Publications: DR Paul Telfer

( 2025 ) . Can health inequalities in sickle cell disease be addressed through novel therapies? . HemaSphere vol. 9 , ( 7 ) Article e70175 ,

( 2025 ) . PT38 Assessing the Impact of Digital Ecosystem Engagement on Outcomes in Sickle Cell Disease (SCD) Patients . Value in Health vol. 28 , ( 6 ) S361 - S361 .

( 2025 ) . Durable Clinical Benefits in Severe Sickle Cell Disease with Exagamglogene Autotemcel . Transplantation and Cellular Therapy vol. 31 , ( 2 ) S20 - S21 .

( 2024 ) . A Virtual Hospital Approach in Sickle Cell Disease | Remote Biometric, Quality of Life, and Hospitalisations Monitoring . Blood vol. 144 , ( Supplement 1 ) 5072 - 5072 .

( 2024 ) . Comparison of Sickle Cell Disease Patient Experiences in Developed and Developing Countries: Insights from UK and India Patient Cohorts . Blood vol. 144 , ( Supplement 1 ) 5071 - 5071 .

( 2024 ) . Durable Clinical Benefits with Exagamglogene Autotemcel for Severe Sickle Cell Disease . Blood vol. 144 , ( Supplement 1 ) 4954 - 4954 .

( 2024 ) . Enhanced Artificial Intelligence (AI)-Driven Prediction of Vaso-Occlusive Crises in Sickle Cell Disease: Precision through Advanced Machine-Learning Frameworks and Digital Remote Monitoring . Blood vol. 144 , ( Supplement 1 ) 522 - 522 .

( 2024 ) . Over 4 Years of Safety and Efficacy with Voxelotor in Patients with Sickle Cell Disease . Journal of Sickle Cell Disease vol. 1 , ( Supplement_1 ) Article yoae002.008 ,

( 2024 ) . Tolérance et efficacité de voxelotor sur une période de plus de 4 ans chez les patients atteints de drépanocytose : résultats actualisés d’une étude d’extension en ouvert de l’essai de phase 3 HOPE . La Revue de Médecine Interne vol. 45 , A130 - A131 .

( 2024 ) . Exagamglogene Autotemcel for Severe Sickle Cell Disease . New England Journal of Medicine vol. 390 , ( 18 ) 1649 - 1662 .

( 2024 ) . The acute pain crisis in sickle cell disease: What can be done to improve outcomes? . Blood Reviews vol. 65 , Article 101194 , 101194 - 101194 .

( 2024 ) . Elimination of Vaso-Occlusive Crises after Exagamglogene Autotemcel in Patients with Severe Sickle Cell Disease . Transplantation and Cellular Therapy vol. 30 , ( 2 ) S234 - S235 .

( 2024 ) . Haematopoietic stem cell health in sickle cell disease and its implications for stem cell therapies and secondary haematological disorders . Blood Reviews vol. 63 , Article 101137 , 101137 - 101137 .

( 2023 ) . Exagamglogene Autotemcel for Severe Sickle Cell Disease . Blood vol. 142 , ( Supplement 1 ) 1052 - 1052 .

( 2023 ) . Over 4 Years of Safety and Efficacy with Voxelotor Treatment for Patients with Sickle Cell Disease: Updated Results from an Open-Label Extension of the Phase 3 HOPE Trial . Blood vol. 142 , ( Supplement 1 ) 2527 - 2527 .

( 2023 ) . Predicting Vaso-Occlusive Crises in Sickle Cell Disease through Digital, Longitudinal Tracking of Wearable Metrics and Patient-Reported Outcomes . Blood vol. 142 , ( Supplement 1 ) 1059 - 1059 .

( 2023 ) . Real-World Outcomes and Digitally Monitored Quality of Life in Voxelotor-Treated Patients with Sickle Cell Disease . Blood vol. 142 , ( Supplement 1 ) 2383 - 2383 .

( 2023 ) . Efficacy, safety, and pharmacokinetics of a new, ready-to-use, liquid hydroxyurea in children with sickle cell anemia . Blood Advances vol. 7 , ( 16 ) 4319 - 4322 .

( 2023 ) . P1428: PREDICTORS OF VOC RATE DURING LONG-TERM FOLLOW-UP OF PATIENTS WITH HBSS IN A NEWBORN COHORT STUDY . HemaSphere vol. 7 , ( S3 ) e7763412 - e7763412 .

