Publications: DR Dianne Cooper
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Henriques Schneider A, Cecconello C, Bu W, Imbert PRC et al.
(
2025
)
.
Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis
.
EMBO Molecular Medicine
vol.
17
,
(
5
)
1153
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1183
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Fu H, Vuononvirta J, Fanti S, Bonacina F, D’Amati A, Wang G, Poobalasingam T, Fankhaenel M et al.
(
2025
)
.
Publisher Correction: The glucose transporter 2 regulates CD8+ T cell function via environment sensing
.
Nature Metabolism
vol.
7
,
(
3
)
634
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634
.
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Schneider AH, Cecconello C, Bu W, Imbert PRC et al.
(
2025
)
.
Formyl-peptide receptor type 2 activation mitigates secondary organ damage in inflammatory arthritis
.
Blacksell IA, Vismara M, Lim CM, Dell’Osso B, Pallanti S, Hollander E, Vendruscolo M, D’Addario C et al.
(
2024
)
.
Immuno-moodulin is Differentially Expressed in T Cells and Plasma in Obsessive-Compulsive Disorder Patients
.
Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L et al.
(
2024
)
.
Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues
.
EMBO Reports
vol.
25
,
(
9
)
3842
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3869
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Hussain MT, Austin-Williams S, Wright TD, Dhawan UK, Pinto AL, Cooper D, Norling LV
(
2024
)
.
β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis
.
International Journal of Molecular Sciences
vol.
25
,
(
9
)
4756
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4756
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Fu H, Vuononvirta J, Fanti S, Bonacina F, D’Amati A, Wang G, Poobalasingam T, Fankhaenel M et al.
(
2023
)
.
The glucose transporter 2 regulates CD8+ T cell function via environment sensing
.
Nature Metabolism
vol.
5
,
(
11
)
1969
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1985
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Sabatucci A, Girella A, Di Bartolomeo M, Pucci M, Vismara M, Benatti B, Blacksell IA, Cooper D et al.
(
2023
)
.
A possible role for G-quadruplexes formation and DNA methylation at IMOOD gene promoter in Obsessive Compulsive Disorder
.
Advances in Biological Regulation
vol.
89
,
Article
100976
,
100976
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100976
.
Norling LV, Cooper D
(
2023
)
.
Being old and female is an inflammatory combination
.
Journal of Leukocyte Biology
vol.
114
,
(
4
)
299
-
300
.
D'Acquisto F, D'Addario C, Cooper D, Pallanti S, Blacksell I
(
2023
)
.
Peripheral control of psychiatric disorders: Focus on OCD. Are we there yet?
.
Comprehensive Psychiatry
vol.
123
,
Article
152388
,
152388
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152388
.
Krautter F, Hussain MT, Zhi Z, Lezama DR, Manning JE, Brown E, Marigliano N, Raucci F et al.
(
2022
)
.
Galectin-9: A novel promoter of atherosclerosis progression
.
Atherosclerosis
vol.
363
,
57
-
68
.
Poston RN, Chughtai J, Ujkaj D, Louis H, Leake DS, Cooper D
(
2022
)
.
Monocytic Cell Adhesion to Oxidised Ligands: Relevance to Cardiovascular Disease
.
Biomedicines
vol.
10
,
(
12
)
3083
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3083
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Hamilton A, Rizzo R, Brod S, Ono M, Perretti M, Cooper D, D'Acquisto F
(
2022
)
.
The immunomodulatory effects of social isolation in mice are linked to temperature control
.
Brain, Behavior, and Immunity
vol.
102
,
179
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194
.
Law HL, Cooper D
(
2022
)
.
Methods for Assessing the Effects of Galectins on Leukocyte Trafficking and Clearance
.
Methods in Molecular Biology
,
Springer US
Iqbal AJ, Krautter F, Blacksell IA, Wright RD, Austin‐Williams SN, Voisin M, Hussain MT, Law HL et al.
(
2021
)
.
Galectin‐9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin‐dependent manner
.
The FASEB Journal
vol.
36
,
(
1
)
Chen J, Norling LV, Garrido Mesa J, Silva MDP, Burton SE, Reutelingsperger C, Perretti M, Cooper D
(
2021
)
.
Annexin A1 attenuates cardiac diastolic dysfunction in mice with inflammatory arthritis
.
