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Research

Publications: DR Jesmond Dalli

Chen J, Purvis GSD, Collotta D, AI Zoubi S, Sugimoto MA, Cacace A, Martin L, Colas RA et al. ( 2025 ) . Correction: RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance . Frontiers in Immunology vol. 16 , Article 1659224 ,
Gutjahr JC, Hub E, Anderson CA, Samus M, Artinger K, Gomez EA, Ratswohl C, Wickli N et al. ( 2025 ) . Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation . Science Signaling vol. 18 , ( 891 ) Article eadt2678 ,
Malactou C, Hayes M, Zhang T, Ward S, Harwood C, Dalli J, Strid J ( 2025 ) . Eosinophils and Bioactive Lipid Mediators Regulate Skin Inflammation and Cancer Growth . Journal of Investigative Dermatology
( 2025 ) . Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis . EMBO Molecular Medicine vol. 17 , ( 5 ) 1153 - 1183 .
Rispoli RM, Popolo A, De Fabrizio V, d’Emmanuele di Villa Bianca R, Autore G, Dalli J, Marzocco S ( 2025 ) . Targeting Inflammatory Imbalance in Chronic Kidney Disease: Focus on Anti-Inflammatory and Resolution Mediators . International Journal of Molecular Sciences vol. 26 , ( 7 ) 3072 - 3072 .
Ringheim-Bakka TA, Saliani A, Østbye T-KK, Mildenberger J, Dooley M, Busygina M, Pedersen ME, Solberg NT et al. ( 2025 ) . Herring roe PLs promote SPM biosynthesis in macrophages and a keratinocyte/fibroblast co-culture as model of psoriasis .
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Schneider AH, Cecconello C, Bu W, Imbert PRC et al. ( 2025 ) . Formyl-peptide receptor type 2 activation mitigates secondary organ damage in inflammatory arthritis .
Albuquerque-Souza E, Dalli J ( 2025 ) . Specialized pro-resolving lipid mediators in gut immunophysiology: from dietary precursors to inflammation resolution . Current Opinion in Clinical Nutrition & Metabolic Care vol. 28 , ( 2 ) 96 - 103 .
Fisk M, Gomez EA, Sun Y, Mickute M, McEniery C, Cockcroft JR, Bolton C, Fuld J et al. ( 2025 ) . Dysregulation of lipid mediators in patients with frequent exacerbations of COPD . ERJ Open Research vol. 11 , ( 2 ) 00950 - 2023 .
Filor V, Myslinska J, Saliani A, Dalli J, Steinbach S, Olinga P, Bäumer W, Werling D ( 2025 ) . Pre-stimulation of Precision-Cut bovine udder slices with zymosan before LPS exposure indicates indicators for trained immunity .
Dooley M, Saliani A, Dalli J ( 2024 ) . Development and Validation of Methodologies for the Identification of Specialized Pro-Resolving Lipid Mediators and Classic Eicosanoids in Biological Matrices . Journal of the American Society for Mass Spectrometry vol. 35 , ( 10 ) 2331 - 2343 .
( 2024 ) . An <i>LGR6</i> frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections . Blood vol. 144 , ( 4 ) 420 - 434 .
Leuti A, Fava M, Forte G, Pellegrini N, Oddi S, Scipioni L, Gomez EA, Dalli J et al. ( 2024 ) . The endocannabinoid anandamide activates pro‐resolving pathways in human primary macrophages by engaging both <scp>CB<sub>2</sub></scp> and <scp>GPR18</scp> receptors . The FASEB Journal vol. 38 , ( 10 ) Article e23675 ,
Rodrigues-Diez R, Ballesteros-Martinez C, Moreno-Carriles RM, Nistal F, Díaz del Campo LS, Cachofeiro V, Dalli J, García-Redondo AB et al. ( 2024 ) . Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors . Biomedicine &amp; Pharmacotherapy vol. 174 , Article 116564 , 116564 - 116564 .
Walker ME, De Matteis R, Perretti M, Dalli J ( 2024 ) . Resolvin T4 enhances macrophage cholesterol efflux to reduce vascular disease . Nature Communications vol. 15 , ( 1 ) Article 975 ,
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al. ( 2024 ) . Addendum: Resolvins suppress tumor growth and enhance cancer therapy . Journal of Experimental Medicine vol. 221 , ( 3 ) Article e2017068101232024a ,
Aguirre GA, Goulart MR, Bank BPT, Dalli J, Kocher HM ( 2024 ) . Corrigendum: Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion . Frontiers in Immunology vol. 15 , Article 1353835 ,
Koenis DS, de Matteis R, Rajeeve V, Cutillas P, Dalli J ( 2023 ) . Efferocyte‐Derived MCTRs Metabolically Prime Macrophages for Continual Efferocytosis via Rac1‐Mediated Activation of Glycolysis . Advanced Science vol. 11 , ( 7 ) Article 2304690 ,
Chen J, Oggero S, Cecconello C, Dalli J, Hayat H, Hjiej Andaloussi A, Sanni S, Jonassen TEN et al. ( 2023 ) . The Annexin-A1 mimetic RTP-026 promotes acute cardioprotection through modulation of immune cell activation . Pharmacological Research vol. 198 , Article 107005 , 107005 - 107005 .
Aguirre GA, Goulart MR, Dalli J, Kocher HM ( 2023 ) . Arachidonate 15-lipoxygenase-mediated production of Resolvin D5n-3 DPA abrogates pancreatic stellate cell-induced cancer cell invasion . Frontiers in Immunology vol. 14 , Article 1248547 ,
Dalli J, Gomez EA ( 2023 ) . Reply to: Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples . Nature Communications vol. 14 , ( 1 ) Article 7293 ,
Ervik K, Reinertsen AF, Koenis DS, Dalli J, Hansen TV ( 2023 ) . Stereoselective Synthesis, Pro-resolution, and Anti-inflammatory Actions of RvD5<sub>n-3 DPA</sub> . Journal of Natural Products vol. 86 , ( 11 ) 2546 - 2553 .
Laiglesia LM, Escoté X, Sáinz N, Felix-Soriano E, Santamaría E, Collantes M, Fernández-Galilea M, Colón-Mesa I et al. ( 2023 ) . Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice . Molecular Metabolism vol. 74 , Article 101749 , 101749 - 101749 .
Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM, Barillas-Mury C ( 2023 ) . Author Correction: A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae . Nature Communications vol. 14 , ( 1 ) Article 4305 ,
Mai NTH, Dobbs N, Phu NH, Colas RA, Thao LTP, Thuong NTT, Nghia HDT, Hanh NHH et al. ( 2023 ) . Correction: A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults . eLife vol. 12 , Article e87888 ,
Dalli J ( 2023 ) . Mistakes in the re-analysis of lipidomic data obtained from a human model of resolving inflammation lead to erroneous conclusions .
Dalli J, Kitch D, O'Brien MP, Hunt PW, Funderburg N, Moisi D, Gupta A, Brown TT et al. ( 2023 ) . Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin intervention . eBioMedicine vol. 89 , Article 104468 , 104468 - 104468 .
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al. ( 2023 ) . Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis . JCI Insight vol. 8 , ( 3 ) Article e168728 ,
Perretti M, Dalli J ( 2023 ) . Resolution Pharmacology: Focus on Pro-Resolving Annexin A1 and Lipid Mediators for Therapeutic Innovation in Inflammation . Annual Review of Pharmacology and Toxicology vol. 63 , ( 1 ) 449 - 469 .
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al. ( 2023 ) . Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans . Journal of Clinical Investigation vol. 133 , ( 2 ) Article e168068 ,
Flak MB, Koenis DS, Gonzalez-Nunez M, Chopo-Pizarro A, Dalli J ( 2023 ) . Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation . Biochemical Pharmacology vol. 207 , Article 115348 , 115348 - 115348 .
