelis V ( 2025 ) . P437: Discrepancies in the assessment of oestrogen and progesterone receptor status using immunohistochemistry and OncotypeDX; reclassification to triple negative breast cancer and implications in treatment . The Breast vol. 80 , Article 104249 , 104249 - 104249 .
Agha R, Mathew G, Rashid R, Kerwan A, Al-Jabir A, Sohrabi C, Franchi T, Nicola M et al. ( 2025 ) . Revised Strengthening the reporting of cohort, cross-sectional and case-control studies in surgery (STROCSS) Guideline: An update for the age of Artificial Intelligence . Premier Journal of Science
Madathil JP, Sureka S, Spyrou I, Denoiseux C, Thorat MA ( 2024 ) . Axillary imaging to assess response to neoadjuvant chemotherapy in breast cancer and guide de-escalation of axillary surgery: a single-institution retrospective study . European Journal of Surgical Oncology vol. 50 , Article 109426 , 109426 - 109426 .
Thorat MA ( 2024 ) . Differences in Sentinel Node Biopsy and Targeted Axillary Dissection Following Neoadjuvant Chemotherapy . JAMA Oncology vol. 10 , ( 12 ) 1728 - 1728 .
Chougle Q, Hamed H, Thorat M, Kothari A ( 2024 ) . MENOPRE – A Randomised Controlled trial comparing the use of Meshes versus No meshes in pre-pectoral direct to implant immediate breast reconstruction . European Journal of Surgical Oncology vol. 50 , Article 108882 , 108882 - 108882 .
Thorat MA, Cuzick J, Chan AT ( 2024 ) . Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer . JAMA vol. 332 , ( 13 ) 1111 - 1111 .
Aggarwal A, Badve SS, Cuzick J, Madabhushi A, Thorat MA ( 2024 ) . 171P A computational pathology collagen signature predictive of tamoxifen benefit in ductal carcinoma in situ: Results from a cohort within the UK/ANZ DCIS randomized trial . Annals of Oncology vol. 35 , S284 - S284 .
Li H, Aggarwal A, Toro P, Fu P, Badve SS, Cuzick J, Madabhushi A, Thorat MA ( 2024 ) . A prognostic and predictive computational pathology immune signature for ductal carcinoma in situ: retrospective results from a cohort within the UK/ANZ DCIS trial . The Lancet Digital Health vol. 6 , ( 8 ) e562 - e569 .
Garg N, Thorat MA ( 2024 ) . A nomogram for predicting axillary node pathologic complete response—A necessary component of the path toward true axillary de‐escalation but needs a clear definition of the research question and a robust study design . Cancer vol. 130 , ( 20 ) 3549 - 3550 .
Sinha A, Peterson Z, Shifa B, Jeffery H, Jurrius P, Allen S, Lee E, Azmat M et al. ( 2024 ) . Cerenkov luminescence imaging and flexible autoradiography for specimen margin assessment during breast-conserving cancer surgery . Radiology Advances vol. 1 , ( 2 ) Article umae015 ,
Garg N, Thorat M, Hamed H, Kothari A ( 2024 ) . Abstract PO3-23-07: Evaluation of the role of axillary ultrasound to estimate axillary nodal burden to guide de-escalation of upfront axillary surgery in node positive early breast cancer patients . Cancer Research vol. 84 , ( 9_Supplement )
Sinha A, Jeffery H, Peterson Z, Shifa B, Jurrius P, Allen S, Lee E, Azmat M et al. ( 2024 ) . Cerenkov Luminescence Imaging and flexible autoradiography – A first-in-human novel imaging study for intra-operative margin assessment in women undergoing breast-conserving surgery for cancer . European Journal of Surgical Oncology vol. 50 , Article 108143 , 108143 - 108143 .
Sinha A, Jurrius P, Darwish O, Shifa B, Peterson Z, Jeffery H, Walsh K, Metafa A et al. ( 2024 ) . Predicting response to neoadjuvant chemotherapy in breast cancer by biomechanics quantified with magnetic resonance elastography . European Journal of Surgical Oncology vol. 50 , Article 108145 , 108145 - 108145 .
Garg N, Thorat MA, Kothari AS ( 2024 ) . The SOUND Randomized Clinical Trial Results . JAMA Oncology vol. 10 , ( 5 ) 676 - 676 .
Sinha A, Jeffery H, Peterson Z, Shifa B, Jurrius P, Allen S, Lee E, Azmat M et al. ( 2024 ) . Cerenkov Luminescence Imaging and Flexible AutoRadiography – a first-in-human novel imaging study for intra-operative margin assessment in women undergoing breast-conserving surgery for cancer . European Journal of Cancer vol. 200 , Article 113758 , 113758 - 113758 .
Garg N, Thorat M, Kothari A ( 2024 ) . Do the results of the SOUND trial necessitate a paradigm shift in our approach to axillary staging in patients undergoing a mastectomy for DCIS? . European Journal of Cancer vol. 200 , Article 113791 , 113791 - 113791 .
Sinha A, Jurrius P, Darwish O, Shifa B, Peterson Z, Jeffery H, Welsh K, Metafa A et al. ( 2024 ) . Predicting response to neoadjuvant chemotherapy in breast cancer by biomechanics quantified with Magnetic Resonance Elastography . European Journal of Cancer vol. 200 , Article 113817 , 113817 - 113817 .
Chougle Q, Chandra A, Thorat M, Hamed H, Kothari A ( 2024 ) . Audit on the use of core biopsy imprint cytology in a one stop Breast clinic . European Journal of Surgical Oncology vol. 50 , ( 2 ) Article 107468 , 107468 - 107468 .
