Publications: PROF Karin Hing

Mafina M-K, Wilson RM, Rees GJ, Gierth P, Sullivan AC, Hing KA ( 2023 ) . SSNMR confirms silicate ion substitution in the apatitic structure of 0.8wt% Si hydroxyapatite . Academia Materials Science vol. 1 , ( 1 )

Mafina M-K, Wilson R, Rees G, Gierth P, Sullivan A, Hing K ( 2023 ) . SSNMR confirms silicate ion substitution in the apatitic\nstructure of 0.8wt% Si hydroxyapatite . Academia materials science

Zhou B, Jiang Y, Guo Q, Das A, Sobrido ABJ, Hing KA, Zayats AV, Krause S ( 2022 ) . Photoelectrochemical Detection of Calcium Ions Based on Hematite Nanorod Sensors . ACS Applied Nano Materials vol. 5 , ( 11 ) 17087 - 17094 .

Zhou B, Jiang Y, Guo Q, Das A, Sobrido A, Hing K, Zayats A, Krause S ( 2022 ) . Photoelectrochemical detection of calcium ions based on hematite nanorod sensor substrates .

Kohnken-Sawall J, Rawlinson SCF, Hing KA ( 2022 ) . OSTEOGENIC ACTIVITY OF ACTIFUSE™ IS NOT ENHANCED BY PRE-ADSORBED BMP2 . TISSUE ENGINEERING PART A . vol. 28 , S42 - S42 .

Zhou B, Das A, Zhong M, Guo Q, Zhang D-W, Hing KA, Sobrido AJ, Titirici M-M et al. ( 2021 ) . Photoelectrochemical imaging system with high spatiotemporal resolution for visualizing dynamic cellular responses . Biosensors and Bioelectronics vol. 180 , Article 113121 , 113121 - 113121 .

Hexter AT, Hing KA, Haddad FS, Blunn G ( 2020 ) . Decellularized porcine xenograft for anterior cruciate ligament reconstruction . Bone & Joint Research vol. 9 , ( 6 ) 293 - 301 .

Wu F, Zhou B, Wang J, Zhong M, Das A, Watkinson M, Hing K, Zhang D-W et al. ( 2019 ) . Photoelectrochemical Imaging System for the Mapping of Cell Surface Charges . Analytical Chemistry vol. 91 , ( 9 ) 5896 - 5903 .

Mafina M-K, Sullivan AC, Hing KA ( 2017 ) . Use of a fluorescent probe to monitor the enhanced affinity of rh-BMP-2 to silicated-calcium phosphate synthetic bone graft substitutes under competitive conditions . Materials Science and Engineering: C vol. 80 , 207 - 212 .

Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG ( 2017 ) . The effect of the incorporation of fluoride into strontium containing bioactive glasses . Journal of Non-Crystalline Solids vol. 457 , 25 - 30 .

Campion C, Hing KA ( 2016 ) . Porous Bone Graft Substitutes . Wiley

Coathup MJ, Blunn GW, Campion C, Ho C, Hing KA ( 2016 ) . The effect of increased microporosity on bone formation within silicate‐substituted scaffolds in an ovine posterolateral spinal fusion model . Journal of Biomedical Materials Research Part B: Applied Biomaterials vol. 105 , ( 4 ) 805 - 814 .

Sriranganathan D, Kanwal N, Hing KA, Hill RG ( 2015 ) . Strontium substituted bioactive glasses for tissue engineered scaffolds: the importance of octacalcium phosphate . Journal of Materials Science: Materials in Medicine vol. 27 , ( 2 ) Article 39 ,

Hutchens SA, Campion C, Assad M, Chagnon M, Hing KA ( 2015 ) . Efficacy of silicate-substituted calcium phosphate with enhanced strut porosity as a standalone bone graft substitute and autograft extender in an ovine distal femoral critical defect model . Journal of Materials Science: Materials in Medicine vol. 27 , ( 1 ) Article 20 ,

Shah FA, Brauer DS, Hill RG, Hing KA ( 2015 ) . Apatite formation of bioactive glasses is enhanced by low additions of fluoride but delayed in the presence of serum proteins . Materials Letters vol. 153 , 143 - 147 .