Díaz del Campo LS, García-Redondo AB, Rodríguez C, Zaragoza C, Duro-Sánchez S, Palmas F, de Benito-Bueno A, Socuéllamos PG et al. ( 2023 ) . Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension . Hypertension vol. 80 , ( 1 ) 84 - 96 .
Silva RA, Domingos R, Trujillo M, Filho A, Oliveira C, Baldini R, Dalli J, Netto L ( 2022 ) . LsfA, a 1-Cys Peroxiredoxin involved with Pseudomonas aeruginosa virulence: Structure, biochemical activity, and its influence in inflammation/resolution . Free Radical Biology and Medicine vol. 192 , 117 - 117 .
Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J, Pitzalis C ( 2022 ) . Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis . JCI Insight vol. 7 , ( 20 ) Article e165600 ,
Dalli J, Rodriguez A, Spur B, Serhan C . Structure elucidation and biological evaluations of sulfido-conjugated specialized pro-resolving mediators . Proceedings of 2022 AOCS Annual Meeting &amp; Expo . Conference: 2022 AOCS Annual Meeting & Expo
Sips M, Gerlo S, De Clercq L, Gomez EA, Colas RA, Dalli J, Vandekerckhove L ( 2022 ) . Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature . Immunity, Inflammation and Disease vol. 10 , ( 6 ) Article e629 ,
Caravaca AS, Gallina AL, Tarnawski L, Shavva VS, Colas RA, Dalli J, Malin SG, Hult H et al. ( 2022 ) . Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit . Proceedings of the National Academy of Sciences vol. 119 , ( 22 ) Article e2023285119 ,
Keogh A, Clarke J, Rabani R, Dalli J, Godson C, Curley G ( 2022 ) . Lipoxin A4 Mediates Mesenchymal Stromal Cell Therapeutic Effects in Sepsis . A101. DEFINING CELLULAR AND MOLECULAR IMMUNE MECHANISMS IN LUNG INFECTIONS, ARDS, AND SEPSIS . Conference: American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CAA2198 - A2198 .
Pistorius K, Ly L, Souza PR, Gomez EA, Koenis DS, Rodriguez AR, Foster J, Sosabowski J et al. ( 2022 ) . MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis . eBioMedicine vol. 79 , Article 103974 , 103974 - 103974 .
Dalli J, Gomez EA, Serhan CN ( 2022 ) . Evidence for the presence and diagnostic utility of SPM in human peripheral blood .
Dyall SC, Balas L, Bazan NG, Brenna JT, Chiang N, da Costa Souza F, Dalli J, Durand T et al. ( 2022 ) . Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions . Progress in Lipid Research vol. 86 , Article 101165 , 101165 - 101165 .
Dalli J, Gomez EA, Jouvene CC ( 2022 ) . Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease . Biomolecules vol. 12 , ( 3 ) 353 - 353 .
Mikroulis A, Ledri M, Ruffolo G, Palma E, Sperk G, Dalli J, Vezzani A, Kokaia M ( 2022 ) . Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor . The FASEB Journal vol. 36 , ( 3 )
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Montalvo Moreira SA, Rathod K, Chen J et al. ( 2022 ) . 20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin . British Journal of Pharmacology vol. 179 , ( 7 ) 1450 - 1469 .
De Matteis R, Flak MB, Gonzalez-Nunez M, Austin-Williams S, Palmas F, Colas RA, Dalli J ( 2022 ) . Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer . Science Advances vol. 8 , ( 5 ) Article eabl5420 ,
Kraft JD, Blomgran R, Bergström I, Soták M, Clark M, Rani A, Rajan MR, Dalli J et al. ( 2022 ) . Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis . The FASEB Journal vol. 36 , ( 3 )
Pistorius K, Souza PR, Gomez EA, Koenis DS, Rodriguez AR, Foster J, Sosabowski J, Hopkinson M et al. ( 2022 ) . MCTR3 reprogramming arthritic monocytes to exert pro-resolving and tissue-protective functions in inflammatory arthritis . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 103 , A5 - A6 .
Reinertsen AF, Primdahl KG, De Matteis R, Dalli J, Hansen TV ( 2021 ) . Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2<sub>n‐3 DPA</sub> . Chemistry – A European Journal vol. 28 , ( 7 ) Article e202103857 ,
Sogorb-Esteve A, Colas RA, Dalli J, Rohrer JD ( 2021 ) . Differential Lipid Mediator Involvement in the Different Forms of Genetic Frontotemporal Dementia: Novel Insights into Neuroinflammation . Journal of Alzheimer's Disease vol. 84 , ( 1 ) 283 - 289 .
Mikroulis A, Ledri M, Ruffolo G, Palma E, Sperk G, Dalli J, Vezzani A, Kokaia M ( 2021 ) . Lipid Mediator n-3 Docosapentaenoic Acid-Derived Protectin D1­(PD1n-3DPA) Enhances Synaptic Inhibition of Hippocampal Principal Neurons by Interaction with a G-Protein Coupled Receptor .
Beegun I, Koenis DS, Alusi G, Dalli J ( 2021 ) . Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis . Frontiers in Immunology vol. 12 , Article 733019 ,
Palmas F, Clarke J, Colas RA, Gomez EA, Keogh A, Boylan M, McEvoy N, McElvaney OJ et al. ( 2021 ) . Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients . PLOS ONE vol. 16 , ( 8 ) e0256226 - e0256226 .
Koenis DS, Beegun I, Jouvene CC, Aguirre GA, Souza PR, Gonzalez-Nunez M, Ly L, Pistorius K et al. ( 2021 ) . Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19 . Circulation Research vol. 129 , ( 4 )
Piattini F, Matsushita M, Muri J, Bretscher P, Feng X, Freigang S, Dalli J, Schneider C et al. ( 2021 ) . Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis . European Journal of Immunology vol. 51 , ( 10 ) 2417 - 2429 .
Jagusch H, Werner M, Koenis D, Dalli J, Werz O, Pohnert G ( 2021 ) . 14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae . ACS Pharmacology &amp; Translational Science vol. 4 , ( 3 ) 1188 - 1194 .
Marques RM, Gonzalez-Nunez M, Walker ME, Gomez EA, Colas RA, Montero-Melendez T, Perretti M, Dalli J ( 2021 ) . Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions . Cell Death &amp; Differentiation vol. 28 , ( 11 ) 3140 - 3160 .
Rossaint J, Thomas K, Mersmann S, Skupski J, Margraf A, Tekath T, Jouvene CC, Dalli J et al. ( 2021 ) . Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education . Journal of Experimental Medicine vol. 218 , ( 7 ) Article e20201353 ,
Félix‐Soriano E, Sáinz N, Gil‐Iturbe E, Collantes M, Fernández‐Galilea M, Castilla‐Madrigal R, Ly L, Dalli J et al. ( 2021 ) . Changes in brown adipose tissue lipid mediator signatures with aging, obesity, and DHA supplementation in female mice . The FASEB Journal vol. 35 , ( 6 ) Article e21592 ,
Keogh A, Clarke J, Rabani R, Dalli J, Curley GF ( 2021 ) . Lipoxin A4 as a Mediator of Mesenchymal Stromal Cell Therapeutic Effects in Pulmonary Sepsis . TP4. TP004 ARDS, SEPSIS, AND TRANSPLANTATION MECHANISTIC STUDIES . Conference: American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CAA1317 - A1317 .
Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N, Gomez EA, Gupta I et al. ( 2021 ) . Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs . Frontiers in Immunology vol. 12 , Article 649786 ,
Sobrino A, Walker ME, Colas RA, Dalli J ( 2020 ) . Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators . PLOS ONE vol. 15 , ( 12 ) e0242543 - e0242543 .
Wood EG, Macdougall CE, Blythe H, Clément M, Colas RA, Dalli J, Marelli-Berg F, Longhi MP ( 2020 ) . HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids . Scientific Reports vol. 10 , ( 1 ) Article 20825 ,
Colas RA, Gomez EA, Dalli J ( 2020 ) . Methodologies and Procedures Employed in the Identification and Quantitation of Lipid Mediators via LC-MS/MS .
Gomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C, Dalli J ( 2020 ) . Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis . Nature Communications vol. 11 , ( 1 ) Article 5420 ,
Souza PR, Walker ME, Goulding NJ, Dalli J, Perretti M, Norling LV ( 2020 ) . The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections . Frontiers in Immunology vol. 11 , Article 573019 ,
Brancaleone V, Dalli J, d’Emmanuele di Villa Bianca R, Pace S ( 2020 ) . Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders . Frontiers in Pharmacology vol. 11 , Article 585705 ,
Chen J, Purvis GSD, Collotta D, Al Zoubi S, Sugimoto MA, Cacace A, Martin L, Colas RA et al. ( 2020 ) . RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance . Frontiers in Immunology vol. 11 , Article 2080 ,
Schaller MS, Chen M, Colas RA, Sorrentino TA, Lazar AA, Grenon SM, Dalli J, Conte MS ( 2020 ) . Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease . Journal of the American Heart Association vol. 9 , ( 15 ) Article e016113 ,
Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J et al. ( 2020 ) . ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins . Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids vol. 1865 , ( 7 ) Article 158679 , 158679 - 158679 .
Allen BL, Montague-Cardoso K, Simeoli R, Colas RA, Oggero S, Vilar B, McNaughton PA, Dalli J et al. ( 2020 ) . Imbalance of proresolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis . Pain vol. 161 , ( 9 ) 2155 - 2166 .
Fussbroich D, Colas RA, Eickmeier O, Trischler J, Jerkic SP, Zimmermann K, Göpel A, Schwenger T et al. ( 2020 ) . A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA . Mucosal Immunology vol. 13 , ( 3 ) 481 - 492 .
Becares N, Härmälä S, China L, Colas RA, Maini AA, Bennet K, Skene SS, Shabir Z et al. ( 2020 ) . Immune Regulatory Mediators in Plasma from Patients With Acute Decompensation Are Associated With 3-Month Mortality . Clinical Gastroenterology and Hepatology vol. 18 , ( 5 ) 1207 - 1215.e6 .
Shivakoti R, Dalli J, Kadam D, Gaikwad S, Barthwal M, Colas RA, Mazzacuva F, Lokhande R et al. ( 2020 ) . Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes . Prostaglandins &amp; Other Lipid Mediators vol. 147 , Article 106398 , 106398 - 106398 .
Pangopoulos MK, Nolsøe JMN, Antonsen SG, Colas RA, Dalli J, Aursnes M, Stenstrøm Y, Hansen TV ( 2020 ) . Enzymatic studies with 3-oxa n-3 DPA . Bioorganic Chemistry vol. 96 , Article 103653 , 103653 - 103653 .
Määttänen P, Lurz E, Botts SR, Wu RY, Robinson SC, Yeung CW, Colas R, Li B et al. ( 2020 ) . Plant‐ and Fish‐Derived n‐3 PUFAs Suppress <i>Citrobacter Rodentium</i>–Induced Colonic Inflammation . Molecular Nutrition &amp; Food Research vol. 64 , ( 6 ) Article 1900873 ,
Sønderskov J, Tungen JE, Palmas F, Dalli J, Serhan CN, Stenstrøm Y, Vidar Hansen T ( 2020 ) . Stereoselective synthesis of MaR2n-3 DPA . Tetrahedron Letters vol. 61 , ( 7 ) Article 151510 , 151510 - 151510 .
Wilcz‐Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R et al. ( 2020 ) . Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway . EMBO Molecular Medicine vol. 12 , ( 2 ) Article e10491 ,
Souza PR, Marques RM, Gomez EA, Colas RA, De Matteis R, Zak A, Patel M, Collier DJ et al. ( 2020 ) . Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses . Circulation Research vol. 126 , ( 1 ) 75 - 90 .
Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV et al. ( 2020 ) . A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice . Journal of Neurotrauma vol. 37 , ( 1 ) 66 - 79 .
Plebani R, Colas RA, Mattoscio D, Trerotola M, Gomez EA, Isopi E, Castagnozzi S, Dalli J et al. ( 2020 ) . CFTR ABLATION BY CRISPR/CAS9 IMPAIRS THE PRODUCTION OF PRO-RESOLVING LIPID MEDIATORS BY HUMAN AIRWAY EPITHELIAL CELLS . PEDIATRIC PULMONOLOGY . vol. 55 , S75 - S75 .
Flak MB, Koenis DS, Sobrino A, Smith J, Pistorius K, Palmas F, Dalli J ( 2019 ) . GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections . Journal of Clinical Investigation vol. 130 , ( 1 ) 359 - 373 .
Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN et al. ( 2019 ) . Addendum: Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1<sub><i>n</i>−3 DPA</sub> . Chemistry – A European Journal vol. 25 , ( 66 ) 15212 - 15212 .
Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C et al. ( 2019 ) . Proresolving Mediators LXB4 and RvE1 Regulate Inflammation in Stromal Cells from Patients with Shoulder Tendon Tears . The American Journal of Pathology vol. 189 , ( 11 ) 2258 - 2268 .
Colas RA, Nhat LTH, Thuong NTT, Gómez EA, Ly L, Thanh HH, Mai NTH, Phu NH et al. ( 2019 ) . Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis . The FASEB Journal vol. 33 , ( 11 ) 13028 - 13039 .
Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R et al. ( 2019 ) . Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells . Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids vol. 1864 , ( 10 ) 1350 - 1362 .
Dalli J, Pistorius K, Walker ME ( 2019 ) . Novel n-3 Docosapentaneoic Acid-Derived Pro-resolving Mediators Are Vasculoprotective and Mediate the Actions of Statins in Controlling Inflammation . 65 - 75 .
Nesman JI, Gangestad Primdahl K, Tungen JE, Palmas F, Dalli J, Hansen TV ( 2019 ) . Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA . Molecules vol. 24 , ( 18 ) 3228 - 3228 .
Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE et al. ( 2019 ) . Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction . eBioMedicine vol. 46 , 264 - 273 .
Valkonen S, Holopainen M, Colas RA, Impola U, Dalli J, Käkelä R, Siljander PR-M, Laitinen S ( 2019 ) . Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules . Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids vol. 1864 , ( 8 ) 1168 - 1182 .
Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J, Pitzalis C ( 2019 ) . Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis . JCI Insight vol. 4 , ( 13 ) Article e125191 ,
Dakin SG, Colas RA, Dean BJF, Wheway K, Watkins B, Dalli J, Carr AJ ( 2019 ) . Tendon cells isolated from patients with persistent shoulder tendinopathy show dysregulated resolution responses . Translational Sports Medicine vol. 2 , ( 4 ) 173 - 176 .
Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J et al. ( 2019 ) . Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock . Annals of Surgery vol. 273 , ( 5 ) 1012 - 1021 .
Colas RA, Nhat LTH, Thuong NTT, Cifuentes EAG, Ly L, Thanh HH, Phu NH, Mai NTH et al. ( 2019 ) . Pro-Resolving Mediator Profiles And 5-Lipoxygenase Activity In Cerebrospinal Fluid Correlate with Disease Severity and Outcome in Adults with Tuberculous Meningitis .
Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C et al. ( 2019 ) . Proresolving mediators LXB<sub>4</sub> and RvE1 regulate inflammation in stromal cells from patients with shoulder tendon tears .
Becares N, Maini AA, Colas RA, Dalli J, Gilroy DW, O’brien A ( 2019 ) . FRI-109-Increased plasma leukotriene B4 in decompensated cirrhosis associates with disease progression and leads to increased skin window neutrophil infiltration . Journal of Hepatology . vol. 70 , e435 - e435 .
Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al. ( 2019 ) . 15‐Epi‐Lxa\n <sub>4</sub>\n and MaR1 counter inflammation in stromal cells from patients with Achilles tendinopathy and rupture . The FASEB Journal vol. 33 , ( 7 ) 8043 - 8054 .
López-Vicario C, Titos E, Walker ME, Alcaraz-Quiles J, Casulleras M, Durán-Güell M, Flores-Costa R, Pérez-Romero N et al. ( 2019 ) . Leukocytes from obese individuals exhibit an impaired SPM signature . The FASEB Journal vol. 33 , ( 6 ) 7072 - 7083 .
Colas RA, Thwaites GE, Thuong NT, Ly L, Phu NH, Ramakrishnan L, Mai NT, Dalli J ( 2019 ) . Pro-resolving mediator profiles and 5-lipoxygenase activity in cerebrospinal fluids correlate with disease severity and outcomes in adults with tuberculosis meningitis . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 85 , 1639 - 1639 .
Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al. ( 2019 ) . Proresolving mediators counter inflammation in stromal cells from patients with Achilles tendon disease . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 100 , A15 - A15 .
Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN et al. ( 2018 ) . Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1<sub><i>n</i>−3 DPA</sub> . Chemistry – A European Journal vol. 25 , ( 6 ) 1476 - 1480 .
Serhan CN, Chiang N, Dalli J ( 2018 ) . New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration . Molecular Aspects of Medicine vol. 64 , 1 - 17 .
Laguna-Fernandez A, Checa A, Carracedo M, Artiach G, Petri MH, Baumgartner R, Forteza MJ, Jiang X et al. ( 2018 ) . ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages . Circulation vol. 138 , ( 16 ) 1693 - 1705 .
Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K et al. ( 2018 ) . n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis . Brain
Dalli J, Serhan CN ( 2018 ) . Identification and structure elucidation of the pro‐resolving mediators provides novel leads for resolution pharmacology . British Journal of Pharmacology vol. 176 , ( 8 ) 1024 - 1037 .
Pistorius K, Souza PR, De Matteis R, Austin-Williams S, Primdahl KG, Vik A, Mazzacuva F, Colas RA et al. ( 2018 ) . PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function . Cell Chemical Biology vol. 25 , ( 6 ) 749 - 760.e9 .
China L, Maini A, Skene SS, Shabir Z, Sylvestre Y, Colas RA, Ly L, Becares Salles N et al. ( 2018 ) . Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease . Clinical Gastroenterology and Hepatology vol. 16 , ( 5 ) 738 - 747.e7 .
Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F et al. ( 2018 ) . Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2 . Infection and Immunity vol. 86 , ( 4 ) Article e00688-17 ,
Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RPH, Serhan CN et al. ( 2018 ) . Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli–driven acute inflammation . JCI Insight vol. 3 , ( 6 ) Article e94463 ,
Colas RA, Souza PR, Walker ME, Burton M, Zasłona Z, Curtis AM, Marques RM, Dalli J ( 2018 ) . Impaired Production and Diurnal Regulation of Vascular RvD\n <sub>n-3 DPA</sub>\n Increase Systemic Inflammation and Cardiovascular Disease . Circulation Research vol. 122 , ( 6 ) 855 - 863 .
Chiang N, Riley IR, Dalli J, Rodriguez AR, Spur BW, Serhan CN ( 2018 ) . New maresin conjugates in tissue regeneration pathway counters leukotriene D<sub>4</sub>–stimulated vascular responses . The FASEB Journal vol. 32 , ( 7 ) 4043 - 4052 .
Mai NTH, Dobbs N, Phu NH, Colas RA, Thao LTP, Thuong NTT, Nghia HDT, Hanh NHH et al. ( 2018 ) . A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults . eLife vol. 7 , Article e33478 ,
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al. ( 2018 ) . Endogenously generated arachidonate‐derived ligands for TRPV1 induce cardiac protection in sepsis . The FASEB Journal vol. 32 , ( 7 ) 3816 - 3831 .
Dalli J, Serhan CN ( 2018 ) . Immunoresolvents signaling molecules at intersection between the brain and immune system . Current Opinion in Immunology vol. 50 , 48 - 54 .
Dalli J, Colas R, de Souza PRS ( 2018 ) . Impaired Production and Diurnal Regulation of Vascular RvD<sub>n-3</sub> DPA Increases Systemic Inflammation and Cardiovascular Disease . AMERICAN JOURNAL OF PATHOLOGY . vol. 188 , 2409 - 2409 .
Dalli J, Colas RA, Walker ME, Serhan CN ( 2018 ) . Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis . 59 - 72 .
Dalli J ( 2018 ) . Omega-3 Fatty Acids and Resolution of Inflammation . ANNALS OF NUTRITION AND METABOLISM . vol. 73 , 190 - 190 .
Dalli J ( 2017 ) . Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections? . Molecular Aspects of Medicine vol. 58 , 12 - 20 .
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al. ( 2017 ) . Resolvins suppress tumor growth and enhance cancer therapy . Journal of Experimental Medicine vol. 215 , ( 1 ) 115 - 140 .
Dalli J, Serhan CN ( 2017 ) . Pro-Resolving Mediators in Regulating and Conferring Macrophage Function . Frontiers in Immunology vol. 8 , Article 1400 ,
Hansen TV, Dalli J, Serhan CN ( 2017 ) . The novel lipid mediator PD1n-3 DPA: An overview of the structural elucidation, synthesis, biosynthesis and bioactions . Prostaglandins &amp; Other Lipid Mediators vol. 133 , 103 - 110 .
Motwani MP, Newson J, Kwong S, Richard-Loendt A, Colas R, Dalli J, Gilroy DW ( 2017 ) . Prolonged immune alteration following resolution of acute inflammation in humans . PLOS ONE vol. 12 , ( 10 ) e0186964 - e0186964 .
Walker ME, Souza PR, Colas RA, Dalli J ( 2017 ) . 13‐Series resolvins mediate the leukocyte‐platelet actions of atorvastatin and pravastatin in inflammatory arthritis . The FASEB Journal vol. 31 , ( 8 ) 3636 - 3648 .
Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon J-S, Shinohara M et al. ( 2017 ) . NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B<sub>4</sub>Synthesis . American Journal of Respiratory and Critical Care Medicine vol. 196 , ( 6 ) 713 - 726 .
Dakin SG, Ly L, Colas RA, Oppermann U, Wheway K, Watkins B, Dalli J, Carr AJ ( 2017 ) . Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy . Scientific Reports vol. 7 , ( 1 ) Article 11009 ,
Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J et al. ( 2017 ) . Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming . Nature Biomedical Engineering vol. 1 , ( 7 ) Article 0094 ,
Vik A, Dalli J, Hansen TV ( 2017 ) . Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid . Bioorganic &amp; Medicinal Chemistry Letters vol. 27 , ( 11 ) 2259 - 2266 .
Perretti M, Di Filippo C, D’Amico M, Dalli J ( 2017 ) . Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide . PLOS ONE vol. 12 , ( 4 ) e0175786 - e0175786 .
Gobbetti T, Dalli J, Colas RA, Federici Canova D, Aursnes M, Bonnet D, Alric L, Vergnolle N et al. ( 2017 ) . Protectin D1\n <sub>n-3 DPA</sub>\n and resolvin D5\n <sub>n-3 DPA</sub>\n are effectors of intestinal protection . Proceedings of the National Academy of Sciences vol. 114 , ( 15 ) 3963 - 3968 .
Norling LV, Ly L, Dalli J ( 2017 ) . Resolving inflammation by using nutrition therapy . Current Opinion in Clinical Nutrition &amp; Metabolic Care vol. 20 , ( 2 ) 145 - 152 .
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. ( 2017 ) . Sex differences in the inflammatory response and inflammation-induced vascular dysfunction . The Lancet . vol. 389 , S20 - S20 .