Mathew G, Sohrabi C, Franchi T, Nicola M, Kerwan A, Agha R ( 2023 ) . Preferred reporting of case series in surgery (PROCESS) 2023 guidelines . International Journal of Surgery
Garg N, Thorat MA ( 2023 ) . Letter to the Editor: Cost‐Efficacy Analysis of Use of Frozen Section Histology for Margin Assessment During Breast Conservation Surgery in Breast Cancer Patients . World Journal of Surgery vol. 47 , ( 12 ) 3451 - 3452 .
Thorat MA ( 2023 ) . Multiclonality of ER expression in DCIS - Implications for clinical practice and future research . Oncotarget vol. 14 , ( 1 ) 719 - 720 .
McDermott KT, Noake C, Wolff R, Bauld L, Espina C, Foucaud J, Steindorf K, Thorat MA et al. ( 2023 ) . Digital interventions to moderate physical inactivity and/or nutrition in young people: a Cancer Prevention Europe overview of systematic reviews . Frontiers in Digital Health vol. 5 , Article 1185586 ,
McDermott KT, Noake C, Wolff R, Espina C, Foucaud J, Steindorf K, Schüz J, Thorat MA et al. ( 2023 ) . Digital interventions to moderate alcohol consumption in young people: a Cancer Prevention Europe overview of systematic reviews . Frontiers in Digital Health vol. 5 , Article 1178407 ,
Sohrabi C, Mathew G, Maria N, Kerwan A, Franchi T, Agha RA ( 2023 ) . The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines . International Journal of Surgery vol. 109 , ( 5 ) 1136 - 1140 .
Garg N, Thorat MA, Deshpande A ( 2023 ) . P236 Immediate breast reconstruction as a day case procedure and impact of COVID-19 pandemic . The Breast vol. 68 , S109 - S109 .
Li H, Madabhushi A, Badve S, Cuzick J, Thorat MA ( 2023 ) . P240 Computerized Quantification of Tumor Infiltrating Lymphocyte (TIL) as a prognostic and predictive factor in ductal carcinoma in situ: Results from the UK/ANZ DCIS randomized trial . The Breast vol. 68 , S111 - S111 .
Garg N, Thorat MA ( 2023 ) . HER2 expression should be routinely evaluated in DCIS to avoid under or overtreatment! . Oncoscience vol. 10 , 1 - 3 .
Li H, Madabhushi A, Badve S, Cuzick J, Thorat MA ( 2023 ) . Computerized Quantification of Tumor Infiltrating Lymphocyte (TIL) as a prognostic and predictive factor in ductal carcinoma in situ: Results from the UK/ANZ DCIS randomized trial . BREAST . vol. 68 , S111 - S111 .
Garg N, Thorat MA, Deshpande A ( 2023 ) . Immediate breast reconstruction as a day case procedure and impact of COVID-19 pandemic . BREAST . vol. 68 , S109 - S109 .
Mathew G, Agha R, Albrecht J, Goel P, Mukherjee I, Pai P, D'Cruz AK, Nixon IJ et al. ( 2021 ) . STROCSS 2021: Strengthening the reporting of cohort, cross-sectional and case-control studies in surgery . Annals of Medicine and Surgery vol. 72 , Article 103026 , 103026 - 103026 .
( 2021 ) . Mammographic density, endocrine therapy and breast cancer risk: a prognostic and predictive biomarker review . Cochrane Database of Systematic Reviews vol. 2021 , ( 10 )
Hall LH, Thorneloe R, Rodriguez-Lopez R, Grice A, Thorat MA, Bradbury K, Kamble MW, Okoli GN et al. ( 2021 ) . Delivering brief physical activity interventions in primary care: a systematic review . British Journal of General Practice vol. 72 , ( 716 ) e209 - e216 .
Thorat MA, Levey PM, Jones JL, Pinder SE, Bundred NJ, Fentiman IS, Cuzick J ( 2021 ) . Prognostic and Predictive Value of HER2 Expression in Ductal Carcinoma <i>In Situ</i>: Results from the UK/ANZ DCIS Randomized Trial . Clinical Cancer Research vol. 27 , ( 19 ) 5317 - 5324 .
Lloyd KE, Hall LH, Ziegler L, Smith SG, Adamson V, Ainsworth S, Akerlund M, Baker I et al. ( 2021 ) . Breast cancer worry in higher-risk women offered preventive therapy: a UK multicentre prospective study . Breast Cancer Research and Treatment vol. 188 , ( 3 ) 703 - 712 .
Thorat MA, Levey PM, Jones JL, Pinder SE, Bundred NJ, Fentiman IS, Cuzick J ( 2021 ) . Prognostic Value of ER and PgR Expression and the Impact of Multi-clonal Expression for Recurrence in Ductal Carcinoma <i>in situ</i>: Results from the UK/ANZ DCIS Trial . Clinical Cancer Research vol. 27 , ( 10 ) 2861 - 2867 .
Li H, Fu P, Toro P, Madabhushi A, Thorat M ( 2021 ) . Computerized Quantification of Tumor Infiltrating Lymphocyte (TIL) Density on H&E Images is Associated with Recurrence Risk in Ductal Carcinoma in Situ (DCIS) . LABORATORY INVESTIGATION . vol. 101 , 121 - 122 .
Agha RA, Sohrabi C, Mathew G, Franchi T, Kerwan A, O’Neill N, Thoma A, Beamish AJ et al. ( 2020 ) . The PROCESS 2020 Guideline: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) Guidelines . International Journal of Surgery vol. 84 , 231 - 235 .