Shah FA, Brauer DS, Desai N, Hill RG, Hing KA ( 2014 ) . Fluoride-containing bioactive glasses and Bioglass® 45S5 form apatite in low pH cell culture medium . Materials Letters vol. 119 , 96 - 99 .

Huang J, Hing KA, Best SM, Lee DA, Silvio LD, Bonfield W ( 1999 ) . A COMPARATIVE STUDY OF VARIOUS ASSAYS FOR <i>IN VITRO</i> BIOCOMPATIBILITY ASSESSMENT OF EXPERIMENTAL ZIRCONIA . Bioceramics . Conference: Proceedings of the 12th International Symposium on Ceramics in Medicine199 - 202 .

Hing KA, Merry JC, Gibson IR, Di-Silvio L, Best SM, Bonfield W ( 1999 ) . EFFECT OF CARBONATE CONTENT ON THE RESPONSE OF HUMAN OSTEOBLAST-LIKE CELLS TO CARBONATE SUBSTITUTED HYDROXYAPATITE . Bioceramics . Conference: Proceedings of the 12th International Symposium on Ceramics in Medicine195 - 198 .

Parsons NS, Hing KA, Buckland T, Best SM, Bonfield W ( 1999 ) . PHYSICAL PROPERTIES OF A NOVEL GLASS-CERAMIC-REINFORCED HYRDROXYAPATITE COMPOSITE . Bioceramics . Conference: Proceedings of the 12th International Symposium on Ceramics in Medicine413 - 416 .

Ghani Y, Coathup MJ, Hing KA, Blunn GW ( 2013 ) . Antibacterial effect of incorporating silver ions in electrochemically deposited hydroxyapatite coating: An experimental study . JRSM Short Reports vol. 4 , ( 9 ) Article 2042533313481212 ,

Castagna V, Olivares-Navarrete R, Schwartz Z, Boyan BD, Hing KA ( 2013 ) . HMSC proliferation and differentiation are dependent on chemistry and surface roughness of calcium phosphate bone substitutes . European Cells and Materials vol. 26 , ( SUPPL. 3 )

Shah FA, Brauer DS, Wilson RM, Hill RG, Hing KA ( 2013 ) . Influence of cell culture medium composition on <i>in vitro</i> dissolution behavior of a fluoride‐containing bioactive glass . Journal of Biomedical Materials Research Part A vol. 102 , ( 3 ) 647 - 654 .

Mafina M-K, Hing KA, Sullivan AC ( 2013 ) . Development of Novel Fluorescent Probes for the Analysis of Protein Interactions under Physiological Conditions with Medical Devices . Langmuir vol. 29 , ( 5 ) 1420 - 1426 .

Hing KA ( 2013 ) . 8 Biomimetic bone regeneration . Biomimetic Biomaterials , Elsevier

Hing KA ( 2013 ) . Biomimetic bone regeneration . 207 - 237 .

Ruys A, Tampieri A, Sprio S, Ehrlich H, Rabiei R, Dastjerdi AK, Mirkhalaf M, Barthelat F et al. ( 2013 ) . Contributor contact details . Biomimetic Biomaterials , Elsevier

Campion CR, Ball SL, Clarke DL, Hing KA ( 2012 ) . Microstructure and chemistry affects apatite nucleation on calcium phosphate bone graft substitutes . Journal of Materials Science: Materials in Medicine vol. 24 , ( 3 ) 597 - 610 .

Chan O, Coathup MJ, Nesbitt A, Ho C-Y, Hing KA, Buckland T, Campion C, Blunn GW ( 2012 ) . The effects of microporosity on osteoinduction of calcium phosphate bone graft substitute biomaterials . Acta Biomaterialia vol. 8 , ( 7 ) 2788 - 2794 .

Coathup MJ, Hing KA, Samizadeh S, Chan O, Fang YS, Campion C, Buckland T, Blunn GW ( 2012 ) . Effect of increased strut porosity of calcium phosphate bone graft substitute biomaterials on osteoinduction . Journal of Biomedical Materials Research Part A vol. 100A , ( 6 ) 1550 - 1555 .