( 2023 ) . P1441: REAL-WORLD OUTCOMES AND DIGITALLY MONITORED QUALITY OF LIFE IN CRIZANLIZUMAB-TREATED PATIENTS WITH SICKLE CELL DISEASE . HemaSphere vol. 7 , ( S3 ) e25264f3 - e25264f3 .

( 2023 ) . P1448: CHARACTERISATION OF QUALITY OF LIFE-LINKED PATIENT-REPORTED OUTCOMES THROUGH A DIGITAL AND CONTINUOUS REMOTE MONITORING ECOSYSTEM IN SICKLE CELL DISEASE . HemaSphere vol. 7 , ( S3 ) e53344bb - e53344bb .

( 2023 ) . Direct correction of haemoglobin E β-thalassaemia using base editors . Nature Communications vol. 14 , ( 1 ) Article 2238 ,

( 2023 ) . 5554869 ASSOCIATION BETWEEN HEMOGLOBIN LEVELS AND END-ORGAN DAMAGE IN SICKLE CELL DISEASE: A RETROSPECTIVE LINKED PRIMARY AND SECONDARY CARE DATABASE ANALYSIS IN ENGLAND . HemaSphere vol. 7 , ( S1 ) 9 - 9 .

( 2023 ) . 5609968 REAL-WORLD PATIENT-REPORTED OUTCOMES AND WEARABLE METRIC CORRELATIONS: REMOTE DAILY MONITORING FOR EXPLORATION OF QUALITY OF LIFE IN SICKLE CELL DISEASE . HemaSphere vol. 7 , ( S1 ) 8 - 9 .

( 2023 ) . 5610107 LIVE OUTCOMES AND BIOMETRIC MONITORING: POTENTIAL IMPLICATIONS FOR PATIENT QUALITY OF LIFE IN SICKLE CELL DISEASE . HemaSphere vol. 7 , ( S1 ) 54 - 54 .

( 2023 ) . 5613294 BASELINE PATIENT CHARACTERISTICS FROM A UK EARLY ACCESS TO MEDICINES SCHEME (EAMS) WITH VOXELOTOR, A HBS POLYMERIZATION INHIBITOR, FOR THE TREATMENT OF HEMOLYTIC ANEMIA DUE TO SICKLE CELL DISEASE . HemaSphere vol. 7 , ( S1 ) 16 - 17 .

( 2023 ) . 5613396 DIFFERENCE IN HOSPITALIZATIONS AND ANNUAL BED DAYS FOR PATIENTS WITH SICKLE CELL DISEASE BY VARYING LEVELS OF ANEMIA: A RETROSPECTIVE ANALYSIS OF LINKED PRIMARY AND SECONDARY CARE DATABASES IN ENGLAND . HemaSphere vol. 7 , ( S1 ) 32 - 33 .

( 2023 ) . Incidence rates for acute complications in HbSS East London newborn sickle cell cohort (ELNSCS) . BRITISH JOURNAL OF HAEMATOLOGY . vol. 201 , 40 - 40 .

( 2023 ) . Treatment of sickle cell disease with Voxelotor through the UK early access to medicines scheme . BRITISH JOURNAL OF HAEMATOLOGY . vol. 201 , 5 - 6 .

( 2022 ) . Association entre le taux d’hémoglobine et les atteintes d’organes cibles dans la drépanocytose : analyse rétrospective d’une base de données de soins primaires et secondaires en Angleterre . La Revue de Médecine Interne vol. 43 , A441 - A441 .

( 2022 ) . ASSOCIATION BETWEEN HEMOGLOBIN LEVELS AND END-ORGAN DAMAGE IN SICKLE CELL DISEASE: A RETROSPECTIVE LINKED PRIMARY AND SECONDARY CARE DATABASE ANALYSIS IN ENGLAND . Hematology, Transfusion and Cell Therapy vol. 44 , S10 - S11 .

( 2022 ) . P-037: EXPLORATION OF THE REAL-WORLD IMPACTS OF SLEEP UPON QUALITY OF LIFE IN PATIENTS WITH SICKLE CELL DISEASE . HemaSphere vol. 6 , 35 - 35 .

( 2022 ) . P1488: ASSOCIATION BETWEEN HEMOGLOBIN LEVELS AND END-ORGAN DAMAGE IN SICKLE CELL DISEASE: A RETROSPECTIVE LINKED PRIMARY AND SECONDARY CARE DATABASE ANALYSIS IN ENGLAND . HemaSphere vol. 6 , 1370 - 1371 .