Agha RA, Franchi T, Sohrabi C, Mathew G, Kerwan A, Thoma A, Beamish AJ, Noureldin A et al. ( 2020 ) . The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines . International Journal of Surgery vol. 84 , 226 - 230 .
Thorat MA, Balasubramanian R ( 2020 ) . Breast cancer prevention in high-risk women . Best Practice &amp; Research Clinical Obstetrics &amp; Gynaecology vol. 65 , 18 - 31 .
Li H, Bera K, Gilmore H, Zhang Z, Cuzick J, Thorat MA, Madabhushi A ( 2020 ) . Abstract P5-06-15: Computer extracted features of nuclear shape, orientation disorder and texture from H&amp;E Whole slide images are associated with disease-free survival in ductal carcinoma in situ (DCIS) . Cancer Research . vol. 80 ,
Agha R, Abdall-Razak A, Crossley E, Dowlut N, Iosifidis C, Mathew G, Beamishaj, Bashashati M et al. ( 2019 ) . STROCSS 2019 Guideline: Strengthening the reporting of cohort studies in surgery . International Journal of Surgery vol. 72 , 156 - 165 .
Li H, Whitney J, Bera K, Gilmore H, Thorat MA, Badve S, Madabhushi A ( 2019 ) . Quantitative nuclear histomorphometric features are predictive of Oncotype DX risk categories in ductal carcinoma in situ: preliminary findings . Breast Cancer Research vol. 21 , ( 1 ) Article 114 ,
Dowling RJO, Sparano JA, Goodwin PJ, Bidard F-C, Cescon DW, Chandarlapaty S, Deasy JO, Dowsett M et al. ( 2019 ) . Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions . JNCI Cancer Spectrum vol. 3 , ( 4 ) Article pkz049 ,
Dowling RJO, Kalinsky K, Hayes DF, Bidard F-C, Cescon DW, Chandarlapaty S, Deasy JO, Dowsett M et al. ( 2019 ) . Toronto Workshop on Late Recurrence in Estrogen Receptor–Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations . JNCI Cancer Spectrum vol. 3 , ( 4 ) Article pkz050 ,
Espina C, Bauld L, Bonanni B, Brenner H, Brown K, Dillner J, Kampman E, Nilbert M et al. ( 2019 ) . WITHDRAWAL—Administrative Duplicate Publication: The essential role of prevention in reducing the cancer burden in Europe: a commentary from Cancer Prevention Europe . Tumori Journal vol. 106 , ( 5 ) NP2 - NP4 .
Thorat MA ( 2019 ) . Liquid biopsy for cancer diagnosis and screening – The promise and challenges . Annals of Clinical Biochemistry: International Journal of Laboratory Medicine vol. 56 , ( 4 ) 420 - 423 .
Allen N, Allen M, Ahmed K, Gomm J, Nelan R, Nagano A, Chelala C, Gadaleta E et al. ( 2019 ) . Abstract P5-18-08: Defining molecular signatures to personalise management of patients with early breast cancer . Cancer Research . vol. 79 ,
Thorneloe RJ, Horne R, Side L, Wolf MS, Smith SG, Adamson V, Ainsworth S, Akerlund M et al. ( 2019 ) . Beliefs About Medication and Uptake of Preventive Therapy in Women at Increased Risk of Breast Cancer: Results From a Multicenter Prospective Study . Clinical Breast Cancer vol. 19 , ( 1 ) e116 - e126 .
Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP, Zhu H, Alsawadi A et al. ( 2018 ) . The PROCESS 2018 statement: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) guidelines . International Journal of Surgery vol. 60 , 279 - 282 .
Agha RA, Borrelli MR, Farwana R, Koshy K, Fowler AJ, Orgill DP, Zhu H, Alsawadi A et al. ( 2018 ) . The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines . International Journal of Surgery vol. 60 , 132 - 136 .
( 2018 ) . Mammographic density, endocrine therapy and breast cancer risk: a prognostic and predictive biomarker review . Cochrane Database of Systematic Reviews
Thorat MA ( 2018 ) . Aspirin . Reference Module in Biomedical Sciences , Elsevier
Thorat MA ( 2018 ) . Aspirin and Cancer . Encyclopedia of Cancer Third Edition Volumes 1 3 , vol. 1 ,
Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP, Afifi R, Al-Ahmadi R et al. ( 2017 ) . Erratum to “Erratum to “The SCARE guidelines: Consensus-based surgical case report guidelines” [Int. J. Surg. 34 (2016) 180–186]” [Int. J. Surg. 36 (2016) 396] . International Journal of Surgery vol. 47 , 151 - 151 .
Agha RA, Borrelli MR, Vella-Baldacchino M, Thavayogan R, Orgill DP, Pagano D, Pai PS, Basu S et al. ( 2017 ) . The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery . International Journal of Surgery vol. 46 , 198 - 202 .
Thorat MA, Cuzick J ( 2017 ) . Preventing invasive breast cancer using endocrine therapy . The Breast vol. 34 , S47 - S54 .
Cuzick J ( 2017 ) . Preventing invasive breast cancer using endocrine therapy . The Breast vol. 32 , S7 - S8 .
Thorat MA, Wagner S, Jones LJ, Levey PM, Bulka K, Hoff R, Sangale Z, Flake DD et al. ( 2017 ) . Abstract P1-09-06: Prognostic and predictive relevance of cell cycle progression (CCP) score in ductal carcinoma <i>in situ</i>: Results from the UK/ANZ DCIS trial . Cancer Research . vol. 77 ,
Oke A, Knox J, Tan J, Aigret B, Schmid P, Coleman RE, Cuzick J, Thorat MA ( 2017 ) . Barriers to recruitment from primary care into a trial in secondary care settings: experience from the feasibility study of IBIS-3 trial . TRIALS . vol. 18 ,
Ussi AE, Rebolj M, Thorat MA, Bietrix F, Fauvel A, Hajdúch M, Hill C, Walker I et al. ( 2016 ) . Assessing opportunities for coordinated <scp>R</scp>&amp;<scp>D</scp> in early cancer detection and management in <scp>E</scp>urope . International Journal of Cancer vol. 140 , ( 7 ) 1700 - 1701 .
Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP, Afifi R, Al-Ahmadi R et al. ( 2016 ) . Erratum to “The SCARE guidelines: Consensus-based surgical case report guidelines” [Int. J. Surg. 34 (2016) 180–186] . International Journal of Surgery vol. 36 , 396 - 396 .
Agha RA, Fowler AJ, Rajmohan S, Barai I, Orgill DP, Afifi R, Alahmadi R, Albrecht J et al. ( 2016 ) . Preferred reporting of case series in surgery; the PROCESS guidelines . International Journal of Surgery vol. 36 , 319 - 323 .
Agha RA, Fowler AJ, Saeta A, Barai I, Rajmohan S, Orgill DP, Afifi R, Al-Ahmadi R et al. ( 2016 ) . The SCARE Statement: Consensus-based surgical case report guidelines . International Journal of Surgery vol. 34 , 180 - 186 .
Guerrieri-Gonzaga A, Sestak I, Lazzeroni M, Serrano D, Rotmensz N, Cazzaniga M, Varricchio C, Thorat MA et al. ( 2016 ) . Abstract 1788: Benefit of low-dose tamoxifen in a large, single-institution cohort of high-risk ER-positive DCIS . Cancer Research . vol. 76 , 1788 - 1788 .
Thorat MA ( 2016 ) . Individualised benefit–harm balance of aspirin as primary prevention measure – a good proof-of-concept, but could have been better… . BMC Medicine vol. 14 , ( 1 ) Article 101 ,
Thorat MA ( 2016 ) . A major flaw in “Awareness of breast cancer and barriers to breast screening uptake in Bangladesh: A population based survey” . Maturitas vol. 88 , 45 - 45 .
Thorat MA, Wagner S, Jones LJ, Levey PM, Bulka K, Hoff R, Sangale Z, II FDD et al. ( 2016 ) . Prognostic and predictive relevance of HER2 status in ductal carcinoma in situ: Results from the UK/ANZ DCIS trial . CANCER RESEARCH . vol. 76 ,
Thorat MA, Jones LJ, Levey PM, Elia G, Evagora CA, Bundred NJ, Fentiman IS, Forbes JF et al. ( 2016 ) . Prognostic role and impact of multi-clonal ER and PgR expression in ductal carcinoma in situ: Results from the UK/ANZ DCIS trial . CANCER RESEARCH . vol. 76 ,
Cuzick J, Cuschieri K, Denton K, Hopkins M, Thorat MA, Wright C, Cubie H, Moore C et al. ( 2015 ) . Performance of the Xpert HPV assay in women attending for cervical screening . Papillomavirus Research vol. 1 , 32 - 37 .
DeCensi A ( 2015 ) . Barriers to preventive therapy for breast and other major cancers and strategies to improve uptake . ecancermedicalscience vol. 9 ,
Cuzick J, Sestak I, Thorat MA ( 2015 ) . Impact of preventive therapy on the risk of breast cancer among women with benign breast disease . The Breast vol. 24 , S51 - S55 .
Thorat MA ( 2015 ) . Sentinel lymph node assessment in breast cancer patients receiving neo‐adjuvant chemotherapy: to biopsy before or after? . International Journal of Cancer vol. 138 , ( 2 ) 267 - 270 .
Cuzick J, Thorat M ( 2015 ) . PG 6.02 Preventing invasive breast cancer in women at high risk based on benign/in situ pathology . The Breast . vol. 24 , S11 - S11 .
Thorat MA, Cuzick J ( 2015 ) . Reply to the letter to the editor ‘The harms of low-dose aspirin prophylaxis are overstated’ by P. Elwood and G. Morgan . Annals of Oncology vol. 26 , ( 2 ) 442 - 443 .
Cuzick J, Thorat MA, Bosetti C, Brown PH, Burn J, Cook NR, Ford LG, Jacobs EJ et al. ( 2015 ) . Estimates of benefits and harms of prophylactic use of aspirin in the general population . Annals of Oncology vol. 26 , ( 1 ) 47 - 57 .
Cuzick J, Thorat MA, Bosetti C, Brown PH, Burn J, Cook NR, Ford LG, Jacobs EJ et al. ( 2015 ) . Estimates of benefits and harms of prophylactic use of aspirin in the general population . Annals of oncology : official journal of the European Society for Medical Oncology vol. 26 , ( 1 ) 47 - 57 .
Pathmarajah P, Shah K, Taghipour K, Ramachandra S, Thorat MA, Chaudhry Z, Patkar V, Peters F et al. ( 2015 ) . Letrozole-induced necrotising leukocytoclastic small vessel vasculitis: First report of a case in the UK . International Journal of Surgery Case Reports vol. 16 , 77 - 80 .
Cuzick J, Thorat MA ( 2015 ) . PSA testing for prostate cancer screening – Authors' reply . The Lancet Oncology vol. 16 , ( 1 ) e3 - e3 .
Thorat MA, Cuzick J ( 2014 ) . Prophylactic use of aspirin: systematic review of harms and approaches to mitigation in the general population . European Journal of Epidemiology vol. 30 , ( 1 ) 5 - 18 .
