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Research

Publications: DR Manuela Lahne

Sarkar H, Lahne M, Nair N, Moosajee M ( 2023 ) . Oxidative and Endoplasmic Reticulum Stress Represent Novel Therapeutic Targets for Choroideremia . Antioxidants vol. 12 , ( 9 )
Uttley K, Papanastasiou AS, Lahne M, Brisbane JM, MacDonald RB, Bickmore WA, Bhatia S ( 2023 ) . Unique activities of two overlapping PAX6 retinal enhancers . Life Science Alliance vol. 6 , ( 11 )
Lahne M, Hyde DR ( 2023 ) . Live Cell Imaging of Dynamic Processes in Adult Zebrafish Retinal Cross-Section Cultures . Axon Regeneration , vol. 2636 , Springer Nature
Abdolkarimi D, Cunha DL, Lahne1 M, Moosajee M ( 2022 ) . PAX6 disease models for aniridia . Indian Journal of Ophthalmology vol. 70 , ( 12 ) 4119 - 4129 .
Hentig J, Cloghessy K, Lahne M, Jung YJ, Petersen RA, Morris AC, Hyde DR ( 2021 ) . Zebrafish Blunt-Force TBI Induces Heterogenous Injury Pathologies That Mimic Human TBI and Responds with Sonic Hedgehog-Dependent Cell Proliferation across the Neuroaxis . Biomedicines vol. 9 , ( 8 )
Lahne M, Brecker M, Jones SE, Hyde DR ( 2021 ) . The Regenerating Adult Zebrafish Retina Recapitulates Developmental Fate Specification Programs . Frontiers in Cell and Developmental Biology vol. 8 ,
Hoang T, Wang J, Boyd P, Wang F, Santiago C, Jiang L, Yoo S, Lahne M et al. ( 2020 ) . Gene regulatory networks controlling vertebrate retinal regeneration . Science vol. 370 , ( 6519 )
Lahne M, Nagashima M, Hyde DR, Hitchcock PF ( 2020 ) . Reprogramming Müller Glia to Regenerate Retinal Neurons . Annual Review of Vision Science vol. 6 , ( 1 ) 1 - 23 .
Chambers JM, Poureetezadi SJ, Addiego A, Lahne M, Wingert RA ( 2018 ) . ppargc1a controls nephron segmentation during zebrafish embryonic kidney ontogeny . eLife vol. 7 ,
Lahne M, Piekos SM, O'Neill J, Ackerman KM, Hyde DR ( 2018 ) . Photo-regulation of rod precursor cell proliferation . Experimental Eye Research vol. 178 , 148 - 159 .
Gorsuch RA, Lahne M, Yarka CE, Petravick ME, Li J, Hyde DR ( 2017 ) . Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a . Experimental Eye Research vol. 161 , 174 - 192 .
Lahne M, Gorsuch RA, Nelson CM, Hyde DR ( 2017 ) . Culture of Adult Transgenic Zebrafish Retinal Explants for Live-cell Imaging by Multiphoton Microscopy . Journal of Visualized Experiments ( 120 )
Lahne M, Gorsuch RA, Nelson CM, Hyde DR ( 2017 ) . Culture of adult transgenic zebrafish retinal explants for live-cell imaging by multiphoton microscopy . Journal of Visualized Experiments ( 120 )
Lahne M, Hyde DR ( 2017 ) . Live-cell imaging: new avenues to investigate retinal regeneration . Neural Regeneration Research vol. 12 , ( 8 ) 1210 - 1219 .
Lahne M, Li J, Marton RM, Hyde DR ( 2015 ) . Actin-Cytoskeleton- and Rock-Mediated INM Are Required for Photoreceptor Regeneration in the Adult Zebrafish Retina . Journal of Neuroscience vol. 35 , ( 47 ) 15612 - 15634 .
Lahne M, Hyde DR ( 2016 ) . Interkinetic Nuclear Migration in the Regenerating Retina . Advances in Experimental Medicine and Biology . vol. 854 , 587 - 593 .
Conner C, Ackerman KM, Lahne M, Hobgood JS, Hyde DR ( 2014 ) . Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells . Journal of Neuroscience vol. 34 , ( 43 ) 14403 - 14419 .
Lahne M, Gale JE ( 2010 ) . Damage-induced cell-cell communication in different cochlear cell types via two distinct ATP-dependent Ca2+ waves . PURINERG SIGNAL vol. 6 , ( 2 ) 189 - 200 .
Lahne M, Gale JE ( 2008 ) . Damage-induced activation of ERK1/2 in cochlear supporting cells is a hair cell death-promoting signal that depends on extracellular ATP and calcium . J NEUROSCI vol. 28 , ( 19 ) 4918 - 4928 .
Lahne M, Lungu R, Snorton M, Yoshimatsu T, MacDonald RB . Glia regulate local retinoic acid levels to specify neuronal specialisation for high-acuity vision .
Uttley K, Papanastasiou AS, Lahne M, Brisbane JM, MacDonald RB, Bickmore WA, Bhatia S . Unique functions of two overlapping PAX6 retinal enhancers .