Ozad U, Parish A, Hing KA ( 2012 ) . Bioactivity And Bone Formation In Silicon-Substituted Hydroxyapatite . SAÜ Fen Bilimleri Enstitüsü Dergisi vol. 16 , ( 3 ) 170 - 177 .

Campion R, Ball S, Clarke D, Hing K ( 2012 ) . Microstructure and chemistry affects the <i>in vitro</i> bioactivity of calcium phosphate bone graft substitutes . JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE . vol. 6 , 232 - 232 .

Campion C, Ball S, Clarke D, Hing K ( 2012 ) . Microstructure and chemistry affects the in vitro bioactivity of calcium phosphate bone graft substitutes . JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE . vol. 6 , 424 - 425 .

Coathup MJ, Samizadeh S, Fang YS, Buckland T, Hing KA, Blunn GW ( 2011 ) . The Osteoinductivity of Silicate-Substituted Calcium Phosphate . Journal of Bone and Joint Surgery vol. 93 , ( 23 ) 2219 - 2226 .

Castagna V, Sullivan A, Hing K ( 2011 ) . Fibronectin adsorption to stoichiometric and silicate substituted hydroxyapatite sensitive to FN concentration and presence of serum proteins . 24th European Conference on Biomaterials Annual Conference of the European Society for Biomaterials

Parish A, Davis G, Hing K ( 2011 ) . The quantitative and qualitative analysis bone ingrowth network quality of hydroxyapatite implants over time to investigate the process of internal bone growth via novel automated 3D image processing . 24th European Conference on Biomaterials Annual Conference of the European Society for Biomaterials

Guth K, Campion C, Buckland T, Hing KA ( 2011 ) . Effects of serum protein on ionic exchange between culture medium and microporous hydroxyapatite and silicate-substituted hydroxyapatite . J MATER SCI-MATER M vol. 22 , ( 10 ) 2155 - 2164 .

Ghani Y, Coathup MJ, Hing KA, Blunn GW ( 2011 ) . Development of a hydroxyapatite coating containing silver for the prevention of peri‐prosthetic infection . Journal of Orthopaedic Research vol. 30 , ( 3 ) 356 - 363 .

Campion CR, Chander C, Buckland T, Hing K ( 2011 ) . Increasing strut porosity in silicate-substituted calcium-phosphate bone graft substitutes enhances osteogenesis . J BIOMED MATER RES B vol. 97B , ( 2 ) 245 - 254 .

Parish AJB, Davis GR, Hing KA ( 2011 ) . Automated computation of 3D histomorphometry within implanted hydroxyapatite porous scaffolds . European Cells and Materials vol. 22 , ( SUPPL.2 )

Castagna V, Sullivan A, Hing KA ( 2011 ) . Behaviour of fibronectin on interaction with stoichiometric and silicate substituted hydroxyapatite bone graft substitiutes . European Cells and Materials vol. 22 , ( SUPPL.2 )

Mafina MK, Sullivan AC, Hing KA ( 2011 ) . Recording and evaluating the effect of silicon-substitution on protein adsorption/desorption to hydroxyapatite . European Cells and Materials vol. 22 , ( SUPPL.2 )

Guth K, Campion C, Buckand T, Hing KA ( 2010 ) . Surface Physiochemistry Affects Protein Adsorption to Stoichiometric and Silicate-Substituted Microporous Hydroxyapatites . ADV ENG MATER vol. 12 , ( 4 ) B113 - B121 .

Guth K, Campion C, Buckland T, Hing KA ( 2010 ) . Effect of Silicate-Substitution on Attachment and Early Development of Human Osteoblast-Like Cells Seeded on Microporous Hydroxyapatite Discs . ADV ENG MATER vol. 12 , ( 1-2 ) B26 - B36 .

Hing K ( 2010 ) . Tissue engineering . MATERIALS WORLD vol. 18 , ( 9 ) 28 - 30 .