Cuzick J, Thorat MA, Andriole G, Brawley OW, Brown PH, Culig Z, Eeles RA, Ford LG et al. ( 2014 ) . Prevention and early detection of prostate cancer . The Lancet Oncology vol. 15 , ( 11 ) e484 - e492 .
Vasiljević N, Ahmad AS, Thorat MA, Fisher G, Berney DM, Møller H, Foster CS, Cuzick J et al. ( 2014 ) . DNA methylation gene-based models indicating independent poor outcome in prostate cancer . BMC Cancer vol. 14 , ( 1 ) Article 655 ,
Thorat MA, Cuzick J ( 2013 ) . Role of Aspirin in Cancer Prevention . Current Oncology Reports vol. 15 , ( 6 ) 533 - 540 .
Gökmen-Polar Y, Thorat MA, Sojitra P, Saxena R, Badve S ( 2013 ) . FOXP3 expression and nodal metastasis of breast cancer . Cellular Oncology vol. 36 , ( 5 ) 405 - 409 .
Sainsbury R, Loddo M, Proctor I, Stoeber K, Williams G, Thorat M, Cuzick J ( 2012 ) . Abstract PD04-08: Cell cycle algorithm correlates with grade of DCIS and p53 status, allows elimination of ‘intermediate grade’ disease and gives clinically meanignful information . Cancer Research . vol. 72 ,
Vasiljević N, Ahmad AS, Beesley C, Thorat MA, Fisher G, Berney DM, Møller H, Yu Y et al. ( 2012 ) . Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer . Prostate Cancer and Prostatic Diseases vol. 16 , ( 1 ) 35 - 40 .
Cheol Kim D, Thorat MA, Lee MR, Cho SH, Vasiljević N, Scibior-Bentkowska D, Wu K, Ahmad AS et al. ( 2012 ) . Quantitative DNA methylation and recurrence of breast cancer: A study of 30 candidate genes . Cancer Biomarkers vol. 11 , ( 2-3 ) 75 - 88 .
Thorat MA ( 2012 ) . Tackling breast cancer in India . The Lancet vol. 379 , ( 9834 ) 2340 - 2341 .
Duchnowska R, Jassem J, Goswami CP, Gokmen-Polar Y, Li L, Thorat MA, Flores N, Hua E et al. ( 2012 ) . 13-gene signature to predict rapid development of brain metastases in patients with HER2-positive advanced breast cancer . Journal of Clinical Oncology vol. 30 , ( 15_suppl ) 505 - 505 .
Duchnowska R, Jassem J, Goswami CP, Gokmen-Polar Y, Li L, Thorat MA, Flores N, Hua E et al. ( 2012 ) . 13-gene signature to predict rapid development of brain metastases in patients with HER2-positive advanced breast cancer . JOURNAL OF CLINICAL ONCOLOGY . vol. 30 ,
Schneider BP, Radovich M, Hancock B, Kassem N, Sledge G, Nielsen KV, Thorat M, Mehta R et al. ( 2012 ) . <i>VEGFA</i> Amplification/Deletion in Human Breast Tumors . MODERN PATHOLOGY . vol. 25 , 65A - 65A .
Duchnowska R, Jassem J, Szutowicz E, Biernat W, Jankowski T, Och W, Staszkiewicz R, Chudzik M et al. ( 2011 ) . RAD51 and brain metastases (BM) in patients (pts) with HER2+ breast cancer . Journal of Clinical Oncology . vol. 29 , 634 - 634 .
Duchnowska R, Jassem J, Szutowicz E, Biernat W, Jankowski T, Och W, Staszkiewicz R, Chudzik M et al. ( 2011 ) . RAD51 and brain metastases (BM) in patients (pts) with HER2+ breast cancer . Journal of clinical oncology : official journal of the American Society of Clinical Oncology . vol. 29 ,
( 2011 ) . Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing . DIS MARKERS vol. 30 , ( 4 ) 151 - 161 .
Sojitra PM, Thorat M, Jain RK, Mehta R, Badve S ( 2011 ) . Regulatory T-Cells in Breast Cancer Sentinel Nodes: FOXP3 Expression Analysis . MODERN PATHOLOGY . vol. 24 , 64A - 64A .
Ademuyiwa FO, Miller A, O’Connor T, Edge SB, Thorat MA, Sledge GW, Levine E, Badve S ( 2011 ) . The effects of oncotype DX recurrence scores on chemotherapy utilization in a multi-institutional breast cancer cohort . Breast Cancer Research and Treatment vol. 126 , ( 3 ) 797 - 802 .
McCune K, Mehta R, Thorat MA, Badve S, Nakshatri H ( 2010 ) . Loss of ERα and FOXA1 expression in a progression model of luminal type breast cancer: Insights from PyMT transgenic mouse model . Oncology Reports vol. 24 , ( 5 ) 1233 - 1239 .
S. Vaidya J, Baldassarre G, A. Thorat M, Massarut S ( 2010 ) . Role of Glucocorticoids in Breast Cancer . Current Pharmaceutical Design vol. 16 , ( 32 ) 3593 - 3600 .
Thorat MA, Thorat PM, Vaidya HJ, Vaidya JS ( 2010 ) . Analysis of temporal trends in the BMJ archive . BMJ vol. 341 , ( oct21 2 ) c3306 - c3306 .
Nakshatri ( 2010 ) . Loss of ERα and FOXA1 expression in a progression model of luminal type breast cancer: Insights from PyMT transgenic mouse model . Oncology Reports vol. 24 , ( 5 )
Appaiah H, Bhat-Nakshatri P, Mehta R, Thorat M, Badve S, Nakshatri H ( 2010 ) . ITF2 is a target of CXCR4 in MDA-MB-231 breast cancer cells and is associated with reduced survival in estrogen receptor-negative breast cancer . CANCER BIOL THER vol. 10 , ( 6 ) 600 - 614 .