Proceedings of the National Academy of Sciences
vol.
118
,
(
38
)
Article
e2020385118
,
Hamilton A, Rizzo R, Brod S, Ono M, Perretti M, Cooper D, D’Acquisto F
(
2021
)
.
The Immunomodulatory Effects of Social Isolation in Mice are Linked to Temperature Control
.
Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS et al.
(
2021
)
.
Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation
.
Immunity
vol.
54
,
(
9
)
1989
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2004.e9
.
Oggero S, de Gaetano M, Marcone S, Fitzsimons S, Pinto AL, Ikramova D, Barry M, Burke D et al.
(
2021
)
.
Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
.
Journal of Extracellular Vesicles
vol.
10
,
(
6
)
Article
12084
,
Chen J, Norling LV, Cooper D
(
2021
)
.
Cardiac Dysfunction in Rheumatoid Arthritis: The Role of Inflammation
.
Cells
vol.
10
,
(
4
)
881
-
881
.
Gilbert SG, Krautter F, Cooper D, Chimen M, Iqbal AJ, Spill F
(
2020
)
.
CASTLE: cell adhesion with supervised training and learning environment
.
Journal of Physics D: Applied Physics
vol.
53
,
(
42
)
424002
-
424002
.
Gilbert SG, Krautter F, Cooper D, Chimen M, Iqbal AJ, Spill F
(
2020
)
.
CASTLE: Cell Adhesion with Supervised Training and Learning Environment
.
Law HL, Wright RD, Iqbal AJ, Norling LV, Cooper D
(
2020
)
.
A Pro-resolving Role for Galectin-1 in Acute Inflammation
.
Frontiers in Pharmacology
vol.
11
,
Article
274
,
Oggero S, de Gaetano M, Marcone S, Barry M, Montero-Melendez T, Cooper D, Norling LV, Brennan EP et al.
(
2019
)
.
Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque responses
.
Goldberg R, Scotta C, Cooper D, Nissim-Eliraz E, Nir E, Tasker S, Irving PM, Sanderson J et al.
(
2019
)
.
Correction of Defective T-Regulatory Cells From Patients With Crohn’s Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α
.
Gastroenterology
vol.
156
,
(
6
)
1775
-
1787
.
Oggero S, Van Gorp R, Cooper D, Norling L, Schurgers L, Reutelinsperger C, Perretti M
(
2019
)
.
Monocyte and not Neutrophil derived microvesicles are able to activate endothelial cells and smooth muscle cells and to enhance recruitment of PMN in a Flow Chamber based assay
.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
.
vol.
49
,
198
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199
.
Gittens BR, Bodkin JV, Nourshargh S, Perretti M, Cooper D
(
2017
)
.
Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation
.
The Journal of Immunology
vol.
198
,
(
11
)
4458
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4469
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Piovezan AP, Batisti AP, Benevides MLACS, Turnes BL, Martins DF, Kanis L, Duarte ECW, Cavalheiro AJ et al.
(
2017
)
.
Hydroalcoholic crude extract of Casearia sylvestris Sw. reduces chronic post-ischemic pain by activation of pro-resolving pathways
.
Journal of Ethnopharmacology
vol.
204
,
179
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188
.
Boardman DA, Philippeos C, Fruhwirth GO, Ibrahim MAA, Hannen RF, Cooper D, Marelli-Berg FM, Watt FM et al.
(
2017
)
.
Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection
.
American Journal of Transplantation
vol.
17
,
(
4
)
931
-
943
.
Goldberg R, Scotta C, Cooper D, Eliraz E, Nir E, Irving P, Sanderson J, Shpigel N et al.
(
2017
)
.
OP028 Gut specific regulatory T cells – a new frontier for Crohn's disease therapy
.
Journal of Crohn's and Colitis
vol.
11
,
(
suppl_1
)
S17
-
S17
.
Perretti M, Cooper D, Dalli J, Norling LV
(
2017
)
.
Immune resolution mechanisms in inflammatory arthritis
.
Nature Reviews Rheumatology
vol.
13
,
(
2
)
87
-
99
.
Goldberg R, Scotta C, Cooper D, Irving P, Sanderson J, Shpigel N, Marelli-Berg F, Lombardi G et al.
(
2017
)
.