( 2022 ) . P1493: CHRONIC COMPLICATIONS IN THE EAST LONDON SICKLE NEWBORN COHORT STUDY (ELSNCS) . HemaSphere vol. 6 , 1375 - 1376 .

( 2022 ) . Sécurité et efficacité à long terme du voxelotor chez des patients atteints de drépanocytose : résultats d’une étude d’extension en ouvert de l’essai de phase 3 HOPE . La Revue de Médecine Interne vol. 43 , A202 - A202 .

( 2022 ) . A retrospective comparative study of the effect of automated exchange transfusion <i>versus</i> other treatment modalities on vaso-occlusive crisis admission rates in patients with sickle cell disease . BRITISH JOURNAL OF HAEMATOLOGY . vol. 197 , 138 - 139 .

( 2022 ) . Challenges of acute and chronic pain management in sickle cell disease: Outcomes of an English national audit . BRITISH JOURNAL OF HAEMATOLOGY . vol. 197 , 11 - 12 .

( 2022 ) . P131: REAL-TIME VACCINATION IMPACTS IN SICKLE CELL DISEASE: A REAL-WORLD PATIENT CASE STUDY FOR INFLUENZA AND COVID-19 VACCINATION . HemaSphere vol. 6 , 32 - 33 .

( 2022 ) . S110: ACUTE AND CHRONIC PAIN MANAGEMENT IN SICKLE CELL DISEASE: OUTCOMES OF AN ENGLISH NATIONAL AUDIT . HemaSphere vol. 6 , 6 - 6 .

( 2022 ) . S118: LONG-TERM SAFETY AND EFFICACY OF VOXELOTOR FOR PATIENTS WITH SICKLE CELL DISEASE: RESULTS FROM AN OPEN-LABEL EXTENSION OF THE PHASE 3 HOPE TRIAL . HemaSphere vol. 6 , 9 - 10 .

( 2021 ) . Long-Term Safety and Efficacy of Voxelotor for Patients with Sickle Cell Disease: Results from an Open-Label Extension of the Phase 3 HOPE Trial . Blood vol. 138 , ( Supplement 1 ) 3114 - 3114 .

( 2021 ) . Severe Acute Complications of Sickle Cell Disease in Two Expert Referral Centers (UK and Italy): Natural History Studies Highlight Ongoing Unmet Need for Effective Disease Modifying or Curative Therapies . Blood vol. 138 , ( Supplement 1 ) 3093 - 3093 .

( 2021 ) . Routine management, healthcare resource use and patient and carer‐reported outcomes of patients with transfusion‐dependent β‐thalassaemia in the United Kingdom: A mixed methods observational study . eJHaem vol. 2 , ( 4 ) 738 - 749 .

( 2021 ) . A non-injected opioid analgesia protocol for acute pain crisis in adolescents and adults with sickle cell disease . British Journal of Pain vol. 16 , ( 2 ) 179 - 190 .

( 2021 ) . The parental perspective of thalassaemia in Bangladesh: lack of knowledge, regret, and barriers . Orphanet Journal of Rare Diseases vol. 16 , ( 1 ) Article 315 ,

( 2021 ) . The Parental Perspective of Thalassaemia in Bangladesh: Lack of knowledge, Regret, and Barriers .

( 2021 ) . Salvage of refractory post‐transfusion hyperhaemolysis by targeting hyperinflammation and macrophage activation with tocilizumab . Transfusion Medicine vol. 32 , ( 5 ) 437 - 440 .

( 2020 ) . The role of haematopoietic stem cell transplantation for sickle cell disease in the era of targeted disease-modifying therapies and gene editing . The Lancet Haematology vol. 7 , ( 12 ) e902 - e911 .

( 2020 ) . Higher Hemoglobin Levels Achieved with Voxelotor Are Associated with Lower Vaso-occlusive Crisis Incidence: 72-Week Analysis from the HOPE Study . Blood vol. 136 , ( Supplement 1 ) 31 - 32 .

( 2020 ) . Improvement in the Clinical Global Impression of Change with Voxelotor in Patients with Sickle Cell Disease in the Phase 3 HOPE Trial . Blood vol. 136 , ( Supplement 1 ) 5 - 6 .

( 2020 ) . Co‐morbidities and mortality associated with transfusion‐dependent beta‐thalassaemia in patients in England: a 10‐year retrospective cohort analysis . British Journal of Haematology vol. 191 , ( 5 ) 897 - 905 .