Schneider BP, Radovich M, Hancock BA, Kassem N, Vance GH, Sledge GW, Nielsen KV, Müller S et al. ( 2010 ) . <i>VEGFA</i> amplification/deletion in human breast tumors . Journal of Clinical Oncology . vol. 28 , e21017 - e21017 .
Badve SS, Li L, Thorat MA, Gagnon RC, Ellis CE, O'Shaughnessy J, Blackwell KL, Baselga J et al. ( 2010 ) . Differential gene expression analysis and correlation with outcome in HER2-positive metastatic breast cancer treated with HER2-targeted therapy . Journal of Clinical Oncology . vol. 28 , 1036 - 1036 .
Ademuyiwa FO, Miller A, Edge SB, Thorat MA, Sledge GW, Badve SS ( 2010 ) . The effects of Oncotype DX recurrence scores on chemotherapy receipt in a multi-institutional breast cancer cohort . Journal of Clinical Oncology . vol. 28 , 669 - 669 .
Badve S, Collins NR, Bhat-Nakshatri P, Turbin D, Leung S, Thorat M, Dunn SE, Geistlinger TR et al. ( 2010 ) . Subcellular Localization of Activated AKT in Estrogen Receptor- and Progesterone Receptor-Expressing Breast Cancers Potential Clinical Implications . AM J PATHOL vol. 176 , ( 5 ) 2139 - 2149 .
Ademuyiwa FO, Thorat MA, Jain RK, Nakshatri H, Badve S ( 2010 ) . Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores . Modern Pathology vol. 23 , ( 2 ) 270 - 275 .
Gökmen-Polar Y, Mehta R, Tuzmen S, Mousses S, Thorat MA, Sanders KL, Turbin D, Leung S et al. ( 2010 ) . Differential subcellular expression of protein kinase C betaII in breast cancer: correlation with breast cancer subtypes . Breast Cancer Research and Treatment vol. 124 , ( 2 ) 327 - 335 .
McCune K, Bhat-Nakshatri P, Thorat MA, Nephew KP, Badve S, Nakshatri H ( 2010 ) . Prognosis of Hormone-Dependent Breast Cancers: Implications of the Presence of Dysfunctional Transcriptional Networks Activated by Insulin via the Immune Transcription Factor T-bet . Cancer Research vol. 70 , ( 2 ) 685 - 696 .
Gokmen-Polar Y, Mehta R, Tuzmen S, Mousses S, Thorat MA, Sanders KL, Turbin D, Leung S et al. ( 2010 ) . Differential subcellular expression of protein kinase C betaII in breast cancer: correlation with breast cancer subtypes . Breast Cancer Res Treat. vol. 124 , ( 2 ) 327 - 335 .
Jain RK, Thorat MA, Mehta R, Polar Y, Morimiya A, Sweeney C, Beck S, Ulbright TM et al. ( 2010 ) . Gene Expression Profiles of Classical and Spermatocytic Seminoma . MODERN PATHOLOGY . vol. 23 , 198A - 198A .
Mantovani A ( 2010 ) . Preface .
Resetkova E, Reis-Filho JS, Jain RK, Mehta R, Thorat MA, Nakshatri H, Badve S ( 2009 ) . Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment . Breast Cancer Research and Treatment vol. 123 , ( 1 ) 97 - 108 .
Badve S, Shen C, Thorat M, Li L, Gagnon R, Koehler M, Ellis C, O'Shaughnessy J et al. ( 2009 ) . 5BA Identification of gene expression profiles that predict response to HER2-targeted therapy . European Journal of Cancer Supplements . vol. 7 , 5 - 5 .
Al-Azzawi HH, Pitt HA, Swartz-Basile DA, Wang S, Dalbec KM, Thorat MA, Zyromski NJ ( 2009 ) . Obesity downregulates innate and adaptive immunity genes in the pancreatic cancer microenvironment . Journal of the American College of Surgeons . vol. 209 , S118 - S119 .
Ademuyiwa FO, Thorat M, Nakshatri H, Badve S ( 2009 ) . Correlation of FOXA1 expression with Oncotype Dx recurrence scores . Journal of Clinical Oncology . vol. 27 , 11058 - 11058 .
Hammoud ZT, Badve S, Zhao Q, Li L, Saxena R, Thorat MA, Morimiya A, Rieger KM et al. ( 2009 ) . Differential gene expression profiling of esophageal adenocarcinoma . The Journal of Thoracic and Cardiovascular Surgery vol. 137 , ( 4 ) 829 - 834 .
Thorat MA, Mehrotra S, Morimiya A, Badve S ( 2009 ) . COX-2 Expression Does Not Correlate with Microvessel Density in Breast Cancer . Pathobiology vol. 76 , ( 1 ) 39 - 44 .
McCune KR, Bhat-Nakshatri P, Thorat M, Badve S, Nakshatri H ( 2009 ) . Control of luminal type A intrinsic subtype enriched transcription factor network by insulin: implications of diabetes on breast cancer classification . Cancer Research . vol. 69 , 3029 - 3029 .
Duchnowska R, Jassem J, Shen C, Thorat M, Li L, Morimiya A, Zhao Q, Biernat W et al. ( 2009 ) . Molecular characteristics of matched brain metastasis (BM) versus the primary breast cancer (PBC) . Cancer Research . vol. 69 , 2028 - 2028 .