GUT SPECIFIC REGULATORY T CELLS - A NEW FRONTIER FOR CROHN'S DISEASE THERAPY
.
GUT
.
vol.
66
,
A35
-
A36
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Goldberg R, Scotta C, Cooper D, Eliraz E, Nir E, Irving P, Sanderson J, Shpigel N et al.
(
2017
)
.
Gut specific regulatory T cells - a new frontier for Crohn's disease therapy
.
JOURNAL OF CROHNS & COLITIS
.
vol.
11
,
S17
-
S17
.
Wright RD, Souza PR, Flak MB, Thedchanamoorthy P, Norling LV, Cooper D
(
2016
)
.
Galectin-3–null mice display defective neutrophil clearance during acute inflammation
.
Journal of Leukocyte Biology
vol.
101
,
(
3
)
717
-
726
.
Iqbal AJ, Barrett TJ, Taylor L, McNeill E, Manmadhan A, Recio C, Carmineri A, Brodermann MH et al.
(
2016
)
.
Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo
.
eLife
vol.
5
,
Article
e15190
,
Barrett TJ, Iqbal AJ, Taylor L, McNeill E, Manmadhan A, White GE, Cooper D, DiDonato JA et al.
(
2016
)
.
Abstract 575: Acute Exposure to Apolipoprotein AI Inhibits Macrophage and Macrophage Chemotaxis i\n <i>n vitro</i>\n and Recruitment i\n <i>n vivo</i>
.
Arteriosclerosis, Thrombosis, and Vascular Biology
vol.
36
,
(
suppl_1
)
Holloway PM, Durrenberger PF, Trutschl M, Cvek U, Cooper D, Orr AW, Perretti M, Getting SJ et al.
(
2015
)
.
Both MC\n <sub>1</sub>\n and MC\n <sub>3</sub>\n Receptors Provide Protection From Cerebral Ischemia-Reperfusion–Induced Neutrophil Recruitment
.
Arteriosclerosis, Thrombosis, and Vascular Biology
vol.
35
,
(
9
)
1936
-
1944
.
Komarowska I, Coe D, Wang G, Haas R, Mauro C, Kishore M, Cooper D, Nadkarni S et al.
(
2015
)
.
Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release
.
Immunity
vol.
42
,
(
6
)
1087
-
1099
.
Wright RD, Cooper D
(
2014
)
.
Glycobiology of leukocyte trafficking in inflammation
.
Glycobiology
vol.
24
,
(
12
)
1242
-
1251
.
Curciarello R, Steele A, Cooper D, MacDonald TT, Kruidenier L, Kudo T
(
2014
)
.
The Role of Galectin-1 and Galectin-3 in the Mucosal Immune Response to Citrobacter rodentium Infection
.
PLoS ONE
vol.
9
,
(
9
)
e107933
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e107933
.
Gittens BR, Wright RD, Cooper D
(
2014
)
.
Methods for Assessing the Effects of Galectins on Leukocyte Trafficking
.
133
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151
.
Ahmed TJ, Kaneva MK, Pitzalis C, Cooper D, Perretti M
(
2014
)
.
Resolution of inflammation: examples of peptidergic players and pathways
.
Drug Discovery Today
vol.
19
,
(
8
)
1166
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1171
.
Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ et al.
(
2014
)
.
Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation
.
Nature Communications
vol.
5
,
(
1
)
Article
3436
,
Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ et al.
(
2014
)
.
Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation
.
IMMUNOLOGY
vol.
143
,
124
-
124
.
Iqbal AJ, Cooper D, Vugler A, Gittens BR, Moore A, Perretti M
(
2013
)
.
Endogenous Galectin-1 Exerts Tonic Inhibition on Experimental Arthritis
.
The Journal of Immunology
vol.
191
,
(
1
)
171
-
177
.
Gittens B, Perretti M, Cooper D
(
2013
)
.
Investigating Novel Roles for Exogenous and Endogenous Galectin‐3 in Controlling Vascular Inflammation
.
The FASEB Journal
.
vol.
27
,
Rhodes DH, Pini M, Castellanos KJ, Montero‐Melendez T, Cooper D, Perretti M, Fantuzzi G
(
2013
)
.
Adipose tissue‐specific modulation of galectin expression in lean and obese mice: Evidence for regulatory function
.
Obesity
vol.
21
,
(
2
)
310
-
319
.