( 2020 ) . Real-time national survey of COVID-19 in hemoglobinopathy and rare inherited anemia patients . Haematologica vol. 105 , ( 11 ) 2651 - 2654 .

( 2020 ) . Effect of HBB genotype on survival in a cohort of transfusion-dependent thalassemia patients in Cyprus . Haematologica vol. 106 , ( 9 ) 2458 - 2468 .

( 2020 ) . Evaluation of the efficacy and safety of deferiprone compared with deferasirox in paediatric patients with transfusion-dependent haemoglobinopathies (DEEP-2): a multicentre, randomised, open-label, non-inferiority, phase 3 trial . The Lancet Haematology vol. 7 , ( 6 ) e469 - e478 .

( 2020 ) . Protecting vulnerable patients with inherited anaemias from unnecessary death during the COVID‐19 pandemic . British Journal of Haematology vol. 189 , ( 4 ) 635 - 639 .

( 2020 ) . Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): study protocol for a randomised controlled feasibility trial . Trials vol. 21 , ( 1 ) Article 347 ,

( 2020 ) . American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults . Blood Advances vol. 4 , ( 8 ) 1554 - 1588 .

( 2020 ) . Lack of knowledge and misperceptions about thalassaemia among college students in Bangladesh: a cross-sectional baseline study . Orphanet Journal of Rare Diseases vol. 15 , ( 1 ) Article 54 ,

( 2020 ) . Hydroxyurea therapy does not impact TCD velocity in the East London sickle cell newborn cohort study . BRITISH JOURNAL OF HAEMATOLOGY . vol. 189 , 146 - 147 .

( 2020 ) . Rh antibodies in patients with sickle cell disease - an on-going challenge . BRITISH JOURNAL OF HAEMATOLOGY . vol. 189 , 166 - 166 .

( 2019 ) . Not being heard: barriers to high quality unplanned hospital care during young people’s transition to adult services – evidence from ‘this sickle cell life’ research . BMC Health Services Research vol. 19 , ( 1 ) Article 876 ,

( 2019 ) . Incidence of Vaso-Occlusive Crisis Does Not Increase with Achieving Higher Hemoglobin Levels on Voxelotor Treatment or after Discontinuation: Analyses of the HOPE Study . Blood vol. 134 , ( Supplement_1 ) 2313 - 2313 .

( 2019 ) . Routine Management, Healthcare Resource Use and Patient/Caregiver-Reported Outcomes of Patients with Transfusion-Dependent β-Thalassaemia in the United Kingdom: A Mixed Methods Observational Study . Blood vol. 134 , ( Supplement_1 ) 3550 - 3550 .

( 2019 ) . PRO146 HEALTH-RELATED QUALITY OF LIFE AND PRODUCTIVITY/ACTIVITY IMPAIRMENT IN PATIENTS WITH TRANSFUSION DEPENDENT B-THALASSAEMIA IN THE UK NHS: DATA FROM A UK MULTICENTRE OBSERVATIONAL STUDY . Value in Health vol. 22 , S868 - S869 .

( 2019 ) . Evaluation of a Non-Parenteral Opioid Analgesia Protocol for Acute Sickle Cell Pain Episodes in Children . Journal of Clinical Medicine vol. 8 , ( 10 ) 1728 - 1728 .

( 2019 ) . The Role of Family Functioning in the Development of Executive Functions in Preschool Children with Sickle Cell Anemia . Developmental Neuropsychology vol. 44 , ( 6 ) 452 - 467 .

( 2019 ) . A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease . New England Journal of Medicine vol. 381 , ( 6 ) 509 - 519 .

( 2019 ) . Management of sickle cell disease: management of acute episodes in the community and in hospital . Paediatrics and Child Health vol. 29 , ( 8 ) 345 - 351 .

( 2019 ) . Management of sickle cell disease: outpatient and community aspects . Paediatrics and Child Health vol. 29 , ( 8 ) 352 - 358 .

( 2019 ) . PF785 CHANGING CAUSES OF MORTALITY IN TDT DURING THE ERA OF ORAL CHELATION THERAPY FROM 2000 TO 2018 . HemaSphere vol. 3 , ( S1 ) 346 - 347 .