Freire MO, Dalli J, Serhan CN, Van Dyke TE ( 2017 ) . Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes . The Journal of Immunology vol. 198 , ( 2 ) 718 - 728 .
Dalli J, Serhan C ( 2017 ) . Macrophage Proresolving Mediators-the When and Where . Myeloid Cells in Health and Disease , ASM Press
Perretti M, Cooper D, Dalli J, Norling LV ( 2017 ) . Immune resolution mechanisms in inflammatory arthritis . Nature Reviews Rheumatology vol. 13 , ( 2 ) 87 - 99 .
Dalli J, Colas RA, Quintana C, Barragan-Bradford D, Hurwitz S, Levy BD, Choi AM, Serhan CN et al. ( 2017 ) . Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes . Critical Care Medicine vol. 45 , ( 1 ) 58 - 68 .
Frigerio F, Colas R, Marchini S, van Vliet E, Foerch P, Aronica E, Perretti M, Dalli J et al. ( 2017 ) . PRORESOLVING ANTIINFLAMMATORY MECHANISMS ARE NOVEL POTENTIAL TARGETS AGAINST EPILEPTOGENESIS . EPILEPSIA . vol. 58 , S5 - S5 .
China L, Maini A, Colas R, Ly L, Dalli J, Gilroy D, O'Brien A ( 2017 ) . Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities . JOURNAL OF HEPATOLOGY . vol. 66 , S390 - S390 .
Primdahl KG, Tungen JE, De Souza PRS, Colas RA, Dalli J, Hansen TV, Vik A ( 2017 ) . Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PD<sub>n-3 DPA</sub> . Org. Biomol. Chem. vol. 15 , ( 40 ) 8606 - 8613 .
Dalli J, Colas RA, Arnardottir H, Serhan CN ( 2017 ) . Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution . Immunity vol. 46 , ( 1 ) 92 - 105 .
Tsoyi K, Hall SRR, Dalli J, Colas RA, Ghanta S, Ith B, Coronata A, Fredenburgh LE et al. ( 2016 ) . Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators* . Critical Care Medicine vol. 44 , ( 12 ) e1236 - e1245 .
Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR, Serhan CN ( 2016 ) . Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation . The Journal of Immunology vol. 197 , ( 11 ) 4444 - 4452 .
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al. ( 2016 ) . Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans . Journal of Clinical Investigation vol. 127 , ( 1 ) 169 - 182 .
Titos E, Rius B, López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Lopategi A, Dalli J, Lozano JJ et al. ( 2016 ) . Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue . The Journal of Immunology vol. 197 , ( 8 ) 3360 - 3370 .
Dalli J, Vlasakov I, Riley IR, Rodriguez AR, Spur BW, Petasis NA, Chiang N, Serhan CN ( 2016 ) . Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages . Proceedings of the National Academy of Sciences vol. 113 , ( 43 ) 12232 - 12237 .
Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV, Vik A ( 2016 ) . Synthesis of 13(<i>R</i>)-Hydroxy-7<i>Z</i>,10<i>Z</i>,13<i>R</i>,14<i>E</i>,16<i>Z</i>,19<i>Z</i> Docosapentaenoic Acid (13<i>R</i>-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins . Journal of Natural Products vol. 79 , ( 10 ) 2693 - 2702 .
Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN ( 2016 ) . Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation . The Journal of Immunology vol. 197 , ( 6 ) 2362 - 2368 .
Abdulnour RE, Sham HP, Douda DN, Colas RA, Dalli J, Bai Y, Ai X, Serhan CN et al. ( 2016 ) . Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation . Mucosal Immunology vol. 9 , ( 5 ) 1278 - 1287 .
Chiurchiù V, Leuti A, Dalli J, Jacobsson A, Battistini L, Maccarrone M, Serhan CN ( 2016 ) . Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses . Science Translational Medicine vol. 8 , ( 353 )
Colby JK, Abdulnour R-EE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B et al. ( 2016 ) . Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia . The American Journal of Pathology vol. 186 , ( 7 ) 1801 - 1813 .
Dalli J, Chiang N, Serhan C ( 2016 ) . AB0042 Identification of Sulfido-Conjugated Mediators That Promote Resolution of Infection and Organ Protection . Annals of the Rheumatic Diseases vol. 75 , 911 - 911 .
Norling L, Headland S, Dalli J, Arnardottir H, Jones H, Haworth O, Serhan C, Perretti M ( 2016 ) . SAT0026 Pro-Resolving and Cartilage-Protective Actions of Resolvin D1 in Inflammatory Arthritis . Annals of the Rheumatic Diseases . vol. 75 , 673 - 673 .
Dalli J, Serhan C ( 2016 ) . Macrophage Proresolving Mediators—the When and Where . Microbiology Spectrum vol. 4 , ( 3 ) Article 4.3.21 ,
Arnardottir H, Orr SK, Dalli J, Serhan CN ( 2016 ) . Human milk proresolving mediators stimulate resolution of acute inflammation . Mucosal Immunology vol. 9 , ( 3 ) 757 - 766 .
Elajami TK, Colas RA, Dalli J, Chiang N, Serhan CN, Welty FK ( 2016 ) . Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling . The FASEB Journal vol. 30 , ( 8 ) 2792 - 2801 .
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al. ( 2016 ) . Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis . JCI Insight vol. 1 , ( 5 )
Dalli J ( 2016 ) . Lipid mediators and the resolution of chronic inflammation: implications for arthritis therapy . Osteoarthritis and Cartilage vol. 24 , S2 - S2 .
Ramon S, Dalli J, Sanger JM, Winkler JW, Aursnes M, Tungen JE, Hansen TV, Serhan CN ( 2016 ) . The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation . The American Journal of Pathology vol. 186 , ( 4 ) 962 - 973 .
Wang C-W, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE et al. ( 2016 ) . Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes . Infection and Immunity vol. 84 , ( 3 ) 658 - 665 .
Dalli J, Sanger JM, Rodriguez AR, Chiang N, Spur BW, Serhan CN ( 2016 ) . Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3 . PLOS ONE vol. 11 , ( 2 ) e0149319 - e0149319 .
Winkler JW, Orr SK, Dalli J, Cheng C-YC, Sanger JM, Chiang N, Petasis NA, Serhan CN ( 2016 ) . Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance . Scientific Reports vol. 6 , ( 1 ) Article 18972 ,
Hansen TV, Dalli J, Serhan CN ( 2016 ) . Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double di-oxygenation isomers . RSC Advances vol. 6 , ( 34 ) 28820 - 28829 .
Fiala M, Terrando N, Dalli J ( 2016 ) . Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment . Journal of Alzheimer's Disease vol. 49 , ( 4 ) 1191 - 1191 .
Cianci E, Recchiuti A, Trubiani O, Diomede F, Marchisio M, Miscia S, Colas RA, Dalli J et al. ( 2015 ) . Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins . Stem Cells Translational Medicine vol. 5 , ( 1 ) 20 - 32 .
Aursnes M, Tungen JE, Colas RA, Vlasakov I, Dalli J, Serhan CN, Hansen TV ( 2015 ) . Synthesis of the 16<i>S</i>,17<i>S</i>-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages . Journal of Natural Products vol. 78 , ( 12 ) 2924 - 2931 .
Croasdell A, Thatcher TH, Kottmann RM, Colas RA, Dalli J, Serhan CN, Sime PJ, Phipps RP ( 2015 ) . Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages . American Journal of Physiology-Lung Cellular and Molecular Physiology vol. 309 , ( 8 ) L888 - L901 .
Fiala M, Terrando N, Dalli J ( 2015 ) . Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment . Journal of Alzheimer's Disease vol. 48 , ( 2 ) 293 - 301 .
Dalli J, Kraft BD, Colas RA, Shinohara M, Fredenburgh LE, Hess DR, Chiang N, Welty-Wolf K et al. ( 2015 ) . The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide . American Journal of Respiratory Cell and Molecular Biology vol. 53 , ( 3 ) 314 - 325 .