McCune K, Thorat M, Badve S, Nakshatri H ( 2009 ) . A transgenic model for dietary intervention/chemoprevention strategies for metastatic breast cancer . ANNALS OF SURGICAL ONCOLOGY . vol. 16 , 45 - 45 .
Thorat MA ( 2009 ) . Comment on \Dynamic response to heat - a novel physical characteristic of breast cancer\ . International Journal of Surgery vol. 7 , ( 2 ) 173 - 173 .
McCune KR, Bhat-Nakshatri P, Thorat M, Badve S, Nakshatri H ( 2009 ) . Control of luminal type A intrinsic subtype enriched transcription factor network by insulin: implications of diabetes on breast cancer classification . CANCER RESEARCH . vol. 69 , 213S - 214S .
Thorat MA, Ademuyiwa FO, Nakshatri H, Badve S ( 2009 ) . Expression of FOXA1, Estrogen Receptor Associated Transcription Factor, Correlates with Oncotype Dx Recurrence Score . LABORATORY INVESTIGATION . vol. 89 , 72A - 72A .
Duchnowska R, Jassem J, Shen C, Thorat M, Li L, Morimiya A, Zhao Q, Biernat W et al. ( 2009 ) . Molecular characteristics of matched brain metastasis (BM) versus the primary breast cancer (PBC) . CANCER RESEARCH . vol. 69 , 164S - 164S .
Al-Azzawi H, Swartz-Basile D, Wang S, Dalbec K, Thorat M, Pitt H, Zyromski N ( 2009 ) . Obesity promotes differential gene expression in pancreatic cancer . CANCER RESEARCH . vol. 69 ,
Thorat MA, Turbin D, Morimiya A, Leung S, Zhang Q, Jeng M, Huntsman DG, Nakshatri H et al. ( 2008 ) . Amplified in breast cancer 1 expression in breast cancer . Histopathology vol. 53 , ( 6 ) 634 - 641 .
Thorat MA, Rangole A, Nadkarni MS, Parmar V, Badwe RA ( 2008 ) . Revision surgery for breast cancer . Cancer vol. 113 , ( S8 ) 2347 - 2352 .
Thorat MA, Rangole A, Nadkarni MS, Parmar V, Badwe RA ( 2008 ) . Revision surgery for breast cancer: single-institution experience . Cancer vol. 113 , ( 8 Suppl ) 2347 - 2352 .
Thorat MA, Badve S ( 2008 ) . Estrogen- and progesterone-receptor status in breast cancer: Immunohistochemistry and quantitative reverse transcription-polymerase chain reaction assays show equivalency . American Journal of Hematology Oncology vol. 7 , ( 9 )
( 2008 ) . Five Genetic Variants Associated with Prostate Cancer . New England Journal of Medicine vol. 358 , ( 25 ) 2738 - 2741 .
Duchnowska R, Jassem J, Thorat MA, Morimiya A, Sledge GW, Li L, Biernat W, Szczylik C et al. ( 2008 ) . Gene expression analysis for prediction of early brain metastasis (BM) in HER2-positive (HER2+) breast cancer patients (pts) . Journal of Clinical Oncology . vol. 26 , 1019 - 1019 .
Duchnowska R, Jassem J, Thorat MA, Morimiya A, Sledge GW, Li L, Biernat W, Szczylik C et al. ( 2008 ) . Gene expression analysis for prediction of early brain metastasis (BM) in HER2-positive (HER2+) breast cancer patients (pts) . J Clin Oncol . vol. 26 ,
Thorat MA, Saxena R, Badve SS ( 2008 ) . Regulatory T cells (T-Regs) in breast cancer sentinel nodes (SN): FOXP3 expression analysis . Journal of Clinical Oncology . vol. 26 , 22175 - 22175 .
Thorat MA, Saxena R, Badve SS ( 2008 ) . Regulatory T cells (T-Regs) in breast cancer sentinel nodes (SN): FOXP3 expression analysis . J Clin Oncol . vol. 26 ,
Thorat MA ( 2008 ) . What caused the decline in US breast cancer incidence? . Nature Clinical Practice Oncology vol. 5 , ( 6 ) 314 - 315 .
Thorat MA, Thornton H ( 2008 ) . MRI breast screening . The Lancet vol. 371 , ( 9622 ) 1415 - 1415 .
HAN-COCK B, RADOVICH M, BADVE S, THORAT M, AZZOUZ F, SCHNEIDER B ( 2008 ) . Association of single nucleotide polymorphisms in angiogenesis genes with expression of VEGF and VEGFR-2 in breast carcinoma . Conference: Proceedings of the American Association for Cancer Research Annual Meeting vol. 49 ,
Badve S, Thorat M, Reis-Filho J ( 2008 ) . Cytoplasmic expression of ALDH1 correlates with breast cancer subtypes . HISTOPATHOLOGY . vol. 53 , 26 - 26 .
Resetkova E, Thorat M, Badve S ( 2008 ) . Expression of ALDH1 (putative cancer stem cell marker) does not correlate with response to neoadjuvant chemotherapy (NACT) in breast carcinoma . HISTOPATHOLOGY . vol. 53 , 59 - 60 .
Marchio C, Thorat M, Morimiya A, Savage K, Nakshatri H, Reis-Filho J, Badve S ( 2008 ) . FOXA1: A prognostic and luminal subtype a marker in breast cancer . MODERN PATHOLOGY . vol. 21 , 45A - 45A .
Janssens ACJW, van Duijn CM ( 2008 ) . Five genetic variants associated with prostate cancer . NEW ENGLAND JOURNAL OF MEDICINE vol. 358 , ( 25 ) 2739 - 2739 .