( 2019 ) . S144 A MULTICENTRE, RANDOMIZED, NON‐INFERIORITY TRIAL COMPARING THE EFFICACY OF DEFERIPRONE VERSUS DEFERASIROX IN PEDIATRIC PATIENTS AFFECTED BY TRANSFUSION‐DEPENDENT HEMOGLOBINOPATHIES (DEEP‐2 TRIAL) . HemaSphere vol. 3 , ( S1 ) 23 - 24 .

( 2019 ) . S147 RESULTS FROM THE RANDOMIZED PLACEBO‐CONTROLLED PHASE 3 HOPE TRIAL OF VOXELOTOR IN ADULTS AND ADOLESCENTS WITH SICKLE CELL DISEASE . HemaSphere vol. 3 , ( S1 ) 25 - 26 .

( 2019 ) . Development and validation of the Satisfaction with Treatment for Pain Questionnaire (STPQ) among patients with sickle cell disease . British Journal of Haematology . vol. 187 , 105 - 116 .

( 2019 ) . Psychometric analysis of the adult sickle cell quality of life measurement information system (ACSQ-Me) in a UK population . Health and Quality of Life Outcomes vol. 17 , ( 1 ) Article 74 ,

( 2019 ) . A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease . Blood vol. 133 , ( 17 ) 1865 - 1875 .

( 2019 ) . FRI-437-Diagnosis of sickle cell liver disease may be aided by non-invasive tests . Journal of Hepatology . vol. 70 , e586 - e587 .

( 2019 ) . Extreme cardiac iron loading in transfusion-dependent thalassaemia major: cardiac T2* and T1 mapping guiding treatment . European Heart Journal vol. 40 , ( 43 ) 3578 - 3578 .

( 2019 ) . A Phase 1 study to determine maximum tolerated dose of sublingual fentanyl in combination with oral oxycodone for hospital management of an acute painful crisis in adolescents and adults with sickle cell disease . BRITISH JOURNAL OF HAEMATOLOGY . vol. 185 , 113 - 114 .

( 2019 ) . An observational study to evaluate the routine management, healthcare resource use and outcomes for patients with transfusion-dependent β-thalassaemia treated in the United Kingdom: an interim analysis . BRITISH JOURNAL OF HAEMATOLOGY . vol. 185 , 114 - 115 .

( 2019 ) . Causes, management and outcomes of extreme paediatric thrombocytosis . BRITISH JOURNAL OF HAEMATOLOGY . vol. 185 , 108 - 108 .

( 2019 ) . HEALTH-RELATED QUALITY OF LIFE AND PRODUCTIVITY/ACTIVITY IMPAIRMENT IN PATIENTS WITH TRANSFUSION DEPENDENT B-THALASSAEMIA IN THE UK NHS: DATA FROM A UK MULTICENTRE OBSERVATIONAL STUDY . VALUE IN HEALTH . vol. 22 , S868 - S869 .

( 2019 ) . Patients lost to follow-up in the East London Newborn Sickle Cell Cohort Study . BRITISH JOURNAL OF HAEMATOLOGY . vol. 185 , 123 - 124 .

( 2019 ) . Peer to peer mentoring for patients with Sickle Cell Disease - interim analysis of results from a pilot programme in East London . BRITISH JOURNAL OF HAEMATOLOGY . vol. 185 , 116 - 116 .

( 2018 ) . Temperament in preschool children with sickle cell anaemia . Archives of Disease in Childhood vol. 105 , ( 9 ) 900 - 902 .

( 2018 ) . Hydroxyurea Therapy Does Not Impact Current Survival Estimates in the East London Sickle Cell Newborn Cohort Study . Blood vol. 132 , ( Supplement 1 ) 3655 - 3655 .

( 2018 ) . Results from Part A of the Hemoglobin Oxygen Affinity Modulation to Inhibit HbS Polymerization (HOPE) Trial (GBT440-031), a Placebo-Controlled Randomized Study Evaluating Voxelotor (GBT440) in Adults and Adolescents with Sickle Cell Disease . Blood . vol. 132 , 505 - 505 .

( 2018 ) . Developing a risk-based composite neurologic outcome for a trial of hydroxyurea in young children with sickle cell disease . Clinical Trials vol. 16 , ( 1 ) 20 - 31 .

( 2018 ) . Newborn screening for sickle cell disease in Europe: recommendations from a Pan‐European Consensus Conference . British Journal of Haematology vol. 183 , ( 4 ) 648 - 660 .