Dalli J, Chiang N, Serhan CN ( 2015 ) . Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections . Nature Medicine vol. 21 , ( 9 ) 1071 - 1075 .
Chiang N, Dalli J, Colas RA, Serhan CN ( 2015 ) . Identification of resolvin D2 receptor mediating resolution of infections and organ protection . Journal of Experimental Medicine vol. 212 , ( 8 ) 1203 - 1217 .
Börgeson E, Johnson AMF, Lee YS, Till A, Syed GH, Ali-Shah ST, Guiry PJ, Dalli J et al. ( 2015 ) . Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease . Cell Metabolism vol. 22 , ( 1 ) 125 - 137 .
Kain V, Ingle KA, Colas RA, Dalli J, Prabhu SD, Serhan CN, Joshi M, Halade GV ( 2015 ) . Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function . Journal of Molecular and Cellular Cardiology vol. 84 , 24 - 35 .
Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM, Barillas-Mury C ( 2015 ) . A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae . Nature Communications vol. 6 , ( 1 ) Article 7403 ,
Krishnamoorthy N, Burkett P, Dalli J, Abdulnour R-E, Colas R, Ramon S, Phipps R, Petasis N et al. ( 2015 ) . Maresin-1 regulates type 2 innate lymphoid cells and promotes generation of regulatory T cells to limit allergic inflammation (HYP2P.336) . The Journal of Immunology vol. 194 , ( 1_Supplement ) 53.17 - 53.17 .
Orr SK, Colas RA, Dalli J, Chiang N, Serhan CN ( 2015 ) . Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent . American Journal of Physiology-Lung Cellular and Molecular Physiology vol. 308 , ( 9 ) L904 - L911 .
Serhan CN, Chiang N, Dalli J ( 2015 ) . The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution . Seminars in Immunology vol. 27 , ( 3 ) 200 - 215 .
Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Canova DF, Perretti M, Brunelleschi S ( 2015 ) . Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen . Life Sciences vol. 126 , 28 - 36 .
Ramon S, Dalli J, Norris P, Colas R, Serhan C ( 2015 ) . Elucidation of Resolvin and Protectin Sulfido‐Conjugated Mediators: New Pro‐Resolving and Tissue Regenerative Pathways . The FASEB Journal vol. 29 , ( S1 ) Article LB423 ,
Arnardottir H, Orr S, Dalli J, Serhan C ( 2015 ) . Human Milk Stimulates Resolution of Acute Inflammation . The FASEB Journal vol. 29 , ( S1 ) Article 913.14 ,
Dalli J, Chiang N, Serhan C ( 2015 ) . Novel Peptide‐Conjugated Maresins Stimulate Tissue Regeneration and Clearance of Infections in Planaria and Inflammatory Exudates . The FASEB Journal vol. 29 , ( S1 ) Article 285.5 ,
Serhan CN, Dalli J, Colas RA, Winkler JW, Chiang N ( 2015 ) . Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome . Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids vol. 1851 , ( 4 ) 397 - 413 .
Winkler J, Orr S, Dalli J, Chiang N, Petasis N, Serhan C ( 2015 ) . Resolvin D4 Potent Antiiinflammatory Proresolving Actions Confirmed via Total Synthesis . The FASEB Journal vol. 29 , ( S1 ) Article 285.10 ,
Sulciner M, Mudge D, Ramon S, Dalli J, Kieran M, Huang S, Serhan C, Panigrahy D ( 2015 ) . Suppression of Cell Debris‐Stimulated Tumor Growth by Resolvin Mediated Clearance . The FASEB Journal vol. 29 , ( S1 ) Article 926.14 ,
Dalli J, Ramon S, Norris PC, Colas RA, Serhan CN ( 2015 ) . Novel proresolving and tissue‐regenerative resolvin and protectin sulfido‐conjugated pathways . The FASEB Journal vol. 29 , ( 5 ) 2120 - 2136 .
Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour R-EE, Colas R, Ramon S, Phipps RP, Petasis NA et al. ( 2015 ) . Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation . The Journal of Immunology vol. 194 , ( 3 ) 863 - 867 .
Shinohara M, Kibi M, Riley IR, Chiang N, Dalli J, Kraft BD, Piantadosi CA, Choi AMK et al. ( 2014 ) . Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1 . American Journal of Physiology-Lung Cellular and Molecular Physiology vol. 307 , ( 10 ) L746 - L757 .
Van Dyke TE, Hasturk H, Kantarci A, Freire MO, Nguyen D, Dalli J, Serhan CN ( 2014 ) . Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis . Journal of Dental Research vol. 94 , ( 1 ) 148 - 156 .
Abdulnour R-EE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA et al. ( 2014 ) . Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective . Proceedings of the National Academy of Sciences vol. 111 , ( 46 ) 16526 - 16531 .
Serhan CN, Chiang N, Dalli J, Levy BD ( 2014 ) . Lipid Mediators in the Resolution of Inflammation . Cold Spring Harbor Perspectives in Biology vol. 7 , ( 2 ) a016311 - a016311 .
Dalli J, Colas RA, Serhan CN ( 2014 ) . Correction: Corrigendum: Novel n-3 Immunoresolvents: Structures and Actions . Scientific Reports vol. 4 , ( 1 ) Article 6726 ,
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Cover Picture: Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1<sub><i>n</i>−3 DPA</sub> Utilizing an sp<sup>3</sup>–sp<sup>3</sup> Negishi Cross‐Coupling Reaction (Chem. Eur. J. 45/2014) . Chemistry – A European Journal vol. 20 , ( 45 ) 14533 - 14533 .
Dalli J, Chiang N, Serhan CN ( 2014 ) . Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection . Proceedings of the National Academy of Sciences vol. 111 , ( 44 )
Arnardottir HH, Dalli J, Colas RA, Shinohara M, Serhan CN ( 2014 ) . Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines . The Journal of Immunology vol. 193 , ( 8 ) 4235 - 4244 .
Frediani JK, Jones DP, Tukvadze N, Uppal K, Sanikidze E, Kipiani M, Tran VT, Hebbar G et al. ( 2014 ) . Plasma Metabolomics in Human Pulmonary Tuberculosis Disease: A Pilot Study . PLoS ONE vol. 9 , ( 10 ) e108854 - e108854 .
Mudge D, Kieran MW, Bielenberg D, Benny O, Dalli J, Huang S, Serhan CN, Panigrahy D ( 2014 ) . Abstract 1170: Maresin 1: a potent endogenous anti-inflammatory and pro-resolving inhibitor of primary tumor growth and metastasis . Cancer Research . vol. 74 , 1170 - 1170 .
Sulciner ML, Mudge DK, Bielenberg DR, Benny O, Dalli J, Huang S, Serhan CN, Kieran MW et al. ( 2014 ) . Abstract 1664: Cancer progression: The failure to resolve . Cancer Research . vol. 74 , 1664 - 1664 .
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1<sub><i>n</i>−3 DPA</sub> Utilizing an sp<sup>3</sup>–sp<sup>3</sup> Negishi Cross‐Coupling Reaction . Chemistry – A European Journal vol. 20 , ( 45 ) 14537 - 14537 .
Tungen JE, Aursnes M, Vik A, Ramon S, Colas RA, Dalli J, Serhan CN, Hansen TV ( 2014 ) . Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1 . Journal of Natural Products vol. 77 , ( 10 ) 2241 - 2247 .
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1<sub><i>n</i>−3 DPA</sub> Utilizing an sp<sup>3</sup>–sp<sup>3</sup> Negishi Cross‐Coupling Reaction . Chemistry – A European Journal vol. 20 , ( 45 ) 14575 - 14578 .
Serhan CN, Chiang N, Dalli J ( 2014 ) . Macrophages and the Entrance of Resolution Phase Lipid Mediators . Macrophages: Biology and Role in the Pathology of Diseases , Springer New York
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M ( 2014 ) . 15. Neutrophils in GCA . Rheumatology vol. 53 , ( suppl 2 ) i9 - i9 .