Pang J, Rhodes DH, Pini M, Akasheh RT, Castellanos KJ, Cabay RJ, Cooper D, Perretti M et al.
(
2013
)
.
Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice
.
PLoS ONE
vol.
8
,
(
2
)
e57915
-
e57915
.
Cooper D
(
2012
)
.
A Therapeutic Role for Galectins in Acute Inflammation?
.
325
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342
.
Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D et al.
(
2012
)
.
The peritoneal tumour microenvironment of high‐grade serous ovarian cancer
.
The Journal of Pathology
vol.
227
,
(
2
)
136
-
145
.
Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M
(
2012
)
.
A role for Galectin‐9 in neutrophil trafficking
.
The FASEB Journal
.
vol.
26
,
Cooper D, Iqbal AJ, Gittens BR, Cervone C, Perretti M
(
2012
)
.
The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?
.
Annals of the New York Academy of Sciences
vol.
1253
,
(
1
)
181
-
192
.
Nadkarni S, Cooper D, Brancaleone V, Bena S, Perretti M
(
2011
)
.
Activation of the Annexin A1 Pathway Underlies the Protective Effects Exerted by Estrogen in Polymorphonuclear Leukocytes
.
Arteriosclerosis, Thrombosis, and Vascular Biology
vol.
31
,
(
11
)
2749
-
2759
.
Roviezzo F, Brancaleone V, De Gruttola L, Vellecco V, Bucci M, D'Agostino B, Cooper D, Sorrentino R et al.
(
2011
)
.
Sphingosine-1-Phosphate Modulates Vascular Permeability and Cell Recruitment in Acute Inflammation In Vivo
.
J PHARMACOL EXP THER
vol.
337
,
(
3
)
830
-
837
.
Iqbal AJ, Sampaio ALF, Maione F, Greco KV, Niki T, Hirashima M, Perretti M, Cooper D
(
2011
)
.
Endogenous Galectin-1 and Acute Inflammation Emerging Notion of a Galectin-9 Pro-Resolving Effect
.
AM J PATHOL
vol.
178
,
(
3
)
1201
-
1209
.
Iqbal AJ, Cooper D, Vugler AD, Moore A, Perretti M
(
2011
)
.
ENDOGENOUS GALECTIN-1 INHIBITS EXPERIMENTAL ARTHRITIS: A POTENTIAL SWEET THERAPEUTIC TARGET?
.
INFLAMMATION RESEARCH
.
vol.
60
,
186
-
187
.
Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M
(
2011
)
.
GALECTIN-9: SWEETENING LEUKOCYTE RECRUITMENT
.
INFLAMMATION RESEARCH
.
vol.
60
,
87
-
88
.
Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F
(
2010
)
.
Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature
.
BLOOD
vol.
116
,
(
20
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4288
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4296
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Canaider
(
2010
)
.
Human RCAN3 gene expression and cell growth in endothelial cells
.
International Journal of Molecular Medicine
vol.
26
,
(
6
)
Yazid S, Leoni G, Getting SJ, Cooper D, Solito E, Perretti M, Flower RJ
(
2010
)
.
Antiallergic Cromones Inhibit Neutrophil Recruitment Onto Vascular Endothelium via Annexin-A1 Mobilization
.
ARTERIOSCL THROM VAS
vol.
30
,
(
9
)
1718
-
U103
.
Norling LV, Leoni G, Cooper D, Perretti M
(
2010
)
.
Cell Adhesion Molecules
.
Fundamentals of Inflammation
,
Cambridge University Press
Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M
(
2010
)
.
A role for Galectin-9 in neutrophil trafficking
.
FASEB JOURNAL
vol.
24
,
Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M
(
2010
)
.
Human RCAN3 gene expression and cell growth in endothelial cells
.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
vol.
26
,
(
6
)
913
-
918
.
Cooper D, Ilarregui JM, Pesoa SA, Croci DO, Perretti M, Rabinovich GA
(
2010
)
.
MULTIPLE FUNCTIONAL TARGETS OF THE IMMUNOREGULATORY ACTIVITY OF GALECTIN-1: CONTROL OF IMMUNE CELL TRAFFICKING, DENDRITIC CELL PHYSIOLOGY, AND T-CELL FATE
.
vol.