( 2018 ) . Chronic Hepatitis C Virus Infection in Haemophilic Patients: Clinical Significance of Viral Genotype . Thrombosis and Haemostasis vol. 74 , ( 05 ) 1259 - 1264 .

( 2018 ) . Executive performance on the preschool executive task assessment in children with sickle cell anemia and matched controls . Child Neuropsychology vol. 25 , ( 2 ) 278 - 285 .

( 2018 ) . Assessment of Executive Functions in Preschool Children With Sickle Cell Anemia . Journal of the International Neuropsychological Society vol. 24 , ( 9 ) 949 - 954 .

( 2018 ) . Impact of voxelotor (GBT440) on unconjugated bilirubin and jaundice in sickle cell disease . Hematology Reports vol. 10 , ( 2 )

( 2018 ) . A Case Report of Dehydrated Hereditary Stomatocytosis and Spherocytosis . BRITISH JOURNAL OF HAEMATOLOGY . vol. 181 , 125 - 125 .

( 2018 ) . Cross-over study comparing manual exchange transfusion versus automated erythrocytapheresis. Experience of a single centre . BRITISH JOURNAL OF HAEMATOLOGY . vol. 181 , 122 - 122 .

( 2018 ) . Residential proximity to major roads and cognitive function in asymptomatic children with Sickle Cell Anaemia: a longitudinal study . BRITISH JOURNAL OF HAEMATOLOGY . vol. 181 , 117 - 117 .

( 2017 ) . Optimizing the care model for an uncomplicated acute pain episode in sickle cell disease . Hematology vol. 2017 , ( 1 ) 525 - 533 .

( 2017 ) . Are the risks of treatment to cure a child with severe sickle cell disease too high? . BMJj5250 - j5250 .

( 2017 ) . Altered Neurophysiological Processing of Auditory Attention in Preschool Children With Sickle Cell Disease . Journal of Pediatric Psychology vol. 43 , ( 8 ) 856 - 869 .

( 2016 ) . Long-Term Dosing in Sickle Cell Disease Subjects with GBT440, a Novel HbS Polymerization Inhibitor . Blood . vol. 128 , 2488 - 2488 .

( 2016 ) . Associations between environmental factors and hospital admissions for sickle cell disease . Haematologica vol. 102 , ( 4 ) 666 - 675 .

( 2016 ) . Parent reported sleep problems in preschool children with sickle cell anemia and controls in East London . Pediatric Blood &amp; Cancer vol. 64 , ( 6 ) Article e26337 ,

( 2016 ) . Transcranial Doppler Screening in a Regional Care Network for Sickle Cell Disease in the United Kingdom . Journal of Pediatric Hematology/Oncology vol. 38 , ( 7 ) 517 - 524 .

( 2016 ) . Presentations of sickle cell disease patients to hospital in Ghana: key findings from a preliminary study at Volta Regional Hospital . British Journal of Haematology vol. 178 , ( 3 ) 489 - 491 .

( 2016 ) . ASSOCIATION BETWEEN ENVIRONMENTAL FACTORS AND HOSPITAL ADMISSIONS FOR SICKLE CELL DISEASE: A RETROSPECTIVE TIME SERIES ANALYSIS . HAEMATOLOGICA . vol. 101 , 127 - 128 .

( 2016 ) . Annual review of transfusion targets in regularly transfused paediatric and adult sickle cell patients. Experiences from Bart's Health NHS Trust . BRITISH JOURNAL OF HAEMATOLOGY . vol. 173 , 153 - 154 .

( 2016 ) . GBT440, A NOVEL HBS POLYMERIZATION INHIBITOR, INCREASES HB OXYGEN AFFINITY AND RESULTS IN A RAPID IMPROVEMENT IN HEMOLYSIS AND ANEMIA . HAEMATOLOGICA . vol. 101 , 125 - 125 .

( 2016 ) . Review of an internal quality assurance programme for transcranial doppler (TCD) screening in children with sickle cell disease. Experiences from Bart's Health NHS Trust . BRITISH JOURNAL OF HAEMATOLOGY . vol. 173 , 143 - 143 .

( 2015 ) . GBT440, a Potent Anti-Sickling Hemoglobin Modifier Reduces Hemolysis, Improves Anemia and Nearly Eliminates Sickle Cells in Peripheral Blood of Patients with Sickle Cell Disease . Blood . vol. 126 , 542 - 542 .