Deng B, Wang C-W, Arnardottir HH, Li Y, Cheng C-YC, Dalli J, Serhan CN ( 2014 ) . Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages . PLoS ONE vol. 9 , ( 7 ) e102362 - e102362 .
McCauley LK, Dalli J, Koh AJ, Chiang N, Serhan CN ( 2014 ) . Cutting Edge: Parathyroid Hormone Facilitates Macrophage Efferocytosis in Bone Marrow via Proresolving Mediators Resolvin D1 and Resolvin D2 . The Journal of Immunology vol. 193 , ( 1 ) 26 - 29 .
Colas RA, Shinohara M, Dalli J, Chiang N, Serhan CN ( 2014 ) . Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue . American Journal of Physiology-Cell Physiology vol. 307 , ( 1 ) C39 - C54 .
Aursnes M, Tungen JE, Vik A, Dalli J, Hansen TV ( 2014 ) . ChemInform Abstract: Stereoselective Synthesis of Protectin D1: A Potent Antiinflammatory and Proresolving Lipid Mediator . ChemInform vol. 45 , ( 26 ) Article chin.201426218 ,
Mirakaj V, Dalli J, Granja T, Rosenberger P, Serhan CN ( 2014 ) . Vagus nerve controls resolution and pro-resolving mediators of inflammation . Journal of Experimental Medicine vol. 211 , ( 6 ) 1037 - 1048 .
Headland S, Norling L, Patel H, Dalli J, Kelly S, Pitzalis C, Dell'Accio F, Perretti M ( 2014 ) . A novel mechanism for protecting the arthritic joint: microparticles deliver Annexin A1 into cartilage (146.8) . The FASEB Journal . vol. 28 ,
Frediani J, Jones D, Tukvadze N, Sanikidze E, Kipiani M, Uppal K, Kurani S, Hebbar G et al. ( 2014 ) . Plasma high‐resolution metabolomic profiling reveals upregulation of specific resolvins in patients with pulmonary tuberculosis (248.3) . The FASEB Journal vol. 28 , ( S1 ) Article 248.3 ,
Norling L, Headland S, Dalli J, Serhan C, Perretti M ( 2014 ) . Resolvin D1 protects from neutrophil mediated joint destruction in inflammatory arthritis (146.5) . The FASEB Journal . vol. 28 ,
Aursnes M, Tungen JE, Vik A, Colas R, Cheng C-YC, Dalli J, Serhan CN, Hansen TV ( 2014 ) . Total Synthesis of the Lipid Mediator PD1<sub>n-3 DPA</sub>: Configurational Assignments and Anti-inflammatory and Pro-resolving Actions . Journal of Natural Products vol. 77 , ( 4 ) 910 - 916 .
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M ( 2014 ) . Investigational Analysis Reveals a Potential Role for Neutrophils in Giant-Cell Arteritis Disease Progression . Circulation Research vol. 114 , ( 2 ) 242 - 248 .
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M ( 2014 ) . NEUTROPHILS IN GCA . RHEUMATOLOGY . vol. 53 , 9 - 9 .
Aursnes M, Tungen JE, Vik A, Dalli J, Hansen TV ( 2014 ) . Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator . Org. Biomol. Chem. vol. 12 , ( 3 ) 432 - 437 .
Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Total Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator MaR1<sub>n-3DPA</sub> Utilizing an sp<SUP>3</SUP>-sp<SUP>3</SUP> Negishi Cross-Coupling Reaction . CHEMISTRY-A EUROPEAN JOURNAL vol. 20 , ( 45 ) 14575 - 14578 .
Dalli J, Norling LV, Montero‐Melendez T, Canova DF, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al. ( 2013 ) . Microparticle alpha‐2‐macroglobulin enhances pro‐resolving responses and promotes survival in sepsis . EMBO Molecular Medicine vol. 6 , ( 1 ) 27 - 42 .
Li Y, Dalli J, Chiang N, Baron RM, Quintana C, Serhan CN ( 2013 ) . Plasticity of Leukocytic Exudates in Resolving Acute Inflammation Is Regulated by MicroRNA and Proresolving Mediators . Immunity vol. 39 , ( 5 ) 885 - 898 .
Divanovic S, Dalli J, Jorge-Nebert LF, Flick LM, Gálvez-Peralta M, Boespflug ND, Stankiewicz TE, Fitzgerald JM et al. ( 2013 ) . Contributions of the Three CYP1 Monooxygenases to Pro-Inflammatory and Inflammation-Resolution Lipid Mediator Pathways . The Journal of Immunology vol. 191 , ( 6 ) 3347 - 3357 .
Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M ( 2013 ) . Heterogeneity in Neutrophil Microparticles Reveals Distinct Proteome and Functional Properties . Molecular &amp; Cellular Proteomics vol. 12 , ( 8 ) 2205 - 2219 .
Norling LV, Dalli J ( 2013 ) . Microparticles are novel effectors of immunity . Current Opinion in Pharmacology vol. 13 , ( 4 ) 570 - 575 .
Chiang N, Shinohara M, Dalli J, Mirakaj V, Kibi M, Choi AMK, Serhan CN ( 2013 ) . Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits . The Journal of Immunology vol. 190 , ( 12 ) 6378 - 6388 .
Dalli J, Consalvo AP, Ray V, Di Filippo C, D’Amico M, Mehta N, Perretti M ( 2013 ) . Proresolving and Tissue-Protective Actions of Annexin A1–Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor . The Journal of Immunology vol. 190 , ( 12 ) 6478 - 6487 .
Dalli J, Colas RA, Serhan CN ( 2013 ) . Novel n-3 Immunoresolvents: Structures and Actions . Scientific Reports vol. 3 , ( 1 ) Article 1940 ,
Gao F, Dalli J, Claria J, Serhan CN ( 2013 ) . <i>E. coli</i> peritonitis initiates D‐series Resolvin‐metabolome . The FASEB Journal vol. 27 , ( S1 )
Shinohara M, Chiang N, Dalli J, Mirakaj V, Choi AMK, Serhan CN ( 2013 ) . Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Novel Pro‐resolving Mediators and Heme Oxygenase‐1 . The FASEB Journal vol. 27 , ( S1 )
Dalli J, Karamnov S, Zhu M, Petasis N, Serhan CN ( 2013 ) . Maresin 1 a Novel Macrophage n‐3 Derived Mediator is a Potent Tissue Regenerative Immunoresolvent . The FASEB Journal vol. 27 , ( S1 )
Perretti M, Dalli J, Norling LV, Melendez TM, Hinds C ( 2013 ) . Neutrophil Microparticles are heterogenous in content and function . The FASEB Journal . vol. 27 ,
Dalli J, Serhan C ( 2013 ) . Pro‐Resolving Mediator Production by Human Phagocytes and their Transcellular Biosynthesis with Microparticles in Inflammation‐Resolution . The FASEB Journal vol. 27 , ( S1 )
Li Y, Fredman G, Dalli J, Chiang N, Serhan CN ( 2013 ) . Temporal Regulation of Pro‐Resolving Mediators and MicroRNA in Self‐Limited versus Delayed Resolution of Acute Inflammation . The FASEB Journal vol. 27 , ( S1 )
Dalli J, Zhu M, Vlasenko NA, Deng B, Haeggström JZ, Petasis NA, Serhan CN ( 2013 ) . The novel 13<i>S</i>,14<i>S</i>‐epoxy‐maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A<sub>4</sub>hydrolase (LTA<sub>4</sub>H), and shifts macrophage phenotype . The FASEB Journal vol. 27 , ( 7 ) 2573 - 2583 .