Thorat MA, Morimiya A, Mehrotra S, Konger R, Badve SS ( 2008 ) . Prostanoid receptor EP1 expression in breast cancer . Modern Pathology vol. 21 , ( 1 ) 15 - 21 .
Thorat MA ( 2007 ) . Should we undertake an MRI breast screening trial? . The Lancet vol. 370 , ( 9603 ) 1902 - 1902 .
Thorat MA, Marchio C, Morimiya A, Savage K, Nakshatri H, Reis-Filho JS, Badve S ( 2007 ) . Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis . Journal of Clinical Pathology vol. 61 , ( 3 ) 327 - 332 .
Badve S, Turbin D, Thorat MA, Morimiya A, Nielsen TO, Perou CM, Dunn S, Huntsman DG et al. ( 2007 ) . FOXA1 Expression in Breast Cancer—Correlation with Luminal Subtype A and Survival . Clinical Cancer Research vol. 13 , ( 15 ) 4415 - 4421 .
Thorat MA ( 2007 ) . Gene-signature-based prognostic tools in breast cancer: not yet . The Lancet vol. 369 , ( 9571 ) 1428 - 1428 .
Thorat MA, Badve S ( 2007 ) . Prognostic factors in invasive breast carcinoma: Do new molecular techniques/profiling add significantly to traditional histological factors? . Current Diagnostic Pathology vol. 13 , ( 2 ) 116 - 125 .
Basu S, Nair N, Thorat M, Shet T ( 2007 ) . Uptake characteristics of FDG in multiple juvenile cellular fibroadenomata of the breast - FDG-PET and histopathologic correlation . CLIN NUCL MED vol. 32 , ( 3 ) 203 - 204 .
Thorat MA, Parmar V, Nadkarni MS, Badwe RA ( 2007 ) . Radiation Therapy for Ductal Carcinoma In Situ: Is It Really Worth It? . Journal of Clinical Oncology vol. 25 , ( 4 ) 461 - 462 .
Thorat M, Morimiya A, Sledge G, Badve S ( 2007 ) . Characterization of estrogen receptor positive breast cancers: gene expression analysis of archived tumours . BREAST CANCER RESEARCH AND TREATMENT . vol. 106 , S243 - S243 .
Thorat M ( 2006 ) . Tuning into the genetic orchestra using microarrays: limitations of DNA microarrays in clinical practice . Nature Clinical Practice Oncology vol. 3 , ( 12 ) E1 - E1 .
Thorat MA ( 2006 ) . Medical research in India . The Lancet vol. 368 , ( 9536 ) 643 - 644 .
Badwe RA, D’cruz AK, Mistry RC, Tongaonkar HB, Shastri S, Thorat MA ( 2006 ) . Developing Countries: An Evolving Opportunity for Oncologic Research . World Journal of Surgery vol. 30 , ( 7 ) 1173 - 1176 .
Thorat M ( 2006 ) . Trastuzumab for early breast cancer . LANCET vol. 367 , ( 9505 ) 108 - 108 .
Thorat MA ( 2006 ) . Are there distinct lymphatic flow patterns in the Breast? . Medical Hypotheses vol. 66 , ( 5 ) 1040 - 1041 .
Thorat MA, Datar RH, Joshi NN ( 2006 ) . Cancer immunotherapeutics: Raising the ante . NATIONAL MEDICAL JOURNAL OF INDIA vol. 19 , ( 3 ) 140 - 150 .
( 2005 ) . Autoantibodies in Prostate Cancer . New England Journal of Medicine vol. 353 , ( 26 ) 2815 - 2817 .
Badwe RA, Thorat MA ( 2005 ) . Does primary tumor location have prognostic significance in operable breast cancer? . Nature Clinical Practice Oncology vol. 2 , ( 8 ) 396 - 397 .
Thorat MA, Badwe RA ( 2005 ) . Autoantibodies in prostate cancer . NEW ENGLAND JOURNAL OF MEDICINE vol. 353 , ( 26 ) 2816 - 2816 .
Thorat MA ( 2005 ) . Herceptin in early breast cancer: a call for judicious use . National Medical Journal of India vol. 18 , ( 6 ) 315 - 317 .
Thorat MA, Thorat PM ( 2005 ) . Privately versus publicly managed primary healthcare . NATIONAL MEDICAL JOURNAL OF INDIA vol. 18 , ( 5 ) 274 - 275 .
Thorat M ( 2004 ) . Optimum cancer care - an unaffordable goal? . LANCET ONCOL vol. 5 , ( 9 ) 530 - 530 .
( 2003 ) . Sentinel-Node Biopsy in Breast Cancer . New England Journal of Medicine vol. 349 , ( 20 ) 1968 - 1971 .
Badwe RA, Thorat MA, Parmar VV ( 2003 ) . Sentinel-node biopsy in breast cancer . NEW ENGLAND JOURNAL OF MEDICINE vol. 349 , ( 20 ) 1968 - 1968 .
( 2002 ) . Radical and Simple Mastectomy . New England Journal of Medicine vol. 347 , ( 26 ) 2170 - 2171 .
Somlo G ( 2002 ) . Radical and simple mastectomy . The New England journal of medicine vol. 347 , ( 26 ) 2170 - 2171 .
Sinha A, Jurrius P, Darwish O, Shida B, Peterson Z, Jeffery H, Welsh K, Metafa A et al. . Predicting response to neoadjuvant chemotherapy in breast cancer by biomechanics quantified with Magnetic Resonance Elastography . ISMRM Annual Meeting . Conference: 2024 ISMRM & ISMRT Annual Meeting from: 04/05/2024 to: 09/05/2024 ,