( 2015 ) . Haploidentical BMT with a Post-Infusion of Stem Cells Cyclophosphamide Approach Is Feasible and Leads to a High Rate of Donor Engraftment in Haemoglobinopathies Allowing Universal Application of Transplantation . Blood . vol. 126 , 4317 - 4317 .

( 2015 ) . Transcranial doppler ultrasonography in primary stroke prevention in children with sickle cell disease: our initial experience: Abstract G125 Table 1 TCD screening results classified according to Adam's criteria . Archives of Disease in Childhood vol. 95 , ( Suppl 1 ) A63.3 - A64 .

( 2015 ) . Management of sickle cell disease: management of acute episodes in the community and in hospital . Paediatrics and Child Health vol. 25 , ( 8 ) 368 - 374 .

( 2015 ) . Management of sickle cell disease: out-patient and community aspects . Paediatrics and Child Health vol. 25 , ( 8 ) 375 - 380 .

( 2015 ) . White Matter Damage Relates to Oxygen Saturation in Children With Sickle Cell Anemia Without Silent Cerebral Infarcts . Stroke vol. 46 , ( 7 ) 1793 - 1799 .

( 2015 ) . Extracorporeal membrane oxygenation for the treatment of adult sickle cell acute chest syndrome . Perfusion vol. 31 , ( 3 ) 262 - 265 .

( 2015 ) . Optimal Manual Exchange Transfusion Protocol for Sickle Cell Disease: A Retrospective Comparison of Two Comprehensive Care Centers in the United Kingdom and Canada . Hemoglobin vol. 39 , ( 5 ) 310 - 315 .

( 2015 ) . Combination‐therapy with concurrent deferoxamine and deferiprone is effective in treating resistant cardiac iron‐loading in aceruloplasminaemia . British Journal of Haematology vol. 171 , ( 3 ) 430 - 432 .

( 2015 ) . 13‐valent pneumococcal conjugate vaccine (PCV13) is immunogenic and safe in children 6‐17 years of age with sickle cell disease previously vaccinated with 23‐valent pneumococcal polysaccharide vaccine (PPSV23): Results of a phase 3 study . Pediatric Blood &amp; Cancer vol. 62 , ( 8 ) 1427 - 1436 .

( 2015 ) . A comparison of chronic manual and automated red blood cell exchange transfusion in sickle cell disease patients . British Journal of Haematology vol. 170 , ( 3 ) 425 - 428 .

( 2015 ) . Effects of the 2013 MHRA update on codeine use: a retrospective study of admissions to hospital with an acute vaso-occlusive pain crisis in children with sickle cell disease . BRITISH JOURNAL OF HAEMATOLOGY . vol. 169 , 99 - 99 .

( 2015 ) . Parental Haploidentical HSCT with a Post-Infusion of Stem Cells Cyclophosphamide Approach is Feasible and Leads to a High Rate of Donor Engraftment in Haemoglobinopathies Allowing Universal Application of Transplantation . BONE MARROW TRANSPLANTATION . vol. 50 , S45 - S45 .

( 2015 ) . Sickle Cell Disease in Clinical Practice . Springer London

( 2015 ) . Transcranial Doppler screening and residual stroke rate in UK children with sickle cell disease: data from the East London and Essex clinical haemoglobinopathy network . BRITISH JOURNAL OF HAEMATOLOGY . vol. 169 , 23 - 23 .

( 2015 ) . Use of analgesia in sickle cell crisis at Volta Regional Hospital, Ho, Ghana . BRITISH JOURNAL OF HAEMATOLOGY . vol. 169 , 101 - 101 .

( 2014 ) . A Multicentre Study of Environmental Factors on the Severity of Sickle Cell Disease . Blood . vol. 124 , 4841 - 4841 .

( 2014 ) . Disease-Related Factors and Family Functioning As Predictors of Executive Functioning in Preschool Children with Sickle Cell Anaemia: A Preliminary Analysis . Blood vol. 124 , ( 21 ) 4941 - 4941 .

( 2014 ) . Deferiprone versus Deferoxamine in Sickle Cell Disease: Results from a 5-year long-term Italian multi-center randomized clinical trial . Blood Cells, Molecules, and Diseases vol. 53 , ( 4 ) 265 - 271 .

( 2014 ) . Deferasirox for iron chelation in multitransfused children with sickle cell disease; long‐term experience in the East London clinical haemoglobinopathy network . European Journal of Haematology vol. 94 , ( 4 ) 336 - 342 .