Dalli J, Winkler JW, Colas RA, Arnardottir H, Cheng C-YC, Chiang N, Petasis NA, Serhan CN ( 2013 ) . Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents . Chemistry &amp; Biology vol. 20 , ( 2 ) 188 - 201 .
Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M, Wheatley C ( 2013 ) . Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1<mml:math xmlns:mml=\http://www.w3.org/1998/Math/MathML\ id=\M1\><mml:mrow><mml:mi mathvariant=\bold-italic\>β</mml:mi></mml:mrow></mml:math>, TNF-<mml:math xmlns:mml=\http://www.w3.org/1998/Math/MathML\ id=\M2\><mml:mrow><mml:mi mathvariant=\bold-italic\>α</mml:mi></mml:mrow></mml:math>, IL-6, and HMGB1 Expression . Mediators of Inflammation vol. 2013 , 1 - 20 .
Montero-Melendez T, Dalli J, Perretti M ( 2012 ) . Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors . Cell Death &amp; Differentiation vol. 20 , ( 4 ) 567 - 575 .
Jones CN, Dalli J, Dimisko L, Wong E, Serhan CN, Irimia D ( 2012 ) . Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions . Proceedings of the National Academy of Sciences vol. 109 , ( 50 ) 20560 - 20565 .
Giera M, Ioan-Facsinay A, Toes R, Gao F, Dalli J, Deelder AM, Serhan CN, Mayboroda OA ( 2012 ) . Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS . Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids vol. 1821 , ( 11 ) 1415 - 1424 .
Dalli J, Serhan CN ( 2012 ) . Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators . Blood vol. 120 , ( 15 ) e60 - e72 .
Fredman G, Li Y, Dalli J, Chiang N, Serhan CN ( 2012 ) . Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA . Scientific Reports vol. 2 , ( 1 ) Article 639 ,
Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G, Lucattelli M ( 2012 ) . Genetic Ablation of the <i>Fpr1</i> Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice . American Journal of Respiratory Cell and Molecular Biology vol. 47 , ( 3 ) 332 - 339 .
Clària J, Dalli J, Yacoubian S, Gao F, Serhan CN ( 2012 ) . Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat . The Journal of Immunology vol. 189 , ( 5 ) 2597 - 2605 .
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M ( 2012 ) . Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 32 , ( 8 ) 1970 - 1978 .
Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, Mietton F, Matteoli G et al. ( 2012 ) . Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages . Proceedings of the National Academy of Sciences vol. 109 , ( 42 )
Lucattelli M, Cardini S, Fineschi S, Dalli J, Perretti M, Lungarella G ( 2012 ) . FPR1 Blockade And Smoking-Induced Lung Emphysema In Mice . D80. EMPHYSEMA AND COPD: PATHOPHYSIOLOGY . Conference: American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, CaliforniaA6403 - A6403 .
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M ( 2012 ) . Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions . The FASEB Journal . vol. 26 ,
Serhan CN, Dalli J, Karamnov S, Choi A, Park C, Xu Z, Ji R, Zhu M et al. ( 2012 ) . Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain . The FASEB Journal vol. 26 , ( 4 ) 1755 - 1765 .
Dalli J, Montero-Melendez T, McArthur S, Perretti M ( 2012 ) . Annexin A1 N-Terminal Derived Peptide Ac2-26 Exerts Chemokinetic Effects on Human Neutrophils . Frontiers in Pharmacology vol. 3 ,
Norling L, Dalli J, Flower R, Serhan C, Perretti M ( 2012 ) . RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS . RHEUMATOLOGY . vol. 51 , 47 - 48 .
Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M, Rankin SM ( 2011 ) . Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow . The FASEB Journal vol. 26 , ( 1 ) 387 - 396 .
Norling LV, Dalli J, Serhan CN, Perretti M ( 2011 ) . RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS . INFLAMMATION RESEARCH . vol. 60 , 60 - 60 .
Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G, Perretti M ( 2011 ) . Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A(4) Receptor and Operative in the Inflamed Microvasculature . J IMMUNOL vol. 186 , ( 8 ) 4905 - 4914 .
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al. ( 2011 ) . Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation (vol 184, pg 2611, 2010) . J IMMUNOL vol. 186 , ( 4 ) 2684 - 2685 .
Brown SM, Dalli J, Perretti M, Bush A, Davies JC, Lloyd CM ( 2011 ) . THE INFLAMMATORY RESOLUTION PROTEIN ANNEXIN A1 AND THE PAEDIATRIC CF AIRWAY . PEDIATR PULM265 - 266 .
Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F ( 2010 ) . Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature . BLOOD vol. 116 , ( 20 ) 4288 - 4296 .
Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, Godson C ( 2010 ) . FPR2/ALX receptor expression and internalization are critical for lipoxin A(4) and annexin-derived peptide-stimulated phagocytosis . FASEB J vol. 24 , ( 11 ) 4240 - 4249 .
Perretti M, Dalli J, Bolla M, Padron J ( 2010 ) . THE CINOD NCX 429 INHIBITS MICROVASCULAR INFLAMMATION THROUGH ITS NO-RELEASING PROPERTIES . OSTEOARTHRITIS AND CARTILAGE . vol. 18 , S251 - S251 .
Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M ( 2010 ) . Downstream Gene Activation of the Receptor ALX by the Agonist Annexin A1 . PLOS ONE vol. 5 , ( 9 ) Article e12771 ,
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M ( 2010 ) . Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions . FASEB JOURNAL vol. 24 ,
Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al. ( 2010 ) . Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation . J IMMUNOL vol. 184 , ( 5 ) 2611 - 2619 .
Dalli J, Hayhoe RPG, Rosignoli G, Edelman A, Perretti M ( 2010 ) . CFTR inhibition yields an inflammatory response associated with an imbalance of the Annexin-A1 pathway . EUR J CLIN INVEST vol. 40 , 47 - 47 .
Brancaleone V, Dalli J, Perretti M ( 2010 ) . Mobilization of Annexin A1 in human polymorphonuclear leukocytes (PMN) . EUR J CLIN INVEST . vol. 40 , 36 - 37 .
Dalli J, Rosignoli G, Hayhoe RPG, Edelman A, Perretti M ( 2010 ) . CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway . AMERICAN JOURNAL OF PATHOLOGY vol. 177 , ( 1 ) 176 - 186 .
Pederzoli-Ribeil M, Maione F, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F ( 2010 ) . \Super\ Annexin-A1: a novel tool to regulate neutrophil-driven inflammation? . EUROPEAN JOURNAL OF CLINICAL INVESTIGATION . vol. 40 , 47 - 47 .
Perretti M, Dalli J ( 2009 ) . Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics . BRIT J PHARMACOL vol. 158 , ( 4 ) 936 - 946 .
Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M, Oliani SM ( 2009 ) . Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation . The American Journal of Pathology vol. 174 , ( 1 ) 177 - 183 .
Dalli J, Norling LV, Renshaw D, Cooper D, Leung KY, Perretti M ( 2008 ) . Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles . BLOOD vol. 112 , ( 6 ) 2512 - 2519 .
Gavins FNE, Dalli J, Flower RJ, Granger DN, Perretti M ( 2007 ) . Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation . FASEB J vol. 21 , ( 8 ) 1751 - 1758 .
Renshaw D, Dalli J, Kamal A, Perretti M ( 2006 ) . Disinct patterns of gene expression induced by annexin 1 activation of the ALXR receptor in HEK293 cells . The FASEB Journal . vol. 20 ,
Renshaw D, Sawmynadan P, Dalli J, Perretti M ( 2006 ) . Glucocorticoid regulated expression of the anti‐inflammatory receptor ALXR . The FASEB Journal . vol. 20 ,
Devi D, Budikote Venkatappa MB, Mäkinen P, Örd T, Aavik E, Colas R, Dalli J, Ylä-Herttuala S . Pro-Resolving Lipoxin A4 Rescues Impaired Post-Ischemic Angiogenesis and Perfusion Recovery in Hyperlipidemic and Diabetic Mice .