480
,
Hunter C, Kadakia TB, Cooper D, Perretti M, Schwartz RC, Brown SB
(
2010
)
.
Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands
.
The Scientific World JOURNAL
vol.
10
,
1580
-
1596
.
Perretti M, Iqbal A, Cooper D
(
2009
)
.
Galectin 1 Controls Cell Trafficking in Inflammation
.
GLYCOBIOLOGY
.
vol.
19
,
1310
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1310
.
Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M et al.
(
2009
)
.
Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
.
Nature
vol.
461
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7268
)
1287
-
1291
.
Norling LV, Perretti M, Cooper D
(
2009
)
.
Endogenous galectins and the control of the host inflammatory response
.
J ENDOCRINOL
vol.
201
,
(
2
)
169
-
184
.
Dalli J, Norling LV, Renshaw D, Cooper D, Leung K-Y, Perretti M
(
2008
)
.
Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles
.
Blood
vol.
112
,
(
6
)
2512
-
2519
.
Cooper D, Norling LV, Perretti M
(
2008
)
.
Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow
.
J LEUKOCYTE BIOL
vol.
83
,
(
6
)
1459
-
1466
.
Norling LV, Sampaio ALF, Cooper D, Perretti M
(
2008
)
.
Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking
.
FASEB J
vol.
22
,
(
3
)
682
-
690
.
Urquhart P, Rosignoli G, Cooper D, Motterlini R, Perretti M
(
2007
)
.
Carbon Monoxide-Releasing Molecules Modulate Leukocyte-Endothelial Interactions under Flow
.
The Journal of Pharmacology and Experimental Therapeutics
vol.
321
,
(
2
)
656
-
662
.
Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ, Solito E, Perretti M
(
2006
)
.
Antiflammin-2 activates the human formyl-peptide receptor like 1
.
THESCIENTIFICWORLDJO
vol.
6
,
1375
-
1384
.
Petnehazy T, Cooper D, Stokes KY, Russell J, Wood KC, Granger DN
(
2006
)
.
Angiotensin II type 1 receptors and the intestinal microvascular dysfunction induced by ischemia and reperfusion
.
AM J PHYSIOL-GASTR L
vol.
290
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(
6
)
G1203
-
G1210
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Norling LV, Cooper D, Perretti M
(
2006
)
.
Endogenous Galectn‐1 inhibits lymphocyte‐endothelial cell interactions as determined by small interference RNA
.
The FASEB Journal
.
vol.
20
,
Hayhoe RPG, Cooper D, Perretti M
(
2006
)
.
The anti‐adhesive effects of annexin 1 on neutrophil‐endothelial interactions under flow
.
The FASEB Journal
.
vol.
20
,
Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D, Perretti M
(
2006
)
.
Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement
.
Blood
vol.
107
,
(
5
)
2123
-
2130
.
Gil CD, Cooper D, Rosignoli G, Perretti M, Oliani SM
(
2006
)
.
Inflammation-induced modulation of cellular galectin-1 and-3 expression in a model of rat peritonitis
.
INFLAMM RES
vol.
55
,
(
3
)
99
-
107
.
Urquhart P, Cooper D, Motterlini R, Perretti M
(
2006
)
.
CO-releasing molecules modulate leukocyte/endothelial cell adhesion: under static and flow studies
.
FASEB JOURNAL
.
vol.
20
,
A1321
-
A1321
.
Tailor A, Cooper D, Granger DN
(
2005
)
.
Platelet-Vessel wall interactions in the microcirculation
.
MICROCIRCULATION
vol.
12
,
(
3
)
275
-
285
.
Cooper D, Hayhoe RPG, Perretti M
(
2005
)
.
Effect of annexin 1 in an in vitro model of human neutrophil-endothelial interaction under flow
.
FASEB JOURNAL
.
vol.
19
,
A1522
-
A1522
.
Cooper D, Perretti M
(
2005
)
.
Galectin-1 inhibits neutrophil rolling in a carbohydrate-dependent manner
.
FASEB JOURNAL
.
vol.
19
,
A1512
-
A1512
.
Ishikawa M, Cooper D, Arumugam TV, Zhang TH, Nanda A, Granger DN
(
2004
)
.
Platelet-leukocyte-endothelial cell interactions after middle cerebral artery occlusion and reperfusion
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J CEREBR BLOOD F MET
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