( 2014 ) . Controlled Trial of Transfusions for Silent Cerebral Infarcts in Sickle Cell Anemia . New England Journal of Medicine vol. 371 , ( 8 ) 699 - 710 .

( 2014 ) . Management of the acute painful crisis in sickle cell disease‐ a re‐evaluation of the use of opioids in adult patients . British Journal of Haematology vol. 166 , ( 2 ) 157 - 164 .

( 2013 ) . Inadequate Long-Term Control Of Transfusion Iron Overload In Children With Sickle Cell Disease Chelated With Deferasirox . Blood vol. 122 , ( 21 ) 998 - 998 .

( 2013 ) . Serial echocardiographic left ventricular ejection fraction measurements: A tool for detecting thalassemia major patients at risk of cardiac death . Blood Cells, Molecules, and Diseases vol. 50 , ( 4 ) 241 - 246 .

( 2012 ) . A Comparison of Chronic Manual and Automated Red Blood Cell Exchange Transfusion in Sickle Cell Disease Patients From Two Comprehensive Care Centres in the United Kingdom . Blood vol. 120 , ( 21 ) 3430 - 3430 .

( 2012 ) . Precursors of Executive Function in Infants With Sickle Cell Anemia . Journal of Child Neurology vol. 28 , ( 10 ) 1197 - 1202 .

Dundas I, Telfer P, Rae J, Toweh G, Onyiah N, Kaya B, Newell K, Pao C et al. ( 2012 ) . A Cohort Study Of Sleep Disordered Breathing In Pre-School Children With Sickle Cell Disease . D107. PEDIATRIC SLEEP DISORDERS . Conference: American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, CaliforniaA6659 - A6659 .

( 2012 ) . Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, sex, and relative high systolic blood pressure . Blood vol. 119 , ( 16 ) 3684 - 3690 .

( 2012 ) . Prevalence of transcranial Doppler abnormalities in Nigerian children with sickle cell disease . American Journal of Hematology vol. 87 , ( 5 ) 544 - 547 .

Telfer P, Dundas I, Rae J, Toweh G, Kaya B, Newell K, Pao C, Grigg J et al. ( 2012 ) . A cohort study of sleep disordered breathing in preschool children with sickle cell disease . BRITISH JOURNAL OF HAEMATOLOGY . vol. 157 , 70 - 71 .

( 2012 ) . Acute pain management protocols in adult sickle cell patients - audit of observation frequency following administration of opiate analgesia . BRITISH JOURNAL OF HAEMATOLOGY . vol. 157 , 74 - 75 .

( 2012 ) . Alloantibody formation in regularly transfused young patients (aged ≤ 21 years) with sickle cell disease - a single centre review . BRITISH JOURNAL OF HAEMATOLOGY . vol. 157 , 82 - 82 .

( 2012 ) . Use of individualised acute pain management protocols in adult sickle cell patients - a single centre experience . BRITISH JOURNAL OF HAEMATOLOGY . vol. 157 , 75 - 75 .

( 2011 ) . Cervical carotid artery disease in sickle cell anemia: clinical and radiological features . Blood vol. 118 , ( 23 ) 6192 - 6199 .

( 2011 ) . Hydroxycarbamide use in young children with sickle-cell anaemia . The Lancet vol. 378 , ( 9805 ) 1777 - 1777 .

( 2011 ) . Management of sickle cell disease: acute episodes in the community and in hospital . Paediatrics and Child Health vol. 21 , ( 8 ) 363 - 368 .

( 2011 ) . Management of sickle cell disease: out-patient and community aspects . Paediatrics and Child Health vol. 21 , ( 8 ) 357 - 362 .

( 2011 ) . An audit of a transfusion algorithm for use in paediatric thalassaemia patients . BRITISH JOURNAL OF HAEMATOLOGY . vol. 153 , 66 - 67 .

( 2011 ) . Low risk of stroke in children with sickle cell disease (SCD) screened with transcranial Doppler (TCD) ultrasound . BRITISH JOURNAL OF HAEMATOLOGY . vol. 153 , 26 - 27 .

( 2011 ) . Percutaneous endoscopic gastrostomy feeds in children with sickle cell disease and growth failure; a novel approach with high patient and carer satisfaction . BRITISH JOURNAL OF HAEMATOLOGY . vol. 153 , 65 - 65 .

( 2010 ) . Management of chronic viral hepatitis in patients with thalassemia: recommendations from an international panel . Blood vol. 116 , ( 16 ) 2875 - 2883 .

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