Mafina MK, Sullivan AC, Hing KA ( 2009 ) . Monitoring the effect of silicate substitution on protein adsorption/desorption to hydroxyapatite . European Cells and Materials vol. 18 , ( SUPPL. 2 )

HING KA, Bonfield W ( 2009 ) . foamed ceramics . no. US 12/216,710 ,

Christophy C, Rashid N, Di Silvio L, Hing KA ( 2009 ) . Encouraging Nature with Ceramics: The roles of surface roughness and physio-chemistry on cell response to substituted apatites . BIOMEDICAL APPLICATIONS OF SMART MATERIALS, NANOTECHNOLOGY AND MICRO/NANO ENGINEERING . vol. 57 , 22 - 30 .

Samizadeh S, Amogbokpa J, Fang SC, Coathup MJ, Hing KA, Buckland T, Blunn GW ( 2008 ) . Osseoinduction by calcium phosphate bone substitutes is a function of chemical composition and structure . 8th World Biomaterials Congress 2008 vol. 2 ,

Hing KA ( 2008 ) . Biomaterials — where biology, physics, chemistry, engineering and medicine meet . Journal of Physics: Conference Series . vol. 105 , 012010 - 012010 .

Hing KA ( 2008 ) . Biomaterials - Where biology, physics, chemistry, engineering and medicine meet . Journal of Physics Conference Series vol. 105 , ( 1 )

Rashid N, Harding IS, Buckland T, Hing KA ( 2008 ) . Nano-scale manipulation of silicate-substituted apatite chemistry impacts surface charge, hydrophilicity, protein adsorption and cell attachment . International Journal of Nano and Biomaterials vol. 1 , ( 3 ) Article 16877 , 299 - 299 .

Hing KA, Wilson LE, Buckland T ( 2007 ) . Comparative performance of three ceramic bone graft substitutes . SPINE J vol. 7 , ( 4 ) 475 - 490 .

Mabilleau G, Xia Z, Hing KA, Buckland T, Sabokbar A ( 2007 ) . Osteoclastic responses to phase pure hydroxyapatite (HA) and silicon (SI)-substituted HA . TISSUE ENGINEERING . vol. 13 , 1388 - 1388 .

De Carlos A, Lusquiños F, Pou J, León B, Pérez-Amor M, Driessens FCM, Hing K, Best S et al. ( 2006 ) . In vitro testing of Nd:YAG laser processed calcium phosphate coatings . Journal of Materials Science: Materials in Medicine . vol. 17 , 1153 - 1160 .

Hing KA, Revell PA, Smith N, Buckland T ( 2006 ) . Effect of silicon level on rate, quality and progression of bone healing within silicate-substituted porous hydroxyapatite scaffolds . BIOMATERIALS vol. 27 , ( 29 ) 5014 - 5026 .

Guth K, Buckland T, Hing KA . Silicon Dissolution from Microporous Silicon Substituted Hydroxyapatite and its Effect on Osteoblast Behaviour . Key Engineering Materials . vol. 309-311 , 117 - 120 .

De Carlos A, Lusquinos F, Pou J, Leon B, Perez-Amor M, Driessens FCM, HING KA, Best S et al. ( 2006 ) . In vitro testing of Nd : YAG laser processed calcium phosphate coatings . Journal of Materials Science Materials in Medicine vol. 17 , ( 11 ) 1153 - 1160 .

Harding IS, Rashid N, Hing KA ( 2005 ) . Surface charge and the effect of excess calcium ions on the hydroxyapatite surface . BIOMATERIALS vol. 26 , ( 34 ) 6818 - 6826 .

Mehta JS ( 2005 ) . Hydroxyapatite promotes superior keratocyte adhesion and proliferation in comparison with current keratoprosthesis skirt materials . British Journal of Ophthalmology vol. 89 , ( 10 ) 1356 - 1362 .

Hing KA ( 2005 ) . Bioceramic Bone Graft Substitutes: Influence of Porosity and Chemistry . International Journal of Applied Ceramic Technology vol. 2 , ( 3 ) 184 - 199 .

Hing KA, Annaz B, Saeed S, Revell PA, Buckland T ( 2005 ) . Microporosity enhances bioactivity of synthetic bone graft substitutes . Journal of Materials Science: Materials in Medicine . vol. 16 , 467 - 475 .

HING KA, Annaz B, Saeed S, Revell PA, Buckland T ( 2005 ) . Microporosity enhances bioactivity of synthetic bone graft substitutes . Journal of Materials Science Materials in Medicine vol. 16 , ( 5 ) 467 - 475 .

Hing KA ( 2004 ) . Bone repair in the twenty-first century: biology, chemistry or engineering? . PHILOS T ROY SOC A vol. 362 , ( 1825 ) 2821 - 2850 .

Hing KA, Saeed S, Annaz B, Buckland T, Revell PA ( 2004 ) . Bone development is sensitive to silicon level in substituted apatites . Transactions 7th World Biomaterials Congress

Rashid N, Harding I, Hing KA ( 2004 ) . Effect of silicate substitution on the surface charge of hydroxyapatite . Transactions 7th World Biomaterials Congress

Saeed S, Hing K, Revell PA ( 2004 ) . HA activates T cells and causes inflammation in liver and spleen from rabbits following intraosseous implantation . Transactions 7th World Biomaterials Congress

Hing KA, Saeed S, Annaz B, Buckland T, Revell PA ( 2004 ) . Microporosity enhances bioactivity of synthetic bone graft substitutes . Transactions 7th World Biomaterials Congress

Annaz B, Hing KA, Kayser M, Buckland T, Di Silvio L ( 2004 ) . The role of microporosity in synthetic porous ceramics . Transactions 7th World Biomaterials Congress

Annaz B, Hing KA, Kayser M, Buckland T, Di Silvio L ( 2004 ) . An ultrastructural study of cellular response to variation in porosity in phase-pure hydroxyapatite . J MICROSC-OXFORD vol. 216 , 97 - 109 .

Annaz B, Hing KA, Kayser M, Buckland T, Di Silvio L ( 2004 ) . Porosity variation in hydroxyapatite and osteoblast morphology: a scanning electron microscopy study . J MICROSC-OXFORD vol. 215 , 100 - 110 .

Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA ( 2004 ) . Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes . J BIOMED MATER RES A vol. 68A , ( 1 ) 187 - 200 .

HING KA, Revell PA, McInness T, Damien E ( 2004 ) . Novel Bioceramic Foams For Bone Grafting . Journal of Bone & Joint Surgery - British Volume vol. 86-B Suppl I:II ,

Hing KA, Saeed S, Annaz B, Buckland T, Revell PA . Microporosity Affects Bioactivity of Macroporous Hydroxyapatite Bone Graft Substitutes . Key Engineering Materials . vol. 254-256 , 273 - 276 .

Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA ( 2003 ) . Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes . Journal of Biomedical Materials Research Part A vol. 68A , ( 1 ) 187 - 200 .

Damien E, Hing K, Saeed S, Revell PA ( 2003 ) . A preliminary study on the enhancement of the osteointegration of a novel synthetic hydroxyapatite scaffold in vivo . JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A vol. 66A , ( 2 ) 241 - 246 .

Lusquinos F, De Carlos A, Pou J, Arias JL, Boutinguiza M, Leon B, Perez-Amor M, Driessens FCM et al. ( 2003 ) . Calcium phosphate coatings obtained by Nd : YAG laser cladding: Physicochemical and biologic properties . J BIOMED MATER RES A vol. 64A , ( 4 ) 630 - 637 .

Patel N, Best SM, Bonfield W, Gibson IR, Hing KA, Damien E, Revell PA ( 2002 ) . A comparative study on the in vivo behavior of hydroxyapatite and silicon substituted hydroxyapatite granules . J MATER SCI-MATER M vol. 13 , ( 12 ) 1199 - 1206 .

Pedroviejo JJ, Reusmaazran Yusof M, Besar I, Mustafa R, Hing KA . Fabrication of Porous Hydroxyapatite by Foam Technique . Key Engineering Materials . vol. 206-213 , 1543 - 1546 .

Ke S, Gibson IR, Hing KA . Characterisation of Mono- and Biphasic Calcium Phosphates Granules . Key Engineering Materials . vol. 218-220 , 625 - 628 .

Gibson IR, Hing KA, Revell PA, Santos JD, Best S, Bonfield W . Enhanced In Vivo Response to Silicate-Substituted Hydroxyapatite . Key Engineering Materials . vol. 218-220 , 203 - 206 .

Patel N, Gibson IR, Hing KA, Best S, Damien E, Revell PA, Bonfield W . The In Vivo Response of Phase Pure Hydroxyapatite and Carbonate Substituted Hydroxyapaite Granules of Varying Size Ranges . Key Engineering Materials . vol. 218-220 , 383 - 386 .

Damien E, MacInnes T, Hing K, Revell PA ( 2001 ) . Insulin like growth factor (IGF-I) increases the bioactivity of porous hydroxyapatite (PHA) <i>in vivo</i> in rabbits . JOURNAL OF PATHOLOGY vol. 193 , 6A - 6A .

Hing KA, Gibson IR, Revell PA, Best S, Bonfield W . Influence of Phase Purity on the in Vivo Response to Hydroxyapatite . Key Engineering Materials . vol. 192-195 , 373 - 376 .

Patel N, Best S, Gibson IR, Ke S, Hing KA, Bonfield W . Preparation and Characterisation of Hydroxyapatite and Carbonate Substituted Hydroxyapatite Granules . Key Engineering Materials . vol. 192-195 , 7 - 10 .

Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA ( 1999 ) . Quantification of bone ingrowth within bone-derived porous hydroxyapatite implants of varying density . J MATER SCI-MATER M vol. 10 , ( 10-11 ) 663 - 670 .

Hing KA, Best SM, Bonfield W ( 1999 ) . Characterization of porous hydroxyapatite . J MATER SCI-MATER M vol. 10 , ( 3 ) 135 - 145 .

Di Silvio L, Hing K, Bonfield W ( 1999 ) . Macroporous hydroxyapatites: Potential drug delivery systems . Proceedings of the Controlled Release Society ( 26 ) 1152 - 1153 .

Di Silvio L, Hing K, Bonfield W ( 1998 ) . A degradable drug delivery system for orthopaedic application . NEW BIOMEDICAL MATERIALS . vol. 16 , 125 - 129 .

Hing KA, Best SM, Tanner KE, Revell PA, Bonfield W ( 1998 ) . Histomorphological and biomechanical characterization of calcium phosphates in the osseous environment . P I MECH ENG H vol. 212 , ( H6 ) 437 - 451 .

Hing K, Knight M ( 1998 ) . Prize-winning peeks at the microscopic world .

Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA ( 1997 ) . Biomechanical assessment of bone ingrowth in porous hydroxyapatite . JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE vol. 8 , ( 12 ) 731 - 736 .

Lopes MA, Knowles JC, Hing KA, Santos JD, Monteiro FJ, Olsen I ( 1997 ) . Biological evaluation of glass reinforced hydroxyapatite by flow cytometry . 575 - 578 .

Hing KA, Di-Silvio L, Gibson IR, Ohtsuki C, Jha LJ, Best SM, Bonfield W ( 1997 ) . Effect of fluoride substitution of the biocompatibility of hydroxyapatite . 19 - 22 .

Revell PA, Hing KA, Tanner KE, Best SM, Bonfield W ( 1997 ) . Osseointegration of porous hydroxyapatite . BONE GRAFT SUBSTITUTES AND GROWTH FACTORS . 28 - 30 .

Hing KA, Best SM, Revell PA, Tanner KE, Bonfield W ( 1996 ) . Histomorphometric and biomechanical assessment of bone ingrowth in porous hydroxyapatite . Transactions of the Annual Meeting of the Society for Biomaterials in Conjunction with the International Biomaterials Symposium vol. 2 ,

HING KA ( 1996 ) . Assessment of porous hydroxyapatite for bone replacement . Presented at: Queen Mary University of London ,

Krause S, Zhou B, Jiang Y, Guo Q, Das A, Sobrido AJ, Hing KA, Zayats AV . Hematite Nanorods as a Platform for Photoelectrochemical Imaging and Sensing .